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Volumn 83, Issue 2, 2014, Pages 211-218

Meta-analysis of individual patient data from randomized trials of chemotherapy plus cetuximab as first-line treatment for advanced non-small cell lung cancer

Author keywords

Cetuximab; Chemotherapy; First line; Meta analysis; NSCLC; Tumor

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; GEMCITABINE; NAVELBINE; PACLITAXEL;

EID: 84892844284     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2013.11.006     Document Type: Article
Times cited : (68)

References (39)
  • 2
    • 0035991333 scopus 로고    scopus 로고
    • Prospective population-based study on the survival of patients with lung cancer
    • Makitaro R., Paakko P., Huhti E., Bloigu R., Kinnula V.L. Prospective population-based study on the survival of patients with lung cancer. Eur Respir J 2002, 19:1087-1092.
    • (2002) Eur Respir J , vol.19 , pp. 1087-1092
    • Makitaro, R.1    Paakko, P.2    Huhti, E.3    Bloigu, R.4    Kinnula, V.L.5
  • 3
    • 4344670233 scopus 로고    scopus 로고
    • Population variations in the initial treatment of non-small-cell lung cancer
    • Potosky A.L., Saxman S., Wallace R.B., Lynch C.F. Population variations in the initial treatment of non-small-cell lung cancer. J Clin Oncol 2004, 22:3261-3268.
    • (2004) J Clin Oncol , vol.22 , pp. 3261-3268
    • Potosky, A.L.1    Saxman, S.2    Wallace, R.B.3    Lynch, C.F.4
  • 4
    • 52049090365 scopus 로고    scopus 로고
    • Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
    • Zhu C.Q., da Cunha Santos G., Ding K., Sakurada A., Cutz J.C., Liu N., et al. Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 2008, 26:4268-4275.
    • (2008) J Clin Oncol , vol.26 , pp. 4268-4275
    • Zhu, C.Q.1    da Cunha Santos, G.2    Ding, K.3    Sakurada, A.4    Cutz, J.C.5    Liu, N.6
  • 5
    • 42049101034 scopus 로고    scopus 로고
    • Systemic treatment for advanced (stage IIIb/IV) non-small cell lung cancer: more treatment options; more things to consider. Conclusion
    • Bunn P.A., Thatcher N. Systemic treatment for advanced (stage IIIb/IV) non-small cell lung cancer: more treatment options; more things to consider. Conclusion. Oncologist 2008, 13(Suppl. 1):37-46.
    • (2008) Oncologist , vol.13 , Issue.SUPPL. 1 , pp. 37-46
    • Bunn, P.A.1    Thatcher, N.2
  • 6
    • 42049099094 scopus 로고    scopus 로고
    • Systemic chemotherapy for advanced non-small cell lung cancer: recent advances and future directions
    • Ramalingam S., Belani C. Systemic chemotherapy for advanced non-small cell lung cancer: recent advances and future directions. Oncologist 2008, 13(Suppl. 1):5-13.
    • (2008) Oncologist , vol.13 , Issue.SUPPL. 1 , pp. 5-13
    • Ramalingam, S.1    Belani, C.2
  • 8
    • 77953541527 scopus 로고    scopus 로고
    • Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study
    • Cappuzzo F., Ciuleanu T., Stelmakh L., Cicenas S., Szczesna A., Juhasz E., et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol 2010, 11:521-529.
    • (2010) Lancet Oncol , vol.11 , pp. 521-529
    • Cappuzzo, F.1    Ciuleanu, T.2    Stelmakh, L.3    Cicenas, S.4    Szczesna, A.5    Juhasz, E.6
  • 9
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
    • Rosell R., Carcereny E., Gervais R., Vergnenegre A., Massuti B., Felip E., et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012, 13:239-246.
    • (2012) Lancet Oncol , vol.13 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3    Vergnenegre, A.4    Massuti, B.5    Felip, E.6
  • 10
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A., Gray R., Perry M.C., Brahmer J., Schiller J.H., Dowlati A., et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006, 355:2542-2550.
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3    Brahmer, J.4    Schiller, J.H.5    Dowlati, A.6
  • 11
    • 84871538217 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of randomised, phase II/III trials adding bevacizumab to platinum-based chemotherapy as first-line treatment in patients with advanced non-small-cell lung cancer
    • Soria J.C., Mauguen A., Reck M., Sandler A.B., Saijo N., Johnson D.H., et al. Systematic review and meta-analysis of randomised, phase II/III trials adding bevacizumab to platinum-based chemotherapy as first-line treatment in patients with advanced non-small-cell lung cancer. Ann Oncol 2013, 24:20-30.
    • (2013) Ann Oncol , vol.24 , pp. 20-30
    • Soria, J.C.1    Mauguen, A.2    Reck, M.3    Sandler, A.B.4    Saijo, N.5    Johnson, D.H.6
  • 12
    • 74949133978 scopus 로고    scopus 로고
    • American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer
    • Azzoli C.G., Baker S., Temin S., Pao W., Aliff T., Brahmer J., et al. American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol 2009, 27:6251-6266.
    • (2009) J Clin Oncol , vol.27 , pp. 6251-6266
    • Azzoli, C.G.1    Baker, S.2    Temin, S.3    Pao, W.4    Aliff, T.5    Brahmer, J.6
  • 13
    • 0037106514 scopus 로고    scopus 로고
    • Chemotherapy for advanced non-small-cell lung cancer: who, what, when, why?
    • Bunn P.A. Chemotherapy for advanced non-small-cell lung cancer: who, what, when, why?. J Clin Oncol 2002, 20:23S-33S.
    • (2002) J Clin Oncol , vol.20
    • Bunn, P.A.1
  • 14
    • 66549109768 scopus 로고    scopus 로고
    • Non-small-cell lung cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up
    • D'Addario G., Felip E. Non-small-cell lung cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 2009, 20(Suppl. 4):68-70.
    • (2009) Ann Oncol , vol.20 , Issue.SUPPL. 4 , pp. 68-70
    • D'Addario, G.1    Felip, E.2
  • 15
    • 66349133435 scopus 로고    scopus 로고
    • Impact of third-generation drugs on the activity of first-line chemotherapy in advanced non-small cell lung cancer: a meta-analytical approach
    • Grossi F., Aita M., Defferrari C., Rosetti F., Brianti A., Fasola G., et al. Impact of third-generation drugs on the activity of first-line chemotherapy in advanced non-small cell lung cancer: a meta-analytical approach. Oncologist 2009, 14:497-510.
    • (2009) Oncologist , vol.14 , pp. 497-510
    • Grossi, F.1    Aita, M.2    Defferrari, C.3    Rosetti, F.4    Brianti, A.5    Fasola, G.6
  • 16
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
    • Scagliotti G.V., Parikh P., von Pawel J., Biesma B., Vansteenkiste J., Manegold C., et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 2008, 26:3543-3551.
    • (2008) J Clin Oncol , vol.26 , pp. 3543-3551
    • Scagliotti, G.V.1    Parikh, P.2    von Pawel, J.3    Biesma, B.4    Vansteenkiste, J.5    Manegold, C.6
  • 17
    • 3242803674 scopus 로고    scopus 로고
    • Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: a meta-analysis
    • Delbaldo C., Michiels S., Syz N., Soria J.C., Le Chevalier T., Pignon J.P. Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: a meta-analysis. J Am Med Assoc 2004, 292:470-484.
    • (2004) J Am Med Assoc , vol.292 , pp. 470-484
    • Delbaldo, C.1    Michiels, S.2    Syz, N.3    Soria, J.C.4    Le Chevalier, T.5    Pignon, J.P.6
  • 18
    • 65349116059 scopus 로고    scopus 로고
    • Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial
    • Pirker R., Pereira J.R., Szczesna A., von Pawel J., Krzakowski M., Ramlau R., et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet 2009, 373:1525-1531.
    • (2009) Lancet , vol.373 , pp. 1525-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3    von Pawel, J.4    Krzakowski, M.5    Ramlau, R.6
  • 19
    • 77949891126 scopus 로고    scopus 로고
    • Cetuximab and first-line taxane/carboplatin chemotherapy in advanced non-small-cell lung cancer: results of the randomized multicenter phase III trial BMS099
    • Lynch T.J., Patel T., Dreisbach L., McCleod M., Heim W.J., Hermann R.C., et al. Cetuximab and first-line taxane/carboplatin chemotherapy in advanced non-small-cell lung cancer: results of the randomized multicenter phase III trial BMS099. J Clin Oncol 2010, 28:911-917.
    • (2010) J Clin Oncol , vol.28 , pp. 911-917
    • Lynch, T.J.1    Patel, T.2    Dreisbach, L.3    McCleod, M.4    Heim, W.J.5    Hermann, R.C.6
  • 20
    • 0036167948 scopus 로고    scopus 로고
    • To IPD or not to IPD? Advantages and disadvantages of systematic reviews using individual patient data
    • Stewart L.A., Tierney J.F. To IPD or not to IPD? Advantages and disadvantages of systematic reviews using individual patient data. Eval Health Prof 2002, 25:76-97.
    • (2002) Eval Health Prof , vol.25 , pp. 76-97
    • Stewart, L.A.1    Tierney, J.F.2
  • 21
    • 67349273840 scopus 로고    scopus 로고
    • Role of meta-analyses and of large randomized trials in the study of cancer treatments
    • Pignon J.P., Auperin A., Borget I., Hill C. Role of meta-analyses and of large randomized trials in the study of cancer treatments. Lung Cancer 2009, 65:9-12.
    • (2009) Lung Cancer , vol.65 , pp. 9-12
    • Pignon, J.P.1    Auperin, A.2    Borget, I.3    Hill, C.4
  • 22
    • 37649022615 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine plus cisplatin or carboplatin, with or without cetuximab, as first-line therapy for patients with advanced or metastatic non-small-cell lung cancer
    • Butts C.A., Bodkin D., Middleman E.L., Englund C.W., Ellison D., Alam Y., et al. Randomized phase II study of gemcitabine plus cisplatin or carboplatin, with or without cetuximab, as first-line therapy for patients with advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2007, 25:5777-5784.
    • (2007) J Clin Oncol , vol.25 , pp. 5777-5784
    • Butts, C.A.1    Bodkin, D.2    Middleman, E.L.3    Englund, C.W.4    Ellison, D.5    Alam, Y.6
  • 23
    • 38849114239 scopus 로고    scopus 로고
    • Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small-cell lung cancer
    • Rosell R., Robinet G., Szczesna A., Ramlau R., Constenla M., Mennecier B.C., et al. Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small-cell lung cancer. Ann Oncol 2008, 19:362-369.
    • (2008) Ann Oncol , vol.19 , pp. 362-369
    • Rosell, R.1    Robinet, G.2    Szczesna, A.3    Ramlau, R.4    Constenla, M.5    Mennecier, B.C.6
  • 24
    • 15944393532 scopus 로고    scopus 로고
    • Wiley-Liss, New York, L.H. Sobin, C. Wittekind (Eds.)
    • TNM Classification of Malignant Tumours 2002, 99-103. Wiley-Liss, New York. 6th ed. L.H. Sobin, C. Wittekind (Eds.).
    • (2002) TNM Classification of Malignant Tumours , pp. 99-103
  • 26
    • 77955637020 scopus 로고    scopus 로고
    • Chemotherapy with cetuximab or chemotherapy alone for untreated advanced non-small-cell lung cancer: a systematic review and meta-analysis
    • Lin H., Jiang J., Liang X., Zhou X., Huang R. Chemotherapy with cetuximab or chemotherapy alone for untreated advanced non-small-cell lung cancer: a systematic review and meta-analysis. Lung Cancer 2010, 70:57-62.
    • (2010) Lung Cancer , vol.70 , pp. 57-62
    • Lin, H.1    Jiang, J.2    Liang, X.3    Zhou, X.4    Huang, R.5
  • 27
    • 79954435125 scopus 로고    scopus 로고
    • EGFR-targeted therapies combined with chemotherapy for treating advanced non-small-cell lung cancer: a meta-analysis
    • Chen P., Wang L., Liu B., Zhang H.Z., Liu H.C., Zou Z. EGFR-targeted therapies combined with chemotherapy for treating advanced non-small-cell lung cancer: a meta-analysis. Eur J Clin Pharmacol 2011, 67:235-243.
    • (2011) Eur J Clin Pharmacol , vol.67 , pp. 235-243
    • Chen, P.1    Wang, L.2    Liu, B.3    Zhang, H.Z.4    Liu, H.C.5    Zou, Z.6
  • 28
    • 79959913631 scopus 로고    scopus 로고
    • Cetuximab-based Therapy is effective in chemotherapy-naive patients with advanced and metastatic non-small-cell lung cancer: a meta-analysis of randomized controlled trials
    • Ibrahim E.M., Abouelkhair K.M., Al-Masri O.A., Chaudry N.C., Kazkaz G.A. Cetuximab-based Therapy is effective in chemotherapy-naive patients with advanced and metastatic non-small-cell lung cancer: a meta-analysis of randomized controlled trials. Lung 2011, 189:193-198.
    • (2011) Lung , vol.189 , pp. 193-198
    • Ibrahim, E.M.1    Abouelkhair, K.M.2    Al-Masri, O.A.3    Chaudry, N.C.4    Kazkaz, G.A.5
  • 29
    • 84892861609 scopus 로고    scopus 로고
    • 2013. http://newsroom.lilly.com/releasedetail.cfm%3FReleaseID=784772.
    • (2013)
  • 30
    • 84892839579 scopus 로고    scopus 로고
    • Randomized phase-3 trial (INSPIRE) of necitumumab plus cisplatin-pemetrexed versus cisplatin-pemetrexed alone as first-line therapy in stage IV non-squamous NSCLC
    • [abstract O03.02]
    • Paz-Ares L., Mezger J., Ciuleanu T., Fischer J.R., Von Pawel J., Provencio M., et al. Randomized phase-3 trial (INSPIRE) of necitumumab plus cisplatin-pemetrexed versus cisplatin-pemetrexed alone as first-line therapy in stage IV non-squamous NSCLC. 15th World Conference on Lung Cancer, October 27-31 2013, [abstract O03.02].
    • (2013) 15th World Conference on Lung Cancer, October 27-31
    • Paz-Ares, L.1    Mezger, J.2    Ciuleanu, T.3    Fischer, J.R.4    Von Pawel, J.5    Provencio, M.6
  • 31
    • 84855311144 scopus 로고    scopus 로고
    • EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study
    • Pirker R., Pereira J.R., von Pawel J., Krzakowski M., Ramlau R., Park K., et al. EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study. Lancet Oncol 2012, 13:33-42.
    • (2012) Lancet Oncol , vol.13 , pp. 33-42
    • Pirker, R.1    Pereira, J.R.2    von Pawel, J.3    Krzakowski, M.4    Ramlau, R.5    Park, K.6
  • 32
    • 33744472217 scopus 로고    scopus 로고
    • Significance of EGFR protein expression and gene amplification in non-small cell lung carcinoma
    • Dacic S., Flanagan M., Cieply K., Ramalingam S., Luketich J., Belani C., et al. Significance of EGFR protein expression and gene amplification in non-small cell lung carcinoma. Am J Clin Pathol 2006, 125:860-865.
    • (2006) Am J Clin Pathol , vol.125 , pp. 860-865
    • Dacic, S.1    Flanagan, M.2    Cieply, K.3    Ramalingam, S.4    Luketich, J.5    Belani, C.6
  • 33
    • 0028937815 scopus 로고
    • Epidermal growth factor receptor (EGFR) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype
    • Fontanini G., Vignati S., Bigini D., Mussi A., Lucchi H., Angeletti C.A., et al. Epidermal growth factor receptor (EGFR) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype. Eur J Cancer 1995, 31A:178-183.
    • (1995) Eur J Cancer , vol.31 A , pp. 178-183
    • Fontanini, G.1    Vignati, S.2    Bigini, D.3    Mussi, A.4    Lucchi, H.5    Angeletti, C.A.6
  • 34
    • 0142119289 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis
    • Hirsch F.R., Varella-Garcia M., Bunn P.A., Di Maria M.V., Veve R., Bremmes R.M., et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003, 21:3798-3807.
    • (2003) J Clin Oncol , vol.21 , pp. 3798-3807
    • Hirsch, F.R.1    Varella-Garcia, M.2    Bunn, P.A.3    Di Maria, M.V.4    Veve, R.5    Bremmes, R.M.6
  • 35
    • 18744434862 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression
    • Ohsaki Y., Tanno S., Fujita Y., Toyoshima E., Fujiuchi S., Nishigaki Y., et al. Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression. Oncol Rep 2000, 7:603-607.
    • (2000) Oncol Rep , vol.7 , pp. 603-607
    • Ohsaki, Y.1    Tanno, S.2    Fujita, Y.3    Toyoshima, E.4    Fujiuchi, S.5    Nishigaki, Y.6
  • 36
    • 3843116718 scopus 로고    scopus 로고
    • Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib ('Iressa', ZD1839) in non-small-cell lung cancer
    • Parra H.S., Cavina R., Latteri F., Zucali P.A., Campagnoli E., Morenghi E., et al. Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib ('Iressa', ZD1839) in non-small-cell lung cancer. Br J Cancer 2004, 91:208-212.
    • (2004) Br J Cancer , vol.91 , pp. 208-212
    • Parra, H.S.1    Cavina, R.2    Latteri, F.3    Zucali, P.A.4    Campagnoli, E.5    Morenghi, E.6
  • 37
    • 0023261096 scopus 로고
    • Epidermal growth factor receptors in non-small cell lung cancer
    • Veale D., Ashcroft T., Marsh C., Gibson G.J., Harris A.L. Epidermal growth factor receptors in non-small cell lung cancer. Br J Cancer 1987, 55:513-516.
    • (1987) Br J Cancer , vol.55 , pp. 513-516
    • Veale, D.1    Ashcroft, T.2    Marsh, C.3    Gibson, G.J.4    Harris, A.L.5
  • 38
    • 82655170490 scopus 로고    scopus 로고
    • Incidence and risk of severe neutropenia in advanced cancer patients treated with cetuximab: a meta-analysis
    • Wang L., Chen Y.Z., Shi D., Shi X.Y., Zou Z., Zhao J.H. Incidence and risk of severe neutropenia in advanced cancer patients treated with cetuximab: a meta-analysis. Drugs Res Dev 2011, 11:317-326.
    • (2011) Drugs Res Dev , vol.11 , pp. 317-326
    • Wang, L.1    Chen, Y.Z.2    Shi, D.3    Shi, X.Y.4    Zou, Z.5    Zhao, J.H.6
  • 39
    • 84864489915 scopus 로고    scopus 로고
    • Design of a phase III clinical trial with prospective biomarker validation: SWOG S0819
    • Redman M.W., Crowley J.J., Herbst R.S., Hirsch F.R., Gandara D.R. Design of a phase III clinical trial with prospective biomarker validation: SWOG S0819. Clin Cancer Res 2012, 18:4004-4012.
    • (2012) Clin Cancer Res , vol.18 , pp. 4004-4012
    • Redman, M.W.1    Crowley, J.J.2    Herbst, R.S.3    Hirsch, F.R.4    Gandara, D.R.5


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