Deletional tolerance mediated by extrathymic aire-expressing cells

Science

Volumn 321, Issue 5890, 2008, Pages 843-847

  Gardner, James M ^a   DeVoss, Jason J ^a   Friedman, Rachel S ^a   Wong, David J ^b   Tan, Ying X ^a   Zhou, Xuyu ^a   Johannes, Kellsey P ^a   Su, Maureen A ^a   Chang, Howard Y ^b   Krummel, Matthew F ^a   Anderson, Mark S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN;

ANTIGEN; CYTOLOGY; IMMUNITY; MATURATION;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CELL ADHESION; CELL MATURATION; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOFLUORESCENCE; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN PRESENTATION; AUTOANTIGENS; AUTOIMMUNITY; CELL PROLIFERATION; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GLUCOSE-6-PHOSPHATASE; LYMPH NODES; LYMPHOID TISSUE; MICE; MICE, TRANSGENIC; PROTEINS; SELF TOLERANCE; SPLEEN; STROMAL CELLS; T-LYMPHOCYTES; THYMUS GLAND; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 49449093723     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1159407     Document Type: Article

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24. We thank J. Bluestone, A. Abbas, N. Killeen, and J. Cyster for helpful discussion. J.G. is funded by the UCSF/NIH Medical Scientist Training Program and the American Diabetes Association, J.D. by the Giannini Foundation, R.F. by the Larry L. Hillblom Foundation, and D.W. by a Dermatology Foundation Research Career Development Award. M.S.A. is supported by the Pew Scholars Program, the Sandler Foundation, and the Burroughs Wellcome Fund. This work was supported in part by NIH (to M.S.A.). The authors have no competing financial interests.