-
1
-
-
0034789572
-
Phase i study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer
-
discussion 58
-
Palmer M, Parker J, Modi S, et al. Phase I study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer. Clin Lung Cancer 2001;3:49-57.discussion 58
-
(2001)
Clin Lung Cancer
, vol.3
, pp. 49-57
-
-
Palmer, M.1
Parker, J.2
Modi, S.3
-
2
-
-
28444431500
-
Concurrent radiotherapy and tumor targeting with 111In-HMFG1-F(ab')2 in patients with MUC1-positive non-small cell lung cancer
-
Garkavij M, Samarzija M, Ewers SB, et al. Concurrent radiotherapy and tumor targeting with 111In-HMFG1-F(ab')2 in patients with MUC1-positive non-small cell lung cancer. Anticancer Res 2005;25:4663-71
-
(2005)
Anticancer Res
, vol.25
, pp. 4663-4671
-
-
Garkavij, M.1
Samarzija, M.2
Ewers, S.B.3
-
3
-
-
27244449289
-
Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer
-
Butts C, Murray N, Maksymiuk A, et al. Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J Clin Oncol 2005;23:6674-81
-
(2005)
J Clin Oncol
, vol.23
, pp. 6674-6681
-
-
Butts, C.1
Murray, N.2
Maksymiuk, A.3
-
4
-
-
80054742888
-
Updated survival analysis in patients with stage IIIB or IV non-small-cell lung cancer receiving BLP25 liposome vaccine (L-BLP25): Phase IIB randomized, multicenter, open-label trial
-
Butts C, Maksymiuk A, Goss G, et al. Updated survival analysis in patients with stage IIIB or IV non-small-cell lung cancer receiving BLP25 liposome vaccine (L-BLP25): Phase IIB randomized, multicenter, open-label trial. J Cancer Res Clin Oncol 2011;137:1337-42
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, pp. 1337-1342
-
-
Butts, C.1
Maksymiuk, A.2
Goss, G.3
-
5
-
-
50349090322
-
A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV Non-small cell lung cancer
-
Ramlau R, Qiox E, Rolski J, et al. A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV Non-small cell lung cancer. J Thorac Oncol 2008;3:735-44
-
(2008)
J Thorac Oncol
, vol.3
, pp. 735-744
-
-
Ramlau, R.1
Qiox, E.2
Rolski, J.3
-
6
-
-
78649235731
-
A multicenter open-label study to assess the safety of a new formulation of BLP25 liposome vaccine in patients with unresectable stage III non-small-cell lung cancer
-
Butts C, Murrauy RN, Smith CJ, et al. A multicenter open-label study to assess the safety of a new formulation of BLP25 liposome vaccine in patients with unresectable stage III non-small-cell lung cancer. Clin Lung Cancer 2010;11:391-5
-
(2010)
Clin Lung Cancer
, vol.11
, pp. 391-395
-
-
Butts, C.1
Murrauy, R.N.2
Smith, C.J.3
-
7
-
-
81255127285
-
Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: A controlled phase 2B trial
-
Quoix E, Ramlau R, Westeel V, et al. Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: A controlled phase 2B trial. Lancet Oncol 2011;12:1125-33
-
(2011)
Lancet Oncol
, vol.12
, pp. 1125-1133
-
-
Quoix, E.1
Ramlau, R.2
Westeel, V.3
-
8
-
-
0032503501
-
Anti-MUC1 class i restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptide
-
Reddish M, MacLean GD, Koganty RR, et al. Anti-MUC1 class I restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptide. Int J Cancer 1998;76:817-23
-
(1998)
Int J Cancer
, vol.76
, pp. 817-823
-
-
Reddish, M.1
MacLean, G.D.2
Koganty, R.R.3
-
9
-
-
0033032313
-
Specificity analysis of sera from breast cancer patients vaccinated with MUC1-KLH plus QS-21
-
Adluri S, Gilewski T, Zhang S, et al. Specificity analysis of sera from breast cancer patients vaccinated with MUC1-KLH plus QS-21. Br J Cancer 1999;79:1806-12
-
(1999)
Br J Cancer
, vol.79
, pp. 1806-1812
-
-
Adluri, S.1
Gilewski, T.2
Zhang, S.3
-
10
-
-
0034071575
-
Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21
-
Gilewski T, Adluri S, Ragupathi G, et al. Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21. Clin Cancer Res 2000;6:1693-701
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1693-1701
-
-
Gilewski, T.1
Adluri, S.2
Ragupathi, G.3
-
11
-
-
0033852076
-
Recombinant vaccinia virus encoding human MUC1 and IL2 as immunotherapy in patients with breast cancer
-
Scholl SM, Balloul JM, Le Goc G, et al. Recombinant vaccinia virus encoding human MUC1 and IL2 as immunotherapy in patients with breast cancer. J Immunother 2000;23:570-80
-
(2000)
J Immunother
, vol.23
, pp. 570-580
-
-
Scholl, S.M.1
Balloul, J.M.2
Le Goc, G.3
-
12
-
-
0037050724
-
Reevaluation of the cellular immune response in breast cancer patients vaccinated with MUC1
-
Musselli C, Ragpathi G, Gilewski T, et al. Reevaluation of the cellular immune response in breast cancer patients vaccinated with MUC1. Int J Cancer 2002;97:660-7
-
(2002)
Int J Cancer
, vol.97
, pp. 660-667
-
-
Musselli, C.1
Ragpathi, G.2
Gilewski, T.3
-
13
-
-
33745126667
-
Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835]
-
Apostolopoulos V, Pietersz GA, Tsibanis A, et al. Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835]. Breast Cancer Res 2006;8:R27
-
(2006)
Breast Cancer Res
, vol.8
-
-
Apostolopoulos, V.1
Pietersz, G.A.2
Tsibanis, A.3
-
14
-
-
77449106552
-
Phase i dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer
-
Pegram MD, Borges VF, Ibrahim N, et al. Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer. Breast Cancer Res 2009;11:R73
-
(2009)
Breast Cancer Res
, vol.11
-
-
Pegram, M.D.1
Borges, V.F.2
Ibrahim, N.3
-
15
-
-
70350780494
-
Tumor burden influences cytotoxic T cell development in metastatic breast cancer patients-a phase I/II study
-
Wright SE, Rewers-Felkins KA, Quinlin IS, et al. Tumor burden influences cytotoxic T cell development in metastatic breast cancer patients-a phase I/II study. Immunol Invest 2009;38:820-38
-
(2009)
Immunol Invest
, vol.38
, pp. 820-838
-
-
Wright, S.E.1
Rewers-Felkins, K.A.2
Quinlin, I.S.3
-
16
-
-
80455144484
-
Randomized phase II trial of letrozole plus anti-MUC1 antibody AS1402 in hormone receptor-positive locally advanced or metastatic breast cancer
-
Ibrahim NK, Yariz KO, Bondarenko I, et al. Randomized phase II trial of letrozole plus anti-MUC1 antibody AS1402 in hormone receptor-positive locally advanced or metastatic breast cancer. Clin Cancer Res 2011;17:6822-30
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6822-6830
-
-
Ibrahim, N.K.1
Yariz, K.O.2
Bondarenko, I.3
-
17
-
-
33745247366
-
Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients
-
Wierecky J, Muller MR, Wirths S, et al. Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients. Cancer Res 2006;66:5910-18
-
(2006)
Cancer Res
, vol.66
, pp. 5910-5918
-
-
Wierecky, J.1
Muller, M.R.2
Wirths, S.3
-
18
-
-
79955630363
-
Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients
-
Rittig SM, Haentschel M, Weimer KJ, et al. Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients. Mol Ther 2011;19:990-9
-
(2011)
Mol Ther
, vol.19
, pp. 990-999
-
-
Rittig, S.M.1
Haentschel, M.2
Weimer, K.J.3
-
19
-
-
79151471986
-
A phase II study of the cancer vaccine TG4010 alone and in combination with cytokines in patients with metastatic renal clear-cell carcinoma: Clinical and immunological findings
-
Oudard S, Rixe O, Beuselinck B, et al. A phase II study of the cancer vaccine TG4010 alone and in combination with cytokines in patients with metastatic renal clear-cell carcinoma: Clinical and immunological findings. Cancer Immunol Immunother 2011;60:261-71
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 261-271
-
-
Oudard, S.1
Rixe, O.2
Beuselinck, B.3
-
20
-
-
4344713204
-
Phase i trial of antigen-specific gene therapy using a recombinant vaccinia virus encoding MUC-1 and IL-2 in MUC-1-positive patients with advanced prostate cancer
-
Pantuck AJ, van Ophoven A, Gitlitz BJ, et al. Phase I trial of antigen-specific gene therapy using a recombinant vaccinia virus encoding MUC-1 and IL-2 in MUC-1-positive patients with advanced prostate cancer. J Immunother 2004;27:240-53
-
(2004)
J Immunother
, vol.27
, pp. 240-253
-
-
Pantuck, A.J.1
Van Ophoven, A.2
Gitlitz, B.J.3
-
21
-
-
33744546327
-
A pilot study of the liposomal MUC1 vaccine BLP25 in prostate specific antigen failures after radical prostatectomy
-
North SA, Graham K, Bodnar D, et al. A pilot study of the liposomal MUC1 vaccine BLP25 in prostate specific antigen failures after radical prostatectomy. J Urol 2006;176:91-5
-
(2006)
J Urol
, vol.176
, pp. 91-5
-
-
North, S.A.1
Graham, K.2
Bodnar, D.3
-
22
-
-
34848896345
-
A polyvalent vaccine for high-risk prostate patients. "Are more antigens better?"
-
Slovin SF, Ragupathi G, Fernandez C, et al. A polyvalent vaccine for high-risk prostate patients: "are more antigens better?". Cancer Immunol Immunother 2007;56:1921-30
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 1921-1930
-
-
Slovin, S.F.1
Ragupathi, G.2
Fernandez, C.3
-
23
-
-
67651173157
-
MVA-MUC1-IL2 vaccine immunotherapy (TG4010) improves PSA doubling time in patients with prostate cancer with biochemical failure
-
Dreicer R, Stadler WM, Ahmann FR, et al. MVA-MUC1-IL2 vaccine immunotherapy (TG4010) improves PSA doubling time in patients with prostate cancer with biochemical failure. Invest New Drugs 2009;27:379-86
-
(2009)
Invest New Drugs
, vol.27
, pp. 379-386
-
-
Dreicer, R.1
Stadler, W.M.2
Ahmann, F.R.3
-
24
-
-
19944433959
-
Phase i study of a MUC1 vaccine composed of different doses of MUC1 peptide with SB-AS2 adjuvant in resected and locally advanced pancreatic cancer
-
Ramanathan RK, Lee KM, McKolanis J, et al. Phase I study of a MUC1 vaccine composed of different doses of MUC1 peptide with SB-AS2 adjuvant in resected and locally advanced pancreatic cancer. Cancer Immunol Immunother 2005;54:254-64
-
(2005)
Cancer Immunol Immunother
, vol.54
, pp. 254-264
-
-
Ramanathan, R.K.1
Lee, K.M.2
McKolanis, J.3
-
25
-
-
23344445706
-
MUC1 peptide vaccination in patients with advanced pancreas or biliary tract cancer
-
Yamamoto K, Ueno T, Kawaoka T, et al. MUC1 peptide vaccination in patients with advanced pancreas or biliary tract cancer. Anticancer Res 2005;25:3575-9
-
(2005)
Anticancer Res
, vol.25
, pp. 3575-3579
-
-
Yamamoto, K.1
Ueno, T.2
Kawaoka, T.3
-
26
-
-
38849160991
-
Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer
-
Kaufman HL, Kim-Schulze S, Manson K, et al. Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer. J Transl Med 2007;5:60
-
(2007)
J Transl Med
, vol.5
, pp. 60
-
-
Kaufman, H.L.1
Kim-Schulze, S.2
Manson, K.3
-
27
-
-
68149088312
-
A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors
-
Lepisto AJ, Moser AJ, Zeh H, et al. A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors. Cancer Ther 2008;6:955-64
-
(2008)
Cancer Ther
, vol.6
, pp. 955-964
-
-
Lepisto, A.J.1
Moser, A.J.2
Zeh, H.3
-
28
-
-
40549097760
-
Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes
-
Kondo H, Hazama S, Kawaoka T, et al. Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes. Anticancer Res 2008;28:379-87
-
(2008)
Anticancer Res
, vol.28
, pp. 379-387
-
-
Kondo, H.1
Hazama, S.2
Kawaoka, T.3
-
29
-
-
32944475905
-
Mannan-MUC1-pulsed dendritic cell immunotherapy: A phase i trial in patients with adenocarcinoma
-
Loveland BE, Zhao A, White S, et al. Mannan-MUC1-pulsed dendritic cell immunotherapy: A phase I trial in patients with adenocarcinoma. Clin Cancer Res 2006;12:869-77
-
(2006)
Clin Cancer Res
, vol.12
, pp. 869-877
-
-
Loveland, B.E.1
Zhao, A.2
White, S.3
-
30
-
-
79151471698
-
Pitfalls of vaccinations with WT1-, Proteinase3- and MUC1-derived peptides in combination with MontanideISA51 and CpG7909
-
Kuball J, de Boer K, Wagner E, et al. Pitfalls of vaccinations with WT1-, Proteinase3- and MUC1-derived peptides in combination with MontanideISA51 and CpG7909. Cancer Immunol Immunother 2011;60:161-71
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 161-171
-
-
Kuball, J.1
De Boer, K.2
Wagner, E.3
-
31
-
-
0030000007
-
A phase i trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma
-
Goydos JS, Elder E, Whiteside TL, et al. A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma. J Surg Res 1996;63:298-304
-
(1996)
J Surg Res
, vol.63
, pp. 298-304
-
-
Goydos, J.S.1
Elder, E.2
Whiteside, T.L.3
-
32
-
-
0031457133
-
Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein
-
Karanikas V, Hwang LA, Pearson J, et al. Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein. J Clin Invest 1997;100:2783-92
-
(1997)
J Clin Invest
, vol.10
, pp. 2783-2792
-
-
Karanikas, V.1
Hwang, L.A.2
Pearson, J.3
-
33
-
-
0034331218
-
Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells
-
Brossart P, Wirths S, Stuhler G, et al. Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells. Blood 2000;96:3102-8
-
(2000)
Blood
, vol.96
, pp. 3102-3108
-
-
Brossart, P.1
Wirths, S.2
Stuhler, G.3
-
34
-
-
0036453668
-
Mucin gene (MUC1) transfected dendritic cells as vaccine: Results of a phase I/II clinical trial
-
Pecher G, Haring A, Kaiser L, et al. Mucin gene (MUC1) transfected dendritic cells as vaccine: Results of a phase I/II clinical trial. Cancer Immunol Immunother 2002;51:669-73
-
(2002)
Cancer Immunol Immunother
, vol.51
, pp. 669-673
-
-
Pecher, G.1
Haring, A.2
Kaiser, L.3
-
35
-
-
1942481506
-
Dendritic cell vaccine immunotherapy of cancer targeting MUC1 mucin
-
Kontani K, Taguchi O, Ozaki Y, et al. Dendritic cell vaccine immunotherapy of cancer targeting MUC1 mucin. Int J Mol Med 2003;12:493-502
-
(2003)
Int J Mol Med
, vol.12
, pp. 493-502
-
-
Kontani, K.1
Taguchi, O.2
Ozaki, Y.3
-
36
-
-
0742324611
-
Phase i immunotherapy with a modified vaccinia virus (MVA) expressing human MUC1 as antigen-specific immunotherapy in patients with MUC1-positive advanced cancer
-
Rochlitz C, Figlin R, Squiban P, et al. Phase I immunotherapy with a modified vaccinia virus (MVA) expressing human MUC1 as antigen-specific immunotherapy in patients with MUC1-positive advanced cancer. J Gene Med 2003;5:690-9
-
(2003)
J Gene Med
, vol.5
, pp. 690-699
-
-
Rochlitz, C.1
Figlin, R.2
Squiban, P.3
-
37
-
-
34547127136
-
Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer
-
Sabbatini PJ, Ragupathi G, Hood C, et al. Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer. Clin Cancer Res 2007;13:4170-7
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4170-4177
-
-
Sabbatini, P.J.1
Ragupathi, G.2
Hood, C.3
-
38
-
-
49649090374
-
Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma
-
Gulley JL, Arlen PM, Tsang KY, et al. Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma. Clin Cancer Res 2008;14:3060-9
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3060-3069
-
-
Gulley, J.L.1
Arlen, P.M.2
Tsang, K.Y.3
-
39
-
-
0027464958
-
Heterogeneity of mucin gene expression in normal and neoplastic tissues
-
Ho SB, Niehans GA, Lyftogt C, et al. Heterogeneity of mucin gene expression in normal and neoplastic tissues. Cancer Res 1993;53:641-51
-
(1993)
Cancer Res
, vol.53
, pp. 641-651
-
-
Ho, S.B.1
Niehans, G.A.2
Lyftogt, C.3
-
40
-
-
18444395585
-
Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl-Lewis(a) and sialyl-Lewis (x) antigens in colorectal adenocarcinoma
-
Baldus SE, Monig SP, Hanisch FG, et al. Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl-Lewis(a) and sialyl-Lewis(x) antigens in colorectal adenocarcinoma. Histopathology 2002;40:440-9
-
(2002)
Histopathology
, vol.40
, pp. 440-449
-
-
Baldus, S.E.1
Monig, S.P.2
Hanisch, F.G.3
-
41
-
-
33750727658
-
MUC1 expression and anti-MUC1 serum immune response in head and neck squamous cell carcinoma (HNSCC): A multivariate analysis
-
Rabassa ME, Croce MV, Pereyra A, et al. MUC1 expression and anti-MUC1 serum immune response in head and neck squamous cell carcinoma (HNSCC): A multivariate analysis. BMC Cancer 2006;6:253
-
(2006)
BMC Cancer
, vol.6
, pp. 253
-
-
Rabassa, M.E.1
Croce, M.V.2
Pereyra, A.3
-
42
-
-
0028235908
-
Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients
-
Kotera Y, Fontenot JD, Pecher G, et al. Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients. Cancer Res 1994;54:2856-60
-
(1994)
Cancer Res
, vol.54
, pp. 2856-2860
-
-
Kotera, Y.1
Fontenot, J.D.2
Pecher, G.3
-
43
-
-
17344392248
-
Survival in early breast cancer patients is favorably influenced by a natural humoral immune response to polymorphic epithelial mucin
-
von Mensdorff-Pouilly S, Vertsraeten AA, Kenemans P, et al. Survival in early breast cancer patients is favorably influenced by a natural humoral immune response to polymorphic epithelial mucin. J Clin Oncol 2000;18:574-83
-
(2000)
J Clin Oncol
, vol.18
, pp. 574-583
-
-
Von Mensdorff-Pouilly, S.1
Vertsraeten, A.A.2
Kenemans, P.3
-
45
-
-
70349265219
-
Humoral immune response to abnormal MUC1 in subjects with colorectal adenoma and cancer
-
Silk AW, Schoen RE, Potter DM, et al. Humoral immune response to abnormal MUC1 in subjects with colorectal adenoma and cancer. Mol Immunol 2009;47:52-6
-
(2009)
Mol Immunol
, vol.47
, pp. 52-6
-
-
Silk, A.W.1
Schoen, R.E.2
Potter, D.M.3
-
46
-
-
77953302327
-
Anti-MUC1 antibodies and ovarian cancer risk: Prospective data from the Nurses' Health Studies
-
Pinheiro SP, Hankinson SE, Tworoger SS, et al. Anti-MUC1 antibodies and ovarian cancer risk: Prospective data from the Nurses' Health Studies. Cancer Epidemiol Biomarkers Prev 2010;19:1595-601
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 1595-1601
-
-
Pinheiro, S.P.1
Hankinson, S.E.2
Tworoger, S.S.3
-
47
-
-
49749121533
-
Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection
-
Varela JC, Atkinson C, Woolson R, et al. Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection. Int J Cancer 2008;123:1357-63
-
(2008)
Int J Cancer
, vol.123
, pp. 1357-1363
-
-
Varela, J.C.1
Atkinson, C.2
Woolson, R.3
-
48
-
-
0024454148
-
Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells
-
Barnd DL, Lan MS, Metzgar RS, et al. Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells. Proc Natl Acad Sci USA 1989;86:7159-63
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7159-7163
-
-
Barnd, D.L.1
Lan, M.S.2
Metzgar, R.S.3
-
49
-
-
70450247207
-
Mucins in cancer: Function, prognosis and therapy
-
Kufe DW. Mucins in cancer: Function, prognosis and therapy. Nat Rev Cancer 2009;9:874-85
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 874-885
-
-
Kufe, D.W.1
-
50
-
-
0030958706
-
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion
-
Yamamoto M, Bharti A, Li Y, et al. Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion. J Biol Chem 1997;272:12492-4
-
(1997)
J Biol Chem
, vol.272
, pp. 12492-12494
-
-
Yamamoto, M.1
Bharti, A.2
Li, Y.3
-
52
-
-
28544448610
-
MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin
-
Huang L, Chen D, Liu D, et al. MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin. Cancer Res 2005;65:0413-22
-
(2005)
Cancer Res
, vol.65
, pp. 0413-0422
-
-
Huang, L.1
Chen, D.2
Liu, D.3
-
53
-
-
0141733054
-
Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin
-
Wen Y, Caffrey TC, Wheelock MJ, et al. Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin. J Biol Chem 2003;278:38029-39
-
(2003)
J Biol Chem
, vol.278
, pp. 38029-38039
-
-
Wen, Y.1
Caffrey, T.C.2
Wheelock, M.J.3
-
54
-
-
79953061206
-
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
-
Roy LD, Sahraei M, Subramani DB, et al. MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition. Oncogene 2011;30:1449-59
-
(2011)
Oncogene
, vol.30
, pp. 1449-1459
-
-
Roy, L.D.1
Sahraei, M.2
Subramani, D.B.3
-
55
-
-
76849109309
-
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer
-
Khodarev N, Ahmand R, Rajabi H, et al. Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. Oncogene 2010;29:920-9
-
(2010)
Oncogene
, vol.29
, pp. 920-929
-
-
Khodarev, N.1
Ahmand, R.2
Rajabi, H.3
-
56
-
-
82755195700
-
MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-kappaB p65 and binding to cytokine promoters: Importance of extracellular domain
-
Cascio S, Zhang L, Finn OJ. MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-kappaB p65 and binding to cytokine promoters: Importance of extracellular domain. J Biol Chem 2011;286:42248-56
-
(2011)
J Biol Chem
, vol.286
, pp. 42248-42256
-
-
Cascio, S.1
Zhang, L.2
Finn, O.J.3
-
57
-
-
70149111064
-
MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor
-
Ahmad R, Raina D, Joshi MD, et al. MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor. Cancer Res 2009;69:7013-21
-
(2009)
Cancer Res
, vol.69
, pp. 7013-7021
-
-
Ahmad, R.1
Raina, D.2
Joshi, M.D.3
-
58
-
-
0026623301
-
Suppression of cellular aggregation by high levels of episialin
-
Ligtenberg MJ, Buijs F, Vos HL, et al. Suppression of cellular aggregation by high levels of episialin. Cancer Res 1992;52:2318-24
-
(1992)
Cancer Res
, vol.52
, pp. 2318-2324
-
-
Ligtenberg, M.J.1
Buijs, F.2
Vos, H.L.3
-
59
-
-
0029937975
-
A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1
-
Wesseling J, van der Valk SW, Hilkens J. A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1. Mol Biol Cell 1996;7:565-77
-
(1996)
Mol Biol Cell
, vol.7
, pp. 565-577
-
-
Wesseling, J.1
Van Der Valk, S.W.2
Hilkens, J.3
-
60
-
-
33846964873
-
Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion
-
Yu LG, Andrews N, Zhao Q, et al. Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion. J Biol Chem 2007;282:773-81
-
(2007)
J Biol Chem
, vol.282
, pp. 773-781
-
-
Yu, L.G.1
Andrews, N.2
Zhao, Q.3
-
61
-
-
79951583142
-
Mucins in the pathogenesis of breast cancer: Implications in diagnosis prognosis and therapy
-
Mukhopadhyay P, Chakraborti S, Ponnusamy MP, et al. Mucins in the pathogenesis of breast cancer: Implications in diagnosis, prognosis and therapy. Biochim Biophys Acta 2011;1815:224-40
-
(2011)
Biochim Biophys Acta
, vol.1815
, pp. 224-240
-
-
Mukhopadhyay, P.1
Chakraborti, S.2
Ponnusamy, M.P.3
-
62
-
-
34047107850
-
CA15-3 and alkaline phosphatase as predictors for breast cancer recurrence: A combined analysis of seven international breast cancer study group trials
-
Keshaviah A, Dellapasqua S, Rotmensz N, et al. CA15-3 and alkaline phosphatase as predictors for breast cancer recurrence: A combined analysis of seven International Breast Cancer Study Group trials. Ann Oncol 2007;18:701-8
-
(2007)
Ann Oncol
, vol.18
, pp. 701-708
-
-
Keshaviah, A.1
Dellapasqua, S.2
Rotmensz, N.3
-
63
-
-
25144504517
-
Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer
-
Rakha EA, Boyce RW, Abd El-Rehim D, et al. Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer. Mol Pathol 2005;18:1295-304
-
(2005)
Mol Pathol
, vol.18
, pp. 1295-1304
-
-
Rakha, E.A.1
Boyce, R.W.2
Abd El-Rehim, D.3
-
64
-
-
15644365913
-
MUC1 (episialin) expression in non-small cell lung cancer is independent of EGFR and c-erbB-2 expression and correlates with poor survival in node positive patients
-
Guddo F, Giatromanolaki A, Koukourakis MI, et al. MUC1 (episialin) expression in non-small cell lung cancer is independent of EGFR and c-erbB-2 expression and correlates with poor survival in node positive patients. J Clin Pathol 1998;51:667-71
-
(1998)
J Clin Pathol
, vol.51
, pp. 667-671
-
-
Guddo, F.1
Giatromanolaki, A.2
Koukourakis, M.I.3
-
65
-
-
15144341821
-
Depolarized expression of episialin (EMA, MUC1) in lung adenocarcinoma is associated with tumor progression
-
Guddo F, Giatromanolaki A, Patriarca C, et al. Depolarized expression of episialin (EMA, MUC1) in lung adenocarcinoma is associated with tumor progression. Anticancer Res 1998;18:1915-20
-
(1998)
Anticancer Res
, vol.18
, pp. 1915-1920
-
-
Guddo, F.1
Giatromanolaki, A.2
Patriarca, C.3
-
66
-
-
0037211750
-
Circulating anti-MUC1 IgG antibodies as a favorable prognostic factor for pancreatic cancer
-
Hamanaka Y, Suehiro Y, Fukui M, et al. Circulating anti-MUC1 IgG antibodies as a favorable prognostic factor for pancreatic cancer. Int J Cancer 2003;103:97-100
-
(2003)
Int J Cancer
, vol.103
, pp. 97-100
-
-
Hamanaka, Y.1
Suehiro, Y.2
Fukui, M.3
-
67
-
-
84860390208
-
Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis
-
Blixt O, Bueti D, Burford B, et al. Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis. Breast Cancer Res 2011;13:R25
-
(2011)
Breast Cancer Res
, Issue.13
-
-
Blixt, O.1
Bueti, D.2
Burford, B.3
-
68
-
-
34247232152
-
Humoral immune response to MUC1 and to the Thomsen-Friedenreich (TF) glycotope in patients with gastric cancer: Relation to survival
-
Kurtenkov O, Klaamas K, Mensdorff-Pouilly S, et al. Humoral immune response to MUC1 and to the Thomsen-Friedenreich (TF) glycotope in patients with gastric cancer: Relation to survival. Acta Oncol 2007;46:316-23
-
(2007)
Acta Oncol
, vol.46
, pp. 316-323
-
-
Kurtenkov, O.1
Klaamas, K.2
Mensdorff-Pouilly, S.3
-
69
-
-
18544377499
-
Conditions associated with antibodies against the tumor-associated antigen MUC1 and their relationship to risk for ovarian cancer
-
Cramer DW, Titus-Ernstoff L, McKolanis J, et al. Conditions associated with antibodies against the tumor-associated antigen MUC1 and their relationship to risk for ovarian cancer. Cancer Epidemiol Biomarkers Prev 2005;14:1125-31
-
(2005)
Cancer Epidemiol Biomarkers Prev
, vol.14
, pp. 1125-1131
-
-
Cramer, D.W.1
Titus-ernstoff, L.2
McKolanis, J.3
-
70
-
-
51949104317
-
Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer
-
Oei AL, Moreno M, Verheijen RH, et al. Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer. Int J Cancer 2008;123:1848-53
-
(2008)
Int J Cancer
, vol.123
, pp. 1848-1853
-
-
Oei, A.L.1
Moreno, M.2
Verheijen, R.H.3
-
71
-
-
79959273645
-
Treatment of advanced pancreatic carcinoma with 90Y-Clivatuzumab Tetraxetan: A phase i single-dose escalation trial
-
Gulec SA, Cohen SJ, Pennington KL, et al. Treatment of advanced pancreatic carcinoma with 90Y-Clivatuzumab Tetraxetan: A phase I single-dose escalation trial. Clin Cancer Res 2011;17:4091-100
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4091-4100
-
-
Gulec, S.A.1
Cohen, S.J.2
Pennington, K.L.3
-
72
-
-
49849084482
-
Adoptive immunotherapy for pancreatic cancer: Cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1
-
Kawaoka T, Oka M, Takashima M, et al. Adoptive immunotherapy for pancreatic cancer: Cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1. Oncol Rep 2008;20:155-63
-
(2008)
Oncol Rep
, vol.20
, pp. 155-163
-
-
Kawaoka, T.1
Oka, M.2
Takashima, M.3
-
73
-
-
84856834217
-
Cytotoxic T-lymphocyte immunotherapy for ovarian cancer: A pilot study
-
Wright SE, Rewers-Felkins KA, Quinlin IS, et al. Cytotoxic T-lymphocyte immunotherapy for ovarian cancer: A pilot study. J Immunother 2012;35:196-204
-
(2012)
J Immunother
, vol.35
, pp. 196-204
-
-
Wright, S.E.1
Rewers-Felkins, K.A.2
Quinlin, I.S.3
-
74
-
-
22944469742
-
Feasibility study of adoptive immunotherapy for metastatic lung tumors using peptide-pulsed dendritic cell-activated killer (PDAK) cells
-
Yamaguchi Y, Ohta K, Kawabuchi Y, et al. Feasibility study of adoptive immunotherapy for metastatic lung tumors using peptide-pulsed dendritic cell-activated killer (PDAK) cells. Anticancer Res 2005;25: 2407-2415
-
(2005)
Anticancer Res
, vol.25
, pp. 2407-2415
-
-
Yamaguchi, Y.1
Ohta, K.2
Kawabuchi, Y.3
-
75
-
-
84862330575
-
Immunotheraphy with IL-10- and IFN-g-Producing CD4 Effector Cells Modulate "natyrac" and "inducible" CD4 TReg cell subpopulation levels: Observations in four cases of patients with ovarian cancer
-
Dobrzanski MJ, Rewers-Felkins KA, Samad KA, et al. Immunotheraphy with IL-10- and IFN-g-Producing CD4 effector cells modulate "Natyrac" and "Inducible" CD4 TReg cell subpopulation levels: Observations in four cases of patients with ovarian cancer. Cancer Immunol Immunother 2012;61(6):839-54
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.6
, pp. 839-854
-
-
Dobrzanski, M.J.1
Rewers-Felkins, K.A.2
Samad, K.A.3
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