Mesenchymal stem cells for the prevention of bronchopulmonary dysplasia: Delivering the secretome

American Journal of Respiratory and Critical Care Medicine

Volumn 180, Issue 11, 2009, Pages 1039-1041

  Abman, Steven H ^a   Matthay, Michael A ^b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 6; KERATINOCYTE GROWTH FACTOR; SCATTER FACTOR; VASCULOTROPIN;

DISEASE COURSE; DISEASE EXACERBATION; EDITORIAL; HOSPITALIZATION; HUMAN; LUNG DYSPLASIA; LUNG FUNCTION; LUNG INJURY; LUNG VENTILATION; MESENCHYMAL STEM CELL TRANSPLANTATION; NEWBORN INTENSIVE CARE; NEWBORN MORBIDITY; NEWBORN MORTALITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; LUNG INJURY; MESENCHYMAL STEM CELLS; MICE; RATS;

EID: 72749096723     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200909-1330ED     Document Type: Editorial

References (16)

1. Northway WH Jr, Rosan RC, Porter DY. Pulmonary disease following respiratory therapy of hyaline membrane disease. N Engl J Med 1967;276:357-368.
2. Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001;163:1723-1729.
3. Hussain AN, Siddiqui NH, Stocker JT. Pathology of arrested acinar development in post-surfactant BPD. Hum Pathol 1998;29:710-717.
4. Ambalavanan N, Carlo WA, D'Angio CT, McDonald SA, Das A, Schendel D, Thorsen P, Higgins RD. Cytokines associated with bronchopulmonary dysplasia or death in extremely low birth weight infants. Pediatrics 2009;123:1132-1141.
5. Lee JW, Gupta N, Serikov V, Matthay MA. Potential application of mesenchymal stem cells in acute lung injury. Expert Opin Biol Ther 2009;9:1-12.
6. Rojas M, Xu J, Woods CR, Mora AL, Spears W, Roman J, Brigham KL. Bone marrow derived mesenchymal stem cells in repair of the injured lung. Am J Respir Cell Mol Biol 2005;33:145-152. (Pubitemid 41473051)
7. Ortiz LA, Gambelli F, McBride C, Gaupp D, Baddoo M, Kaminski N, Phinney DG. MSC engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibroproliferative effects. Proc Natl Acad Sci USA 2003;100:8407-8411. (Pubitemid 36842558)
8. Xu J, Woods CR, Mora AL, Joodi R, Brigham KL, Iyer S, Rojas M. Prevention of endotoxin-induced systemic response by bone marrowderived mesenchymal cells in mice. Am J Physiol Lung Cell Mol Physiol 2007;293:L131-L141. (Pubitemid 47080721)
9. Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA. Intrapulmonary delivery of bone marrow derived MSCs improves survival and attenuates endotoxin-induced acute lung injury. J Immunol 2007;179:1855-1863.
10. Lee RH, Pulin AA, Seo MJ, Kota DJ, Ylostalo J, Larson BL, Semrpun-Prieto L, Delafontaine P, Prockop DJ. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 2009;5:54-63.
11. Ortiz LA, Dutreil M, Fattman C, Pandey AC, Torres G, Go K, Phinney DG. Interleukin 1 receptor antagonist mediated the anti-inflammatory and antifibrotic effects of MSCs during acute lung injury. Proc Natl Acad Sci USA 2007;104:11002-11007. (Pubitemid 47175216)
12. Lee JW, Fang X, Gupta N, Serikov V, Matthay MA. Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the perfused human lung. Proc Natl Acad Sci USA 2009;106:16357-16362.
13. Hennrick KT, Keeton AG, Nanua S, Kijek TG, Goldsmith AM, Sajjam US, Bentley JK, Lama VN, Moore BB, Schumacher RE, et al. Lung cells from neonates show a mesenchymal stem cell phenotype. Am J Respir Crit Care Med 2007;175:1158-1164. (Pubitemid 46855457)
14. van Haaften T, Bryne R, Bonnet S, Rochefort GY, Akabutu J, Bouchentouf M, Rey-Parra GJ, Galipeu J, Haromy A, Eaton F, et al. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med 2009;180:1131-1142.
15. Aslam M, Baveja R, Liang OD, Fernandez-Gonzalez A, Lee C, Mitsialis SA, Kourembanas S. Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disesase. Am J Respir Crit Care Med 2009;180:1122-1130.
16. Bruno S, Grange C, Deregibus MC, Calogero RA, Saviozzi S, Collino F, Morando L, Busca A, Falda M, Bussolati B, et al. Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol 2009;20:1053-1067.