메뉴 건너뛰기




Volumn 99, Issue 4, 2013, Pages 734-742

Oxysterol-induced apoptosis of smooth muscle cells is under the control of a soluble adenylyl cyclase

Author keywords

Apoptosis; Bax; Oxysterol; Protein kinase A; Soluble adenylyl cyclase

Indexed keywords

25 HYDROXYCHOLESTEROL; 7 OXOCHOLESTEROL; ADENYLATE CYCLASE; CASPASE 9; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHROME C; OXYSTEROL; PROTEIN BAX; REACTIVE OXYGEN METABOLITE;

EID: 84883209270     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt137     Document Type: Article
Times cited : (48)

References (41)
  • 1
    • 33751236171 scopus 로고    scopus 로고
    • Defining the role of vascular smooth muscle cell apoptosis in atherosclerosis
    • Clarke M, Bennett M. Defining the role of vascular smooth muscle cell apoptosis in atherosclerosis. Cell Cycle 2006;5:2329-2331.
    • (2006) Cell Cycle , vol.5 , pp. 2329-2331
    • Clarke, M.1    Bennett, M.2
  • 2
    • 0033021175 scopus 로고    scopus 로고
    • Role of smooth muscle cell death in advanced coronary primary lesions: Implications for plaque instability
    • Bauriedel G, Hutter R,Welsch U, Bach R, Sievert H, Luderitz B. Role of smooth muscle cell death in advanced coronary primary lesions: implications for plaque instability. Cardiovasc Res 1999;41:480-488.
    • (1999) Cardiovasc Res , vol.41 , pp. 480-488
    • Bauriedel, G.1    Hutter, R.2    Welsch, U.3    Bach, R.4    Sievert, H.5    Luderitz, B.6
  • 4
    • 0032890337 scopus 로고    scopus 로고
    • Oxysterols and atherosclerosis
    • Brown AJ, JessupW. Oxysterols and atherosclerosis. Atherosclerosis 1999;142:1-28.
    • (1999) Atherosclerosis , vol.142 , pp. 1-28
    • Brown, A.J.1    Jessup, W.2
  • 5
    • 15144341601 scopus 로고    scopus 로고
    • Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells
    • Ares MP, Porn-Ares MI, Thyberg J, Juntti-Berggren L, Berggren PO, Diczfalusy U et al. Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells. J Lipid Res 1997;38: 2049-2061.
    • (1997) J Lipid Res , vol.38 , pp. 2049-2061
    • Ares, M.P.1    Porn-Ares, M.I.2    Thyberg, J.3    Juntti-Berggren, L.4    Berggren, P.O.5    Diczfalusy, U.6
  • 7
    • 0037264053 scopus 로고    scopus 로고
    • Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains
    • Zippin JH, Chen Y, Nahirney P, Kamenetsky M, Wuttke MS, FischmanDAet al. Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains. FASEB J 2003;17:82-84.
    • (2003) FASEB J , vol.17 , pp. 82-84
    • Zippin, J.H.1    Chen, Y.2    Nahirney, P.3    Kamenetsky, M.4    Wuttke, M.S.5    Fischman, D.A.6
  • 8
    • 67649359964 scopus 로고    scopus 로고
    • Soluble adenylyl cyclase controls mitochondria-dependent apoptosis in coronary endothelial cells
    • Kumar S, Kostin S, Flacke JP, Reusch HP, Ladilov Y. Soluble adenylyl cyclase controls mitochondria-dependent apoptosis in coronary endothelial cells. J Biol Chem 2009; 284:14760-14768.
    • (2009) J Biol Chem , vol.284 , pp. 14760-14768
    • Kumar, S.1    Kostin, S.2    Flacke, J.P.3    Reusch, H.P.4    Ladilov, Y.5
  • 9
    • 84862943193 scopus 로고    scopus 로고
    • Type 10 adenylyl cyclase mediates mitochondrial Bax translocation and apoptosis of adult rat cardiomyocytes under simulated ischaemia/reperfusion
    • AppukuttanA, Kasseckert SA, Micoogullari M, Flacke JP, Kumar S,WosteAet al. Type 10 adenylyl cyclase mediates mitochondrial Bax translocation and apoptosis of adult rat cardiomyocytes under simulated ischaemia/reperfusion. Cardiovasc Res 2012;93: 340-349.
    • (2012) Cardiovasc Res , vol.93 , pp. 340-349
    • Appukuttan, A.1    Kasseckert, S.A.2    Micoogullari, M.3    Flacke, J.P.4    Kumar, S.5    Woste, A.6
  • 10
    • 77953567491 scopus 로고    scopus 로고
    • Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects
    • Acin-Perez R, Salazar E, Brosel S, Yang H, Schon EA, Manfredi G. Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects. EMBO Mol Med 2009;1:392-406.
    • (2009) EMBO Mol Med , vol.1 , pp. 392-406
    • Acin-Perez, R.1    Salazar, E.2    Brosel, S.3    Yang, H.4    Schon, E.A.5    Manfredi, G.6
  • 12
    • 0030060474 scopus 로고    scopus 로고
    • Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages
    • Hultén LM, Lindmark H, Diczfalusy U, Björkhem I, Ottosson M, Liu Y et al. Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages. J Clin Invest 1996;97:461-468.
    • (1996) J Clin Invest , vol.97 , pp. 461-468
    • Hultén, L.M.1    Lindmark, H.2    Diczfalusy, U.3    Björkhem, I.4    Ottosson, M.5    Liu, Y.6
  • 13
    • 22944450343 scopus 로고    scopus 로고
    • The 'soluble' adenylyl cyclase in sperm mediates multiple signaling events required for fertilization
    • Hess KC, Jones BH, Marquez B, Chen Y, Ord TS, Kamenetsky M et al. The 'soluble' adenylyl cyclase in sperm mediates multiple signaling events required for fertilization. Dev Cell 2005;9:249-259.
    • (2005) Dev Cell , vol.9 , pp. 249-259
    • Hess, K.C.1    Jones, B.H.2    Marquez, B.3    Chen, Y.4    Ord, T.S.5    Kamenetsky, M.6
  • 14
    • 21344443874 scopus 로고    scopus 로고
    • TNF-alpha activates death pathway in human aorta smooth muscle cell in the presence of 7-ketocholesterol
    • Lee HS, Chang JS, Baek JA, Chung MY, Lee HC, Rhim BY et al. TNF-alpha activates death pathway in human aorta smooth muscle cell in the presence of 7-ketocholesterol. Biochem Biophys Res Commun 2005;333:1093-1099.
    • (2005) Biochem Biophys Res Commun , vol.333 , pp. 1093-1099
    • Lee, H.S.1    Chang, J.S.2    Baek, J.A.3    Chung, M.Y.4    Lee, H.C.5    Rhim, B.Y.6
  • 15
    • 36348989007 scopus 로고    scopus 로고
    • Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway
    • Guo X, Chen KH, Guo Y, Liao H, Tang J, Xiao RP. Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway. Circ Res 2007;101:1113-1122.
    • (2007) Circ Res , vol.101 , pp. 1113-1122
    • Guo, X.1    Chen, K.H.2    Guo, Y.3    Liao, H.4    Tang, J.5    Xiao, R.P.6
  • 16
    • 78650414582 scopus 로고    scopus 로고
    • 7-ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-kappaB and Akt pathways
    • Jang ER, Lee CS. 7-ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-kappaB and Akt pathways. Neurochem Int 2011;58:52-59.
    • (2011) Neurochem Int , vol.58 , pp. 52-59
    • Jang, E.R.1    Lee, C.S.2
  • 17
    • 0031729620 scopus 로고    scopus 로고
    • Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production
    • Lizard G, Gueldry S, Sordet O, Monier S, Athias A, Miguet C et al. Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production. FASEB J 1998;12:1651-1663.
    • (1998) FASEB J , vol.12 , pp. 1651-1663
    • Lizard, G.1    Gueldry, S.2    Sordet, O.3    Monier, S.4    Athias, A.5    Miguet, C.6
  • 18
    • 0041315574 scopus 로고    scopus 로고
    • CAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension
    • Christensen AE, Selheim F, de Rooij J, Dremier S, Schwede F, Dao KK et al. cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension. J Biol Chem 2003;278:35394-35402.
    • (2003) J Biol Chem , vol.278 , pp. 35394-35402
    • Christensen, A.E.1    Selheim, F.2    De Rooij, J.3    Dremier, S.4    Schwede, F.5    Dao, K.K.6
  • 19
    • 0037386258 scopus 로고    scopus 로고
    • Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70
    • Sawada M, Hayes P, Matsuyama S. Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70. Nat Cell Biol 2003;5:352-357.
    • (2003) Nat Cell Biol , vol.5 , pp. 352-357
    • Sawada, M.1    Hayes, P.2    Matsuyama, S.3
  • 20
    • 0035185753 scopus 로고    scopus 로고
    • Oxidized LDL-induced injury and apoptosis in atherosclerosis. Potential roles for oxysterols
    • Colles SM, Maxson JM, Carlson SG, Chisolm GM. Oxidized LDL-induced injury and apoptosis in atherosclerosis. Potential roles for oxysterols. Trends Cardiovasc Med 2001;11:131-138.
    • (2001) Trends Cardiovasc Med , vol.11 , pp. 131-138
    • Colles, S.M.1    Maxson, J.M.2    Carlson, S.G.3    Chisolm, G.M.4
  • 21
    • 13544257455 scopus 로고    scopus 로고
    • Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells
    • Roussi S, Winter A, Gosse F,Werner D, Zhang X, Marchioni E et al. Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells. Cell Death Differ 2005;12: 128-135.
    • (2005) Cell Death Differ , vol.12 , pp. 128-135
    • Roussi, S.1    Winter, A.2    Gosse, F.3    Werner, D.4    Zhang, X.5    Marchioni, E.6
  • 22
    • 0034736137 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol activates a cytochrome c release-mediated caspase cascade
    • Yang L, Sinensky MS. 25-Hydroxycholesterol activates a cytochrome c release-mediated caspase cascade. Biochem Biophys Res Commun 2000;278:557-563.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 557-563
    • Yang, L.1    Sinensky, M.S.2
  • 23
    • 4444278820 scopus 로고    scopus 로고
    • 7-Ketocholesterol induces reversible cytochrome c release in smooth muscle cells in absence of mitochondrial swelling
    • Seye CI, Knaapen MW, Daret D, Desgranges C, Herman AG, Kockx MM et al. 7-Ketocholesterol induces reversible cytochrome c release in smooth muscle cells in absence of mitochondrial swelling. Cardiovasc Res 2004;64:144-153.
    • (2004) Cardiovasc Res , vol.64 , pp. 144-153
    • Seye, C.I.1    Knaapen, M.W.2    Daret, D.3    Desgranges, C.4    Herman, A.G.5    Kockx, M.M.6
  • 24
    • 78751528230 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior
    • Li Z, Ji G, Neugebauer V. Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior. J Neurosci 2011;31:1114-1127.
    • (2011) J Neurosci , vol.31 , pp. 1114-1127
    • Li, Z.1    Ji, G.2    Neugebauer, V.3
  • 25
    • 69949123810 scopus 로고    scopus 로고
    • Role PKA and p38 MAPK on ROS production in neutrophil age-related: Lack of IL-10 effect in older subjects
    • Chaves MM, Costa DC, de Oliveira BF, Rocha MI, Nogueira-Machado JA. Role PKA and p38 MAPK on ROS production in neutrophil age-related: Lack of IL-10 effect in older subjects. Mech Ageing Dev 2009;130:588-591.
    • (2009) Mech Ageing Dev , vol.130 , pp. 588-591
    • Chaves, M.M.1    Costa, D.C.2    De Oliveira, B.F.3    Rocha, M.I.4    Nogueira-Machado, J.A.5
  • 26
    • 33947169175 scopus 로고    scopus 로고
    • Protein kinase A catalytic subunit alters cardiac mitochondrial redox state and membrane potential via the formation of reactive oxygen species
    • Nagasaka S, Katoh H, Niu CF, Matsui S, Urushida T, Satoh H et al. Protein kinase A catalytic subunit alters cardiac mitochondrial redox state and membrane potential via the formation of reactive oxygen species. Circ J 2007;71:429-436.
    • (2007) Circ J , vol.71 , pp. 429-436
    • Nagasaka, S.1    Katoh, H.2    Niu, C.F.3    Matsui, S.4    Urushida, T.5    Satoh, H.6
  • 28
    • 79954497176 scopus 로고    scopus 로고
    • Deficit of complex i activity inhuman skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: Involvement of the cAMP/PKA signalling pathway
    • Valenti D,Manente GA,MoroL, Marra E, Vacca RA. Deficit of complex I activity inhuman skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway. Biochem J 2011;435:679-688.
    • (2011) Biochem J , vol.435 , pp. 679-688
    • Valenti, D.1    Manente, G.A.2    Moro, L.3    Marra, E.4    Vacca, R.A.5
  • 29
    • 33644867986 scopus 로고    scopus 로고
    • Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury
    • Prabu SK, Anandatheerthavarada HK, Raza H, Srinivasan S, Spear JF, Avadhani NG. Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury. J Biol Chem 2006;281: 2061-2070.
    • (2006) J Biol Chem , vol.281 , pp. 2061-2070
    • Prabu, S.K.1    Anandatheerthavarada, H.K.2    Raza, H.3    Srinivasan, S.4    Spear, J.F.5    Avadhani, N.G.6
  • 31
    • 84870291477 scopus 로고    scopus 로고
    • Moderate superoxide production is an early promoter of mitochondrial biogenesis in differentiating N2a neuroblastoma cells
    • Valero T, Moschopoulou G, Mayor-Lopez L, Kintzios S. Moderate superoxide production is an early promoter of mitochondrial biogenesis in differentiating N2a neuroblastoma cells. Neurochem Int 2012;61:1333-1343.
    • (2012) Neurochem Int , vol.61 , pp. 1333-1343
    • Valero, T.1    Moschopoulou, G.2    Mayor-Lopez, L.3    Kintzios, S.4
  • 32
    • 0025606328 scopus 로고
    • Type II regulatory subunit dimerization determines the subcellular localization of the cAMP-dependent protein kinase
    • Scott JD, Stofko RE, McDonald JR, Comer JD, Vitalis EA, Mangili JA. Type II regulatory subunit dimerization determines the subcellular localization of the cAMP-dependent protein kinase. J Biol Chem 1990;265:21561-21566.
    • (1990) J Biol Chem , vol.265 , pp. 21561-21566
    • Scott, J.D.1    Stofko, R.E.2    McDonald, J.R.3    Comer, J.D.4    Vitalis, E.A.5    Mangili, J.A.6
  • 33
    • 0028588997 scopus 로고
    • A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP
    • Rubin CS. A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP. Biochim Biophys Acta 1994;1224:467-479.
    • (1994) Biochim Biophys Acta , vol.1224 , pp. 467-479
    • Rubin, C.S.1
  • 34
    • 0033031288 scopus 로고    scopus 로고
    • CAMP-dependent protein kinase and phosphoproteins in mammalian mitochondria. An extension of the cAMPmediated intracellular signal transduction
    • Papa S, Sardanelli AM, Scacco S, Technikova-Dobrova Z. cAMP-dependent protein kinase and phosphoproteins in mammalian mitochondria. An extension of the cAMPmediated intracellular signal transduction. FEBS Lett 1999;444:245-249.
    • (1999) FEBS Lett , vol.444 , pp. 245-249
    • Papa, S.1    Sardanelli, A.M.2    Scacco, S.3    Technikova-Dobrova, Z.4
  • 35
    • 0035923443 scopus 로고    scopus 로고
    • Cyclic adenosine monophosphate-dependent phosphorylation of mammalian mitochondrial proteins: Enzyme and substrate characterization and functional role
    • Technikova-Dobrova Z, Sardanelli AM, Speranza F, Scacco S, Signorile A, LorussoVet al. Cyclic adenosine monophosphate-dependent phosphorylation of mammalian mitochondrial proteins: enzyme and substrate characterization and functional role. Biochemistry 2001;40:13941-13947.
    • (2001) Biochemistry , vol.40 , pp. 13941-13947
    • Technikova-Dobrova, Z.1    Sardanelli, A.M.2    Speranza, F.3    Scacco, S.4    Signorile, A.5    Lorusso, V.6
  • 36
    • 36549069198 scopus 로고    scopus 로고
    • Regulation of BAD protein by PKA, PKCdelta and phosphatases in adult rat cardiac myocytes subjected to oxidative stress
    • Cieslak D, Lazou A. Regulation of BAD protein by PKA, PKCdelta and phosphatases in adult rat cardiac myocytes subjected to oxidative stress. Mol Cells 2007;24: 224-231.
    • (2007) Mol Cells , vol.24 , pp. 224-231
    • Cieslak, D.1    Lazou, A.2
  • 37
    • 42949157936 scopus 로고    scopus 로고
    • Gene expression signatures of cAMP/protein kinase A (PKA)-promoted, mitochondrial-dependent apoptosis. Comparative analysis of wild-type and cAMP-deathless S49 lymphoma cells
    • Zhang L, Zambon AC, Vranizan K, Pothula K, Conklin BR, Insel PA. Gene expression signatures of cAMP/protein kinase A (PKA)-promoted, mitochondrial-dependent apoptosis. Comparative analysis of wild-type and cAMP-deathless S49 lymphoma cells. J Biol Chem 2008;283:4304-4313.
    • (2008) J Biol Chem , vol.283 , pp. 4304-4313
    • Zhang, L.1    Zambon, A.C.2    Vranizan, K.3    Pothula, K.4    Conklin, B.R.5    Insel, P.A.6
  • 38
    • 0033120591 scopus 로고    scopus 로고
    • Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
    • Harada H, Becknell B, Wilm M, Mann M, Huang LJ, Taylor SS et al. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol Cell 1999;3: 413-422.
    • (1999) Mol Cell , vol.3 , pp. 413-422
    • Harada, H.1    Becknell, B.2    Wilm, M.3    Mann, M.4    Huang, L.J.5    Taylor, S.S.6
  • 39
    • 7744227096 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis
    • LinsemanDA, Butts BD, PrechtTA, Phelps RA, Le SS, LaessigTAet al. Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis. J Neurosci 2004;24:9993-10002.
    • (2004) J Neurosci , vol.24 , pp. 9993-10002
    • Linseman, D.A.1    Butts, B.D.2    Precht, T.A.3    Phelps, R.A.4    Le, S.S.5    Laessig, T.A.6
  • 41
    • 33746379603 scopus 로고    scopus 로고
    • JNK-and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells
    • Kim BJ, RyuSW, Song BJ. JNK-and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. J Biol Chem 2006;281:21256-21265.
    • (2006) J Biol Chem , vol.281 , pp. 21256-21265
    • Kim, B.J.1    Ryu, S.W.2    Song, B.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.