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Volumn 71, Issue 5, 2012, Pages 589-600

Cell therapy for neonatal hypoxia-ischemia and cerebral palsy

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; MAGNESIUM SULFATE; NEUROTROPHIC FACTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; XENON;

EID: 84860211612     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.22670     Document Type: Article
Times cited : (139)

References (78)
  • 1
    • 77954315863 scopus 로고    scopus 로고
    • Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy
    • Kurinczuk JJ, White-Koning M, Badawi N,. Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy. Early Hum Dev 2010; 86: 329-338.
    • (2010) Early Hum Dev , vol.86 , pp. 329-338
    • Kurinczuk, J.J.1    White-Koning, M.2    Badawi, N.3
  • 2
    • 24044548649 scopus 로고    scopus 로고
    • Neuropsychological and educational problems at school age associated with neonatal encephalopathy
    • Marlow N, Rose AS, Rands CE, Draper ES,. Neuropsychological and educational problems at school age associated with neonatal encephalopathy. Arch Dis Child Fetal Neonatal Ed 2005; 90: F380-F387.
    • (2005) Arch Dis Child Fetal Neonatal Ed , vol.90
    • Marlow, N.1    Rose, A.S.2    Rands, C.E.3    Draper, E.S.4
  • 3
    • 77149149663 scopus 로고    scopus 로고
    • Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: Synthesis and meta-analysis of trial data
    • Edwards AD, Brocklehurst P, Gunn AJ, et al. Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data. Br Med J 2010; 340: c363.
    • (2010) Br Med J , vol.340
    • Edwards, A.D.1    Brocklehurst, P.2    Gunn, A.J.3
  • 4
    • 69249249242 scopus 로고    scopus 로고
    • Fetal hypoxia insults and patterns of brain injury: Insights from animal models
    • Gunn AJ, Bennet L,. Fetal hypoxia insults and patterns of brain injury: insights from animal models. Clin Perinatol 2009; 36: 579-593.
    • (2009) Clin Perinatol , vol.36 , pp. 579-593
    • Gunn, A.J.1    Bennet, L.2
  • 5
    • 33645326851 scopus 로고    scopus 로고
    • Relationship between evolving epileptiform activity and delayed loss of mitochondrial activity after asphyxia measured by near-infrared spectroscopy in preterm fetal sheep
    • Bennet L, Roelfsema V, Pathipati P, et al. Relationship between evolving epileptiform activity and delayed loss of mitochondrial activity after asphyxia measured by near-infrared spectroscopy in preterm fetal sheep. J Physiol 2006; 572: 141-154.
    • (2006) J Physiol , vol.572 , pp. 141-154
    • Bennet, L.1    Roelfsema, V.2    Pathipati, P.3
  • 6
    • 0031034474 scopus 로고    scopus 로고
    • Dramatic neuronal rescue with prolonged selective head cooling after ischemia in fetal lambs
    • Gunn AJ, Gunn TR, de Haan HH, et al. Dramatic neuronal rescue with prolonged selective head cooling after ischemia in fetal lambs. J Clin Invest 1997; 99: 248-256.
    • (1997) J Clin Invest , vol.99 , pp. 248-256
    • Gunn, A.J.1    Gunn, T.R.2    De Haan, H.H.3
  • 7
    • 33645297101 scopus 로고    scopus 로고
    • Post-hypoxic hypoperfusion is associated with suppression of cerebral metabolism and increased tissue oxygenation in near-term fetal sheep
    • Jensen EC, Bennet L, Hunter CJ, et al. Post-hypoxic hypoperfusion is associated with suppression of cerebral metabolism and increased tissue oxygenation in near-term fetal sheep. J Physiol 2006; 572: 131-139.
    • (2006) J Physiol , vol.572 , pp. 131-139
    • Jensen, E.C.1    Bennet, L.2    Hunter, C.J.3
  • 8
    • 0028079731 scopus 로고
    • Delayed ("secondary") cerebral energy failure after acute hypoxia-ischemia in the newborn piglet: Continuous 48-hour studies by phosphorus magnetic resonance spectroscopy
    • Lorek A, Takei Y, Cady EB, et al. Delayed ("secondary") cerebral energy failure after acute hypoxia-ischemia in the newborn piglet: continuous 48-hour studies by phosphorus magnetic resonance spectroscopy. Pediatr Res 1994; 36: 699-706.
    • (1994) Pediatr Res , vol.36 , pp. 699-706
    • Lorek, A.1    Takei, Y.2    Cady, E.B.3
  • 9
    • 0030661992 scopus 로고    scopus 로고
    • Relation of deranged neonatal cerebral oxidative metabolism with neurodevelopmental outcome and head circumference at 4 years
    • Roth SC, Baudin J, Cady E, et al. Relation of deranged neonatal cerebral oxidative metabolism with neurodevelopmental outcome and head circumference at 4 years. Dev Med Child Neurol 1997; 39: 718-725.
    • (1997) Dev Med Child Neurol , vol.39 , pp. 718-725
    • Roth, S.C.1    Baudin, J.2    Cady, E.3
  • 10
    • 0028825745 scopus 로고
    • Delayed postischemic hypothermia: A six month survival study using behavioral and histological assessments of neuroprotection
    • Colbourne F, Corbett D,. Delayed postischemic hypothermia: a six month survival study using behavioral and histological assessments of neuroprotection. J Neurosci 1995; 15: 7250-7260.
    • (1995) J Neurosci , vol.15 , pp. 7250-7260
    • Colbourne, F.1    Corbett, D.2
  • 11
    • 0035743242 scopus 로고    scopus 로고
    • Delayed cerebral atrophy following moderate hypoxia-ischemia in the immature rat
    • Geddes R, Vannucci RC, Vannucci SJ,. Delayed cerebral atrophy following moderate hypoxia-ischemia in the immature rat. Dev Neurosci 2001; 23: 180-185.
    • (2001) Dev Neurosci , vol.23 , pp. 180-185
    • Geddes, R.1    Vannucci, R.C.2    Vannucci, S.J.3
  • 12
    • 57749089871 scopus 로고    scopus 로고
    • Delayed neural network degeneration after neonatal hypoxia-ischemia
    • Stone BS, Zhang J, Mack DW, et al. Delayed neural network degeneration after neonatal hypoxia-ischemia. Ann Neurol 2008; 64: 535-546.
    • (2008) Ann Neurol , vol.64 , pp. 535-546
    • Stone, B.S.1    Zhang, J.2    MacK, D.W.3
  • 13
  • 14
    • 33646146181 scopus 로고    scopus 로고
    • Hypothermic neuroprotection
    • Gunn AJ, Thoresen M,. Hypothermic neuroprotection. NeuroRx 2006; 3: 154-169.
    • (2006) NeuroRx , vol.3 , pp. 154-169
    • Gunn, A.J.1    Thoresen, M.2
  • 16
    • 84860133328 scopus 로고    scopus 로고
    • University of California, San Francisco Study NCT00719407, Available at: (accessed on 28 September 2011)
    • University of California, San Francisco. Neonatal erythropoietin in asphyxiated term newborns (NEAT). Study NCT00719407, 2011. Available at: (accessed on 28 September 2011).
    • (2011) Neonatal Erythropoietin in Asphyxiated Term Newborns (NEAT)
  • 17
    • 56049105381 scopus 로고    scopus 로고
    • Brain cooling for preterm infants
    • Gunn AJ, Bennet L,. Brain cooling for preterm infants. Clin Perinatol 2008; 35: 735-748.
    • (2008) Clin Perinatol , vol.35 , pp. 735-748
    • Gunn, A.J.1    Bennet, L.2
  • 18
    • 77649113591 scopus 로고    scopus 로고
    • Committee Opinion No. 455: Magnesium sulfate before anticipated preterm birth for neuroprotection
    • Committee Opinion No. 455: Magnesium sulfate before anticipated preterm birth for neuroprotection. Obstet Gynecol 2010; 115: 669-671.
    • (2010) Obstet Gynecol , vol.115 , pp. 669-671
  • 19
    • 78650268210 scopus 로고    scopus 로고
    • Antenatal magnesium sulphate may prevent cerebral palsy in preterm infants-but are we convinced? Evaluation of an apparently conclusive meta-analysis with trial sequential analysis
    • Huusom LD, Secher NJ, Pryds O, et al. Antenatal magnesium sulphate may prevent cerebral palsy in preterm infants-but are we convinced? Evaluation of an apparently conclusive meta-analysis with trial sequential analysis. BJOG 2011; 118: 1-5.
    • (2011) BJOG , vol.118 , pp. 1-5
    • Huusom, L.D.1    Secher, N.J.2    Pryds, O.3
  • 20
    • 84860185789 scopus 로고    scopus 로고
    • Available at: (accessed on 16 April 2011)
    • Cord Blood Registry. 2011. Available at: (accessed on 16 April 2011).
    • (2011) Cord Blood Registry
  • 21
    • 0033937239 scopus 로고    scopus 로고
    • Severe respiratory depression after dimethylsulphoxide-containing autologous stem cell infusion in a patient with AL amyloidosis
    • Benekli M, Anderson B, Wentling D, et al. Severe respiratory depression after dimethylsulphoxide-containing autologous stem cell infusion in a patient with AL amyloidosis. Bone Marrow Transplant 2000; 25: 1299-1301.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 1299-1301
    • Benekli, M.1    Anderson, B.2    Wentling, D.3
  • 22
    • 77956333060 scopus 로고    scopus 로고
    • Differences in quality between privately and publicly banked umbilical cord blood units: A pilot study of autologous cord blood infusion in children with acquired neurologic disorders
    • Sun J, Allison J, McLaughlin C, et al. Differences in quality between privately and publicly banked umbilical cord blood units: a pilot study of autologous cord blood infusion in children with acquired neurologic disorders. Transfusion 2010; 50: 1980-1987.
    • (2010) Transfusion , vol.50 , pp. 1980-1987
    • Sun, J.1    Allison, J.2    McLaughlin, C.3
  • 23
    • 50349100425 scopus 로고    scopus 로고
    • The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response
    • Dressel R, Schindehutte J, Kuhlmann T, et al. The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response. PloS One 2008; 3: e2622.
    • (2008) PloS One , vol.3
    • Dressel, R.1    Schindehutte, J.2    Kuhlmann, T.3
  • 24
    • 79957807595 scopus 로고    scopus 로고
    • Immunogenicity of induced pluripotent stem cells
    • Zhao T, Zhang ZN, Rong Z, Xu Y,. Immunogenicity of induced pluripotent stem cells. Nature 2011; 474: 212-215.
    • (2011) Nature , vol.474 , pp. 212-215
    • Zhao, T.1    Zhang, Z.N.2    Rong, Z.3    Xu, Y.4
  • 25
    • 77954449924 scopus 로고    scopus 로고
    • Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells
    • Dressel R, Nolte J, Elsner L, et al. Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells. FASEB J 2010; 24: 2164-2177.
    • (2010) FASEB J , vol.24 , pp. 2164-2177
    • Dressel, R.1    Nolte, J.2    Elsner, L.3
  • 26
    • 0034610365 scopus 로고    scopus 로고
    • Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain
    • Laywell ED, Rakic P, Kukekov VG, et al. Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain. Proc Natl Acad Sci U S A 2000; 97: 13883-13888.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13883-13888
    • Laywell, E.D.1    Rakic, P.2    Kukekov, V.G.3
  • 27
    • 0038363452 scopus 로고    scopus 로고
    • Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos
    • Keene CD, Ortiz-Gonzalez XR, Jiang Y, et al. Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos. Cell Transplant 2003; 12: 201-213.
    • (2003) Cell Transplant , vol.12 , pp. 201-213
    • Keene, C.D.1    Ortiz-Gonzalez, X.R.2    Jiang, Y.3
  • 28
    • 0019366919 scopus 로고
    • The influence of immaturity on hypoxic-ischemic brain damage in the rat
    • Rice JE III, Vannucci RC, Brierley JB,. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 1981; 9: 131-141.
    • (1981) Ann Neurol , vol.9 , pp. 131-141
    • Rice Iii, J.E.1    Vannucci, R.C.2    Brierley, J.B.3
  • 29
    • 0018372689 scopus 로고
    • Comparative aspects of the brain growth spurt
    • Dobbing J, Sands J,. Comparative aspects of the brain growth spurt. Early Hum Dev 1979; 3: 79-83.
    • (1979) Early Hum Dev , vol.3 , pp. 79-83
    • Dobbing, J.1    Sands, J.2
  • 30
    • 0025734533 scopus 로고
    • At what age is the developing cerebral cortex of the rat comparable to that of the full-term newborn human baby?
    • Romijn HJ, Hofman MA, Gramsbergen A,. At what age is the developing cerebral cortex of the rat comparable to that of the full-term newborn human baby? Early Hum Dev 1991; 26: 61-67.
    • (1991) Early Hum Dev , vol.26 , pp. 61-67
    • Romijn, H.J.1    Hofman, M.A.2    Gramsbergen, A.3
  • 31
    • 0343703485 scopus 로고    scopus 로고
    • Use of fetal cortical grafts in hypoxic-ischemic brain injury in neonatal rats
    • Elsayed MH, Hogan TP, Shaw PL, Castro AJ,. Use of fetal cortical grafts in hypoxic-ischemic brain injury in neonatal rats. Exp Neurol 1996; 137: 127-141.
    • (1996) Exp Neurol , vol.137 , pp. 127-141
    • Elsayed, M.H.1    Hogan, T.P.2    Shaw, P.L.3    Castro, A.J.4
  • 32
    • 0031258146 scopus 로고    scopus 로고
    • Transplantation of fetal neocortex ameliorates sensorimotor and locomotor deficits following neonatal ischemic-hypoxic brain injury in rats
    • Jansen EM, Solberg L, Underhill S, et al. Transplantation of fetal neocortex ameliorates sensorimotor and locomotor deficits following neonatal ischemic-hypoxic brain injury in rats. Exp Neurol 1997; 147: 487-497.
    • (1997) Exp Neurol , vol.147 , pp. 487-497
    • Jansen, E.M.1    Solberg, L.2    Underhill, S.3
  • 33
    • 33745217891 scopus 로고    scopus 로고
    • Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: Evidence from the effect of hypoxia-ischemia in the CNS on clonal "reporter" neural stem cells
    • Park KI, Hack MA, Ourednik J, et al. Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: evidence from the effect of hypoxia-ischemia in the CNS on clonal "reporter" neural stem cells. Exp Neurol 2006; 199: 156-178.
    • (2006) Exp Neurol , vol.199 , pp. 156-178
    • Park, K.I.1    Hack, M.A.2    Ourednik, J.3
  • 34
    • 19944426191 scopus 로고    scopus 로고
    • Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway
    • Imitola J, Raddassi K, Park KI, et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci U S A 2004; 101: 18117-18122.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 18117-18122
    • Imitola, J.1    Raddassi, K.2    Park, K.I.3
  • 35
    • 33748430332 scopus 로고    scopus 로고
    • Transplantation of multipotent astrocytic stem cells into a rat model of neonatal hypoxic-ischemic encephalopathy
    • Zheng T, Rossignol C, Leibovici A, et al. Transplantation of multipotent astrocytic stem cells into a rat model of neonatal hypoxic-ischemic encephalopathy. Brain Res 2006; 1112: 99-105.
    • (2006) Brain Res , vol.1112 , pp. 99-105
    • Zheng, T.1    Rossignol, C.2    Leibovici, A.3
  • 36
    • 45749107508 scopus 로고    scopus 로고
    • Reduction of brain injury in neonatal hypoxic-ischemic rats by intracerebroventricular injection of neural stem/progenitor cells together with chondroitinase ABC
    • Sato Y, Nakanishi K, Hayakawa M, et al. Reduction of brain injury in neonatal hypoxic-ischemic rats by intracerebroventricular injection of neural stem/progenitor cells together with chondroitinase ABC. Reprod Sci 2008; 15: 613-620.
    • (2008) Reprod Sci , vol.15 , pp. 613-620
    • Sato, Y.1    Nakanishi, K.2    Hayakawa, M.3
  • 37
    • 77649120565 scopus 로고    scopus 로고
    • Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury
    • Daadi MM, Davis AS, Arac A, et al. Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury. Stroke 2010; 41: 516-523.
    • (2010) Stroke , vol.41 , pp. 516-523
    • Daadi, M.M.1    Davis, A.S.2    Arac, A.3
  • 38
    • 34347345058 scopus 로고    scopus 로고
    • Treatment of hypoxic-ischemic encephalopathy in mouse by transplantation of embryonic stem cell-derived cells
    • Ma J, Wang Y, Yang J, et al. Treatment of hypoxic-ischemic encephalopathy in mouse by transplantation of embryonic stem cell-derived cells. Neurochem Int 2007; 51: 57-65.
    • (2007) Neurochem Int , vol.51 , pp. 57-65
    • Ma, J.1    Wang, Y.2    Yang, J.3
  • 39
    • 0036842501 scopus 로고    scopus 로고
    • The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue
    • Park KI, Teng YD, Snyder EY,. The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue. Nat Biotechnol 2002; 20: 1111-1117.
    • (2002) Nat Biotechnol , vol.20 , pp. 1111-1117
    • Park, K.I.1    Teng, Y.D.2    Snyder, E.Y.3
  • 40
    • 33646572210 scopus 로고    scopus 로고
    • Behavioral and histological characterization of intrahippocampal grafts of human bone marrow-derived multipotent progenitor cells in neonatal rats with hypoxic-ischemic injury
    • Yasuhara T, Matsukawa N, Yu G, et al. Behavioral and histological characterization of intrahippocampal grafts of human bone marrow-derived multipotent progenitor cells in neonatal rats with hypoxic-ischemic injury. Cell Transplant 2006; 15: 231-238.
    • (2006) Cell Transplant , vol.15 , pp. 231-238
    • Yasuhara, T.1    Matsukawa, N.2    Yu, G.3
  • 41
    • 54949145003 scopus 로고    scopus 로고
    • Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats
    • Yasuhara T, Hara K, Maki M, et al. Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats. J Cereb Blood Flow Metab 2008; 28: 1804-1810.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1804-1810
    • Yasuhara, T.1    Hara, K.2    Maki, M.3
  • 42
    • 77951621676 scopus 로고    scopus 로고
    • Mesenchymal stem cell treatment after neonatal hypoxic-ischemic brain injury improves behavioral outcome and induces neuronal and oligodendrocyte regeneration
    • van Velthoven CT, Kavelaars A, van Bel F, Heijnen CJ,. Mesenchymal stem cell treatment after neonatal hypoxic-ischemic brain injury improves behavioral outcome and induces neuronal and oligodendrocyte regeneration. Brain Behav Immun 2010; 24: 387-393.
    • (2010) Brain Behav Immun , vol.24 , pp. 387-393
    • Van Velthoven, C.T.1    Kavelaars, A.2    Van Bel, F.3    Heijnen, C.J.4
  • 43
    • 77954736319 scopus 로고    scopus 로고
    • Repeated mesenchymal stem cell treatment after neonatal hypoxia-ischemia has distinct effects on formation and maturation of new neurons and oligodendrocytes leading to restoration of damage, corticospinal motor tract activity, and sensorimotor function
    • van Velthoven CT, Kavelaars A, van Bel F, Heijnen CJ,. Repeated mesenchymal stem cell treatment after neonatal hypoxia-ischemia has distinct effects on formation and maturation of new neurons and oligodendrocytes leading to restoration of damage, corticospinal motor tract activity, and sensorimotor function. J Neurosci 2010; 30: 9603-9611.
    • (2010) J Neurosci , vol.30 , pp. 9603-9611
    • Van Velthoven, C.T.1    Kavelaars, A.2    Van Bel, F.3    Heijnen, C.J.4
  • 44
    • 77958450795 scopus 로고    scopus 로고
    • Nasal administration of stem cells: A promising novel route to treat neonatal ischemic brain damage
    • van Velthoven CT, Kavelaars A, van Bel F, Heijnen CJ,. Nasal administration of stem cells: a promising novel route to treat neonatal ischemic brain damage. Pediatr Res 2010; 68: 419-422.
    • (2010) Pediatr Res , vol.68 , pp. 419-422
    • Van Velthoven, C.T.1    Kavelaars, A.2    Van Bel, F.3    Heijnen, C.J.4
  • 45
    • 73449112945 scopus 로고    scopus 로고
    • Mesenchymal stem-cell transplantation for hypoxic-ischemic brain injury in neonatal rat model
    • Lee JA, Kim BI, Jo CH, et al. Mesenchymal stem-cell transplantation for hypoxic-ischemic brain injury in neonatal rat model. Pediatr Res 2010; 67: 42-46.
    • (2010) Pediatr Res , vol.67 , pp. 42-46
    • Lee, J.A.1    Kim, B.I.2    Jo, C.H.3
  • 46
    • 33744901079 scopus 로고    scopus 로고
    • Study on mesenchymal stem cells entering the brain through the blood-brain barrier [in Chinese]
    • Guan XQ, Yu JL, Li LQ, Liu GX,. Study on mesenchymal stem cells entering the brain through the blood-brain barrier [in Chinese]. Zhonghua Er Ke Za Zhi 2004; 42: 920-923.
    • (2004) Zhonghua Er Ke Za Zhi , vol.42 , pp. 920-923
    • Guan, X.Q.1    Yu, J.L.2    Li, L.Q.3    Liu, G.X.4
  • 47
    • 33646708298 scopus 로고    scopus 로고
    • Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells
    • Meier C, Middelanis J, Wasielewski B, et al. Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells. Pediatr Res 2006; 59: 244-249.
    • (2006) Pediatr Res , vol.59 , pp. 244-249
    • Meier, C.1    Middelanis, J.2    Wasielewski, B.3
  • 48
    • 79957818809 scopus 로고    scopus 로고
    • Human umbilical cord blood cells restore brain damage induced changes in rat somatosensory cortex
    • Geissler M, Dinse HR, Neuhoff S, et al. Human umbilical cord blood cells restore brain damage induced changes in rat somatosensory cortex. PloS One 2011; 6: e20194.
    • (2011) PloS One , vol.6
    • Geissler, M.1    Dinse, H.R.2    Neuhoff, S.3
  • 49
    • 77953932135 scopus 로고    scopus 로고
    • Mannitol facilitates neurotrophic factor up-regulation and behavioural recovery in neonatal hypoxic-ischaemic rats with human umbilical cord blood grafts
    • Yasuhara T, Hara K, Maki M, et al. Mannitol facilitates neurotrophic factor up-regulation and behavioural recovery in neonatal hypoxic-ischaemic rats with human umbilical cord blood grafts. J Cell Mol Med 2010; 14: 914-921.
    • (2010) J Cell Mol Med , vol.14 , pp. 914-921
    • Yasuhara, T.1    Hara, K.2    Maki, M.3
  • 50
    • 77949617579 scopus 로고    scopus 로고
    • Human cord blood transplantation in a neonatal rat model of hypoxic-ischemic brain damage: Functional outcome related to neuroprotection in the striatum
    • Pimentel-Coelho PM, Magalhaes ES, Lopes LM, et al. Human cord blood transplantation in a neonatal rat model of hypoxic-ischemic brain damage: functional outcome related to neuroprotection in the striatum. Stem Cells Dev 2010; 19: 351-358.
    • (2010) Stem Cells Dev , vol.19 , pp. 351-358
    • Pimentel-Coelho, P.M.1    Magalhaes, E.S.2    Lopes, L.M.3
  • 51
    • 67049155611 scopus 로고    scopus 로고
    • Hemispheric brain injury and behavioral deficits induced by severe neonatal hypoxia-ischemia in rats are not attenuated by intravenous administration of human umbilical cord blood cells
    • de Paula S, Vitola AS, Greggio S, et al. Hemispheric brain injury and behavioral deficits induced by severe neonatal hypoxia-ischemia in rats are not attenuated by intravenous administration of human umbilical cord blood cells. Pediatr Res 2009; 65: 631-635.
    • (2009) Pediatr Res , vol.65 , pp. 631-635
    • De Paula, S.1    Vitola, A.S.2    Greggio, S.3
  • 52
    • 20844453744 scopus 로고    scopus 로고
    • Transplantation of umbilical-cord blood in babies with infantile Krabbe's disease
    • Escolar ML, Poe MD, Provenzale JM, et al. Transplantation of umbilical-cord blood in babies with infantile Krabbe's disease. N Engl J Med 2005; 352: 2069-2081.
    • (2005) N Engl J Med , vol.352 , pp. 2069-2081
    • Escolar, M.L.1    Poe, M.D.2    Provenzale, J.M.3
  • 53
    • 56649118944 scopus 로고    scopus 로고
    • Human umbilical cord blood cells transfected with VEGF and L(1)CAM do not differentiate into neurons but transform into vascular endothelial cells and secrete neuro-trophic factors to support neuro-genesis-a novel approach in stem cell therapy
    • Rizvanov AA, Kiyasov AP, Gaziziov IM, et al. Human umbilical cord blood cells transfected with VEGF and L(1)CAM do not differentiate into neurons but transform into vascular endothelial cells and secrete neuro-trophic factors to support neuro-genesis-a novel approach in stem cell therapy. Neurochem Int 2008; 53: 389-394.
    • (2008) Neurochem Int , vol.53 , pp. 389-394
    • Rizvanov, A.A.1    Kiyasov, A.P.2    Gaziziov, I.M.3
  • 54
    • 79961066356 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation changes the gene expression profile of the neonatal ischemic brain
    • van Velthoven CT, Kavelaars A, van Bel F, Heijnen CJ,. Mesenchymal stem cell transplantation changes the gene expression profile of the neonatal ischemic brain. Brain Behav Immun 2011; 25: 1342-1348.
    • (2011) Brain Behav Immun , vol.25 , pp. 1342-1348
    • Van Velthoven, C.T.1    Kavelaars, A.2    Van Bel, F.3    Heijnen, C.J.4
  • 55
    • 72749121996 scopus 로고    scopus 로고
    • Optimizing the success of cell transplantation therapy for stroke
    • Bliss TM, Andres RH, Steinberg GK,. Optimizing the success of cell transplantation therapy for stroke. Neurobiol Dis 2010; 37: 275-283.
    • (2010) Neurobiol Dis , vol.37 , pp. 275-283
    • Bliss, T.M.1    Andres, R.H.2    Steinberg, G.K.3
  • 56
    • 45149103232 scopus 로고    scopus 로고
    • Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis
    • Kassis I, Grigoriadis N, Gowda-Kurkalli B, et al. Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis. Arch Neurol 2008; 65: 753-761.
    • (2008) Arch Neurol , vol.65 , pp. 753-761
    • Kassis, I.1    Grigoriadis, N.2    Gowda-Kurkalli, B.3
  • 57
    • 53849101373 scopus 로고    scopus 로고
    • Neural precursor cells inhibit multiple inflammatory signals
    • Fainstein N, Vaknin I, Einstein O, et al. Neural precursor cells inhibit multiple inflammatory signals. Mol Cell Neurosci 2008; 39: 335-341.
    • (2008) Mol Cell Neurosci , vol.39 , pp. 335-341
    • Fainstein, N.1    Vaknin, I.2    Einstein, O.3
  • 58
    • 37849053110 scopus 로고    scopus 로고
    • Immunomodulation by neural stem cells
    • Ben-Hur T,. Immunomodulation by neural stem cells. J Neurol Sci 2008; 265: 102-104.
    • (2008) J Neurol Sci , vol.265 , pp. 102-104
    • Ben-Hur, T.1
  • 59
    • 34147190318 scopus 로고    scopus 로고
    • Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression
    • Einstein O, Fainstein N, Vaknin I, et al. Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression. Ann Neurol 2007; 61: 209-218.
    • (2007) Ann Neurol , vol.61 , pp. 209-218
    • Einstein, O.1    Fainstein, N.2    Vaknin, I.3
  • 60
    • 4744358048 scopus 로고    scopus 로고
    • Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke
    • Borlongan CV, Hadman M, Sanberg CD, Sanberg PR,. Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke. Stroke 2004; 35: 2385-2389.
    • (2004) Stroke , vol.35 , pp. 2385-2389
    • Borlongan, C.V.1    Hadman, M.2    Sanberg, C.D.3    Sanberg, P.R.4
  • 61
    • 0042171674 scopus 로고    scopus 로고
    • Intravenous versus intrastriatal cord blood administration in a rodent model of stroke
    • Willing AE, Lixian J, Milliken M, et al. Intravenous versus intrastriatal cord blood administration in a rodent model of stroke. J Neurosci Res 2003; 73: 296-307.
    • (2003) J Neurosci Res , vol.73 , pp. 296-307
    • Willing, A.E.1    Lixian, J.2    Milliken, M.3
  • 62
    • 65549099571 scopus 로고    scopus 로고
    • Lack of migration and neurological benefits after infusion of umbilical cord blood cells in ischemic brain injury
    • Zawadzka M, Lukasiuk K, Machaj EK, et al. Lack of migration and neurological benefits after infusion of umbilical cord blood cells in ischemic brain injury. Acta Neurobiol Exp (Wars) 2009; 69: 46-51.
    • (2009) Acta Neurobiol Exp (Wars) , vol.69 , pp. 46-51
    • Zawadzka, M.1    Lukasiuk, K.2    MacHaj, E.K.3
  • 63
    • 33846294800 scopus 로고    scopus 로고
    • Human cord blood CD34+ cells and behavioral recovery following focal cerebral ischemia in rats
    • Nystedt J, Makinen S, Laine J, Jolkkonen J,. Human cord blood CD34+ cells and behavioral recovery following focal cerebral ischemia in rats. Acta Neurobiol Exp (Warsz) 2006; 66: 293-300.
    • (2006) Acta Neurobiol Exp (Warsz) , vol.66 , pp. 293-300
    • Nystedt, J.1    Makinen, S.2    Laine, J.3    Jolkkonen, J.4
  • 64
    • 33751159405 scopus 로고    scopus 로고
    • Human umbilical cord blood cells do not improve sensorimotor or cognitive outcome following transient middle cerebral artery occlusion in rats
    • Makinen S, Kekarainen T, Nystedt J, et al. Human umbilical cord blood cells do not improve sensorimotor or cognitive outcome following transient middle cerebral artery occlusion in rats. Brain Res 2006; 1123: 207-215.
    • (2006) Brain Res , vol.1123 , pp. 207-215
    • Makinen, S.1    Kekarainen, T.2    Nystedt, J.3
  • 65
    • 77957701000 scopus 로고    scopus 로고
    • Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair
    • Moodley Y, Ilancheran S, Samuel C, et al. Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair. Am J Respir Crit Care Med 2010; 182: 643-651.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 643-651
    • Moodley, Y.1    Ilancheran, S.2    Samuel, C.3
  • 66
    • 0037408202 scopus 로고    scopus 로고
    • Fetal responses to maternal and intra-amniotic lipopolysaccharide administration in sheep
    • Grigsby PL, Hirst JJ, Scheerlinck JP, et al. Fetal responses to maternal and intra-amniotic lipopolysaccharide administration in sheep. Biol Reprod 2003; 68: 1695-1702.
    • (2003) Biol Reprod , vol.68 , pp. 1695-1702
    • Grigsby, P.L.1    Hirst, J.J.2    Scheerlinck, J.P.3
  • 67
    • 33646358473 scopus 로고    scopus 로고
    • Chronic exposure to intra-amniotic lipopolysaccharide affects the ovine fetal brain
    • Nitsos I, Rees SM, Duncan J, et al. Chronic exposure to intra-amniotic lipopolysaccharide affects the ovine fetal brain. J Soc Gynecol Investig 2006; 13: 239-247.
    • (2006) J Soc Gynecol Investig , vol.13 , pp. 239-247
    • Nitsos, I.1    Rees, S.M.2    Duncan, J.3
  • 68
    • 0038054469 scopus 로고    scopus 로고
    • Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury
    • Lu P, Jones LL, Snyder EY, Tuszynski MH,. Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol 2003; 181: 115-129.
    • (2003) Exp Neurol , vol.181 , pp. 115-129
    • Lu, P.1    Jones, L.L.2    Snyder, E.Y.3    Tuszynski, M.H.4
  • 69
    • 33750816604 scopus 로고    scopus 로고
    • Committee on Understanding Premature Birth and Assuring Healthy Outcomes
    • Behrman R.E. Butler A.S. eds. Washington DC: Institute of Medicine of the National Academies, 346-397.
    • Committee on Understanding Premature Birth and Assuring Healthy Outcomes. In:, Behrman RE, Butler AS, eds. Preterm birth: causes, consequences, and prevention. Washington DC: Institute of Medicine of the National Academies, 2007, pp. 346-397.
    • (2007) Preterm Birth: Causes, Consequences, and Prevention
  • 70
    • 27744462939 scopus 로고    scopus 로고
    • Early brain injury in premature newborns detected with magnetic resonance imaging is associated with adverse early neurodevelopmental outcome
    • Miller SP, Ferriero DM, Leonard C, et al. Early brain injury in premature newborns detected with magnetic resonance imaging is associated with adverse early neurodevelopmental outcome. J Pediatr 2005; 147: 609-616.
    • (2005) J Pediatr , vol.147 , pp. 609-616
    • Miller, S.P.1    Ferriero, D.M.2    Leonard, C.3
  • 71
    • 21844469742 scopus 로고    scopus 로고
    • Selective vulnerability of preterm white matter to oxidative damage defined by F2-isoprostanes
    • Back SA, Luo NL, Mallinson RA, et al. Selective vulnerability of preterm white matter to oxidative damage defined by F2-isoprostanes. Ann Neurol 2005; 58: 108-120.
    • (2005) Ann Neurol , vol.58 , pp. 108-120
    • Back, S.A.1    Luo, N.L.2    Mallinson, R.A.3
  • 72
    • 80955142102 scopus 로고    scopus 로고
    • Precursor cell biology and the development of astrocyte transplantation therapies: Lessons from spinal cord injury
    • Noble M, Davies JE, Mayer-Proschel M, et al. Precursor cell biology and the development of astrocyte transplantation therapies: lessons from spinal cord injury. Neurotherapeutics 2011; 8: 677-693.
    • (2011) Neurotherapeutics , vol.8 , pp. 677-693
    • Noble, M.1    Davies, J.E.2    Mayer-Proschel, M.3
  • 73
    • 57149118216 scopus 로고    scopus 로고
    • Brain injury in premature infants: A complex amalgam of destructive and developmental disturbances
    • Volpe JJ,. Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol 2009; 8: 110-124.
    • (2009) Lancet Neurol , vol.8 , pp. 110-124
    • Volpe, J.J.1
  • 74
    • 84863393662 scopus 로고    scopus 로고
    • Arrested pre-oligodendrocyte maturation contributes to myelination failure in premature infants
    • DOI: 10.1002/ana.22627, 2011.
    • Buser JR, Maire J, Riddle A, et al. Arrested pre-oligodendrocyte maturation contributes to myelination failure in premature infants. Ann Neurol. DOI: 10.1002/ana.22627, 2011.
    • Ann Neurol
    • Buser, J.R.1    Maire, J.2    Riddle, A.3
  • 75
    • 59749101438 scopus 로고    scopus 로고
    • Animal models of perinatal hypoxic-ischemic brain damage
    • Yager JY, Ashwal S,. Animal models of perinatal hypoxic-ischemic brain damage. Pediatr Neurol 2009; 40: 156-167.
    • (2009) Pediatr Neurol , vol.40 , pp. 156-167
    • Yager, J.Y.1    Ashwal, S.2
  • 76
    • 33745018941 scopus 로고    scopus 로고
    • Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury
    • Park KI, Himes BT, Stieg PE, et al. Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: evidence from engraftment of neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury. Exp Neurol 2006; 199: 179-190.
    • (2006) Exp Neurol , vol.199 , pp. 179-190
    • Park, K.I.1    Himes, B.T.2    Stieg, P.E.3
  • 77
    • 38149048038 scopus 로고    scopus 로고
    • Transplantation of human fetal neural stem cells into cerebral ventricle of the neonatal rat following hypoxic-ischemic injury: Survival, migration and differentiation [in Chinese]
    • Qu SQ, Luan Z, Yin GC, et al. Transplantation of human fetal neural stem cells into cerebral ventricle of the neonatal rat following hypoxic-ischemic injury: survival, migration and differentiation [in Chinese]. Zhonghua Er Ke Za Zhi 2005; 43: 576-579.
    • (2005) Zhonghua Er Ke Za Zhi , vol.43 , pp. 576-579
    • Qu, S.Q.1    Luan, Z.2    Yin, G.C.3
  • 78
    • 77749267604 scopus 로고    scopus 로고
    • Intracerebral transplantation of mesenchymal stem cells derived from human umbilical cord blood alleviates hypoxic ischemic brain injury in rat neonates
    • Xia G, Hong X, Chen X, et al. Intracerebral transplantation of mesenchymal stem cells derived from human umbilical cord blood alleviates hypoxic ischemic brain injury in rat neonates. J Perinat Med 2010; 38: 215-221.
    • (2010) J Perinat Med , vol.38 , pp. 215-221
    • Xia, G.1    Hong, X.2    Chen, X.3


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