Systemic administration of human bone marrow-derived mesenchymal stromal cell extracellular vesicles ameliorates Aspergillus hyphal extract-induced allergic airway inflammation in immunocompetent mice

Stem Cells Translational Medicine

Volumn 4, Issue 11, 2015, Pages 1302-1316

  Cruz, Fernanda F ^a,b   Borg, Zachary D ^a   Goodwin, Meagan ^a   Sokocevic, Dino ^a   Wagner, Darcy E ^a   Coffey, Amy ^a   Antunes, Mariana ^a,b   Robinson, Kristen L ^a   Mitsialis, S Alex ^c,d   Kourembanas, Stella ^c,d   Thane, Kristen ^e   Hoffman, Andrew M ^e   McKenna, David H ^f   Rocco, Patricia R M ^b   Weiss, Daniel J ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e TUFTS UNIVERSITY   (United States)

^f UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Asthma; Conditioned media; EDCI; Extracellular vesicles; Mesenchymal stromal cells; Mouse

Indexed keywords

ALLERGIC AIRWAY INFLAMMATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPERGILLUS; CONTROLLED STUDY; CULTURE MEDIUM; EXOSOME; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; LUNG FUNCTION; MEDIASTINUM LYMPH NODE; MESENCHYMAL STROMA CELL; MOUSE; NONHUMAN; PNEUMONIA; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; ASTHMA; BONE MARROW CELL; CHEMICALLY INDUCED; CHEMISTRY; DRUG MIXTURE; FUNGUS HYPHAE; IMMUNOLOGY; MALE; MEMBRANE MICROPARTICLE; PATHOLOGY; TOXICITY;

DRUG MIXTURE;

ANIMALS; ASPERGILLUS; ASTHMA; BONE MARROW CELLS; CELL-DERIVED MICROPARTICLES; COMPLEX MIXTURES; HUMANS; HYPHAE; MALE; MESENCHYMAL STROMAL CELLS; MICE;

EID: 84945306718     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2014-0280     Document Type: Article

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