Cord blood angiogenic progenitor cells are decreased in bronchopulmonary dysplasia

European Respiratory Journal

Volumn 40, Issue 6, 2012, Pages 1516-1522

  Baker, Christopher D ^a,b   Balasubramaniam, Vivek ^a,b   Mourani, Peter M ^a,b   Sontag, Marci K ^a   Black, Claudine P ^a   Ryan, Sharon L ^a   Abman, Steven H ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL COLORADO   (United States)

Author keywords

Bronchopulmonary dysplasia; Endothelial progenitor cells; Neonatal lung disease; Prematurity; Stem cells

Indexed keywords

ANGIOGENIC PROGENITOR CELL; ARTICLE; BIRTH WEIGHT; CELL COUNT; CIRCULATING PROGENITOR CELL; CONTROLLED STUDY; DISEASE SEVERITY; ENDOTHELIAL COLONY FORMING CELL; ENDOTHELIAL PROGENITOR CELL; FEMALE; GESTATIONAL AGE; HUMAN; HUMAN CELL; INFANT; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; MALE; NEWBORN; PERINATAL PERIOD; PREMATURITY; PRIORITY JOURNAL; RISK FACTOR; UMBILICAL CORD BLOOD;

BRONCHOPULMONARY DYSPLASIA; ENDOTHELIAL CELLS; FEMALE; FETAL BLOOD; FLOW CYTOMETRY; HUMANS; INFANT, NEWBORN; LEUKOCYTES, MONONUCLEAR; MALE; MATERNAL EXPOSURE; NEOVASCULARIZATION, PHYSIOLOGIC; PREGNANCY; RISK; RISK FACTORS; STEM CELLS; TREATMENT OUTCOME;

EID: 84864148261     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00017312     Document Type: Article

References (32)

1. Northway WH, Rosan RC, Porter DY. Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia. N Engl J Med 1967; 276: 357-368.
2. Jobe AH. The new bronchopulmonary dysplasia. Curr Opin Pediatr 2011; 23: 167-172.
3. Abman SH. Bronchopulmonary dysplasia: "a vascular hypothesis". Am J Respir Crit Care Med 2001; 164: 1755-1756.
4. Coalson JJ, Winter VT, Siler-Khodr T, et al. Neonatal chronic lung disease in extremely immature baboons. Am J Respir Crit Care Med 1999; 160: 1333-1346. (Pubitemid 29487478)
5. Baraldi E, Filippone M. Chronic lung disease after premature birth. N Engl J Med 2007; 357: 1946-1955. (Pubitemid 350074689)
6. Hansen AR, Barnés CM, Folkman J, et al. Maternal preeclampsia predicts the development of bronchopulmonary dysplasia. J Pediatr 2010; 156: 532-536.
7. Barker DJ. The intrauterine origins of cardiovascular and obstructive lung disease in adult life. The Marc Daniels Lecture 1990. J R Coll Physicians Lond 1991; 25: 129-133.
8. Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001; 163: 1723-1729. (Pubitemid 32578778)
9. Bhatt AJ, Pryhuber GS, Huyck H, et al. Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001; 164: 1971-1980. (Pubitemid 33152338)
10. Jakkula M, Le Cras TD, Gebb S, et al. Inhibition of angiogenesis decreases alveolarization in the developing rat lung. Am J Physiol Lung Cell Mol Physiol 2000; 279: L600-L607.
11. Janer J, Andersson S, Kajantie E, et al. Endostatin concentration in cord plasma predicts the development of bronchopulmonary dysplasia in very low birth weight infants. Pediatrics 2009; 123: 1142-1146.
12. Maynard SE. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 2003; 111: 649-658.
13. Flamme I, Frölich T, Risau W. Molecular mechanisms of vasculogenesis and embryonic angiogenesis. J Cell Physiol 1997; 173: 206-210. (Pubitemid 27481131)
14. Asahara T, Murohara T, Sullivan A, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997; 275: 964-967. (Pubitemid 27087709)
15. Balasubramaniam V, Mervis CF, Maxey AM, et al. Hyperoxia reduces bone marrow, circulating, and lung endothelial progenitor cells in the developing lung: implications for the pathogenesis of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 2007; 292: L1073-L1084. (Pubitemid 47084852)
16. Aslam M, Baveja R, Liang OD, et al. Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease. Am J Respir Crit Care Med 2009; 180: 1122-1130.
17. Van Haaften T, Byrne R, Bonnet S, et al. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med 2009; 1-55.
18. Balasubramaniam V, Ryan SL, Seedorf GJ, et al. Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice. Am J Physiol Lung Cell Mol Physiol 2010; 298: L315-L323.
19. Baker CD, Ryan SL, Ingram DA, et al. Endothelial colony-forming cells from preterm infants are increased and more susceptible to hyperoxia. Am J Respir Crit Care Med 2009; 180: 454-461.
20. Harris PA, Taylor R, Thielke R, et al. Research electronic data capture (REDCap) - a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 2009; 42: 377-381.
21. Estes ML, Mund JA, Ingram DA, et al. Identification of endothelial cells and progenitor cell subsets in human peripheral blood. Curr Protoc Cytom 2010; 9: 1-11.
22. Estes ML, Mund JA, Mead LE, et al. Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential. Cytometry A 2010; 77: 831-839.
23. Borghesi A, Massa M, Campanelli R, et al. Circulating endothelial progenitor cells in preterm infants with bronchopulmonary dysplasia. Am J Respir Crit Care Med 2009; 180: 540-546.
24. Ligi I, Simoncini S, Tellier E, et al. A switch toward angiostatic gene expression impairs the angiogenic properties of endothelial progenitor cells in low birth weight preterm infants. Blood 2011; 118: 1699-1709.
25. Hill JM, Zalos G, Halcox JP, et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003; 348: 593-600. (Pubitemid 36204953)
26. Ingram DA, Mead LE, Tanaka H, et al. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 2004; 104: 2752-2760. (Pubitemid 39434958)
27. Burnham EL, Taylor WR, Quyyumi AA, et al. Increased circulating endothelial progenitor cells are associated with survival in acute lung injury. Am J Respir Crit Care Med 2005; 172: 854-860. (Pubitemid 41369069)
28. Sieveking DP, Buckle A, Celermajer DS, et al. Strikingly different angiogenic properties of endothelial progenitor cell subpopulations: insights from a novel human angiogenesis assay. J Am Coll Cardiol 2008; 51: 660-668. (Pubitemid 351186872)
29. Yoder MC, Mead LE, Prater D, et al. Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood 2007; 109: 1801-1809. (Pubitemid 46348173)
30. Peichev M, Naiyer AJ, Pereira D, et al. Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors. Blood 2000; 95: 952-958. (Pubitemid 30062717)
31. Paviotti G, Fadini GP, Boscaro E, et al. Endothelial progenitor cells, bronchopulmonary dysplasia and other short-term outcomes of extremely preterm birth. Early Hum Dev 2011; 87: 461-465.
32. Acosta JC, Haas DM, Saha CK, et al. Gestational diabetes mellitus alters maternal and neonatal circulating endothelial progenitor cell subsets. Am J Obstet Gynecol 2011; 204: 254.e258-254.e215.