-
1
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson, M.S., E.S. Venanzi, L. Klein, Z. Chen, S.P. Berzins, S.J. Turley, H. von Boehmer, R. Bronson, A. Dierich, C. Benoist, and D. Mathis. 2002. Projection of an immunological self shadow within the thymus by the aire protein. Science. 298:1395-1401. http://dx.doi.org/10.1126/science.1075958
-
(2002)
Science.
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
von Boehmer, H.7
Bronson, R.8
Dierich, A.9
Benoist, C.10
Mathis, D.11
-
2
-
-
34248598295
-
+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
-
+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. Nat. Immunol. 8:351-358. http://dx.doi.org/10.1038/ni1444
-
(2007)
Nat. Immunol.
, vol.8
, pp. 351-358
-
-
Aschenbrenner, K.1
D'Cruz, L.M.2
Vollmann, E.H.3
Hinterberger, M.4
Emmerich, J.5
Swee, L.K.6
Rolink, A.7
Klein, L.8
-
3
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli, E., Y. Carrier, W. Gao, T. Korn, T.B. Strom, M. Oukka, H.L. Weiner, and V.K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 441:235-238. http://dx.doi.org/10.1038/nature04753
-
(2006)
Nature.
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
4
-
-
9144228777
-
Continued maturation of thymic emigrants in the periphery
-
Boursalian, T.E., J. Golob, D.M. Soper, C.J. Cooper, and P.J. Fink. 2004. Continued maturation of thymic emigrants in the periphery. Nat. Immunol. 5:418-425. http://dx.doi.org/10.1038/ni1049
-
(2004)
Nat. Immunol.
, vol.5
, pp. 418-425
-
-
Boursalian, T.E.1
Golob, J.2
Soper, D.M.3
Cooper, C.J.4
Fink, P.J.5
-
5
-
-
0028952482
-
Expression of relB is required for the development of thymic medulla and dendritic cells
-
Burkly, L., C. Hession, L. Ogata, C. Reilly, L.A. Marconi, D. Olson, R. Tizard, R. Cate, and D. Lo. 1995. Expression of relB is required for the development of thymic medulla and dendritic cells. Nature. 373:531-536. http://dx.doi.org/10.1038/373531a0
-
(1995)
Nature.
, vol.373
, pp. 531-536
-
-
Burkly, L.1
Hession, C.2
Ogata, L.3
Reilly, C.4
Marconi, L.A.5
Olson, D.6
Tizard, R.7
Cate, R.8
Lo, D.9
-
6
-
-
33746334804
-
Kruppel-like factor 2 regulates thymocyte and T-cell migration
-
Carlson, C.M., B.T. Endrizzi, J. Wu, X. Ding, M.A. Weinreich, E.R. Walsh, M.A. Wani, J.B. Lingrel, K.A. Hogquist, and S.C. Jameson. 2006. Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature. 442:299-302. http://dx.doi.org/10.1038/nature04882
-
(2006)
Nature.
, vol.442
, pp. 299-302
-
-
Carlson, C.M.1
Endrizzi, B.T.2
Wu, J.3
Ding, X.4
Weinreich, M.A.5
Walsh, E.R.6
Wani, M.A.7
Lingrel, J.B.8
Hogquist, K.A.9
Jameson, S.C.10
-
7
-
-
57449117667
-
PlexinD1 glycoprotein controls migration of positively selected thymocytes into the medulla
-
Choi, Y.I., J.S. Duke-Cohan, W.B. Ahmed, M.A. Handley, F. Mann, J.A. Epstein, L.K. Clayton, and E.L. Reinherz. 2008. PlexinD1 glycoprotein controls migration of positively selected thymocytes into the medulla. Immunity. 29:888-898. http://dx.doi.org/10.1016/j.immuni.2008.10.008
-
(2008)
Immunity.
, vol.29
, pp. 888-898
-
-
Choi, Y.I.1
Duke-Cohan, J.S.2
Ahmed, W.B.3
Handley, M.A.4
Mann, F.5
Epstein, J.A.6
Clayton, L.K.7
Reinherz, E.L.8
-
8
-
-
79961133166
-
Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice
-
Gaspal, F.M., D. Withers, M. Saini, V. Bekiaris, F.M. McConnell, A. White, M. Khan, H. Yagita, L.S. Walker, G. Anderson, and P.J. Lane. 2011. Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice. J. Exp. Med. 208:1579-1584. http://dx.doi.org/10.1084/jem.20101484
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1579-1584
-
-
Gaspal, F.M.1
Withers, D.2
Saini, M.3
Bekiaris, V.4
McConnell, F.M.5
White, A.6
Khan, M.7
Yagita, H.8
Walker, L.S.9
Anderson, G.10
Lane, P.J.11
-
9
-
-
70449353483
-
T cells require Foxo1 to populate the peripheral lymphoid organs
-
Gubbels Bupp, M.R., B. Edwards, C. Guo, D. Wei, G. Chen, B. Wong, E. Masteller, and S.L. Peng. 2009. T cells require Foxo1 to populate the peripheral lymphoid organs. Eur. J. Immunol. 39:2991-2999. http://dx.doi.org/10.1002/eji.200939427
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2991-2999
-
-
Gubbels Bupp, M.R.1
Edwards, B.2
Guo, C.3
Wei, D.4
Chen, G.5
Wong, B.6
Masteller, E.7
Peng, S.L.8
-
10
-
-
58149384269
-
Back to the thymus: peripheral T cells come home
-
Hale, J.S., and P.J. Fink. 2009. Back to the thymus: peripheral T cells come home. Immunol. Cell Biol. 87:58-64. http://dx.doi.org/10.1038/icb.2008.87
-
(2009)
Immunol. Cell Biol.
, vol.87
, pp. 58-64
-
-
Hale, J.S.1
Fink, P.J.2
-
11
-
-
0033939699
-
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
-
Heino, M., P. Peterson, N. Sillanpää, S. Gu., and érin, L. Wu, G. Anderson, H.S. Scott, S.E. Antonarakis, J. Kudoh, N. Shimizu, et al. 2000. RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse. Eur. J. Immunol. 30:1884-1893. http://dx.doi.org/10.1002/1521-4141(200007)30:7<1884::AIDIMMU1884> 3.0.CO;2-P
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1884-1893
-
-
Heino, M.1
Peterson, P.2
Sillanpää, N.3
Guérin, S.4
Wu, L.5
Anderson, G.6
Scott, H.S.7
Antonarakis, S.E.8
Kudoh, J.9
Shimizu, N.10
-
12
-
-
77952568022
-
Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance
-
Hinterberger, M., M. Aichinger, O. Prazeres da Costa, D. Voehringer, R. Hoffmann, and L. Klein. 2010. Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance. Nat. Immunol. 11:512-519. http://dx.doi.org/10.1038/ni.1874
-
(2010)
Nat. Immunol.
, vol.11
, pp. 512-519
-
-
Hinterberger, M.1
Aichinger, M.2
da Costa, O.P.3
Voehringer, D.4
Hoffmann, R.5
Klein, L.6
-
13
-
-
82155170171
-
B7/CD28 in central tolerance: costimulation promotes maturation of regulatory T cell precursors and prevents their clonal deletion
-
Hinterberger, M., G. Wirnsberger, and L. Klein. 2011. B7/CD28 in central tolerance: costimulation promotes maturation of regulatory T cell precursors and prevents their clonal deletion. Front. Immunol. 2:30. http://dx.doi.org/10.3389/fimmu.2011.00030
-
(2011)
Front. Immunol.
, vol.2
, pp. 30
-
-
Hinterberger, M.1
Wirnsberger, G.2
Klein, L.3
-
14
-
-
32244432265
-
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance
-
Kurobe, H., C. Liu, T. Ueno, F. Saito, I. Ohigashi, N. Seach, R. Arakaki, Y. Hayashi, T. Kitagawa, M. Lipp, et al. 2006. CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. Immunity. 24:165-177. http://dx.doi.org/10.1016/j.immuni.2005.12.011
-
(2006)
Immunity.
, vol.24
, pp. 165-177
-
-
Kurobe, H.1
Liu, C.2
Ueno, T.3
Saito, F.4
Ohigashi, I.5
Seach, N.6
Arakaki, R.7
Hayashi, Y.8
Kitagawa, T.9
Lipp, M.10
-
15
-
-
36749066715
-
+CD8-medullary thymocytes during mouse ontogeny and its defect in Aire-/-mice
-
+CD8-medullary thymocytes during mouse ontogeny and its defect in Aire-/-mice. Proc. Natl. Acad. Sci. USA. 104:18175-18180. http://dx.doi.org/10.1073/pnas.0708884104
-
(2007)
Proc. Natl. Acad. Sci. USA.
, vol.104
, pp. 18175-18180
-
-
Li, J.1
Li, Y.2
Yao, J.Y.3
Jin, R.4
Zhu, M.Z.5
Qian, X.P.6
Zhang, J.7
Fu, Y.X.8
Wu, L.9
Zhang, Y.10
Chen, W.F.11
-
16
-
-
37849009964
-
A two-step process for thymic regulatory T cell development
-
Lio, C.W., and C.S. Hsieh. 2008. A two-step process for thymic regulatory T cell development. Immunity. 28:100-111. http://dx.doi.org/10.1016/j.immuni.2007.11.021
-
(2008)
Immunity.
, vol.28
, pp. 100-111
-
-
Lio, C.W.1
Hsieh, C.S.2
-
17
-
-
77953415548
-
CD28 facilitates the generation of Foxp3(-) cytokine responsive regulatory T cell precursors
-
Lio, C.W., L.F. Dodson, C.M. Deppong, C.S. Hsieh, and J.M. Green. 2010. CD28 facilitates the generation of Foxp3(-) cytokine responsive regulatory T cell precursors. J. Immunol. 184:6007-6013. http://dx.doi.org/10.4049/jimmunol.1000019
-
(2010)
J. Immunol.
, vol.184
, pp. 6007-6013
-
-
Lio, C.W.1
Dodson, L.F.2
Deppong, C.M.3
Hsieh, C.S.4
Green, J.M.5
-
19
-
-
1642580757
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
-
Matloubian, M., C.G. Lo, G. Cinamon, M.J. Lesneski, Y. Xu, V. Brinkmann, M.L. Allende, R.L. Proia, and J.G. Cyster. 2004. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature. 427:355-360. http://dx.doi.org/10.1038/nature02284
-
(2004)
Nature.
, vol.427
, pp. 355-360
-
-
Matloubian, M.1
Lo, C.G.2
Cinamon, G.3
Lesneski, M.J.4
Xu, Y.5
Brinkmann, V.6
Allende, M.L.7
Proia, R.L.8
Cyster, J.G.9
-
20
-
-
35748979722
-
Thymic emigration revisited
-
McCaughtry, T.M., M.S. Wilken, and K.A. Hogquist. 2007. Thymic emigration revisited. J. Exp. Med. 204:2513-2520. http://dx.doi.org/10.1084/jem.20070601
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2513-2520
-
-
McCaughtry, T.M.1
Wilken, M.S.2
Hogquist, K.A.3
-
21
-
-
58149376454
-
Dendritic cells in the thymus contribute to T-regulatory cell induction
-
Proietto, A.I., S. van Dommelen, P. Zhou, A. Rizzitelli, A. D'Amico, R.J. Steptoe, S.H. Naik, M.H. Lahoud, Y. Liu, P. Zheng, et al. 2008. Dendritic cells in the thymus contribute to T-regulatory cell induction. Proc. Natl. Acad. Sci. USA. 105:19869-19874. http://dx.doi.org/10.1073/pnas.0810268105
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 19869-19874
-
-
Proietto, A.I.1
van Dommelen, S.2
Zhou, P.3
Rizzitelli, A.4
D'Amico, A.5
Steptoe, R.J.6
Naik, S.H.7
Lahoud, M.H.8
Liu, Y.9
Zheng, P.10
-
22
-
-
84858795036
-
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium
-
Roberts, N.A., A.J. White, W.E. Jenkinson, G. Turchinovich, K. Nakamura, D.R. Withers, F.M. McConnell, G.E. Desanti, C. Benezech, S.M. Parnell, et al. 2012. Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium. Immunity. 36:427-437. http://dx.doi.org/10.1016/j.immuni.2012.01.016
-
(2012)
Immunity.
, vol.36
, pp. 427-437
-
-
Roberts, N.A.1
White, A.J.2
Jenkinson, W.E.3
Turchinovich, G.4
Nakamura, K.5
Withers, D.R.6
McConnell, F.M.7
Desanti, G.E.8
Benezech, C.9
Parnell, S.M.10
-
23
-
-
34250336454
-
RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
-
Rossi, S.W., M.Y. Kim, A. Leibbrandt, S.M. Parnell, W.E. Jenkinson, S.H. Glanville, F.M. McConnell, H.S. Scott, J.M. Penninger, E.J. Jenkinson, et al. 2007. RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J. Exp. Med. 204:1267-1272. http://dx.doi.org/10.1084/jem.20062497
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1267-1272
-
-
Rossi, S.W.1
Kim, M.Y.2
Leibbrandt, A.3
Parnell, S.M.4
Jenkinson, W.E.5
Glanville, S.H.6
McConnell, F.M.7
Scott, H.S.8
Penninger, J.M.9
Jenkinson, E.J.10
-
24
-
-
38949101205
-
+ regulatory T cells promiscuously accept thymic signals critical for their development
-
+ regulatory T cells promiscuously accept thymic signals critical for their development. Proc. Natl. Acad. Sci. USA. 105:973-978. http://dx.doi.org/10.1073/pnas.0709071105
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 973-978
-
-
Spence, P.J.1
Green, E.A.2
-
25
-
-
77952767221
-
Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development
-
Vang, K.B., J. Yang, A.J. Pagán, L.X. Li, J. Wang, J.M. Green, A.A. Beg, and M.A. Farrar. 2010. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. J. Immunol. 184:4074-4077. http://dx.doi.org/10.4049/jimmunol.0903933
-
(2010)
J. Immunol.
, vol.184
, pp. 4074-4077
-
-
Vang, K.B.1
Yang, J.2
Pagán, A.J.3
Li, L.X.4
Wang, J.5
Green, J.M.6
Beg, A.A.7
Farrar, M.A.8
-
26
-
-
0028817585
-
Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family
-
Weih, F., D. Carrasco, S.K. Durham, D.S. Barton, C.A. Rizzo, R.P. Ryseck, S.A. Lira, and R. Bravo. 1995. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family. Cell. 80:331-340. http://dx.doi.org/10.1016/0092-8674(95)90416-6
-
(1995)
Cell.
, vol.80
, pp. 331-340
-
-
Weih, F.1
Carrasco, D.2
Durham, S.K.3
Barton, D.S.4
Rizzo, C.A.5
Ryseck, R.P.6
Lira, S.A.7
Bravo, R.8
-
27
-
-
67649844269
-
Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control
-
Wirnsberger, G., F. Mair, and L. Klein. 2009. Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control. Proc. Natl. Acad. Sci. USA. 106:10278-10283. http://dx.doi.org/10.1073/pnas.0901877106
-
(2009)
Proc. Natl. Acad. Sci. USA.
, vol.106
, pp. 10278-10283
-
-
Wirnsberger, G.1
Mair, F.2
Klein, L.3
-
28
-
-
0001722505
-
RelB is essential for the development of myeloid-related CD8alpha-dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells
-
Wu, L., A. D'Amico, K.D. Winkel, M. Suter, D. Lo, and K. Shortman. 1998. RelB is essential for the development of myeloid-related CD8alpha-dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells. Immunity. 9:839-847. http://dx.doi.org/10.1016/S1074-7613(00)80649-4
-
(1998)
Immunity.
, vol.9
, pp. 839-847
-
-
Wu, L.1
D'Amico, A.2
Winkel, K.D.3
Suter, M.4
Lo, D.5
Shortman, K.6
-
29
-
-
0033549813
-
Continued RAG expression in late stages of B cell development and no apparent reinduction after immunization
-
Yu, W., H. Nagaoka, M. Jankovic, Z. Misulovin, H. Suh, A. Rolink, F. Melchers, E. Meffre, and M.C. Nussenzweig. 1999. Continued RAG expression in late stages of B cell development and no apparent reinduction after immunization. Nature. 400:682-687. http://dx.doi.org/ 10.1038/23287
-
(1999)
Nature.
, vol.400
, pp. 682-687
-
-
Yu, W.1
Nagaoka, H.2
Jankovic, M.3
Misulovin, Z.4
Suh, H.5
Rolink, A.6
Melchers, F.7
Meffre, E.8
Nussenzweig, M.C.9
|