Cell death induced by 7-oxysterols via lysosomal and mitochondrial pathways is p53-dependent

Free Radical Biology and Medicine

Volumn 53, Issue 11, 2012, Pages 2054-2061

  Li, Wei ^a   Laskar, Amit ^a   Sultana, Nargis ^a   Osman, Ehab ^a   Ghosh, Moumita ^a   Li, Qianqian ^a   Yuan, Xi Ming ^a,b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Apoptosis; Atherosclerosis; Bax; Free radicals; Lysosomes; Mitochondria; Oxidative stress

Indexed keywords

7 OXYSTEROL; CYTOCHROME C; OXYSTEROL; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CELL STRESS; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; LYSOSOME; LYSOSOME MEMBRANE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; TEMPERATURE SENSITIVITY;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; CELL NUCLEUS; GENE EXPRESSION REGULATION; HUMANS; HYDROXYCHOLESTEROLS; INTRACELLULAR MEMBRANES; KETOCHOLESTEROLS; LYSOSOMES; MACROPHAGES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; NECROSIS; OXIDATIVE STRESS; PERMEABILITY; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-MDM2; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84868550466     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.09.007     Document Type: Article

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