The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1842, Issue 2, 2014, Pages 326-337

  Perniola, Roberto ^a   Musco, Giovanna ^b  

^a VITO FAZZI HOSPITAL   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Autoimmune polyendocrinopathies; Post translational protein processing; Protein conformation; Self tolerance; Transcription factors

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; T LYMPHOCYTE RECEPTOR;

APOPTOSIS; BIOCHEMISTRY; BIOPHYSICS; CELLULAR DISTRIBUTION; DNA BINDING; GENETIC TRANSCRIPTION; HUMAN; LYMPHOID ORGAN; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHYLOGENY; PLANT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; T LYMPHOCYTE;

100-KDA SPECKLED PROTEIN; 110-KDA SPECKLED PROTEIN; 140-KDA SPECKLED PROTEIN; AA; AIRE; AMINO ACID(S); APECED; APS1; AUTOIMMUNE POLYENDOCRINOPATHIES; AUTOIMMUNE POLYENDOCRINOPATHY-CANDIDIASIS-ECTODERMAL DYSTROPHY; AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1; AUTOIMMUNE REGULATOR; CARD; CASPASE-RECRUITMENT DOMAIN; CBP; CHIP; CHROMATIN IMMUNOPRECIPITATION; CIITA; CLASS-II MAJOR HISTOCOMPATIBILITY COMPLEX; COIMMUNOPRECIPITATION; COIP; CREB-BINDING PROTEIN; DAXX; DEAF1; DEATH-ASSOCIATED PROTEIN 6; DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EMSA; GFP; GLUTATHIONE-S-TRANSFERASE; GREEN FLUORESCENT PROTEIN; GST; HEK293; HOMOGENEOUSLY-STAINING REGION; HSR; HUMAN-EMBRYONIC-KIDNEY EPITHELIAL-CELL LINE 293; ING2; INHIBITOR OF GROWTH 2; MASS SPECTROMETRY; MEDULLARY THYMIC EPITHELIAL CELL; MHCII; MHCII TRANSACTIVATOR; MM/PBSA; MOLECULAR MECHANICS/POISSON-BOLTZMANN SURFACE AREA; MS; MTEC; NB; NLS; NMR; NUCLEAR BODY; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR MAGNETIC RESONANCE; NUCLEAR PHOSPHOPROTEIN 41/75; NUCP41/75; P-TEFB; PGE; PHD; PIAS1; PK; PLANT HOMEODOMAIN; PML; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; POST-TRANSLATIONAL MODIFICATION; POST-TRANSLATIONAL PROTEIN PROCESSING; PROLINE-RICH REGION; PROMISCUOUS GENE EXPRESSION; PROMYELOCYTIC LEUKEMIA; PROTEIN CONFORMATION; PROTEIN INHIBITOR OF ACTIVATED STAT 1; PROTEIN KINASE; PRR; PTM; REALLY-INTERESTING NEW GENE; RING; RNA-POLII; RNA-POLYMERASE II; SAND; SELF-TOLERANCE; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; SP100; SP100, AIRE, NUCP41/75 AND DEAF1; SP110; SP140; STAT; TISSUE-SPECIFIC ANTIGEN; TRANSCRIPTION FACTORS; TSAG;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION FACTORS;

EID: 84891339888     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2013.11.020     Document Type: Review

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