CRISPR/Cas9 system as an innovative genetic engineering tool: Enhancements in sequence specificity and delivery methods

Biochimica et Biophysica Acta - Reviews on Cancer

Volumn 1856, Issue 2, 2015, Pages 234-243

  Jo, Young Il ^a   Suresh, Bharathi ^b,c   Kim, Hyongbum ^b,c   Ramakrishna, Suresh ^d  

^a BRANDEIS UNIVERSITY   (United States)

^b Yonsei University College of Medicine   (South Korea)

^c Yonsei University   (South Korea)

^d Hanyang University   (South Korea)

Author keywords

CRISPR Cas9 applications; Delivery methods; Genome editing; Reduced off target effects; Sequence specificity; Therapeutics

Indexed keywords

CRISPR CAS SYSTEM; GENE DELIVERY SYSTEM; GENETIC ENGINEERING; GENOME ANALYSIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REVIEW; RNA EDITING; SEQUENCE ANALYSIS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETIC TRANSFECTION; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

CRISPR ASSOCIATED PROTEIN; DNA;

BASE SEQUENCE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA; GENETIC ENGINEERING; MOLECULAR SEQUENCE DATA; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TRANSFECTION;

EID: 84946430785     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2015.09.003     Document Type: Review

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