Current and future delivery systems for engineered nucleases: ZFN, TALEN and RGEN

Journal of Controlled Release

Volumn 205, Issue , 2015, Pages 120-127

  Ain, Qurrat Ul ^a   Chung, Jee Young ^a   Kim, Yong Hee ^a  

^a Hanyang University   (South Korea)

Author keywords

Engineered nucleases; Gene protein and cell therapy; Genome silencing vs genome editing; Viral and non viral delivery systems

Indexed keywords

GENE THERAPY; GENETIC ENGINEERING; NUCLEIC ACIDS; PROTEINS; TRANSCRIPTION;

CELL THERAPY; ENGINEERED NUCLEASES; GENOME ENGINEERING; GENOME MODIFICATION; HEREDITARY DISORDERS; NON-VIRAL DELIVERY SYSTEMS; TRANSCRIPTION ACTIVATORS; ZINC FINGER NUCLEASE;

GENES;

CRISPR ASSOCIATED PROTEIN; RIBONUCLEASE; ZINC FINGER PROTEIN;

ANIMAL; CHEMISTRY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS SYSTEM; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETICS; HUMAN; METABOLISM; PROCEDURES; PROTEIN ENGINEERING; TARGETED GENE REPAIR; VIRUS;

ANIMALS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; HUMANS; PROTEIN ENGINEERING; RIBONUCLEASES; TARGETED GENE REPAIR; VIRUSES; ZINC FINGERS;

EID: 84929672850     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.12.036     Document Type: Review

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