-
1
-
-
0035798665
-
The autoimmune regulator (AIRE) is a DNA-binding protein
-
Kumar, P. G., M. Laloraya, C. Y. Wang, Q. G. Ruan, A. Davoodi-Semiromi, K. J. Kao, and J. X. She. 2001. The autoimmune regulator (AIRE) is a DNA-binding protein. J. Biol. Chem. 276: 41357-41364.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 41357-41364
-
-
Kumar, P.G.1
Laloraya, M.2
Wang, C.Y.3
Ruan, Q.G.4
Davoodi-Semiromi, A.5
Kao, K.J.6
She, J.X.7
-
2
-
-
1642500086
-
AIRE functions as an E3 ubiquitin ligase
-
Uchida, D., S. Hatakeyama, A. Matsushima, H. Han, S. Ishido, H. Hotta, J. Kudoh, N. Shimizu, V. Doucas, K. I. Nakayama, et al. 2004. AIRE functions as an E3 ubiquitin ligase. J. Exp. Med. 199: 167-172.
-
(2004)
J. Exp. Med
, vol.199
, pp. 167-172
-
-
Uchida, D.1
Hatakeyama, S.2
Matsushima, A.3
Han, H.4
Ishido, S.5
Hotta, H.6
Kudoh, J.7
Shimizu, N.8
Doucas, V.9
Nakayama, K.I.10
-
3
-
-
16944367194
-
Positional cloning of the APECED gene
-
Nagamine, K., P. Peterson, H. S. Scott, J. Kudoh, S. Minoshima, M. Heino, K. J. Krohn, M. D. Lalioti, P. E. Mullis, S. E. Antonarakis, et al. 1997. Positional cloning of the APECED gene. Nat. Genet. 17: 393-398.
-
(1997)
Nat. Genet
, vol.17
, pp. 393-398
-
-
Nagamine, K.1
Peterson, P.2
Scott, H.S.3
Kudoh, J.4
Minoshima, S.5
Heino, M.6
Krohn, K.J.7
Lalioti, M.D.8
Mullis, P.E.9
Antonarakis, S.E.10
-
4
-
-
0346599403
-
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
-
Finnish-German APECED Consortium
-
Finnish-German APECED Consortium. 1997. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat. Genet. 17: 399-403.
-
(1997)
Nat. Genet
, vol.17
, pp. 399-403
-
-
-
5
-
-
0028064998
-
An autosomal locus causing autoimmune disease: Autoimmune polyglandular disease type I assigned to chromosome 21
-
Aaltonen, J., P. Bjorses, L. Sandkuijl, J. Perheentupa, and L. Peltonen. 1994. An autosomal locus causing autoimmune disease: autoimmune polyglandular disease type I assigned to chromosome 21. Nat. Genet. 8: 83-87.
-
(1994)
Nat. Genet
, vol.8
, pp. 83-87
-
-
Aaltonen, J.1
Bjorses, P.2
Sandkuijl, L.3
Perheentupa, J.4
Peltonen, L.5
-
6
-
-
0031685004
-
Gene defect behind APECED: A new clue to autoimmunity
-
Bjorses, P., J. Aaltonen, N. Horelli-Kuitunen, M. L. Yaspo, and L. Peltonen. 1998. Gene defect behind APECED: a new clue to autoimmunity. Hum. Mol. Genet. 7: 1547-1553.
-
(1998)
Hum. Mol. Genet
, vol.7
, pp. 1547-1553
-
-
Bjorses, P.1
Aaltonen, J.2
Horelli-Kuitunen, N.3
Yaspo, M.L.4
Peltonen, L.5
-
7
-
-
0037084784
-
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
-
Ramsey, C., O. Winqvist, L. Puhakka, M. Halonen, A. Moro, O. Kampe, P. Eskelin, M. Pelto-Huikko, and L. Peltonen. 2002. Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum. Mol. Genet. 11: 397-409.
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 397-409
-
-
Ramsey, C.1
Winqvist, O.2
Puhakka, L.3
Halonen, M.4
Moro, A.5
Kampe, O.6
Eskelin, P.7
Pelto-Huikko, M.8
Peltonen, L.9
-
8
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson, M. S., E. S. Venanzi, L. Klein, Z. Chen, S. P. Berzins, S. J. Turley, H. von Boehmer, R. Bronson, A. Dierich, C. Benoist, and D. Mathis. 2002. Projection of an immunological self shadow within the thymus by the aire protein. Science 298: 1395-1401.
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
von Boehmer, H.7
Bronson, R.8
Dierich, A.9
Benoist, C.10
Mathis, D.11
-
9
-
-
13544262691
-
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice
-
Kuroda, N., T. Mitani, N. Takeda, N. Ishimaru, R. Arakaki, Y. Hayashi, Y. Bando, K. Izumi, T. Takahashi, T. Nomura, et al. 2005. Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J. Immunol. 174: 1862-1870.
-
(2005)
J. Immunol
, vol.174
, pp. 1862-1870
-
-
Kuroda, N.1
Mitani, T.2
Takeda, N.3
Ishimaru, N.4
Arakaki, R.5
Hayashi, Y.6
Bando, Y.7
Izumi, K.8
Takahashi, T.9
Nomura, T.10
-
10
-
-
0035171545
-
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
-
Derbinski, J., A. Schulte, B. Kyewski, and L. Klein. 2001. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol. 2: 1032-1039.
-
(2001)
Nat. Immunol
, vol.2
, pp. 1032-1039
-
-
Derbinski, J.1
Schulte, A.2
Kyewski, B.3
Klein, L.4
-
11
-
-
23844558032
-
The cellular mechanism of Aire control of T cell tolerance
-
Anderson, M. S., E. S. Venanzi, Z. Chen, S. P. Berzins, C. Benoist, and D. Mathis. 2005. The cellular mechanism of Aire control of T cell tolerance. Immunity 23: 227-239.
-
(2005)
Immunity
, vol.23
, pp. 227-239
-
-
Anderson, M.S.1
Venanzi, E.S.2
Chen, Z.3
Berzins, S.P.4
Benoist, C.5
Mathis, D.6
-
12
-
-
0030975776
-
An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis
-
Rodriguez, I., C. Ody, K. Araki, I. Garcia, and P. Vassalli. 1997. An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis. EMBO J. 16: 2262-2270.
-
(1997)
EMBO J
, vol.16
, pp. 2262-2270
-
-
Rodriguez, I.1
Ody, C.2
Araki, K.3
Garcia, I.4
Vassalli, P.5
-
13
-
-
0031033802
-
Morphological analysis of germ cell apoptosis during postnatal testis development in normal and Hsp 70-2 knockout mice
-
Mori, C., N. Nakamura, D. J. Dix, M. Fujioka, S. Nakagawa, K. Shiota, and E. M. Eddy. 1997. Morphological analysis of germ cell apoptosis during postnatal testis development in normal and Hsp 70-2 knockout mice. Dev. Dyn. 208: 125-136.
-
(1997)
Dev. Dyn
, vol.208
, pp. 125-136
-
-
Mori, C.1
Nakamura, N.2
Dix, D.J.3
Fujioka, M.4
Nakagawa, S.5
Shiota, K.6
Eddy, E.M.7
-
14
-
-
0031978777
-
Autonomous cell death of mouse male germ cells during fetal and postnatal period
-
Wang, R. A., P. K. Nakane, and T. Koji. 1998. Autonomous cell death of mouse male germ cells during fetal and postnatal period. Biol. Reprod. 58: 1250-1256.
-
(1998)
Biol. Reprod
, vol.58
, pp. 1250-1256
-
-
Wang, R.A.1
Nakane, P.K.2
Koji, T.3
-
15
-
-
0030003958
-
Inhibition of testicular germ cell apoptosis and differentiation in mice misexpressing Bcl-2 in spermatogonia
-
Furuchi, T., K. Masuko, Y. Nishimune, M. Obinata, and Y. Matsui. 1996. Inhibition of testicular germ cell apoptosis and differentiation in mice misexpressing Bcl-2 in spermatogonia. Development 122: 1703-1709.
-
(1996)
Development
, vol.122
, pp. 1703-1709
-
-
Furuchi, T.1
Masuko, K.2
Nishimune, Y.3
Obinata, M.4
Matsui, Y.5
-
16
-
-
0034064385
-
Germ cell suicide: New insights into apoptosis during spermatogenesis
-
Print, C. G., and K. L. Loveland. 2000. Germ cell suicide: new insights into apoptosis during spermatogenesis. BioEssays 22: 423-430.
-
(2000)
BioEssays
, vol.22
, pp. 423-430
-
-
Print, C.G.1
Loveland, K.L.2
-
17
-
-
0344284564
-
Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
-
Shimodaira, H., A. Yoshioka-Yamashita, R. D. Kolodner, and J. Y. Wang. 2003. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc. Natl. Acad. Sci. USA 100: 2420-2425.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2420-2425
-
-
Shimodaira, H.1
Yoshioka-Yamashita, A.2
Kolodner, R.D.3
Wang, J.Y.4
-
18
-
-
16344393332
-
Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements
-
Chen, J., and I. Sadowski. 2005. Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements. Proc. Natl. Acad. Sci. USA 102: 4813-4818.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4813-4818
-
-
Chen, J.1
Sadowski, I.2
-
19
-
-
0034282743
-
Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways
-
Zeng, M., L. Narayanan, X. S. Xu, T. A. Prolla, R. M. Liskay, and P. M. Glazer. 2000. Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways. Cancer Res. 60: 4889-4893.
-
(2000)
Cancer Res
, vol.60
, pp. 4889-4893
-
-
Zeng, M.1
Narayanan, L.2
Xu, X.S.3
Prolla, T.A.4
Liskay, R.M.5
Glazer, P.M.6
-
20
-
-
0029099989
-
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
-
Baker, S. M., C. E. Bronner, L. Zhang, A. W. Plug, M. Robatzek, G. Warren, E. A. Elliott, J. Yu, T. Ashley, N. Arnheim, et al. 1995. Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell 82: 309-319.
-
(1995)
Cell
, vol.82
, pp. 309-319
-
-
Baker, S.M.1
Bronner, C.E.2
Zhang, L.3
Plug, A.W.4
Robatzek, M.5
Warren, G.6
Elliott, E.A.7
Yu, J.8
Ashley, T.9
Arnheim, N.10
-
21
-
-
32244444497
-
Morphogenics as a tool for target discovery and drug development
-
Nicolaides, N. C., W. Ebel, B. Kline, Q. Chao, E. Routhier, P. M. Sass, and L. Grasso. 2005. Morphogenics as a tool for target discovery and drug development. Ann. NY Acad. Sci. 1059: 86-96.
-
(2005)
Ann. NY Acad. Sci
, vol.1059
, pp. 86-96
-
-
Nicolaides, N.C.1
Ebel, W.2
Kline, B.3
Chao, Q.4
Routhier, E.5
Sass, P.M.6
Grasso, L.7
-
22
-
-
0035147378
-
Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)
-
Halonen, M., M. Pelto-Huikko, P. Eskelin, L. Peltonen, I. Ulmanen, and M. Kolmer. 2001. Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED). J. Histochem. Cytochem. 49: 197-208.
-
(2001)
J. Histochem. Cytochem
, vol.49
, pp. 197-208
-
-
Halonen, M.1
Pelto-Huikko, M.2
Eskelin, P.3
Peltonen, L.4
Ulmanen, I.5
Kolmer, M.6
-
23
-
-
0036498116
-
Expression of AIRE gene in peripheral monocyte/ dendritic cell lineage
-
Kogawa, K., S. Nagafuchi, H. Katsuta, J. Kudoh, S. Tamiya, Y. Sakai, N. Shimizu, and M. Harada. 2002. Expression of AIRE gene in peripheral monocyte/ dendritic cell lineage. Immunol. Lett. 80: 195-198.
-
(2002)
Immunol. Lett
, vol.80
, pp. 195-198
-
-
Kogawa, K.1
Nagafuchi, S.2
Katsuta, H.3
Kudoh, J.4
Tamiya, S.5
Sakai, Y.6
Shimizu, N.7
Harada, M.8
-
24
-
-
0033590981
-
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla
-
Heino, M., P. Peterson, J. Kudoh, K. Nagamine, A. Lagerstedt, V. Ovod, A. Ranki, I. Rantala, M. Nieminen, J. Tuukkanen, et al. 1999. Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem. Biophys. Res. Commun. 257: 821-825.
-
(1999)
Biochem. Biophys. Res. Commun
, vol.257
, pp. 821-825
-
-
Heino, M.1
Peterson, P.2
Kudoh, J.3
Nagamine, K.4
Lagerstedt, A.5
Ovod, V.6
Ranki, A.7
Rantala, I.8
Nieminen, M.9
Tuukkanen, J.10
-
25
-
-
0033939699
-
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
-
Heino, M., P. Peterson, N. Sillanpaa, S. Guerin, L. Wu, G. Anderson, H. S. Scott, S. E. Antonarakis, J. Kudoh, N. Shimizu, et al. 2000. RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse. Eur. J. Immunol. 30: 1884-1893.
-
(2000)
Eur. J. Immunol
, vol.30
, pp. 1884-1893
-
-
Heino, M.1
Peterson, P.2
Sillanpaa, N.3
Guerin, S.4
Wu, L.5
Anderson, G.6
Scott, H.S.7
Antonarakis, S.E.8
Kudoh, J.9
Shimizu, N.10
-
26
-
-
33747091587
-
Expression profiling of autoimmune regulator AIRE mRNA in a comprehensive set of human normal and neoplastic tissues
-
Klamp, T., U. Sahin, B. Kyewski, J. Schwendemann, K. Dhaene, and O. Tureci. 2006. Expression profiling of autoimmune regulator AIRE mRNA in a comprehensive set of human normal and neoplastic tissues. Immunol. Lett. 106: 172-179.
-
(2006)
Immunol. Lett
, vol.106
, pp. 172-179
-
-
Klamp, T.1
Sahin, U.2
Kyewski, B.3
Schwendemann, J.4
Dhaene, K.5
Tureci, O.6
-
27
-
-
7244227646
-
Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
-
Liston, A., D. H. Gray, S. Lesage, A. L. Fletcher, J. Wilson, K. E. Webster, H. S. Scott, R. L. Boyd, L. Peltonen, and C. C. Goodnow. 2004. Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. J. Exp. Med. 200: 1015-1026.
-
(2004)
J. Exp. Med
, vol.200
, pp. 1015-1026
-
-
Liston, A.1
Gray, D.H.2
Lesage, S.3
Fletcher, A.L.4
Wilson, J.5
Webster, K.E.6
Scott, H.S.7
Boyd, R.L.8
Peltonen, L.9
Goodnow, C.C.10
-
28
-
-
0031910118
-
A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype
-
Nicolaides, N. C., S. J. Littman, P. Modrich, K. W. Kinzler, and B. Vogelstein. 1998. A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Mol. Cell. Biol. 18: 1635-1641.
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 1635-1641
-
-
Nicolaides, N.C.1
Littman, S.J.2
Modrich, P.3
Kinzler, K.W.4
Vogelstein, B.5
-
29
-
-
0035930660
-
Dnmt3L and the establishment of maternal genomic imprints
-
Bourc'his, D., G. L. Xu, C. S. Lin, B. Bollman, and T. H. Bestor. 2001. Dnmt3L and the establishment of maternal genomic imprints. Science 294: 2536-2539.
-
(2001)
Science
, vol.294
, pp. 2536-2539
-
-
Bourc'his, D.1
Xu, G.L.2
Lin, C.S.3
Bollman, B.4
Bestor, T.H.5
-
30
-
-
4544223707
-
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L
-
Bourc'his, D., and T. H. Bestor. 2004. Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature 431: 96-99.
-
(2004)
Nature
, vol.431
, pp. 96-99
-
-
Bourc'his, D.1
Bestor, T.H.2
-
31
-
-
33846551979
-
Sex-specific promoters regulate Dnmt3L expression in mouse germ cells
-
Shovlin, T. C., D. Bourc'his, S. La Salle, A. O'Doherty, J. M. Trasler, T. H. Bestor, and C. P. Walsh. 2007. Sex-specific promoters regulate Dnmt3L expression in mouse germ cells. Hum. Reprod. 22: 457-467.
-
(2007)
Hum. Reprod
, vol.22
, pp. 457-467
-
-
Shovlin, T.C.1
Bourc'his, D.2
La Salle, S.3
O'Doherty, A.4
Trasler, J.M.5
Bestor, T.H.6
Walsh, C.P.7
|