The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation

Stem Cells

Volumn 29, Issue 4, 2011, Pages 725-735

  Jun, Du ^a,b   Garat, Chrystelle ^a,b   West, James ^c   Thorn, Nathalie ^d   Chow, Kelsey ^a   Cleaver, Timothy ^a,b   Sullivan, Timothy ^a,b   Torchia, Enrique C ^a   Childs, Christine ^a   Shade, Theodore ^a   Tadjali, Mehrdad ^e   Lara, Abigail ^a,b   Nozik Grayck, Eva ^f   Malkoski, Stephen ^a,b   Sorrentino, Brian ^e   Meyrick, Barbara ^c   Klemm, Dwight ^a,b   Rojas, Mauricio ^d   Wagner Jr , David H ^a,b   Majka, Susan M ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^f Children's Hospital Colorado   (United States)

Author keywords

Pulmonary fibrosis; Pulmonary hypertension; Resident lung mesenchymal stem cells; Stem cells

Indexed keywords

BLEOMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROTECTION; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; GENE EXPRESSION REGULATION; GRANULOCYTE; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG PARENCHYMA; LYMPHOCYTE PROLIFERATION; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PULMONARY HYPERTENSION; REGULATORY MECHANISM; TISSUE REGENERATION; TISSUE REPAIR;

ANIMALS; BLEOMYCIN; CELL PROLIFERATION; HYPERTENSION, PULMONARY; LUNG INJURY; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; PULMONARY FIBROSIS; T-LYMPHOCYTES;

MURINAE;

EID: 79953787534     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.604     Document Type: Article

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