-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010; 60(5): 277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, Issue.5
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
2
-
-
67650924582
-
Pancreatic cancer: Molecular pathogenesis and new therapeutic targets
-
Wong HH, Lemoine NR. Pancreatic cancer: molecular pathogenesis and new therapeutic targets. Nature Rev Gastroenterol Hepatol 2009; 6(7): 412-22.
-
(2009)
Nature Rev Gastroenterol Hepatol
, vol.6
, Issue.7
, pp. 412-422
-
-
Wong, H.H.1
Lemoine, N.R.2
-
3
-
-
78650582001
-
Current status of molecular markers for early detection of sporadic pancreatic cancer
-
Chakraborty S, Baine MJ, Sasson AR, Batra SK. Current status of molecular markers for early detection of sporadic pancreatic cancer. Biochim Biophys Acta 2011; 1815(1): 44-64.
-
(2011)
Biochim Biophys Acta
, vol.1815
, Issue.1
, pp. 44-64
-
-
Chakraborty, S.1
Baine, M.J.2
Sasson, A.R.3
Batra, S.K.4
-
4
-
-
55249085150
-
Cancer of the pancreas: Are we making progress? A review of studies in the US Oncology Research Network
-
Cartwright T, Richards DA, Boehm KA. Cancer of the pancreas: are we making progress? A review of studies in the US Oncology Research Network. Cancer Control 2008; 15(4): 308-13.
-
(2008)
Cancer Control
, vol.15
, Issue.4
, pp. 308-313
-
-
Cartwright, T.1
Richards, D.A.2
Boehm, K.A.3
-
5
-
-
18844375044
-
Treatment for pancreatic cancer: Current therapy and continued progress
-
Lockhart AC, Rothenberg ML, Berlin JD. Treatment for pancreatic cancer: current therapy and continued progress. Gastroenterology 2005; 128(6): 1642-54.
-
(2005)
Gastroenterology
, vol.128
, Issue.6
, pp. 1642-1654
-
-
Lockhart, A.C.1
Rothenberg, M.L.2
Berlin, J.D.3
-
6
-
-
61449119672
-
Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer
-
El Maalouf G, Le Tourneau C, Batty GN, Faivre S, Raymond E. Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer. Cancer Treat Rev 2009; 35(2): 167-74.
-
(2009)
Cancer Treat Rev
, vol.35
, Issue.2
, pp. 167-174
-
-
El Maalouf, G.1
Le Tourneau, C.2
Batty, G.N.3
Faivre, S.4
Raymond, E.5
-
7
-
-
0032985541
-
Pancreatic cancer: A report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database
-
Sener SF, Fremgen A, Menck HR, Winchester DP. Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database. J Am Coll Surg 1999; 189(1): 1-7.
-
(1999)
J Am Coll Surg
, vol.189
, Issue.1
, pp. 1-7
-
-
Sener, S.F.1
Fremgen, A.2
Menck, H.R.3
Winchester, D.P.4
-
8
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive KP, Jacobetz MA, Davidson CJ, et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 2009; 324(5933): 1457-61.
-
(2009)
Science
, vol.324
, Issue.5933
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
-
9
-
-
79958171232
-
Stromal biology and therapy in pancreatic cancer
-
In press
-
[Neesse A, Michl P, Frese KK, et al. Stromal biology and therapy in pancreatic cancer. Gut 2010; In press.
-
(2010)
Gut
-
-
Neesse, A.1
Michl, P.2
Frese, K.K.3
-
10
-
-
0035678782
-
Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: A potential role of MUC4 as a tumor marker of diagnostic significance
-
Andrianifahanana M, Moniaux N, Schmied BM, et al. Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance. Clin Cancer Res 2001; 7(12): 4033-40.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.12
, pp. 4033-4040
-
-
Andrianifahanana, M.1
Moniaux, N.2
Schmied, B.M.3
-
11
-
-
0028293812
-
Expression of MUC1, MUC2, MUC3 and MUC4 mucin mRNAs in human pancreatic and intestinal tumor cell lines
-
Hollingsworth MA, Strawhecker JM, Caffrey TC, Mack DR. Expression of MUC1, MUC2, MUC3 and MUC4 mucin mRNAs in human pancreatic and intestinal tumor cell lines. Int J Cancer 1994; 57(2): 198-203.
-
(1994)
Int J Cancer
, vol.57
, Issue.2
, pp. 198-203
-
-
Hollingsworth, M.A.1
Strawhecker, J.M.2
Caffrey, T.C.3
Mack, D.R.4
-
12
-
-
0035892304
-
Overexpression of MUC1 reconfigures the binding properties of tumor cells
-
McDermott KM, Crocker PR, Harris A, et al. Overexpression of MUC1 reconfigures the binding properties of tumor cells. International journal of cancer 2001; 94(6): 783-91.
-
(2001)
International Journal of Cancer
, vol.94
, Issue.6
, pp. 783-791
-
-
McDermott, K.M.1
Crocker, P.R.2
Harris, A.3
-
13
-
-
0036233702
-
MUC4 expression increases progressively in pancreatic intraepithelial neoplasia
-
Swartz MJ, Batra SK, Varshney GC, et al. MUC4 expression increases progressively in pancreatic intraepithelial neoplasia. Am J Clin Pathol 2002; 117(5): 791-6.
-
(2002)
Am J Clin Pathol
, vol.117
, Issue.5
, pp. 791-796
-
-
Swartz, M.J.1
Batra, S.K.2
Varshney, G.C.3
-
14
-
-
70349653064
-
Pancreatic cancer cells resistance to gemcitabine: The role of MUC4 mucin
-
Bafna S, Kaur S, Momi N, Batra SK. Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin. Br J Cancer 2009; 101(7): 1155-61.
-
(2009)
Br J Cancer
, vol.101
, Issue.7
, pp. 1155-1161
-
-
Bafna, S.1
Kaur, S.2
Momi, N.3
Batra, S.K.4
-
15
-
-
57649171078
-
Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours
-
Kalra AV, Campbell RB. Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours. Eur J Cancer 2009; 45(1): 164-73.
-
(2009)
Eur J Cancer
, vol.45
, Issue.1
, pp. 164-173
-
-
Kalra, A.V.1
Campbell, R.B.2
-
16
-
-
77950828177
-
MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies
-
Mimeault M, Johansson SL, Senapati S, Momi N, Chakraborty S, Batra SK. MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies. Cancer Lett 2010; 295(1): 69-84.
-
(2010)
Cancer Lett
, vol.295
, Issue.1
, pp. 69-84
-
-
Mimeault, M.1
Johansson, S.L.2
Senapati, S.3
Momi, N.4
Chakraborty, S.5
Batra, S.K.6
-
17
-
-
73349125438
-
Current status of mucins in the diagnosis and therapy of cancer
-
Rachagani S, Torres MP, Moniaux N, Batra SK. Current status of mucins in the diagnosis and therapy of cancer. Biofactors 2009; 35(6): 509-27.
-
(2009)
Biofactors
, vol.35
, Issue.6
, pp. 509-527
-
-
Rachagani, S.1
Torres, M.P.2
Moniaux, N.3
Batra, S.K.4
-
18
-
-
0033799905
-
Mucins and mucosal protection in the gastrointestinal tract: New prospects for mucins in the pathology of gastrointestinal disease
-
Corfield AP, Myerscough N, Longman R, Sylvester P, Arul S, Pignatelli M. Mucins and mucosal protection in the gastrointestinal tract: new prospects for mucins in the pathology of gastrointestinal disease. Gut 2000; 47(4): 589-94.
-
(2000)
Gut
, vol.47
, Issue.4
, pp. 589-594
-
-
Corfield, A.P.1
Myerscough, N.2
Longman, R.3
Sylvester, P.4
Arul, S.5
Pignatelli, M.6
-
19
-
-
78651460237
-
Role of mucins in the skin during benign and malignant conditions
-
Chakraborty S, Bonthu N, Swanson BJ, Batra SK. Role of mucins in the skin during benign and malignant conditions. Cancer Lett 2011; 301(2): 127-41.
-
(2011)
Cancer Lett
, vol.301
, Issue.2
, pp. 127-141
-
-
Chakraborty, S.1
Bonthu, N.2
Swanson, B.J.3
Batra, S.K.4
-
20
-
-
1242337458
-
Mucins and mucin binding proteins in colorectal cancer
-
Byrd JC, Bresalier RS. Mucins and mucin binding proteins in colorectal cancer. Cancer Metastasis Rev 2004; 23(1-2): 77-99.
-
(2004)
Cancer Metastasis Rev
, vol.23
, Issue.1-2
, pp. 77-99
-
-
Byrd, J.C.1
Bresalier, R.S.2
-
21
-
-
0347123435
-
Mucins in cancer: Protection and control of the cell surface
-
Hollingsworth MA, Swanson BJ. Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer 2004; 4(1): 45-60.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.1
, pp. 45-60
-
-
Hollingsworth, M.A.1
Swanson, B.J.2
-
22
-
-
1242337458
-
Mucins and mucin binding proteins in colorectal cancer
-
Byrd JC, Bresalier RS. Mucins and mucin binding proteins in colorectal cancer. Cancer Metastasis Rev 2004; 23(1-2): 77-99.
-
(2004)
Cancer Metastasis Rev
, vol.23
, Issue.1-2
, pp. 77-99
-
-
Byrd, J.C.1
Bresalier, R.S.2
-
23
-
-
54349122044
-
Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer
-
Singh AP, Senapati S, Ponnusamy MP, et al. Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer. Lancet Oncol 2008; 9(11): 1076-85.
-
(2008)
Lancet Oncol
, vol.9
, Issue.11
, pp. 1076-1085
-
-
Singh, A.P.1
Senapati, S.2
Ponnusamy, M.P.3
-
24
-
-
33846658776
-
Emerging roles of MUC4 in cancer: A novel target for diagnosis and therapy
-
Singh AP, Chaturvedi P, Batra SK. Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy. Cancer Res 2007; 67(2): 433-6.
-
(2007)
Cancer Res
, vol.67
, Issue.2
, pp. 433-436
-
-
Singh, A.P.1
Chaturvedi, P.2
Batra, S.K.3
-
25
-
-
0033527547
-
The structure and assembly of secreted mucins
-
Perez-Vilar J, Hill RL. The structure and assembly of secreted mucins. J Biol Chem 1999; 274(45): 31751-4.
-
(1999)
J Biol Chem
, vol.274
, Issue.45
, pp. 31751-31754
-
-
Perez-Vilar, J.1
Hill, R.L.2
-
26
-
-
77951019810
-
Mucin-interacting proteins: From function to therapeutics
-
Senapati S, Das S, Batra SK. Mucin-interacting proteins: from function to therapeutics. Trends Biochem Sci 2010; 35(4): 236-45.
-
(2010)
Trends Biochem Sci
, vol.35
, Issue.4
, pp. 236-245
-
-
Senapati, S.1
Das, S.2
Batra, S.K.3
-
28
-
-
72149108714
-
The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers
-
Jonckheere N, Van S I. The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers. Biochimie 2010; 92(1): 1-11.
-
(2010)
Biochimie
, vol.92
, Issue.1
, pp. 1-11
-
-
Jonckheere, N.1
Van, S.I.2
-
29
-
-
0042941382
-
Contribution of the MUC1 tandem repeat and cytoplasmic tail to invasive and metastatic properties of a pancreatic cancer cell line
-
Kohlgraf KG, Gawron AJ, Higashi M, et al. Contribution of the MUC1 tandem repeat and cytoplasmic tail to invasive and metastatic properties of a pancreatic cancer cell line. Cancer Res 2003; 63(16): 5011-20.
-
(2003)
Cancer Res
, vol.63
, Issue.16
, pp. 5011-5020
-
-
Kohlgraf, K.G.1
Gawron, A.J.2
Higashi, M.3
-
30
-
-
33744817052
-
RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells
-
Tsutsumida H, Swanson BJ, Singh PK, et al. RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells. Clin Cancer Res 2006; 12(10): 2976-87.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.10
, pp. 2976-2987
-
-
Tsutsumida, H.1
Swanson, B.J.2
Singh, P.K.3
-
31
-
-
34248218177
-
MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins
-
Chaturvedi P, Singh AP, Moniaux N, et al. MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins. Mol Cancer Res 2007; 5(4): 309-20.
-
(2007)
Mol Cancer Res
, vol.5
, Issue.4
, pp. 309-320
-
-
Chaturvedi, P.1
Singh, A.P.2
Moniaux, N.3
-
32
-
-
1642475141
-
Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis
-
Singh AP, Moniaux N, Chauhan SC, Meza JL, Batra SK. Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis. Cancer Res 2004; 64(2): 622-30.
-
(2004)
Cancer Res
, vol.64
, Issue.2
, pp. 622-630
-
-
Singh, A.P.1
Moniaux, N.2
Chauhan, S.C.3
Meza, J.L.4
Batra, S.K.5
-
33
-
-
0038403798
-
Multidrug resistance correlates with overexpression of Muc4 but inversely with P-glycoprotein and multidrug resistance related protein in transfected human melanoma cells
-
Hu YP, Haq B, Carraway KL, Savaraj N, Lampidis TJ. Multidrug resistance correlates with overexpression of Muc4 but inversely with P-glycoprotein and multidrug resistance related protein in transfected human melanoma cells. Biochem Pharmacol 2003; 65(9): 1419-25.
-
(2003)
Biochem Pharmacol
, vol.65
, Issue.9
, pp. 1419-1425
-
-
Hu, Y.P.1
Haq, B.2
Carraway, K.L.3
Savaraj, N.4
Lampidis, T.J.5
-
34
-
-
34347217519
-
MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells
-
Siragusa M, Zerilli M, Iovino F, et al. MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells. Cancer Res 2007; 67(11): 5522-30.
-
(2007)
Cancer Res
, vol.67
, Issue.11
, pp. 5522-5530
-
-
Siragusa, M.1
Zerilli, M.2
Iovino, F.3
-
35
-
-
70349895167
-
MUC1* is a determinant of trastuzumab (Herceptin) resistance in breast cancer cells
-
Fessler SP, Wotkowicz MT, Mahanta SK, Bamdad C. MUC1* is a determinant of trastuzumab (Herceptin) resistance in breast cancer cells. Breast Cancer Res Treat 2009; 118(1): 113-24.
-
(2009)
Breast Cancer Res Treat
, vol.118
, Issue.1
, pp. 113-124
-
-
Fessler, S.P.1
Wotkowicz, M.T.2
Mahanta, S.K.3
Bamdad, C.4
-
36
-
-
20344407571
-
Immunotherapy for pancreatic cancer-science driving clinical progress
-
Laheru D, Jaffee EM. Immunotherapy for pancreatic cancer-science driving clinical progress. Nat Rev Cancer 2005; 5(6): 459-67.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.6
, pp. 459-467
-
-
Laheru, D.1
Jaffee, E.M.2
-
37
-
-
0031963862
-
Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model
-
Rowse GJ, Tempero RM, VanLith ML, Hollingsworth MA, Gendler SJ. Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model. Cancer Res 1998; 58(2): 315-21.
-
(1998)
Cancer Res
, vol.58
, Issue.2
, pp. 315-321
-
-
Rowse, G.J.1
Tempero, R.M.2
Vanlith, M.L.3
Hollingsworth, M.A.4
Gendler, S.J.5
-
38
-
-
0032533812
-
CD4+ lymphocytes provide MUC1-specific tumor immunity in vivo that is undetectable in vitro and is absent in MUC1 transgenic mice
-
Tempero RM, VanLith ML, Morikane K, Rowse GJ, Gendler SJ, Hollingsworth MA. CD4+ lymphocytes provide MUC1-specific tumor immunity in vivo that is undetectable in vitro and is absent in MUC1 transgenic mice. J Immunol 1998; 161(10): 5500-6.
-
(1998)
J Immunol
, vol.161
, Issue.10
, pp. 5500-5506
-
-
Tempero, R.M.1
Vanlith, M.L.2
Morikane, K.3
Rowse, G.J.4
Gendler, S.J.5
Hollingsworth, M.A.6
-
39
-
-
0030000007
-
A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma
-
Goydos JS, Elder E, Whiteside TL, Finn OJ, Lotze MT. A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma. The J Surg Res 1996; 63(1): 298-304.
-
(1996)
The J Surg Res
, vol.63
, Issue.1
, pp. 298-304
-
-
Goydos, J.S.1
Elder, E.2
Whiteside, T.L.3
Finn, O.J.4
Lotze, M.T.5
-
40
-
-
68149088312
-
A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors
-
Lepisto AJ, Moser AJ, Zeh H, et al. A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors. Cancer Ther 2008; 6(B): 955-64.
-
(2008)
Cancer Ther
, vol.6
, Issue.B
, pp. 955-964
-
-
Lepisto, A.J.1
Moser, A.J.2
Zeh, H.3
-
41
-
-
19944433959
-
Phase I study of a MUC1 vaccine composed of different doses of MUC1 peptide with SB-AS2 adjuvant in resected and locally advanced pancreatic cancer
-
Ramanathan RK, Lee KM, McKolanis J, et al. Phase I study of a MUC1 vaccine composed of different doses of MUC1 peptide with SB-AS2 adjuvant in resected and locally advanced pancreatic cancer. Cancer Immunol Immunother 2005; 54(3): 254-64.
-
(2005)
Cancer Immunol Immunother
, vol.54
, Issue.3
, pp. 254-264
-
-
Ramanathan, R.K.1
Lee, K.M.2
McKolanis, J.3
-
42
-
-
1142286444
-
MUC1 immunobiology: From discovery to clinical applications
-
Vlad AM, Kettel JC, Alajez NM, Carlos CA, Finn OJ. MUC1 immunobiology: from discovery to clinical applications. Adv Immunol 2004; 82: 249-93.
-
(2004)
Adv Immunol
, vol.82
, pp. 249-293
-
-
Vlad, A.M.1
Kettel, J.C.2
Alajez, N.M.3
Carlos, C.A.4
Finn, O.J.5
-
43
-
-
23344445706
-
MUC1 peptide vaccination in patients with advanced pancreas or biliary tract cancer
-
Yamamoto K, Ueno T, Kawaoka T, et al. MUC1 peptide vaccination in patients with advanced pancreas or biliary tract cancer. Anticancer Res 2005; 25(5): 3575-9.
-
(2005)
Anticancer Res
, vol.25
, Issue.5
, pp. 3575-3579
-
-
Yamamoto, K.1
Ueno, T.2
Kawaoka, T.3
-
44
-
-
0035339389
-
Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection
-
Soares MM, Mehta V, Finn OJ. Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection. J Immunol 2001; 166(11): 6555-63.
-
(2001)
J Immunol
, vol.166
, Issue.11
, pp. 6555-6563
-
-
Soares, M.M.1
Mehta, V.2
Finn, O.J.3
-
45
-
-
0036453668
-
Mucin gene (MUC1) transfected dendritic cells as vaccine: Results of a phase I/II clinical trial
-
Pecher G, Haring A, Kaiser L, Thiel E. Mucin gene (MUC1) transfected dendritic cells as vaccine: results of a phase I/II clinical trial. Cancer Immunol Immunother 2002; 51(11-12): 669-73.
-
(2002)
Cancer Immunol Immunother
, vol.51
, Issue.11-12
, pp. 669-673
-
-
Pecher, G.1
Haring, A.2
Kaiser, L.3
Thiel, E.4
-
46
-
-
49849084482
-
Adoptive immunotherapy for pancreatic cancer: Cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1
-
Kawaoka T, Oka M, Takashima M, et al. Adoptive immunotherapy for pancreatic cancer: cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1. Oncol Rep 2008; 20(1): 155-63.
-
(2008)
Oncol Rep
, vol.20
, Issue.1
, pp. 155-163
-
-
Kawaoka, T.1
Oka, M.2
Takashima, M.3
-
47
-
-
33645226817
-
[Adoptive immunotherapy using MUC1--specific CTLs for unresectable pancreatic cancer]
-
Kawaoka T, Takashima M, Yamamoto K, Ueno T, Oka M. [Adoptive immunotherapy using MUC1--specific CTLs for unresectable pancreatic cancer]. Nippon Rinsho 2006; 64 Suppl 1: 279-82.
-
(2006)
Nippon Rinsho
, vol.64
, Issue.SUPPL. 1
, pp. 279-282
-
-
Kawaoka, T.1
Takashima, M.2
Yamamoto, K.3
Ueno, T.4
Oka, M.5
-
48
-
-
40549097760
-
Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes
-
Kondo H, Hazama S, Kawaoka T, et al. Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes. Anticancer Res 2008; 28(1B): 379-87.
-
(2008)
Anticancer Res
, vol.28
, Issue.1 B
, pp. 379-387
-
-
Kondo, H.1
Hazama, S.2
Kawaoka, T.3
-
49
-
-
39749146393
-
Dendritic cells expressing a combined PADRE/MUC4-derived polyepitope DNA vaccine induce multiple cytotoxic T-cell responses
-
Wei J, Gao W, Wu J, et al. Dendritic cells expressing a combined PADRE/MUC4-derived polyepitope DNA vaccine induce multiple cytotoxic T-cell responses. Cancer Biother Radiopharm 2008; 23(1): 121-8.
-
(2008)
Cancer Biother Radiopharm
, vol.23
, Issue.1
, pp. 121-128
-
-
Wei, J.1
Gao, W.2
Wu, J.3
-
50
-
-
70350643679
-
Identification of an HLA-A*0201-restrictive CTL epitope from MUC4 for applicable vaccine therapy
-
Wu J, Wei J, Meng K, et al. Identification of an HLA-A*0201-restrictive CTL epitope from MUC4 for applicable vaccine therapy. Immunopharmacol Immunotoxicol 2009; 31(3): 468-76.
-
(2009)
Immunopharmacol Immunotoxicol
, vol.31
, Issue.3
, pp. 468-476
-
-
Wu, J.1
Wei, J.2
Meng, K.3
-
51
-
-
0036719203
-
Pancreatic cancer research: Challenges, opportunities, and recent developments
-
Fernandez-Zapico ME, Kaczynski JA, Urrutia R. Pancreatic cancer research: challenges, opportunities, and recent developments. Curr Opin Gastroenterol 2002; 18(5): 563-7.
-
(2002)
Curr Opin Gastroenterol
, vol.18
, Issue.5
, pp. 563-567
-
-
Fernandez-Zapico, M.E.1
Kaczynski, J.A.2
Urrutia, R.3
-
52
-
-
1942518888
-
Spontaneous and genetically engineered animal models; use in preclinical cancer drug development
-
Hansen K, Khanna C. Spontaneous and genetically engineered animal models; use in preclinical cancer drug development. Eur J Cancer 2004; 40(6): 858-80.
-
(2004)
Eur J Cancer
, vol.40
, Issue.6
, pp. 858-880
-
-
Hansen, K.1
Khanna, C.2
-
53
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
Hingorani SR, Petricoin EF, Maitra A, et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 2003; 4(6): 437-50.
-
(2003)
Cancer Cell
, vol.4
, Issue.6
, pp. 437-450
-
-
Hingorani, S.R.1
Petricoin, E.F.2
Maitra, A.3
-
54
-
-
40749160803
-
Mucin-type O-glycosylation and its potential use in drug and vaccine development
-
Tarp MA, Clausen H. Mucin-type O-glycosylation and its potential use in drug and vaccine development. Biochim Biophys Acta 2008; 1780(3): 546-63.
-
(2008)
Biochim Biophys Acta
, vol.1780
, Issue.3
, pp. 546-563
-
-
Tarp, M.A.1
Clausen, H.2
-
55
-
-
31144451097
-
Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancerspecific anti-MUC1 antibody responses and override tolerance
-
Sorensen AL, Reis CA, Tarp MA, et al. Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancerspecific anti-MUC1 antibody responses and override tolerance. Glycobiology 2006; 16(2): 96-107.
-
(2006)
Glycobiology
, vol.16
, Issue.2
, pp. 96-107
-
-
Sorensen, A.L.1
Reis, C.A.2
Tarp, M.A.3
-
56
-
-
2142758182
-
Synthesis of tumor-associated glycopeptide antigens for the development of tumor-selective vaccines
-
Dziadek S, Kunz H. Synthesis of tumor-associated glycopeptide antigens for the development of tumor-selective vaccines. Chem Rec 2004; 3(6): 308-21.
-
(2004)
Chem Rec
, vol.3
, Issue.6
, pp. 308-321
-
-
Dziadek, S.1
Kunz, H.2
-
57
-
-
27844564286
-
Summary report on the ISOBM TD-4 Workshop: Analysis of 56 monoclonal antibodies against the MUC1 mucin. San Diego, Calif., November 17-23, 1996
-
Price MR, Rye PD, Petrakou E, et al. Summary report on the ISOBM TD-4 Workshop: analysis of 56 monoclonal antibodies against the MUC1 mucin. San Diego, Calif., November 17-23, 1996. Tumour Biol 1998; 19 Suppl 1: 1-20.
-
(1998)
Tumour Biol
, vol.19
, Issue.SUPPL. 1
, pp. 1-20
-
-
Price, M.R.1
Rye, P.D.2
Petrakou, E.3
-
58
-
-
4444313524
-
Binding patterns of DTR-specific antibodies reveal a glycosylationconditioned tumor-specific epitope of the epithelial mucin (MUC1)
-
Karsten U, Serttas N, Paulsen H, Danielczyk A, Goletz S. Binding patterns of DTR-specific antibodies reveal a glycosylationconditioned tumor-specific epitope of the epithelial mucin (MUC1). Glycobiology 2004; 14(8): 681-92.
-
(2004)
Glycobiology
, vol.14
, Issue.8
, pp. 681-692
-
-
Karsten, U.1
Serttas, N.2
Paulsen, H.3
Danielczyk, A.4
Goletz, S.5
-
59
-
-
33746907011
-
PankoMab: A potent new generation anti-tumour MUC1 antibody
-
Danielczyk A, Stahn R, Faulstich D, et al. PankoMab: a potent new generation anti-tumour MUC1 antibody. Cancer Immunol Immunother 2006; 55(11): 1337-47.
-
(2006)
Cancer Immunol Immunother
, vol.55
, Issue.11
, pp. 1337-1347
-
-
Danielczyk, A.1
Stahn, R.2
Faulstich, D.3
-
60
-
-
77954349368
-
Reactivity of a humanized antibody (hPankoMab) towards a tumor-related MUC1 epitope (TA-MUC1) with various human carcinomas
-
Fan XN, Karsten U, Goletz S, Cao Y. Reactivity of a humanized antibody (hPankoMab) towards a tumor-related MUC1 epitope (TA-MUC1) with various human carcinomas. Pathol Res Pract 2010; 206(8): 585-9.
-
(2010)
Pathol Res Pract
, vol.206
, Issue.8
, pp. 585-589
-
-
Fan, X.N.1
Karsten, U.2
Goletz, S.3
Cao, Y.4
-
61
-
-
14244250598
-
A pilot phase 2 study of oregovomab murine monoclonal antibody to CA125 as an immunotherapeutic agent for recurrent ovarian cancer
-
Ehlen TG, Hoskins PJ, Miller D, et al. A pilot phase 2 study of oregovomab murine monoclonal antibody to CA125 as an immunotherapeutic agent for recurrent ovarian cancer. Int J Gynecol Cancer 2005; 15(6): 1023-34.
-
(2005)
Int J Gynecol Cancer
, vol.15
, Issue.6
, pp. 1023-1034
-
-
Ehlen, T.G.1
Hoskins, P.J.2
Miller, D.3
-
62
-
-
0034947607
-
Induction of CA125-specific B and T cell responses in patients injected with MAb-B43.13--evidence for antibody-mediated antigen-processing and presentation of CA125 in vivo
-
Noujaim AA, Schultes BC, Baum RP, Madiyalakan R. Induction of CA125-specific B and T cell responses in patients injected with MAb-B43.13--evidence for antibody-mediated antigen-processing and presentation of CA125 in vivo. Cancer Biother Radiopharm 2001; 16(3): 187-203.
-
(2001)
Cancer Biother Radiopharm
, vol.16
, Issue.3
, pp. 187-203
-
-
Noujaim, A.A.1
Schultes, B.C.2
Baum, R.P.3
Madiyalakan, R.4
-
64
-
-
37449006756
-
Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin
-
Hassan R, Ebel W, Routhier EL, et al. Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin. Cancer Immun 2007; 7: 20.
-
(2007)
Cancer Immun
, vol.7
, pp. 20
-
-
Hassan, R.1
Ebel, W.2
Routhier, E.L.3
-
65
-
-
33750998782
-
Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors
-
Gubbels JA, Belisle J, Onda M, et al. Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors. Mol Cancer 2006; 5(1): 50.
-
(2006)
Mol Cancer
, vol.5
, Issue.1
, pp. 50
-
-
Gubbels, J.A.1
Belisle, J.2
Onda, M.3
-
66
-
-
78650339895
-
Phase I clinical trial of the chimeric anti-mesothelin monoclonal antibody MORAb-009 in patients with mesothelin-expressing cancers
-
Hassan R, Cohen SJ, Phillips M, et al. Phase I clinical trial of the chimeric anti-mesothelin monoclonal antibody MORAb-009 in patients with mesothelin-expressing cancers. Clin Cancer Res 2010; 16(24): 6132-8.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.24
, pp. 6132-6138
-
-
Hassan, R.1
Cohen, S.J.2
Phillips, M.3
-
67
-
-
0037137849
-
Combined gemcitabine and radioimmunotherapy for the treatment of pancreatic cancer
-
Cardillo TM, Blumenthal R, Ying Z, Gold DV. Combined gemcitabine and radioimmunotherapy for the treatment of pancreatic cancer. Int J Cancer 2002; 97(3): 386-92.
-
(2002)
Int J Cancer
, vol.97
, Issue.3
, pp. 386-392
-
-
Cardillo, T.M.1
Blumenthal, R.2
Ying, Z.3
Gold, D.V.4
-
68
-
-
0034800607
-
Therapeutic advantage of (90)yttrium-versus (131)iodine-labeled PAM4 antibody in experimental pancreatic cancer
-
Cardillo TM, Ying Z, Gold DV. Therapeutic advantage of (90)yttrium-versus (131)iodine-labeled PAM4 antibody in experimental pancreatic cancer. Clin Cancer Res 2001; 7(10): 3186-92.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.10
, pp. 3186-3192
-
-
Cardillo, T.M.1
Ying, Z.2
Gold, D.V.3
-
69
-
-
0034975884
-
Localization of pancreatic cancer with radiolabeled monoclonal antibody PAM4
-
Gold DV, Cardillo T, Goldenberg DM, Sharkey RM. Localization of pancreatic cancer with radiolabeled monoclonal antibody PAM4. Crit Rev Oncol Hematol 2001; 39(1-2): 147-54.
-
(2001)
Crit Rev Oncol Hematol
, vol.39
, Issue.1-2
, pp. 147-154
-
-
Gold, D.V.1
Cardillo, T.2
Goldenberg, D.M.3
Sharkey, R.M.4
-
70
-
-
0028281327
-
Characterization of monoclonal antibody PAM4 reactive with a pancreatic cancer mucin
-
Gold DV, Lew K, Maliniak R, Hernandez M, Cardillo T. Characterization of monoclonal antibody PAM4 reactive with a pancreatic cancer mucin. Int J Cancer 1994; 57(2): 204-10.
-
(1994)
Int J Cancer
, vol.57
, Issue.2
, pp. 204-210
-
-
Gold, D.V.1
Lew, K.2
Maliniak, R.3
Hernandez, M.4
Cardillo, T.5
-
71
-
-
79959273645
-
Treatment of advanced pancreatic carcinoma with 90Y-clivatuzumab tetraxetan: A phase I single dose escalation trial
-
In press
-
[Gulec S.A., Cohen SJ, Pennington KL, et al. Treatment of advanced pancreatic carcinoma with 90Y-clivatuzumab tetraxetan: a phase I single dose escalation trial. Clin Cancer Res 2011; In press.
-
(2011)
Clin Cancer Res
-
-
Gulec, S.A.1
Cohen, S.J.2
Pennington, K.L.3
-
72
-
-
0033903713
-
Highdose therapy with 90Yttrium-labeled monoclonal antibody CC49: A phase I trial
-
Tempero M, Leichner P, Baranowska-Kortylewicz J, et al. Highdose therapy with 90Yttrium-labeled monoclonal antibody CC49: a phase I trial. Clin Cancer Res 2000; 6(8): 3095-102.
-
(2000)
Clin Cancer Res
, vol.6
, Issue.8
, pp. 3095-3102
-
-
Tempero, M.1
Leichner, P.2
Baranowska-Kortylewicz, J.3
-
73
-
-
25144510993
-
In vivo and in vitro inhibition of pancreatic cancer growth by targeted alpha therapy using 213Bi-CHX.A-C595
-
Qu CF, Songl YJ, Rizvi SM, et al. In vivo and in vitro inhibition of pancreatic cancer growth by targeted alpha therapy using 213Bi-CHX.A-C595. Cancer Biol Ther 2005; 4(8): 848-53.
-
(2005)
Cancer Biol Ther
, vol.4
, Issue.8
, pp. 848-853
-
-
Qu, C.F.1
Songl, Y.J.2
Rizvi, S.M.3
-
74
-
-
4444366941
-
Targeted alpha therapy for cancer
-
Allen BJ, Raja C, Rizvi S, et al. Targeted alpha therapy for cancer. Phys Med Biol 2004; 49(16): 3703-12.
-
(2004)
Phys Med Biol
, vol.49
, Issue.16
, pp. 3703-3712
-
-
Allen, B.J.1
Raja, C.2
Rizvi, S.3
-
75
-
-
84860482854
-
-
Gene Therapy Clinical Trials Worldwide website, (viewed 5/1/11)
-
Gene Therapy Clinical Trials Worldwide website. J Gene Med http://www.wiley.com/legacy/wileychi/genmed/clinical/. (viewed 5/1/11). 2011.
-
(2011)
J Gene Med
-
-
-
76
-
-
33744817052
-
RNA interference suppression of MUC1 reduces the growth rate and metastatic phe notype of human pancreatic cancer cells
-
Tsutsumida H, Swanson BJ, Singh PK, et al. RNA interference suppression of MUC1 reduces the growth rate and metastatic phe notype of human pancreatic cancer cells. Clin Cancer Res 2006; 12(10): 2976-87.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.10
, pp. 2976-2987
-
-
Tsutsumida, H.1
Swanson, B.J.2
Singh, P.K.3
-
77
-
-
34548381682
-
Down-regulation of MUC1 in cancer cells inhibits cell migration by promoting Ecadherin/ catenin complex formation
-
Yuan Z, Wong S, Borrelli A, Chung MA. Down-regulation of MUC1 in cancer cells inhibits cell migration by promoting Ecadherin/ catenin complex formation. Biochem Biophys Res Commun 2007; 362(3): 740-6.
-
(2007)
Biochem Biophys Res Commun
, vol.362
, Issue.3
, pp. 740-746
-
-
Yuan, Z.1
Wong, S.2
Borrelli, A.3
Chung, M.A.4
-
78
-
-
77952452039
-
RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells
-
Yamazoe S, Tanaka H, Sawada T, et al. RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells. J Exp Clin Cancer Res 2010; 29: 53.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 53
-
-
Yamazoe, S.1
Tanaka, H.2
Sawada, T.3
-
79
-
-
79952016423
-
Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer
-
Hoshi H, Sawada T, Uchida M, et al. Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer. Int J Oncol 2011; 38(3): 619-27.
-
(2011)
Int J Oncol
, vol.38
, Issue.3
, pp. 619-627
-
-
Hoshi, H.1
Sawada, T.2
Uchida, M.3
-
80
-
-
78650624101
-
RNA interference in the clinic: Challenges and future directions
-
Pecot CV, Calin GA, Coleman RL, Lopez-Berestein G, Sood AK. RNA interference in the clinic: challenges and future directions. Nat Rev Cancer 2011; 11(1): 59-67.
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.1
, pp. 59-67
-
-
Pecot, C.V.1
Calin, G.A.2
Coleman, R.L.3
Lopez-Berestein, G.4
Sood, A.K.5
-
81
-
-
0034186366
-
Prodrug activation enzymes in cancer gene therapy
-
Aghi M, Hochberg F, Breakefield XO. Prodrug activation enzymes in cancer gene therapy. J Gene Med 2000; 2(3): 148-64.
-
(2000)
J Gene Med
, vol.2
, Issue.3
, pp. 148-164
-
-
Aghi, M.1
Hochberg, F.2
Breakefield, X.O.3
-
82
-
-
0028889356
-
Breast cancer selective gene expression and therapy mediated by recombinant adenoviruses containing the DF3/MUC1 promoter
-
Chen L, Chen D, Manome Y, Dong Y, Fine HA, Kufe DW. Breast cancer selective gene expression and therapy mediated by recombinant adenoviruses containing the DF3/MUC1 promoter. J Clin Invest 1995; 96(6): 2775-82.
-
(1995)
J Clin Invest
, vol.96
, Issue.6
, pp. 2775-2782
-
-
Chen, L.1
Chen, D.2
Manome, Y.3
Dong, Y.4
Fine, H.A.5
Kufe, D.W.6
-
83
-
-
0028127077
-
Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir
-
Manome Y, Abe M, Hagen MF, Fine HA, Kufe DW. Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir. Cancer Res 1994; 54(20): 5408-13.
-
(1994)
Cancer Res
, vol.54
, Issue.20
, pp. 5408-5413
-
-
Manome, Y.1
Abe, M.2
Hagen, M.F.3
Fine, H.A.4
Kufe, D.W.5
-
84
-
-
0030730794
-
Use of transcriptional regulatory elements of the MUC1 and ERBB2 genes to drive tumour-selective expression of a prodrug activating enzyme
-
Ring CJ, Blouin P, Martin LA, Hurst HC, Lemoine NR. Use of transcriptional regulatory elements of the MUC1 and ERBB2 genes to drive tumour-selective expression of a prodrug activating enzyme. Gene Ther 1997; 4(10): 1045-52.
-
(1997)
Gene Ther
, vol.4
, Issue.10
, pp. 1045-1052
-
-
Ring, C.J.1
Blouin, P.2
Martin, L.A.3
Hurst, H.C.4
Lemoine, N.R.5
-
85
-
-
19744370831
-
Transcriptional tumor-selective promoter targeting of E. coli purine nucleoside phosphorylase for pancreatic cancer suicide gene therapy
-
Deharvengt S, Wack S, Aprahamian M, Hajri A. Transcriptional tumor-selective promoter targeting of E. coli purine nucleoside phosphorylase for pancreatic cancer suicide gene therapy. J Gene Med 2005; 7(5): 672-80.
-
(2005)
J Gene Med
, vol.7
, Issue.5
, pp. 672-680
-
-
Deharvengt, S.1
Wack, S.2
Aprahamian, M.3
Hajri, A.4
-
86
-
-
38849160991
-
Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer
-
Kaufman HL, Kim-Schulze S, Manson K, et al. Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer. J Transl Med 2007; 5: 60.
-
(2007)
J Transl Med
, vol.5
, pp. 60
-
-
Kaufman, H.L.1
Kim-Schulze, S.2
Manson, K.3
-
87
-
-
59849122181
-
The cancer vaccine roller coaster
-
Goldman B, DeFrancesco L. The cancer vaccine roller coaster. Nat Biotechnol 2009; 27(2): 129-39.
-
(2009)
Nat Biotechnol
, vol.27
, Issue.2
, pp. 129-139
-
-
Goldman, B.1
Defrancesco, L.2
-
88
-
-
77952140698
-
Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: Implications for the development of novel cancer therapies
-
Torres MP, Ponnusamy MP, Chakraborty S, et al. Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies. Mol Cancer Ther 2010; 9(5): 1419-31.
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.5
, pp. 1419-1431
-
-
Torres, M.P.1
Ponnusamy, M.P.2
Chakraborty, S.3
-
89
-
-
66449129565
-
Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications
-
Guturu P, Shah V, Urrutia R. Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications. J Gastrointest Cancer 2009; 40(1-2): 1-9.
-
(2009)
J Gastrointest Cancer
, vol.40
, Issue.1-2
, pp. 1-9
-
-
Guturu, P.1
Shah, V.2
Urrutia, R.3
-
90
-
-
51549099068
-
MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma
-
Tinder TL, Subramani DB, Basu GD, et al. MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma. J Immunol 2008; 181(5): 3116-25.
-
(2008)
J Immunol
, vol.181
, Issue.5
, pp. 3116-3125
-
-
Tinder, T.L.1
Subramani, D.B.2
Basu, G.D.3
-
91
-
-
59849121138
-
Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition
-
Mukherjee P, Basu GD, Tinder TL, et al. Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition. J Immunol 2009; 182(1): 216-24.
-
(2009)
J Immunol
, vol.182
, Issue.1
, pp. 216-224
-
-
Mukherjee, P.1
Basu, G.D.2
Tinder, T.L.3
|