-
1
-
-
84918573386
-
Quercetin promotes cell apoptosis and inhibits the expression of MMP-9 and fibronectin via the AKT and ERK signalling pathways in human glioma cells
-
Pan HC, Jiang Q, Yu Y, et al. Quercetin promotes cell apoptosis and inhibits the expression of MMP-9 and fibronectin via the AKT and ERK signalling pathways in human glioma cells. Neurochem Int 2015;80:60-71.
-
(2015)
Neurochem Int
, vol.80
, pp. 60-71
-
-
Pan, H.C.1
Jiang, Q.2
Yu, Y.3
-
2
-
-
84882708117
-
Oleanolic acid suppresses migration and invasion of malignant glioma cells by inactivating MAPK/ERK signaling pathway
-
Guo G, Yao W, Zhang Q, Bo Y. Oleanolic acid suppresses migration and invasion of malignant glioma cells by inactivating MAPK/ERK signaling pathway. PLoS One 2013;8:e72079.
-
(2013)
PLoS One
, vol.8
, pp. e72079
-
-
Guo, G.1
Yao, W.2
Zhang, Q.3
Bo, Y.4
-
3
-
-
84861560573
-
Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway
-
Cha JH, Choi YJ, Cha SH, et al. Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway. Oncol Rep 2012;28:41-8.
-
(2012)
Oncol Rep
, vol.28
, pp. 41-48
-
-
Cha, J.H.1
Choi, Y.J.2
Cha, S.H.3
-
4
-
-
84928589094
-
Chloride intracellular channel 1 regulates prostate cancer cell proliferation and migration through the MAPK/ERK pathway
-
Tian Y, Guan Y, Jia Y, et al. Chloride intracellular channel 1 regulates prostate cancer cell proliferation and migration through the MAPK/ERK pathway. Cancer Biother Radiopharm 2014;29: 339-44.
-
(2014)
Cancer Biother Radiopharm
, vol.29
, pp. 339-344
-
-
Tian, Y.1
Guan, Y.2
Jia, Y.3
-
5
-
-
84899431027
-
Pterostilbene-isothiocyanate conjugate suppresses growth of prostate cancer cells irrespective of androgen receptor status
-
Nikhil K, Sharan S, Chakraborty A, Roy P. Pterostilbene-isothiocyanate conjugate suppresses growth of prostate cancer cells irrespective of androgen receptor status. PLoS One 2014;9:e93335.
-
(2014)
PLoS One
, vol.9
, pp. e93335
-
-
Nikhil, K.1
Sharan, S.2
Chakraborty, A.3
Roy, P.4
-
6
-
-
84874062469
-
Beta-elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/mTOR signalling pathways
-
Zhan YH, Liu J, Qu XJ, et al. Beta-elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/mTOR signalling pathways. Asian Pac J Cancer Prev 2012;13:2739-44.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 2739-2744
-
-
Zhan, Y.H.1
Liu, J.2
Qu, X.J.3
-
7
-
-
84908119474
-
Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance
-
Zheng Y, Wang X, Wang H, et al. Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance. Oncol Rep 2014;31:1669-76.
-
(2014)
Oncol Rep
, vol.31
, pp. 1669-1676
-
-
Zheng, Y.1
Wang, X.2
Wang, H.3
-
8
-
-
79953744330
-
Requirement of osteopontin in the migration and protection against taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells
-
Zhang R, Wang J, Ma S, et al. Requirement of osteopontin in the migration and protection against taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells. BMC Cell Biol 2011;12:11.
-
(2011)
BMC Cell Biol
, vol.12
, pp. 11
-
-
Zhang, R.1
Wang, J.2
Ma, S.3
-
9
-
-
70449627783
-
Salvia fruticosa, Salvia officinalis, and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: The role in MAPK/ERK pathway
-
Xavier CP, Lima CF, Fernandes-Ferreira M, Pereira-Wilson C. Salvia fruticosa, Salvia officinalis, and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: the role in MAPK/ERK pathway. Nutr Cancer 2009;61:564-71.
-
(2009)
Nutr Cancer
, vol.61
, pp. 564-571
-
-
Xavier, C.P.1
Lima, C.F.2
Fernandes-Ferreira, M.3
Pereira-Wilson, C.4
-
10
-
-
84866511129
-
Induction of apoptosis by laminarin, regulating the insulin-like growth factor-IR signaling pathways in HT-29 human colon cells
-
Park HK, Kim IH, Kim J, Nam TJ. Induction of apoptosis by laminarin, regulating the insulin-like growth factor-IR signaling pathways in HT-29 human colon cells. Int J Mol Med 2012;30: 734-8.
-
(2012)
Int J Mol Med
, vol.30
, pp. 734-738
-
-
Park, H.K.1
Kim, I.H.2
Kim, J.3
Nam, T.J.4
-
11
-
-
80052831113
-
Interferon-alpha sensitizes human gastric cancer cells to TRAIL-induced apoptosis via activation of the c-CBL-dependent MAPK/ERK pathway
-
Qu J, Zhao M, Teng Y, et al. Interferon-alpha sensitizes human gastric cancer cells to TRAIL-induced apoptosis via activation of the c-CBL-dependent MAPK/ERK pathway. Cancer Biol Ther 2011;12:494-502.
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 494-502
-
-
Qu, J.1
Zhao, M.2
Teng, Y.3
-
12
-
-
0034955201
-
Prolonged activation of mitogenactivated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells
-
Kim TI, Jin SH, Kim WH, et al. Prolonged activation of mitogenactivated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells. Int J Colorectal Dis 2001;16:167-73.
-
(2001)
Int J Colorectal Dis
, vol.16
, pp. 167-173
-
-
Kim, T.I.1
Jin, S.H.2
Kim, W.H.3
-
13
-
-
1842685183
-
Enhancement of peripheral benzodiazepine receptor ligand-induced apoptosis and cell cycle arrest of esophageal cancer cells by simultaneous inhibition of MAPK/ERK kinase
-
Sutter AP, Maaser K, Gerst B, et al. Enhancement of peripheral benzodiazepine receptor ligand-induced apoptosis and cell cycle arrest of esophageal cancer cells by simultaneous inhibition of MAPK/ERK kinase. Biochem Pharmacol 2004;67:1701-10.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1701-1710
-
-
Sutter, A.P.1
Maaser, K.2
Gerst, B.3
-
14
-
-
84896754240
-
Local anesthetics induce apoptosis in human thyroid cancer cells through the mitogenactivated protein kinase pathway
-
Chang YC, Hsu YC, Liu CL, et al. Local anesthetics induce apoptosis in human thyroid cancer cells through the mitogenactivated protein kinase pathway. PLoS One 2014;9:e89563.
-
(2014)
PLoS One
, vol.9
, pp. e89563
-
-
Chang, Y.C.1
Hsu, Y.C.2
Liu, C.L.3
-
15
-
-
77954675751
-
Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
-
Roy SK, Srivastava RK, Shankar S. Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer. J Mol Signal 2010;5:10.
-
(2010)
J Mol Signal
, vol.5
, pp. 10
-
-
Roy, S.K.1
Srivastava, R.K.2
Shankar, S.3
-
16
-
-
84873343223
-
PKI 166 induced redox signalling and apoptosis through activation of p53, MAP kinase and caspase pathway in epidermoid carcinoma
-
Das S, Dey KK, Bharti R, et al. PKI 166 induced redox signalling and apoptosis through activation of p53, MAP kinase and caspase pathway in epidermoid carcinoma. J Exp Ther Oncol 2012;10: 139-53.
-
(2012)
J Exp Ther Oncol
, vol.10
, pp. 139-153
-
-
Das, S.1
Dey, K.K.2
Bharti, R.3
-
17
-
-
84876448099
-
Sorafenib inhibits lymphoma xenografts by targeting MAPK/ERK and AKT pathways in tumor and vascular cells
-
Carlo-Stella C, Locatelli SL, Giacomini A, et al. Sorafenib inhibits lymphoma xenografts by targeting MAPK/ERK and AKT pathways in tumor and vascular cells. PLoS One 2013;8:e61603.
-
(2013)
PLoS One
, vol.8
, pp. e61603
-
-
Carlo-Stella, C.1
Locatelli, S.L.2
Giacomini, A.3
-
18
-
-
84873679971
-
ERK1/2 activation mediated by the nutlin3induced mitochondrial translocation of p53
-
Lee SY, Shin SJ, Kim HS. ERK1/2 activation mediated by the nutlin3induced mitochondrial translocation of p53. Int J Oncol 2013;42:1027-35.
-
(2013)
Int J Oncol
, vol.42
, pp. 1027-1035
-
-
Lee, S.Y.1
Shin, S.J.2
Kim, H.S.3
-
19
-
-
84872164775
-
Mirk/Dyrk1B mediates G0/G1 to S phase cell cycle progression and cell survival involving MAPK/ERK signaling in human cancer cells
-
Gao J, Zhao Y, Lv Y, et al. Mirk/Dyrk1B mediates G0/G1 to S phase cell cycle progression and cell survival involving MAPK/ERK signaling in human cancer cells. Cancer Cell Int 2013;13:2.
-
(2013)
Cancer Cell Int
, vol.13
, pp. 2
-
-
Gao, J.1
Zhao, Y.2
Lv, Y.3
-
20
-
-
78651245212
-
Down-regulation of TSG101 by small interfering RNA inhibits the proliferation of breast cancer cells through the MAPK/ERK signal pathway
-
Zhang Y, Song M, Cui ZS, et al. Down-regulation of TSG101 by small interfering RNA inhibits the proliferation of breast cancer cells through the MAPK/ERK signal pathway. Histol Histopathol 2011;26:87-94.
-
(2011)
Histol Histopathol
, vol.26
, pp. 87-94
-
-
Zhang, Y.1
Song, M.2
Cui, Z.S.3
-
21
-
-
78649644992
-
DNA damageinduced modulation of GLUT3 expression is mediated through p53-independent extracellular signal-regulated kinase signaling in HeLa cells
-
Watanabe M, Naraba H, Sakyo T, Kitagawa T. DNA damageinduced modulation of GLUT3 expression is mediated through p53-independent extracellular signal-regulated kinase signaling in HeLa cells. Mol Cancer Res 2010;8:1547-57.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1547-1557
-
-
Watanabe, M.1
Naraba, H.2
Sakyo, T.3
Kitagawa, T.4
-
22
-
-
77953702943
-
ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells
-
Sarkar S, Mazumdar A, Dash R, et al. ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells. Cancer Biol Ther 2010;9:592-603.
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 592-603
-
-
Sarkar, S.1
Mazumdar, A.2
Dash, R.3
-
23
-
-
84911912245
-
Knockdown of galectin-1 suppresses the growth and invasion of osteosarcoma cells through inhibition of the MAPK/ERK pathway
-
Miao JH, Wang SQ, Zhang MH, et al. Knockdown of galectin-1 suppresses the growth and invasion of osteosarcoma cells through inhibition of the MAPK/ERK pathway. Oncol Rep 2014;32: 1497-504.
-
(2014)
Oncol Rep
, vol.32
, pp. 1497-1504
-
-
Miao, J.H.1
Wang, S.Q.2
Zhang, M.H.3
-
24
-
-
84862829824
-
Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3beta
-
Choi CH, Lee BH, Ahn SG, Oh SH. Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3beta. Biochem Biophys Res Commun 2012;418:759-64.
-
(2012)
Biochem Biophys Res Commun
, vol.418
, pp. 759-764
-
-
Choi, C.H.1
Lee, B.H.2
Ahn, S.G.3
Oh, S.H.4
-
25
-
-
84863116491
-
Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways
-
Chang MC, Chen CA, Chen PJ, et al. Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways. Biochem J 2012;442:293-302.
-
(2012)
Biochem J
, vol.442
, pp. 293-302
-
-
Chang, M.C.1
Chen, C.A.2
Chen, P.J.3
-
26
-
-
79960962433
-
Targeting inflammatory kinase as an adjuvant treatment for osteosarcomas
-
Noh K, Kim KO, Patel NR, et al. Targeting inflammatory kinase as an adjuvant treatment for osteosarcomas. J Bone Joint Surg Am 2011;93:723-32.
-
(2011)
J Bone Joint Surg Am
, vol.93
, pp. 723-732
-
-
Noh, K.1
Kim, K.O.2
Patel, N.R.3
-
27
-
-
78049295535
-
STAT3 activation induced by Epstein-Barr virus latent membrane protein1 causes vascular endothelial growth factor expression and cellular invasiveness via JAK3 and ERK signaling
-
Wang Z, Luo F, Li L, et al. STAT3 activation induced by Epstein-Barr virus latent membrane protein1 causes vascular endothelial growth factor expression and cellular invasiveness via JAK3 And ERK signaling. Eur J Cancer 2010;46:2996-3006.
-
(2010)
Eur J Cancer
, vol.46
, pp. 2996-3006
-
-
Wang, Z.1
Luo, F.2
Li, L.3
-
28
-
-
4043152098
-
HLA-DR signaling inhibits Fas-mediated apoptosis in A375 melanoma cells
-
Aoudjit F, Guo W, Gagnon-Houde JV, et al. HLA-DR signaling inhibits Fas-mediated apoptosis in A375 melanoma cells. Exp Cell Res 2004;299:79-90.
-
(2004)
Exp Cell Res
, vol.299
, pp. 79-90
-
-
Aoudjit, F.1
Guo, W.2
Gagnon-Houde, J.V.3
-
29
-
-
84939171516
-
Calcitonin gene-related peptide regulates cardiomyocyte survival through regulation of oxidative stress by PI3K/Akt and MAPK signaling pathways
-
Umoh NA, Walker RK, Millis RM, et al. Calcitonin gene-related peptide regulates cardiomyocyte survival through regulation of oxidative stress by PI3K/Akt and MAPK signaling pathways. Ann Clin Exp Hypertens 2014;2:1007.
-
(2014)
Ann Clin Exp Hypertens
, vol.2
, pp. 1007
-
-
Umoh, N.A.1
Walker, R.K.2
Millis, R.M.3
-
30
-
-
2542433090
-
Protein phosphatase 2A-mediated cross-talk between p38 MAPK and ERK in apoptosis of cardiac myocytes
-
Liu Q, Hofmann PA. Protein phosphatase 2A-mediated cross-talk between p38 MAPK and ERK in apoptosis of cardiac myocytes. Am J Physiol Heart Circ Physiol 2004;286:H2204-12.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
, pp. H2204-H2212
-
-
Liu, Q.1
Hofmann, P.A.2
-
31
-
-
84895069289
-
Downregulation of miR-133 via MAPK/ERK signaling pathway involved in nicotine-induced cardiomyocyte apoptosis
-
Wang L, Li X, Zhou Y, et al. Downregulation of miR-133 via MAPK/ERK signaling pathway involved in nicotine-induced cardiomyocyte apoptosis. Naunyn Schmiedebergs Arch Pharmacol 2014;387:197-206.
-
(2014)
Naunyn Schmiedebergs Arch Pharmacol
, vol.387
, pp. 197-206
-
-
Wang, L.1
Li, X.2
Zhou, Y.3
-
32
-
-
84885131322
-
NME1 suppression promotes growth, adhesion and implantation of endometrial stromal cells via Akt and MAPK/Erk1/2 signal pathways in the endometriotic milieu
-
Li MQ, Shao J, Meng YH, et al. NME1 suppression promotes growth, adhesion and implantation of endometrial stromal cells via Akt and MAPK/Erk1/2 signal pathways in the endometriotic milieu. Hum Reprod 2013;28:2822-31.
-
(2013)
Hum Reprod
, vol.28
, pp. 2822-2831
-
-
Li, M.Q.1
Shao, J.2
Meng, Y.H.3
-
33
-
-
84871343104
-
Regulation of endothelial MAPK/ERK signalling and capillary morphogenesis by low-amplitude electric field
-
Sheikh AQ, Taghian T, Hemingway B, et al. Regulation of endothelial MAPK/ERK signalling and capillary morphogenesis by low-amplitude electric field. J R Soc Interface 2013;10:20120548.
-
(2013)
J R Soc Interface
, vol.10
, pp. 20120548
-
-
Sheikh, A.Q.1
Taghian, T.2
Hemingway, B.3
-
34
-
-
0033558798
-
VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
-
Gupta K, Kshirsagar S, Li W, et al. VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Exp Cell Res 1999;247: 495-504.
-
(1999)
Exp Cell Res
, vol.247
, pp. 495-504
-
-
Gupta, K.1
Kshirsagar, S.2
Li, W.3
-
35
-
-
77956781486
-
Vasopressin protects hippocampal neurones in culture against nutrient deprivation or glutamate-induced apoptosis
-
Chen J, Aguilera G. Vasopressin protects hippocampal neurones in culture against nutrient deprivation or glutamate-induced apoptosis. J Neuroendocrinol 2010;22:1072-81.
-
(2010)
J Neuroendocrinol
, vol.22
, pp. 1072-1081
-
-
Chen, J.1
Aguilera, G.2
-
36
-
-
84901036261
-
Zeaxanthin induces Nrf2-mediated phase II enzymes in protection of cell death
-
Zou X, Gao J, Zheng Y, et al. Zeaxanthin induces Nrf2-mediated phase II enzymes in protection of cell death. Cell Death Dis 2014;5: e1218.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1218
-
-
Zou, X.1
Gao, J.2
Zheng, Y.3
-
37
-
-
84893341891
-
Plasmalogens rescue neuronal cell death through an activation of AKT and ERK survival signaling
-
Hossain MS, Ifuku M, Take S, et al. Plasmalogens rescue neuronal cell death through an activation of AKT and ERK survival signaling. PLoS One 2013;8:e83508.
-
(2013)
PLoS One
, vol.8
, pp. e83508
-
-
Hossain, M.S.1
Ifuku, M.2
Take, S.3
-
38
-
-
84874595915
-
Bis(propyl)-cognitin protects against glutamate-induced neuro-excitotoxicity via concurrent regulation of NO, MAPK/ERK and PI3-K/Akt/GSK3beta pathways
-
Hu S, Cui W, Mak S, et al. Bis(propyl)-cognitin protects against glutamate-induced neuro-excitotoxicity via concurrent regulation of NO, MAPK/ERK and PI3-K/Akt/GSK3beta pathways. Neurochem Int 2013;62:468-77.
-
(2013)
Neurochem Int
, vol.62
, pp. 468-477
-
-
Hu, S.1
Cui, W.2
Mak, S.3
-
39
-
-
80052615268
-
Extracellular HMGB1 released by NMDA treatment confers neuronal apoptosis via RAGE-p38 MAPK/ERK signaling pathway
-
Kim SW, Lim CM, Kim JB, et al. Extracellular HMGB1 released by NMDA treatment confers neuronal apoptosis via RAGE-p38 MAPK/ERK signaling pathway. Neurotox Res 2011;20:159-69.
-
(2011)
Neurotox Res
, vol.20
, pp. 159-169
-
-
Kim, S.W.1
Lim, C.M.2
Kim, J.B.3
-
40
-
-
48249106653
-
Brain-derived neurotrophic factor stimulates the neural differentiation of human umbilical cord bloodderived mesenchymal stem cells and survival of differentiated cells through MAPK/ERK and PI3K/Akt-dependent signaling pathways
-
Lim JY, Park SI, Oh JH, et al. Brain-derived neurotrophic factor stimulates the neural differentiation of human umbilical cord bloodderived mesenchymal stem cells and survival of differentiated cells through MAPK/ERK and PI3K/Akt-dependent signaling pathways. J Neurosci Res 2008;86:2168-78.
-
(2008)
J Neurosci Res
, vol.86
, pp. 2168-2178
-
-
Lim, J.Y.1
Park, S.I.2
Oh, J.H.3
-
41
-
-
0141884369
-
Substance P protects spiral ganglion neurons from apoptosis via PKC-Ca2+-MAPK/ERK pathways
-
Lallemend F, Lefebvre PP, Hans G, et al. Substance P protects spiral ganglion neurons from apoptosis via PKC-Ca2+-MAPK/ERK pathways. J Neurochem 2003;87:508-21.
-
(2003)
J Neurochem
, vol.87
, pp. 508-521
-
-
Lallemend, F.1
Lefebvre, P.P.2
Hans, G.3
-
42
-
-
0033556356
-
A role for MAPK/ERK in sympathetic neuron survival: Protection against a p53-dependent, JNKindependent induction of apoptosis by cytosine arabinoside
-
Anderson CN, Tolkovsky AM. A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNKindependent induction of apoptosis by cytosine arabinoside. J Neurosci 1999;19:664-73.
-
(1999)
J Neurosci
, vol.19
, pp. 664-673
-
-
Anderson, C.N.1
Tolkovsky, A.M.2
-
43
-
-
84876005139
-
TNFalpha induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway
-
Marques-Fernandez F, Planells-Ferrer L, Gozzelino R, et al. TNFalpha induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway. Cell Death Dis 2013;4:e493.
-
(2013)
Cell Death Dis
, vol.4
, pp. e493
-
-
Marques-Fernandez, F.1
Planells-Ferrer, L.2
Gozzelino, R.3
-
44
-
-
84878441683
-
Neuroprotection of interleukin- 6 against NMDA-induced neurotoxicity is mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT signaling pathways
-
Fang XX, Jiang XL, Han XH, et al. Neuroprotection of interleukin- 6 against NMDA-induced neurotoxicity is mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT signaling pathways. Cell Mol Neurobiol 2013;33:241-51.
-
(2013)
Cell Mol Neurobiol
, vol.33
, pp. 241-251
-
-
Fang, X.X.1
Jiang, X.L.2
Han, X.H.3
-
45
-
-
84871948613
-
Protective effects of 7,8-dihydroxyflavone on retinal ganglion and RGC-5 cells against excitotoxic and oxidative stress
-
Gupta VK, You Y, Li JC, et al. Protective effects of 7,8-dihydroxyflavone on retinal ganglion and RGC-5 cells against excitotoxic and oxidative stress. J Mol Neurosci 2013;49:96-104.
-
(2013)
J Mol Neurosci
, vol.49
, pp. 96-104
-
-
Gupta, V.K.1
You, Y.2
Li, J.C.3
-
46
-
-
84865318675
-
Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo
-
Zhao Y, Luo P, Guo Q, et al. Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo. Exp Neurol 2012;237:489-98.
-
(2012)
Exp Neurol
, vol.237
, pp. 489-498
-
-
Zhao, Y.1
Luo, P.2
Guo, Q.3
-
47
-
-
84872362045
-
The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
-
Bravo-San Pedro JM, Niso-Santano M, Gomez-Sanchez R, et al. The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway. Cell Mol Life Sci 2013;70: 121-36.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 121-136
-
-
Bravo-San Pedro, J.M.1
Niso-Santano, M.2
Gomez-Sanchez, R.3
-
48
-
-
84937966766
-
Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells
-
Ozcan Z, Gul G, Yaman I. Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells. Arch Toxicol DOI: 10.1007/s00204-014-1311-x.
-
Arch Toxicol
-
-
Ozcan, Z.1
Gul, G.2
Yaman, I.3
-
49
-
-
84870699469
-
Zinc inhibits high glucose-induced apoptosis in peritoneal mesothelial cells
-
Zhang X, Liang D, Guo B, et al. Zinc inhibits high glucose-induced apoptosis in peritoneal mesothelial cells. Biol Trace Elem Res 2012;150:424-32.
-
(2012)
Biol Trace Elem Res
, vol.150
, pp. 424-432
-
-
Zhang, X.1
Liang, D.2
Guo, B.3
-
50
-
-
84864288333
-
Celecoxib inhibits growth of human autosomal dominant polycystic kidney cyst-lining epithelial cells through the VEGF/Raf/MAPK/ERK signaling pathway
-
Xu T, Wang NS, Fu LL, et al. Celecoxib inhibits growth of human autosomal dominant polycystic kidney cyst-lining epithelial cells through the VEGF/Raf/MAPK/ERK signaling pathway. Mol Biol Rep 2012;39:7743-53.
-
(2012)
Mol Biol Rep
, vol.39
, pp. 7743-7753
-
-
Xu, T.1
Wang, N.S.2
Fu, L.L.3
-
51
-
-
77954621422
-
Trichostatin a prevents TGF-beta1-induced apoptosis by inhibiting ERK activation in human renal tubular epithelial cells
-
Yoshikawa M, Hishikawa K, Idei M, Fujita T. Trichostatin a prevents TGF-beta1-induced apoptosis by inhibiting ERK activation in human renal tubular epithelial cells. Eur J Pharmacol 2010; 642:28-36.
-
(2010)
Eur J Pharmacol
, vol.642
, pp. 28-36
-
-
Yoshikawa, M.1
Hishikawa, K.2
Idei, M.3
Fujita, T.4
-
52
-
-
84865181154
-
Effect of mitofusin 2 overexpression on the proliferation and apoptosis of high-glucoseinduced rat glomerular mesangial cells
-
Wan-Xin T, Tian-Lei C, Ben W, et al. Effect of mitofusin 2 overexpression on the proliferation and apoptosis of high-glucoseinduced rat glomerular mesangial cells. J Nephrol 2012;25: 1023-30.
-
(2012)
J Nephrol
, vol.25
, pp. 1023-1030
-
-
Wan-Xin, T.1
Tian-Lei, C.2
Ben, W.3
-
53
-
-
12344324705
-
MEK inhibitor, U0126, attenuates cisplatin-induced renal injury by decreasing inflammation and apoptosis
-
Jo SK, Cho WY, Sung SA, et al. MEK inhibitor, U0126, attenuates cisplatin-induced renal injury by decreasing inflammation and apoptosis. Kidney Int 2005;67:458-66.
-
(2005)
Kidney Int
, vol.67
, pp. 458-466
-
-
Jo, S.K.1
Cho, W.Y.2
Sung, S.A.3
-
55
-
-
0037105386
-
Mitogenactivated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8
-
Soderstrom TS, Poukkula M, Holmstrom TH, et al. Mitogenactivated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8. J Immunol 2002;169:2851-60.
-
(2002)
J Immunol
, vol.169
, pp. 2851-2860
-
-
Soderstrom, T.S.1
Poukkula, M.2
Holmstrom, T.H.3
-
56
-
-
0034675853
-
MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly
-
Holmstrom TH, Schmitz I, Soderstrom TS, et al. MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly. EMBO J 2000;19:5418-28.
-
(2000)
EMBO J
, vol.19
, pp. 5418-5428
-
-
Holmstrom, T.H.1
Schmitz, I.2
Soderstrom, T.S.3
-
57
-
-
84880840009
-
Erythropoietin protects epithelial cells from excessive autophagy and apoptosis in experimental neonatal necrotizing enterocolitis
-
Yu Y, Shiou SR, Guo Y, et al. Erythropoietin protects epithelial cells from excessive autophagy and apoptosis in experimental neonatal necrotizing enterocolitis. PLoS One 2013;8:e69620.
-
(2013)
PLoS One
, vol.8
, pp. e69620
-
-
Yu, Y.1
Shiou, S.R.2
Guo, Y.3
-
58
-
-
84865972087
-
Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway
-
Tseng HL, Li CJ, Huang LH, et al. Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway. Toxicol Appl Pharmacol 2012;264:104-13.
-
(2012)
Toxicol Appl Pharmacol
, vol.264
, pp. 104-113
-
-
Tseng, H.L.1
Li, C.J.2
Huang, L.H.3
-
59
-
-
84878015872
-
Icaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways
-
Li Q, Huai L, Zhang C, et al. Icaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways. Int J Hematol 2013;97:617-23.
-
(2013)
Int J Hematol
, vol.97
, pp. 617-623
-
-
Li, Q.1
Huai, L.2
Zhang, C.3
-
60
-
-
84867329976
-
Combination of low doses of enzastaurin and lenalidomide has synergistic activity in Bnon-Hodgkin lymphoma cell lines
-
Cosenza M, Civallero M, Grisendi G, et al. Combination of low doses of enzastaurin and lenalidomide has synergistic activity in Bnon-Hodgkin lymphoma cell lines. Ann Hematol 2012;91:1613-22.
-
(2012)
Ann Hematol
, vol.91
, pp. 1613-1622
-
-
Cosenza, M.1
Civallero, M.2
Grisendi, G.3
-
61
-
-
84861203790
-
Alpha2beta1 integrin promotes chemoresistance against doxorubicin in cancer cells through extracellular signal-regulated kinase (ERK)
-
Naci D, El Azreq MA, Chetoui N, et al. alpha2beta1 integrin promotes chemoresistance against doxorubicin in cancer cells through extracellular signal-regulated kinase (ERK). J Biol Chem 2012;287:17065-76.
-
(2012)
J Biol Chem
, vol.287
, pp. 17065-17076
-
-
Naci, D.1
El Azreq, M.A.2
Chetoui, N.3
-
62
-
-
80052074643
-
Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1
-
Herishanu Y, Gibellini F, Njuguna N, et al. Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1. Leuk Lymphoma 2011;52:1758-69.
-
(2011)
Leuk Lymphoma
, vol.52
, pp. 1758-1769
-
-
Herishanu, Y.1
Gibellini, F.2
Njuguna, N.3
-
63
-
-
33750485389
-
Inhibition of the ERK pathway promotes apoptosis induced by 2-chloro-2′-deoxyadenosine in the B-cell leukemia cell line EHEB
-
Smal C, Lisart S, Ferrant A, et al. Inhibition of the ERK pathway promotes apoptosis induced by 2-chloro-2′-deoxyadenosine in the B-cell leukemia cell line EHEB. Nucleosides Nucleotides Nucleic Acids 2006;25:1009-12.
-
(2006)
Nucleosides Nucleotides Nucleic Acids
, vol.25
, pp. 1009-1012
-
-
Smal, C.1
Lisart, S.2
Ferrant, A.3
-
64
-
-
23744476932
-
SET-induced calcium signaling and MAPK/ERK pathway activation mediate dendritic cell-like differentiation of U937 cells
-
Kandilci A, Grosveld GC. SET-induced calcium signaling and MAPK/ERK pathway activation mediate dendritic cell-like differentiation of U937 cells. Leukemia 2005;19:1439-45.
-
(2005)
Leukemia
, vol.19
, pp. 1439-1445
-
-
Kandilci, A.1
Grosveld, G.C.2
-
65
-
-
1542467646
-
Integrin alpha2beta1 inhibits Fasmediated apoptosis in T lymphocytes by protein phosphatase 2Adependent activation of the MAPK/ERK pathway
-
Gendron S, Couture J, Aoudjit F. Integrin alpha2beta1 inhibits Fasmediated apoptosis in T lymphocytes by protein phosphatase 2Adependent activation of the MAPK/ERK pathway. J Biol Chem 2003;278:48633-43.
-
(2003)
J Biol Chem
, vol.278
, pp. 48633-48643
-
-
Gendron, S.1
Couture, J.2
Aoudjit, F.3
-
66
-
-
84902548039
-
ZIP1 and zinc inhibits fluorideinduced apoptosis in MC3T3-E1 cells
-
Xu S, Yang Y, Han S, Wu Z. ZIP1 and zinc inhibits fluorideinduced apoptosis in MC3T3-E1 cells. Biol Trace Elem Res 2014; 159:399-409.
-
(2014)
Biol Trace Elem Res
, vol.159
, pp. 399-409
-
-
Xu, S.1
Yang, Y.2
Han, S.3
Wu, Z.4
-
67
-
-
84942237817
-
Davunetide (NAP) protects the retina against early diabetic injury by reducing apoptotic death
-
Scuderi S, D'Amico AG, Castorina A, et al. Davunetide (NAP) protects the retina against early diabetic injury by reducing apoptotic death. J Mol Neurosci 2014;54:395-404.
-
(2014)
J Mol Neurosci
, vol.54
, pp. 395-404
-
-
Scuderi, S.1
D'Amico, A.G.2
Castorina, A.3
-
68
-
-
84881474061
-
Chlamydia inhibit host cell apoptosis by inducing Bag-1 via the MAPK/ERK survival pathway
-
Kun D, Xiang-Lin C, Ming Z, Qi L. Chlamydia inhibit host cell apoptosis by inducing Bag-1 via the MAPK/ERK survival pathway. Apoptosis 2013;18:1083-92.
-
(2013)
Apoptosis
, vol.18
, pp. 1083-1092
-
-
Kun, D.1
Xiang-Lin, C.2
Ming, Z.3
Qi, L.4
-
69
-
-
84874976764
-
ZnT7 can protect MC3T3-E1 cells from oxidative stress-induced apoptosis via PI3K/Akt and MAPK/ERK signaling pathways
-
Liang D, Xiang L, Yang M, et al. ZnT7 can protect MC3T3-E1 cells from oxidative stress-induced apoptosis via PI3K/Akt and MAPK/ERK signaling pathways. Cell Signal 2013;25:1126-35.
-
(2013)
Cell Signal
, vol.25
, pp. 1126-1135
-
-
Liang, D.1
Xiang, L.2
Yang, M.3
-
70
-
-
84878346467
-
Vaspin attenuates the apoptosis of human osteoblasts through ERK signaling pathway
-
Zhu X, Jiang Y, Shan PF, et al. Vaspin attenuates the apoptosis of human osteoblasts through ERK signaling pathway. Amino Acids 2013;44:961-8.
-
(2013)
Amino Acids
, vol.44
, pp. 961-968
-
-
Zhu, X.1
Jiang, Y.2
Shan, P.F.3
-
71
-
-
84864473848
-
Vascular smooth muscle cell apoptosis promotes transplant arteriosclerosis through inducing the production of SDF-1alpha
-
Li J, Liu S, Li W, et al. Vascular smooth muscle cell apoptosis promotes transplant arteriosclerosis through inducing the production of SDF-1alpha. Am J Transplant 2012;12:2029-43.
-
(2012)
Am J Transplant
, vol.12
, pp. 2029-2043
-
-
Li, J.1
Liu, S.2
Li, W.3
-
72
-
-
79951826319
-
Injury-induced activation of the MAPK/CREB pathway triggers apoptosis-induced compensatory proliferation in hydra head regeneration
-
Chera S, Ghila L, Wenger Y, Galliot B. Injury-induced activation of the MAPK/CREB pathway triggers apoptosis-induced compensatory proliferation in hydra head regeneration. Dev Growth Differ 2011;53:186-201.
-
(2011)
Dev Growth Differ
, vol.53
, pp. 186-201
-
-
Chera, S.1
Ghila, L.2
Wenger, Y.3
Galliot, B.4
-
73
-
-
67649220227
-
NaF activates MAPKs and induces apoptosis in odontoblast-like cells
-
Karube H, Nishitai G, Inageda K, et al. NaF activates MAPKs and induces apoptosis in odontoblast-like cells. J Dent Res 2009;88: 461-5.
-
(2009)
J Dent Res
, vol.88
, pp. 461-465
-
-
Karube, H.1
Nishitai, G.2
Inageda, K.3
-
74
-
-
67349278470
-
Beta-hydroxy-betamethylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways
-
Kornasio R, Riederer I, Butler-Browne G, et al. Beta-hydroxy-betamethylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways. Biochim Biophys Acta 2009;1793:755-63.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 755-763
-
-
Kornasio, R.1
Riederer, I.2
Butler-Browne, G.3
-
75
-
-
34548103173
-
Cyclosporine A induces titin expression via MAPK/ERK signalling and improves proliferative and invasive potential of human trophoblast cells
-
Du MR, Zhou WH, Yan FT, et al. Cyclosporine A induces titin expression via MAPK/ERK signalling and improves proliferative and invasive potential of human trophoblast cells. Hum Reprod 2007;22:2528-37.
-
(2007)
Hum Reprod
, vol.22
, pp. 2528-2537
-
-
Du, M.R.1
Zhou, W.H.2
Yan, F.T.3
-
76
-
-
0037099711
-
The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway
-
Sanna B, Debidda M, Pintus G, et al. The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway. Arch Biochem Biophys 2002;403:209-18.
-
(2002)
Arch Biochem Biophys
, vol.403
, pp. 209-218
-
-
Sanna, B.1
Debidda, M.2
Pintus, G.3
-
77
-
-
0033778471
-
Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells
-
Pavlovic D, Andersen NA, Mandrup-Poulsen T, Eizirik DL. Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells. Eur Cytokine Netw 2000;11:267-74.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 267-274
-
-
Pavlovic, D.1
Andersen, N.A.2
Mandrup-Poulsen, T.3
Eizirik, D.L.4
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