Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid β-42 and α-synuclein in children and young adults

Toxicologic Pathology

Volumn 36, Issue 2, 2008, Pages 289-310

  Calderón Garcidueñas, Lilian ^a,b   Solt, Anna C ^c   Henríquez Roldán, Carlos ^d   Torres Jardón, Ricardo ^e   Nuse, Bryan ^b   Herritt, Lou ^b   Villarreal Calderón, Rafael ^b   Osnaya, Norma ^a   Stone, Ida ^b   García, Raquel ^a   Brooks, Diane M ^b   González Maciel, Angelica ^a   Reynoso Robles, Rafael ^a   Delgado Chávez, Ricardo ^f   Reed, William ^g  

^a INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^b UNIVERSITY OF MONTANA   (United States)

^c HARVARD UNIVERSITY   (United States)

^d UNIVERSIDAD DE VALPARAÍSO   (Chile)

^e UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^f INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

^g UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

synuclein; Air pollution; Alzheimer's disease; Amyloid 42; Neuroinflammation; Parkinson's disease; Ultrafine particulate matter

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN E; APOLIPOPROTEIN E4; CD14 ANTIGEN; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; MESSENGER RNA;

ADOLESCENT; ADULT; AIR POLLUTION; ARTICLE; BLOOD BRAIN BARRIER; BRAIN REGION; CELL MIGRATION; CHILD; CLINICAL ARTICLE; DISEASE ASSOCIATION; ENCEPHALITIS; ENDOTHELIUM CELL; ERYTHROCYTE; FEMALE; FRONTAL CORTEX; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; INFLAMMATORY CELL; INNATE IMMUNITY; LUNG; MALE; NERVE DEGENERATION; OLFACTORY BULB; OLFACTORY NERVE; OXIDATIVE STRESS; PARTICULATE MATTER; PEDIATRICS; PRIORITY JOURNAL; RESIDENTIAL AREA; SUBSTANTIA NIGRA; UPREGULATION; URBAN AREA; VAGUS NERVE;

ADOLESCENT; ADULT; AIR POLLUTANTS; ALPHA-SYNUCLEIN; AMYLOID BETA-PROTEIN; ANTIGENS, CD14; BLOOD-BRAIN BARRIER; BRAIN; CHILD; CHILD, PRESCHOOL; CYCLOOXYGENASE 2; ENCEPHALITIS; FEMALE; HUMANS; INTERLEUKIN-1BETA; MALE; NEURONS; OLFACTORY BULB; PARTICULATE MATTER; PEPTIDE FRAGMENTS; RNA, MESSENGER; UP-REGULATION; URBAN HEALTH; VAGUS NERVE;

EID: 42149103828     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623307313011     Document Type: Article

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