-
1
-
-
0020977755
-
Cellular mechanisms of immunologic tolerance
-
Nossal, G. J., Cellular mechanisms of immunologic tolerance. Annu. Rev. Immunol. 1983. 1: 33-62.
-
(1983)
Annu. Rev. Immunol.
, vol.1
, pp. 33-62
-
-
Nossal, G.J.1
-
2
-
-
42649138855
-
Thymus organogenesis
-
Rodewald, H.-R., Thymus organogenesis. Annu. Rev. Immunol. 2008. 26: 355-88..
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 355-388
-
-
Rodewald, H.-R.1
-
3
-
-
84861656218
-
Thymic epithelial cells: working class heroes for T cell development and repertoire selection
-
Anderson, G. and Takahama, Y., Thymic epithelial cells: working class heroes for T cell development and repertoire selection. Trends Immunol. 2012. 33: 256-263.
-
(2012)
Trends Immunol
, vol.33
, pp. 256-263
-
-
Anderson, G.1
Takahama, Y.2
-
4
-
-
34248598295
-
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
-
Aschenbrenner, K., D'Cruz, L. M., Vollmann, E. H., Hinterberger, M., Emmerich, J., Swee, L. K., Rolink, A. et al., Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. Nat. Immunol. 2007. 8: 351-358.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 351-358
-
-
Aschenbrenner, K.1
D'Cruz, L.M.2
Vollmann, E.H.3
Hinterberger, M.4
Emmerich, J.5
Swee, L.K.6
Rolink, A.7
-
5
-
-
84878662471
-
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development
-
Cowan, J. E., Parnell, S. M., Nakamura, K., Caamano, J. H., Lane, P. J. L., Jenkinson, E. J., Jenkinson, W. E. et al., The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development. J. Exp. Med. 2013. 210: 675-681.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 675-681
-
-
Cowan, J.E.1
Parnell, S.M.2
Nakamura, K.3
Caamano, J.H.4
Lane, P.J.L.5
Jenkinson, E.J.6
Jenkinson, W.E.7
-
6
-
-
84928581675
-
Immune tolerance, Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance
-
Yang, S., Fujikado, N., Kolodin, D., Benoist, C. and Mathis, D., Immune tolerance, Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance. Science 2015. 348: 589-594.
-
(2015)
Science
, vol.348
, pp. 589-594
-
-
Yang, S.1
Fujikado, N.2
Kolodin, D.3
Benoist, C.4
Mathis, D.5
-
7
-
-
0035171545
-
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
-
Derbinski, J., Schulte, A., Kyewski, B. and Klein, L., Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol. 2001. 2: 1032-1039.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1032-1039
-
-
Derbinski, J.1
Schulte, A.2
Kyewski, B.3
Klein, L.4
-
8
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson, M. S., Venanzi, E. S., Klein, L., Chen, Z., Berzins, S. P., Turley, S. J., von Boehmer, H. et al., Projection of an immunological self shadow within the thymus by the aire protein. Science. 2002. 298: 1395-1401.
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
von Boehmer, H.7
-
9
-
-
0037084784
-
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
-
Ramsey, C., Winqvist, O., Puhakka, L., Halonen, M., Moro, A., Kämpe, O., Eskelin, P. et al., Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum. Mol. Genet. 2002. 11: 397-409.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 397-409
-
-
Ramsey, C.1
Winqvist, O.2
Puhakka, L.3
Halonen, M.4
Moro, A.5
Kämpe, O.6
Eskelin, P.7
-
10
-
-
16944367194
-
Positional cloning of the APECED gene
-
Nagamine, K., Peterson, P., Scott, H. S., Jun, K., Minoshima, S., Heino, M., Krohn, K. J. E. et al., Positional cloning of the APECED gene. Nat. Genet. 1997. 17: 393-398.
-
(1997)
Nat. Genet.
, vol.17
, pp. 393-398
-
-
Nagamine, K.1
Peterson, P.2
Scott, H.S.3
Jun, K.4
Minoshima, S.5
Heino, M.6
Krohn, K.J.E.7
-
11
-
-
0025295238
-
Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients
-
Ahonen, P., Myllärniemi, S., Sipilä, I. and Perheentupa, J., Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients. N. Engl. J. Med. 1990. 322: 1829-1836.
-
(1990)
N. Engl. J. Med.
, vol.322
, pp. 1829-1836
-
-
Ahonen, P.1
Myllärniemi, S.2
Sipilä, I.3
Perheentupa, J.4
-
12
-
-
77951921063
-
Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis
-
Husebye, E. S. and Anderson, M. S., Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis. Immunity. 2010. 32: 479-487.
-
(2010)
Immunity
, vol.32
, pp. 479-487
-
-
Husebye, E.S.1
Anderson, M.S.2
-
13
-
-
0033590981
-
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla
-
Heino, M., Peterson, P., Kudoh, J., Nagamine, K., Lagerstedt, a., Ovod, V., Ranki, A. et al., Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem. Biophys. Res. Commun. 1999. 257: 821-825.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.257
, pp. 821-825
-
-
Heino, M.1
Peterson, P.2
Kudoh, J.3
Nagamine, K.4
Lagerstedt, a5
Ovod, V.6
Ranki, A.7
-
14
-
-
0035147378
-
Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)
-
Halonen, M., Pelto-Huikko, M., Eskelin, P., Peltonen, L., Ulmanen, I. and Kolmer, M., Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED). J. Histochem. Cytochem. 2001. 49: 197-208.
-
(2001)
J. Histochem. Cytochem.
, vol.49
, pp. 197-208
-
-
Halonen, M.1
Pelto-Huikko, M.2
Eskelin, P.3
Peltonen, L.4
Ulmanen, I.5
Kolmer, M.6
-
15
-
-
49449093723
-
Deletional tolerance mediated by extrathymic Aire-expressing cells
-
Gardner, J. M., Devoss, J. J., Friedman, R. S., Wong, D. J., Tan, Y. X., Zhou, X., Johannes, K. P. et al., Deletional tolerance mediated by extrathymic Aire-expressing cells. Science. 2008. 321: 843-847.
-
(2008)
Science
, vol.321
, pp. 843-847
-
-
Gardner, J.M.1
Devoss, J.J.2
Friedman, R.S.3
Wong, D.J.4
Tan, Y.X.5
Zhou, X.6
Johannes, K.P.7
-
16
-
-
84937631527
-
Thymic B cells are licensed to present self antigens for central T cell tolerance induction
-
Yamano, T., Nedjic, J., Hinterberger, M., Steinert, M., Koser, S., Pinto, S., Gerdes, N. et al., Thymic B cells are licensed to present self antigens for central T cell tolerance induction. Immunity 2015. 42: 1048-1061.
-
(2015)
Immunity
, vol.42
, pp. 1048-1061
-
-
Yamano, T.1
Nedjic, J.2
Hinterberger, M.3
Steinert, M.4
Koser, S.5
Pinto, S.6
Gerdes, N.7
-
17
-
-
40749106576
-
Expression of Aire and the early wave of apoptosis in spermatogenesis
-
Schaller, C. E., Wang, C. L., Beck-Engeser, G., Goss, L., Scott, H. S., Anderson, M. S. and Wabl, M., Expression of Aire and the early wave of apoptosis in spermatogenesis. J. Immunol. 2008. 180: 1338-1343.
-
(2008)
J. Immunol.
, vol.180
, pp. 1338-1343
-
-
Schaller, C.E.1
Wang, C.L.2
Beck-Engeser, G.3
Goss, L.4
Scott, H.S.5
Anderson, M.S.6
Wabl, M.7
-
18
-
-
0033939699
-
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
-
Heino, M., Peterson, P., Sillanpää, N., Guérin, S., Wu, L., Anderson, G., Scott, H. S. et al., RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse. Eur. J. Immunol. 2000. 30: 1884-1893.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1884-1893
-
-
Heino, M.1
Peterson, P.2
Sillanpää, N.3
Guérin, S.4
Wu, L.5
Anderson, G.6
Scott, H.S.7
-
19
-
-
77952302980
-
Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation
-
Nishikawa, Y., Hirota, F., Yano, M., Kitajima, H., Miyazaki, J., Kawamoto, H., Mouri, Y. et al., Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation. J. Exp. Med. 2010. 207: 963-971.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 963-971
-
-
Nishikawa, Y.1
Hirota, F.2
Yano, M.3
Kitajima, H.4
Miyazaki, J.5
Kawamoto, H.6
Mouri, Y.7
-
20
-
-
56749161528
-
Transcriptional regulation by AIRE: molecular mechanisms of central tolerance
-
Peterson, P., Org, T. and Rebane, A., Transcriptional regulation by AIRE: molecular mechanisms of central tolerance. Nat. Rev. Immunol. 2008. 8: 948-957.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 948-957
-
-
Peterson, P.1
Org, T.2
Rebane, A.3
-
22
-
-
84891339888
-
The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein
-
Perniola, R. and Musco, G., The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein. Biochim. Biophys. Acta - Mol. Basis Dis. 2014. 1842: 326-337.
-
(2014)
Biochim. Biophys. Acta - Mol. Basis Dis.
, vol.1842
, pp. 326-337
-
-
Perniola, R.1
Musco, G.2
-
23
-
-
38349110211
-
AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity
-
Ferguson, B. J., Alexander, C., Rossi, S. W., Liiv, I., Rebane, A., Worth, C. L., Wong, J. et al., AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity. J. Biol. Chem. 2008. 283: 1723-1731.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1723-1731
-
-
Ferguson, B.J.1
Alexander, C.2
Rossi, S.W.3
Liiv, I.4
Rebane, A.5
Worth, C.L.6
Wong, J.7
-
24
-
-
56749174388
-
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity
-
Koh, A. S., Kuo, A. J., Park, S. Y., Cheung, P., Abramson, J., Bua, D., Carney, D. et al., Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. Proc. Natl. Acad. Sci. USA 2008. 105: 15878-15883.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15878-15883
-
-
Koh, A.S.1
Kuo, A.J.2
Park, S.Y.3
Cheung, P.4
Abramson, J.5
Bua, D.6
Carney, D.7
-
25
-
-
45849137524
-
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
-
Org, T., Chignola, F., Hetényi, C., Gaetani, M., Rebane, A., Liiv, I., Maran, U. et al., The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression. EMBO Rep. 2008. 9: 370-376.
-
(2008)
EMBO Rep
, vol.9
, pp. 370-376
-
-
Org, T.1
Chignola, F.2
Hetényi, C.3
Gaetani, M.4
Rebane, A.5
Liiv, I.6
Maran, U.7
-
26
-
-
38049026826
-
DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity
-
Liiv, I., Rebane, A., Org, T., Saare, M., Maslovskaja, J., Kisand, K., Juronen, E. et al., DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity. Biochim. Biophys. Acta. 2008. 1783: 74-83.
-
(2008)
Biochim. Biophys. Acta.
, vol.1783
, pp. 74-83
-
-
Liiv, I.1
Rebane, A.2
Org, T.3
Saare, M.4
Maslovskaja, J.5
Kisand, K.6
Juronen, E.7
-
27
-
-
84873107959
-
Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance
-
Yang, S., Bansal, K., Lopes, J., Benoist, C. and Mathis, D., Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance. Proc. Natl. Acad. Sci. USA 2013. 110: 1833-1838.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 1833-1838
-
-
Yang, S.1
Bansal, K.2
Lopes, J.3
Benoist, C.4
Mathis, D.5
-
28
-
-
77951227124
-
DAXX is a new AIRE-interacting protein
-
Meloni, A., Meloni, A., Fiorillo, E., Corda, D., Incani, F., Serra, M. L., Contini, A. et al., DAXX is a new AIRE-interacting protein. J. Biol. Chem. 2010. 285: 13012-13021.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 13012-13021
-
-
Meloni, A.1
Meloni, A.2
Fiorillo, E.3
Corda, D.4
Incani, F.5
Serra, M.L.6
Contini, A.7
-
29
-
-
84922105556
-
The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling
-
Kao, W.-P., Yang, C.-Y., Su, T.-W., Wang, Y.-T., Lo, Y.-C. and Lin, S.-C., The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling. Apoptosis. 2015. 20: 174-195.
-
(2015)
Apoptosis.
, vol.20
, pp. 174-195
-
-
Kao, W.-P.1
Yang, C.-Y.2
Su, T.-W.3
Wang, Y.-T.4
Lo, Y.-C.5
Lin, S.-C.6
-
30
-
-
0038824426
-
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein
-
Pitkänen, J., Doucas, V., Sternsdorf, T., Nakajima, T., Aratani, S., Jensen, K., Will, H. et al., The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J. Biol. Chem. 2000. 275: 16802-16809.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16802-16809
-
-
Pitkänen, J.1
Doucas, V.2
Sternsdorf, T.3
Nakajima, T.4
Aratani, S.5
Jensen, K.6
Will, H.7
-
31
-
-
0035798665
-
The autoimmune regulator (AIRE) is a DNA-binding protein
-
Kumar, P. G., Laloraya, M., Wang, C. Y., Ruan, Q. G., Davoodi-Semiromi, A., Kao, K. J. and She, J. X., The autoimmune regulator (AIRE) is a DNA-binding protein. J. Biol. Chem. 2001. 276: 41357-41364.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41357-41364
-
-
Kumar, P.G.1
Laloraya, M.2
Wang, C.Y.3
Ruan, Q.G.4
Davoodi-Semiromi, A.5
Kao, K.J.6
She, J.X.7
-
32
-
-
84894431935
-
The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance
-
Waterfield, M., Khan, I. S., Cortez, J. T., Fan, U., Metzger, T., Greer, A., Fasano, K. et al., The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. Nat. Immunol. 2014. 15: 258-265.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 258-265
-
-
Waterfield, M.1
Khan, I.S.2
Cortez, J.T.3
Fan, U.4
Metzger, T.5
Greer, A.6
Fasano, K.7
-
33
-
-
0034749749
-
A novel mutation of the autoimmune regulator gene in an Italian kindred with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, acting in a dominant fashion and strongly cosegregating with hypothyroid autoimmune thyroiditis
-
Cetani, F., Barbesino, G., Borsari, S., Pardi, E., Cianferotti, L., Pinchera, A. and Marcocci, C., A novel mutation of the autoimmune regulator gene in an Italian kindred with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, acting in a dominant fashion and strongly cosegregating with hypothyroid autoimmune thyroiditis. J. Clin. Endocrinol. Metab. 2001. 86: 4747-4752.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 4747-4752
-
-
Cetani, F.1
Barbesino, G.2
Borsari, S.3
Pardi, E.4
Cianferotti, L.5
Pinchera, A.6
Marcocci, C.7
-
34
-
-
43049128502
-
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
-
Su, M. A., Giang, K., Zumer, K., Jiang, H., Oven, I., Rinn, J. L., Devoss, J. J. et al., Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. J. Clin. Invest. 2008. 118: 1712-1726.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1712-1726
-
-
Su, M.A.1
Giang, K.2
Zumer, K.3
Jiang, H.4
Oven, I.5
Rinn, J.L.6
Devoss, J.J.7
-
35
-
-
84937598338
-
Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases
-
Oftedal, B. E., Hellesen, A., Erichsen, M. M., Bratland, E., Vardi, A., Perheentupa, J., Kemp, E. H. et al., Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases. Immunity 2015. 42: 1185-1196.
-
(2015)
Immunity
, vol.42
, pp. 1185-1196
-
-
Oftedal, B.E.1
Hellesen, A.2
Erichsen, M.M.3
Bratland, E.4
Vardi, A.5
Perheentupa, J.6
Kemp, E.H.7
-
36
-
-
0038486459
-
Localization of the APECED protein in distinct nuclear structures
-
Björses, P., Pelto-Huikko, M., Kaukonen, J., Aaltonen, J., Peltonen, L. and Ulmanen, I., Localization of the APECED protein in distinct nuclear structures. Hum. Mol. Genet. 1999. 8: 259-266.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 259-266
-
-
Björses, P.1
Pelto-Huikko, M.2
Kaukonen, J.3
Aaltonen, J.4
Peltonen, L.5
Ulmanen, I.6
-
37
-
-
33645037895
-
The monopartite nuclear localization signal of autoimmune regulator mediates its nuclear import and interaction with multiple importin alpha molecules
-
Ilmarinen, T., Melén, K., Kangas, H., Julkunen, I., Ulmanen, I. and Eskelin, P., The monopartite nuclear localization signal of autoimmune regulator mediates its nuclear import and interaction with multiple importin alpha molecules. FEBS J. 2006. 273: 315-324.
-
(2006)
FEBS J
, vol.273
, pp. 315-324
-
-
Ilmarinen, T.1
Melén, K.2
Kangas, H.3
Julkunen, I.4
Ulmanen, I.5
Eskelin, P.6
-
38
-
-
40149100294
-
Evolutionarily conserved and divergent regions of the autoimmune regulator (Aire) gene: a comparative analysis
-
Saltis, M., Criscitiello, M. F., Ohta, Y., Keefe, M., Trede, N. S., Goitsuka, R. and Flajnik, M. F., Evolutionarily conserved and divergent regions of the autoimmune regulator (Aire) gene: a comparative analysis. Immunogenetics. 2008. 60: 105-114.
-
(2008)
Immunogenetics
, vol.60
, pp. 105-114
-
-
Saltis, M.1
Criscitiello, M.F.2
Ohta, Y.3
Keefe, M.4
Trede, N.S.5
Goitsuka, R.6
Flajnik, M.F.7
-
39
-
-
84961289097
-
The nuclear pore complex-structure and function at a glance
-
Kabachinski, G. and Schwartz, T. U., The nuclear pore complex-structure and function at a glance. J. Cell Sci. 2015. 128: 423-429.
-
(2015)
J. Cell Sci.
, vol.128
, pp. 423-429
-
-
Kabachinski, G.1
Schwartz, T.U.2
-
40
-
-
73149115486
-
Aire's partners in the molecular control of immunological tolerance
-
Abramson, J., Giraud, M., Benoist, C. and Mathis, D., Aire's partners in the molecular control of immunological tolerance. Cell. 2010. 140: 123-135.
-
(2010)
Cell
, vol.140
, pp. 123-135
-
-
Abramson, J.1
Giraud, M.2
Benoist, C.3
Mathis, D.4
-
41
-
-
84871186320
-
AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome
-
Gaetani, M., Matafora, V., Saare, M., Spiliotopoulos, D., Mollica, L., Quilici, G., Chignola, F. et al., AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome. Nucleic Acids Res. 2012. 40: 11756-11768.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 11756-11768
-
-
Gaetani, M.1
Matafora, V.2
Saare, M.3
Spiliotopoulos, D.4
Mollica, L.5
Quilici, G.6
Chignola, F.7
-
42
-
-
4043130957
-
Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner
-
Akiyoshi, H., Hatakeyama, S., Pitkänen, J., Mouri, Y., Doucas, V., Kudoh, J., Tsurugaya, K. et al., Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner. J. Biol. Chem. 2004. 279: 33984-33991.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33984-33991
-
-
Akiyoshi, H.1
Hatakeyama, S.2
Pitkänen, J.3
Mouri, Y.4
Doucas, V.5
Kudoh, J.6
Tsurugaya, K.7
-
43
-
-
0242536432
-
Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein
-
Björses, P., Halonen, M., Palvimo, J. J., Kolmer, M., Aaltonen, J., Ellonen, P., Perheentupa, J. et al., Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein. Am. J. Hum. Genet. 2000. 66: 378-392.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 378-392
-
-
Björses, P.1
Halonen, M.2
Palvimo, J.J.3
Kolmer, M.4
Aaltonen, J.5
Ellonen, P.6
Perheentupa, J.7
-
44
-
-
12144291655
-
APECED-causing mutations in AIRE reveal the functional domains of the protein
-
Halonen, M., Kangas, H., Rüppell, T., Ilmarinen, T., Ollila, J., Kolmer, M., Vihinen, M. et al., APECED-causing mutations in AIRE reveal the functional domains of the protein. Hum. Mutat. 2004. 23: 245-257.
-
(2004)
Hum. Mutat.
, vol.23
, pp. 245-257
-
-
Halonen, M.1
Kangas, H.2
Rüppell, T.3
Ilmarinen, T.4
Ollila, J.5
Kolmer, M.6
Vihinen, M.7
-
45
-
-
27944494841
-
AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix
-
Tao, Y., Kupfer, R., Stewart, B. J., Williams-Skipp, C., Crowell, C. K., Patel, D. D., Sain, S. et al., AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix. Mol. Immunol. 2006. 43: 335-345.
-
(2006)
Mol. Immunol.
, vol.43
, pp. 335-345
-
-
Tao, Y.1
Kupfer, R.2
Stewart, B.J.3
Williams-Skipp, C.4
Crowell, C.K.5
Patel, D.D.6
Sain, S.7
-
46
-
-
84904161796
-
A requiem to the nuclear matrix: from a controversial concept to 3D organization of the nucleus
-
Razin, S V., Iarovaia, O V. and Vassetzky, Y. S., A requiem to the nuclear matrix: from a controversial concept to 3D organization of the nucleus. Chromosoma 2014. 123: 217-224.
-
(2014)
Chromosoma
, vol.123
, pp. 217-224
-
-
Razin, S.V.1
Iarovaia, O.V.2
Vassetzky, Y.S.3
-
47
-
-
68049110635
-
Proteome analysis of human nuclear insoluble fractions
-
Takata, H., Nishijima, H., Ogura, S.-I., Sakaguchi, T., Bubulya, P. A., Mochizuki, T. and Shibahara, K.-I., Proteome analysis of human nuclear insoluble fractions. Genes Cells 2009. 14: 975-990.
-
(2009)
Genes Cells
, vol.14
, pp. 975-990
-
-
Takata, H.1
Nishijima, H.2
Ogura, S.-I.3
Sakaguchi, T.4
Bubulya, P.A.5
Mochizuki, T.6
Shibahara, K.-I.7
-
48
-
-
77956964856
-
A mini review of MAR-binding proteins
-
Wang, T.-Y., Han, Z.-M., Chai, Y.-R. and Zhang, J.-H., A mini review of MAR-binding proteins. Mol. Biol. Rep. 2010. 37: 3553-3560.
-
(2010)
Mol. Biol. Rep.
, vol.37
, pp. 3553-3560
-
-
Wang, T.-Y.1
Han, Z.-M.2
Chai, Y.-R.3
Zhang, J.-H.4
-
49
-
-
18844362882
-
Chromosomal clustering of genes controlled by the aire transcription factor
-
Johnnidis, J. B., Venanzi, E. S., Taxman, D. J., Ting, J. P.-Y., Benoist, C. O. and Mathis, D. J., Chromosomal clustering of genes controlled by the aire transcription factor. Proc. Natl. Acad. Sci. USA 2005. 102: 7233-7238.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7233-7238
-
-
Johnnidis, J.B.1
Venanzi, E.S.2
Taxman, D.J.3
Ting, J.P.-Y.4
Benoist, C.O.5
Mathis, D.J.6
-
50
-
-
84913594338
-
Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia
-
Sansom, S. N., Shikama-Dorn, N., Zhanybekova, S., Nusspaumer, G., Macaulay, I. C., Deadman, M. E., Heger, A. et al., Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia. Genome Res. 2014. 24: 1918-1931.
-
(2014)
Genome Res
, vol.24
, pp. 1918-1931
-
-
Sansom, S.N.1
Shikama-Dorn, N.2
Zhanybekova, S.3
Nusspaumer, G.4
Macaulay, I.C.5
Deadman, M.E.6
Heger, A.7
-
51
-
-
11844254540
-
Mapping DNA-binding domains of the autoimmune regulator protein
-
Purohit, S., Kumar, P. G., Laloraya, M. and She, J.-X., Mapping DNA-binding domains of the autoimmune regulator protein. Biochem. Biophys. Res. Commun. 2005. 327: 939-944.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.327
, pp. 939-944
-
-
Purohit, S.1
Kumar, P.G.2
Laloraya, M.3
She, J.-X.4
-
52
-
-
34249811200
-
The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function
-
Ruan, Q.-G., Tung, K., Eisenman, D., Setiady, Y., Eckenrode, S., Yi, B., Purohit, S. et al., The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function. J. Immunol. 2007. 178: 7173-7180.
-
(2007)
J. Immunol.
, vol.178
, pp. 7173-7180
-
-
Ruan, Q.-G.1
Tung, K.2
Eisenman, D.3
Setiady, Y.4
Eckenrode, S.5
Yi, B.6
Purohit, S.7
-
53
-
-
0034957535
-
The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation
-
Bottomley, M. J., Collard, M. W., Huggenvik, J. I., Liu, Z., Gibson, T. J. and Sattler, M., The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation. Nat. Struct. Biol. 2001. 8: 626-633.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 626-633
-
-
Bottomley, M.J.1
Collard, M.W.2
Huggenvik, J.I.3
Liu, Z.4
Gibson, T.J.5
Sattler, M.6
-
54
-
-
0038309923
-
Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions
-
Surdo, PLo., Bottomley, M. J., Sattler, M. and Scheffzek, K., Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions. Mol. Endocrinol. 2003. 17: 1283-1295.
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1283-1295
-
-
Surdo, PL.1
Bottomley, M.J.2
Sattler, M.3
Scheffzek, K.4
-
55
-
-
70450192681
-
AIRE activated tissue specific genes have histone modifications associated with inactive chromatin
-
Org, T., Rebane, A., Kisand, K., Laan, M., Haljasorg, U., Andreson, R. and Peterson, P., AIRE activated tissue specific genes have histone modifications associated with inactive chromatin. Hum. Mol. Genet. 2009. 18: 4699-4710.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4699-4710
-
-
Org, T.1
Rebane, A.2
Kisand, K.3
Laan, M.4
Haljasorg, U.5
Andreson, R.6
Peterson, P.7
-
56
-
-
84855995571
-
Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells
-
Giraud, M., Yoshida, H., Abramson, J., Rahl, P. B., Young, R. A., Mathis, D. and Benoist, C., Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells. Proc. Natl. Acad. Sci. USA 2012. 109: 535-540.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 535-540
-
-
Giraud, M.1
Yoshida, H.2
Abramson, J.3
Rahl, P.B.4
Young, R.A.5
Mathis, D.6
Benoist, C.7
-
57
-
-
84923780299
-
Getting up to speed with transcription elongation by RNA polymerase I. I
-
Jonkers, I. and Lis, J. T., Getting up to speed with transcription elongation by RNA polymerase I. I. Nat. Rev. Mol. Cell Biol. 2015. 16: 167-177.
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 167-177
-
-
Jonkers, I.1
Lis, J.T.2
-
58
-
-
52949125608
-
Transcriptional impact of Aire varies with cell type
-
Guerau-de-Arellano, M., Mathis, D. and Benoist, C., Transcriptional impact of Aire varies with cell type. Proc. Natl. Acad. Sci. USA 2008. 105: 14011-14016.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14011-14016
-
-
Guerau-de-Arellano, M.1
Mathis, D.2
Benoist, C.3
-
59
-
-
37549060329
-
AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells
-
Oven, I., Brdicková, N., Kohoutek, J., Vaupotic, T., Narat, M. and Peterlin, B. M., AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells. Mol. Cell. Biol. 2007. 27: 8815-8823.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 8815-8823
-
-
Oven, I.1
Brdicková, N.2
Kohoutek, J.3
Vaupotic, T.4
Narat, M.5
Peterlin, B.M.6
-
60
-
-
84893370802
-
An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription
-
Giraud, M., Jmari, N., Du, L., Carallis, F., Nieland, T. J. F., Perez-Campo, F. M., Bensaude, O. et al., An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription. Proc. Natl. Acad. Sci. USA 2014. 111: 1491-1496.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 1491-1496
-
-
Giraud, M.1
Jmari, N.2
Du, L.3
Carallis, F.4
Nieland, T.J.F.5
Perez-Campo, F.M.6
Bensaude, O.7
-
61
-
-
84938921551
-
Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells
-
Yoshida, H., Bansal, K., Schaefer, U., Chapman, T., Rioja, I., Proekt, I., Anderson, M. S. et al., Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells. Proc. Natl. Acad. Sci. USA 2015. DOI: 10.1073/pnas.1512081112.
-
(2015)
Proc. Natl. Acad. Sci. USA
-
-
Yoshida, H.1
Bansal, K.2
Schaefer, U.3
Chapman, T.4
Rioja, I.5
Proekt, I.6
Anderson, M.S.7
-
62
-
-
23744514308
-
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
-
Jang, M. K., Mochizuki, K., Zhou, M., Jeong, H.-S., Brady, J. N. and Ozato, K., The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. Mol. Cell. 2005. 19: 523-534.
-
(2005)
Mol. Cell.
, vol.19
, pp. 523-534
-
-
Jang, M.K.1
Mochizuki, K.2
Zhou, M.3
Jeong, H.-S.4
Brady, J.N.5
Ozato, K.6
-
63
-
-
84925556593
-
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones
-
Kanno, T., Kanno, Y., LeRoy, G., Campos, E., Sun, H.-W., Brooks, S. R., Vahedi, G. et al., BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. Nat. Struct. Mol. Biol. 2014. 21: 1047-1057.
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 1047-1057
-
-
Kanno, T.1
Kanno, Y.2
LeRoy, G.3
Campos, E.4
Sun, H.-W.5
Brooks, S.R.6
Vahedi, G.7
-
64
-
-
84961574727
-
A genetically encoded FRET probe to detect intranucleosomal histone H3K9 or H3K14 acetylation using BRD4, a BET family member
-
Nakaoka, S., Sasaki, K., Ito, A., Nakao, Y. and Yoshida, M., A genetically encoded FRET probe to detect intranucleosomal histone H3K9 or H3K14 acetylation using BRD4, a BET family member. ACS Chem. Biol. 2015. DOI: 10.1021/cb501046t.
-
(2015)
ACS Chem. Biol.
-
-
Nakaoka, S.1
Sasaki, K.2
Ito, A.3
Nakao, Y.4
Yoshida, M.5
-
65
-
-
84861325370
-
Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes
-
Žumer, K., Low, A. K., Jiang, H., Saksela, K. and Peterlin, B. M., Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes. Mol. Cell. Biol. 2012. 32: 1354-1362.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 1354-1362
-
-
Žumer, K.1
Low, A.K.2
Jiang, H.3
Saksela, K.4
Peterlin, B.M.5
-
66
-
-
84942619984
-
PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity
-
e5.
-
Mathieu, A.-L., Verronese, E., Rice, G. I., Fouyssac, F., Bertrand, Y., Picard, C., Chansel, M. et al., PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity. J. Allergy Clin. Immunol. 2015. 135: 1578-1588.e5.
-
(2015)
J. Allergy Clin. Immunol.
, vol.135
, pp. 1578-1588
-
-
Mathieu, A.-L.1
Verronese, E.2
Rice, G.I.3
Fouyssac, F.4
Bertrand, Y.5
Picard, C.6
Chansel, M.7
-
67
-
-
65549111779
-
Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes
-
Callén, E., Jankovic, M., Wong, N., Zha, S., Chen, H.-T., Difilippantonio, S., Di Virgilio, M. et al., Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes. Mol. Cell. 2009. 34: 285-297.
-
(2009)
Mol. Cell.
, vol.34
, pp. 285-297
-
-
Callén, E.1
Jankovic, M.2
Wong, N.3
Zha, S.4
Chen, H.-T.5
Difilippantonio, S.6
Di Virgilio, M.7
-
68
-
-
33746601439
-
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
-
Ziv, Y., Bielopolski, D., Galanty, Y., Lukas, C., Taya, Y., Schultz, D. C., Lukas, J. et al., Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway. Nat. Cell Biol. 2006. 8: 870-876.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 870-876
-
-
Ziv, Y.1
Bielopolski, D.2
Galanty, Y.3
Lukas, C.4
Taya, Y.5
Schultz, D.C.6
Lukas, J.7
-
69
-
-
41549112501
-
FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16
-
Heo, K., Kim, H., Choi, S. H., Choi, J., Kim, K., Gu, J., Lieber, M. R. et al., FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16. Mol. Cell. 2008. 30(1): 86-97.
-
(2008)
Mol. Cell.
, vol.30
, Issue.1
, pp. 86-97
-
-
Heo, K.1
Kim, H.2
Choi, S.H.3
Choi, J.4
Kim, K.5
Gu, J.6
Lieber, M.R.7
-
70
-
-
84882585259
-
Enhanced chromatin dynamics by FACT promotes transcriptional restart after UV-induced DNA damage
-
Dinant, C., Ampatziadis-Michailidis, G., Lans, H., Tresini, M., Lagarou, A., Grosbart, M., Theil, A. F. et al., Enhanced chromatin dynamics by FACT promotes transcriptional restart after UV-induced DNA damage. Mol. Cell. 2013. 51: 469-479.
-
(2013)
Mol. Cell.
, vol.51
, pp. 469-479
-
-
Dinant, C.1
Ampatziadis-Michailidis, G.2
Lans, H.3
Tresini, M.4
Lagarou, A.5
Grosbart, M.6
Theil, A.F.7
-
71
-
-
77955069195
-
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
-
Haffner, M. C., Aryee, M. J., Toubaji, A., Esopi, D. M., Albadine, R., Gurel, B., Isaacs, W. B. et al., Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nat. Genet. 2010. 42: 668-675.
-
(2010)
Nat. Genet.
, vol.42
, pp. 668-675
-
-
Haffner, M.C.1
Aryee, M.J.2
Toubaji, A.3
Esopi, D.M.4
Albadine, R.5
Gurel, B.6
Isaacs, W.B.7
-
72
-
-
33745255099
-
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription
-
Ju, B.-G., Lunyak, V V., Perissi, V., Garcia-Bassets, I., Rose, D. W., Glass, C. K. and Rosenfeld, M. G., A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science 2006. 312: 1798-1802.
-
(2006)
Science
, vol.312
, pp. 1798-1802
-
-
Ju, B.-G.1
Lunyak, V.V.2
Perissi, V.3
Garcia-Bassets, I.4
Rose, D.W.5
Glass, C.K.6
Rosenfeld, M.G.7
-
73
-
-
71249101060
-
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
-
Lin, C., Yang, L., Tanasa, B., Hutt, K., Ju, B., Ohgi, K., Zhang, J. et al., Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell. 2009. 139: 1069-1083.
-
(2009)
Cell
, vol.139
, pp. 1069-1083
-
-
Lin, C.1
Yang, L.2
Tanasa, B.3
Hutt, K.4
Ju, B.5
Ohgi, K.6
Zhang, J.7
-
74
-
-
15844390393
-
A human RNA polymerase II complex associated with SRB and DNA-repair proteins
-
Maldonado, E., Shiekhattar, R., Sheldon, M., Cho, H., Drapkin, R., Rickert, P., Lees, E. et al., A human RNA polymerase II complex associated with SRB and DNA-repair proteins. Nature 1996. 381: 86-89.
-
(1996)
Nature
, vol.381
, pp. 86-89
-
-
Maldonado, E.1
Shiekhattar, R.2
Sheldon, M.3
Cho, H.4
Drapkin, R.5
Rickert, P.6
Lees, E.7
-
75
-
-
62149105212
-
A role of DNA-PK for the metabolic gene regulation in response to insulin
-
Wong, R. H. F., Chang, I., Hudak, C. S. S., Hyun, S., Kwan, H.-Y. and Sul, H. S., A role of DNA-PK for the metabolic gene regulation in response to insulin. Cell 2009. 136: 1056-1072.
-
(2009)
Cell
, vol.136
, pp. 1056-1072
-
-
Wong, R.H.F.1
Chang, I.2
Hudak, C.S.S.3
Hyun, S.4
Kwan, H.-Y.5
Sul, H.S.6
-
76
-
-
79952283912
-
Estrogen receptor α-mediated transcription induces cell cycle-dependent DNA double-strand breaks
-
Williamson, L. M. and Lees-Miller, S. P., Estrogen receptor α-mediated transcription induces cell cycle-dependent DNA double-strand breaks. Carcinogenesis 2011. 32: 279-285.
-
(2011)
Carcinogenesis
, vol.32
, pp. 279-285
-
-
Williamson, L.M.1
Lees-Miller, S.P.2
-
77
-
-
84931577486
-
Activity-induced DNA breaks govern the expression of neuronal early-response genes
-
Madabhushi, R., Gao, F., Pfenning, A. R., Pan, L., Yamakawa, S., Seo, J., Rueda, R. et al., Activity-induced DNA breaks govern the expression of neuronal early-response genes. Cell. 2015. 161: 1592-1605.
-
(2015)
Cell
, vol.161
, pp. 1592-1605
-
-
Madabhushi, R.1
Gao, F.2
Pfenning, A.R.3
Pan, L.4
Yamakawa, S.5
Seo, J.6
Rueda, R.7
-
78
-
-
0035959633
-
DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates
-
Mondal, N. and Parvin, J. D., DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates. Nature 2001. 413: 435-438.
-
(2001)
Nature
, vol.413
, pp. 435-438
-
-
Mondal, N.1
Parvin, J.D.2
-
79
-
-
20744433548
-
Cooperative activation of transcription by autoimmune regulator AIRE and CBP
-
Pitkänen, J., Rebane, A., Rowell, J., Murumägi, A., Ströbel, P., Möll, K., Saare, M. et al., Cooperative activation of transcription by autoimmune regulator AIRE and CBP. Biochem. Biophys. Res. Commun. 2005. 333: 944-953.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.333
, pp. 944-953
-
-
Pitkänen, J.1
Rebane, A.2
Rowell, J.3
Murumägi, A.4
Ströbel, P.5
Möll, K.6
Saare, M.7
-
80
-
-
33847032959
-
SnapShot: histone-modifying enzymes
-
Kouzarides, T., SnapShot: histone-modifying enzymes. Cell. 2007. 128: 802.
-
(2007)
Cell
, vol.128
, pp. 802
-
-
Kouzarides, T.1
-
81
-
-
84931432951
-
The deacetylase Sirt1 is an essential regulator of AIRE-mediated induction of central immunological tolerance
-
Chuprin, A., Avin, A., Goldfarb, Y., Herzig, Y., Levi, B., Jacob, A., Sela, A. et al., The deacetylase Sirt1 is an essential regulator of AIRE-mediated induction of central immunological tolerance. Nat. Immunol. 2015. 16: 737-745.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 737-745
-
-
Chuprin, A.1
Avin, A.2
Goldfarb, Y.3
Herzig, Y.4
Levi, B.5
Jacob, A.6
Sela, A.7
-
82
-
-
84862884365
-
Autoimmune regulator is acetylated by transcription coactivator CBP/p300
-
Saare, M., Rebane, A., Rajashekar, B., Vilo, J. and Peterson, P., Autoimmune regulator is acetylated by transcription coactivator CBP/p300. Exp. Cell Res. 2012. 318: 1767-1778.
-
(2012)
Exp. Cell Res.
, vol.318
, pp. 1767-1778
-
-
Saare, M.1
Rebane, A.2
Rajashekar, B.3
Vilo, J.4
Peterson, P.5
-
83
-
-
77953693097
-
Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway
-
Huang, B., Yang, X.-D., Lamb, A. and Chen, L.-F., Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway. Cell. Signal. 2010. 22: 1282-1290.
-
(2010)
Cell. Signal.
, vol.22
, pp. 1282-1290
-
-
Huang, B.1
Yang, X.-D.2
Lamb, A.3
Chen, L.-F.4
-
84
-
-
73649111322
-
PIAS proteins: pleiotropic interactors associated with SUMO
-
Rytinki, M. M., Kaikkonen, S., Pehkonen, P., Jääskeläinen, T. and Palvimo, J. J., PIAS proteins: pleiotropic interactors associated with SUMO. Cell. Mol. Life Sci. 2009. 66: 3029-3041.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 3029-3041
-
-
Rytinki, M.M.1
Kaikkonen, S.2
Pehkonen, P.3
Jääskeläinen, T.4
Palvimo, J.J.5
-
85
-
-
39149143991
-
Functional interaction of AIRE with PIAS1 in transcriptional regulation
-
Ilmarinen, T., Kangas, H., Kytömaa, T., Eskelin, P., Saharinen, J., Seeler, J.-S., Tanhuanpää, K. et al., Functional interaction of AIRE with PIAS1 in transcriptional regulation. Mol. Immunol. 2008. 45: 1847-1862.
-
(2008)
Mol. Immunol.
, vol.45
, pp. 1847-1862
-
-
Ilmarinen, T.1
Kangas, H.2
Kytömaa, T.3
Eskelin, P.4
Saharinen, J.5
Seeler, J.-S.6
Tanhuanpää, K.7
-
86
-
-
84921446420
-
Homeodomain-interacting protein kinase 2, a novel autoimmune regulator interaction partner, modulates promiscuous gene expression in medullary thymic epithelial cells
-
Rattay, K., Claude, J., Rezavandy, E., Matt, S., Hofmann, T. G., Kyewski, B. and Derbinski, J., Homeodomain-interacting protein kinase 2, a novel autoimmune regulator interaction partner, modulates promiscuous gene expression in medullary thymic epithelial cells. J. Immunol. 2015. 194: 921-928.
-
(2015)
J. Immunol.
, vol.194
, pp. 921-928
-
-
Rattay, K.1
Claude, J.2
Rezavandy, E.3
Matt, S.4
Hofmann, T.G.5
Kyewski, B.6
Derbinski, J.7
-
87
-
-
33846913249
-
HIPK2: a versatile switchboard regulating the transcription machinery and cell death
-
Calzado, M. A., Renner, F., Roscic, A. and Schmitz, M. L., HIPK2: a versatile switchboard regulating the transcription machinery and cell death. Cell Cycle 2007. 6: 139-143.
-
(2007)
Cell Cycle
, vol.6
, pp. 139-143
-
-
Calzado, M.A.1
Renner, F.2
Roscic, A.3
Schmitz, M.L.4
-
88
-
-
84891598526
-
The PML-interacting protein DAXX: histone loading gets into the picture
-
Salomoni, P., The PML-interacting protein DAXX: histone loading gets into the picture. Front. Oncol. 2013. 3: 152.
-
(2013)
Front. Oncol.
, vol.3
, pp. 152
-
-
Salomoni, P.1
-
89
-
-
0032721540
-
PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1
-
Ishov, A. M., Sotnikov, A. G., Negorev, D., Vladimirova, O V., Neff, N., Kamitani, T., Yeh, E. T. et al., PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1. J. Cell Biol. 1999. 147: 221-234.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 221-234
-
-
Ishov, A.M.1
Sotnikov, A.G.2
Negorev, D.3
Vladimirova, O.V.4
Neff, N.5
Kamitani, T.6
Yeh, E.T.7
-
90
-
-
33846421621
-
Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death
-
Li, Q., Wang, X., Wu, X., Rui, Y., Liu, W., Wang, J., Wang, X. et al., Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death. Cancer Res. 2007. 67: 66-74.
-
(2007)
Cancer Res
, vol.67
, pp. 66-74
-
-
Li, Q.1
Wang, X.2
Wu, X.3
Rui, Y.4
Liu, W.5
Wang, J.6
Wang, X.7
-
91
-
-
56549103395
-
The cohesin complex and its roles in chromosome biology
-
Peters, J.-M., Tedeschi, A. and Schmitz, J., The cohesin complex and its roles in chromosome biology. Genes Dev. 2008. 22: 3089-3114.
-
(2008)
Genes Dev.
, vol.22
, pp. 3089-3114
-
-
Peters, J.-M.1
Tedeschi, A.2
Schmitz, J.3
-
92
-
-
60149110358
-
Pre-mRNA processing reaches back to transcription and ahead to translation
-
Moore, M. J. and Proudfoot, N. J., Pre-mRNA processing reaches back to transcription and ahead to translation. Cell 2009. 136: 688-700.
-
(2009)
Cell
, vol.136
, pp. 688-700
-
-
Moore, M.J.1
Proudfoot, N.J.2
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