-
1
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012;366:2455-65.
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
2
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
3
-
-
85083599525
-
-
Press release: FDA approves Keytruda for advanced melanoma. 2014. Available online:
-
Press release: FDA approves Keytruda for advanced melanoma. 2014. Available online: www.fda.gov/
-
-
-
-
4
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
Topalian SL, Sznol M, McDermott DF, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol 2014;32:1020-30.
-
(2014)
J Clin Oncol
, vol.32
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
-
5
-
-
85083596426
-
Clinical activity, safety and biomarkers of PDL1 blockade in non-small cell lung cancer (NSCLC): Additional analyses from a clinical study of the engineered antibody MPDL3280A (anti-PDL1).
-
European Cancer Congress
-
Novello S. Clinical activity, safety and biomarkers of PDL1 blockade in non-small cell lung cancer (NSCLC): Additional analyses from a clinical study of the engineered antibody MPDL3280A (anti-PDL1). European Cancer Congress 2013:abstr 3408.
-
(2013)
, pp. 3408
-
-
Novello, S.1
-
6
-
-
84908354848
-
Anti-programmeddeath- receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
-
Robert C, Ribas A, Wolchok JD, et al. Anti-programmeddeath- receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 2014;384:1109-17.
-
(2014)
Lancet
, vol.384
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
-
7
-
-
84907521154
-
Preliminary data from a multi-arm expansion study of MEDI4736, an anti- PD-L1 antibody
-
Segal NH, Antonia SJ, Brahmer JR, et al. Preliminary data from a multi-arm expansion study of MEDI4736, an anti- PD-L1 antibody. J Clin Oncol 2014;32:abstr 3002.
-
(2014)
J Clin Oncol
, vol.32
-
-
Segal, N.H.1
Antonia, S.J.2
Brahmer, J.R.3
-
8
-
-
84907532904
-
A Phase 1 Study of MEDI4736, an anti-PD-L1 Antibody, in Patients With Advanced Solid Tumors
-
Lutzky J, Antonia SJ, Blake-Haskins A, et al. A Phase 1 Study of MEDI4736, an anti-PD-L1 Antibody, in Patients With Advanced Solid Tumors. J Clin Oncol 2014;32:abstr 3001.
-
(2014)
J Clin Oncol
, vol.32
-
-
Lutzky, J.1
Antonia, S.J.2
Blake-Haskins, A.3
-
9
-
-
85083611031
-
Clinical activity and safety of MEDI4736, an anti-PD-L1 antibody, in patients with head and neck cancer.
-
2014 European Society of Medical Oncology (ESMO) Meeting, Madrid, Spain:abstr 988PD.
-
Fury M, Bulter M, Ou SH, et al. Clinical activity and safety of MEDI4736, an anti-PD-L1 antibody, in patients with head and neck cancer. 2014 European Society of Medical Oncology (ESMO) Meeting, Madrid, Spain:abstr 988PD.
-
-
-
Fury, M.1
Bulter, M.2
Ou, S.H.3
-
10
-
-
84856867834
-
Immunotherapy earns its spot in the ranks of cancer therapy
-
Pardoll D, Drake C. Immunotherapy earns its spot in the ranks of cancer therapy. J Exp Med 2012;209:201-9.
-
(2012)
J Exp Med
, vol.209
, pp. 201-209
-
-
Pardoll, D.1
Drake, C.2
-
11
-
-
84907609227
-
Pharmacokinetics of MEDI4736, a fully human anti-PDL1 monoclonal antibody, in patients with advanced solid tumors
-
Fairman D, Narwal R, Liang M, et al. Pharmacokinetics of MEDI4736, a fully human anti-PDL1 monoclonal antibody, in patients with advanced solid tumors. J Clin Oncol 2014;32:abstr 2602.
-
(2014)
J Clin Oncol
, vol.32
-
-
Fairman, D.1
Narwal, R.2
Liang, M.3
-
12
-
-
84255197842
-
Cancer immunotherapy comes of age
-
Mellman I, Coukos G, Dranoff G. Cancer immunotherapy comes of age. Nature 2011;480:480-9.
-
(2011)
Nature
, vol.480
, pp. 480-489
-
-
Mellman, I.1
Coukos, G.2
Dranoff, G.3
-
13
-
-
84871192340
-
Molecular pathways: nextgeneration immunotherapy--inhibiting programmed death-ligand 1 and programmed death-1
-
Chen DS, Irving BA, Hodi FS. Molecular pathways: nextgeneration immunotherapy--inhibiting programmed death-ligand 1 and programmed death-1. Clin Cancer Res 2012;18:6580-7.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 6580-6587
-
-
Chen, D.S.1
Irving, B.A.2
Hodi, F.S.3
-
14
-
-
84861064002
-
Programmed death ligand 2 in cancer-induced immune suppression
-
Rozali EN, Hato SV, Robinson BW, et al. Programmed death ligand 2 in cancer-induced immune suppression. Clin Dev Immunol 2012;2012:656340.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 656340
-
-
Rozali, E.N.1
Hato, S.V.2
Robinson, B.W.3
|