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Volumn 53, Issue 1, 2014, Pages 88-100

Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LONG UNTRANSLATED RNA; PROTEIN P21; VON HIPPEL LINDAU PROTEIN; HIF1A PROTEIN, HUMAN; RNA; TUMOR PROTEIN; VHL PROTEIN, HUMAN;

EID: 84892364858     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2013.11.004     Document Type: Article
Times cited : (469)

References (52)
  • 1
    • 35448982216 scopus 로고    scopus 로고
    • Hypoxia, glucose metabolism and the Warburg's effect
    • Bartrons R., Caro J. Hypoxia, glucose metabolism and the Warburg's effect. J. Bioenerg. Biomembr. 2007, 39:223-229.
    • (2007) J. Bioenerg. Biomembr. , vol.39 , pp. 223-229
    • Bartrons, R.1    Caro, J.2
  • 4
    • 70349478990 scopus 로고    scopus 로고
    • MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
    • Chan S.Y., Zhang Y.Y., Hemann C., Mahoney C.E., Zweier J.L., Loscalzo J. MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab. 2009, 10:273-284.
    • (2009) Cell Metab. , vol.10 , pp. 273-284
    • Chan, S.Y.1    Zhang, Y.Y.2    Hemann, C.3    Mahoney, C.E.4    Zweier, J.L.5    Loscalzo, J.6
  • 5
    • 62549117314 scopus 로고    scopus 로고
    • An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles
    • Clemson C.M., Hutchinson J.N., Sara S.A., Ensminger A.W., Fox A.H., Chess A., Lawrence J.B. An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol. Cell 2009, 33:717-726.
    • (2009) Mol. Cell , vol.33 , pp. 717-726
    • Clemson, C.M.1    Hutchinson, J.N.2    Sara, S.A.3    Ensminger, A.W.4    Fox, A.H.5    Chess, A.6    Lawrence, J.B.7
  • 6
    • 84858414020 scopus 로고    scopus 로고
    • Cellular metabolism and disease: what do metabolic outliers teach usα
    • DeBerardinis R.J., Thompson C.B. Cellular metabolism and disease: what do metabolic outliers teach usα. Cell 2012, 148:1132-1144.
    • (2012) Cell , vol.148 , pp. 1132-1144
    • DeBerardinis, R.J.1    Thompson, C.B.2
  • 8
    • 50149097983 scopus 로고    scopus 로고
    • Hypoxia, HIF1 and glucose metabolism in the solid tumour
    • Denko N.C. Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat. Rev. Cancer 2008, 8:705-713.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 705-713
    • Denko, N.C.1
  • 9
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • Esteller M. Non-coding RNAs in human disease. Nat. Rev. Genet. 2011, 12:861-874.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 861-874
    • Esteller, M.1
  • 10
    • 33744783432 scopus 로고    scopus 로고
    • Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
    • Fantin V.R., St-Pierre J., Leder P. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 2006, 9:425-434.
    • (2006) Cancer Cell , vol.9 , pp. 425-434
    • Fantin, V.R.1    St-Pierre, J.2    Leder, P.3
  • 11
    • 33947724515 scopus 로고    scopus 로고
    • HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
    • Fukuda R., Zhang H., Kim J.W., Shimoda L., Dang C.V., Semenza G.L. HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 2007, 129:111-122.
    • (2007) Cell , vol.129 , pp. 111-122
    • Fukuda, R.1    Zhang, H.2    Kim, J.W.3    Shimoda, L.4    Dang, C.V.5    Semenza, G.L.6
  • 12
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysisα
    • Gatenby R.A., Gillies R.J. Why do cancers have high aerobic glycolysisα. Nat. Rev. Cancer 2004, 4:891-899.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 13
    • 84863495094 scopus 로고    scopus 로고
    • The hallmarks of cancer: a long non-coding RNA point of view
    • Gutschner T., Diederichs S. The hallmarks of cancer: a long non-coding RNA point of view. RNA Biol. 2012, 9:703-719.
    • (2012) RNA Biol. , vol.9 , pp. 703-719
    • Gutschner, T.1    Diederichs, S.2
  • 14
    • 84884217184 scopus 로고    scopus 로고
    • Potential pathological and functional links between long noncoding RNAs and hematopoiesis
    • Han B.W., Chen Y.Q. Potential pathological and functional links between long noncoding RNAs and hematopoiesis. Sci. Signal. 2013, 6:re5.
    • (2013) Sci. Signal. , vol.6
    • Han, B.W.1    Chen, Y.Q.2
  • 15
    • 0345491599 scopus 로고    scopus 로고
    • Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
    • Hu C.J., Wang L.Y., Chodosh L.A., Keith B., Simon M.C. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol. Cell. Biol. 2003, 23:9361-9374.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 9361-9374
    • Hu, C.J.1    Wang, L.Y.2    Chodosh, L.A.3    Keith, B.4    Simon, M.C.5
  • 16
    • 84882448234 scopus 로고    scopus 로고
    • XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling
    • Huang X., Wu Z., Mei Y., Wu M. XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling. EMBO J. 2013, 32:2204-2216.
    • (2013) EMBO J. , vol.32 , pp. 2204-2216
    • Huang, X.1    Wu, Z.2    Mei, Y.3    Wu, M.4
  • 22
    • 33646739525 scopus 로고    scopus 로고
    • Ebola virus VP35-VP40 interaction is sufficient for packaging 3E-5E minigenome RNA into virus-like particles
    • Johnson R.F., McCarthy S.E., Godlewski P.J., Harty R.N. Ebola virus VP35-VP40 interaction is sufficient for packaging 3E-5E minigenome RNA into virus-like particles. J. Virol. 2006, 80:5135-5144.
    • (2006) J. Virol. , vol.80 , pp. 5135-5144
    • Johnson, R.F.1    McCarthy, S.E.2    Godlewski, P.J.3    Harty, R.N.4
  • 23
    • 84867420094 scopus 로고    scopus 로고
    • Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases
    • Kaelin W.G. Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases. Cold Spring Harb. Symp. Quant. Biol. 2011, 76:335-345.
    • (2011) Cold Spring Harb. Symp. Quant. Biol. , vol.76 , pp. 335-345
    • Kaelin, W.G.1
  • 24
    • 43649093915 scopus 로고    scopus 로고
    • Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway
    • Kaelin W.G., Ratcliffe P.J. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol. Cell 2008, 30:393-402.
    • (2008) Mol. Cell , vol.30 , pp. 393-402
    • Kaelin, W.G.1    Ratcliffe, P.J.2
  • 25
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
    • Kim J.W., Tchernyshyov I., Semenza G.L., Dang C.V. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006, 3:177-185.
    • (2006) Cell Metab. , vol.3 , pp. 177-185
    • Kim, J.W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 26
    • 0036527785 scopus 로고    scopus 로고
    • The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma
    • Maranchie J.K., Vasselli J.R., Riss J., Bonifacino J.S., Linehan W.M., Klausner R.D. The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma. Cancer Cell 2002, 1:247-255.
    • (2002) Cancer Cell , vol.1 , pp. 247-255
    • Maranchie, J.K.1    Vasselli, J.R.2    Riss, J.3    Bonifacino, J.S.4    Linehan, W.M.5    Klausner, R.D.6
  • 30
    • 80053911021 scopus 로고    scopus 로고
    • The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2
    • Mei Y., Hahn A.A., Hu S., Yang X. The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2. J. Biol. Chem. 2011, 286:35380-35387.
    • (2011) J. Biol. Chem. , vol.286 , pp. 35380-35387
    • Mei, Y.1    Hahn, A.A.2    Hu, S.3    Yang, X.4
  • 32
    • 84868664680 scopus 로고    scopus 로고
    • A central role for long non-coding RNA in cancer
    • Mitra S.A., Mitra A.P., Triche T.J. A central role for long non-coding RNA in cancer. Front. Genet. 2012, 3:17.
    • (2012) Front. Genet. , vol.3 , pp. 17
    • Mitra, S.A.1    Mitra, A.P.2    Triche, T.J.3
  • 34
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou I., Cairns R.A., Fontana L., Lim A.L., Denko N.C. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 2006, 3:187-197.
    • (2006) Cell Metab. , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 36
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1 alpha is required for solid tumor formation and embryonic vascularization
    • Ryan H.E., Lo J., Johnson R.S. HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J. 1998, 17:3005-3015.
    • (1998) EMBO J. , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 37
    • 80051752025 scopus 로고    scopus 로고
    • MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6
    • Saito K., Kondo E., Matsushita M. MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6. Nucleic Acids Res. 2011, 39:6086-6099.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 6086-6099
    • Saito, K.1    Kondo, E.2    Matsushita, M.3
  • 38
    • 16644363476 scopus 로고    scopus 로고
    • HIF-1 and p53: communication of transcription factors under hypoxia
    • Schmid T., Zhou J., Brüne B. HIF-1 and p53: communication of transcription factors under hypoxia. J. Cell. Mol. Med. 2004, 8:423-431.
    • (2004) J. Cell. Mol. Med. , vol.8 , pp. 423-431
    • Schmid, T.1    Zhou, J.2    Brüne, B.3
  • 39
    • 0032555217 scopus 로고    scopus 로고
    • A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor
    • Schoenfeld A., Davidowitz E.J., Burk R.D. A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor. Proc. Natl. Acad. Sci. USA 1998, 95:8817-8822.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8817-8822
    • Schoenfeld, A.1    Davidowitz, E.J.2    Burk, R.D.3
  • 41
    • 76349095132 scopus 로고    scopus 로고
    • Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
    • Semenza G.L. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 2010, 29:625-634.
    • (2010) Oncogene , vol.29 , pp. 625-634
    • Semenza, G.L.1
  • 42
    • 76049100577 scopus 로고    scopus 로고
    • HIF-1: upstream and downstream of cancer metabolism
    • Semenza G.L. HIF-1: upstream and downstream of cancer metabolism. Curr. Opin. Genet. Dev. 2010, 20:51-56.
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 51-56
    • Semenza, G.L.1
  • 43
    • 84859445000 scopus 로고    scopus 로고
    • Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
    • Semenza G.L. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Trends Pharmacol. Sci. 2012, 33:207-214.
    • (2012) Trends Pharmacol. Sci. , vol.33 , pp. 207-214
    • Semenza, G.L.1
  • 44
    • 77955291967 scopus 로고    scopus 로고
    • The altered metabolism of tumors: HIF-1 and its role in the Warburg effect
    • Stubbs M., Griffiths J.R. The altered metabolism of tumors: HIF-1 and its role in the Warburg effect. Adv. Enzyme Regul. 2010, 50:44-55.
    • (2010) Adv. Enzyme Regul. , vol.50 , pp. 44-55
    • Stubbs, M.1    Griffiths, J.R.2
  • 45
    • 60849139085 scopus 로고    scopus 로고
    • Metabolic enzymes as oncogenes or tumor suppressors
    • Thompson C.B. Metabolic enzymes as oncogenes or tumor suppressors. N. Engl. J. Med. 2009, 360:813-815.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 813-815
    • Thompson, C.B.1
  • 46
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956, 123:309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 47
    • 56349113455 scopus 로고    scopus 로고
    • 3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA
    • Wilusz J.E., Freier S.M., Spector D.L. 3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. Cell 2008, 135:919-932.
    • (2008) Cell , vol.135 , pp. 919-932
    • Wilusz, J.E.1    Freier, S.M.2    Spector, D.L.3
  • 48
    • 0032478823 scopus 로고    scopus 로고
    • Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression
    • Wood S.M., Wiesener M.S., Yeates K.M., Okada N., Pugh C.W., Maxwell P.H., Ratcliffe P.J. Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression. J. Biol. Chem. 1998, 273:8360-8368.
    • (1998) J. Biol. Chem. , vol.273 , pp. 8360-8368
    • Wood, S.M.1    Wiesener, M.S.2    Yeates, K.M.3    Okada, N.4    Pugh, C.W.5    Maxwell, P.H.6    Ratcliffe, P.J.7
  • 49
    • 84875810883 scopus 로고    scopus 로고
    • Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis
    • Yang F., Huo X.S., Yuan S.X., Zhang L., Zhou W.P., Wang F., Sun S.H. Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis. Mol. Cell 2013, 49:1083-1096.
    • (2013) Mol. Cell , vol.49 , pp. 1083-1096
    • Yang, F.1    Huo, X.S.2    Yuan, S.X.3    Zhang, L.4    Zhou, W.P.5    Wang, F.6    Sun, S.H.7
  • 50
    • 84876347286 scopus 로고    scopus 로고
    • Retinoic acid-induced HOXA5 expression is co-regulated by HuR and miR-130a
    • Yang F., Miao L., Mei Y., Wu M. Retinoic acid-induced HOXA5 expression is co-regulated by HuR and miR-130a. Cell. Signal. 2013, 25:1476-1485.
    • (2013) Cell. Signal. , vol.25 , pp. 1476-1485
    • Yang, F.1    Miao, L.2    Mei, Y.3    Wu, M.4


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