메뉴 건너뛰기




Volumn 40, Issue 3, 2016, Pages 138-151

Stem cell-based therapies for the newborn lung and brain: Possibilities and challenges

Author keywords

Bronchopulmonary dysplasia; Exosomes; Hypoxic ischemic encephalopaty; Mesenchymal stem cells

Indexed keywords

ADIPOCYTE; AMNION CELL; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; COLONY FORMING CELL; CORD BLOOD STEM CELL TRANSPLANTATION; DISEASE EXACERBATION; EMBRYONIC STEM CELL; ENCEPHALOMALACIA; EXOSOME; GENETIC MANIPULATION; GESTATIONAL AGE; HUMAN; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IN VITRO STUDY; IN VIVO STUDY; LUNG DYSPLASIA; MESENCHYMAL STEM CELL TRANSPLANTATION; MULTICENTER STUDY (TOPIC); NEWBORN MORBIDITY; NONHUMAN; NUCLEAR REPROGRAMMING; OLIGODENDROGLIA; OPEN STUDY; OSTEOBLAST; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PREMATURITY; PRIORITY JOURNAL; PROTEOMICS; RECURRENT DISEASE; REVIEW; RISK FACTOR; TH17 CELL; TH2 CELL; ADVERSE DRUG REACTION; ADVERSE EFFECTS; BRONCHOPULMONARY DYSPLASIA; CLASSIFICATION; HYPOXIA-ISCHEMIA, BRAIN; METABOLISM; NEWBORN; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; STEM CELL; STEM CELL TRANSPLANTATION; THEORETICAL MODEL; TREATMENT OUTCOME; VERY LOW BIRTH WEIGHT;

EID: 84954306749     PISSN: 01460005     EISSN: 1558075X     Source Type: Journal    
DOI: 10.1053/j.semperi.2015.12.002     Document Type: Review
Times cited : (62)

References (150)
  • 1
    • 84941702065 scopus 로고    scopus 로고
    • Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012
    • Stoll B.J., Hansen N.I., Bell E.F., et al. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012. J Am Med Assoc 2015, 314(10):1039-1051.
    • (2015) J Am Med Assoc , vol.314 , Issue.10 , pp. 1039-1051
    • Stoll, B.J.1    Hansen, N.I.2    Bell, E.F.3
  • 2
    • 0014208018 scopus 로고
    • Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia
    • Northway W.H., Rosan R.C., Porter D.Y. Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia. N Engl J Med 1967, 276(7):357-368.
    • (1967) N Engl J Med , vol.276 , Issue.7 , pp. 357-368
    • Northway, W.H.1    Rosan, R.C.2    Porter, D.Y.3
  • 3
    • 36849067910 scopus 로고    scopus 로고
    • Pulmonary artery hypertension in formerly premature infants with bronchopulmonary dysplasia: clinical features and outcomes in the surfactant era
    • Khemani E., McElhinney D.B., Rhein L., et al. Pulmonary artery hypertension in formerly premature infants with bronchopulmonary dysplasia: clinical features and outcomes in the surfactant era. Pediatrics 2007, 120(6):1260-1269.
    • (2007) Pediatrics , vol.120 , Issue.6 , pp. 1260-1269
    • Khemani, E.1    McElhinney, D.B.2    Rhein, L.3
  • 4
    • 84890567900 scopus 로고    scopus 로고
    • Pulmonary hypertension in bronchopulmonary dysplasia: clinical findings, cardiovascular anomalies and outcomes
    • del Cerro M.J., Sabate Rotes A., Carton A., et al. Pulmonary hypertension in bronchopulmonary dysplasia: clinical findings, cardiovascular anomalies and outcomes. Pediatr Pulmonol 2014, 49(1):49-59.
    • (2014) Pediatr Pulmonol , vol.49 , Issue.1 , pp. 49-59
    • del Cerro, M.J.1    Sabate Rotes, A.2    Carton, A.3
  • 5
    • 84944463128 scopus 로고    scopus 로고
    • Early inhaled budesonide for the prevention of bronchopulmonary dysplasia
    • Bassler D., Plavka R., Shinwell E.S., et al. Early inhaled budesonide for the prevention of bronchopulmonary dysplasia. N Engl J Med 2015, 373(16):1497-1506.
    • (2015) N Engl J Med , vol.373 , Issue.16 , pp. 1497-1506
    • Bassler, D.1    Plavka, R.2    Shinwell, E.S.3
  • 6
    • 77954315863 scopus 로고    scopus 로고
    • Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy
    • Kurinczuk J.J., White-Koning M., Badawi N. Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy. Early Hum Dev 2010, 86(6):329-338.
    • (2010) Early Hum Dev , vol.86 , Issue.6 , pp. 329-338
    • Kurinczuk, J.J.1    White-Koning, M.2    Badawi, N.3
  • 7
    • 26444452073 scopus 로고    scopus 로고
    • Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy
    • Shankaran S., Laptook A.R., Ehrenkranz R.A., et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 2005, 353(15):1574-1584.
    • (2005) N Engl J Med , vol.353 , Issue.15 , pp. 1574-1584
    • Shankaran, S.1    Laptook, A.R.2    Ehrenkranz, R.A.3
  • 8
    • 84864148261 scopus 로고    scopus 로고
    • Cord blood angiogenic progenitor cells are decreased in bronchopulmonary dysplasia
    • Baker C.D., Balasubramaniam V., Mourani P.M., et al. Cord blood angiogenic progenitor cells are decreased in bronchopulmonary dysplasia. Eur Respir J 2012, 40(6):1516-1522.
    • (2012) Eur Respir J , vol.40 , Issue.6 , pp. 1516-1522
    • Baker, C.D.1    Balasubramaniam, V.2    Mourani, P.M.3
  • 9
    • 69949110938 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells in preterm infants with bronchopulmonary dysplasia
    • Borghesi A., Massa M., Campanelli R., et al. Circulating endothelial progenitor cells in preterm infants with bronchopulmonary dysplasia. Am J Respir Crit Care Med 2009, 180(6):540-546.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.6 , pp. 540-546
    • Borghesi, A.1    Massa, M.2    Campanelli, R.3
  • 10
    • 78049437518 scopus 로고    scopus 로고
    • Isolation of tracheal aspirate mesenchymal stromal cells predicts bronchopulmonary dysplasia
    • Popova A.P., Bozyk P.D., Bentley J.K., et al. Isolation of tracheal aspirate mesenchymal stromal cells predicts bronchopulmonary dysplasia. Pediatrics 2010, 126(5):e1127-e1133.
    • (2010) Pediatrics , vol.126 , Issue.5 , pp. e1127-e1133
    • Popova, A.P.1    Bozyk, P.D.2    Bentley, J.K.3
  • 11
    • 84857095253 scopus 로고    scopus 로고
    • Mesenchymal stromal cells from neonatal tracheal aspirates demonstrate a pattern of lung-specific gene expression
    • Bozyk P.D., Popova A.P., Bentley J.K., et al. Mesenchymal stromal cells from neonatal tracheal aspirates demonstrate a pattern of lung-specific gene expression. Stem Cells Dev 2011, 20(11):1995-2007.
    • (2011) Stem Cells Dev , vol.20 , Issue.11 , pp. 1995-2007
    • Bozyk, P.D.1    Popova, A.P.2    Bentley, J.K.3
  • 12
    • 41449091346 scopus 로고    scopus 로고
    • Pathogenesis of cerebral white matter injury of prematurity
    • Khwaja O., Volpe J.J. Pathogenesis of cerebral white matter injury of prematurity. Arch Dis Child Fetal Neonatal Ed 2008, 93(2):F153-F161.
    • (2008) Arch Dis Child Fetal Neonatal Ed , vol.93 , Issue.2 , pp. F153-F161
    • Khwaja, O.1    Volpe, J.J.2
  • 13
    • 27644457450 scopus 로고    scopus 로고
    • Mesenchymal stem cells from human bone marrow and adipose tissue: isolation, characterization, and differentiation potentialities
    • Romanov Y.A., Darevskaya A.N., Merzlikina N.V., Buravkova L.B. Mesenchymal stem cells from human bone marrow and adipose tissue: isolation, characterization, and differentiation potentialities. Bull Exp Biol Med 2005, 140(1):138-143.
    • (2005) Bull Exp Biol Med , vol.140 , Issue.1 , pp. 138-143
    • Romanov, Y.A.1    Darevskaya, A.N.2    Merzlikina, N.V.3    Buravkova, L.B.4
  • 14
    • 0037240649 scopus 로고    scopus 로고
    • Searching for alternative sources of postnatal human mesenchymal stem cells: candidate msc-like cells from umbilical cord
    • Romanov Y.A., Svintsitskaya V.A., Smirnov V.N. Searching for alternative sources of postnatal human mesenchymal stem cells: candidate msc-like cells from umbilical cord. Stem Cells 2003, 21(1):105-110.
    • (2003) Stem Cells , vol.21 , Issue.1 , pp. 105-110
    • Romanov, Y.A.1    Svintsitskaya, V.A.2    Smirnov, V.N.3
  • 15
    • 38349052370 scopus 로고    scopus 로고
    • Multipotent stem cells from umbilical cord: cord is richer than blood!
    • Secco M., Zucconi E., Vieira N.M., et al. Multipotent stem cells from umbilical cord: cord is richer than blood!. Stem Cells 2008, 26(1):146-150.
    • (2008) Stem Cells , vol.26 , Issue.1 , pp. 146-150
    • Secco, M.1    Zucconi, E.2    Vieira, N.M.3
  • 16
    • 23644440056 scopus 로고    scopus 로고
    • Comparison of mesenchymal stem cells obtained from different human tissues
    • Musina R.A., Bekchanova E.S., Sukhikh G.T. Comparison of mesenchymal stem cells obtained from different human tissues. Bull Exp Biol Med 2005, 139(4):504-509.
    • (2005) Bull Exp Biol Med , vol.139 , Issue.4 , pp. 504-509
    • Musina, R.A.1    Bekchanova, E.S.2    Sukhikh, G.T.3
  • 17
    • 51849091575 scopus 로고    scopus 로고
    • Comparative analysis of mesenchymal stem cells from bone marrow, cartilage, and adipose tissue
    • Peng L., Jia Z., Yin X., et al. Comparative analysis of mesenchymal stem cells from bone marrow, cartilage, and adipose tissue. Stem Cells Dev 2008, 17(4):761-773.
    • (2008) Stem Cells Dev , vol.17 , Issue.4 , pp. 761-773
    • Peng, L.1    Jia, Z.2    Yin, X.3
  • 18
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement
    • Dominici M., Le Blanc K., Mueller I., et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement. Cytotherapy 2006, 8(4):315-317.
    • (2006) Cytotherapy , vol.8 , Issue.4 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3
  • 19
    • 84928724209 scopus 로고    scopus 로고
    • An official american thoracic society workshop report: stem cells and cell therapies in lung biology and diseases
    • Weiss D.J., Chambers D., Giangreco A., et al. An official american thoracic society workshop report: stem cells and cell therapies in lung biology and diseases. Ann Am Thorac Soc 2015, 12(4):S79-S97.
    • (2015) Ann Am Thorac Soc , vol.12 , Issue.4 , pp. S79-S97
    • Weiss, D.J.1    Chambers, D.2    Giangreco, A.3
  • 20
    • 56149111927 scopus 로고    scopus 로고
    • Lung resident mesenchymal stem cells isolated from human lung allografts inhibit T cell proliferation via a soluble mediator
    • Jarvinen L., Badri L., Wettlaufer S., et al. Lung resident mesenchymal stem cells isolated from human lung allografts inhibit T cell proliferation via a soluble mediator. J Immunol 2008, 181(6):4389-4396.
    • (2008) J Immunol , vol.181 , Issue.6 , pp. 4389-4396
    • Jarvinen, L.1    Badri, L.2    Wettlaufer, S.3
  • 21
    • 84862645100 scopus 로고    scopus 로고
    • Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease
    • van Koppen A., Joles J.A., van Balkom B.W., et al. Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease. PLoS One 2012, 7(6):e38746.
    • (2012) PLoS One , vol.7 , Issue.6 , pp. e38746
    • van Koppen, A.1    Joles, J.A.2    van Balkom, B.W.3
  • 22
    • 70450180838 scopus 로고    scopus 로고
    • Harvesting human adipose tissue-derived adult stem cells: resection versus liposuction
    • Schreml S., Babilas P., Fruth S., et al. Harvesting human adipose tissue-derived adult stem cells: resection versus liposuction. Cytotherapy 2009, 11(7):947-957.
    • (2009) Cytotherapy , vol.11 , Issue.7 , pp. 947-957
    • Schreml, S.1    Babilas, P.2    Fruth, S.3
  • 23
    • 84871386469 scopus 로고    scopus 로고
    • Toward personalized cell therapies by using stem cells: seven relevant topics for safety and success in stem cell therapy
    • de Sa Silva F., Almeida P.N., Rettore J.V., et al. Toward personalized cell therapies by using stem cells: seven relevant topics for safety and success in stem cell therapy. J Biomed Biotechnol 2012, 2012:758102.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 758102
    • de Sa Silva, F.1    Almeida, P.N.2    Rettore, J.V.3
  • 24
    • 17444379357 scopus 로고    scopus 로고
    • Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation
    • Le Blanc K., Ringden O. Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2005, 11(5):321-334.
    • (2005) Biol Blood Marrow Transplant , vol.11 , Issue.5 , pp. 321-334
    • Le Blanc, K.1    Ringden, O.2
  • 25
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness
    • Beyth S., Borovsky Z., Mevorach D., et al. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood 2005, 105(5):2214-2219.
    • (2005) Blood , vol.105 , Issue.5 , pp. 2214-2219
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3
  • 27
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: evidence that activated nk cells are capable of killing mscs, whereas mscs can inhibit il-2-induced nk-cell proliferation
    • Spaggiari G.M., Capobianco A., Becchetti S., Mingari M.C., Moretta L. Mesenchymal stem cell-natural killer cell interactions: evidence that activated nk cells are capable of killing mscs, whereas mscs can inhibit il-2-induced nk-cell proliferation. Blood 2006, 107(4):1484-1490.
    • (2006) Blood , vol.107 , Issue.4 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 28
    • 77950617181 scopus 로고    scopus 로고
    • Functional differences between mesenchymal stem cell populations are reflected by their transcriptome
    • Jansen B.J., Gilissen C., Roelofs H., et al. Functional differences between mesenchymal stem cell populations are reflected by their transcriptome. Stem Cells Dev 2010, 19(4):481-490.
    • (2010) Stem Cells Dev , vol.19 , Issue.4 , pp. 481-490
    • Jansen, B.J.1    Gilissen, C.2    Roelofs, H.3
  • 30
    • 35348861286 scopus 로고    scopus 로고
    • Functional network analysis of the transcriptomes of mesenchymal stem cells derived from amniotic fluid, amniotic membrane, cord blood, and bone marrow
    • Tsai M.S., Hwang S.M., Chen K.D., et al. Functional network analysis of the transcriptomes of mesenchymal stem cells derived from amniotic fluid, amniotic membrane, cord blood, and bone marrow. Stem Cells 2007, 25(10):2511-2523.
    • (2007) Stem Cells , vol.25 , Issue.10 , pp. 2511-2523
    • Tsai, M.S.1    Hwang, S.M.2    Chen, K.D.3
  • 31
    • 84871986194 scopus 로고    scopus 로고
    • Stability of human mesenchymal stem cells during in vitro culture: considerations for cell therapy
    • Binato R., de Souza Fernandez T., Lazzarotto-Silva C., et al. Stability of human mesenchymal stem cells during in vitro culture: considerations for cell therapy. Cell Prolif 2013, 46(1):10-22.
    • (2013) Cell Prolif , vol.46 , Issue.1 , pp. 10-22
    • Binato, R.1    de Souza Fernandez, T.2    Lazzarotto-Silva, C.3
  • 32
    • 77950899350 scopus 로고    scopus 로고
    • Monitoring the genomic stability of in vitro cultured rat bone-marrow-derived mesenchymal stem cells
    • Foudah D., Redaelli S., Donzelli E., et al. Monitoring the genomic stability of in vitro cultured rat bone-marrow-derived mesenchymal stem cells. Chromosome Res 2009, 17(8):1025-1039.
    • (2009) Chromosome Res , vol.17 , Issue.8 , pp. 1025-1039
    • Foudah, D.1    Redaelli, S.2    Donzelli, E.3
  • 33
    • 33845341472 scopus 로고    scopus 로고
    • Spontaneous transformation of cultured mouse bone marrow-derived stromal cells
    • Zhou Y.F., Bosch-Marce M., Okuyama H., et al. Spontaneous transformation of cultured mouse bone marrow-derived stromal cells. Cancer Res 2006, 66(22):10849-10854.
    • (2006) Cancer Res , vol.66 , Issue.22 , pp. 10849-10854
    • Zhou, Y.F.1    Bosch-Marce, M.2    Okuyama, H.3
  • 34
    • 70449686885 scopus 로고    scopus 로고
    • Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease
    • Aslam M., Baveja R., Liang O.D., et al. Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease. Am J Respir Crit Care Med 2009, 180(11):1122-1130.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.11 , pp. 1122-1130
    • Aslam, M.1    Baveja, R.2    Liang, O.D.3
  • 35
    • 84863012337 scopus 로고    scopus 로고
    • Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells dose-dependently attenuates hyperoxia-induced lung injury in neonatal rats
    • Chang Y.S., Choi S.J., Sung D.K., et al. Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells dose-dependently attenuates hyperoxia-induced lung injury in neonatal rats. Cell Transplant 2011, 20(11-12):1843-1854.
    • (2011) Cell Transplant , vol.20 , Issue.11-12 , pp. 1843-1854
    • Chang, Y.S.1    Choi, S.J.2    Sung, D.K.3
  • 36
    • 70449671455 scopus 로고    scopus 로고
    • Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats
    • van Haaften T., Byrne R., Bonnet S., et al. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med 2009, 180(11):1131-1142.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.11 , pp. 1131-1142
    • van Haaften, T.1    Byrne, R.2    Bonnet, S.3
  • 37
    • 84872086190 scopus 로고    scopus 로고
    • Long-term reparative effects of mesenchymal stem cell therapy following neonatal hyperoxia-induced lung injury
    • Sutsko R.P., Young K.C., Ribeiro A., et al. Long-term reparative effects of mesenchymal stem cell therapy following neonatal hyperoxia-induced lung injury. Pediatr Res 2013, 73(1):46-53.
    • (2013) Pediatr Res , vol.73 , Issue.1 , pp. 46-53
    • Sutsko, R.P.1    Young, K.C.2    Ribeiro, A.3
  • 38
    • 84862495707 scopus 로고    scopus 로고
    • Role of bone marrow-derived mesenchymal stem cells in the prevention of hyperoxia-induced lung injury in newborn mice
    • Zhang X., Wang H., Shi Y., et al. Role of bone marrow-derived mesenchymal stem cells in the prevention of hyperoxia-induced lung injury in newborn mice. Cell Biol Int 2012, 36(6):589-594.
    • (2012) Cell Biol Int , vol.36 , Issue.6 , pp. 589-594
    • Zhang, X.1    Wang, H.2    Shi, Y.3
  • 39
    • 72049118713 scopus 로고    scopus 로고
    • Human umbilical cord blood-derived mesenchymal stem cells attenuate hyperoxia-induced lung injury in neonatal rats
    • Chang Y.S., Oh W., Choi S.J., et al. Human umbilical cord blood-derived mesenchymal stem cells attenuate hyperoxia-induced lung injury in neonatal rats. Cell Transplant 2009, 18(8):869-886.
    • (2009) Cell Transplant , vol.18 , Issue.8 , pp. 869-886
    • Chang, Y.S.1    Oh, W.2    Choi, S.J.3
  • 40
    • 84876286103 scopus 로고    scopus 로고
    • Short-term, long-term and paracrine effect of human umbilical cord-derived stem cells in lung injury prevention and repair in experimental bronchopulmonary dysplasia
    • Pierro M., Ionescu L., Montemurro T., et al. Short-term, long-term and paracrine effect of human umbilical cord-derived stem cells in lung injury prevention and repair in experimental bronchopulmonary dysplasia. Thorax 2013, 68(5):475-484.
    • (2013) Thorax , vol.68 , Issue.5 , pp. 475-484
    • Pierro, M.1    Ionescu, L.2    Montemurro, T.3
  • 41
    • 84872673125 scopus 로고    scopus 로고
    • Timing of umbilical cord blood derived mesenchymal stem cells transplantation determines therapeutic efficacy in the neonatal hyperoxic lung injury
    • Chang Y.S., Choi S.J., Ahn S.Y., et al. Timing of umbilical cord blood derived mesenchymal stem cells transplantation determines therapeutic efficacy in the neonatal hyperoxic lung injury. PLoS One 2013, 8(1):e52419.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e52419
    • Chang, Y.S.1    Choi, S.J.2    Ahn, S.Y.3
  • 42
    • 84870241134 scopus 로고    scopus 로고
    • Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension
    • Hansmann G., Fernandez-Gonzalez A., Aslam M., et al. Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension. Pulm Circ 2012, 2(2):170-181.
    • (2012) Pulm Circ , vol.2 , Issue.2 , pp. 170-181
    • Hansmann, G.1    Fernandez-Gonzalez, A.2    Aslam, M.3
  • 43
    • 84860654915 scopus 로고    scopus 로고
    • Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury
    • Islam M.N., Das S.R., Emin M.T., et al. Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury. Nat Med 2012, 18(5):759-765.
    • (2012) Nat Med , vol.18 , Issue.5 , pp. 759-765
    • Islam, M.N.1    Das, S.R.2    Emin, M.T.3
  • 44
    • 44349134076 scopus 로고    scopus 로고
    • Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium
    • Timmers L., Lim S.K., Arslan F., et al. Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium. Stem Cell Res 2007, 1(2):129-137.
    • (2007) Stem Cell Res , vol.1 , Issue.2 , pp. 129-137
    • Timmers, L.1    Lim, S.K.2    Arslan, F.3
  • 45
    • 4143128861 scopus 로고    scopus 로고
    • Bone-marrow-derived cells for enhancing collateral development: mechanisms, animal data, and initial clinical experiences
    • Kinnaird T., Stabile E., Burnett M.S., Epstein S.E. Bone-marrow-derived cells for enhancing collateral development: mechanisms, animal data, and initial clinical experiences. Circ Res 2004, 95(4):354-363.
    • (2004) Circ Res , vol.95 , Issue.4 , pp. 354-363
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Epstein, S.E.4
  • 46
    • 84876881547 scopus 로고    scopus 로고
    • Regenerating the injured kidney with human umbilical cord mesenchymal stem cell-derived exosomes
    • Dorronsoro A., Robbins P.D. Regenerating the injured kidney with human umbilical cord mesenchymal stem cell-derived exosomes. Stem Cell Res Ther 2013, 4(2):39.
    • (2013) Stem Cell Res Ther , vol.4 , Issue.2 , pp. 39
    • Dorronsoro, A.1    Robbins, P.D.2
  • 48
    • 4444226979 scopus 로고    scopus 로고
    • Identification and proteomic profiling of exosomes in human urine
    • Pisitkun T., Shen R.F., Knepper M.A. Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci U S A 2004, 101(36):13368-13373.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.36 , pp. 13368-13373
    • Pisitkun, T.1    Shen, R.F.2    Knepper, M.A.3
  • 49
    • 84859515309 scopus 로고    scopus 로고
    • The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities
    • Pant S., Hilton H., Burczynski M.E. The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities. Biochem Pharmacol 2012, 83(11):1484-1494.
    • (2012) Biochem Pharmacol , vol.83 , Issue.11 , pp. 1484-1494
    • Pant, S.1    Hilton, H.2    Burczynski, M.E.3
  • 50
    • 79953202918 scopus 로고    scopus 로고
    • Exosome target cell selection and the importance of exosomal tetraspanins: a hypothesis
    • Rana S., Zoller M. Exosome target cell selection and the importance of exosomal tetraspanins: a hypothesis. Biochem Soc Trans 2011, 39(2):559-562.
    • (2011) Biochem Soc Trans , vol.39 , Issue.2 , pp. 559-562
    • Rana, S.1    Zoller, M.2
  • 51
    • 79953858598 scopus 로고    scopus 로고
    • Delivery of sirna to the mouse brain by systemic injection of targeted exosomes
    • Alvarez-Erviti L., Seow Y., Yin H., Betts C., Lakhal S., Wood M.J. Delivery of sirna to the mouse brain by systemic injection of targeted exosomes. Nat Biotechnol 2011, 29(4):341-345.
    • (2011) Nat Biotechnol , vol.29 , Issue.4 , pp. 341-345
    • Alvarez-Erviti, L.1    Seow, Y.2    Yin, H.3    Betts, C.4    Lakhal, S.5    Wood, M.J.6
  • 52
    • 84945306718 scopus 로고    scopus 로고
    • Systemic administration of human bone marrow-derived mesenchymal stromal cell extracellular vesicles ameliorates aspergillus hyphal extract-induced allergic airway inflammation in immunocompetent mice
    • Cruz F.F., Borg Z.D., Goodwin M., et al. Systemic administration of human bone marrow-derived mesenchymal stromal cell extracellular vesicles ameliorates aspergillus hyphal extract-induced allergic airway inflammation in immunocompetent mice. Stem Cells Transl Med 2015, 4(11):1302-1316.
    • (2015) Stem Cells Transl Med , vol.4 , Issue.11 , pp. 1302-1316
    • Cruz, F.F.1    Borg, Z.D.2    Goodwin, M.3
  • 53
    • 84942855979 scopus 로고    scopus 로고
    • Optimal route for human umbilical cord blood-derived mesenchymal stem cell transplantation to protect against neonatal hyperoxic lung injury: gene expression profiles and histopathology
    • Sung D.K., Chang Y.S., Ahn S.Y., et al. Optimal route for human umbilical cord blood-derived mesenchymal stem cell transplantation to protect against neonatal hyperoxic lung injury: gene expression profiles and histopathology. PLoS One 2015, 10(8):e0135574.
    • (2015) PLoS One , vol.10 , Issue.8 , pp. e0135574
    • Sung, D.K.1    Chang, Y.S.2    Ahn, S.Y.3
  • 54
    • 84900811078 scopus 로고    scopus 로고
    • Intravenous and intratracheal mesenchymal stromal cell injection in a mouse model of pulmonary emphysema
    • Tibboel J., Keijzer R., Reiss I., de Jongste J.C., Post M. Intravenous and intratracheal mesenchymal stromal cell injection in a mouse model of pulmonary emphysema. COPD 2014, 11(3):310-318.
    • (2014) COPD , vol.11 , Issue.3 , pp. 310-318
    • Tibboel, J.1    Keijzer, R.2    Reiss, I.3    de Jongste, J.C.4    Post, M.5
  • 55
    • 0035891595 scopus 로고    scopus 로고
    • Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia
    • Bhatt A.J., Pryhuber G.S., Huyck H., Watkins R.H., Metlay L.A., Maniscalco W.M. Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001, 164(10 Pt 1):1971-1980.
    • (2001) Am J Respir Crit Care Med , vol.164 , Issue.10 , pp. 1971-1980
    • Bhatt, A.J.1    Pryhuber, G.S.2    Huyck, H.3    Watkins, R.H.4    Metlay, L.A.5    Maniscalco, W.M.6
  • 56
    • 27144509839 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization
    • Thebaud B., Ladha F., Michelakis E.D., et al. Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization. Circulation 2005, 112(16):2477-2486.
    • (2005) Circulation , vol.112 , Issue.16 , pp. 2477-2486
    • Thebaud, B.1    Ladha, F.2    Michelakis, E.D.3
  • 57
    • 0031019745 scopus 로고    scopus 로고
    • Isolation of putative progenitor endothelial cells for angiogenesis
    • Asahara T., Murohara T., Sullivan A., et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997, 275(5302):964-967.
    • (1997) Science , vol.275 , Issue.5302 , pp. 964-967
    • Asahara, T.1    Murohara, T.2    Sullivan, A.3
  • 58
    • 7244242362 scopus 로고    scopus 로고
    • Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood
    • Ingram D.A., Mead L.E., Tanaka H., et al. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 2004, 104(9):2752-2760.
    • (2004) Blood , vol.104 , Issue.9 , pp. 2752-2760
    • Ingram, D.A.1    Mead, L.E.2    Tanaka, H.3
  • 59
    • 33847348148 scopus 로고    scopus 로고
    • Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals
    • Yoder M.C., Mead L.E., Prater D., et al. Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood 2007, 109(5):1801-1809.
    • (2007) Blood , vol.109 , Issue.5 , pp. 1801-1809
    • Yoder, M.C.1    Mead, L.E.2    Prater, D.3
  • 60
    • 77249157301 scopus 로고    scopus 로고
    • Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice
    • Balasubramaniam V., Ryan S.L., Seedorf G.J., et al. Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice. Am J Physiol Lung Cell Mol Physiol 2010, 298(3):L315-L323.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , Issue.3 , pp. L315-L323
    • Balasubramaniam, V.1    Ryan, S.L.2    Seedorf, G.J.3
  • 61
    • 84879578308 scopus 로고    scopus 로고
    • Endothelial colony-forming cell conditioned media promote angiogenesis in vitro and prevent pulmonary hypertension in experimental bronchopulmonary dysplasia
    • Baker C.D., Seedorf G.J., Wisniewski B.L., et al. Endothelial colony-forming cell conditioned media promote angiogenesis in vitro and prevent pulmonary hypertension in experimental bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 2013, 305(1):L73-L81.
    • (2013) Am J Physiol Lung Cell Mol Physiol , vol.305 , Issue.1 , pp. L73-L81
    • Baker, C.D.1    Seedorf, G.J.2    Wisniewski, B.L.3
  • 62
    • 84901427745 scopus 로고    scopus 로고
    • Existence, functional impairment, and lung repair potential of endothelial colony-forming cells in oxygen-induced arrested alveolar growth
    • Alphonse R.S., Vadivel A., Fung M., et al. Existence, functional impairment, and lung repair potential of endothelial colony-forming cells in oxygen-induced arrested alveolar growth. Circulation 2014, 129(21):2144-2157.
    • (2014) Circulation , vol.129 , Issue.21 , pp. 2144-2157
    • Alphonse, R.S.1    Vadivel, A.2    Fung, M.3
  • 63
    • 34547862225 scopus 로고    scopus 로고
    • Stem cells derived from human fetal membranes display multilineage differentiation potential
    • Ilancheran S., Michalska A., Peh G., Wallace E.M., Pera M., Manuelpillai U. Stem cells derived from human fetal membranes display multilineage differentiation potential. Biol Reprod 2007, 77(3):577-588.
    • (2007) Biol Reprod , vol.77 , Issue.3 , pp. 577-588
    • Ilancheran, S.1    Michalska, A.2    Peh, G.3    Wallace, E.M.4    Pera, M.5    Manuelpillai, U.6
  • 64
    • 77957701000 scopus 로고    scopus 로고
    • Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair
    • Moodley Y., Ilancheran S., Samuel C., et al. Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair. Am J Respir Crit Care Med 2010, 182(5):643-651.
    • (2010) Am J Respir Crit Care Med , vol.182 , Issue.5 , pp. 643-651
    • Moodley, Y.1    Ilancheran, S.2    Samuel, C.3
  • 65
    • 79960921035 scopus 로고    scopus 로고
    • Human amnion epithelial cells as a treatment for inflammation-induced fetal lung injury in sheep
    • Vosdoganes P., Hodges R.J., Lim R., et al. Human amnion epithelial cells as a treatment for inflammation-induced fetal lung injury in sheep. Am J Obstet Gynecol 2011, 205(2):156.e126-156.e133.
    • (2011) Am J Obstet Gynecol , vol.205 , Issue.2 , pp. 156.e126-156.e133
    • Vosdoganes, P.1    Hodges, R.J.2    Lim, R.3
  • 66
    • 84864303144 scopus 로고    scopus 로고
    • Human amnion epithelial cells reduce ventilation-induced preterm lung injury in fetal sheep
    • Hodges R.J., Jenkin G., Hooper S.B., et al. Human amnion epithelial cells reduce ventilation-induced preterm lung injury in fetal sheep. Am J Obstet Gynecol 2012, 206(5):448.e8-448.e15.
    • (2012) Am J Obstet Gynecol , vol.206 , Issue.5 , pp. 448.e8-448.e15
    • Hodges, R.J.1    Jenkin, G.2    Hooper, S.B.3
  • 67
    • 84925024397 scopus 로고    scopus 로고
    • Stem cell experiments moves into clinic: new hope for children with bronchopulmonary dysplasia
    • Pawelec K., Gladysz D., Demkow U., Boruczkowski D. Stem cell experiments moves into clinic: new hope for children with bronchopulmonary dysplasia. Adv Exp Med Biol 2015, 839:47-53.
    • (2015) Adv Exp Med Biol , vol.839 , pp. 47-53
    • Pawelec, K.1    Gladysz, D.2    Demkow, U.3    Boruczkowski, D.4
  • 68
    • 84910119440 scopus 로고    scopus 로고
    • Msc microvesicles for the treatment of lung disease: a new paradigm for cell-free therapy
    • Sdrimas K., Kourembanas S. Msc microvesicles for the treatment of lung disease: a new paradigm for cell-free therapy. Antioxid Redox Signal 2014, 21(13):1905-1915.
    • (2014) Antioxid Redox Signal , vol.21 , Issue.13 , pp. 1905-1915
    • Sdrimas, K.1    Kourembanas, S.2
  • 69
    • 84892152478 scopus 로고    scopus 로고
    • Stem cells, cell therapies, and bioengineering in lung biology and diseases. Comprehensive review of the recent literature 2010-2012
    • Weiss D.J. Stem cells, cell therapies, and bioengineering in lung biology and diseases. Comprehensive review of the recent literature 2010-2012. Ann Am Thorac Soc 2013, 10(5):S45-S97.
    • (2013) Ann Am Thorac Soc , vol.10 , Issue.5 , pp. S45-S97
    • Weiss, D.J.1
  • 70
    • 84874045371 scopus 로고    scopus 로고
    • Stem cells of the adult lung: their development and role in homeostasis, regeneration, and disease
    • Wansleeben C., Barkauskas C.E., Rock J.R., Hogan B.L. Stem cells of the adult lung: their development and role in homeostasis, regeneration, and disease. Wiley Interdiscip Rev Dev Biol 2013, 2(1):131-148.
    • (2013) Wiley Interdiscip Rev Dev Biol , vol.2 , Issue.1 , pp. 131-148
    • Wansleeben, C.1    Barkauskas, C.E.2    Rock, J.R.3    Hogan, B.L.4
  • 71
    • 84901018696 scopus 로고    scopus 로고
    • Stem cell therapy for neonatal diseases associated with preterm birth
    • Borghesi A., Cova C., Gazzolo D., Stronati M. Stem cell therapy for neonatal diseases associated with preterm birth. J Clin Neonatol 2013, 2(1):1-7.
    • (2013) J Clin Neonatol , vol.2 , Issue.1 , pp. 1-7
    • Borghesi, A.1    Cova, C.2    Gazzolo, D.3    Stronati, M.4
  • 72
    • 84893516245 scopus 로고    scopus 로고
    • Stem cell-based therapy for neonatal lung disease: it is in the juice
    • Fung M.E., Thebaud B. Stem cell-based therapy for neonatal lung disease: it is in the juice. Pediatr Res 2014, 75(1-1):2-7.
    • (2014) Pediatr Res , vol.75 , Issue.1 , pp. 2-7
    • Fung, M.E.1    Thebaud, B.2
  • 73
    • 84879463046 scopus 로고    scopus 로고
    • The potential for resident lung mesenchymal stem cells to promote functional tissue regeneration: understanding microenvironmental cues
    • Foronjy R.F., Majka S.M. The potential for resident lung mesenchymal stem cells to promote functional tissue regeneration: understanding microenvironmental cues. Cells 2012, 1(4):874.
    • (2012) Cells , vol.1 , Issue.4 , pp. 874
    • Foronjy, R.F.1    Majka, S.M.2
  • 74
    • 79953787534 scopus 로고    scopus 로고
    • The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation
    • Jun D., Garat C., West J., et al. The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation. Stem Cells 2011, 29(4):725-735.
    • (2011) Stem Cells , vol.29 , Issue.4 , pp. 725-735
    • Jun, D.1    Garat, C.2    West, J.3
  • 75
    • 84890032027 scopus 로고    scopus 로고
    • Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling
    • Chow K., Fessel J.P., Kaoriihida S., et al. Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling. Pulm Circ 2013, 3(1):31-49.
    • (2013) Pulm Circ , vol.3 , Issue.1 , pp. 31-49
    • Chow, K.1    Fessel, J.P.2    Kaoriihida, S.3
  • 76
    • 84865764313 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 beta/beta-catenin signaling regulates neonatal lung mesenchymal stromal cell myofibroblastic differentiation
    • Popova A.P., Bentley J.K., Anyanwu A.C., et al. Glycogen synthase kinase-3 beta/beta-catenin signaling regulates neonatal lung mesenchymal stromal cell myofibroblastic differentiation. Am J Physiol Lung Cell Mol Physiol 2012, 303(5):L439-L448.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.303 , Issue.5 , pp. L439-L448
    • Popova, A.P.1    Bentley, J.K.2    Anyanwu, A.C.3
  • 77
    • 84860511591 scopus 로고    scopus 로고
    • Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia
    • Tropea K.A., Leder E., Aslam M., et al. Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 2012, 302(9):L829-L837.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.302 , Issue.9 , pp. L829-L837
    • Tropea, K.A.1    Leder, E.2    Aslam, M.3
  • 78
    • 83255164111 scopus 로고    scopus 로고
    • Stem cell therapy for neonatal brain injury: perspectives and challenges
    • Titomanlio L., Kavelaars A., Dalous J., et al. Stem cell therapy for neonatal brain injury: perspectives and challenges. Ann Neurol 2011, 70(5):698-712.
    • (2011) Ann Neurol , vol.70 , Issue.5 , pp. 698-712
    • Titomanlio, L.1    Kavelaars, A.2    Dalous, J.3
  • 79
    • 84876278098 scopus 로고    scopus 로고
    • Pluripotent possibilities: human umbilical cord blood cell treatment after neonatal brain injury
    • Verina T., Fatemi A., Johnston M.V., Comi A.M. Pluripotent possibilities: human umbilical cord blood cell treatment after neonatal brain injury. Pediatr Neurol 2013, 48(5):346-354.
    • (2013) Pediatr Neurol , vol.48 , Issue.5 , pp. 346-354
    • Verina, T.1    Fatemi, A.2    Johnston, M.V.3    Comi, A.M.4
  • 80
    • 84896700346 scopus 로고    scopus 로고
    • Stem cells for brain repair in neonatal hypoxia-ischemia
    • Chicha L., Smith T., Guzman R. Stem cells for brain repair in neonatal hypoxia-ischemia. Childs Nerv Syst 2014, 30(1):37-46.
    • (2014) Childs Nerv Syst , vol.30 , Issue.1 , pp. 37-46
    • Chicha, L.1    Smith, T.2    Guzman, R.3
  • 81
    • 84864297868 scopus 로고    scopus 로고
    • Human cord blood for the hypoxic-ischemic neonate
    • Carroll J. Human cord blood for the hypoxic-ischemic neonate. Pediatr Res 2012, 71(4 Pt 2):459-463.
    • (2012) Pediatr Res , vol.71 , Issue.4 , pp. 459-463
    • Carroll, J.1
  • 84
    • 84860211612 scopus 로고    scopus 로고
    • Cell therapy for neonatal hypoxia-ischemia and cerebral palsy
    • Bennet L., Tan S., Van den Heuij L., et al. Cell therapy for neonatal hypoxia-ischemia and cerebral palsy. Ann Neurol 2012, 71(5):589-600.
    • (2012) Ann Neurol , vol.71 , Issue.5 , pp. 589-600
    • Bennet, L.1    Tan, S.2    Van den Heuij, L.3
  • 85
    • 84864136249 scopus 로고    scopus 로고
    • Mesenchymal stem cells as a treatment for neonatal ischemic brain damage
    • van Velthoven C.T., Kavelaars A., Heijnen C.J. Mesenchymal stem cells as a treatment for neonatal ischemic brain damage. Pediatr Res 2012, 71(4 pt 2):474-481.
    • (2012) Pediatr Res , vol.71 , Issue.4 , pp. 474-481
    • van Velthoven, C.T.1    Kavelaars, A.2    Heijnen, C.J.3
  • 86
    • 84913612974 scopus 로고    scopus 로고
    • Regulation of mouse microglia activation and effector functions by bone marrow-derived mesenchymal stem cells
    • Hegyi B., Kornyei Z., Ferenczi S., et al. Regulation of mouse microglia activation and effector functions by bone marrow-derived mesenchymal stem cells. Stem Cells Dev 2014, 23(21):2600-2612.
    • (2014) Stem Cells Dev , vol.23 , Issue.21 , pp. 2600-2612
    • Hegyi, B.1    Kornyei, Z.2    Ferenczi, S.3
  • 87
    • 84865327142 scopus 로고    scopus 로고
    • Human umbilical cord blood-derived mesenchymal stem cell transplantation attenuates severe brain injury by permanent middle cerebral artery occlusion in newborn rats
    • Kim E.S., Ahn S.Y., Im G.H., et al. Human umbilical cord blood-derived mesenchymal stem cell transplantation attenuates severe brain injury by permanent middle cerebral artery occlusion in newborn rats. Pediatr Res 2012, 72(3):277-284.
    • (2012) Pediatr Res , vol.72 , Issue.3 , pp. 277-284
    • Kim, E.S.1    Ahn, S.Y.2    Im, G.H.3
  • 88
    • 77957652253 scopus 로고    scopus 로고
    • Transplantation of magnetically labeled mesenchymal stem cells in a model of perinatal brain injury
    • Chen A., Siow B., Blamire A.M., Lako M., Clowry G.J. Transplantation of magnetically labeled mesenchymal stem cells in a model of perinatal brain injury. Stem Cell Res 2010, 5(3):255-266.
    • (2010) Stem Cell Res , vol.5 , Issue.3 , pp. 255-266
    • Chen, A.1    Siow, B.2    Blamire, A.M.3    Lako, M.4    Clowry, G.J.5
  • 89
    • 73449112945 scopus 로고    scopus 로고
    • Mesenchymal stem-cell transplantation for hypoxic-ischemic brain injury in neonatal rat model
    • Lee J.A., Kim B.I., Jo C.H., et al. Mesenchymal stem-cell transplantation for hypoxic-ischemic brain injury in neonatal rat model. Pediatr Res 2010, 67(1):42-46.
    • (2010) Pediatr Res , vol.67 , Issue.1 , pp. 42-46
    • Lee, J.A.1    Kim, B.I.2    Jo, C.H.3
  • 90
    • 84924908576 scopus 로고    scopus 로고
    • Intraperitoneal and intravenous deliveries are not comparable in terms of drug efficacy and cell distribution in neonatal mice with hypoxia-ischemia
    • Ohshima M., Taguchi A., Tsuda H., et al. Intraperitoneal and intravenous deliveries are not comparable in terms of drug efficacy and cell distribution in neonatal mice with hypoxia-ischemia. Brain Dev 2015, 37(4):376-386.
    • (2015) Brain Dev , vol.37 , Issue.4 , pp. 376-386
    • Ohshima, M.1    Taguchi, A.2    Tsuda, H.3
  • 91
    • 84946082257 scopus 로고    scopus 로고
    • Assessment of long-term safety and efficacy of intranasal mesenchymal stem cell treatment for neonatal brain injury in the mouse
    • Donega V., Nijboer C.H., van Velthoven C.T., et al. Assessment of long-term safety and efficacy of intranasal mesenchymal stem cell treatment for neonatal brain injury in the mouse. Pediatr Res 2015, 78(5):520-526.
    • (2015) Pediatr Res , vol.78 , Issue.5 , pp. 520-526
    • Donega, V.1    Nijboer, C.H.2    van Velthoven, C.T.3
  • 92
    • 77951621676 scopus 로고    scopus 로고
    • Mesenchymal stem cell treatment after neonatal hypoxic-ischemic brain injury improves behavioral outcome and induces neuronal and oligodendrocyte regeneration
    • van Velthoven C.T., Kavelaars A., van Bel F., Heijnen C.J. Mesenchymal stem cell treatment after neonatal hypoxic-ischemic brain injury improves behavioral outcome and induces neuronal and oligodendrocyte regeneration. Brain Behav Immun 2010, 24(3):387-393.
    • (2010) Brain Behav Immun , vol.24 , Issue.3 , pp. 387-393
    • van Velthoven, C.T.1    Kavelaars, A.2    van Bel, F.3    Heijnen, C.J.4
  • 93
    • 77958450795 scopus 로고    scopus 로고
    • Nasal administration of stem cells: a promising novel route to treat neonatal ischemic brain damage
    • van Velthoven C.T., Kavelaars A., van Bel F., Heijnen C.J. Nasal administration of stem cells: a promising novel route to treat neonatal ischemic brain damage. Pediatr Res 2010, 68(5):419-422.
    • (2010) Pediatr Res , vol.68 , Issue.5 , pp. 419-422
    • van Velthoven, C.T.1    Kavelaars, A.2    van Bel, F.3    Heijnen, C.J.4
  • 94
    • 84862752014 scopus 로고    scopus 로고
    • Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice
    • van Velthoven C.T., van de Looij Y., Kavelaars A., et al. Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice. Ann Neurol 2012, 71(6):785-796.
    • (2012) Ann Neurol , vol.71 , Issue.6 , pp. 785-796
    • van Velthoven, C.T.1    van de Looij, Y.2    Kavelaars, A.3
  • 95
    • 84871871927 scopus 로고    scopus 로고
    • Intranasal mesenchymal stem cell treatment for neonatal brain damage: long-term cognitive and sensorimotor improvement
    • Donega V., van Velthoven C.T., Nijboer C.H., et al. Intranasal mesenchymal stem cell treatment for neonatal brain damage: long-term cognitive and sensorimotor improvement. PLoS One 2013, 8(1):e51253.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e51253
    • Donega, V.1    van Velthoven, C.T.2    Nijboer, C.H.3
  • 96
    • 77954736319 scopus 로고    scopus 로고
    • Repeated mesenchymal stem cell treatment after neonatal hypoxia-ischemia has distinct effects on formation and maturation of new neurons and oligodendrocytes leading to restoration of damage, corticospinal motor tract activity, and sensorimotor function
    • van Velthoven C.T., Kavelaars A., van Bel F., Heijnen C.J. Repeated mesenchymal stem cell treatment after neonatal hypoxia-ischemia has distinct effects on formation and maturation of new neurons and oligodendrocytes leading to restoration of damage, corticospinal motor tract activity, and sensorimotor function. J Neurosci 2010, 30(28):9603-9611.
    • (2010) J Neurosci , vol.30 , Issue.28 , pp. 9603-9611
    • van Velthoven, C.T.1    Kavelaars, A.2    van Bel, F.3    Heijnen, C.J.4
  • 97
    • 79961066356 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation changes the gene expression profile of the neonatal ischemic brain
    • van Velthoven C.T., Kavelaars A., van Bel F., Heijnen C.J. Mesenchymal stem cell transplantation changes the gene expression profile of the neonatal ischemic brain. Brain Behav Immun 2011, 25(7):1342-1348.
    • (2011) Brain Behav Immun , vol.25 , Issue.7 , pp. 1342-1348
    • van Velthoven, C.T.1    Kavelaars, A.2    van Bel, F.3    Heijnen, C.J.4
  • 98
    • 84911376433 scopus 로고    scopus 로고
    • Intranasal administration of human msc for ischemic brain injury in the mouse: in vitro and in vivo neuroregenerative functions
    • Donega V., Nijboer C.H., Braccioli L., et al. Intranasal administration of human msc for ischemic brain injury in the mouse: in vitro and in vivo neuroregenerative functions. PLoS One 2014, 9(11):e112339.
    • (2014) PLoS One , vol.9 , Issue.11 , pp. e112339
    • Donega, V.1    Nijboer, C.H.2    Braccioli, L.3
  • 99
    • 84895431932 scopus 로고    scopus 로고
    • Therapeutic potential of genetically modified mesenchymal stem cells after neonatal hypoxic-ischemic brain damage
    • van Velthoven C.T., Braccioli L., Willemen H.L., Kavelaars A., Heijnen C.J. Therapeutic potential of genetically modified mesenchymal stem cells after neonatal hypoxic-ischemic brain damage. Mol Ther 2014, 22(3):645-654.
    • (2014) Mol Ther , vol.22 , Issue.3 , pp. 645-654
    • van Velthoven, C.T.1    Braccioli, L.2    Willemen, H.L.3    Kavelaars, A.4    Heijnen, C.J.5
  • 100
    • 84876875233 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation attenuates brain injury after neonatal stroke
    • van Velthoven C.T., Sheldon R.A., Kavelaars A., et al. Mesenchymal stem cell transplantation attenuates brain injury after neonatal stroke. Stroke 2013, 44(5):1426-1432.
    • (2013) Stroke , vol.44 , Issue.5 , pp. 1426-1432
    • van Velthoven, C.T.1    Sheldon, R.A.2    Kavelaars, A.3
  • 101
    • 84929484644 scopus 로고    scopus 로고
    • Hypothermia augments neuroprotective activity of mesenchymal stem cells for neonatal hypoxic-ischemic encephalopathy
    • Park W.S., Sung S.I., Ahn S.Y., et al. Hypothermia augments neuroprotective activity of mesenchymal stem cells for neonatal hypoxic-ischemic encephalopathy. PLoS One 2015, 10(3):e0120893.
    • (2015) PLoS One , vol.10 , Issue.3 , pp. e0120893
    • Park, W.S.1    Sung, S.I.2    Ahn, S.Y.3
  • 102
    • 72749096723 scopus 로고    scopus 로고
    • Mesenchymal stem cells for the prevention of bronchopulmonary dysplasia: delivering the secretome
    • Abman S.H., Matthay M.A. Mesenchymal stem cells for the prevention of bronchopulmonary dysplasia: delivering the secretome. Am J Respir Crit Care Med 2009, 180(11):1039-1041.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.11 , pp. 1039-1041
    • Abman, S.H.1    Matthay, M.A.2
  • 103
    • 84873713781 scopus 로고    scopus 로고
    • Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/reperfusion injury
    • Chen L., Wang Y., Pan Y., et al. Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/reperfusion injury. Biochem Biophys Res Commun 2013, 431(3):566-571.
    • (2013) Biochem Biophys Res Commun , vol.431 , Issue.3 , pp. 566-571
    • Chen, L.1    Wang, Y.2    Pan, Y.3
  • 104
    • 62549156690 scopus 로고    scopus 로고
    • Ifats collection: the conditioned media of adipose stromal cells protect against hypoxia-ischemia-induced brain damage in neonatal rats
    • Wei X., Du Z., Zhao L., et al. Ifats collection: the conditioned media of adipose stromal cells protect against hypoxia-ischemia-induced brain damage in neonatal rats. Stem Cells 2009, 27(2):478-488.
    • (2009) Stem Cells , vol.27 , Issue.2 , pp. 478-488
    • Wei, X.1    Du, Z.2    Zhao, L.3
  • 105
    • 20844440562 scopus 로고    scopus 로고
    • Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms
    • Togel F., Hu Z., Weiss K., Isaac J., Lange C., Westenfelder C. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005, 289(1):F31-F42.
    • (2005) Am J Physiol Renal Physiol , vol.289 , Issue.1 , pp. F31-F42
    • Togel, F.1    Hu, Z.2    Weiss, K.3    Isaac, J.4    Lange, C.5    Westenfelder, C.6
  • 106
    • 33644805745 scopus 로고    scopus 로고
    • Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells
    • Nakagami H., Maeda K., Morishita R., et al. Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells. Arterioscler Thromb Vasc Biol 2005, 25(12):2542-2547.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.12 , pp. 2542-2547
    • Nakagami, H.1    Maeda, K.2    Morishita, R.3
  • 107
    • 33646526915 scopus 로고    scopus 로고
    • Role of stromal-derived factor-1 in the hematopoietic-supporting activity of human mesenchymal stem cells
    • Van Overstraeten-Schlogel N., Beguin Y., Gothot A. Role of stromal-derived factor-1 in the hematopoietic-supporting activity of human mesenchymal stem cells. Eur J Haematol 2006, 76(6):488-493.
    • (2006) Eur J Haematol , vol.76 , Issue.6 , pp. 488-493
    • Van Overstraeten-Schlogel, N.1    Beguin, Y.2    Gothot, A.3
  • 108
    • 34547402979 scopus 로고    scopus 로고
    • Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury
    • Ortiz L.A., Dutreil M., Fattman C., et al. Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury. Proc Natl Acad Sci U S A 2007, 104(26):11002-11007.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.26 , pp. 11002-11007
    • Ortiz, L.A.1    Dutreil, M.2    Fattman, C.3
  • 109
    • 84887821866 scopus 로고    scopus 로고
    • Proteomic techniques for characterisation of mesenchymal stem cell secretome
    • Kupcova Skalnikova H. Proteomic techniques for characterisation of mesenchymal stem cell secretome. Biochimie 2013, 95(12):2196-2211.
    • (2013) Biochimie , vol.95 , Issue.12 , pp. 2196-2211
    • Kupcova Skalnikova, H.1
  • 110
    • 84887823573 scopus 로고    scopus 로고
    • Uncovering the secretes of mesenchymal stem cells
    • Lavoie J.R., Rosu-Myles M. Uncovering the secretes of mesenchymal stem cells. Biochimie 2013, 95(12):2212-2221.
    • (2013) Biochimie , vol.95 , Issue.12 , pp. 2212-2221
    • Lavoie, J.R.1    Rosu-Myles, M.2
  • 111
    • 68849129712 scopus 로고    scopus 로고
    • Membrane vesicles as conveyors of immune responses
    • Thery C., Ostrowski M., Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol 2009, 9(8):581-593.
    • (2009) Nat Rev Immunol , vol.9 , Issue.8 , pp. 581-593
    • Thery, C.1    Ostrowski, M.2    Segura, E.3
  • 112
    • 43249109372 scopus 로고    scopus 로고
    • Isolation and characterization of exosomes from cell culture supernatants and biological fluids
    • Thery C., Amigorena S., Raposo G., Clayton A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol 2006, [chapter 3: unit] 3:22.
    • (2006) Curr Protoc Cell Biol , pp. 22
    • Thery, C.1    Amigorena, S.2    Raposo, G.3    Clayton, A.4
  • 113
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: composition, biogenesis and function
    • Thery C., Zitvogel L., Amigorena S. Exosomes: composition, biogenesis and function. Nat Rev Immunol 2002, 2(8):569-579.
    • (2002) Nat Rev Immunol , vol.2 , Issue.8 , pp. 569-579
    • Thery, C.1    Zitvogel, L.2    Amigorena, S.3
  • 114
    • 24644485206 scopus 로고    scopus 로고
    • Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses
    • Segura E., Amigorena S., Thery C. Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses. Blood Cells Mol Dis 2005, 35(2):89-93.
    • (2005) Blood Cells Mol Dis , vol.35 , Issue.2 , pp. 89-93
    • Segura, E.1    Amigorena, S.2    Thery, C.3
  • 115
    • 77449102731 scopus 로고    scopus 로고
    • Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages
    • Barres C., Blanc L., Bette-Bobillo P., et al. Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages. Blood 2010, 115(3):696-705.
    • (2010) Blood , vol.115 , Issue.3 , pp. 696-705
    • Barres, C.1    Blanc, L.2    Bette-Bobillo, P.3
  • 116
    • 77957269172 scopus 로고    scopus 로고
    • Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy
    • Tian T., Wang Y., Wang H., Zhu Z., Xiao Z. Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy. J Cell Biochem 2010, 111(2):488-496.
    • (2010) J Cell Biochem , vol.111 , Issue.2 , pp. 488-496
    • Tian, T.1    Wang, Y.2    Wang, H.3    Zhu, Z.4    Xiao, Z.5
  • 117
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport rna and proteins that promote tumour growth and provide diagnostic biomarkers
    • Skog J., Wurdinger T., van Rijn S., et al. Glioblastoma microvesicles transport rna and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 2008, 10(12):1470-1476.
    • (2008) Nat Cell Biol , vol.10 , Issue.12 , pp. 1470-1476
    • Skog, J.1    Wurdinger, T.2    van Rijn, S.3
  • 118
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mrnas and micrornas is a novel mechanism of genetic exchange between cells
    • Valadi H., Ekstrom K., Bossios A., Sjostrand M., Lee J.J., Lotvall J.O. Exosome-mediated transfer of mrnas and micrornas is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007, 9(6):654-659.
    • (2007) Nat Cell Biol , vol.9 , Issue.6 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 119
    • 0019874126 scopus 로고
    • Exfoliation of membrane ecto-enzymes in the form of micro-vesicles
    • Trams E.G., Lauter C.J., Salem N., Heine U. Exfoliation of membrane ecto-enzymes in the form of micro-vesicles. Biochim Biophys Acta 1981, 645(1):63-70.
    • (1981) Biochim Biophys Acta , vol.645 , Issue.1 , pp. 63-70
    • Trams, E.G.1    Lauter, C.J.2    Salem, N.3    Heine, U.4
  • 120
    • 0020956787 scopus 로고
    • Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor
    • Pan B.T., Johnstone R.M. Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Cell 1983, 33(3):967-978.
    • (1983) Cell , vol.33 , Issue.3 , pp. 967-978
    • Pan, B.T.1    Johnstone, R.M.2
  • 121
    • 0023645106 scopus 로고
    • Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)
    • Johnstone R.M., Adam M., Hammond J.R., Orr L., Turbide C. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem 1987, 262(19):9412-9420.
    • (1987) J Biol Chem , vol.262 , Issue.19 , pp. 9412-9420
    • Johnstone, R.M.1    Adam, M.2    Hammond, J.R.3    Orr, L.4    Turbide, C.5
  • 125
    • 84859726068 scopus 로고    scopus 로고
    • Bone marrow-derived conventional, but not cloned, mesenchymal stem cells suppress lymphocyte proliferation and prevent graft-versus-host disease in rats
    • Kitazawa Y., Li X.K., Xie L., Zhu P., Kimura H., Takahara S. Bone marrow-derived conventional, but not cloned, mesenchymal stem cells suppress lymphocyte proliferation and prevent graft-versus-host disease in rats. Cell Transplant 2012, 21(2-3):581-590.
    • (2012) Cell Transplant , vol.21 , Issue.2-3 , pp. 581-590
    • Kitazawa, Y.1    Li, X.K.2    Xie, L.3    Zhu, P.4    Kimura, H.5    Takahara, S.6
  • 126
    • 84874443222 scopus 로고    scopus 로고
    • The immunosuppressive effect of mesenchymal stromal cells on b lymphocytes is mediated by membrane vesicles
    • Budoni M., Fierabracci A., Luciano R., Petrini S., Di Ciommo V., Muraca M. The immunosuppressive effect of mesenchymal stromal cells on b lymphocytes is mediated by membrane vesicles. Cell Transplant 2013, 22(2):369-379.
    • (2013) Cell Transplant , vol.22 , Issue.2 , pp. 369-379
    • Budoni, M.1    Fierabracci, A.2    Luciano, R.3    Petrini, S.4    Di Ciommo, V.5    Muraca, M.6
  • 127
    • 0345015348 scopus 로고    scopus 로고
    • Presentation of donor major histocompatibility complex antigens by bone marrow dendritic cell-derived exosomes modulates allograft rejection
    • Peche H., Heslan M., Usal C., Amigorena S., Cuturi M.C. Presentation of donor major histocompatibility complex antigens by bone marrow dendritic cell-derived exosomes modulates allograft rejection. Transplantation 2003, 76(10):1503-1510.
    • (2003) Transplantation , vol.76 , Issue.10 , pp. 1503-1510
    • Peche, H.1    Heslan, M.2    Usal, C.3    Amigorena, S.4    Cuturi, M.C.5
  • 128
    • 84870239895 scopus 로고    scopus 로고
    • Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension
    • Lee C., Mitsialis S.A., Aslam M., et al. Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension. Circulation 2012, 126(22):2601-2611.
    • (2012) Circulation , vol.126 , Issue.22 , pp. 2601-2611
    • Lee, C.1    Mitsialis, S.A.2    Aslam, M.3
  • 129
    • 41549162430 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure
    • Parekkadan B., van Poll D., Suganuma K., et al. Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure. PLoS One 2007, 2(9):e941.
    • (2007) PLoS One , vol.2 , Issue.9 , pp. e941
    • Parekkadan, B.1    van Poll, D.2    Suganuma, K.3
  • 130
    • 84857838864 scopus 로고    scopus 로고
    • Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease
    • Ranganath S.H., Levy O., Inamdar M.S., Karp J.M. Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease. Cell Stem Cell 2012, 10(3):244-258.
    • (2012) Cell Stem Cell , vol.10 , Issue.3 , pp. 244-258
    • Ranganath, S.H.1    Levy, O.2    Inamdar, M.S.3    Karp, J.M.4
  • 131
    • 84867119899 scopus 로고    scopus 로고
    • Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy
    • Baglio S.R., Pegtel D.M., Baldini N. Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy. Front Physiol 2012, 3:359.
    • (2012) Front Physiol , vol.3 , pp. 359
    • Baglio, S.R.1    Pegtel, D.M.2    Baldini, N.3
  • 132
    • 84874988827 scopus 로고    scopus 로고
    • Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery
    • Yeo R.W., Lai R.C., Zhang B., et al. Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery. Adv Drug Deliv Rev 2013, 65(3):336-341.
    • (2013) Adv Drug Deliv Rev , vol.65 , Issue.3 , pp. 336-341
    • Yeo, R.W.1    Lai, R.C.2    Zhang, B.3
  • 133
    • 77952293014 scopus 로고    scopus 로고
    • Exosome secreted by msc reduces myocardial ischemia/reperfusion injury
    • Lai R.C., Arslan F., Lee M.M., et al. Exosome secreted by msc reduces myocardial ischemia/reperfusion injury. Stem Cell Res 2010, 4(3):214-222.
    • (2010) Stem Cell Res , vol.4 , Issue.3 , pp. 214-222
    • Lai, R.C.1    Arslan, F.2    Lee, M.M.3
  • 134
    • 84876875077 scopus 로고    scopus 로고
    • Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro
    • Zhou Y., Xu H., Xu W., et al. Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro. Stem Cell Res Ther 2013, 4(2):34.
    • (2013) Stem Cell Res Ther , vol.4 , Issue.2 , pp. 34
    • Zhou, Y.1    Xu, H.2    Xu, W.3
  • 135
    • 65649089130 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived microvesicles protect against acute tubular injury
    • Bruno S., Grange C., Deregibus M.C., et al. Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol 2009, 20(5):1053-1067.
    • (2009) J Am Soc Nephrol , vol.20 , Issue.5 , pp. 1053-1067
    • Bruno, S.1    Grange, C.2    Deregibus, M.C.3
  • 136
    • 0026047960 scopus 로고
    • Protection against infarction afforded by preconditioning is mediated by a1 adenosine receptors in rabbit heart
    • Liu G.S., Thornton J., Van Winkle D.M., Stanley A.W., Olsson R.A., Downey J.M. Protection against infarction afforded by preconditioning is mediated by a1 adenosine receptors in rabbit heart. Circulation 1991, 84(1):350-356.
    • (1991) Circulation , vol.84 , Issue.1 , pp. 350-356
    • Liu, G.S.1    Thornton, J.2    Van Winkle, D.M.3    Stanley, A.W.4    Olsson, R.A.5    Downey, J.M.6
  • 137
    • 0027471927 scopus 로고
    • Ischemic preconditioning increases adenosine release and 5'-nucleotidase activity during myocardial ischemia and reperfusion in dogs. Implications for myocardial salvage
    • Kitakaze M., Hori M., Takashima S., Sato H., Inoue M., Kamada T. Ischemic preconditioning increases adenosine release and 5'-nucleotidase activity during myocardial ischemia and reperfusion in dogs. Implications for myocardial salvage. Circulation 1993, 87(1):208-215.
    • (1993) Circulation , vol.87 , Issue.1 , pp. 208-215
    • Kitakaze, M.1    Hori, M.2    Takashima, S.3    Sato, H.4    Inoue, M.5    Kamada, T.6
  • 138
    • 84873919177 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived exosomes increase atp levels, decrease oxidative stress and activate pi3k/akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
    • Arslan F., Lai R.C., Smeets M.B., et al. Mesenchymal stem cell-derived exosomes increase atp levels, decrease oxidative stress and activate pi3k/akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury. Stem Cell Res 2013, 10(3):301-312.
    • (2013) Stem Cell Res , vol.10 , Issue.3 , pp. 301-312
    • Arslan, F.1    Lai, R.C.2    Smeets, M.B.3
  • 139
    • 84861463136 scopus 로고    scopus 로고
    • Endothelial progenitor cell-derived microvesicles improve neovascularization in a murine model of hindlimb ischemia
    • Ranghino A., Cantaluppi V., Grange C., et al. Endothelial progenitor cell-derived microvesicles improve neovascularization in a murine model of hindlimb ischemia. Int J Immunopathol Pharmacol 2012, 25(1):75-85.
    • (2012) Int J Immunopathol Pharmacol , vol.25 , Issue.1 , pp. 75-85
    • Ranghino, A.1    Cantaluppi, V.2    Grange, C.3
  • 140
    • 34948834742 scopus 로고    scopus 로고
    • Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mrna
    • Deregibus M.C., Cantaluppi V., Calogero R., et al. Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mrna. Blood 2007, 110(7):2440-2448.
    • (2007) Blood , vol.110 , Issue.7 , pp. 2440-2448
    • Deregibus, M.C.1    Cantaluppi, V.2    Calogero, R.3
  • 141
    • 79955571241 scopus 로고    scopus 로고
    • Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury
    • Gatti S., Bruno S., Deregibus M.C., et al. Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. Nephrol Dial Transplant 2011, 26(5):1474-1483.
    • (2011) Nephrol Dial Transplant , vol.26 , Issue.5 , pp. 1474-1483
    • Gatti, S.1    Bruno, S.2    Deregibus, M.C.3
  • 142
    • 84864530691 scopus 로고    scopus 로고
    • Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia-reperfusion injury by microrna-dependent reprogramming of resident renal cells
    • Cantaluppi V., Gatti S., Medica D., et al. Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia-reperfusion injury by microrna-dependent reprogramming of resident renal cells. Kidney Int 2012, 82(4):412-427.
    • (2012) Kidney Int , vol.82 , Issue.4 , pp. 412-427
    • Cantaluppi, V.1    Gatti, S.2    Medica, D.3
  • 143
    • 84938578435 scopus 로고    scopus 로고
    • Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction
    • Khan M., Nickoloff E., Abramova T., et al. Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction. Circ Res 2015, 117(1):52-64.
    • (2015) Circ Res , vol.117 , Issue.1 , pp. 52-64
    • Khan, M.1    Nickoloff, E.2    Abramova, T.3
  • 144
    • 84964329540 scopus 로고    scopus 로고
    • Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury
    • Zhang Y., Chopp M., Meng Y., et al. Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury. J Neurosurg 2015, 122(4):856-867.
    • (2015) J Neurosurg , vol.122 , Issue.4 , pp. 856-867
    • Zhang, Y.1    Chopp, M.2    Meng, Y.3
  • 145
    • 84942162960 scopus 로고    scopus 로고
    • Extracellular vesicles improve post-stroke neuroregeneration and prevent postischemic immunosuppression
    • Doeppner T.R., Herz J., Gorgens A., et al. Extracellular vesicles improve post-stroke neuroregeneration and prevent postischemic immunosuppression. Stem Cells Transl Med 2015, 4(10):1131-1143.
    • (2015) Stem Cells Transl Med , vol.4 , Issue.10 , pp. 1131-1143
    • Doeppner, T.R.1    Herz, J.2    Gorgens, A.3
  • 146
    • 84936998148 scopus 로고    scopus 로고
    • Stem cell therapies in clinical trials: progress and challenges
    • Trounson A., McDonald C. Stem cell therapies in clinical trials: progress and challenges. Cell Stem Cell 2015, 17(1):11-22.
    • (2015) Cell Stem Cell , vol.17 , Issue.1 , pp. 11-22
    • Trounson, A.1    McDonald, C.2
  • 147
    • 84949514545 scopus 로고    scopus 로고
    • Stem cell therapy for bronchopulmonary dysplasia: bench to bedside translation
    • Ahn S.Y., Chang Y.S., Park W.S. Stem cell therapy for bronchopulmonary dysplasia: bench to bedside translation. J Korean Med Sci 2015, 30(5):509-513.
    • (2015) J Korean Med Sci , vol.30 , Issue.5 , pp. 509-513
    • Ahn, S.Y.1    Chang, Y.S.2    Park, W.S.3
  • 148
    • 84899097253 scopus 로고    scopus 로고
    • Mesenchymal stem cells for bronchopulmonary dysplasia: phase 1 dose-escalation clinical trial
    • Chang Y.S., Ahn S.Y., Yoo H.S., et al. Mesenchymal stem cells for bronchopulmonary dysplasia: phase 1 dose-escalation clinical trial. J Pediatr 2014, 164(5):966-972.e6.
    • (2014) J Pediatr , vol.164 , Issue.5 , pp. 966-972.e6
    • Chang, Y.S.1    Ahn, S.Y.2    Yoo, H.S.3
  • 149
    • 84899065815 scopus 로고    scopus 로고
    • Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy
    • Cotten C.M., Murtha A.P., Goldberg R.N., et al. Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy. J Pediatr 2014, 164(5):973-979.e1.
    • (2014) J Pediatr , vol.164 , Issue.5 , pp. 973-979.e1
    • Cotten, C.M.1    Murtha, A.P.2    Goldberg, R.N.3
  • 150
    • 84868091993 scopus 로고    scopus 로고
    • Safety of cell therapy with mesenchymal stromal cells (safecell): a systematic review and meta-analysis of clinical trials
    • Lalu M.M., McIntyre L., Pugliese C., et al. Safety of cell therapy with mesenchymal stromal cells (safecell): a systematic review and meta-analysis of clinical trials. PLoS One 2012, 7(10):e47559.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e47559
    • Lalu, M.M.1    McIntyre, L.2    Pugliese, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.