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Volumn 594, Issue 8, 2016, Pages 2095-2113

The role of oxysterols in vascular ageing

Author keywords

[No Author keywords available]

Indexed keywords

22 HYDROXYCHOLESTEROL; 25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; 7 OXOCHOLESTEROL; 7ALPHA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; ALPHA TOCOPHEROL; ASCORBIC ACID; OXIDIZED LOW DENSITY LIPOPROTEIN; OXYSTEROL;

EID: 84955612827     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/JP271168     Document Type: Review
Times cited : (70)

References (125)
  • 1
    • 49049106536 scopus 로고    scopus 로고
    • Low density lipoprotein has an enormous capacity to bind (E)-4-hydroxynon-2-enal (HNE): detection and characterization of lysyl and histidyl adducts containing multiple molecules of HNE
    • Annangudi SP, Deng Y, Gu X, Zhang W, Crabb JW & Salomon RG (2008). Low density lipoprotein has an enormous capacity to bind (E)-4-hydroxynon-2-enal (HNE): detection and characterization of lysyl and histidyl adducts containing multiple molecules of HNE. Chem Res Toxicol 21, 1384-1395.
    • (2008) Chem Res Toxicol , vol.21 , pp. 1384-1395
    • Annangudi, S.P.1    Deng, Y.2    Gu, X.3    Zhang, W.4    Crabb, J.W.5    Salomon, R.G.6
  • 2
    • 84883209270 scopus 로고    scopus 로고
    • Oxysterol-induced apoptosis of smooth muscle cells is under the control of a soluble adenylyl cyclase
    • Appukuttan A, Kassecker SA, Kumar S, Reusch HP & Ladilov Y (2013). Oxysterol-induced apoptosis of smooth muscle cells is under the control of a soluble adenylyl cyclase. Cardiovasc Res 99, 734-742.
    • (2013) Cardiovasc Res , vol.99 , pp. 734-742
    • Appukuttan, A.1    Kassecker, S.A.2    Kumar, S.3    Reusch, H.P.4    Ladilov, Y.5
  • 4
    • 70449528623 scopus 로고    scopus 로고
    • Prooxidant and proapoptotic effects of cholesterol oxidation products on human colonic epithelial cells: a potential mechanism of inflammatory bowel disease progression
    • Biasi F, Mascia C, Astegiano M, Chiarpotto E, Nano M, Leonarduzzi G & Poli G (2009). Prooxidant and proapoptotic effects of cholesterol oxidation products on human colonic epithelial cells: a potential mechanism of inflammatory bowel disease progression. Free Radic Biol Med 47, 1731-1741.
    • (2009) Free Radic Biol Med , vol.47 , pp. 1731-1741
    • Biasi, F.1    Mascia, C.2    Astegiano, M.3    Chiarpotto, E.4    Nano, M.5    Leonarduzzi, G.6    Poli, G.7
  • 6
    • 84907455071 scopus 로고    scopus 로고
    • Nox family NADPH oxidases: Molecular mechanisms of activation
    • Brandes RP, Weissmann N & Schröder K (2014). Nox family NADPH oxidases: Molecular mechanisms of activation. Free Radic Biol Med 76, 208-226.
    • (2014) Free Radic Biol Med , vol.76 , pp. 208-226
    • Brandes, R.P.1    Weissmann, N.2    Schröder, K.3
  • 7
    • 34447329708 scopus 로고    scopus 로고
    • Vascular endothelium and blood flow
    • Busse R & Fleming I (2006). Vascular endothelium and blood flow. Handb Exp Pharmacol 176, 43-78.
    • (2006) Handb Exp Pharmacol , vol.176 , pp. 43-78
    • Busse, R.1    Fleming, I.2
  • 10
    • 36749052290 scopus 로고    scopus 로고
    • Low-density lipoproteins induce the renin-angiotensin system and their receptors in human endothelial cells
    • Catar R, Müller G, Heidler J, Schmitz G, Bornstein SR & Morawietz H (2007). Low-density lipoproteins induce the renin-angiotensin system and their receptors in human endothelial cells. Horm Metab Res 39, 801-805.
    • (2007) Horm Metab Res , vol.39 , pp. 801-805
    • Catar, R.1    Müller, G.2    Heidler, J.3    Schmitz, G.4    Bornstein, S.R.5    Morawietz, H.6
  • 13
    • 30044433591 scopus 로고    scopus 로고
    • Cross-talk between dyslipidemia and renin-angiotensin system and the role of LOX-1 and MAPK in atherogenesis studies with the combined use of rosuvastatin and candesartan
    • Chen J, Li D, Schaefer R & Mehta JL (2006). Cross-talk between dyslipidemia and renin-angiotensin system and the role of LOX-1 and MAPK in atherogenesis studies with the combined use of rosuvastatin and candesartan. Atherosclerosis 184, 295-301.
    • (2006) Atherosclerosis , vol.184 , pp. 295-301
    • Chen, J.1    Li, D.2    Schaefer, R.3    Mehta, J.L.4
  • 14
    • 13844255073 scopus 로고    scopus 로고
    • Cholesterol-3-beta, 5-alpha, 6-beta-triol induced genotoxicity through reactive oxygen species formation
    • Cheng YW, Kang J, Shih YL, Lo YL & Wang C (2005). Cholesterol-3-beta, 5-alpha, 6-beta-triol induced genotoxicity through reactive oxygen species formation. Food Chem Toxicol 43, 617-622.
    • (2005) Food Chem Toxicol , vol.43 , pp. 617-622
    • Cheng, Y.W.1    Kang, J.2    Shih, Y.L.3    Lo, Y.L.4    Wang, C.5
  • 15
    • 0030888117 scopus 로고    scopus 로고
    • Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery
    • Cohen R, Plane F, Najibi S, Huk I, Malinski T & Garland C (1997). Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery. Proc Natl Acad Sci USA 94, 4193-4198.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4193-4198
    • Cohen, R.1    Plane, F.2    Najibi, S.3    Huk, I.4    Malinski, T.5    Garland, C.6
  • 16
    • 33947716172 scopus 로고    scopus 로고
    • Endothelial function and dysfunction: testing and clinical relevance
    • Deanfield JE, Halcox JP & Rabelink TJ (2007). Endothelial function and dysfunction: testing and clinical relevance. Circulation 115, 1285-1295.
    • (2007) Circulation , vol.115 , pp. 1285-1295
    • Deanfield, J.E.1    Halcox, J.P.2    Rabelink, T.J.3
  • 18
    • 0031046475 scopus 로고    scopus 로고
    • Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins. Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation
    • Deckert V, Perségol L, Viens L, Lizard G, Athias A, Lallemant C, Gambert P & Lagrost L (1997). Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins. Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation. Circulation 95, 723-731.
    • (1997) Circulation , vol.95 , pp. 723-731
    • Deckert, V.1    Perségol, L.2    Viens, L.3    Lizard, G.4    Athias, A.5    Lallemant, C.6    Gambert, P.7    Lagrost, L.8
  • 21
    • 84925664790 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein increases bone sialoprotein expression in vascular smooth muscle cells via runt-related transcription factor 2
    • Farrokhi E, Samani K & Chaleshtori M (2015). Oxidized low-density lipoprotein increases bone sialoprotein expression in vascular smooth muscle cells via runt-related transcription factor 2. Am J Med Sci 349, 240-243.
    • (2015) Am J Med Sci , vol.349 , pp. 240-243
    • Farrokhi, E.1    Samani, K.2    Chaleshtori, M.3
  • 26
    • 84924370418 scopus 로고    scopus 로고
    • Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability
    • Gargiulo S, Gamba P, Testa G, Rossin D, Biasi F, Poli G & Leonarduzzi G (2015). Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability. Aging Cell 14, 569-581.
    • (2015) Aging Cell , vol.14 , pp. 569-581
    • Gargiulo, S.1    Gamba, P.2    Testa, G.3    Rossin, D.4    Biasi, F.5    Poli, G.6    Leonarduzzi, G.7
  • 27
    • 79960933719 scopus 로고    scopus 로고
    • Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions
    • Gargiulo S, Sottero B, Gamba P, Chiarpotto E, Poli G & Leonarduzzi G (2011). Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions. Free Radic Biol Med 51, 844-855.
    • (2011) Free Radic Biol Med , vol.51 , pp. 844-855
    • Gargiulo, S.1    Sottero, B.2    Gamba, P.3    Chiarpotto, E.4    Poli, G.5    Leonarduzzi, G.6
  • 28
    • 36348954964 scopus 로고    scopus 로고
    • Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion
    • Go YM, Halvey PJ, Hansen JM, Reed M, Pohl J & Jones DP (2007). Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion. Am J Pathol 171, 1670-1681.
    • (2007) Am J Pathol , vol.171 , pp. 1670-1681
    • Go, Y.M.1    Halvey, P.J.2    Hansen, J.M.3    Reed, M.4    Pohl, J.5    Jones, D.P.6
  • 30
    • 84947044617 scopus 로고    scopus 로고
    • Oxidized LDL and NO synthesis - Biomarkers of endothelial dysfunction and ageing
    • Gradinaru D, Borsa C, Ionescu C & Prada GI (2015). Oxidized LDL and NO synthesis - Biomarkers of endothelial dysfunction and ageing. Mech Ageing Dev 151, 101-113.
    • (2015) Mech Ageing Dev , vol.151 , pp. 101-113
    • Gradinaru, D.1    Borsa, C.2    Ionescu, C.3    Prada, G.I.4
  • 31
    • 0035097953 scopus 로고    scopus 로고
    • Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction
    • Hamilton CA, Brosnan MJ, McIntyre M, Graham D & Dominiczak AF (2001). Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension 37, 529-534.
    • (2001) Hypertension , vol.37 , pp. 529-534
    • Hamilton, C.A.1    Brosnan, M.J.2    McIntyre, M.3    Graham, D.4    Dominiczak, A.F.5
  • 32
    • 0031443412 scopus 로고    scopus 로고
    • Endothelial function and oxidant stress
    • II-11-17
    • Harrison DG (1997). Endothelial function and oxidant stress. Clin Cardiol 20, II-11-17.
    • (1997) Clin Cardiol , vol.20
    • Harrison, D.G.1
  • 33
    • 84937969068 scopus 로고    scopus 로고
    • Vascular biology of ageing - implications in hypertension
    • Harvey A, Montezano A & Touyz RM (2015). Vascular biology of ageing - implications in hypertension. J Mol Cell Cardiol 83, 112-121.
    • (2015) J Mol Cell Cardiol , vol.83 , pp. 112-121
    • Harvey, A.1    Montezano, A.2    Touyz, R.M.3
  • 34
    • 84881234258 scopus 로고    scopus 로고
    • Fast LC-MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque
    • Helmschrodt C, Becker S, Schröter J, Hecht M, Aust G, Thiery J & Ceglarek U (2013). Fast LC-MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque. Clin Chim Acta 425, 3-8.
    • (2013) Clin Chim Acta , vol.425 , pp. 3-8
    • Helmschrodt, C.1    Becker, S.2    Schröter, J.3    Hecht, M.4    Aust, G.5    Thiery, J.6    Ceglarek, U.7
  • 38
    • 84898816567 scopus 로고    scopus 로고
    • Oxysterols and symptomatic versus asymptomatic human atherosclerotic plaque
    • Khatib S & Vaya J (2014). Oxysterols and symptomatic versus asymptomatic human atherosclerotic plaque. Biochem Biophys Res Commun 446, 709-713.
    • (2014) Biochem Biophys Res Commun , vol.446 , pp. 709-713
    • Khatib, S.1    Vaya, J.2
  • 40
    • 84919934705 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol up-regulates CD14 and predisposes monocytic cells to superproduction of CCL2 in response to lipopolysaccharide
    • Kim SM, Kim BY, Eo SK, Kim CD & Kim K (2015). 27-Hydroxycholesterol up-regulates CD14 and predisposes monocytic cells to superproduction of CCL2 in response to lipopolysaccharide. Biochim Biophys Acta 1852, 442-450.
    • (2015) Biochim Biophys Acta , vol.1852 , pp. 442-450
    • Kim, S.M.1    Kim, B.Y.2    Eo, S.K.3    Kim, C.D.4    Kim, K.5
  • 41
    • 0035956929 scopus 로고    scopus 로고
    • Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis
    • Kokoszka JE, Coskun P, Esposito LA & Wallace DC (2001). Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis. Proc Natl Acad Sci USA 98, 2278-2283.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2278-2283
    • Kokoszka, J.E.1    Coskun, P.2    Esposito, L.A.3    Wallace, D.C.4
  • 42
    • 33847620225 scopus 로고    scopus 로고
    • Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases
    • Krause KH (2007). Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases. Exp Gerontol 42, 256-262.
    • (2007) Exp Gerontol , vol.42 , pp. 256-262
    • Krause, K.H.1
  • 43
    • 84920195072 scopus 로고    scopus 로고
    • Mitochondrial function contributes to oxysterol-induced osteogenic differentiation in mouse embryonic stem cells
    • Kwon IK, Lee SC, Hwang YS & Heo JS (2015). Mitochondrial function contributes to oxysterol-induced osteogenic differentiation in mouse embryonic stem cells. Biochim Biophys Acta 1854, 561-572.
    • (2015) Biochim Biophys Acta , vol.1854 , pp. 561-572
    • Kwon, I.K.1    Lee, S.C.2    Hwang, Y.S.3    Heo, J.S.4
  • 44
    • 84876991735 scopus 로고    scopus 로고
    • The reality of aging viewed from the arterial wall
    • Lakatta EG (2013). The reality of aging viewed from the arterial wall. Artery Res 7, 73-80.
    • (2013) Artery Res , vol.7 , pp. 73-80
    • Lakatta, E.G.1
  • 45
    • 0037085365 scopus 로고    scopus 로고
    • Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-α from human monocytes
    • Landis MS, Patel HV & Capone JP (2002). Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-α from human monocytes. J Biol Chem 277, 4713-4721.
    • (2002) J Biol Chem , vol.277 , pp. 4713-4721
    • Landis, M.S.1    Patel, H.V.2    Capone, J.P.3
  • 47
    • 0032421830 scopus 로고    scopus 로고
    • Different patterns of IL-1β secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7α-, 7β-hydroxycholesterol, or 7-ketocholesterol
    • Lemaire S, Lizard G, Monier S, Miguet C, Gueldry S, Volot F, Gambert P & Néel D (1998). Different patterns of IL-1β secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7α-, 7β-hydroxycholesterol, or 7-ketocholesterol. FEBS Lett 440, 434-439.
    • (1998) FEBS Lett , vol.440 , pp. 434-439
    • Lemaire, S.1    Lizard, G.2    Monier, S.3    Miguet, C.4    Gueldry, S.5    Volot, F.6    Gambert, P.7    Néel, D.8
  • 48
    • 65349111246 scopus 로고    scopus 로고
    • 7β-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent
    • Lemaire-Ewing S, Berthier A, Royer MC, Logette E, Corcos L, Bouchot A, Monier S, Prunet C, Raveneau M, Rébé C, Desrumaux C, Lizard G & Néel D (2009). 7β-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent. Cell Biol Toxicol 25, 127-139.
    • (2009) Cell Biol Toxicol , vol.25 , pp. 127-139
    • Lemaire-Ewing, S.1    Berthier, A.2    Royer, M.C.3    Logette, E.4    Corcos, L.5    Bouchot, A.6    Monier, S.7    Prunet, C.8    Raveneau, M.9    Rébé, C.10    Desrumaux, C.11    Lizard, G.12    Néel, D.13
  • 49
    • 84655169879 scopus 로고    scopus 로고
    • Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis
    • Leonarduzzi G, Gamba P, Gargiulo S, Biasi F & Poli G (2012). Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis. Free Radic Biol Med 52, 19-34.
    • (2012) Free Radic Biol Med , vol.52 , pp. 19-34
    • Leonarduzzi, G.1    Gamba, P.2    Gargiulo, S.3    Biasi, F.4    Poli, G.5
  • 50
    • 43449122464 scopus 로고    scopus 로고
    • Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture
    • Leonarduzzi G, Gamba P, Gargiulo S, Sottero B, Kadl A, Biasi F, Chiarpotto E, Leitinger N, Vendemiale G, Serviddio G & Poli G (2008). Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture. Aging Cell 7, 375-382.
    • (2008) Aging Cell , vol.7 , pp. 375-382
    • Leonarduzzi, G.1    Gamba, P.2    Gargiulo, S.3    Sottero, B.4    Kadl, A.5    Biasi, F.6    Chiarpotto, E.7    Leitinger, N.8    Vendemiale, G.9    Serviddio, G.10    Poli, G.11
  • 52
    • 77952325660 scopus 로고    scopus 로고
    • Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells
    • Leonarduzzi G, Gargiulo S, Gamba P, Perrelli MG, Castellano I, Sapino A, Sottero B & Poli G (2010). Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells. Mol Nutr Food Res 54, Suppl. 1, S31-41.
    • (2010) Mol Nutr Food Res , vol.54 , pp. S31-S41
    • Leonarduzzi, G.1    Gargiulo, S.2    Gamba, P.3    Perrelli, M.G.4    Castellano, I.5    Sapino, A.6    Sottero, B.7    Poli, G.8
  • 53
    • 34249790259 scopus 로고    scopus 로고
    • Activation of the mitochondrial pathway of apoptosis by oxysterols
    • Leonarduzzi G, Poli G, Sottero B & Biasi F (2007). Activation of the mitochondrial pathway of apoptosis by oxysterols. Front Biosci 12, 791-799.
    • (2007) Front Biosci , vol.12 , pp. 791-799
    • Leonarduzzi, G.1    Poli, G.2    Sottero, B.3    Biasi, F.4
  • 54
    • 0035403085 scopus 로고    scopus 로고
    • Up-regulation of the fibrogenic cytokine TGF-β1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis
    • Leonarduzzi G, Sevanian A, Sottero B, Arkan MC, Biasi F, Chiarpotto E, Basaga H & Poli G (2001). Up-regulation of the fibrogenic cytokine TGF-β1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis. FASEB J 15, 1619-1621.
    • (2001) FASEB J , vol.15 , pp. 1619-1621
    • Leonarduzzi, G.1    Sevanian, A.2    Sottero, B.3    Arkan, M.C.4    Biasi, F.5    Chiarpotto, E.6    Basaga, H.7    Poli, G.8
  • 56
    • 79959196891 scopus 로고    scopus 로고
    • Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols
    • Li W, Ghosh M, Eftekhari S & Yuan XM (2011). Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols. Biochem Biophys Res Commun 409, 711-716.
    • (2011) Biochem Biophys Res Commun , vol.409 , pp. 711-716
    • Li, W.1    Ghosh, M.2    Eftekhari, S.3    Yuan, X.M.4
  • 57
    • 84868550466 scopus 로고    scopus 로고
    • Cell death induced by 7-oxysterols via lysosomal and mitochondrial pathways is p53-dependent
    • Li W, Laskar A, Sultana N, Osman E, Ghosh M, Li Q & Yuan XM (2012). Cell death induced by 7-oxysterols via lysosomal and mitochondrial pathways is p53-dependent. Free Radic Biol Med 53, 2054-2061.
    • (2012) Free Radic Biol Med , vol.53 , pp. 2054-2061
    • Li, W.1    Laskar, A.2    Sultana, N.3    Osman, E.4    Ghosh, M.5    Li, Q.6    Yuan, X.M.7
  • 58
    • 0032916924 scopus 로고    scopus 로고
    • Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats
    • Li Z, Froehlich J, Galis Z & Lakatta EG (1999). Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats. Hypertension 33, 116-123.
    • (1999) Hypertension , vol.33 , pp. 116-123
    • Li, Z.1    Froehlich, J.2    Galis, Z.3    Lakatta, E.G.4
  • 59
    • 77953959947 scopus 로고    scopus 로고
    • 7-Ketocholesterol and cholesterol-5α,6α-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways
    • Liao P, Cheng Y, Li C, Wang YT & Kang J (2010). 7-Ketocholesterol and cholesterol-5α, 6α-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways. Toxicol Lett 197, 88-96.
    • (2010) Toxicol Lett , vol.197 , pp. 88-96
    • Liao, P.1    Cheng, Y.2    Li, C.3    Wang, Y.T.4    Kang, J.5
  • 61
    • 8844228191 scopus 로고    scopus 로고
    • Cholestane-3β, 5α, 6β-triol promotes vascular smooth muscle cells calcification
    • Liu H, Yuan L, Xu S, Zhang T & Wang K (2004). Cholestane-3β, 5α, 6β-triol promotes vascular smooth muscle cells calcification. Life Sci 76, 533-543.
    • (2004) Life Sci , vol.76 , pp. 533-543
    • Liu, H.1    Yuan, L.2    Xu, S.3    Zhang, T.4    Wang, K.5
  • 62
    • 84899512017 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein increases the proliferation and migration of human coronary artery smooth muscle cells through the upregulation of osteopontin
    • Liu J, Ren Y, Kang L & Zhang L (2014). Oxidized low-density lipoprotein increases the proliferation and migration of human coronary artery smooth muscle cells through the upregulation of osteopontin. Int J Mol Med 33, 1341-1347.
    • (2014) Int J Mol Med , vol.33 , pp. 1341-1347
    • Liu, J.1    Ren, Y.2    Kang, L.3    Zhang, L.4
  • 63
    • 0031729620 scopus 로고    scopus 로고
    • Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production
    • Lizard G, Gueldry S, Sordet O, Monier S, Athias A, Miguet C, Bessede G, Lemaire S, Solary E & Gambert P (1998). Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production. FASEB J 12, 1651-1663.
    • (1998) FASEB J , vol.12 , pp. 1651-1663
    • Lizard, G.1    Gueldry, S.2    Sordet, O.3    Monier, S.4    Athias, A.5    Miguet, C.6    Bessede, G.7    Lemaire, S.8    Solary, E.9    Gambert, P.10
  • 64
    • 63249096864 scopus 로고    scopus 로고
    • Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases
    • Lordan S, Mackrill JJ & O'Brien NM (2009). Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases. J Nutr Biochem 20, 321-336.
    • (2009) J Nutr Biochem , vol.20 , pp. 321-336
    • Lordan, S.1    Mackrill, J.J.2    O'Brien, N.M.3
  • 66
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ (2000). Atherosclerosis. Nature 407, 233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 67
    • 84900559975 scopus 로고    scopus 로고
    • The molecular biology and pathophysiology of vascular calcification
    • McCarthy MF & DiNicolantonio JJ (2014). The molecular biology and pathophysiology of vascular calcification. Postgrad Med 126, 54-64.
    • (2014) Postgrad Med , vol.126 , pp. 54-64
    • McCarthy, M.F.1    DiNicolantonio, J.J.2
  • 68
    • 78650175733 scopus 로고    scopus 로고
    • Proinflammatory effect of cholesterol oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocathechin-3-gallate
    • Mascia C, Maina M, Chiarpotto E, Leonarduzzi G, Poli G & Biasi F (2010). Proinflammatory effect of cholesterol oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocathechin-3-gallate. Free Radic Biol Med 49, 2049-2057.
    • (2010) Free Radic Biol Med , vol.49 , pp. 2049-2057
    • Mascia, C.1    Maina, M.2    Chiarpotto, E.3    Leonarduzzi, G.4    Poli, G.5    Biasi, F.6
  • 70
    • 84878358772 scopus 로고    scopus 로고
    • Expression of Egr1 and p53 in human carotid plaques and apoptosis induced by 7-oxysterol or p53
    • Miah S, Zadeh SN, Yuan XM & Li W (2013). Expression of Egr1 and p53 in human carotid plaques and apoptosis induced by 7-oxysterol or p53. Exp Toxicol Pathol 65, 677-682.
    • (2013) Exp Toxicol Pathol , vol.65 , pp. 677-682
    • Miah, S.1    Zadeh, S.N.2    Yuan, X.M.3    Li, W.4
  • 71
    • 77952891006 scopus 로고    scopus 로고
    • Cellular signaling and NO production
    • Michel T & Vanhoutte PM (2010). Cellular signaling and NO production. Pflugers Arch 459, 807-816.
    • (2010) Pflugers Arch , vol.459 , pp. 807-816
    • Michel, T.1    Vanhoutte, P.M.2
  • 72
    • 0347753266 scopus 로고    scopus 로고
    • Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque
    • Micheletta F, Natoli S, Misuraca M, Sbarigia E, Diczfalusy U & Iuliano L (2004). Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque. Arterioscler Thromb Vasc Biol 24, 136-140.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 136-140
    • Micheletta, F.1    Natoli, S.2    Misuraca, M.3    Sbarigia, E.4    Diczfalusy, U.5    Iuliano, L.6
  • 73
    • 0025883342 scopus 로고
    • Nitric oxide: physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer R & Higgs E (1991). Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43, 109-142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.2    Higgs, E.3
  • 74
    • 84942088907 scopus 로고    scopus 로고
    • The effect of ageing on vascular smooth muscle cell behaviour - a mini-review
    • Monk BA & George SJ (2014). The effect of ageing on vascular smooth muscle cell behaviour - a mini-review. Gerontology 61, 416-426.
    • (2014) Gerontology , vol.61 , pp. 416-426
    • Monk, B.A.1    George, S.J.2
  • 77
    • 84860918905 scopus 로고    scopus 로고
    • Molecular mechanisms of hypertension - reactive oxygen species and antioxidants: a basic science update for the clinician
    • Montezano AC & Touyz RM (2012). Molecular mechanisms of hypertension - reactive oxygen species and antioxidants: a basic science update for the clinician. Can J Cardiol 28, 288-295.
    • (2012) Can J Cardiol , vol.28 , pp. 288-295
    • Montezano, A.C.1    Touyz, R.M.2
  • 84
    • 0027235869 scopus 로고
    • Effect of cholesterol oxides on prostacyclin production and platelet adhesion
    • Peng SK, Hu B, Peng AY & Morin R (1993). Effect of cholesterol oxides on prostacyclin production and platelet adhesion. Artery 20, 122-134.
    • (1993) Artery , vol.20 , pp. 122-134
    • Peng, S.K.1    Hu, B.2    Peng, A.Y.3    Morin, R.4
  • 85
    • 84878798159 scopus 로고    scopus 로고
    • Oxysterols in the pathogenesis of major chronic diseases
    • Poli G, Biasi F & Leonarduzzi G (2013). Oxysterols in the pathogenesis of major chronic diseases. Redox Biol 1, 125-130.
    • (2013) Redox Biol , vol.1 , pp. 125-130
    • Poli, G.1    Biasi, F.2    Leonarduzzi, G.3
  • 86
    • 67349248123 scopus 로고    scopus 로고
    • Cholesterol oxidation products in the vascular remodeling due to atherosclerosis
    • Poli G, Sottero B, Gargiulo S & Leonarduzzi G (2009). Cholesterol oxidation products in the vascular remodeling due to atherosclerosis. Mol Aspects Med 30, 180-189.
    • (2009) Mol Aspects Med , vol.30 , pp. 180-189
    • Poli, G.1    Sottero, B.2    Gargiulo, S.3    Leonarduzzi, G.4
  • 87
    • 0034711505 scopus 로고    scopus 로고
    • Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies
    • Proudfoot D, Skepper JN, Hegyi L, Bennett MR, Shanahan CM & Weissberg PL (2000). Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies. Circ Res 87, 1055-1062.
    • (2000) Circ Res , vol.87 , pp. 1055-1062
    • Proudfoot, D.1    Skepper, J.N.2    Hegyi, L.3    Bennett, M.R.4    Shanahan, C.M.5    Weissberg, P.L.6
  • 91
    • 0026615980 scopus 로고
    • Oxysterol-induced endothelial cell dysfunction in culture
    • Ramasamy S, Boissonneault GA & Hennig B (1992). Oxysterol-induced endothelial cell dysfunction in culture. J Am Coll Nutr 11, 532-538.
    • (1992) J Am Coll Nutr , vol.11 , pp. 532-538
    • Ramasamy, S.1    Boissonneault, G.A.2    Hennig, B.3
  • 92
    • 1542300884 scopus 로고    scopus 로고
    • Generation of an oxidative stress precedes caspase activation during 7β-hydroxycholesterol-induced apoptosis in U937 cells
    • Ryan L, O'Callaghan YC & O'Brien NM (2004). Generation of an oxidative stress precedes caspase activation during 7β-hydroxycholesterol-induced apoptosis in U937 cells. J Biochem Mol Toxicol 18, 50-59.
    • (2004) J Biochem Mol Toxicol , vol.18 , pp. 50-59
    • Ryan, L.1    O'Callaghan, Y.C.2    O'Brien, N.M.3
  • 93
    • 48849096990 scopus 로고    scopus 로고
    • 7-Ketocholesterol, a major oxysterol, promotes Pi-induced vascular calcification in cultured smooth muscle cells
    • Saito E, Wachi H, Sato F & Seyama Y (2008). 7-Ketocholesterol, a major oxysterol, promotes Pi-induced vascular calcification in cultured smooth muscle cells. J Atheroscler Thromb 15, 130-137.
    • (2008) J Atheroscler Thromb , vol.15 , pp. 130-137
    • Saito, E.1    Wachi, H.2    Sato, F.3    Seyama, Y.4
  • 94
    • 84870749692 scopus 로고    scopus 로고
    • Dietary cholesterol oxidation products accelerate plaque destabilization and rupture associated with monocyte infiltration/activation via the MCP-1-CCR2 pathway in mouse brachiocephalic arteries: therapeutic effects of ezetimibe
    • Sato K, Nakano K, Katsuki S, Matoba T, Osada K, Sawamura T, Sunagawa K & Egashira K (2012). Dietary cholesterol oxidation products accelerate plaque destabilization and rupture associated with monocyte infiltration/activation via the MCP-1-CCR2 pathway in mouse brachiocephalic arteries: therapeutic effects of ezetimibe. J Atheroscler Thromb 19, 986-998.
    • (2012) J Atheroscler Thromb , vol.19 , pp. 986-998
    • Sato, K.1    Nakano, K.2    Katsuki, S.3    Matoba, T.4    Osada, K.5    Sawamura, T.6    Sunagawa, K.7    Egashira, K.8
  • 95
    • 3242718855 scopus 로고    scopus 로고
    • From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension
    • Schiffrin EL & Touyz RM (2004). From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension. Am J Physiol Heart Circ Physiol 287, H435-H446.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287 , pp. H435-H446
    • Schiffrin, E.L.1    Touyz, R.M.2
  • 97
    • 77955878803 scopus 로고    scopus 로고
    • oxLDL-induced decrease in lipid order of membrane domains is inversely correlated with endothelial stiffness and network formation
    • Shentu TP, Titushkin I, Singh DK, Gooch KJ, Subbaiah PV, Cho M & Levitan I (2010). oxLDL-induced decrease in lipid order of membrane domains is inversely correlated with endothelial stiffness and network formation. Am J Physiol Cell Physiol 299, C218-C229.
    • (2010) Am J Physiol Cell Physiol , vol.299 , pp. C218-C229
    • Shentu, T.P.1    Titushkin, I.2    Singh, D.K.3    Gooch, K.J.4    Subbaiah, P.V.5    Cho, M.6    Levitan, I.7
  • 98
    • 84879165160 scopus 로고    scopus 로고
    • Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis
    • Sinha K, Das J, Pal PB & Sil PC (2013). Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis. Arch Toxicol 87, 1157-1180.
    • (2013) Arch Toxicol , vol.87 , pp. 1157-1180
    • Sinha, K.1    Das, J.2    Pal, P.B.3    Sil, P.C.4
  • 99
    • 0034749013 scopus 로고    scopus 로고
    • Interaction of caveolin with 7-ketocholesterol
    • Sleer LS, Brown AJ & Stanley KK (2001). Interaction of caveolin with 7-ketocholesterol. Atherosclerosis 159, 49-55.
    • (2001) Atherosclerosis , vol.159 , pp. 49-55
    • Sleer, L.S.1    Brown, A.J.2    Stanley, K.K.3
  • 100
    • 65649083410 scopus 로고    scopus 로고
    • Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry
    • Sottero B, Gamba P, Gargiulo S, Leonarduzzi G & Poli G (2009). Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry. Curr Med Chem 16, 685-705.
    • (2009) Curr Med Chem , vol.16 , pp. 685-705
    • Sottero, B.1    Gamba, P.2    Gargiulo, S.3    Leonarduzzi, G.4    Poli, G.5
  • 103
    • 23944457322 scopus 로고    scopus 로고
    • Mechanisms of selenium inhibition of cell apoptosis induced by oxysterols in rat vascular smooth muscle cells
    • Tang R, Liu H, Wang T & Huang K (2005). Mechanisms of selenium inhibition of cell apoptosis induced by oxysterols in rat vascular smooth muscle cells. Arch Biochem Biophys 441, 16-24.
    • (2005) Arch Biochem Biophys , vol.441 , pp. 16-24
    • Tang, R.1    Liu, H.2    Wang, T.3    Huang, K.4
  • 104
    • 84908450979 scopus 로고    scopus 로고
    • Endothelial cell senescence and age-related vascular diseases
    • Tian XL & Li Y (2014). Endothelial cell senescence and age-related vascular diseases. J Genet Genomics 41, 485-495.
    • (2014) J Genet Genomics , vol.41 , pp. 485-495
    • Tian, X.L.1    Li, Y.2
  • 106
    • 33845629703 scopus 로고    scopus 로고
    • Redox regulation of 4-hydroxy-2-nonenal-mediated endothelial barrier dysfunction by focal adhesion, adherens, and tight junction proteins
    • Usatyuk PV, Parinandi NL & Natarajan V (2006). Redox regulation of 4-hydroxy-2-nonenal-mediated endothelial barrier dysfunction by focal adhesion, adherens, and tight junction proteins. J Biol Chem 281, 35554-35566.
    • (2006) J Biol Chem , vol.281 , pp. 35554-35566
    • Usatyuk, P.V.1    Parinandi, N.L.2    Natarajan, V.3
  • 107
    • 82955237301 scopus 로고    scopus 로고
    • Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function
    • Usatyuk PV & Natarajan V (2012). Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function. Microvasc Res 83, 45-55.
    • (2012) Microvasc Res , vol.83 , pp. 45-55
    • Usatyuk, P.V.1    Natarajan, V.2
  • 108
    • 0035007094 scopus 로고    scopus 로고
    • Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins
    • Vaya J, Aviram M, Mahmood S, Hayek T, Grenadir E, Hoffman A & Milo S (2001). Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins. Free Radic Res 34, 485-497.
    • (2001) Free Radic Res , vol.34 , pp. 485-497
    • Vaya, J.1    Aviram, M.2    Mahmood, S.3    Hayek, T.4    Grenadir, E.5    Hoffman, A.6    Milo, S.7
  • 109
    • 57049189735 scopus 로고    scopus 로고
    • Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis
    • Vejux A, Guyot S, Montange T, Riedinger JM, Kahn E & Lizard G (2009). Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis. J Nutr Biochem 20, 45-61.
    • (2009) J Nutr Biochem , vol.20 , pp. 45-61
    • Vejux, A.1    Guyot, S.2    Montange, T.3    Riedinger, J.M.4    Kahn, E.5    Lizard, G.6
  • 112
    • 84863667325 scopus 로고    scopus 로고
    • Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence
    • Wang JC & Bennett M (2012). Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence. Circ Res 111, 245-259.
    • (2012) Circ Res , vol.111 , pp. 245-259
    • Wang, J.C.1    Bennett, M.2
  • 114
    • 0028180137 scopus 로고
    • TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify
    • Watson KE, Boström K, Ravindranath R, Lam T, Norton B & Demer L (1994). TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify. J Clin Invest 93, 2106-2113.
    • (1994) J Clin Invest , vol.93 , pp. 2106-2113
    • Watson, K.E.1    Boström, K.2    Ravindranath, R.3    Lam, T.4    Norton, B.5    Demer, L.6
  • 115
    • 77955980491 scopus 로고    scopus 로고
    • Oxidative stress and endothelial dysfunction in aortas of aged spontaneously hypertensive rats by NOX1/2 is reversed by NADPH oxidase inhibition
    • Wind S, Beuerlein K, Armitage M, Taye A, Kumar A, Janowitz D, Neff C, Shah AM, Wingler K & Schmidt HH (2010). Oxidative stress and endothelial dysfunction in aortas of aged spontaneously hypertensive rats by NOX1/2 is reversed by NADPH oxidase inhibition. Hypertension 56, 490-497.
    • (2010) Hypertension , vol.56 , pp. 490-497
    • Wind, S.1    Beuerlein, K.2    Armitage, M.3    Taye, A.4    Kumar, A.5    Janowitz, D.6    Neff, C.7    Shah, A.M.8    Wingler, K.9    Schmidt, H.H.10
  • 116
    • 0033398802 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol increases eicosanoids and alters morphology in cultured pulmonary artery smooth muscle and endothelial cells
    • Wohlfeil ER & Campbel WB (1999). 25-Hydroxycholesterol increases eicosanoids and alters morphology in cultured pulmonary artery smooth muscle and endothelial cells. Arterioscler Thromb Vasc Biol 19, 2901-2908.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2901-2908
    • Wohlfeil, E.R.1    Campbel, W.B.2
  • 118
    • 79951509868 scopus 로고    scopus 로고
    • Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta
    • Wong W, Ng CH, Tsang SY, Huang Y & Chen ZY (2011). Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta. Nutr Metab Cardiovasc Dis 21, 157-164.
    • (2011) Nutr Metab Cardiovasc Dis , vol.21 , pp. 157-164
    • Wong, W.1    Ng, C.H.2    Tsang, S.Y.3    Huang, Y.4    Chen, Z.Y.5
  • 120
    • 33947427515 scopus 로고    scopus 로고
    • Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence
    • Yang D, McCrann DJ, Nguyen H, St Hilaire C, DePinho RA, Jones MR & Ravid K (2007). Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence. Aging Cell 6, 257-260.
    • (2007) Aging Cell , vol.6 , pp. 257-260
    • Yang, D.1    McCrann, D.J.2    Nguyen, H.3    St Hilaire, C.4    DePinho, R.A.5    Jones, M.R.6    Ravid, K.7
  • 121
    • 0034736137 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol activates a cytochrome c release-mediated caspase cascade
    • Yang L & Sinensky M (2000). 25-Hydroxycholesterol activates a cytochrome c release-mediated caspase cascade. Biochem Biophys Res Commun 278, 557-563.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 557-563
    • Yang, L.1    Sinensky, M.2
  • 122
    • 77953229649 scopus 로고    scopus 로고
    • p53 expression in human carotid atheroma is significantly related to plaque instability and clinical manifestations
    • Yuan XM, Osman E, Miah S, Zadeh SN, Xu L, Forssell C & Li W (2010). p53 expression in human carotid atheroma is significantly related to plaque instability and clinical manifestations. Atherosclerosis 210, 392-399.
    • (2010) Atherosclerosis , vol.210 , pp. 392-399
    • Yuan, X.M.1    Osman, E.2    Miah, S.3    Zadeh, S.N.4    Xu, L.5    Forssell, C.6    Li, W.7


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