Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury

Journal of Neurosurgery

Volumn 122, Issue 4, 2015, Pages 856-867

  Zhang, Yanlu ^a   Chopp, Michael ^a,b   Meng, Yuling ^a   Katakowski, Mark ^a   Xin, Hongqi ^a   Mahmood, Asim ^a   Xiong, Ye ^a  

^a HENRY FORD HOSPITAL   (United States)

^b OAKLAND UNIVERSITY   (United States)

Author keywords

Angiogenesis; Exosomes; Functional recovery; Mesenchymal stromal cell; Neurogenesis; Traumatic brain injury

Indexed keywords

PHOSPHATE BUFFERED SALINE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITION; CONTROLLED STUDY; DENTATE GYRUS; ENDOTHELIUM CELL; EXOSOME; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MALE; MESENCHYMAL STROMA CELL; MORRIS WATER MAZE TEST; MULTIPOTENT STEM CELL; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR FUNCTION; SPATIAL LEARNING; THERAPY EFFECT; TRAUMATIC BRAIN INJURY; ANIMAL; BLOOD VESSEL; BRAIN INJURIES; CELL COUNT; CONVALESCENCE; INTRAVENOUS DRUG ADMINISTRATION; MAZE TEST; MESENCHYMAL STEM CELL TRANSPLANTATION; PATHOLOGY; PHYSIOLOGY; PLURIPOTENT STEM CELL; PROCEDURES; SENSATION; TRANSPLANTATION; WISTAR RAT;

ANIMALS; BLOOD VESSELS; BRAIN INJURIES; CELL COUNT; COGNITION; EXOSOMES; INJECTIONS, INTRAVENOUS; MALE; MAZE LEARNING; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; NEURONAL PLASTICITY; PLURIPOTENT STEM CELLS; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; SENSATION;

EID: 84964329540     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2014.11.JNS14770     Document Type: Article

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