SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: Implications for vascular aging

Biochemical Pharmacology

Volumn 85, Issue 9, 2013, Pages 1288-1296

  Zarzuelo, María José ^a   López Sepúlveda, Rocío ^a   Sánchez, Manuel ^a   Romero, Miguel ^a   Gómez Guzmán, Manuel ^a   Ungvary, Zoltan ^b   Pérez Vizcaíno, Francisco ^c   Jiménez, Rosario ^a   Duarte, Juan ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Endothelial dysfunction; NADPH oxidase; PPAR ; SIRT1

Indexed keywords

ACETYLCHOLINE; APOCYNIN; CALCIMYCIN; ENZYME INHIBITOR; EX 527; MESSENGER RNA; NICOTINAMIDE; NITROUS OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; RESVERATROL; SIRTINOL; SIRTUIN 1; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ACETYLATION; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL WALL; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SUBUNIT; RAT; UPREGULATION; WISTAR RAT;

ACETYLATION; AGING; ANIMALS; AORTA, THORACIC; CAVEOLINS; CYCLIC GMP; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; MALE; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PPAR ALPHA; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SIRTUIN 1; STILBENES; TRANSCRIPTION FACTORS; VASODILATION; VASODILATOR AGENTS;

EID: 84875727264     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.02.015     Document Type: Article

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