-
1
-
-
4644318828
-
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
-
Appelhoff R.J., Tian Y.-M., Raval R.R., Turley H., Harris A.L., Pugh C.W., Ratcliffe P.J., Gleadle J.M. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. J. Biol. Chem. 2004, 279:38458-38465.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 38458-38465
-
-
Appelhoff, R.J.1
Tian, Y.-M.2
Raval, R.R.3
Turley, H.4
Harris, A.L.5
Pugh, C.W.6
Ratcliffe, P.J.7
Gleadle, J.M.8
-
2
-
-
55249095393
-
Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α
-
Ben-Shoshan J., Maysel-Auslender S., Mor A., Keren G., George J. Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α. Eur. J. Immunol. 2008, 38:2412-2418.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 2412-2418
-
-
Ben-Shoshan, J.1
Maysel-Auslender, S.2
Mor, A.3
Keren, G.4
George, J.5
-
3
-
-
1642581653
-
Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1α
-
Blouin C.C., Pagé E.L., Soucy G.M., Richard D.E. Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1α. Blood 2004, 103:1124-1130.
-
(2004)
Blood
, vol.103
, pp. 1124-1130
-
-
Blouin, C.C.1
Pagé, E.L.2
Soucy, G.M.3
Richard, D.E.4
-
4
-
-
84904982108
-
HIF-1α- and hypoxia-dependent immune responses in human CD4+CD2 5high T cells and T helper 17 cells
-
Bollinger T., Gies S., Naujoks J., Feldhoff L., Bollinger A., Solbach W., Rupp J. HIF-1α- and hypoxia-dependent immune responses in human CD4+CD2 5high T cells and T helper 17 cells. J. Leukoc. Biol. 2014, 96:305-312.
-
(2014)
J. Leukoc. Biol.
, vol.96
, pp. 305-312
-
-
Bollinger, T.1
Gies, S.2
Naujoks, J.3
Feldhoff, L.4
Bollinger, A.5
Solbach, W.6
Rupp, J.7
-
5
-
-
0042368882
-
The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses
-
Bracken C.P., Whitelaw M.L., Peet D.J. The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses. Cell. Mol. Life Sci. CMLS 2003, 60:1376-1393.
-
(2003)
Cell. Mol. Life Sci. CMLS
, vol.60
, pp. 1376-1393
-
-
Bracken, C.P.1
Whitelaw, M.L.2
Peet, D.J.3
-
6
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
Bruick R.K., McKnight S.L. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 2001, 294:1337-1340.
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
7
-
-
24144444133
-
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
-
Brunelle J.K., Bell E.L., Quesada N.M., Vercauteren K., Tiranti V., Zeviani M., Scarpulla R.C., Chandel N.S. Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell Metab. 2005, 1:409-414.
-
(2005)
Cell Metab.
, vol.1
, pp. 409-414
-
-
Brunelle, J.K.1
Bell, E.L.2
Quesada, N.M.3
Vercauteren, K.4
Tiranti, V.5
Zeviani, M.6
Scarpulla, R.C.7
Chandel, N.S.8
-
8
-
-
80053597754
-
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1α activity during prolonged hypoxia
-
Bruning U., Cerone L., Neufeld Z., Fitzpatrick S.F., Cheong A., Scholz C.C., Simpson D.A., Leonard M.O., Tambuwala M.M., Cummins E.P., Taylor C.T. MicroRNA-155 promotes resolution of hypoxia-inducible factor 1α activity during prolonged hypoxia. Mol. Cell. Biol. 2011, 31:4087-4096.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 4087-4096
-
-
Bruning, U.1
Cerone, L.2
Neufeld, Z.3
Fitzpatrick, S.F.4
Cheong, A.5
Scholz, C.C.6
Simpson, D.A.7
Leonard, M.O.8
Tambuwala, M.M.9
Cummins, E.P.10
Taylor, C.T.11
-
9
-
-
0035575975
-
Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions
-
Caldwell C.C., Kojima H., Lukashev D., Armstrong J., Farber M., Apasov S.G., Sitkovsky M.V. Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions. J. Immunol. 2001, 167:6140-6149.
-
(2001)
J. Immunol.
, vol.167
, pp. 6140-6149
-
-
Caldwell, C.C.1
Kojima, H.2
Lukashev, D.3
Armstrong, J.4
Farber, M.5
Apasov, S.G.6
Sitkovsky, M.V.7
-
10
-
-
84905510173
-
Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells
-
Cao Y., Rathmell J.C., Macintyre A.N. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS One 2014, 9:e104104.
-
(2014)
PLoS One
, vol.9
, pp. e104104
-
-
Cao, Y.1
Rathmell, J.C.2
Macintyre, A.N.3
-
11
-
-
0032578458
-
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
-
Chandel N.S., Maltepe E., Goldwasser E., Mathieu C.E., Simon M.C., Schumacker P.T. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:11715-11720.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 11715-11720
-
-
Chandel, N.S.1
Maltepe, E.2
Goldwasser, E.3
Mathieu, C.E.4
Simon, M.C.5
Schumacker, P.T.6
-
12
-
-
0034682786
-
2 sensing
-
2 sensing. J. Biol. Chem. 2000, 275:25130-25138.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25130-25138
-
-
Chandel, N.S.1
McClintock, D.S.2
Feliciano, C.E.3
Wood, T.M.4
Melendez, J.A.5
Rodriguez, A.M.6
Schumacker, P.T.7
-
13
-
-
84878831880
-
Posttranscriptional control of T cell effector function by aerobic glycolysis
-
Chang C.-H., Curtis Jonathan D., Maggi Leonard B., Faubert B., Villarino Alejandro V., O'sullivan D., Huang Stanley C.-C., van der Windt Gerritje J.W., Blagih J., Qui J., Weber Jason D., Pearce Edward J., Jones Russell G., Pearce Erika L. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 2013, 153:1239-1251.
-
(2013)
Cell
, vol.153
, pp. 1239-1251
-
-
Chang, C.-H.1
Curtis, J.D.2
Maggi, L.B.3
Faubert, B.4
Villarino, A.V.5
O'sullivan, D.6
Huang, S.C.-C.7
van der Windt, G.J.W.8
Blagih, J.9
Qui, J.10
Weber, J.D.11
Pearce, E.J.12
Jones, R.G.13
Pearce, E.L.14
-
14
-
-
84911201387
-
Molecular regulation of effector and memory T cell differentiation
-
Chang J.T., Wherry E.J., Goldrath A.W. Molecular regulation of effector and memory T cell differentiation. Nat. Immunol. 2014, 15:1104-1115.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1104-1115
-
-
Chang, J.T.1
Wherry, E.J.2
Goldrath, A.W.3
-
15
-
-
79961170194
-
Regulation of NF-κB induction by TCR/CD28
-
Cheng J., Montecalvo A., Kane L.P. Regulation of NF-κB induction by TCR/CD28. Immunol. Res. 2011, 50:113-117.
-
(2011)
Immunol. Res.
, vol.50
, pp. 113-117
-
-
Cheng, J.1
Montecalvo, A.2
Kane, L.P.3
-
16
-
-
77957810983
-
Stabilization of hypoxia-inducible factor-1α protein in hypoxia occurs independently of mitochondrial reactive oxygen species production
-
Chua Y.L., Dufour E., Dassa E.P., Rustin P., Jacobs H.T., Taylor C.T., Hagen T. Stabilization of hypoxia-inducible factor-1α protein in hypoxia occurs independently of mitochondrial reactive oxygen species production. J. Biol. Chem. 2010, 285:31277-31284.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 31277-31284
-
-
Chua, Y.L.1
Dufour, E.2
Dassa, E.P.3
Rustin, P.4
Jacobs, H.T.5
Taylor, C.T.6
Hagen, T.7
-
17
-
-
84867381718
-
Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
-
Clambey E.T., McNamee E.N., Westrich J.A., Glover L.E., Campbell E.L., Jedlicka P., Zoeten E.F.D., Cambier J.C., Stenmark K.R., Colgan S.P., Eltzschig H.K. Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:E2784-E2793.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. E2784-E2793
-
-
Clambey, E.T.1
McNamee, E.N.2
Westrich, J.A.3
Glover, L.E.4
Campbell, E.L.5
Jedlicka, P.6
Zoeten, E.F.D.7
Cambier, J.C.8
Stenmark, K.R.9
Colgan, S.P.10
Eltzschig, H.K.11
-
18
-
-
84928975351
-
IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity
-
Cui G., Staron Matthew M., Gray Simon M., Ho P.-C., Amezquita Robert A., Wu J., Kaech Susan M. IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity. Cell 2015, 161:750-761.
-
(2015)
Cell
, vol.161
, pp. 750-761
-
-
Cui, G.1
Staron, M.M.2
Gray, S.M.3
Ho, P.-C.4
Amezquita, R.A.5
Wu, J.6
Kaech, S.M.7
-
19
-
-
80052277906
-
Control of TH17/Treg balance by hypoxia-inducible factor 1
-
Dang E.V., Barbi J., Yang H.-Y., Jinasena D., Yu H., Zheng Y., Bordman Z., Fu J., Kim Y., Yen H.-R., Luo W., Zeller K., Shimoda L., Topalian S.L., Semenza G.L., Dang C.V., Pardoll D.M., Pan F. Control of TH17/Treg balance by hypoxia-inducible factor 1. Cell 2011, 146:772-784.
-
(2011)
Cell
, vol.146
, pp. 772-784
-
-
Dang, E.V.1
Barbi, J.2
Yang, H.-Y.3
Jinasena, D.4
Yu, H.5
Zheng, Y.6
Bordman, Z.7
Fu, J.8
Kim, Y.9
Yen, H.-R.10
Luo, W.11
Zeller, K.12
Shimoda, L.13
Topalian, S.L.14
Semenza, G.L.15
Dang, C.V.16
Pardoll, D.M.17
Pan, F.18
-
20
-
-
84861424521
-
An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbate diabetes
-
Darce J., Rudra D., Li L., Nishio J., Cipolletta D., Rudensky A.Y., Mathis D., Benoist C. An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbate diabetes. Immunity 2012, 36:731-741.
-
(2012)
Immunity
, vol.36
, pp. 731-741
-
-
Darce, J.1
Rudra, D.2
Li, L.3
Nishio, J.4
Cipolletta, D.5
Rudensky, A.Y.6
Mathis, D.7
Benoist, C.8
-
21
-
-
84886672916
-
Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
-
Doedens A.L., Phan A.T., Stradner M.H., Fujimoto J.K., Nguyen J.V., Yang E., Johnson R.S., Goldrath A.W. Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen. Nat. Immunol. 2013, 14:1173-1182.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 1173-1182
-
-
Doedens, A.L.1
Phan, A.T.2
Stradner, M.H.3
Fujimoto, J.K.4
Nguyen, J.V.5
Yang, E.6
Johnson, R.S.7
Goldrath, A.W.8
-
22
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein A.C.R., Gleadle J.M., McNeill L.A., Hewitson K.S., O'Rourke J., Mole D.R., Mukherji M., Metzen E., Wilson M.I., Dhanda A., Tian Y.-M., Masson N., Hamilton D.L., Jaakkola P., Barstead R., Hodgkin J., Maxwell P.H., Pugh C.W., Schofield C.J., Ratcliffe P.J. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001, 107:43-54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.R.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.-M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
23
-
-
84871861969
-
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells
-
Finlay D.K., Rosenzweig E., Sinclair L.V., Feijoo-Carnero C., Hukelmann J.L., Rolf J., Panteleyev A.A., Okkenhaug K., Cantrell D.A. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells. J. Exp. Med. 2012, 209:2441-2453.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 2441-2453
-
-
Finlay, D.K.1
Rosenzweig, E.2
Sinclair, L.V.3
Feijoo-Carnero, C.4
Hukelmann, J.L.5
Rolf, J.6
Panteleyev, A.A.7
Okkenhaug, K.8
Cantrell, D.A.9
-
24
-
-
0028359320
-
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer
-
Firth J.D., Ebert B.L., Pugh C.W., Ratcliffe P.J. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:6496-6500.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 6496-6500
-
-
Firth, J.D.1
Ebert, B.L.2
Pugh, C.W.3
Ratcliffe, P.J.4
-
25
-
-
84886721392
-
Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch
-
Gubser P.M., Bantug G.R., Razik L., Fischer M., Dimeloe S., Hoenger G., Durovic B., Jauch A., Hess C. Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch. Nat. Immunol. 2013, 14:1064-1072.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 1064-1072
-
-
Gubser, P.M.1
Bantug, G.R.2
Razik, L.3
Fischer, M.4
Dimeloe, S.5
Hoenger, G.6
Durovic, B.7
Jauch, A.8
Hess, C.9
-
26
-
-
24144493814
-
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
-
Guzy R.D., Hoyos B., Robin E., Chen H., Liu L., Mansfield K.D., Simon M.C., Hammerling U., Schumacker P.T. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab. 2005, 1:401-408.
-
(2005)
Cell Metab.
, vol.1
, pp. 401-408
-
-
Guzy, R.D.1
Hoyos, B.2
Robin, E.3
Chen, H.4
Liu, L.5
Mansfield, K.D.6
Simon, M.C.7
Hammerling, U.8
Schumacker, P.T.9
-
27
-
-
52649097448
-
The immunological genome project: networks of gene expression in immune cells
-
Heng T.S.P., Painter M.W., Elpek K., Lukacs-Kornek V., Mauermann N., Turley S.J., Koller D., Kim F.S., Wagers A.J., Asinovski N., Davis S., Fassett M., Feuerer M., Gray D.H.D., Haxhinasto S., Hill J.A., Hyatt G., Laplace C., Leatherbee K., Mathis D., Benoist C., Jianu R., Laidlaw D.H., Best J.A., Knell J., Goldrath A.W., Jarjoura J., Sun J.C., Zhu Y., Lanier L.L., Ergun A., Li Z., Collins J.J., Shinton S.A., Hardy R.R., Friedline R., Sylvia K., Kang J. The immunological genome project: networks of gene expression in immune cells. Nat. Immunol. 2008, 9:1091-1094.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1091-1094
-
-
Heng, T.S.P.1
Painter, M.W.2
Elpek, K.3
Lukacs-Kornek, V.4
Mauermann, N.5
Turley, S.J.6
Koller, D.7
Kim, F.S.8
Wagers, A.J.9
Asinovski, N.10
Davis, S.11
Fassett, M.12
Feuerer, M.13
Gray, D.H.D.14
Haxhinasto, S.15
Hill, J.A.16
Hyatt, G.17
Laplace, C.18
Leatherbee, K.19
Mathis, D.20
Benoist, C.21
Jianu, R.22
Laidlaw, D.H.23
Best, J.A.24
Knell, J.25
Goldrath, A.W.26
Jarjoura, J.27
Sun, J.C.28
Zhu, Y.29
Lanier, L.L.30
Ergun, A.31
Li, Z.32
Collins, J.J.33
Shinton, S.A.34
Hardy, R.R.35
Friedline, R.36
Sylvia, K.37
Kang, J.38
more..
-
28
-
-
84861927253
-
HIF-1 in T cells ameliorated dextran sodium sulfate-induced murine colitis
-
Higashiyama M., Hokari R., Hozumi H., Kurihara C., Ueda T., Watanabe C., Tomita K., Nakamura M., Komoto S., Okada Y., Kawaguchi A., Nagao S., Suematsu M., Goda N., Miura S. HIF-1 in T cells ameliorated dextran sodium sulfate-induced murine colitis. J. Leukoc. Biol. 2012, 91:901-909.
-
(2012)
J. Leukoc. Biol.
, vol.91
, pp. 901-909
-
-
Higashiyama, M.1
Hokari, R.2
Hozumi, H.3
Kurihara, C.4
Ueda, T.5
Watanabe, C.6
Tomita, K.7
Nakamura, M.8
Komoto, S.9
Okada, Y.10
Kawaguchi, A.11
Nagao, S.12
Suematsu, M.13
Goda, N.14
Miura, S.15
-
29
-
-
84923357982
-
Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo
-
Hsiao H.-W., Hsu T.-S., Liu W.-H., Hsieh W.-C., Chou T.-F., Wu Y.-J., Jiang S.-T., Lai M.-Z. Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo. Nat. Commun. 2015, 6.
-
(2015)
Nat. Commun.
, vol.6
-
-
Hsiao, H.-W.1
Hsu, T.-S.2
Liu, W.-H.3
Hsieh, W.-C.4
Chou, T.-F.5
Wu, Y.-J.6
Jiang, S.-T.7
Lai, M.-Z.8
-
30
-
-
84857542440
-
Dynamic regulation of Th17 differentiation by oxygen concentrations
-
Ikejiri A., Nagai S., Goda N., Kurebayashi Y., Osada-Oka M., Takubo K., Suda T., Koyasu S. Dynamic regulation of Th17 differentiation by oxygen concentrations. Int. Immunol. 2012, 24:137-146.
-
(2012)
Int. Immunol.
, vol.24
, pp. 137-146
-
-
Ikejiri, A.1
Nagai, S.2
Goda, N.3
Kurebayashi, Y.4
Osada-Oka, M.5
Takubo, K.6
Suda, T.7
Koyasu, S.8
-
31
-
-
23644448721
-
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability
-
Isaacs J.S., Jung Y.J., Mole D.R., Lee S., Torres-Cabala C., Chung Y.-L., Merino M., Trepel J., Zbar B., Toro J., Ratcliffe P.J., Linehan W.M., Neckers L. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer Cell 2005, 8:143-153.
-
(2005)
Cancer Cell
, vol.8
, pp. 143-153
-
-
Isaacs, J.S.1
Jung, Y.J.2
Mole, D.R.3
Lee, S.4
Torres-Cabala, C.5
Chung, Y.-L.6
Merino, M.7
Trepel, J.8
Zbar, B.9
Toro, J.10
Ratcliffe, P.J.11
Linehan, W.M.12
Neckers, L.13
-
32
-
-
0035917313
-
HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
-
Ivan M., Kondo K., Yang H., Kim W., Valiando J., Ohh M., Salic A., Asara J.M., Lane W.S., Kaelin W.G. HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001, 292:464.
-
(2001)
Science
, vol.292
, pp. 464
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin, W.G.10
-
33
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science 2001, 292:468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.-M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
v Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
34
-
-
84875777840
-
MicroRNA regulation of T-cell differentiation and function
-
Jeker L.T., Bluestone J.A. MicroRNA regulation of T-cell differentiation and function. Immunol. Rev. 2013, 253:65-81.
-
(2013)
Immunol. Rev.
, vol.253
, pp. 65-81
-
-
Jeker, L.T.1
Bluestone, J.A.2
-
35
-
-
84876684375
-
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
-
Kidani Y., Elsaesser H., Hock M.B., Vergnes L., Williams K.J., Argus J.P., Marbois B.N., Komisopoulou E., Wilson E.B., Osborne T.F., Graeber T.G., Reue K., Brooks D.G., Bensinger S.J. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat. Immunol. 2013, 14:489-499.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 489-499
-
-
Kidani, Y.1
Elsaesser, H.2
Hock, M.B.3
Vergnes, L.4
Williams, K.J.5
Argus, J.P.6
Marbois, B.N.7
Komisopoulou, E.8
Wilson, E.B.9
Osborne, T.F.10
Graeber, T.G.11
Reue, K.12
Brooks, D.G.13
Bensinger, S.J.14
-
36
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
-
Kim J.-w., Tchernyshyov I., Semenza G.L., Dang C.V. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006, 3:177-185.
-
(2006)
Cell Metab.
, vol.3
, pp. 177-185
-
-
Kim, J.-W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
37
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain: a hypoxic switch
-
Lando D., Peet D.J., Whelan D.A., Gorman J.J., Whitelaw M.L. Asparagine hydroxylation of the HIF transactivation domain: a hypoxic switch. Science 2002, 295:858-861.
-
(2002)
Science
, vol.295
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
38
-
-
0035966119
-
Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1α in activated T lymphocytes
-
Lukashev D., Caldwell C., Ohta A., Chen P., Sitkovsky M. Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1α in activated T lymphocytes. J. Biol. Chem. 2001, 276:48754-48763.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48754-48763
-
-
Lukashev, D.1
Caldwell, C.2
Ohta, A.3
Chen, P.4
Sitkovsky, M.5
-
39
-
-
33749512970
-
Cutting edge: hypoxia-inducible factor 1α and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes
-
Lukashev D., Klebanov B., Kojima H., Grinberg A., Ohta A., Berenfeld L., Wenger R.H., Ohta A., Sitkovsky M. Cutting edge: hypoxia-inducible factor 1α and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes. J. Immunol. 2006, 177:4962-4965.
-
(2006)
J. Immunol.
, vol.177
, pp. 4962-4965
-
-
Lukashev, D.1
Klebanov, B.2
Kojima, H.3
Grinberg, A.4
Ohta, A.5
Berenfeld, L.6
Wenger, R.H.7
Ohta, A.8
Sitkovsky, M.9
-
40
-
-
0035887011
-
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
-
Mahon P.C., Hirota K., Semenza G.L. FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev. 2001, 15:2675-2686.
-
(2001)
Genes Dev.
, vol.15
, pp. 2675-2686
-
-
Mahon, P.C.1
Hirota, K.2
Semenza, G.L.3
-
41
-
-
0037031808
-
Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3α Locus
-
Makino Y., Kanopka A., Wilson W.J., Tanaka H., Poellinger L. Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3α Locus. J. Biol. Chem. 2002, 277:32405-32408.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32405-32408
-
-
Makino, Y.1
Kanopka, A.2
Wilson, W.J.3
Tanaka, H.4
Poellinger, L.5
-
42
-
-
4344645563
-
Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-α-prolyl-4-hydroxylases
-
Marxsen Jan H., Stengel P., Doege K., Heikkinen P., Jokilehto T., Wagner T., Jelkmann W., Jaakkola P., Metzen E. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-α-prolyl-4-hydroxylases. Biochem. J. 2004, 381:761-767.
-
(2004)
Biochem. J.
, vol.381
, pp. 761-767
-
-
Marxsen, J.H.1
Stengel, P.2
Doege, K.3
Heikkinen, P.4
Jokilehto, T.5
Wagner, T.6
Jelkmann, W.7
Jaakkola, P.8
Metzen, E.9
-
43
-
-
84930576092
-
Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α
-
advance online publication
-
Mascanfroni I.D., Takenaka M.C., Yeste A., Patel B., Wu Y., Kenison J.E., Siddiqui S., Basso A.S., Otterbein L.E., Pardoll D.M., Pan F., Priel A., Clish C.B., Robson S.C., Quintana F.J. Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α. Nat. Med. 2015, advance online publication.
-
(2015)
Nat. Med.
-
-
Mascanfroni, I.D.1
Takenaka, M.C.2
Yeste, A.3
Patel, B.4
Wu, Y.5
Kenison, J.E.6
Siddiqui, S.7
Basso, A.S.8
Otterbein, L.E.9
Pardoll, D.M.10
Pan, F.11
Priel, A.12
Clish, C.B.13
Robson, S.C.14
Quintana, F.J.15
-
44
-
-
0037837724
-
Multiple splice variants of the human HIF-3α locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex
-
Maynard M.A., Qi H., Chung J., Lee E.H.L., Kondo Y., Hara S., Conaway R.C., Conaway J.W., Ohh M. Multiple splice variants of the human HIF-3α locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. J. Biol. Chem. 2003, 278:11032-11040.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11032-11040
-
-
Maynard, M.A.1
Qi, H.2
Chung, J.3
Lee, E.H.L.4
Kondo, Y.5
Hara, S.6
Conaway, R.C.7
Conaway, J.W.8
Ohh, M.9
-
45
-
-
33747691662
-
Transforming growth factor β1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression
-
McMahon S., Charbonneau M., Grandmont S., Richard D.E., Dubois C.M. Transforming growth factor β1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression. J. Biol. Chem. 2006, 281:24171-24181.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 24171-24181
-
-
McMahon, S.1
Charbonneau, M.2
Grandmont, S.3
Richard, D.E.4
Dubois, C.M.5
-
46
-
-
84876741058
-
Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function
-
McNamee E.N., Johnson D.K., Homann D., Clambey E.T. Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function. Immunol. Res. 2013, 55:58-70.
-
(2013)
Immunol. Res.
, vol.55
, pp. 58-70
-
-
McNamee, E.N.1
Johnson, D.K.2
Homann, D.3
Clambey, E.T.4
-
47
-
-
18844408840
-
Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element
-
Metzen E., Stiehl Daniel P., tiehl K., Doege J., Marxsen Jan H., Hellwig-Bürgel T., Jelkmann W. Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element. Biochem. J. 2005, 387:711-717.
-
(2005)
Biochem. J.
, vol.387
, pp. 711-717
-
-
Metzen, E.1
Stiehl, D.P.2
tiehl, K.3
Doege, J.4
Marxsen, J.H.5
Hellwig-Bürgel, T.6
Jelkmann, W.7
-
48
-
-
79953172571
-
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
-
Michalek R.D., Gerriets V.A., Jacobs S.R., Macintyre A.N., MacIver N.J., Mason E.F., Sullivan S.A., Nichols A.G., Rathmell J.C. Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. J. Immunol. 2011, 186:3299-3303.
-
(2011)
J. Immunol.
, vol.186
, pp. 3299-3303
-
-
Michalek, R.D.1
Gerriets, V.A.2
Jacobs, S.R.3
Macintyre, A.N.4
MacIver, N.J.5
Mason, E.F.6
Sullivan, S.A.7
Nichols, A.G.8
Rathmell, J.C.9
-
49
-
-
20444429440
-
TCR engagement increases hypoxia-inducible factor-1α protein synthesis via Rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells
-
Nakamura H., Makino Y., Okamoto K., Poellinger L., Ohnuma K., Morimoto C., Tanaka H. TCR engagement increases hypoxia-inducible factor-1α protein synthesis via Rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells. J. Immunol. 2005, 174:7592-7599.
-
(2005)
J. Immunol.
, vol.174
, pp. 7592-7599
-
-
Nakamura, H.1
Makino, Y.2
Okamoto, K.3
Poellinger, L.4
Ohnuma, K.5
Morimoto, C.6
Tanaka, H.7
-
50
-
-
84904392273
-
Memory CD8+ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development
-
O'Sullivan D., van der Windt Gerritje J.W., Huang Stanley C.-C., Curtis Jonathan D., Chang C.-H., Buck Michael D., Qiu J., Smith Amber M., Lam Wing Y., DiPlato Lisa M., Hsu F.-F., Birnbaum Morris J., Pearce Edward J., Pearce Erika L. Memory CD8+ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development. Immunity 2014, 41:75-88.
-
(2014)
Immunity
, vol.41
, pp. 75-88
-
-
O'Sullivan, D.1
van der Windt, G.J.W.2
Huang, S.C.-C.3
Curtis, J.D.4
Chang, C.-H.5
Buck, M.D.6
Qiu, J.7
Smith, A.M.8
Lam, W.Y.9
DiPlato, L.M.10
Hsu, F.-F.11
Birnbaum, M.J.12
Pearce, E.J.13
Pearce, E.L.14
-
51
-
-
84911132031
-
Bcl-6 directly represses the gene program of the glycolysis pathway
-
Oestreich K.J., Read K.A., Gilbertson S.E., Hough K.P., McDonald P.W., Krishnamoorthy V., Weinmann A.S. Bcl-6 directly represses the gene program of the glycolysis pathway. Nat. Immunol. 2014, 15:957-964.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 957-964
-
-
Oestreich, K.J.1
Read, K.A.2
Gilbertson, S.E.3
Hough, K.P.4
McDonald, P.W.5
Krishnamoorthy, V.6
Weinmann, A.S.7
-
52
-
-
84875785000
-
Role of microRNAs and long-non-coding RNAs in CD4+ T-cell differentiation
-
Pagani M., Rossetti G., Panzeri I., de Candia P., Bonnal R.J.P., Rossi R.L., Geginat J., Abrignani S. Role of microRNAs and long-non-coding RNAs in CD4+ T-cell differentiation. Immunol. Rev. 2013, 253:82-96.
-
(2013)
Immunol. Rev.
, vol.253
, pp. 82-96
-
-
Pagani, M.1
Rossetti, G.2
Panzeri, I.3
de Candia, P.4
Bonnal, R.J.P.5
Rossi, R.L.6
Geginat, J.7
Abrignani, S.8
-
53
-
-
84866335513
-
The HIF-1α hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
-
Palazón A., Martínez-Forero I., Teijeira A., Morales-Kastresana A., Alfaro C., Sanmamed M.F., Perez-Gracia J.L., Peñuelas I., Hervás-Stubbs S., Rouzaut A., d.Landázuri M.O., Jure-Kunkel M., Aragonés J., Melero I. The HIF-1α hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy. Cancer Discovery 2012, 2:608-623.
-
(2012)
Cancer Discovery
, vol.2
, pp. 608-623
-
-
Palazón, A.1
Martínez-Forero, I.2
Teijeira, A.3
Morales-Kastresana, A.4
Alfaro, C.5
Sanmamed, M.F.6
Perez-Gracia, J.L.7
Peñuelas, I.8
Hervás-Stubbs, S.9
Rouzaut, A.10
d Landázuri, M.O.11
Jure-Kunkel, M.12
Aragonés, J.13
Melero, I.14
-
54
-
-
84908141221
-
HIF transcription factors, inflammation, and immunity
-
Palazon A., Goldrath Ananda W., Nizet V., Johnson Randall S. HIF transcription factors, inflammation, and immunity. Immunity 2014, 41:518-528.
-
(2014)
Immunity
, vol.41
, pp. 518-528
-
-
Palazon, A.1
Goldrath, A.W.2
Nizet, V.3
Johnson, R.S.4
-
55
-
-
67649160600
-
Genome-wide identification of long noncoding RNAs in CD8+ T cells
-
Pang K.C., Dinger M.E., Mercer T.R., Malquori L., Grimmond S.M., Chen W., Mattick J.S. Genome-wide identification of long noncoding RNAs in CD8+ T cells. J. Immunol. 2009, 182:7738-7748.
-
(2009)
J. Immunol.
, vol.182
, pp. 7738-7748
-
-
Pang, K.C.1
Dinger, M.E.2
Mercer, T.R.3
Malquori, L.4
Grimmond, S.M.5
Chen, W.6
Mattick, J.S.7
-
56
-
-
84878592780
-
A new look at TCR signaling to NF-κB
-
Paul S., Schaefer B.C. A new look at TCR signaling to NF-κB. Trends Immunol. 2013, 34:269-281.
-
(2013)
Trends Immunol.
, vol.34
, pp. 269-281
-
-
Paul, S.1
Schaefer, B.C.2
-
57
-
-
84885670616
-
Fueling immunity: insights into metabolism and lymphocyte function
-
Pearce E.L., Poffenberger M.C., Chang C.-H., Jones R.G. Fueling immunity: insights into metabolism and lymphocyte function. Science 2013, 342:1242454.
-
(2013)
Science
, vol.342
, pp. 1242454
-
-
Pearce, E.L.1
Poffenberger, M.C.2
Chang, C.-H.3
Jones, R.G.4
-
58
-
-
23944454868
-
eso Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene
-
Pescador N., Cuevas Y., Naranjo S., Alcaide M., Villar D., Manuel O.L., andazuri L., del P., eso Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene. Biochem. J. 2005, 390:189-197.
-
(2005)
Biochem. J.
, vol.390
, pp. 189-197
-
-
Pescador, N.1
Cuevas, Y.2
Naranjo, S.3
Alcaide, M.4
Villar, D.5
Manuel, O.L.6
andazuri, L.7
del, P.8
-
59
-
-
22144492953
-
HIF-1α expression regulates the bactericidal capacity of phagocytes
-
Peyssonnaux C., Datta V., Cramer T., Doedens A., Theodorakis E.A., Gallo R.L., Hurtado-Ziola N., Nizet V., Johnson R.S. HIF-1α expression regulates the bactericidal capacity of phagocytes. J. Clin. Invest. 2005, 115:1806-1815.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1806-1815
-
-
Peyssonnaux, C.1
Datta, V.2
Cramer, T.3
Doedens, A.4
Theodorakis, E.A.5
Gallo, R.L.6
Hurtado-Ziola, N.7
Nizet, V.8
Johnson, R.S.9
-
60
-
-
84903277871
-
Integrating canonical and metabolic signalling programmes in the regulation of T cell responses
-
Pollizzi K.N., Powell J.D. Integrating canonical and metabolic signalling programmes in the regulation of T cell responses. Nat. Rev. Immunol. 2014, 14:435-446.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 435-446
-
-
Pollizzi, K.N.1
Powell, J.D.2
-
61
-
-
44849100198
-
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
-
Rius J., Guma M., Schachtrup C., Akassoglou K., Zinkernagel A.S., Nizet V., Johnson R.S., Haddad G.G., Karin M. NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α. Nature 2008, 453:807-811.
-
(2008)
Nature
, vol.453
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
Johnson, R.S.7
Haddad, G.G.8
Karin, M.9
-
63
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
-
Selak M.A., Armour S.M., MacKenzie E.D., Boulahbel H., Watson D.G., Mansfield K.D., Pan Y., Simon M.C., Thompson C.B., Gottlieb E. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase. Cancer Cell 2005, 7:77-85.
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
64
-
-
84897019542
-
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology
-
Semenza G.L. Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. Annu. Rev. Pathol.: Mech. Dis. 2014, 9:47-71.
-
(2014)
Annu. Rev. Pathol.: Mech. Dis.
, vol.9
, pp. 47-71
-
-
Semenza, G.L.1
-
65
-
-
84874242919
-
Mitochondria are required for antigen-specific T cell activation through reactive Oxygen species signaling
-
Sena Laura A., Li S., Jairaman A., Prakriya M., Ezponda T., Hildeman David A., Jonathan D.Licht H., Wang C.-R., Schumacker Paul T., Licht Jonathan D., Perlman H., Bryce Paul J., Chandel Navdeep S. Mitochondria are required for antigen-specific T cell activation through reactive Oxygen species signaling. Immunity 2013, 38:225-236.
-
(2013)
Immunity
, vol.38
, pp. 225-236
-
-
Sena, L.A.1
Li, S.2
Jairaman, A.3
Prakriya, M.4
Ezponda, T.5
Hildeman, D.A.6
Jonathan D.Licht, H.7
Wang, C.-R.8
Schumacker, P.T.9
Licht, J.D.10
Perlman, H.11
Bryce, P.J.12
Chandel, N.S.13
-
66
-
-
79960369458
-
HIF1α-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi L.Z., Wang R., Huang G., Vogel P., Neale G., Green D.R., Chi H. HIF1α-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. J. Exp. Med. 2011, 208:1367-1376.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1367-1376
-
-
Shi, L.Z.1
Wang, R.2
Huang, G.3
Vogel, P.4
Neale, G.5
Green, D.R.6
Chi, H.7
-
67
-
-
84885055994
-
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
-
Sukumar M., Liu J., Ji Y., Subramanian M., Crompton J.G., Yu Z., Roychoudhuri R., Palmer D.C., Muranski P., Karoly E.D., Mohney R.P., Klebanoff C.A., Lal A., Finkel T., Restifo N.P., Gattinoni L. Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function. J. Clin. Invest. 2013, 123:4479-4488.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 4479-4488
-
-
Sukumar, M.1
Liu, J.2
Ji, Y.3
Subramanian, M.4
Crompton, J.G.5
Yu, Z.6
Roychoudhuri, R.7
Palmer, D.C.8
Muranski, P.9
Karoly, E.D.10
Mohney, R.P.11
Klebanoff, C.A.12
Lal, A.13
Finkel, T.14
Restifo, N.P.15
Gattinoni, L.16
-
68
-
-
77649177217
-
Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis
-
Takeda N., O'Dea E.L., Doedens A., Kim J.-w, Weidemann A., Stockmann C., Asagiri M., Simon M.C., Hoffmann A., Johnson R.S. Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis. Genes Dev. 2010, 24:491-501.
-
(2010)
Genes Dev.
, vol.24
, pp. 491-501
-
-
Takeda, N.1
O'Dea, E.L.2
Doedens, A.3
Kim, J.-W.4
Weidemann, A.5
Stockmann, C.6
Asagiri, M.7
Simon, M.C.8
Hoffmann, A.9
Johnson, R.S.10
-
69
-
-
38149059911
-
Mitochondria and cellular oxygen sensing in the HIF pathway
-
Taylor Cormac T. Mitochondria and cellular oxygen sensing in the HIF pathway. Biochem. J. 2008, 409:19.
-
(2008)
Biochem. J.
, vol.409
, pp. 19
-
-
Taylor, C.T.1
-
70
-
-
80051925716
-
4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection
-
Vezys V., Penaloza-MacMaster P., Barber D.L., Ha S.-J., Konieczny B., Freeman G.J., Mittler R.S., Ahmed R. 4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection. J. Immunol. 2011, 187:1634-1642.
-
(2011)
J. Immunol.
, vol.187
, pp. 1634-1642
-
-
Vezys, V.1
Penaloza-MacMaster, P.2
Barber, D.L.3
Ha, S.-J.4
Konieczny, B.5
Freeman, G.J.6
Mittler, R.S.7
Ahmed, R.8
-
71
-
-
0017153683
-
Aerobic glycolysis during lymphocyte proliferation
-
Wang T., Marquardt C., Foker J. Aerobic glycolysis during lymphocyte proliferation. Nature 1976, 261:702-705.
-
(1976)
Nature
, vol.261
, pp. 702-705
-
-
Wang, T.1
Marquardt, C.2
Foker, J.3
-
72
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang R., Dillon C.P., Shi L.Z., Milasta S., Carter R., Finkelstein D., McCormick L.L., Fitzgerald P., Chi H., Munger J., Green D.R. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 2011, 35:871-882.
-
(2011)
Immunity
, vol.35
, pp. 871-882
-
-
Wang, R.1
Dillon, C.P.2
Shi, L.Z.3
Milasta, S.4
Carter, R.5
Finkelstein, D.6
McCormick, L.L.7
Fitzgerald, P.8
Chi, H.9
Munger, J.10
Green, D.R.11
-
73
-
-
84897051446
-
Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210
-
Wang H., Flach H., Onizawa M., Wei L., McManus M.T., Weiss A. Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210. Nat. Immunol. 2014, 15:393-401.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 393-401
-
-
Wang, H.1
Flach, H.2
Onizawa, M.3
Wei, L.4
McManus, M.T.5
Weiss, A.6
-
74
-
-
77955384915
-
Activation of hypoxia inducible factor 1 Is a general phenomenon in infections with human pathogens
-
Werth N., Beerlage C., Rosenberger C., Yazdi A.S., Edelmann M., Amr A., Bernhardt W., von Eiff C., Becker K., Schäfer A., Peschel A., Kempf V.A.J. Activation of hypoxia inducible factor 1 Is a general phenomenon in infections with human pathogens. PLoS One 2010, 5:e11576.
-
(2010)
PLoS One
, vol.5
, pp. e11576
-
-
Werth, N.1
Beerlage, C.2
Rosenberger, C.3
Yazdi, A.S.4
Edelmann, M.5
Amr, A.6
Bernhardt, W.7
von Eiff, C.8
Becker, K.9
Schäfer, A.10
Peschel, A.11
Kempf, V.A.J.12
-
75
-
-
84892364858
-
Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect
-
Yang F., Zhang H., Mei Y., Wu M. Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect. Mol. Cell 2014, 53:88-100.
-
(2014)
Mol. Cell
, vol.53
, pp. 88-100
-
-
Yang, F.1
Zhang, H.2
Mei, Y.3
Wu, M.4
-
76
-
-
84928641864
-
Normalization of CD4+ T cell metabolism reverses lupus
-
274ra218-274ra218
-
Yin Y., Choi S.-C., Xu Z., Perry D.J., Seay H., Croker B.P., Sobel E.S., Brusko T.M., Morel L. Normalization of CD4+ T cell metabolism reverses lupus. Sci. Transl. Med. 2015, 7. 274ra218-274ra218.
-
(2015)
Sci. Transl. Med.
, vol.7
-
-
Yin, Y.1
Choi, S.-C.2
Xu, Z.3
Perry, D.J.4
Seay, H.5
Croker, B.P.6
Sobel, E.S.7
Brusko, T.M.8
Morel, L.9
-
77
-
-
84856183120
-
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
-
van der Windt Gerritje J.W., Everts B., Chang C.-H., Curtis Jonathan D, Freitas Tori C, Amiel E., Pearce Edward J., Pearce Erika L. Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development. Immunity 2012, 36:68-78.
-
(2012)
Immunity
, vol.36
, pp. 68-78
-
-
van der Windt, G.J.W.1
Everts, B.2
Chang, C.-H.3
Curtis, J.D.4
Freitas, T.C.5
Amiel, E.6
Pearce, E.J.7
Pearce, E.L.8
-
78
-
-
84883423963
-
CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability
-
van der Windt G.J.W., O'Sullivan D., Everts B., Huang S.C.-C., Buck M.D., Curtis J.D., Chang C.-H., Smith A.M., Ai T., Faubert B., Jones R.G., Pearce E.J., Pearce E.L. CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:14336-14341.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 14336-14341
-
-
van der Windt, G.J.W.1
O'Sullivan, D.2
Everts, B.3
Huang, S.C.-C.4
Buck, M.D.5
Curtis, J.D.6
Chang, C.-H.7
Smith, A.M.8
Ai, T.9
Faubert, B.10
Jones, R.G.11
Pearce, E.J.12
Pearce, E.L.13
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