Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 2, 2012, Pages 535-540

  Giraud, Matthieu ^a,d   Yoshid, Hideyuki ^a   Abramson, Jakub ^a,e   Rahl, Peter B ^b   Young, Richard A ^b,c   Mathis, Diane ^a   Benoist, Christophe ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d INSTITUT COCHIN   (France)

^e WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Autoimmunity; Thymus

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; ELONGATION FACTOR; KRUPPEL LIKE FACTOR 4; RNA POLYMERASE; TISSUE ANTIGEN;

ANIMAL CELL; ARTICLE; EPITHELIUM CELL; GENE EXPRESSION; HIGH THROUGHPUT SEQUENCING; IN VIVO STUDY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; TRANSCRIPTION REGULATION;

ANIMALS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA-DIRECTED RNA POLYMERASES; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MICE; MICE, INBRED C57BL; MICROARRAY ANALYSIS; SELF TOLERANCE; T-LYMPHOCYTES; THYMUS GLAND; TRANSCRIPTION FACTORS;

EID: 84855995571     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1119351109     Document Type: Article

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