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Volumn 12, Issue 1, 2015, Pages

Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

Author keywords

Aging; Blood brain barrier; Inflammation; Leukocyte infiltration; Neurodegenerative disorder; Neuroinflammation; Tight junction complex

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; OCCLUDIN; OCCLUDIN 1; PROTEIN ZO1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84928748740     PISSN: None     EISSN: 17424933     Source Type: Journal    
DOI: 10.1186/s12979-015-0029-9     Document Type: Article
Times cited : (211)

References (43)
  • 1
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • Zlokovic BV. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat Rev Neurosci. 2011;12:723-38.
    • (2011) Nat Rev Neurosci. , vol.12 , pp. 723-738
    • Zlokovic, B.V.1
  • 2
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic BV. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron. 2008;57:178-201.
    • (2008) Neuron. , vol.57 , pp. 178-201
    • Zlokovic, B.V.1
  • 4
    • 58549098084 scopus 로고    scopus 로고
    • Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis
    • Farrall AJ, Wardlaw JM. Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis. Neurobiol Aging. 2009;30:337-52.
    • (2009) Neurobiol Aging. , vol.30 , pp. 337-352
    • Farrall, A.J.1    Wardlaw, J.M.2
  • 5
    • 84867725055 scopus 로고    scopus 로고
    • Histopathological stainings and definitions of vascular disruptions in the elderly brain
    • De Reuck JL. Histopathological stainings and definitions of vascular disruptions in the elderly brain. Exp Gerontol. 2012;47:834-7.
    • (2012) Exp Gerontol. , vol.47 , pp. 834-837
    • De Reuck, J.L.1
  • 7
    • 84862782622 scopus 로고    scopus 로고
    • The influence of ageing in the cerebrospinal fluid concentrations of proteins that are derived from the choroid plexus, brain, and plasma
    • Chen CP, Chen RL, Preston JE. The influence of ageing in the cerebrospinal fluid concentrations of proteins that are derived from the choroid plexus, brain, and plasma. Exp Gerontol. 2012;47:323-8.
    • (2012) Exp Gerontol. , vol.47 , pp. 323-328
    • Chen, C.P.1    Chen, R.L.2    Preston, J.E.3
  • 8
    • 71549122565 scopus 로고    scopus 로고
    • Reproductive age-related changes in the blood brain barrier: expression of IgG and tight junction proteins
    • Bake S, Friedman JA, Sohrabji F. Reproductive age-related changes in the blood brain barrier: expression of IgG and tight junction proteins. Microvasc Res. 2009;78:413-24.
    • (2009) Microvasc Res. , vol.78 , pp. 413-424
    • Bake, S.1    Friedman, J.A.2    Sohrabji, F.3
  • 9
    • 84862793270 scopus 로고    scopus 로고
    • Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice
    • Lee P, Kim J, Williams R, Sandhir R, Gregory E, Brooks WM, et al. Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice. Exp Neurol. 2012;234:50-61.
    • (2012) Exp Neurol. , vol.234 , pp. 50-61
    • Lee, P.1    Kim, J.2    Williams, R.3    Sandhir, R.4    Gregory, E.5    Brooks, W.M.6
  • 11
    • 0033574558 scopus 로고    scopus 로고
    • Increased permeability of primary cultured brain microvessel endothelial cell monolayers following TNF-alpha exposure
    • Mark KS, Miller DW. Increased permeability of primary cultured brain microvessel endothelial cell monolayers following TNF-alpha exposure. Life Sci. 1999;64:1941-53.
    • (1999) Life Sci. , vol.64 , pp. 1941-1953
    • Mark, K.S.1    Miller, D.W.2
  • 12
    • 20444398140 scopus 로고    scopus 로고
    • Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway
    • Trickler WJ, Mayhan WG, Miller DW. Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway. Brain Res. 2005;1048:24-31.
    • (2005) Brain Res. , vol.1048 , pp. 24-31
    • Trickler, W.J.1    Mayhan, W.G.2    Miller, D.W.3
  • 14
    • 67349130899 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1beta levels and leakage of the blood-brain barrier
    • Tian W, Kyriakides TR. Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1beta levels and leakage of the blood-brain barrier. Matrix biology: journal of the International Society for Matrix Biology. 2009;28:148-59.
    • (2009) Matrix biology: journal of the International Society for Matrix Biology. , vol.28 , pp. 148-159
    • Tian, W.1    Kyriakides, T.R.2
  • 15
    • 77955853869 scopus 로고    scopus 로고
    • Ac-YVAD-CMK decreases blood-brain barrier degradation by inhibiting caspase-1 activation of interleukin-1beta in intracerebral hemorrhage mouse model
    • Wu B, Ma Q, Khatibi N, Chen W, Sozen T, Cheng O, et al. Ac-YVAD-CMK decreases blood-brain barrier degradation by inhibiting caspase-1 activation of interleukin-1beta in intracerebral hemorrhage mouse model. Translational stroke research. 2010;1:57-64.
    • (2010) Translational stroke research. , vol.1 , pp. 57-64
    • Wu, B.1    Ma, Q.2    Khatibi, N.3    Chen, W.4    Sozen, T.5    Cheng, O.6
  • 16
    • 79551643521 scopus 로고    scopus 로고
    • Herbal medicines and nutraceuticals for diabetic vascular complications: mechanisms of action and bioactive phytochemicals
    • Omar EA, Kam A, Alqahtani A, Li KM, Razmovski-Naumovski V, Nammi S, et al. Herbal medicines and nutraceuticals for diabetic vascular complications: mechanisms of action and bioactive phytochemicals. Curr Pharm Des. 2010;16:3776-807.
    • (2010) Curr Pharm Des. , vol.16 , pp. 3776-3807
    • Omar, E.A.1    Kam, A.2    Alqahtani, A.3    Li, K.M.4    Razmovski-Naumovski, V.5    Nammi, S.6
  • 17
    • 0036295560 scopus 로고    scopus 로고
    • The adhesion molecule ICAM-1 and its regulation in relation with the blood-brain barrier
    • Dietrich JB. The adhesion molecule ICAM-1 and its regulation in relation with the blood-brain barrier. J Neuroimmunol. 2002;128:58-68.
    • (2002) J Neuroimmunol. , vol.128 , pp. 58-68
    • Dietrich, J.B.1
  • 18
    • 33847785838 scopus 로고    scopus 로고
    • Adhesion and migration of polymorphonuclear leukocytes across human brain microvessel endothelial cells are differentially regulated by endothelial cell adhesion molecules and modulate monolayer permeability
    • Wong D, Prameya R, Dorovini-Zis K. Adhesion and migration of polymorphonuclear leukocytes across human brain microvessel endothelial cells are differentially regulated by endothelial cell adhesion molecules and modulate monolayer permeability. J Neuroimmunol. 2007;184:136-48.
    • (2007) J Neuroimmunol. , vol.184 , pp. 136-148
    • Wong, D.1    Prameya, R.2    Dorovini-Zis, K.3
  • 19
    • 0034574471 scopus 로고    scopus 로고
    • Adrenergic mediation of TNF alpha-stimulated ICAM-1 expression on human brain microvascular endothelial cells
    • Ohara Y, McCarron RM, Hoffman TT, Sugano H, Bembry J, Lenz FA, et al. Adrenergic mediation of TNF alpha-stimulated ICAM-1 expression on human brain microvascular endothelial cells. Acta Neurochir Suppl. 2000;76:117-20.
    • (2000) Acta Neurochir Suppl. , vol.76 , pp. 117-120
    • Ohara, Y.1    McCarron, R.M.2    Hoffman, T.T.3    Sugano, H.4    Bembry, J.5    Lenz, F.A.6
  • 20
    • 48749113945 scopus 로고    scopus 로고
    • Preischemic induction of TNF-alpha by physical exercise reduces blood-brain barrier dysfunction in stroke
    • Guo M, Lin V, Davis W, Huang T, Carranza A, Sprague S, et al. Preischemic induction of TNF-alpha by physical exercise reduces blood-brain barrier dysfunction in stroke. J Cereb Blood Flow Metab. 2008;28:1422-30.
    • (2008) J Cereb Blood Flow Metab. , vol.28 , pp. 1422-1430
    • Guo, M.1    Lin, V.2    Davis, W.3    Huang, T.4    Carranza, A.5    Sprague, S.6
  • 22
    • 79960102812 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha affects blood-brain barrier permeability in acetaminophen-induced acute liver failure
    • Wang W, Lv S, Zhou Y, Fu J, Li C, Liu P. Tumor necrosis factor-alpha affects blood-brain barrier permeability in acetaminophen-induced acute liver failure. Eur J Gastroenterol Hepatol. 2011;23:552-8.
    • (2011) Eur J Gastroenterol Hepatol. , vol.23 , pp. 552-558
    • Wang, W.1    Lv, S.2    Zhou, Y.3    Fu, J.4    Li, C.5    Liu, P.6
  • 25
    • 33747172229 scopus 로고    scopus 로고
    • Inflammaging, cytokines and aging: state of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology
    • Salvioli S, Capri M, Valensin S, Tieri P, Monti D, Ottaviani E, et al. Inflammaging, cytokines and aging: state of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology. Curr Pharm Des. 2006;12:3161-71.
    • (2006) Curr Pharm Des. , vol.12 , pp. 3161-3171
    • Salvioli, S.1    Capri, M.2    Valensin, S.3    Tieri, P.4    Monti, D.5    Ottaviani, E.6
  • 26
    • 58849137494 scopus 로고    scopus 로고
    • Hemolysate-induced expression of intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 expression in cultured brain microvascular endothelial cells via through ROS-dependent NF-kappaB pathways
    • Lu H, Shi JX, Zhang DM, Shen J, Lin YX, Hang CH, et al. Hemolysate-induced expression of intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 expression in cultured brain microvascular endothelial cells via through ROS-dependent NF-kappaB pathways. Cell Mol Neurobiol. 2009;29:87-95.
    • (2009) Cell Mol Neurobiol. , vol.29 , pp. 87-95
    • Lu, H.1    Shi, J.X.2    Zhang, D.M.3    Shen, J.4    Lin, Y.X.5    Hang, C.H.6
  • 28
    • 77949680076 scopus 로고    scopus 로고
    • Inhibition of telomerase activity alters tight junction protein expression and induces transendothelial migration of HIV-1-infected cells
    • Huang W, Rha GB, Chen L, Seelbach MJ, Zhang B, Andras IE, et al. Inhibition of telomerase activity alters tight junction protein expression and induces transendothelial migration of HIV-1-infected cells. Am J Physiol Heart Circ Physiol. 2010;298:H1136-45.
    • (2010) Am J Physiol Heart Circ Physiol. , vol.298 , pp. H1136-H1145
    • Huang, W.1    Rha, G.B.2    Chen, L.3    Seelbach, M.J.4    Zhang, B.5    Andras, I.E.6
  • 29
    • 58549116078 scopus 로고    scopus 로고
    • Inflammatory mediators and blood brain barrier disruption in fatal brain edema of diabetic ketoacidosis
    • Hoffman WH, Stamatovic SM, Andjelkovic AV. Inflammatory mediators and blood brain barrier disruption in fatal brain edema of diabetic ketoacidosis. Brain Res. 2009;1254:138-48.
    • (2009) Brain Res. , vol.1254 , pp. 138-148
    • Hoffman, W.H.1    Stamatovic, S.M.2    Andjelkovic, A.V.3
  • 30
    • 67650064909 scopus 로고    scopus 로고
    • Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice
    • Sozen T, Tsuchiyama R, Hasegawa Y, Suzuki H, Jadhav V, Nishizawa S, et al. Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice. Stroke. 2009;40:2519-25.
    • (2009) Stroke. , vol.40 , pp. 2519-2525
    • Sozen, T.1    Tsuchiyama, R.2    Hasegawa, Y.3    Suzuki, H.4    Jadhav, V.5    Nishizawa, S.6
  • 31
    • 0037971138 scopus 로고    scopus 로고
    • Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability
    • Didier N, Romero IA, Creminon C, Wijkhuisen A, Grassi J, Mabondzo A. Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability. J Neurochem. 2003;86:246-54.
    • (2003) J Neurochem. , vol.86 , pp. 246-254
    • Didier, N.1    Romero, I.A.2    Creminon, C.3    Wijkhuisen, A.4    Grassi, J.5    Mabondzo, A.6
  • 32
    • 9644259030 scopus 로고    scopus 로고
    • Hypoxia-induced changes in tight junction permeability of brain capillary endothelial cells are associated with IL-1beta and nitric oxide
    • Yamagata K, Tagami M, Takenaga F, Yamori Y, Itoh S. Hypoxia-induced changes in tight junction permeability of brain capillary endothelial cells are associated with IL-1beta and nitric oxide. Neurobiol Dis. 2004;17:491-9.
    • (2004) Neurobiol Dis. , vol.17 , pp. 491-499
    • Yamagata, K.1    Tagami, M.2    Takenaga, F.3    Yamori, Y.4    Itoh, S.5
  • 33
    • 0025647016 scopus 로고
    • Aging and sex influence the permeability of the blood-brain barrier in the rat
    • Saija A, Princi P, D'Amico N, De Pasquale R, Costa G. Aging and sex influence the permeability of the blood-brain barrier in the rat. Life Sci. 1990;47:2261-7.
    • (1990) Life Sci. , vol.47 , pp. 2261-2267
    • Saija, A.1    Princi, P.2    D'Amico, N.3    De Pasquale, R.4    Costa, G.5
  • 35
    • 77949523096 scopus 로고    scopus 로고
    • Differential effects of dietary fatty acids on the cerebral distribution of plasma-derived apo B lipoproteins with amyloid-beta
    • Takechi R, Galloway S, Pallebage-Gamarallage MM, Wellington CL, Johnsen RD, Dhaliwal SS, et al. Differential effects of dietary fatty acids on the cerebral distribution of plasma-derived apo B lipoproteins with amyloid-beta. Br J Nutr. 2010;103:652-62.
    • (2010) Br J Nutr. , vol.103 , pp. 652-662
    • Takechi, R.1    Galloway, S.2    Pallebage-Gamarallage, M.M.3    Wellington, C.L.4    Johnsen, R.D.5    Dhaliwal, S.S.6
  • 36
    • 84866150126 scopus 로고    scopus 로고
    • Restoration of dietary-fat induced blood-brain barrier dysfunction by antiinflammatory lipid-modulating agents
    • Pallebage-Gamarallage M, Lam V, Takechi R, Galloway S, Clark K, Mamo J. Restoration of dietary-fat induced blood-brain barrier dysfunction by antiinflammatory lipid-modulating agents. Lipids Health Dis. 2012;11:117.
    • (2012) Lipids Health Dis. , vol.11 , pp. 117
    • Pallebage-Gamarallage, M.1    Lam, V.2    Takechi, R.3    Galloway, S.4    Clark, K.5    Mamo, J.6
  • 37
    • 84879066709 scopus 로고    scopus 로고
    • Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood-brain barrier function in wild-type mice
    • Takechi R, Pallebage-Gamarallage MM, Lam V, Giles C, Mamo JC. Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood-brain barrier function in wild-type mice. J Neuroinflammation. 2013;10:73.
    • (2013) J Neuroinflammation. , vol.10 , pp. 73
    • Takechi, R.1    Pallebage-Gamarallage, M.M.2    Lam, V.3    Giles, C.4    Mamo, J.C.5
  • 38
    • 84902551002 scopus 로고    scopus 로고
    • Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction
    • Takechi R, Pallebage-Gamarallage MM, Lam V, Giles C, Mamo JC. Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction. Lipids Health Dis. 2014;13:91.
    • (2014) Lipids Health Dis. , vol.13 , pp. 91
    • Takechi, R.1    Pallebage-Gamarallage, M.M.2    Lam, V.3    Giles, C.4    Mamo, J.C.5
  • 39
    • 84883179964 scopus 로고    scopus 로고
    • Rapid copper acquisition by developing murine mesothelioma: decreasing bioavailable copper slows tumor growth, normalizes vessels and promotes T cell infiltration
    • Crowe A, Jackaman C, Beddoes KM, Ricciardo B, Nelson DJ. Rapid copper acquisition by developing murine mesothelioma: decreasing bioavailable copper slows tumor growth, normalizes vessels and promotes T cell infiltration. PLoS One. 2013;8:e73684.
    • (2013) PLoS One. , vol.8
    • Crowe, A.1    Jackaman, C.2    Beddoes, K.M.3    Ricciardo, B.4    Nelson, D.J.5
  • 40
    • 84869204009 scopus 로고    scopus 로고
    • Hyaluronan fragments improve wound healing on in vitro cutaneous model through P2X7 purinoreceptor basal activation: role of molecular weight
    • Ghazi K, Deng-Pichon U, Warnet JM, Rat P. Hyaluronan fragments improve wound healing on in vitro cutaneous model through P2X7 purinoreceptor basal activation: role of molecular weight. PLoS One. 2012;7:e48351.
    • (2012) PLoS One. , vol.7
    • Ghazi, K.1    Deng-Pichon, U.2    Warnet, J.M.3    Rat, P.4
  • 41
    • 0031732526 scopus 로고    scopus 로고
    • Partial characterization of the human retinal endothelial cell tight and adherens junction complexes
    • Russ PK, Davidson MK, Hoffman LH, Haselton FR. Partial characterization of the human retinal endothelial cell tight and adherens junction complexes. Invest Ophthalmol Vis Sci. 1998;39:2479-85.
    • (1998) Invest Ophthalmol Vis Sci. , vol.39 , pp. 2479-2485
    • Russ, P.K.1    Davidson, M.K.2    Hoffman, L.H.3    Haselton, F.R.4
  • 42
    • 79952443665 scopus 로고    scopus 로고
    • Colocalisation of plasma derived apo B lipoproteins with cerebral proteoglycans in a transgenic-amyloid model of Alzheimer's disease
    • Lam V, Takechi R, Pallebage-Gamarallage MM, Galloway S, Mamo JC. Colocalisation of plasma derived apo B lipoproteins with cerebral proteoglycans in a transgenic-amyloid model of Alzheimer's disease. Neurosci Lett. 2011;492:160-4.
    • (2011) Neurosci Lett. , vol.492 , pp. 160-164
    • Lam, V.1    Takechi, R.2    Pallebage-Gamarallage, M.M.3    Galloway, S.4    Mamo, J.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.