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Volumn 8, Issue 1, 2016, Pages 4-31

Novel cancer antigens for personalized immunotherapies: Latest evidence and clinical potential

Author keywords

Antitumor antibody; Cancer vaccine; Cancer testis antigen; Immunotherapy; Oncofetal antigen; Tumor associated antigen

Indexed keywords

5T4 SUPERANTIGEN ANTIBODY FUSION PROTEIN; ACID PHOSPHATASE PROSTATE ISOENZYME; ANTINEOPLASTIC AGENT; ATEZOLIZUMAB; BMS 936559; CANCER VACCINE; CETUXIMAB; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DIOXYGENASE; DURVALUMAB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GAMMA UROGASTRONE; HYBRID PROTEIN; INDOLAMINE 2,3 DIOXYGENASE; MODIFIED VACCINIA VIRUS ANKARA 5T4 VACCINE; MONOCLONAL ANTIBODY; MUCIN 1; NECITUMUMAB; NIVOLUMAB; ONCOFETAL ANTIGEN; PANITUMUMAB; PROGRAMMED DEATH 1 RECEPTOR; SURVIVIN; TIM 3; TRASTUZUMAB; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2;

EID: 84951790085     PISSN: 17588340     EISSN: 17588359     Source Type: Journal    
DOI: 10.1177/1758834015615514     Document Type: Review
Times cited : (39)

References (276)
  • 1
    • 84899493381 scopus 로고    scopus 로고
    • SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed / refractory acute lymphocytic leukaemia
    • Advani A. McDonough S. Coutre S. Wood B. Radich J. Mims M. et al. (2014) SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed / refractory acute lymphocytic leukaemia. Br J Haematol 165: 504–509.
    • (2014) Br J Haematol , vol.165 , pp. 504-509
    • Advani, A.1    McDonough, S.2    Coutre, S.3    Wood, B.4    Radich, J.5    Mims, M.6
  • 2
    • 84880916857 scopus 로고    scopus 로고
    • The novel cancer-testis antigen A-kinase anchor protein 4 (AKAP4) is a potential target for immunotherapy of ovarian serous carcinoma
    • Agarwal S. Saini S. Parashar D. Verma A. Sinha A. Jagadish N. et al. (2013) The novel cancer-testis antigen A-kinase anchor protein 4 (AKAP4) is a potential target for immunotherapy of ovarian serous carcinoma. Oncoimmunology 2: e24270.
    • (2013) Oncoimmunology , vol.2 , pp. e24270
    • Agarwal, S.1    Saini, S.2    Parashar, D.3    Verma, A.4    Sinha, A.5    Jagadish, N.6
  • 3
    • 84922961118 scopus 로고    scopus 로고
    • Current status of antibody therapy in ALL
    • Ai J. Advani A. (2015) Current status of antibody therapy in ALL. Br J Haematol 168: 471–480.
    • (2015) Br J Haematol , vol.168 , pp. 471-480
    • Ai, J.1    Advani, A.2
  • 4
    • 84908131192 scopus 로고    scopus 로고
    • Novel cancer-testis antigen expression on glioma cell lines derived from high-grade glioma patients
    • Akiyama Y. Komiyama M. Miyata H. Yagoto M. Ashizawa T. Iizuka A. et al. (2014) Novel cancer-testis antigen expression on glioma cell lines derived from high-grade glioma patients. Oncol Rep 31: 1683–1690.
    • (2014) Oncol Rep , vol.31 , pp. 1683-1690
    • Akiyama, Y.1    Komiyama, M.2    Miyata, H.3    Yagoto, M.4    Ashizawa, T.5    Iizuka, A.6
  • 5
    • 0036498936 scopus 로고    scopus 로고
    • An anti-idiotype vaccine elicits a specific response to N-glycolyl sialic acid residues of glycoconjugates in melanoma patients
    • Alfonso M. Diaz A. Hernandez A. Perez A. Rodriguez E. Bitton R. et al. (2002) An anti-idiotype vaccine elicits a specific response to N-glycolyl sialic acid residues of glycoconjugates in melanoma patients. J Immunol 168: 2523–2529.
    • (2002) J Immunol , vol.168 , pp. 2523-2529
    • Alfonso, M.1    Diaz, A.2    Hernandez, A.3    Perez, A.4    Rodriguez, E.5    Bitton, R.6
  • 6
    • 84904386095 scopus 로고    scopus 로고
    • A randomized, multicenter, placebo-controlled clinical trial of racotumomab-alum vaccine as switch maintenance therapy in advanced non-small cell lung cancer patients
    • Alfonso S. Valdes-Zayas A. Santiesteban E. Flores Y. Areces F. Hernandez M. et al. (2014) A randomized, multicenter, placebo-controlled clinical trial of racotumomab-alum vaccine as switch maintenance therapy in advanced non-small cell lung cancer patients. Clin Cancer Res 20: 3660–3671.
    • (2014) Clin Cancer Res , vol.20 , pp. 3660-3671
    • Alfonso, S.1    Valdes-Zayas, A.2    Santiesteban, E.3    Flores, Y.4    Areces, F.5    Hernandez, M.6
  • 7
    • 58149186474 scopus 로고    scopus 로고
    • CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens
    • Almeida L. Sakabe N. de Oliveira A. Silva M. Mundstein A. Cohen T. et al. (2009) CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens. Nucleic Acids Res 37: D816–D819.
    • (2009) Nucleic Acids Res , vol.37 , pp. D816-D819
    • Almeida, L.1    Sakabe, N.2    de Oliveira, A.3    Silva, M.4    Mundstein, A.5    Cohen, T.6
  • 8
    • 78349284842 scopus 로고    scopus 로고
    • Vaccination of metastatic renal cancer patients with MVA-5T4: a randomized, double-blind, placebo-controlled phase III study
    • Amato R. Hawkins R. Kaufman H. Thompson J. Tomczak P. Szczylik C. et al. (2010) Vaccination of metastatic renal cancer patients with MVA-5T4: a randomized, double-blind, placebo-controlled phase III study. Clin Cancer Res 16: 5539–5547.
    • (2010) Clin Cancer Res , vol.16 , pp. 5539-5547
    • Amato, R.1    Hawkins, R.2    Kaufman, H.3    Thompson, J.4    Tomczak, P.5    Szczylik, C.6
  • 9
    • 84922391334 scopus 로고    scopus 로고
    • TIM-3: an emerging target in the cancer immunotherapy landscape
    • Anderson A. (2014) TIM-3: an emerging target in the cancer immunotherapy landscape. Cancer Immunol Res 2: 393–398.
    • (2014) Cancer Immunol Res , vol.2 , pp. 393-398
    • Anderson, A.1
  • 10
    • 0037112047 scopus 로고    scopus 로고
    • Projection of an immunological self shadow within the thymus by the Aire protein
    • Anderson M. Venanzi E. Klein L. Chen Z. Berzins S. Turley S. et al. (2002) Projection of an immunological self shadow within the thymus by the Aire protein. Science 298: 1395–1401.
    • (2002) Science , vol.298 , pp. 1395-1401
    • Anderson, M.1    Venanzi, E.2    Klein, L.3    Chen, Z.4    Berzins, S.5    Turley, S.6
  • 11
    • 84993813859 scopus 로고    scopus 로고
    • Novel agents for the treatment of childhood acute leukemia
    • Annesley C. Brown P. (2015) Novel agents for the treatment of childhood acute leukemia. Ther Adv Hematol 6: 61–79.
    • (2015) Ther Adv Hematol , vol.6 , pp. 61-79
    • Annesley, C.1    Brown, P.2
  • 12
    • 0028649555 scopus 로고
    • Cellular mucins: targets for immunotherapy
    • Apostolopoulos V. McKenzie I. (1994) Cellular mucins: targets for immunotherapy. Crit Rev Immunol 14: 293–309.
    • (1994) Crit Rev Immunol , vol.14 , pp. 293-309
    • Apostolopoulos, V.1    McKenzie, I.2
  • 13
    • 34548452131 scopus 로고    scopus 로고
    • Clinical safety of a viral vector based prostate cancer vaccine strategy
    • Arlen P. Skarupa L. Pazdur M. Seetharam M. Tsang K. Grosenbach D. et al. (2007) Clinical safety of a viral vector based prostate cancer vaccine strategy. J Urol 178: 1515–1520.
    • (2007) J Urol , vol.178 , pp. 1515-1520
    • Arlen, P.1    Skarupa, L.2    Pazdur, M.3    Seetharam, M.4    Tsang, K.5    Grosenbach, D.6
  • 14
    • 84890096527 scopus 로고    scopus 로고
    • Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international phase II trial
    • Armand P. Nagler A. Weller E. Devine S. Avigan D. Chen Y. et al. (2013) Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international phase II trial. J Clin Oncol 31: 4199–4206.
    • (2013) J Clin Oncol , vol.31 , pp. 4199-4206
    • Armand, P.1    Nagler, A.2    Weller, E.3    Devine, S.4    Avigan, D.5    Chen, Y.6
  • 15
    • 84907613231 scopus 로고    scopus 로고
    • Phase 2, multicenter, safety and efficacy study of pidilizumab in patients with metastatic melanoma
    • abstract 9001.
    • Atkins M. Kudchadkar R. Sznol M. McDermott D. Lotem M. Schachter J. et al. (2014) Phase 2, multicenter, safety and efficacy study of pidilizumab in patients with metastatic melanoma. J Clin Oncol 32(Suppl. 5): abstract 9001.
    • (2014) J Clin Oncol , vol.32
    • Atkins, M.1    Kudchadkar, R.2    Sznol, M.3    McDermott, D.4    Lotem, M.5    Schachter, J.6
  • 16
    • 84867437406 scopus 로고    scopus 로고
    • Immunotherapy against HPV16/18 generates potent TH 1 and cytotoxic cellular immune responses
    • Bagarazzi M. Yan J. Morrow M. Shen X. Parker R. Lee J. et al. (2012) Immunotherapy against HPV16/18 generates potent TH 1 and cytotoxic cellular immune responses. Sci Transl Med 4: 155ra138.
    • (2012) Sci Transl Med , vol.4 , pp. 155ra138
    • Bagarazzi, M.1    Yan, J.2    Morrow, M.3    Shen, X.4    Parker, R.5    Lee, J.6
  • 17
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
    • Bang Y. van Cutsem E. Feyereislova A. Chung H. Shen L. Sawaki A. et al. (2010) Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 376: 687–697.
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.1    van Cutsem, E.2    Feyereislova, A.3    Chung, H.4    Shen, L.5    Sawaki, A.6
  • 18
    • 84890442740 scopus 로고    scopus 로고
    • Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis
    • Beauchemin N. Arabzadeh A. (2013) Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis. Cancer Metastasis Rev 32: 643–671.
    • (2013) Cancer Metastasis Rev , vol.32 , pp. 643-671
    • Beauchemin, N.1    Arabzadeh, A.2
  • 19
    • 84871005306 scopus 로고    scopus 로고
    • Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma
    • Becker J. Andersen M. Hofmeister-Muller V. Wobser M. Frey L. Sandig C. et al. (2012) Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma. Cancer Immunol Immunother 61: 2091–2103.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 2091-2103
    • Becker, J.1    Andersen, M.2    Hofmeister-Muller, V.3    Wobser, M.4    Frey, L.5    Sandig, C.6
  • 21
    • 59949091448 scopus 로고    scopus 로고
    • Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
    • Bokemeyer C. Bondarenko I. Makhson A. Hartmann J. Aparicio J. de Braud F. et al. (2009) Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 27: 663–671.
    • (2009) J Clin Oncol , vol.27 , pp. 663-671
    • Bokemeyer, C.1    Bondarenko, I.2    Makhson, A.3    Hartmann, J.4    Aparicio, J.5    de Braud, F.6
  • 22
    • 84862026304 scopus 로고    scopus 로고
    • Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials
    • Bokemeyer C. van Cutsem E. Rougier P. Ciardiello F. Heeger S. Schlichting M. et al. (2012) Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials. Eur J Cancer 48: 1466–1475.
    • (2012) Eur J Cancer , vol.48 , pp. 1466-1475
    • Bokemeyer, C.1    van Cutsem, E.2    Rougier, P.3    Ciardiello, F.4    Heeger, S.5    Schlichting, M.6
  • 23
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Bonner J. Harari P. Giralt J. Azarnia N. Shin D. Cohen R. et al. (2006) Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354: 567–578.
    • (2006) N Engl J Med , vol.354 , pp. 567-578
    • Bonner, J.1    Harari, P.2    Giralt, J.3    Azarnia, N.4    Shin, D.5    Cohen, R.6
  • 24
    • 84951279998 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity activity of a novel anti-PD-L1 antibody avelumab (MSB0010718C) on human tumor cells
    • Boyerinas B. Jochems C. Fantini M. Heery C. Gulley J. Tsang K. et al. (2015) Antibody-dependent cellular cytotoxicity activity of a novel anti-PD-L1 antibody avelumab (MSB0010718C) on human tumor cells. Cancer Immunol Res 3: 1148–1157.
    • (2015) Cancer Immunol Res , vol.3 , pp. 1148-1157
    • Boyerinas, B.1    Jochems, C.2    Fantini, M.3    Heery, C.4    Gulley, J.5    Tsang, K.6
  • 25
    • 84936791837 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
    • Brahmer J. Reckamp K. Baas P. Crino L. Eberhardt W. Poddubskaya E. et al. (2015) Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med 373: 123–135.
    • (2015) N Engl J Med , vol.373 , pp. 123-135
    • Brahmer, J.1    Reckamp, K.2    Baas, P.3    Crino, L.4    Eberhardt, W.5    Poddubskaya, E.6
  • 26
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer J. Tykodi S. Chow L. Hwu W. Topalian S. Hwu P. et al. (2012) Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 366: 2455–2465.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.1    Tykodi, S.2    Chow, L.3    Hwu, W.4    Topalian, S.5    Hwu, P.6
  • 27
    • 4344682030 scopus 로고    scopus 로고
    • MUC1: a multifunctional cell surface component of reproductive tissue epithelia
    • Brayman M. Thathiah A. Carson D. (2004) MUC1: a multifunctional cell surface component of reproductive tissue epithelia. Reprod Biol Endocrinol 2: 4.
    • (2004) Reprod Biol Endocrinol , vol.2 , pp. 4
    • Brayman, M.1    Thathiah, A.2    Carson, D.3
  • 28
    • 77955487541 scopus 로고    scopus 로고
    • First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP 321 (LAG-3Ig) enhances immune responses and antitumor activity
    • Brignone C. Gutierrez M. Mefti F. Brain E. Jarcau R. Cvitkovic F. et al. (2010) First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP 321 (LAG-3Ig) enhances immune responses and antitumor activity. J Transl Med 8: 71.
    • (2010) J Transl Med , vol.8 , pp. 71
    • Brignone, C.1    Gutierrez, M.2    Mefti, F.3    Brain, E.4    Jarcau, R.5    Cvitkovic, F.6
  • 29
    • 79551485967 scopus 로고    scopus 로고
    • Regression of high-grade cervical intraepithelial neoplasia with TG 4001 targeted immunotherapy
    • Brun J. Dalstein V. Leveque J. Mathevet P. Raulic P. Baldauf J. et al. (2011) Regression of high-grade cervical intraepithelial neoplasia with TG 4001 targeted immunotherapy. Am J Obstet Gynecol 204: 169.e1–169.e8.
    • (2011) Am J Obstet Gynecol , vol.204 , pp. 169.e1-169.e8
    • Brun, J.1    Dalstein, V.2    Leveque, J.3    Mathevet, P.4    Raulic, P.5    Baldauf, J.6
  • 30
    • 84891373760 scopus 로고    scopus 로고
    • Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial
    • Butts C. Socinski M. Mitchell P. Thatcher N. Havel L. Krzakowski M. et al. (2014) Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial. Lancet Oncol 15: 59–68.
    • (2014) Lancet Oncol , vol.15 , pp. 59-68
    • Butts, C.1    Socinski, M.2    Mitchell, P.3    Thatcher, N.4    Havel, L.5    Krzakowski, M.6
  • 31
    • 84928585927 scopus 로고    scopus 로고
    • Immunological response induced by abagovomab as a maintenance therapy in patients with epithelial ovarian cancer: relationship with survival - a substudy of the MIMOSA trial
    • Buzzonetti A. Fossati M. Catzola V. Scambia G. Fattorossi A. Battaglia A. (2014) Immunological response induced by abagovomab as a maintenance therapy in patients with epithelial ovarian cancer: relationship with survival - a substudy of the MIMOSA trial. Cancer Immunol Immunother 63: 1037–1045.
    • (2014) Cancer Immunol Immunother , vol.63 , pp. 1037-1045
    • Buzzonetti, A.1    Fossati, M.2    Catzola, V.3    Scambia, G.4    Fattorossi, A.5    Battaglia, A.6
  • 33
    • 84884703526 scopus 로고    scopus 로고
    • Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial
    • Calabro L. Morra A. Fonsatti E. Cutaia O. Amato G. Giannarelli D. et al. (2013) Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial. Lancet Oncol 14: 1104–1111.
    • (2013) Lancet Oncol , vol.14 , pp. 1104-1111
    • Calabro, L.1    Morra, A.2    Fonsatti, E.3    Cutaia, O.4    Amato, G.5    Giannarelli, D.6
  • 34
    • 84902547851 scopus 로고    scopus 로고
    • Alternative activation of human plasmacytoid DCs in vitro and in melanoma lesions: involvement of LAG-3
    • Camisaschi C. de Filippo A. Beretta V. Vergani B. Villa A. Vergani E. et al. (2014) Alternative activation of human plasmacytoid DCs in vitro and in melanoma lesions: involvement of LAG-3. J Invest Dermatol 134: 1893–1902.
    • (2014) J Invest Dermatol , vol.134 , pp. 1893-1902
    • Camisaschi, C.1    de Filippo, A.2    Beretta, V.3    Vergani, B.4    Villa, A.5    Vergani, E.6
  • 35
    • 84929148767 scopus 로고    scopus 로고
    • PD-L1 inhibition with MPDL3280A for solid tumors
    • Cha E. Wallin J. Kowanetz M. (2015) PD-L1 inhibition with MPDL3280A for solid tumors. Semin Oncol 42: 484–487.
    • (2015) Semin Oncol , vol.42 , pp. 484-487
    • Cha, E.1    Wallin, J.2    Kowanetz, M.3
  • 36
    • 84891153613 scopus 로고    scopus 로고
    • Expression of the cancer-testis antigen BORIS correlates with prostate cancer
    • Cheema Z. Hari-Gupta Y. Kita G. Farrar D. Seddon I. Corr J. et al. (2014) Expression of the cancer-testis antigen BORIS correlates with prostate cancer. Prostate 74: 164–176.
    • (2014) Prostate , vol.74 , pp. 164-176
    • Cheema, Z.1    Hari-Gupta, Y.2    Kita, G.3    Farrar, D.4    Seddon, I.5    Corr, J.6
  • 37
    • 84914695668 scopus 로고    scopus 로고
    • SPAG9 expression is increased in human prostate cancer and promotes cell motility, invasion and angiogenesis in vitro
    • Chen F. Lu Z. Deng J. Han X. Bai J. Liu Q. et al. (2014) SPAG9 expression is increased in human prostate cancer and promotes cell motility, invasion and angiogenesis in vitro. Oncol Rep 32: 2533–2540.
    • (2014) Oncol Rep , vol.32 , pp. 2533-2540
    • Chen, F.1    Lu, Z.2    Deng, J.3    Han, X.4    Bai, J.5    Liu, Q.6
  • 38
    • 84922242690 scopus 로고    scopus 로고
    • NY-ESO-1 specific antibody and cellular responses in melanoma patients primed with NY-ESO-1 protein in ISCOMATRIX and boosted with recombinant NY-ESO-1 fowlpox virus
    • Chen J. Dawoodji A. Tarlton A. Gnjatic S. Tajar A. Karydis I. et al. (2015) NY-ESO-1 specific antibody and cellular responses in melanoma patients primed with NY-ESO-1 protein in ISCOMATRIX and boosted with recombinant NY-ESO-1 fowlpox virus. Int J Cancer 136: E590–E601.
    • (2015) Int J Cancer , vol.136 , pp. E590-E601
    • Chen, J.1    Dawoodji, A.2    Tarlton, A.3    Gnjatic, S.4    Tajar, A.5    Karydis, I.6
  • 39
    • 84929156508 scopus 로고    scopus 로고
    • Brentuximab vedotin for relapsed or refractory Hodgkin's lymphoma
    • Chen R. Chen B. (2015) Brentuximab vedotin for relapsed or refractory Hodgkin's lymphoma. Drug Des Devel Ther 9: 1729–1733.
    • (2015) Drug Des Devel Ther , vol.9 , pp. 1729-1733
    • Chen, R.1    Chen, B.2
  • 40
    • 12644276375 scopus 로고    scopus 로고
    • A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening
    • Chen Y. Scanlan M. Sahin U. Tureci O. Gure A. Tsang S. et al. (1997) A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc Natl Acad Sci U S A 94: 1914–1918.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1914-1918
    • Chen, Y.1    Scanlan, M.2    Sahin, U.3    Tureci, O.4    Gure, A.5    Tsang, S.6
  • 41
    • 84872252849 scopus 로고    scopus 로고
    • CIMAvax EGF vaccine for stage IIIb / IV non-small cell lung carcinoma
    • Cheng J. Kananathan R. (2012) CIMAvax EGF vaccine for stage IIIb / IV non-small cell lung carcinoma. Hum Vaccin Immunother 8: 1799–1801.
    • (2012) Hum Vaccin Immunother , vol.8 , pp. 1799-1801
    • Cheng, J.1    Kananathan, R.2
  • 42
    • 84951764096 scopus 로고    scopus 로고
    • Tim-3 and Tim-4 as the potential targets for antitumor therapy
    • Cheng L. Ruan Z. (2015) Tim-3 and Tim-4 as the potential targets for antitumor therapy. Hum Vaccin Immunother 11: 2458–2462.
    • (2015) Hum Vaccin Immunother , vol.11 , pp. 2458-2462
    • Cheng, L.1    Ruan, Z.2
  • 43
    • 84964241130 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors for epidermal growth factor receptor gene mutation-positive non-small cell lung cancers: an update for recent advances in therapeutics
    • DOI: 10.1177/1078155215577810
    • Chung C. (2015) Tyrosine kinase inhibitors for epidermal growth factor receptor gene mutation-positive non-small cell lung cancers: an update for recent advances in therapeutics. J Oncol Pharm Pract. DOI: 10.1177/1078155215577810.
    • (2015) J Oncol Pharm Pract
    • Chung, C.1
  • 44
    • 84901007308 scopus 로고    scopus 로고
    • Wilms’ tumor gene 1 immunotherapy in pelvic gynecological malignancies
    • Coosemans A. Vergote I. van Gool S. (2014) Wilms’ tumor gene 1 immunotherapy in pelvic gynecological malignancies. Expert Rev Clin Immunol 10: 705–711.
    • (2014) Expert Rev Clin Immunol , vol.10 , pp. 705-711
    • Coosemans, A.1    Vergote, I.2    van Gool, S.3
  • 45
    • 84890933630 scopus 로고    scopus 로고
    • Update on immune checkpoint inhibitors in lung cancer
    • Creelan B. (2014) Update on immune checkpoint inhibitors in lung cancer. Cancer Control 21: 80–89.
    • (2014) Cancer Control , vol.21 , pp. 80-89
    • Creelan, B.1
  • 46
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D. Humblet Y. Siena S. Khayat D. Bleiberg H. Santoro A. et al. (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351: 337–345.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3    Khayat, D.4    Bleiberg, H.5    Santoro, A.6
  • 47
    • 84884710173 scopus 로고    scopus 로고
    • Developing an effective breast cancer vaccine: challenges to achieving sterile immunity versus resetting equilibrium
    • Curigliano G. Criscitiello C. Esposito A. Fumagalli L. Gelao L. Locatelli M. et al. (2013) Developing an effective breast cancer vaccine: challenges to achieving sterile immunity versus resetting equilibrium. Breast 22(Suppl. 2): S96–S99.
    • (2013) Breast , vol.22 , pp. S96-S99
    • Curigliano, G.1    Criscitiello, C.2    Esposito, A.3    Fumagalli, L.4    Gelao, L.5    Locatelli, M.6
  • 48
  • 49
    • 84904903954 scopus 로고    scopus 로고
    • Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small cell lung cancer (START): a randomized, double-blind, phase III trial
    • de Gregorio M. Soe L. Wolf M. (2014) Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small cell lung cancer (START): a randomized, double-blind, phase III trial. J Thorac Dis 6: 571–573.
    • (2014) J Thorac Dis , vol.6 , pp. 571-573
    • de Gregorio, M.1    Soe, L.2    Wolf, M.3
  • 50
    • 84875366067 scopus 로고    scopus 로고
    • L-BLP25 vaccine plus letrozole for breast cancer: Is translation possible?
    • de Gregorio M. Wurz G. Gutierrez A. Wolf M. (2012) L-BLP25 vaccine plus letrozole for breast cancer: Is translation possible? OncoImmunology 1: 1422–1424.
    • (2012) OncoImmunology , vol.1 , pp. 1422-1424
    • de Gregorio, M.1    Wurz, G.2    Gutierrez, A.3    Wolf, M.4
  • 51
    • 22344449972 scopus 로고    scopus 로고
    • Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
    • Derbinski J. Gabler J. Brors B. Tierling S. Jonnakuty S. Hergenhahn M. et al. (2005) Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med 202: 33–45.
    • (2005) J Exp Med , vol.202 , pp. 33-45
    • Derbinski, J.1    Gabler, J.2    Brors, B.3    Tierling, S.4    Jonnakuty, S.5    Hergenhahn, M.6
  • 52
    • 84926616368 scopus 로고    scopus 로고
    • Review of the results of WT 1 peptide vaccination strategies for myelodysplastic syndromes and acute myeloid leukemia from nine different studies
    • Di Stasi A. Jimenez A. Minagawa K. Al-Obaidi M. Rezvani K. (2015) Review of the results of WT 1 peptide vaccination strategies for myelodysplastic syndromes and acute myeloid leukemia from nine different studies. Front Immunol 6: 36.
    • (2015) Front Immunol , vol.6 , pp. 36
    • Di Stasi, A.1    Jimenez, A.2    Minagawa, K.3    Al-Obaidi, M.4    Rezvani, K.5
  • 53
    • 0038577172 scopus 로고    scopus 로고
    • Immune responses in breast cancer patients immunized with an anti-idiotype antibody mimicking NeuGc-containing gangliosides
    • Diaz A. Alfonso M. Alonso R. Saurez G. Troche M. Catala M. et al. (2003) Immune responses in breast cancer patients immunized with an anti-idiotype antibody mimicking NeuGc-containing gangliosides. Clin Immunol 107: 80–89.
    • (2003) Clin Immunol , vol.107 , pp. 80-89
    • Diaz, A.1    Alfonso, M.2    Alonso, R.3    Saurez, G.4    Troche, M.5    Catala, M.6
  • 54
    • 84928956390 scopus 로고    scopus 로고
    • Cancer vaccines: can they improve survival?
    • Dillman R. (2015) Cancer vaccines: can they improve survival? Cancer Biother Radiopharm 30: 147–151.
    • (2015) Cancer Biother Radiopharm , vol.30 , pp. 147-151
    • Dillman, R.1
  • 55
    • 30544449854 scopus 로고    scopus 로고
    • A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer
    • Di Paola R. Plante M. Kaufman H. Petrylak D. Israeli R. Lattime E. et al. (2006) A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer. J Transl Med 4: 1.
    • (2006) J Transl Med , vol.4 , pp. 1
    • Di Paola, R.1    Plante, M.2    Kaufman, H.3    Petrylak, D.4    Israeli, R.5    Lattime, E.6
  • 56
    • 78149250536 scopus 로고    scopus 로고
    • Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX 4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study
    • Douillard J. Siena S. Cassidy J. Tabernero J. Burkes R. Barugel M. et al. (2010) Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX 4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 28: 4697–4705.
    • (2010) J Clin Oncol , vol.28 , pp. 4697-4705
    • Douillard, J.1    Siena, S.2    Cassidy, J.3    Tabernero, J.4    Burkes, R.5    Barugel, M.6
  • 57
    • 84899423143 scopus 로고    scopus 로고
    • Naptumomab estafenatox: targeted immunotherapy with a novel immunotoxin
    • Eisen T. Hedlund G. Forsberg G. Hawkins R. (2014) Naptumomab estafenatox: targeted immunotherapy with a novel immunotoxin. Curr Oncol Rep 16: 370.
    • (2014) Curr Oncol Rep , vol.16 , pp. 370
    • Eisen, T.1    Hedlund, G.2    Forsberg, G.3    Hawkins, R.4
  • 58
    • 84924255334 scopus 로고    scopus 로고
    • Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2 / 3 study of naptumomab estafenatox plus IFN-alpha versus IFN-alpha
    • Elkord E. Burt D. Sundstedt A. Nordle O. Hedlund G. Hawkins R. (2015) Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2 / 3 study of naptumomab estafenatox plus IFN-alpha versus IFN-alpha. Oncotarget 6: 4428–4439.
    • (2015) Oncotarget , vol.6 , pp. 4428-4439
    • Elkord, E.1    Burt, D.2    Sundstedt, A.3    Nordle, O.4    Hedlund, G.5    Hawkins, R.6
  • 59
    • 84951782867 scopus 로고    scopus 로고
    • Inhibition of PD-L1 by MPDL3280A leads to clinical activity in patients with metastatic triple-negative breast cancer (TNBC) (Abstract 2859)
    • Annual Meeting of the American Association for Cancer Research Philadelphia, PA
    • Emens L. Braiteh F. Cassier P. Delord J. Eder J. Fasso M. et al. (2015) Inhibition of PD-L1 by MPDL3280A leads to clinical activity in patients with metastatic triple-negative breast cancer (TNBC) (Abstract 2859). In: Annual Meeting of the American Association for Cancer Research, Philadelphia, PA, 18–22 April.
    • (2015)
    • Emens, L.1    Braiteh, F.2    Cassier, P.3    Delord, J.4    Eder, J.5    Fasso, M.6
  • 61
    • 77952300540 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival
    • Escudier B. Bellmunt J. Negrier S. Bajetta E. Melichar B. Bracarda S. et al. (2010) Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J Clin Oncol 28: 2144–2150.
    • (2010) J Clin Oncol , vol.28 , pp. 2144-2150
    • Escudier, B.1    Bellmunt, J.2    Negrier, S.3    Bajetta, E.4    Melichar, B.5    Bracarda, S.6
  • 62
    • 37349080670 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial
    • Escudier B. Pluzanska A. Koralewski P. Ravaud A. Bracarda S. Szczylik C. et al. (2007) Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 370: 2103–2111.
    • (2007) Lancet , vol.370 , pp. 2103-2111
    • Escudier, B.1    Pluzanska, A.2    Koralewski, P.3    Ravaud, A.4    Bracarda, S.5    Szczylik, C.6
  • 64
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • Ferrara N. Hillan K. Gerber H. Novotny W. (2004) Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 3: 391–400.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 391-400
    • Ferrara, N.1    Hillan, K.2    Gerber, H.3    Novotny, W.4
  • 65
    • 84965157146 scopus 로고
    • Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin
    • Foley E. (1953) Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin. Cancer Res 13: 835–837.
    • (1953) Cancer Res , vol.13 , pp. 835-837
    • Foley, E.1
  • 66
    • 84894266990 scopus 로고    scopus 로고
    • PD-1 and TIM-3 regulate the expansion of tumor antigen-specific CD8+ T cells induced by melanoma vaccines
    • Fourcade J. Sun Z. Pagliano O. Chauvin J. Sander C. Janjic B. et al. (2014) PD-1 and TIM-3 regulate the expansion of tumor antigen-specific CD8+ T cells induced by melanoma vaccines. Cancer Res 74: 1045–1055.
    • (2014) Cancer Res , vol.74 , pp. 1045-1055
    • Fourcade, J.1    Sun, Z.2    Pagliano, O.3    Chauvin, J.4    Sander, C.5    Janjic, B.6
  • 67
    • 70350461699 scopus 로고    scopus 로고
    • Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
    • Friedman H. Prados M. Wen P. Mikkelsen T. Schiff D. Abrey L. et al. (2009) Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 27: 4733–4740.
    • (2009) J Clin Oncol , vol.27 , pp. 4733-4740
    • Friedman, H.1    Prados, M.2    Wen, P.3    Mikkelsen, T.4    Schiff, D.5    Abrey, L.6
  • 68
    • 84892852372 scopus 로고    scopus 로고
    • Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial
    • Fuchs C. Tomasek J. Yong C. Dumitru F. Passalacqua R. Goswami C. et al. (2014) Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial. Lancet 383: 31–39.
    • (2014) Lancet , vol.383 , pp. 31-39
    • Fuchs, C.1    Tomasek, J.2    Yong, C.3    Dumitru, F.4    Passalacqua, R.5    Goswami, C.6
  • 70
    • 84857159981 scopus 로고    scopus 로고
    • TIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progression
    • Gao X. Zhu Y. Li G. Huang H. Zhang G. Wang F. et al. (2012) TIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progression. PloS ONE 7: e30676.
    • (2012) PloS ONE , vol.7 , pp. e30676
    • Gao, X.1    Zhu, Y.2    Li, G.3    Huang, H.4    Zhang, G.5    Wang, F.6
  • 71
    • 33947357850 scopus 로고    scopus 로고
    • Sperm-associated antigen 9, a novel cancer testis antigen, is a potential target for immunotherapy in epithelial ovarian cancer
    • Garg M. Chaurasiya D. Rana R. Jagadish N. Kanojia D. Dudha N. et al. (2007) Sperm-associated antigen 9, a novel cancer testis antigen, is a potential target for immunotherapy in epithelial ovarian cancer. Clin Cancer Res 13: 1421–1428.
    • (2007) Clin Cancer Res , vol.13 , pp. 1421-1428
    • Garg, M.1    Chaurasiya, D.2    Rana, R.3    Jagadish, N.4    Kanojia, D.5    Dudha, N.6
  • 72
    • 84906903314 scopus 로고    scopus 로고
    • Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial
    • Garon E. Ciuleanu T. Arrieta O. Prabhash K. Syrigos K. Goksel T. et al. (2014) Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial. Lancet 384: 665–673.
    • (2014) Lancet , vol.384 , pp. 665-673
    • Garon, E.1    Ciuleanu, T.2    Arrieta, O.3    Prabhash, K.4    Syrigos, K.5    Goksel, T.6
  • 74
    • 84925222392 scopus 로고    scopus 로고
    • Expression of cancer testis antigens CT 10 (MAGE-C2) and GAGE in gastrointestinal stromal tumors
    • Ghadban T. Perez D. Vashist Y. Bockhorn M. Koenig A. El Gammal A. et al. (2014) Expression of cancer testis antigens CT 10 (MAGE-C2) and GAGE in gastrointestinal stromal tumors. Eur J Surg Oncol 40: 1307–1312.
    • (2014) Eur J Surg Oncol , vol.40 , pp. 1307-1312
    • Ghadban, T.1    Perez, D.2    Vashist, Y.3    Bockhorn, M.4    Koenig, A.5    El Gammal, A.6
  • 75
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200
    • Giantonio B. Catalano P. Meropol N. O'Dwyer P. Mitchell E. Alberts S. et al. (2007) Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25: 1539–1544.
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.1    Catalano, P.2    Meropol, N.3    O'Dwyer, P.4    Mitchell, E.5    Alberts, S.6
  • 77
    • 33847041123 scopus 로고    scopus 로고
    • Therapeutic vaccination with epidermal growth factor (EGF) in advanced lung cancer: analysis of pooled data from three clinical trials
    • Gonzalez G. Crombet T. Neninger E. Viada C. Lage A. (2007) Therapeutic vaccination with epidermal growth factor (EGF) in advanced lung cancer: analysis of pooled data from three clinical trials. Hum Vaccin 3: 8–13.
    • (2007) Hum Vaccin , vol.3 , pp. 8-13
    • Gonzalez, G.1    Crombet, T.2    Neninger, E.3    Viada, C.4    Lage, A.5
  • 78
    • 0942288397 scopus 로고    scopus 로고
    • Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters
    • Gotter J. Brors B. Hergenhahn M. Kyewski B. (2004) Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J Exp Med 199: 155–166.
    • (2004) J Exp Med , vol.199 , pp. 155-166
    • Gotter, J.1    Brors, B.2    Hergenhahn, M.3    Kyewski, B.4
  • 79
    • 84929361061 scopus 로고    scopus 로고
    • Humoral immune response against nontargeted tumor antigens after treatment with sipuleucel-T and its association with improved clinical outcome
    • GuhaThakurta D. Sheikh N. Fan L. Kandadi H. Meagher T. Hall S. et al. (2015) Humoral immune response against nontargeted tumor antigens after treatment with sipuleucel-T and its association with improved clinical outcome. Clin Cancer Res 21: 3619–3630.
    • (2015) Clin Cancer Res , vol.21 , pp. 3619-3630
    • GuhaThakurta, D.1    Sheikh, N.2    Fan, L.3    Kandadi, H.4    Meagher, T.5    Hall, S.6
  • 80
    • 77950473925 scopus 로고    scopus 로고
    • Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer
    • Gulley J. Arlen P. Madan R. Tsang K. Pazdur M. Skarupa L. et al. (2010) Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer. Cancer Immunol Immunother 59: 663–674.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 663-674
    • Gulley, J.1    Arlen, P.2    Madan, R.3    Tsang, K.4    Pazdur, M.5    Skarupa, L.6
  • 81
    • 84944751040 scopus 로고    scopus 로고
    • Avelumab (MSB0010718C), an anti-PD-L1 antibody, in advanced NSCLC patients: A phase Ib, open-label expansion trial in patients progressing after platinum-based chemotherapy
    • abstract 8034.
    • Gulley J. Spigel D. Kelly K. Chandler J. Rajan A. Hassan R. et al. (2015) Avelumab (MSB0010718C), an anti-PD-L1 antibody, in advanced NSCLC patients: A phase Ib, open-label expansion trial in patients progressing after platinum-based chemotherapy. J Clin Oncol 33(Suppl.): abstract 8034.
    • (2015) J Clin Oncol , vol.33
    • Gulley, J.1    Spigel, D.2    Kelly, K.3    Chandler, J.4    Rajan, A.5    Hassan, R.6
  • 82
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
    • Hamid O. Robert C. Daud A. Hodi F. Hwu W. Kefford R. et al. (2013) Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 369: 134–144.
    • (2013) N Engl J Med , vol.369 , pp. 134-144
    • Hamid, O.1    Robert, C.2    Daud, A.3    Hodi, F.4    Hwu, W.5    Kefford, R.6
  • 83
    • 84883462585 scopus 로고    scopus 로고
    • Vaccination of castration-resistant prostate cancer patients with TroVax (MVA-5T4) in combination with docetaxel: a randomized phase II trial
    • Harrop R. Chu F. Gabrail N. Srinivas S. Blount D. Ferrari A. (2013) Vaccination of castration-resistant prostate cancer patients with TroVax (MVA-5T4) in combination with docetaxel: a randomized phase II trial. Cancer Immunol Immunother 62: 1511–1520.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 1511-1520
    • Harrop, R.1    Chu, F.2    Gabrail, N.3    Srinivas, S.4    Blount, D.5    Ferrari, A.6
  • 84
    • 78149282337 scopus 로고    scopus 로고
    • Cross-trial analysis of immunologic and clinical data resulting from phase I and II trials of MVA-5T4 (TroVax) in colorectal, renal, and prostate cancer patients
    • Harrop R. Shingler W. Kelleher M. de Belin J. Treasure P. (2010) Cross-trial analysis of immunologic and clinical data resulting from phase I and II trials of MVA-5T4 (TroVax) in colorectal, renal, and prostate cancer patients. J Immunother 33: 999–1005.
    • (2010) J Immunother , vol.33 , pp. 999-1005
    • Harrop, R.1    Shingler, W.2    Kelleher, M.3    de Belin, J.4    Treasure, P.5
  • 85
    • 84951752223 scopus 로고    scopus 로고
    • MEDI9447: Enhancing anti-tumor immunity by targeting CD73 in the tumor microenvironment
    • abstract 285.
    • Hay C. Sult E. Huang Q. Hammond S. Mulgrew K. McGlinchey K. et al. (2015) MEDI9447: Enhancing anti-tumor immunity by targeting CD73 in the tumor microenvironment. Cancer Res 75(Suppl. 15): abstract 285.
    • (2015) Cancer Res , vol.75
    • Hay, C.1    Sult, E.2    Huang, Q.3    Hammond, S.4    Mulgrew, K.5    McGlinchey, K.6
  • 87
    • 84965092640 scopus 로고    scopus 로고
    • Docetaxel alone or in combination with a therapeutic cancer vaccine (PANVAC) in patients with metastatic breast cancer: A randomized clinical trial
    • DOI: 10.1001/jamaoncol.2015.2736
    • Heery C. Ibrahim N. Arlen P. Mohebtash M. Murray J. Koenig K. et al. (2015) Docetaxel alone or in combination with a therapeutic cancer vaccine (PANVAC) in patients with metastatic breast cancer: A randomized clinical trial. JAMA Oncol. DOI: 10.1001/jamaoncol.2015.2736.
    • (2015) JAMA Oncol
    • Heery, C.1    Ibrahim, N.2    Arlen, P.3    Mohebtash, M.4    Murray, J.5    Koenig, K.6
  • 88
    • 84920956735 scopus 로고    scopus 로고
    • Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
    • Herbst R. Soria J. Kowanetz M. Fine G. Hamid O. Gordon M. et al. (2014) Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 515: 563–567.
    • (2014) Nature , vol.515 , pp. 563-567
    • Herbst, R.1    Soria, J.2    Kowanetz, M.3    Fine, G.4    Hamid, O.5    Gordon, M.6
  • 90
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi F. O'Day S. McDermott D. Weber R. Sosman J. Haanen J. et al. (2010) Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363: 711–723.
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.1    O'Day, S.2    McDermott, D.3    Weber, R.4    Sosman, J.5    Haanen, J.6
  • 91
    • 84901041371 scopus 로고    scopus 로고
    • Blinatumomab, a bi-specific anti-CD19/CD3 BiTE((R)) antibody for the treatment of acute lymphoblastic leukemia: perspectives and current pediatric applications
    • Hoffman L. Gore L. (2014) Blinatumomab, a bi-specific anti-CD19/CD3 BiTE((R)) antibody for the treatment of acute lymphoblastic leukemia: perspectives and current pediatric applications. Front Oncol 4: 63.
    • (2014) Front Oncol , vol.4 , pp. 63
    • Hoffman, L.1    Gore, L.2
  • 94
    • 84944714731 scopus 로고    scopus 로고
    • Clinical activity, safety and predictive biomarkers of the engineered antibody MPDL3280A (anti-PD-L1) in non-small cell lung cancer (NSCLC): update from a phase Ia study
    • abstract 8029.
    • Horn L. Spigel D. Gettinger S. Antonia S. Gordon M. Herbst R. et al. (2015) Clinical activity, safety and predictive biomarkers of the engineered antibody MPDL3280A (anti-PD-L1) in non-small cell lung cancer (NSCLC): update from a phase Ia study. J Clin Oncol 33(Suppl.): abstract 8029.
    • (2015) J Clin Oncol , vol.33
    • Horn, L.1    Spigel, D.2    Gettinger, S.3    Antonia, S.4    Gordon, M.5    Herbst, R.6
  • 96
    • 45549099784 scopus 로고    scopus 로고
    • Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
    • Hunder N. Wallen H. Cao J. Hendricks D. Reilly J. Rodmyre R. et al. (2008) Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. N Engl J Med 358: 2698–2703.
    • (2008) N Engl J Med , vol.358 , pp. 2698-2703
    • Hunder, N.1    Wallen, H.2    Cao, J.3    Hendricks, D.4    Reilly, J.5    Rodmyre, R.6
  • 97
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H. Fehrenbacher L. Novotny W. Cartwright T. Hainsworth J. Heim W. et al. (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350: 2335–2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3    Cartwright, T.4    Hainsworth, J.5    Heim, W.6
  • 98
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: the complexity of targeted inhibitors
    • Hynes N. Lane H. (2005) ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 5: 341–354.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.1    Lane, H.2
  • 99
    • 84893057242 scopus 로고    scopus 로고
    • Survival advantage in patients with metastatic breast cancer receiving endocrine therapy plus sialyl Tn-KLH vaccine: post hoc analysis of a large randomized trial
    • Ibrahim N. Murray J. Zhou D. Mittendorf E. Sample D. Tautchin M. et al. (2013) Survival advantage in patients with metastatic breast cancer receiving endocrine therapy plus sialyl Tn-KLH vaccine: post hoc analysis of a large randomized trial. J Cancer 4: 577–584.
    • (2013) J Cancer , vol.4 , pp. 577-584
    • Ibrahim, N.1    Murray, J.2    Zhou, D.3    Mittendorf, E.4    Sample, D.5    Tautchin, M.6
  • 100
    • 84929208764 scopus 로고    scopus 로고
    • PD-L1 blockade for cancer treatment: MEDI4736
    • Ibrahim R. Stewart R. Shalabi A. (2015) PD-L1 blockade for cancer treatment: MEDI4736. Semin Oncol 42: 474–483.
    • (2015) Semin Oncol , vol.42 , pp. 474-483
    • Ibrahim, R.1    Stewart, R.2    Shalabi, A.3
  • 102
    • 84891629936 scopus 로고    scopus 로고
    • Phase I clinical trial of vaccination with LY6K-derived peptide in patients with advanced gastric cancer
    • Ishikawa H. Imano M. Shiraishi O. Yasuda A. Peng Y. Shinkai M. et al. (2014) Phase I clinical trial of vaccination with LY6K-derived peptide in patients with advanced gastric cancer. Gastric Cancer 17: 173–180.
    • (2014) Gastric Cancer , vol.17 , pp. 173-180
    • Ishikawa, H.1    Imano, M.2    Shiraishi, O.3    Yasuda, A.4    Peng, Y.5    Shinkai, M.6
  • 103
    • 84919845152 scopus 로고    scopus 로고
    • The targeting of indoleamine 2,3 dioxygenase -mediated immune escape in cancer
    • Iversen T. Andersen M. Svane I. (2015) The targeting of indoleamine 2,3 dioxygenase -mediated immune escape in cancer. Basic Clin Pharmacol Toxicol 116: 19–24.
    • (2015) Basic Clin Pharmacol Toxicol , vol.116 , pp. 19-24
    • Iversen, T.1    Andersen, M.2    Svane, I.3
  • 104
    • 84892157282 scopus 로고    scopus 로고
    • Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase
    • Iversen T. Engell-Noerregaard L. Ellebaek E. Andersen R. Larsen S. Bjoern J. et al. (2014) Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase. Clin Cancer Res 20: 221–232.
    • (2014) Clin Cancer Res , vol.20 , pp. 221-232
    • Iversen, T.1    Engell-Noerregaard, L.2    Ellebaek, E.3    Andersen, R.4    Larsen, S.5    Bjoern, J.6
  • 105
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Iwai Y. Ishida M. Tanaka Y. Okazaki T. Honjo T. Minato N. (2002) Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A 99: 12293–12297.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 106
    • 84923180670 scopus 로고    scopus 로고
    • Research progress of indoleamine 2,3-dioxygenase inhibitors
    • Jiang T. Sun Y. Yin Z. Feng S. Sun L. Li Z. (2015) Research progress of indoleamine 2,3-dioxygenase inhibitors. Future Med Chem 7: 185–201.
    • (2015) Future Med Chem , vol.7 , pp. 185-201
    • Jiang, T.1    Sun, Y.2    Yin, Z.3    Feng, S.4    Sun, L.5    Li, Z.6
  • 107
    • 84977111467 scopus 로고    scopus 로고
    • Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma
    • Jing W. Gershan J. Weber J. Tlomak D. McOlash L. Sabatos-Peyton C. et al. (2015) Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma. J Immunother Cancer 3: 2.
    • (2015) J Immunother Cancer , vol.3 , pp. 2
    • Jing, W.1    Gershan, J.2    Weber, J.3    Tlomak, D.4    McOlash, L.5    Sabatos-Peyton, C.6
  • 109
    • 0035876940 scopus 로고    scopus 로고
    • Immunohistochemical analysis of NY-ESO-1 antigen expression in normal and malignant human tissues
    • Jungbluth A. Chen Y. Stockert E. Busam K. Kolb D. Iversen K. et al. (2001) Immunohistochemical analysis of NY-ESO-1 antigen expression in normal and malignant human tissues. Int J Cancer 92: 856–860.
    • (2001) Int J Cancer , vol.92 , pp. 856-860
    • Jungbluth, A.1    Chen, Y.2    Stockert, E.3    Busam, K.4    Kolb, D.5    Iversen, K.6
  • 110
    • 79952773140 scopus 로고    scopus 로고
    • Sperm-associated antigen 9 is a novel biomarker for colorectal cancer and is involved in tumor growth and tumorigenicity
    • Kanojia D. Garg M. Gupta S. Gupta A. Suri A. (2011) Sperm-associated antigen 9 is a novel biomarker for colorectal cancer and is involved in tumor growth and tumorigenicity. Am J Pathol 178: 1009–1020.
    • (2011) Am J Pathol , vol.178 , pp. 1009-1020
    • Kanojia, D.1    Garg, M.2    Gupta, S.3    Gupta, A.4    Suri, A.5
  • 111
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff P. Higano C. Shore N. Berger E. Small E. Penson D. et al. (2010 a) Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 363: 411–422.
    • (2010) N Engl J Med , vol.363 , pp. 411-422
    • Kantoff, P.1    Higano, C.2    Shore, N.3    Berger, E.4    Small, E.5    Penson, D.6
  • 112
    • 77949895922 scopus 로고    scopus 로고
    • Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer
    • Kantoff P. Schuetz T. Blumenstein B. Glode L. Bilhartz D. Wyand M. et al. (2010 b) Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol 28: 1099–1105.
    • (2010) J Clin Oncol , vol.28 , pp. 1099-1105
    • Kantoff, P.1    Schuetz, T.2    Blumenstein, B.3    Glode, L.4    Bilhartz, D.5    Wyand, M.6
  • 113
    • 84962040767 scopus 로고    scopus 로고
    • Assessing the effects of concurrent versus sequential cisplatin / radiotherapy on immune status in lung tumor-bearing C57BL/6 mice
    • Kao C. Wurz G. Lin Y. Vang D. Griffey S. Wolf M. et al. (2015) Assessing the effects of concurrent versus sequential cisplatin / radiotherapy on immune status in lung tumor-bearing C57BL/6 mice. Cancer Immunol Res 3: 741–750.
    • (2015) Cancer Immunol Res , vol.3 , pp. 741-750
    • Kao, C.1    Wurz, G.2    Lin, Y.3    Vang, D.4    Griffey, S.5    Wolf, M.6
  • 114
    • 84904901172 scopus 로고    scopus 로고
    • Antitumor effects of cisplatin combined with tecemotide immunotherapy in a human MUC 1 transgenic lung cancer mouse model
    • Kao C. Wurz G. Monjazeb A. Vang D. Cadman T. Griffey S. et al. (2014) Antitumor effects of cisplatin combined with tecemotide immunotherapy in a human MUC 1 transgenic lung cancer mouse model. Cancer Immunol Res 2: 581–589.
    • (2014) Cancer Immunol Res , vol.2 , pp. 581-589
    • Kao, C.1    Wurz, G.2    Monjazeb, A.3    Vang, D.4    Cadman, T.5    Griffey, S.6
  • 115
    • 0032560475 scopus 로고    scopus 로고
    • Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
    • Kaplan D. Shankaran V. Dighe A. Stockert E. Aguet M. Old L. et al. (1998) Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci U S A 95: 7556–7561.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7556-7561
    • Kaplan, D.1    Shankaran, V.2    Dighe, A.3    Stockert, E.4    Aguet, M.5    Old, L.6
  • 116
    • 84951765776 scopus 로고    scopus 로고
    • A phase II, open-label, multicenter trial to investigate the clinical activity and safety of avelumab (MSB0010718C) in patients with metastatic Merkel cell carcinoma
    • abstract TPS9086.
    • Kaufman H. Hamid O. D'Angelo S. Yuan G. Chin K. Bhatia S. et al. (2015) A phase II, open-label, multicenter trial to investigate the clinical activity and safety of avelumab (MSB0010718C) in patients with metastatic Merkel cell carcinoma. J Clin Oncol 33(Suppl.): abstract TPS9086.
    • (2015) J Clin Oncol , vol.33
    • Kaufman, H.1    Hamid, O.2    D'Angelo, S.3    Yuan, G.4    Chin, K.5    Bhatia, S.6
  • 117
    • 84926283904 scopus 로고    scopus 로고
    • High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy
    • Kawai T. Enomoto Y. Morikawa T. Matsushita H. Kume H. Fukayama M. et al. (2014) High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy. Mol Clin Oncol 2: 38–42.
    • (2014) Mol Clin Oncol , vol.2 , pp. 38-42
    • Kawai, T.1    Enomoto, Y.2    Morikawa, T.3    Matsushita, H.4    Kume, H.5    Fukayama, M.6
  • 118
    • 84951764509 scopus 로고    scopus 로고
    • Avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with metastatic or locally advanced solid tumors: assessment of safety and tolerability in a phase I., open-label expansion study
    • abstract 3044.
    • Kelly K. Patel M. Infante J. Iannotti N. Nikolinakos P. Leach J. et al. (2015) Avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with metastatic or locally advanced solid tumors: assessment of safety and tolerability in a phase I, open-label expansion study. J Clin Oncol 33(Suppl.): abstract 3044.
    • (2015) J Clin Oncol , vol.33
    • Kelly, K.1    Patel, M.2    Infante, J.3    Iannotti, N.4    Nikolinakos, P.5    Leach, J.6
  • 120
    • 84870931422 scopus 로고    scopus 로고
    • MUC1 immunotherapy is here to stay
    • Kimura T. Finn O. (2013) MUC1 immunotherapy is here to stay. Expert Opin Biol Ther 13: 35–49.
    • (2013) Expert Opin Biol Ther , vol.13 , pp. 35-49
    • Kimura, T.1    Finn, O.2
  • 122
    • 78651120598 scopus 로고
    • Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host
    • Klein G. Sjogren H. Klein E. Hellstrom K. (1960) Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host. Cancer Res 20: 1561–1572.
    • (1960) Cancer Res , vol.20 , pp. 1561-1572
    • Klein, G.1    Sjogren, H.2    Klein, E.3    Hellstrom, K.4
  • 123
    • 84925496069 scopus 로고    scopus 로고
    • Low-dose cyclophosphamide enhances antigen-specific CD4(+) T cell responses to NY-ESO-1/ISCOMATRIX vaccine in patients with advanced melanoma
    • Klein O. Davis I. McArthur G. Chen L. Haydon A. Parente P. et al. (2015) Low-dose cyclophosphamide enhances antigen-specific CD4(+) T cell responses to NY-ESO-1/ISCOMATRIX vaccine in patients with advanced melanoma. Cancer Immunol Immunother 64: 507–518.
    • (2015) Cancer Immunol Immunother , vol.64 , pp. 507-518
    • Klein, O.1    Davis, I.2    McArthur, G.3    Chen, L.4    Haydon, A.5    Parente, P.6
  • 125
    • 84894030202 scopus 로고    scopus 로고
    • Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies
    • Kohrt H. Thielens A. Marabelle A. Sagiv-Barfi I. Sola C. Chanuc F. et al. (2014) Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies. Blood 123: 678–686.
    • (2014) Blood , vol.123 , pp. 678-686
    • Kohrt, H.1    Thielens, A.2    Marabelle, A.3    Sagiv-Barfi, I.4    Sola, C.5    Chanuc, F.6
  • 126
    • 84880730418 scopus 로고    scopus 로고
    • Selection of immunostimulant AS 15 for active immunization with MAGE-A3 protein: results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma
    • Kruit W. Suciu S. Dreno B. Mortier L. Robert C. Chiarion-Sileni V. et al. (2013) Selection of immunostimulant AS 15 for active immunization with MAGE-A3 protein: results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma. J Clin Oncol 31: 2413–2420.
    • (2013) J Clin Oncol , vol.31 , pp. 2413-2420
    • Kruit, W.1    Suciu, S.2    Dreno, B.3    Mortier, L.4    Robert, C.5    Chiarion-Sileni, V.6
  • 127
    • 79960146645 scopus 로고    scopus 로고
    • Rational drug design: a GAGE derived peptide kills tumor cells
    • Kular R. Yehiely F. Deiss L. (2010) Rational drug design: a GAGE derived peptide kills tumor cells. Cancer Biol Ther 9: 825–831.
    • (2010) Cancer Biol Ther , vol.9 , pp. 825-831
    • Kular, R.1    Yehiely, F.2    Deiss, L.3
  • 129
    • 84897429090 scopus 로고    scopus 로고
    • VISTA Regulates the development of protective antitumor immunity
    • Le Mercier I. Chen W. Lines J. Day M. Li J. Sergent P. et al. (2014) VISTA Regulates the development of protective antitumor immunity. Cancer Res 74: 1933–1944.
    • (2014) Cancer Res , vol.74 , pp. 1933-1944
    • Le Mercier, I.1    Chen, W.2    Lines, J.3    Day, M.4    Li, J.5    Sergent, P.6
  • 130
    • 84907009512 scopus 로고    scopus 로고
    • Expression of the brother of the regulator of imprinted sites gene in the sputum of patients with lung cancer
    • Lee H. Kim J. Cho S. Ko T. Kim H. Park S. et al. (2014) Expression of the brother of the regulator of imprinted sites gene in the sputum of patients with lung cancer. Korean J Thorac Cardiovasc Surg 47: 378–383.
    • (2014) Korean J Thorac Cardiovasc Surg , vol.47 , pp. 378-383
    • Lee, H.1    Kim, J.2    Cho, S.3    Ko, T.4    Kim, H.5    Park, S.6
  • 131
    • 84939221583 scopus 로고    scopus 로고
    • A new addition to the PD-1 checkpoint inhibitors for non-small cell lung cancer-the anti-PDL1 antibody-MEDI4736
    • Lee S. Chow L. (2014) A new addition to the PD-1 checkpoint inhibitors for non-small cell lung cancer-the anti-PDL1 antibody-MEDI4736. Transl Lung Cancer Res 3: 408–410.
    • (2014) Transl Lung Cancer Res , vol.3 , pp. 408-410
    • Lee, S.1    Chow, L.2
  • 132
    • 84896495245 scopus 로고    scopus 로고
    • Immunologic response to the survivin-derived multi-epitope vaccine EMD 640744 in patients with advanced solid tumors
    • Lennerz V. Gross S. Gallerani E. Sessa C. Mach N. Boehm S. et al. (2014) Immunologic response to the survivin-derived multi-epitope vaccine EMD 640744 in patients with advanced solid tumors. Cancer Immunol Immunother 63: 381–394.
    • (2014) Cancer Immunol Immunother , vol.63 , pp. 381-394
    • Lennerz, V.1    Gross, S.2    Gallerani, E.3    Sessa, C.4    Mach, N.5    Boehm, S.6
  • 135
    • 84990001695 scopus 로고    scopus 로고
    • VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy
    • Lines J. Sempere L. Broughton T. Wang L. Noelle R. (2014 b) VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy. Cancer Immunol Res 2: 510–517.
    • (2014) Cancer Immunol Res , vol.2 , pp. 510-517
    • Lines, J.1    Sempere, L.2    Broughton, T.3    Wang, L.4    Noelle, R.5
  • 136
    • 84930208138 scopus 로고    scopus 로고
    • Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses
    • Liu J. Yuan Y. Chen W. Putra J. Suriawinata A. Schenk A. et al. (2015 a) Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses. Proc Natl Acad Sci U S A 112: 6682–6687.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. 6682-6687
    • Liu, J.1    Yuan, Y.2    Chen, W.3    Putra, J.4    Suriawinata, A.5    Schenk, A.6
  • 137
    • 84944739668 scopus 로고    scopus 로고
    • Safety and efficacy of MPDL3280A (anti-PD-L1) in combination with platinum-based doublet chemotherapy in patients with advanced non-small cell lung cancer (NSCLC)
    • abstract 8030.
    • Liu S. Powderly J. Camidge D. Ready N. Heist R. Hodi S. et al. (2015 b) Safety and efficacy of MPDL3280A (anti-PD-L1) in combination with platinum-based doublet chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). J Clin Oncol 33(Suppl.): abstract 8030.
    • (2015) J Clin Oncol , vol.33
    • Liu, S.1    Powderly, J.2    Camidge, D.3    Ready, N.4    Heist, R.5    Hodi, S.6
  • 138
    • 84925519872 scopus 로고    scopus 로고
    • Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia
    • Loke J. Khan J. Wilson J. Craddock C. Wheatley K. (2015) Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia. Ann Hematol 94: 361–373.
    • (2015) Ann Hematol , vol.94 , pp. 361-373
    • Loke, J.1    Khan, J.2    Wilson, J.3    Craddock, C.4    Wheatley, K.5
  • 139
    • 84945293157 scopus 로고    scopus 로고
    • Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy
    • DOI: 10.1177/1078155214538087
    • Lu J. Lee-Gabel L. Nadeau M. Ferencz T. Soefje S. (2014) Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy. J Oncol Pharm Pract. DOI: 10.1177/1078155214538087.
    • (2014) J Oncol Pharm Pract
    • Lu, J.1    Lee-Gabel, L.2    Nadeau, M.3    Ferencz, T.4    Soefje, S.5
  • 140
    • 79952055852 scopus 로고    scopus 로고
    • Immunological effects of bevacizumab-based treatment in metastatic colorectal cancer
    • Manzoni M. Rovati B. Ronzoni M. Loupakis F. Mariucci S. Ricci V. et al. (2010) Immunological effects of bevacizumab-based treatment in metastatic colorectal cancer. Oncology 79: 187–196.
    • (2010) Oncology , vol.79 , pp. 187-196
    • Manzoni, M.1    Rovati, B.2    Ronzoni, M.3    Loupakis, F.4    Mariucci, S.5    Ricci, V.6
  • 142
    • 80052206741 scopus 로고    scopus 로고
    • Phase III multicenter clinical trial of the sialyl-TN (STn)-keyhole limpet hemocyanin (KLH) vaccine for metastatic breast cancer
    • Miles D. Roche H. Martin M. Perren T. Cameron D. Glaspy J. et al. (2011) Phase III multicenter clinical trial of the sialyl-TN (STn)-keyhole limpet hemocyanin (KLH) vaccine for metastatic breast cancer. Oncologist 16: 1092–1100.
    • (2011) Oncologist , vol.16 , pp. 1092-1100
    • Miles, D.1    Roche, H.2    Martin, M.3    Perren, T.4    Cameron, D.5    Glaspy, J.6
  • 143
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller K. Wang M. Gralow J. Dickler M. Cobleigh M. Perez E. et al. (2007) Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 357: 2666–2676.
    • (2007) N Engl J Med , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3    Dickler, M.4    Cobleigh, M.5    Perez, E.6
  • 144
    • 84923296203 scopus 로고    scopus 로고
    • Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets
    • Mirandola L. Figueroa J. Phan T. Grizzi F. Kim M. Rahman R. et al. (2015) Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets. Oncotarget 6: 2812–2826.
    • (2015) Oncotarget , vol.6 , pp. 2812-2826
    • Mirandola, L.1    Figueroa, J.2    Phan, T.3    Grizzi, F.4    Kim, M.5    Rahman, R.6
  • 145
    • 84938077149 scopus 로고    scopus 로고
    • Tecemotide in unresectable stage III non-small-cell lung cancer in the phase III START study: updated overall survival and biomarker analyses
    • Mitchell P. Thatcher N. Socinski M. Wasilewska-Tesluk E. Horwood K. Szczesna A. et al. (2015) Tecemotide in unresectable stage III non-small-cell lung cancer in the phase III START study: updated overall survival and biomarker analyses. Ann Oncol 26: 1134–1142.
    • (2015) Ann Oncol , vol.26 , pp. 1134-1142
    • Mitchell, P.1    Thatcher, N.2    Socinski, M.3    Wasilewska-Tesluk, E.4    Horwood, K.5    Szczesna, A.6
  • 146
    • 84927724638 scopus 로고    scopus 로고
    • EBAG9 modulates host immune defense against tumor formation and metastasis by regulating cytotoxic activity of T lymphocytes
    • Miyazaki T. Ikeda K. Horie-Inoue K. Kondo T. Takahashi S. Inoue S. (2014) EBAG9 modulates host immune defense against tumor formation and metastasis by regulating cytotoxic activity of T lymphocytes. Oncogenesis 3: e126.
    • (2014) Oncogenesis , vol.3 , pp. e126
    • Miyazaki, T.1    Ikeda, K.2    Horie-Inoue, K.3    Kondo, T.4    Takahashi, S.5    Inoue, S.6
  • 147
    • 84893930312 scopus 로고    scopus 로고
    • Survivin as a preferential target for cancer therapy
    • Mobahat M. Narendran A. Riabowol K. (2014) Survivin as a preferential target for cancer therapy. Int J Mol Sci 15: 2494–2516.
    • (2014) Int J Mol Sci , vol.15 , pp. 2494-2516
    • Mobahat, M.1    Narendran, A.2    Riabowol, K.3
  • 148
    • 84873991752 scopus 로고    scopus 로고
    • Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
    • Morgan R. Chinnasamy N. Abate-Daga D. Gros A. Robbins P. Zheng Z. et al. (2013) Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. J Immunother 36: 133–151.
    • (2013) J Immunother , vol.36 , pp. 133-151
    • Morgan, R.1    Chinnasamy, N.2    Abate-Daga, D.3    Gros, A.4    Robbins, P.5    Zheng, Z.6
  • 149
    • 84880916286 scopus 로고    scopus 로고
    • Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients
    • Morse M. Chaudhry A. Gabitzsch E. Hobeika A. Osada T. Clay T. et al. (2013 a) Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients. Cancer Immunol Immunother 62: 1293–1301.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 1293-1301
    • Morse, M.1    Chaudhry, A.2    Gabitzsch, E.3    Hobeika, A.4    Osada, T.5    Clay, T.6
  • 150
    • 84888130428 scopus 로고    scopus 로고
    • A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC 1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer
    • Morse M. Niedzwiecki D. Marshall J. Garrett C. Chang D. Aklilu M. et al. (2013 b) A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC 1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer. Ann Surg 258: 879–886.
    • (2013) Ann Surg , vol.258 , pp. 879-886
    • Morse, M.1    Niedzwiecki, D.2    Marshall, J.3    Garrett, C.4    Chang, D.5    Aklilu, M.6
  • 151
    • 33748098860 scopus 로고    scopus 로고
    • PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and -gamma and mediates T cell apoptosis
    • Muhlbauer M. Fleck M. Schutz C. Weiss T. Froh M. Blank C. et al. (2006) PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and -gamma and mediates T cell apoptosis. J Hepatol 45: 520–528.
    • (2006) J Hepatol , vol.45 , pp. 520-528
    • Muhlbauer, M.1    Fleck, M.2    Schutz, C.3    Weiss, T.4    Froh, M.5    Blank, C.6
  • 152
    • 84879625854 scopus 로고    scopus 로고
    • New checkpoint inhibitors ride the immunotherapy tsunami
    • Mullard A. (2013) New checkpoint inhibitors ride the immunotherapy tsunami. Nat Rev Drug Discov 12: 489–492.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 489-492
    • Mullard, A.1
  • 153
    • 77049151988 scopus 로고
    • A review of the influence of bacterial infection and of bacterial products (Coley's toxins) on malignant tumors in man; a critical analysis of 30 inoperable cases treated by Coley's mixed toxins, in which diagnosis was confirmed by microscopic examination selected for special study
    • Nauts H. Fowler G. Bogatko F. (1953) A review of the influence of bacterial infection and of bacterial products (Coley's toxins) on malignant tumors in man; a critical analysis of 30 inoperable cases treated by Coley's mixed toxins, in which diagnosis was confirmed by microscopic examination selected for special study. Acta Med Scand Suppl 276: 1–103.
    • (1953) Acta Med Scand Suppl , vol.276 , pp. 1-103
    • Nauts, H.1    Fowler, G.2    Bogatko, F.3
  • 155
    • 79956103042 scopus 로고    scopus 로고
    • Anti-TIM3 antibody promotes T cell IFN-gamma-mediated antitumor immunity and suppresses established tumors
    • Ngiow S. von Scheidt B. Akiba H. Yagita H. Teng M. Smyth M. (2011) Anti-TIM3 antibody promotes T cell IFN-gamma-mediated antitumor immunity and suppresses established tumors. Cancer Res 71: 3540–3551.
    • (2011) Cancer Res , vol.71 , pp. 3540-3551
    • Ngiow, S.1    von Scheidt, B.2    Akiba, H.3    Yagita, H.4    Teng, M.5    Smyth, M.6
  • 156
    • 84925545111 scopus 로고    scopus 로고
    • Clinical blockade of PD 1 and LAG3–potential mechanisms of action
    • Nguyen L. Ohashi P. (2015) Clinical blockade of PD 1 and LAG3–potential mechanisms of action. Nat Rev Immunol 15: 45–56.
    • (2015) Nat Rev Immunol , vol.15 , pp. 45-56
    • Nguyen, L.1    Ohashi, P.2
  • 157
    • 33646083008 scopus 로고    scopus 로고
    • Directions in the immune targeting of cancer: lessons learned from the cancer-testis Ag NY-ESO-1
    • Nicholaou T. Ebert L. Davis I. Robson N. Klein O. Maraskovsky E. et al. (2006) Directions in the immune targeting of cancer: lessons learned from the cancer-testis Ag NY-ESO-1. Immunol Cell Biol 84: 303–317.
    • (2006) Immunol Cell Biol , vol.84 , pp. 303-317
    • Nicholaou, T.1    Ebert, L.2    Davis, I.3    Robson, N.4    Klein, O.5    Maraskovsky, E.6
  • 158
    • 63549100184 scopus 로고    scopus 로고
    • Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMATRIX vaccine in patients with advanced malignant melanoma
    • Nicholaou T. Ebert L. Davis I. McArthur G. Jackson H. Dimopoulos N. et al. (2009) Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMATRIX vaccine in patients with advanced malignant melanoma. Clin Cancer Res 15: 2166–2173.
    • (2009) Clin Cancer Res , vol.15 , pp. 2166-2173
    • Nicholaou, T.1    Ebert, L.2    Davis, I.3    McArthur, G.4    Jackson, H.5    Dimopoulos, N.6
  • 159
    • 84866325625 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition under control: global programs to regulate epithelial plasticity
    • Nieto M. Cano A. (2012) The epithelial-mesenchymal transition under control: global programs to regulate epithelial plasticity. Semin Cancer Biol 22: 361–368.
    • (2012) Semin Cancer Biol , vol.22 , pp. 361-368
    • Nieto, M.1    Cano, A.2
  • 160
    • 84896445780 scopus 로고    scopus 로고
    • Pertuzumab and its accelerated approval: evolving treatment paradigms and new challenges in the management of HER2-positive breast cancer
    • O'Sullivan C. Connolly R. (2014) Pertuzumab and its accelerated approval: evolving treatment paradigms and new challenges in the management of HER2-positive breast cancer. Oncology (Williston Park) 28: 186–194.
    • (2014) Oncology (Williston Park) , vol.28 , pp. 186-194
    • O'Sullivan, C.1    Connolly, R.2
  • 161
    • 84859588335 scopus 로고    scopus 로고
    • Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients
    • Odunsi K. Matsuzaki J. Karbach J. Neumann A. Mhawech-Fauceglia P. Miller A. et al. (2012) Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients. Proc Natl Acad Sci U S A 109: 5797–5802.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 5797-5802
    • Odunsi, K.1    Matsuzaki, J.2    Karbach, J.3    Neumann, A.4    Mhawech-Fauceglia, P.5    Miller, A.6
  • 162
    • 84918530942 scopus 로고    scopus 로고
    • A peptide antigen derived from EGFR T790M is immunogenic in nonsmall cell lung cancer
    • Ofuji K. Tada Y. Yoshikawa T. Shimomura M. Yoshimura M. Saito K. et al. (2015) A peptide antigen derived from EGFR T790M is immunogenic in nonsmall cell lung cancer. Int J Oncol 46: 497–504.
    • (2015) Int J Oncol , vol.46 , pp. 497-504
    • Ofuji, K.1    Tada, Y.2    Yoshikawa, T.3    Shimomura, M.4    Yoshimura, M.5    Saito, K.6
  • 163
    • 84865778255 scopus 로고    scopus 로고
    • Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer
    • Okabayashi K. Fujita T. Miyazaki J. Okada T. Iwata T. Hirao N. et al. (2012) Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer. Cancer Sci 103: 1617–1624.
    • (2012) Cancer Sci , vol.103 , pp. 1617-1624
    • Okabayashi, K.1    Fujita, T.2    Miyazaki, J.3    Okada, T.4    Iwata, T.5    Hirao, N.6
  • 164
    • 84920969943 scopus 로고    scopus 로고
    • Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC
    • Okada H. Butterfield L. Hamilton R. Hoji A. Sakaki M. Ahn B. et al. (2015) Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC. Clin Cancer Res 21: 286–294.
    • (2015) Clin Cancer Res , vol.21 , pp. 286-294
    • Okada, H.1    Butterfield, L.2    Hamilton, R.3    Hoji, A.4    Sakaki, M.5    Ahn, B.6
  • 166
    • 18244371651 scopus 로고    scopus 로고
    • Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
    • Pao W. Miller V. Politi K. Riely G. Somwar R. Zakowski M. et al. (2005) Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2: e73.
    • (2005) PLoS Med , vol.2 , pp. e73
    • Pao, W.1    Miller, V.2    Politi, K.3    Riely, G.4    Somwar, R.5    Zakowski, M.6
  • 167
    • 84924971683 scopus 로고    scopus 로고
    • Necitumumab plus pemetrexed and cisplatin as first-line therapy in patients with stage IV non-squamous non-small-cell lung cancer (INSPIRE): an open-label, randomised, controlled phase 3 study
    • Paz-Ares L. Mezger J. Ciuleanu T. Fischer J. von Pawel J. Provencio M. et al. (2015) Necitumumab plus pemetrexed and cisplatin as first-line therapy in patients with stage IV non-squamous non-small-cell lung cancer (INSPIRE): an open-label, randomised, controlled phase 3 study. Lancet Oncol 16: 328–337.
    • (2015) Lancet Oncol , vol.16 , pp. 328-337
    • Paz-Ares, L.1    Mezger, J.2    Ciuleanu, T.3    Fischer, J.4    von Pawel, J.5    Provencio, M.6
  • 168
    • 80052728749 scopus 로고    scopus 로고
    • Four-year follow-up of trastuzumab plus adjuvant chemotherapy for operable human epidermal growth factor receptor 2-positive breast cancer: joint analysis of data from NCCTG N 9831 and NSABP B-31
    • Perez E. Romond E. Suman V. Jeong J. Davidson N. Geyer C. Jr. et al. (2011) Four-year follow-up of trastuzumab plus adjuvant chemotherapy for operable human epidermal growth factor receptor 2-positive breast cancer: joint analysis of data from NCCTG N 9831 and NSABP B-31. J Clin Oncol 29: 3366–3373.
    • (2011) J Clin Oncol , vol.29 , pp. 3366-3373
    • Perez, E.1    Romond, E.2    Suman, V.3    Jeong, J.4    Davidson, N.5    Geyer, C.6
  • 169
    • 84911908120 scopus 로고    scopus 로고
    • Trastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2-positive breast cancer: planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831
    • Perez E. Romond E. Suman V. Jeong J. Sledge G. Geyer C. Jr. et al. (2014) Trastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2-positive breast cancer: planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831. J Clin Oncol 32: 3744–3752.
    • (2014) J Clin Oncol , vol.32 , pp. 3744-3752
    • Perez, E.1    Romond, E.2    Suman, V.3    Jeong, J.4    Sledge, G.5    Geyer, C.6
  • 170
    • 84947287356 scopus 로고    scopus 로고
    • A phase Ia study of MPDL3280A (anti-PD-L1): updated response and survival data in urothelial bladder cancer (UBC)
    • abstract 4501.
    • Petrylak D. Powles T. Bellmunt J. Braiteh F. Loriot Y. Zambrano C. et al. (2015) A phase Ia study of MPDL3280A (anti-PD-L1): updated response and survival data in urothelial bladder cancer (UBC). J Clin Oncol 33(Suppl.): abstract 4501.
    • (2015) J Clin Oncol , vol.33
    • Petrylak, D.1    Powles, T.2    Bellmunt, J.3    Braiteh, F.4    Loriot, Y.5    Zambrano, C.6
  • 171
    • 84901485155 scopus 로고    scopus 로고
    • Adenosine A2A receptor antagonists in Parkinson's disease: progress in clinical trials from the newly approved istradefylline to drugs in early development and those already discontinued
    • Pinna A. (2014) Adenosine A2A receptor antagonists in Parkinson's disease: progress in clinical trials from the newly approved istradefylline to drugs in early development and those already discontinued. CNS Drugs 28: 455–474.
    • (2014) CNS Drugs , vol.28 , pp. 455-474
    • Pinna, A.1
  • 172
    • 84951792922 scopus 로고    scopus 로고
    • A phase III study of MEDI 4736 (M), an anti-PD-L1 antibody, in monotherapy or in combination with tremelimumab (T), versus standard of care (SOC) in patients (pts) with advanced non-small cell lung cancer (NSCLC) who have received at least two prior systemic treatment regimens (ARCTIC)
    • abstract TPS8104.
    • Planchard D. Shtivelband M. Shi K. Ibrahim R. Ballas M. Sorio J. et al. (2015) A phase III study of MEDI 4736 (M), an anti-PD-L1 antibody, in monotherapy or in combination with tremelimumab (T), versus standard of care (SOC) in patients (pts) with advanced non-small cell lung cancer (NSCLC) who have received at least two prior systemic treatment regimens (ARCTIC). J Clin Oncol 33(Suppl.): abstract TPS8104.
    • (2015) J Clin Oncol , vol.33
    • Planchard, D.1    Shtivelband, M.2    Shi, K.3    Ibrahim, R.4    Ballas, M.5    Sorio, J.6
  • 173
    • 84905817445 scopus 로고    scopus 로고
    • Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas
    • Pollack I. Jakacki R. Butterfield L. Hamilton R. Panigrahy A. Potter D. et al. (2014) Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas. J Clin Oncol 32: 2050–2058.
    • (2014) J Clin Oncol , vol.32 , pp. 2050-2058
    • Pollack, I.1    Jakacki, R.2    Butterfield, L.3    Hamilton, R.4    Panigrahy, A.5    Potter, D.6
  • 175
    • 84923078390 scopus 로고    scopus 로고
    • MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
    • Powles T. Eder J. Fine G. Braiteh F. Loriot Y. Cruz C. et al. (2014) MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature 515: 558–562.
    • (2014) Nature , vol.515 , pp. 558-562
    • Powles, T.1    Eder, J.2    Fine, G.3    Braiteh, F.4    Loriot, Y.5    Cruz, C.6
  • 176
    • 70449193189 scopus 로고
    • Immunity to methylcholanthrene-induced sarcomas
    • Prehn R. Main J. (1957) Immunity to methylcholanthrene-induced sarcomas. J Natl Cancer Inst 18: 769–778.
    • (1957) J Natl Cancer Inst , vol.18 , pp. 769-778
    • Prehn, R.1    Main, J.2
  • 177
    • 84899981129 scopus 로고    scopus 로고
    • Panitumumab versus cetuximab in patients with chemotherapy-refractory wild-type KRAS exon 2 metastatic colorectal cancer (ASPECCT): a randomised, multicentre, open-label, non-inferiority phase 3 study
    • Price T. Peeters M. Kim T. Li J. Cascinu S. Ruff P. et al. (2014) Panitumumab versus cetuximab in patients with chemotherapy-refractory wild-type KRAS exon 2 metastatic colorectal cancer (ASPECCT): a randomised, multicentre, open-label, non-inferiority phase 3 study. Lancet Oncol 15: 569–579.
    • (2014) Lancet Oncol , vol.15 , pp. 569-579
    • Price, T.1    Peeters, M.2    Kim, T.3    Li, J.4    Cascinu, S.5    Ruff, P.6
  • 178
    • 84899837376 scopus 로고    scopus 로고
    • Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: The AURELIA open-label randomized phase III trial
    • Pujade-Lauraine E. Hilpert F. Weber B. Reuss A. Poveda A. Kristensen G. et al. (2014) Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: The AURELIA open-label randomized phase III trial. J Clin Oncol 32: 1302–1308.
    • (2014) J Clin Oncol , vol.32 , pp. 1302-1308
    • Pujade-Lauraine, E.1    Hilpert, F.2    Weber, B.3    Reuss, A.4    Poveda, A.5    Kristensen, G.6
  • 179
    • 84892844284 scopus 로고    scopus 로고
    • Meta-analysis of individual patient data from randomized trials of chemotherapy plus cetuximab as first-line treatment for advanced non-small cell lung cancer
    • Pujol J. Pirker R. Lynch T. Butts C. Rosell R. Shepherd F. et al. (2014) Meta-analysis of individual patient data from randomized trials of chemotherapy plus cetuximab as first-line treatment for advanced non-small cell lung cancer. Lung Cancer 83: 211–218.
    • (2014) Lung Cancer , vol.83 , pp. 211-218
    • Pujol, J.1    Pirker, R.2    Lynch, T.3    Butts, C.4    Rosell, R.5    Shepherd, F.6
  • 180
    • 49249109608 scopus 로고    scopus 로고
    • Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study
    • Raetz E. Cairo M. Borowitz M. Blaney S. Krailo M. Leil T. et al. (2008) Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study. J Clin Oncol 26: 3756–3762.
    • (2008) J Clin Oncol , vol.26 , pp. 3756-3762
    • Raetz, E.1    Cairo, M.2    Borowitz, M.3    Blaney, S.4    Krailo, M.5    Leil, T.6
  • 181
    • 84929518915 scopus 로고    scopus 로고
    • Re-induction chemoimmunotherapy with epratuzumab in relapsed acute lymphoblastic leukemia (ALL): phase II results from Children's Oncology Group (COG) study ADVL04P2
    • Raetz E. Cairo M. Borowitz M. Lu X. Devidas M. Reid J. et al. (2015) Re-induction chemoimmunotherapy with epratuzumab in relapsed acute lymphoblastic leukemia (ALL): phase II results from Children's Oncology Group (COG) study ADVL04P2. Pediatr Blood Cancer 62: 1171–1175.
    • (2015) Pediatr Blood Cancer , vol.62 , pp. 1171-1175
    • Raetz, E.1    Cairo, M.2    Borowitz, M.3    Lu, X.4    Devidas, M.5    Reid, J.6
  • 182
    • 84951775278 scopus 로고    scopus 로고
    • Phase II study to evaluate the clinical efficacy and safety of MEDI 4736 in patients with glioblastoma (GBM)
    • abstract TPS2077.
    • Reardon D. Dietrich J. Kaley T. Gan H. Dunn G. Cloughesy T. et al. (2015) Phase II study to evaluate the clinical efficacy and safety of MEDI 4736 in patients with glioblastoma (GBM). J Clin Oncol 33(Suppl.): abstract TPS2077.
    • (2015) J Clin Oncol , vol.33
    • Reardon, D.1    Dietrich, J.2    Kaley, T.3    Gan, H.4    Dunn, G.5    Cloughesy, T.6
  • 183
    • 84901980428 scopus 로고    scopus 로고
    • Cancer-testis antigen MAGE-C2/CT10 induces spontaneous CD4+ and CD8+ T-cell responses in multiple myeloma patients
    • Reinhard H. Yousef S. Luetkens T. Fehse B. Berdien B. Kroger N. et al. (2014) Cancer-testis antigen MAGE-C2/CT10 induces spontaneous CD4+ and CD8+ T-cell responses in multiple myeloma patients. Blood Cancer J 4: e212.
    • (2014) Blood Cancer J , vol.4 , pp. e212
    • Reinhard, H.1    Yousef, S.2    Luetkens, T.3    Fehse, B.4    Berdien, B.5    Kroger, N.6
  • 184
    • 84874605864 scopus 로고    scopus 로고
    • Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
    • Ribas A. Kefford R. Marshall M. Punt C. Haanen J. Marmol M. et al. (2013) Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J Clin Oncol 31: 616–622.
    • (2013) J Clin Oncol , vol.31 , pp. 616-622
    • Ribas, A.1    Kefford, R.2    Marshall, M.3    Punt, C.4    Haanen, J.5    Marmol, M.6
  • 185
    • 79952304769 scopus 로고    scopus 로고
    • Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
    • Robbins P. Morgan R. Feldman S. Yang J. Sherry R. Dudley M. et al. (2011) Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. J Clin Oncol 29: 917–924.
    • (2011) J Clin Oncol , vol.29 , pp. 917-924
    • Robbins, P.1    Morgan, R.2    Feldman, S.3    Yang, J.4    Sherry, R.5    Dudley, M.6
  • 186
    • 84925222119 scopus 로고    scopus 로고
    • Nivolumab in previously untreated melanoma without BRAF mutation
    • Robert C. Long G. Brady B. Dutriaux C. Maio M. Mortier L. et al. (2015 a) Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med 372: 320–330.
    • (2015) N Engl J Med , vol.372 , pp. 320-330
    • Robert, C.1    Long, G.2    Brady, B.3    Dutriaux, C.4    Maio, M.5    Mortier, L.6
  • 187
    • 84908354848 scopus 로고    scopus 로고
    • Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
    • Robert C. Ribas A. Wolchok J. Hodi F. Hamid O. Kefford R. et al. (2014) Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 384: 1109–1117.
    • (2014) Lancet , vol.384 , pp. 1109-1117
    • Robert, C.1    Ribas, A.2    Wolchok, J.3    Hodi, F.4    Hamid, O.5    Kefford, R.6
  • 189
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C. Thomas L. Bondarenko I. O'Day S. Weber J. Garbe C. et al. (2011) Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 364: 2517–2526.
    • (2011) N Engl J Med , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3    O'Day, S.4    Weber, J.5    Garbe, C.6
  • 190
    • 84899083535 scopus 로고    scopus 로고
    • MART-1 peptide vaccination plus IMP 321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a phase I trial
    • Romano E. Michielin O. Voelter V. Laurent J. Bichat H. Stravodimou A. et al. (2014) MART-1 peptide vaccination plus IMP 321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a phase I trial. J Transl Med 12: 97.
    • (2014) J Transl Med , vol.12 , pp. 97
    • Romano, E.1    Michielin, O.2    Voelter, V.3    Laurent, J.4    Bichat, H.5    Stravodimou, A.6
  • 191
    • 26844536978 scopus 로고    scopus 로고
    • Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    • Romond E. Perez E. Bryant J. Suman V. Geyer C. Jr. Davidson N. et al. (2005) Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 353: 1673–1684.
    • (2005) N Engl J Med , vol.353 , pp. 1673-1684
    • Romond, E.1    Perez, E.2    Bryant, J.3    Suman, V.4    Geyer, C.5    Davidson, N.6
  • 192
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • Rosenberg S. (2001) Progress in human tumour immunology and immunotherapy. Nature 411: 380–384.
    • (2001) Nature , vol.411 , pp. 380-384
    • Rosenberg, S.1
  • 193
    • 84921714339 scopus 로고    scopus 로고
    • TroVax in colorectal cancer
    • Rowe J. Cen P. (2014) TroVax in colorectal cancer. Hum Vaccin Immunother 10: 3196–3200.
    • (2014) Hum Vaccin Immunother , vol.10 , pp. 3196-3200
    • Rowe, J.1    Cen, P.2
  • 194
    • 84904227995 scopus 로고    scopus 로고
    • Immunotherapeutic agents in non-small-cell lung cancer finally coming to the front lines
    • Ruiz R. Hunis B. Raez L. (2014) Immunotherapeutic agents in non-small-cell lung cancer finally coming to the front lines. Curr Oncol Rep 16: 400.
    • (2014) Curr Oncol Rep , vol.16 , pp. 400
    • Ruiz, R.1    Hunis, B.2    Raez, L.3
  • 196
    • 77957744369 scopus 로고    scopus 로고
    • Targeting tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
    • Sakuishi K. Apetoh L. Sullivan J. Blazar B. Kuchroo V. Anderson A. (2010) Targeting tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 207: 2187–2194.
    • (2010) J Exp Med , vol.207 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.3    Blazar, B.4    Kuchroo, V.5    Anderson, A.6
  • 197
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • Saltz L. Meropol N. Loehrer P. Needle M. Sr. Kopit J. Mayer R. (2004) Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 22: 1201–1208.
    • (2004) J Clin Oncol , vol.22 , pp. 1201-1208
    • Saltz, L.1    Meropol, N.2    Loehrer, P.3    Needle, M.4    Kopit, J.5    Mayer, R.6
  • 198
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A. Gray R. Perry M. Brahmer J. Schiller J. Dowlati A. et al. (2006) Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 355: 2542–2550.
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.3    Brahmer, J.4    Schiller, J.5    Dowlati, A.6
  • 199
    • 84872529363 scopus 로고    scopus 로고
    • Long-term tumor regression induced by an antibody–drug conjugate that targets 5T4, an oncofetal antigen expressed on tumor-initiating cells
    • Sapra P. Damelin M. Dijoseph J. Marquette K. Geles K. Golas J. et al. (2013) Long-term tumor regression induced by an antibody–drug conjugate that targets 5T4, an oncofetal antigen expressed on tumor-initiating cells. Mol Cancer Ther 12: 38–47.
    • (2013) Mol Cancer Ther , vol.12 , pp. 38-47
    • Sapra, P.1    Damelin, M.2    Dijoseph, J.3    Marquette, K.4    Geles, K.5    Golas, J.6
  • 200
    • 84897953576 scopus 로고    scopus 로고
    • Shaping the repertoire of tumor-infiltrating effector and regulatory T cells
    • Savage P. Leventhal D. Malchow S. (2014) Shaping the repertoire of tumor-infiltrating effector and regulatory T cells. Immunol Rev 259: 245–258.
    • (2014) Immunol Rev , vol.259 , pp. 245-258
    • Savage, P.1    Leventhal, D.2    Malchow, S.3
  • 201
    • 84896736403 scopus 로고    scopus 로고
    • Identification of HLA-A2 or HLA-A24-restricted CTL epitopes for potential HSP105-targeted immunotherapy in colorectal cancer
    • Sawada Y. Komori H. Tsunoda Y. Shimomura M. Takahashi M. Baba H. et al. (2014) Identification of HLA-A2 or HLA-A24-restricted CTL epitopes for potential HSP105-targeted immunotherapy in colorectal cancer. Oncol Rep 31: 1051–1058.
    • (2014) Oncol Rep , vol.31 , pp. 1051-1058
    • Sawada, Y.1    Komori, H.2    Tsunoda, Y.3    Shimomura, M.4    Takahashi, M.5    Baba, H.6
  • 202
    • 84865506979 scopus 로고    scopus 로고
    • Rationale and design of MARQUEE: a phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer
    • Scagliotti G. Novello S. Schiller J. Hirsh V. Sequist L. Soria J. et al. (2012) Rationale and design of MARQUEE: a phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer. Clin Lung Cancer 13: 391–395.
    • (2012) Clin Lung Cancer , vol.13 , pp. 391-395
    • Scagliotti, G.1    Novello, S.2    Schiller, J.3    Hirsh, V.4    Sequist, L.5    Soria, J.6
  • 203
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
    • Schreiber R. Old L. Smyth M. (2011) Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 331: 1565–1570.
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.1    Old, L.2    Smyth, M.3
  • 204
  • 206
    • 84939263031 scopus 로고    scopus 로고
    • Nivolumab: a review in advanced melanoma
    • Scott L. (2015) Nivolumab: a review in advanced melanoma. Drugs 75: 1413–1424.
    • (2015) Drugs , vol.75 , pp. 1413-1424
    • Scott, L.1
  • 207
    • 83655196673 scopus 로고    scopus 로고
    • Novel monoclonal antibodies for cancer treatment: the trifunctional antibody catumaxomab (removab)
    • Seimetz D. (2011) Novel monoclonal antibodies for cancer treatment: the trifunctional antibody catumaxomab (removab). J Cancer 2: 309–316.
    • (2011) J Cancer , vol.2 , pp. 309-316
    • Seimetz, D.1
  • 208
    • 84931053950 scopus 로고    scopus 로고
    • Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy
    • Shabani M. Naseri J. Shokri F. (2015) Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy. Expert Opin Ther Targets 19: 941–955.
    • (2015) Expert Opin Ther Targets , vol.19 , pp. 941-955
    • Shabani, M.1    Naseri, J.2    Shokri, F.3
  • 209
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • Shankaran V. Ikeda H. Bruce A. White J. Swanson P. Old L. et al. (2001) IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410: 1107–1111.
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.3    White, J.4    Swanson, P.5    Old, L.6
  • 210
    • 33847205332 scopus 로고    scopus 로고
    • A phase II study of a 5T4 oncofoetal antigen tumour-targeted superantigen (ABR-214936) therapy in patients with advanced renal cell carcinoma
    • Shaw D. Connolly N. Patel P. Kilany S. Hedlund G. Nordle O. et al. (2007) A phase II study of a 5T4 oncofoetal antigen tumour-targeted superantigen (ABR-214936) therapy in patients with advanced renal cell carcinoma. Br J Cancer 96: 567–574.
    • (2007) Br J Cancer , vol.96 , pp. 567-574
    • Shaw, D.1    Connolly, N.2    Patel, P.3    Kilany, S.4    Hedlund, G.5    Nordle, O.6
  • 211
    • 84899496281 scopus 로고    scopus 로고
    • PROSTVAC(R) targeted immunotherapy candidate for prostate cancer
    • Shore N. (2014) PROSTVAC(R) targeted immunotherapy candidate for prostate cancer. Immunotherapy 6: 235–247.
    • (2014) Immunotherapy , vol.6 , pp. 235-247
    • Shore, N.1
  • 212
    • 78650208859 scopus 로고    scopus 로고
    • The CD4-like molecule LAG-3, biology and therapeutic applications
    • Sierro S. Romero P. Speiser D. (2011) The CD4-like molecule LAG-3, biology and therapeutic applications. Expert Opin Ther Targets 15: 91–101.
    • (2011) Expert Opin Ther Targets , vol.15 , pp. 91-101
    • Sierro, S.1    Romero, P.2    Speiser, D.3
  • 213
    • 84938488864 scopus 로고    scopus 로고
    • Development of PROSTVAC immunotherapy in prostate cancer
    • Singh P. Pal S. Alex A. Agarwal N. (2015) Development of PROSTVAC immunotherapy in prostate cancer. Future Oncol 11: 2137–2148.
    • (2015) Future Oncol , vol.11 , pp. 2137-2148
    • Singh, P.1    Pal, S.2    Alex, A.3    Agarwal, N.4
  • 215
    • 37049183697 scopus 로고
    • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon D. Clark G. Wong S. Levin W. Ullrich A. McGuire W. (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235: 177–182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.1    Clark, G.2    Wong, S.3    Levin, W.4    Ullrich, A.5    McGuire, W.6
  • 216
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon D. Godolphin W. Jones L. Holt J. Wong S. Keith D. et al. (1989) Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244: 707–712.
    • (1989) Science , vol.244 , pp. 707-712
    • Slamon, D.1    Godolphin, W.2    Jones, L.3    Holt, J.4    Wong, S.5    Keith, D.6
  • 217
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER 2 for metastatic breast cancer that overexpresses HER2
    • Slamon D. Leyland-Jones B. Shak S. Fuchs H. Paton V. Bajamonde A. et al. (2001) Use of chemotherapy plus a monoclonal antibody against HER 2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344: 783–792.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.1    Leyland-Jones, B.2    Shak, S.3    Fuchs, H.4    Paton, V.5    Bajamonde, A.6
  • 218
    • 84883821225 scopus 로고    scopus 로고
    • Antibody therapeutics in cancer
    • Sliwkowski M. Mellman I. (2013) Antibody therapeutics in cancer. Science 341: 1192–1198.
    • (2013) Science , vol.341 , pp. 1192-1198
    • Sliwkowski, M.1    Mellman, I.2
  • 219
    • 80155131086 scopus 로고    scopus 로고
    • Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer
    • Smith H. Cronk R. Lang J. McNeel D. (2011) Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer. Cancer Res 71: 6785–6795.
    • (2011) Cancer Res , vol.71 , pp. 6785-6795
    • Smith, H.1    Cronk, R.2    Lang, J.3    McNeel, D.4
  • 220
    • 44249111440 scopus 로고    scopus 로고
    • EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer
    • Sobrero A. Maurel J. Fehrenbacher L. Scheithauer W. Abubakr Y. Lutz M. et al. (2008) EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. J Clin Oncol 26: 2311–2319.
    • (2008) J Clin Oncol , vol.26 , pp. 2311-2319
    • Sobrero, A.1    Maurel, J.2    Fehrenbacher, L.3    Scheithauer, W.4    Abubakr, Y.5    Lutz, M.6
  • 221
    • 84908005764 scopus 로고    scopus 로고
    • A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors
    • Soliman H. Jackson E. Neuger T. Dees E. Harvey R. Han H. et al. (2014) A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors. Oncotarget 5: 8136–8146.
    • (2014) Oncotarget , vol.5 , pp. 8136-8146
    • Soliman, H.1    Jackson, E.2    Neuger, T.3    Dees, E.4    Harvey, R.5    Han, H.6
  • 222
    • 0025109257 scopus 로고
    • Immunohistological distribution of 5T4 antigen in normal and malignant tissues
    • Southall P. Boxer G. Bagshawe K. Hole N. Bromley M. Stern P. (1990) Immunohistological distribution of 5T4 antigen in normal and malignant tissues. Br J Cancer 61: 89–95.
    • (1990) Br J Cancer , vol.61 , pp. 89-95
    • Southall, P.1    Boxer, G.2    Bagshawe, K.3    Hole, N.4    Bromley, M.5    Stern, P.6
  • 223
    • 84947444410 scopus 로고    scopus 로고
    • Clinical activity and safety from a phase II study (FIR) of MPDL3280A (anti-PD-L1) in PD-L1-selected patients with non-small cell lung cancer (NSCLC)
    • abstract 8028.
    • Spigel D. Chaft J. Gettinger S. Chao B. Dirix L. Schmid P. et al. (2015) Clinical activity and safety from a phase II study (FIR) of MPDL3280A (anti-PD-L1) in PD-L1-selected patients with non-small cell lung cancer (NSCLC). J Clin Oncol 33(Suppl.): abstract 8028.
    • (2015) J Clin Oncol , vol.33
    • Spigel, D.1    Chaft, J.2    Gettinger, S.3    Chao, B.4    Dirix, L.5    Schmid, P.6
  • 224
    • 84890108571 scopus 로고    scopus 로고
    • Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer
    • Spigel D. Ervin T. Ramlau R. Daniel D. Goldschmidt J. Jr. Blumenschein G. Jr. et al. (2013) Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer. J Clin Oncol 31: 4105–4114.
    • (2013) J Clin Oncol , vol.31 , pp. 4105-4114
    • Spigel, D.1    Ervin, T.2    Ramlau, R.3    Daniel, D.4    Goldschmidt, J.5    Blumenschein, G.6
  • 225
    • 84942138309 scopus 로고    scopus 로고
    • Efficacy, safety and predictive biomarker results from a randomized phase II study comparing MPDL3280A versus docetaxel in 2L/3L NSCLC (POPLAR)
    • abstract 8010.
    • Spira A. Park K. Mazieres J. Vansteenkiste J. Rittmeyer A. Ballinger M. et al. (2015) Efficacy, safety and predictive biomarker results from a randomized phase II study comparing MPDL3280A versus docetaxel in 2L/3L NSCLC (POPLAR). J Clin Oncol 33(Suppl.): abstract 8010.
    • (2015) J Clin Oncol , vol.33
    • Spira, A.1    Park, K.2    Mazieres, J.3    Vansteenkiste, J.4    Rittmeyer, A.5    Ballinger, M.6
  • 226
    • 84904392184 scopus 로고    scopus 로고
    • Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients
    • Staff C. Mozaffari F. Frodin J. Mellstedt H. Liljefors M. (2014) Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients. Int J Oncol 45: 1293–1303.
    • (2014) Int J Oncol , vol.45 , pp. 1293-1303
    • Staff, C.1    Mozaffari, F.2    Frodin, J.3    Mellstedt, H.4    Liljefors, M.5
  • 227
    • 79955570584 scopus 로고    scopus 로고
    • Anti-ErbB-2 m Ab therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 m Ab therapy
    • Stagg J. Loi S. Divisekera U. Ngiow S. Duret H. Yagita H. et al. (2011) Anti-ErbB-2 m Ab therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 m Ab therapy. Proc Natl Acad Sci U S A 108: 7142–7147.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 7142-7147
    • Stagg, J.1    Loi, S.2    Divisekera, U.3    Ngiow, S.4    Duret, H.5    Yagita, H.6
  • 228
    • 84927577635 scopus 로고    scopus 로고
    • Understanding and exploiting 5T4 oncofoetal glycoprotein expression
    • Stern P. Brazzatti J. Sawan S. McGinn O. (2014) Understanding and exploiting 5T4 oncofoetal glycoprotein expression. Semin Cancer Biol 29: 13–20.
    • (2014) Semin Cancer Biol , vol.29 , pp. 13-20
    • Stern, P.1    Brazzatti, J.2    Sawan, S.3    McGinn, O.4
  • 229
    • 84908159570 scopus 로고    scopus 로고
    • Novel agents in development for advanced non-small cell lung cancer
    • Stinchcombe T. (2014) Novel agents in development for advanced non-small cell lung cancer. Ther Adv Med Oncol 6: 240–253.
    • (2014) Ther Adv Med Oncol , vol.6 , pp. 240-253
    • Stinchcombe, T.1
  • 231
    • 84923090047 scopus 로고    scopus 로고
    • Disialoganglioside GD 2 as a therapeutic target for human diseases
    • Suzuki M. Cheung N. (2015) Disialoganglioside GD 2 as a therapeutic target for human diseases. Expert Opin Ther Targets 19: 349–362.
    • (2015) Expert Opin Ther Targets , vol.19 , pp. 349-362
    • Suzuki, M.1    Cheung, N.2
  • 232
    • 84930730522 scopus 로고    scopus 로고
    • Current state of anti-PD-L1 and anti-PD-1 agents in cancer therapy
    • Swaika A. Hammond W. Joseph R. (2015) Current state of anti-PD-L1 and anti-PD-1 agents in cancer therapy. Mol Immunol 67: 4–17.
    • (2015) Mol Immunol , vol.67 , pp. 4-17
    • Swaika, A.1    Hammond, W.2    Joseph, R.3
  • 233
    • 0037209078 scopus 로고    scopus 로고
    • MUC1 expression in lung cancer
    • Szabo E. (2003) MUC1 expression in lung cancer. Methods Mol Med 74: 251–258.
    • (2003) Methods Mol Med , vol.74 , pp. 251-258
    • Szabo, E.1
  • 234
    • 84859909667 scopus 로고    scopus 로고
    • Safety and immunogenicity of vaccination with MART-1 (26–35, 27L), gp 100 (209–217, 210M), and tyrosinase (368–376, 370D) in adjuvant with PF-3512676 and GM-CSF in metastatic melanoma
    • Tarhini A. Leng S. Moschos S. Yin Y. Sander C. Lin Y. et al. (2012) Safety and immunogenicity of vaccination with MART-1 (26–35, 27L), gp 100 (209–217, 210M), and tyrosinase (368–376, 370D) in adjuvant with PF-3512676 and GM-CSF in metastatic melanoma. J Immunother 35: 359–366.
    • (2012) J Immunother , vol.35 , pp. 359-366
    • Tarhini, A.1    Leng, S.2    Moschos, S.3    Yin, Y.4    Sander, C.5    Lin, Y.6
  • 235
    • 84872593848 scopus 로고    scopus 로고
    • VEGFA-VEGFR pathway blockade inhibits tumor-induced regulatory T-cell proliferation in colorectal cancer
    • Terme M. Pernot S. Marcheteau E. Sandoval F. Benhamouda N. Colussi O. et al. (2013) VEGFA-VEGFR pathway blockade inhibits tumor-induced regulatory T-cell proliferation in colorectal cancer. Cancer Res 73: 539–549.
    • (2013) Cancer Res , vol.73 , pp. 539-549
    • Terme, M.1    Pernot, S.2    Marcheteau, E.3    Sandoval, F.4    Benhamouda, N.5    Colussi, O.6
  • 236
  • 237
    • 84937518476 scopus 로고    scopus 로고
    • Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomised, controlled phase 3 trial
    • Thatcher N. Hirsch F. Luft A. Szczesna A. Ciuleanu T. Dediu M. et al. (2015) Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomised, controlled phase 3 trial. Lancet Oncol 16: 763–774.
    • (2015) Lancet Oncol , vol.16 , pp. 763-774
    • Thatcher, N.1    Hirsch, F.2    Luft, A.3    Szczesna, A.4    Ciuleanu, T.5    Dediu, M.6
  • 239
    • 84898973055 scopus 로고    scopus 로고
    • Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
    • Topalian S. Sznol M. McDermott D. Kluger H. Carvajal R. Sharfman W. et al. (2014) Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol 32: 1020–1030.
    • (2014) J Clin Oncol , vol.32 , pp. 1020-1030
    • Topalian, S.1    Sznol, M.2    McDermott, D.3    Kluger, H.4    Carvajal, R.5    Sharfman, W.6
  • 241
    • 84867563910 scopus 로고    scopus 로고
    • Carcinoembryonic antigen (CEA)-based cancer vaccines: recent patents and antitumor effects from experimental models to clinical trials
    • Turriziani M. Fantini M. Benvenuto M. Izzi V. Masuelli L. Sacchetti P. et al. (2012) Carcinoembryonic antigen (CEA)-based cancer vaccines: recent patents and antitumor effects from experimental models to clinical trials. Recent Pat Anticancer Drug Discov 7: 265–296.
    • (2012) Recent Pat Anticancer Drug Discov , vol.7 , pp. 265-296
    • Turriziani, M.1    Fantini, M.2    Benvenuto, M.3    Izzi, V.4    Masuelli, L.5    Sacchetti, P.6
  • 243
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
    • Uyttenhove C. Pilotte L. Theate I. Stroobant V. Colau D. Parmentier N. et al. (2003) Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat Med 9: 1269–1274.
    • (2003) Nat Med , vol.9 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Theate, I.3    Stroobant, V.4    Colau, D.5    Parmentier, N.6
  • 245
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • van Cutsem E. Kohne C. Hitre E. Zaluski J. Chang Chien C. Makhson A. et al. (2009) Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 360: 1408–1417.
    • (2009) N Engl J Med , vol.360 , pp. 1408-1417
    • van Cutsem, E.1    Kohne, C.2    Hitre, E.3    Zaluski, J.4    Chang Chien, C.5    Makhson, A.6
  • 246
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
    • van Cutsem E. Peeters M. Siena S. Humblet Y. Hendlisz A. Neyns B. et al. (2007) Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol 25: 1658–1664.
    • (2007) J Clin Oncol , vol.25 , pp. 1658-1664
    • van Cutsem, E.1    Peeters, M.2    Siena, S.3    Humblet, Y.4    Hendlisz, A.5    Neyns, B.6
  • 248
    • 84880755387 scopus 로고    scopus 로고
    • Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results
    • Vansteenkiste J. Zielinski M. Linder A. Dahabreh J. Gonzalez E. Malinowski W. et al. (2013) Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results. J Clin Oncol 31: 2396–2403.
    • (2013) J Clin Oncol , vol.31 , pp. 2396-2403
    • Vansteenkiste, J.1    Zielinski, M.2    Linder, A.3    Dahabreh, J.4    Gonzalez, E.5    Malinowski, W.6
  • 249
    • 84884164729 scopus 로고    scopus 로고
    • CS1, a SLAM family receptor involved in immune regulation, is a therapeutic target in multiple myeloma
    • Veillette A. Guo H. (2013) CS1, a SLAM family receptor involved in immune regulation, is a therapeutic target in multiple myeloma. Crit Rev Oncol Hematol 88: 168–177.
    • (2013) Crit Rev Oncol Hematol , vol.88 , pp. 168-177
    • Veillette, A.1    Guo, H.2
  • 251
    • 34250180582 scopus 로고    scopus 로고
    • Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and / or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
    • Vermorken J. Trigo J. Hitt R. Koralewski P. Diaz-Rubio E. Rolland F. et al. (2007) Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and / or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol 25: 2171–2177.
    • (2007) J Clin Oncol , vol.25 , pp. 2171-2177
    • Vermorken, J.1    Trigo, J.2    Hitt, R.3    Koralewski, P.4    Diaz-Rubio, E.5    Rolland, F.6
  • 253
    • 1142286444 scopus 로고    scopus 로고
    • MUC1 immunobiology: from discovery to clinical applications
    • Vlad A. Kettel J. Alajez N. Carlos C. Finn O. (2004) MUC1 immunobiology: from discovery to clinical applications. Adv Immunol 82: 249–293.
    • (2004) Adv Immunol , vol.82 , pp. 249-293
    • Vlad, A.1    Kettel, J.2    Alajez, N.3    Carlos, C.4    Finn, O.5
  • 255
    • 79952717517 scopus 로고    scopus 로고
    • VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses
    • Wang L. Rubinstein R. Lines J. Wasiuk A. Ahonen C. Guo Y. et al. (2011) VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses. J Exp Med 208: 577–592.
    • (2011) J Exp Med , vol.208 , pp. 577-592
    • Wang, L.1    Rubinstein, R.2    Lines, J.3    Wasiuk, A.4    Ahonen, C.5    Guo, Y.6
  • 256
    • 84879883805 scopus 로고    scopus 로고
    • Clinical significance and biological roles of SPAG 9 overexpression in non-small cell lung cancer
    • Wang Y. Dong Q. Miao Y. Fu L. Lin X. Wang E. (2013) Clinical significance and biological roles of SPAG 9 overexpression in non-small cell lung cancer. Lung Cancer 81: 266–272.
    • (2013) Lung Cancer , vol.81 , pp. 266-272
    • Wang, Y.1    Dong, Q.2    Miao, Y.3    Fu, L.4    Lin, X.5    Wang, E.6
  • 257
    • 84906924095 scopus 로고    scopus 로고
    • Ponatinib: a third-generation inhibitor for the treatment of CML
    • Wehrle J. Pahl H. von Bubnoff N. (2014) Ponatinib: a third-generation inhibitor for the treatment of CML. Recent Results Cancer Res 201: 99–107.
    • (2014) Recent Results Cancer Res , vol.201 , pp. 99-107
    • Wehrle, J.1    Pahl, H.2    von Bubnoff, N.3
  • 258
    • 77951614830 scopus 로고    scopus 로고
    • Monoclonal antibodies: versatile platforms for cancer immunotherapy
    • Weiner L. Surana R. Wang S. (2010) Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat Rev Immunol 10: 317–327.
    • (2010) Nat Rev Immunol , vol.10 , pp. 317-327
    • Weiner, L.1    Surana, R.2    Wang, S.3
  • 259
    • 84891887628 scopus 로고    scopus 로고
    • Cause and consequence of cancer / testis antigen activation in cancer
    • Whitehurst A. (2014) Cause and consequence of cancer / testis antigen activation in cancer. Annu Rev Pharmacol Toxicol 54: 251–272.
    • (2014) Annu Rev Pharmacol Toxicol , vol.54 , pp. 251-272
    • Whitehurst, A.1
  • 260
    • 84908139963 scopus 로고    scopus 로고
    • Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial
    • Wilke H. Muro K. van Cutsem E. Oh S. Bodoky G. Shimada Y. et al. (2014) Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial. Lancet Oncol 15: 1224–1235.
    • (2014) Lancet Oncol , vol.15 , pp. 1224-1235
    • Wilke, H.1    Muro, K.2    van Cutsem, E.3    Oh, S.4    Bodoky, G.5    Shimada, Y.6
  • 261
    • 70350643679 scopus 로고    scopus 로고
    • Identification of an HLA-A*0201-restrictive CTL epitope from MUC 4 for applicable vaccine therapy
    • Wu J. Wei J. Meng K. Chen J. Gao W. Zhang J. et al. (2009) Identification of an HLA-A*0201-restrictive CTL epitope from MUC 4 for applicable vaccine therapy. Immunopharmacol Immunotoxicol 31: 468–476.
    • (2009) Immunopharmacol Immunotoxicol , vol.31 , pp. 468-476
    • Wu, J.1    Wei, J.2    Meng, K.3    Chen, J.4    Gao, W.5    Zhang, J.6
  • 262
    • 84921742575 scopus 로고    scopus 로고
    • Tecemotide: an antigen-specific cancer immunotherapy
    • Wurz G. Kao C. Wolf M. de Gregorio M. (2014) Tecemotide: an antigen-specific cancer immunotherapy. Hum Vaccin Immunother 10: 3383–3393.
    • (2014) Hum Vaccin Immunother , vol.10 , pp. 3383-3393
    • Wurz, G.1    Kao, C.2    Wolf, M.3    de Gregorio, M.4
  • 263
    • 84928420971 scopus 로고    scopus 로고
    • XAGE-1b Cancer / Testis Antigen Is a Potential Target for Immunotherapy in Prostate Cancer
    • Xie C. Wang G. (2015) XAGE-1b Cancer / Testis Antigen Is a Potential Target for Immunotherapy in Prostate Cancer. Urol Int 94: 354–362.
    • (2015) Urol Int , vol.94 , pp. 354-362
    • Xie, C.1    Wang, G.2
  • 264
    • 84892396884 scopus 로고    scopus 로고
    • EGFR T790M mutation as a possible target for immunotherapy; identification of HLA-A*0201-restricted T cell epitopes derived from the EGFR T790M mutation
    • Yamada T. Azuma K. Muta E. Kim J. Sugawara S. Zhang G. et al. (2013) EGFR T790M mutation as a possible target for immunotherapy; identification of HLA-A*0201-restricted T cell epitopes derived from the EGFR T790M mutation. PloS ONE 8: e78389.
    • (2013) PloS ONE , vol.8 , pp. e78389
    • Yamada, T.1    Azuma, K.2    Muta, E.3    Kim, J.4    Sugawara, S.5    Zhang, G.6
  • 265
    • 84859701005 scopus 로고    scopus 로고
    • IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma
    • Yang Z. Grote D. Ziesmer S. Niki T. Hirashima M. Novak A. et al. (2012) IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma. J Clin Invest 122: 1271–1282.
    • (2012) J Clin Invest , vol.122 , pp. 1271-1282
    • Yang, Z.1    Grote, D.2    Ziesmer, S.3    Niki, T.4    Hirashima, M.5    Novak, A.6
  • 266
    • 84942853584 scopus 로고    scopus 로고
    • Boosting Cancer Immunotherapy with Anti-CD137 Antibody Therapy
    • Yonezawa A. Dutt S. Chester C. Kim J. Kohrt H. (2015) Boosting Cancer Immunotherapy with Anti-CD137 Antibody Therapy. Clin Cancer Res 21: 3113–3120.
    • (2015) Clin Cancer Res , vol.21 , pp. 3113-3120
    • Yonezawa, A.1    Dutt, S.2    Chester, C.3    Kim, J.4    Kohrt, H.5
  • 267
    • 84921029675 scopus 로고    scopus 로고
    • Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS
    • Yoshitake Y. Fukuma D. Yuno A. Hirayama M. Nakayama H. Tanaka T. et al. (2015) Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS. Clin Cancer Res 21: 312–321.
    • (2015) Clin Cancer Res , vol.21 , pp. 312-321
    • Yoshitake, Y.1    Fukuma, D.2    Yuno, A.3    Hirayama, M.4    Nakayama, H.5    Tanaka, T.6
  • 268
    • 80054836022 scopus 로고    scopus 로고
    • Serological identification of HSP 105 as a novel non-Hodgkin lymphoma therapeutic target
    • Zappasodi R. Bongarzone I. Ghedini G. Castagnoli L. Cabras A. Messina A. et al. (2011) Serological identification of HSP 105 as a novel non-Hodgkin lymphoma therapeutic target. Blood 118: 4421–4430.
    • (2011) Blood , vol.118 , pp. 4421-4430
    • Zappasodi, R.1    Bongarzone, I.2    Ghedini, G.3    Castagnoli, L.4    Cabras, A.5    Messina, A.6
  • 269
    • 84905124247 scopus 로고    scopus 로고
    • An updated overview of HPV-associated head and neck carcinomas
    • Zaravinos A. (2014) An updated overview of HPV-associated head and neck carcinomas. Oncotarget 5: 3956–3969.
    • (2014) Oncotarget , vol.5 , pp. 3956-3969
    • Zaravinos, A.1
  • 270
    • 84921435079 scopus 로고    scopus 로고
    • Cancer / testis antigen HCA587-derived long peptide vaccine generates potent immunologic responses and antitumor effects in mouse model
    • Zhang L. Chen J. Song X. Wen W. Li Y. Zhang Y. et al. (2013) Cancer / testis antigen HCA587-derived long peptide vaccine generates potent immunologic responses and antitumor effects in mouse model. Oncol Res 21: 193–200.
    • (2013) Oncol Res , vol.21 , pp. 193-200
    • Zhang, L.1    Chen, J.2    Song, X.3    Wen, W.4    Li, Y.5    Zhang, Y.6
  • 271
    • 84906215670 scopus 로고    scopus 로고
    • Overexpression of MAGE-D4 in colorectal cancer is a potentially prognostic biomarker and immunotherapy target
    • Zhang Q. He S. Shen N. Luo B. Fan R. Fu J. et al. (2014) Overexpression of MAGE-D4 in colorectal cancer is a potentially prognostic biomarker and immunotherapy target. Int J Clin Exp Pathol 7: 3918–3927.
    • (2014) Int J Clin Exp Pathol , vol.7 , pp. 3918-3927
    • Zhang, Q.1    He, S.2    Shen, N.3    Luo, B.4    Fan, R.5    Fu, J.6
  • 272
    • 83655193361 scopus 로고    scopus 로고
    • TroVax((R)) vaccine therapy for renal cell carcinoma
    • Zhang R. Bines S. Ruby C. Kaufman H. (2012) TroVax((R)) vaccine therapy for renal cell carcinoma. Immunotherapy 4: 27–42.
    • (2012) Immunotherapy , vol.4 , pp. 27-42
    • Zhang, R.1    Bines, S.2    Ruby, C.3    Kaufman, H.4
  • 273
    • 77951222450 scopus 로고    scopus 로고
    • Expression of tumor-specific antigen MAGE, GAGE and BAGE in ovarian cancer tissues and cell lines
    • Zhang S. Zhou X. Yu H. Yu Y. (2010) Expression of tumor-specific antigen MAGE, GAGE and BAGE in ovarian cancer tissues and cell lines. BMC Cancer 10: 163.
    • (2010) BMC Cancer , vol.10 , pp. 163
    • Zhang, S.1    Zhou, X.2    Yu, H.3    Yu, Y.4
  • 274
    • 49649114788 scopus 로고    scopus 로고
    • A dendritic cell-based tumour vaccine for lung cancer: full-length XAGE-1b protein-pulsed dendritic cells induce specific cytotoxic T lymphocytes in vitro
    • Zhou Q. Guo A. Xu C. An S. Wang Z. Yang S. et al. (2008) A dendritic cell-based tumour vaccine for lung cancer: full-length XAGE-1b protein-pulsed dendritic cells induce specific cytotoxic T lymphocytes in vitro. Clin Exp Immunol 153: 392–400.
    • (2008) Clin Exp Immunol , vol.153 , pp. 392-400
    • Zhou, Q.1    Guo, A.2    Xu, C.3    An, S.4    Wang, Z.5    Yang, S.6
  • 275
    • 30044434075 scopus 로고    scopus 로고
    • The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
    • Zhu C. Anderson A. Schubart A. Xiong H. Imitola J. Khoury S. et al. (2005) The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol 6: 1245–1252.
    • (2005) Nat Immunol , vol.6 , pp. 1245-1252
    • Zhu, C.1    Anderson, A.2    Schubart, A.3    Xiong, H.4    Imitola, J.5    Khoury, S.6
  • 276
    • 84908128916 scopus 로고    scopus 로고
    • Pancreatic cancer counterattack: MUC 4 mediates Fas-independent apoptosis of antigen-specific cytotoxic T lymphocyte
    • Zhu Y. Zhang J. Liang W. Zhu R. Wang B. Miao Y. et al. (2014) Pancreatic cancer counterattack: MUC 4 mediates Fas-independent apoptosis of antigen-specific cytotoxic T lymphocyte. Oncol Rep 31: 1768–1776.
    • (2014) Oncol Rep , vol.31 , pp. 1768-1776
    • Zhu, Y.1    Zhang, J.2    Liang, W.3    Zhu, R.4    Wang, B.5    Miao, Y.6


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