-
1
-
-
34948848556
-
Mirk/Dyrk1B in cancer
-
10.1002/jcb.21451, 17583556
-
Friedman E. Mirk/Dyrk1B in cancer. J Cell Biochem 2007, 102:274-279. 10.1002/jcb.21451, 17583556.
-
(2007)
J Cell Biochem
, vol.102
, pp. 274-279
-
-
Friedman, E.1
-
2
-
-
0142071703
-
Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation
-
10.1074/jbc.M306780200, 12902328
-
Deng X, Ewton DZ, Pawlikowski B, Maimone M, Friedman E. Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation. J Biol Chem 2003, 278:41347-41354. 10.1074/jbc.M306780200, 12902328.
-
(2003)
J Biol Chem
, vol.278
, pp. 41347-41354
-
-
Deng, X.1
Ewton, D.Z.2
Pawlikowski, B.3
Maimone, M.4
Friedman, E.5
-
3
-
-
2542489078
-
The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase
-
10.1074/jbc.M400479200, 15010468
-
Deng X, Mercer SE, Shah S, Ewton DZ, Friedman E. The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase. J Biol Chem 2004, 279:22498-22504. 10.1074/jbc.M400479200, 15010468.
-
(2004)
J Biol Chem
, vol.279
, pp. 22498-22504
-
-
Deng, X.1
Mercer, S.E.2
Shah, S.3
Ewton, D.Z.4
Friedman, E.5
-
4
-
-
3042684281
-
Mirk/dyrk1B kinase destabilizes cyclin D1 by phosphorylation at threonine 288
-
10.1074/jbc.M403042200, 15075324
-
Zou Y, Ewton DZ, Deng X, Mercer SE, Friedman E. Mirk/dyrk1B kinase destabilizes cyclin D1 by phosphorylation at threonine 288. J Biol Chem 2004, 279:27790-27798. 10.1074/jbc.M403042200, 15075324.
-
(2004)
J Biol Chem
, vol.279
, pp. 27790-27798
-
-
Zou, Y.1
Ewton, D.Z.2
Deng, X.3
Mercer, S.E.4
Friedman, E.5
-
5
-
-
79961121875
-
Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/Rb2
-
10.1002/ijc.25692, 20857490
-
Hu J, Nakhla H, Friedman E. Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/Rb2. Int J Cancer 2011, 129:307-318. 10.1002/ijc.25692, 20857490.
-
(2011)
Int J Cancer
, vol.129
, pp. 307-318
-
-
Hu, J.1
Nakhla, H.2
Friedman, E.3
-
6
-
-
69249110053
-
Mirk regulates the exit of colon cancer cells from quiescence
-
10.1074/jbc.M109.035519, 2755699, 19542220
-
Jin K, Ewton DZ, Park S, Hu J, Friedman E. Mirk regulates the exit of colon cancer cells from quiescence. J Biol Chem 2009, 284:22916-22925. 10.1074/jbc.M109.035519, 2755699, 19542220.
-
(2009)
J Biol Chem
, vol.284
, pp. 22916-22925
-
-
Jin, K.1
Ewton, D.Z.2
Park, S.3
Hu, J.4
Friedman, E.5
-
7
-
-
65949118505
-
Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species
-
10.1158/0008-5472.CAN-08-2903, 2669831, 19351855
-
Deng X, Ewton DZ, Friedman E. Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species. Cancer Res 2009, 69:3317-3324. 10.1158/0008-5472.CAN-08-2903, 2669831, 19351855.
-
(2009)
Cancer Res
, vol.69
, pp. 3317-3324
-
-
Deng, X.1
Ewton, D.Z.2
Friedman, E.3
-
8
-
-
41349099104
-
Cancer statistics, 2008
-
10.3322/CA.2007.0010, 18287387
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ. Cancer statistics, 2008. CA Cancer J Clin 2008, 58:71-96. 10.3322/CA.2007.0010, 18287387.
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
9
-
-
84863338334
-
The involvement of FoxO in cell survival and chemosensitivity mediated by Mirk/Dyrk1B in ovarian cancer
-
Gao J, Yang X, Yin P, Hu W, Liao H, Miao Z, Pan C, Li N. The involvement of FoxO in cell survival and chemosensitivity mediated by Mirk/Dyrk1B in ovarian cancer. Int J Oncol 2012, 40:1203-1209.
-
(2012)
Int J Oncol
, vol.40
, pp. 1203-1209
-
-
Gao, J.1
Yang, X.2
Yin, P.3
Hu, W.4
Liao, H.5
Miao, Z.6
Pan, C.7
Li, N.8
-
10
-
-
70350316226
-
Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells
-
10.4161/cbt.8.17.9322, 19633423
-
Gao J, Zheng Z, Rawal B, Schell MJ, Bepler G, Haura EB. Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells. Cancer Biol Ther 2009, 8:1671-1679. 10.4161/cbt.8.17.9322, 19633423.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1671-1679
-
-
Gao, J.1
Zheng, Z.2
Rawal, B.3
Schell, M.J.4
Bepler, G.5
Haura, E.B.6
-
11
-
-
33646247855
-
The kinase Mirk/Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma
-
10.1158/0008-5472.CAN-05-3089, 16618736
-
Deng X, Ewton DZ, Li S, Naqvi A, Mercer SE, Landas S, Friedman E. The kinase Mirk/Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma. Cancer Res 2006, 66:4149-4158. 10.1158/0008-5472.CAN-05-3089, 16618736.
-
(2006)
Cancer Res
, vol.66
, pp. 4149-4158
-
-
Deng, X.1
Ewton, D.Z.2
Li, S.3
Naqvi, A.4
Mercer, S.E.5
Landas, S.6
Friedman, E.7
-
12
-
-
77950897711
-
The kinase Mirk is a potential therapeutic target in osteosarcoma
-
Yang C, Ji D, Weinstein EJ, Choy E, Hornicek FJ, Wood KB, Liu X, Mankin H, Duan Z. The kinase Mirk is a potential therapeutic target in osteosarcoma. Carcinogenesis 2012, 31:552-558.
-
(2012)
Carcinogenesis
, vol.31
, pp. 552-558
-
-
Yang, C.1
Ji, D.2
Weinstein, E.J.3
Choy, E.4
Hornicek, F.J.5
Wood, K.B.6
Liu, X.7
Mankin, H.8
Duan, Z.9
-
13
-
-
79959367264
-
Depleting mirk kinase increases cisplatin toxicity in ovarian cancer cells
-
Hu J, Friedman E. Depleting mirk kinase increases cisplatin toxicity in ovarian cancer cells. Genes Cancer 2012, 1:803-811.
-
(2012)
Genes Cancer
, vol.1
, pp. 803-811
-
-
Hu, J.1
Friedman, E.2
-
14
-
-
11044230487
-
Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells
-
10.1111/j.1349-7006.2004.tb02200.x, 15546508
-
Gao J, Niwa K, Sun W, Takemura M, Lian Z, Onogi K, Seishima M, Mori H, Tamaya T. Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells. Cancer Sci 2004, 95:901-907. 10.1111/j.1349-7006.2004.tb02200.x, 15546508.
-
(2004)
Cancer Sci
, vol.95
, pp. 901-907
-
-
Gao, J.1
Niwa, K.2
Sun, W.3
Takemura, M.4
Lian, Z.5
Onogi, K.6
Seishima, M.7
Mori, H.8
Tamaya, T.9
-
15
-
-
0037699512
-
Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells
-
10.1038/sj.onc.1206479, 12833138
-
Song L, Turkson J, Karras JG, Jove R, Haura EB. Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells. Oncogene 2003, 22:4150-4165. 10.1038/sj.onc.1206479, 12833138.
-
(2003)
Oncogene
, vol.22
, pp. 4150-4165
-
-
Song, L.1
Turkson, J.2
Karras, J.G.3
Jove, R.4
Haura, E.B.5
-
16
-
-
36849065315
-
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
-
10.1016/j.cell.2007.11.025, 18083107
-
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007, 131:1190-1203. 10.1016/j.cell.2007.11.025, 18083107.
-
(2007)
Cell
, vol.131
, pp. 1190-1203
-
-
Rikova, K.1
Guo, A.2
Zeng, Q.3
Possemato, A.4
Yu, J.5
Haack, H.6
Nardone, J.7
Lee, K.8
Reeves, C.9
Li, Y.10
Hu, Y.11
Tan, Z.12
Stokes, M.13
Sullivan, L.14
Mitchell, J.15
Wetzel, R.16
Macneill, J.17
Ren, J.M.18
Yuan, J.19
Bakalarski, C.E.20
Villen, J.21
Kornhauser, J.M.22
Smith, B.23
Li, D.24
Zhou, X.25
Gygi, S.P.26
Gu, T.L.27
Polakiewicz, R.D.28
Rush, J.29
Comb, M.J.30
more..
-
17
-
-
4544320211
-
Regulation of Dyrk1A kinase activity by 14-3-3
-
10.1016/j.bbrc.2004.08.102, 15369779
-
Kim D, Won J, Shin DW, Kang J, Kim YJ, Choi SY, Hwang MK, Jeong BW, Kim GS, Joe CO, Chung SH, Song WJ. Regulation of Dyrk1A kinase activity by 14-3-3. Biochem Biophys Res Commun 2004, 323:499-504. 10.1016/j.bbrc.2004.08.102, 15369779.
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 499-504
-
-
Kim, D.1
Won, J.2
Shin, D.W.3
Kang, J.4
Kim, Y.J.5
Choi, S.Y.6
Hwang, M.K.7
Jeong, B.W.8
Kim, G.S.9
Joe, C.O.10
Chung, S.H.11
Song, W.J.12
-
18
-
-
34247210208
-
DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding
-
10.1091/mbc.E06-08-0668, 1838983, 17229891
-
Alvarez M, Altafaj X, Aranda S, de la Luna S. DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding. Mol Biol Cell 2007, 18:1167-1178. 10.1091/mbc.E06-08-0668, 1838983, 17229891.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1167-1178
-
-
Alvarez, M.1
Altafaj, X.2
Aranda, S.3
de la Luna, S.4
-
19
-
-
20444387985
-
Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs
-
10.1016/j.cell.2005.03.034, 15960979
-
Lochhead PA, Sibbet G, Morrice N, Cleghon V. Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs. Cell 2005, 121:925-936. 10.1016/j.cell.2005.03.034, 15960979.
-
(2005)
Cell
, vol.121
, pp. 925-936
-
-
Lochhead, P.A.1
Sibbet, G.2
Morrice, N.3
Cleghon, V.4
-
20
-
-
0034235542
-
Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells
-
Lee K, Deng X, Friedman E. Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells. Cancer Res 2000, 60:3631-3637.
-
(2000)
Cancer Res
, vol.60
, pp. 3631-3637
-
-
Lee, K.1
Deng, X.2
Friedman, E.3
-
21
-
-
0037067736
-
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha
-
10.1074/jbc.M203257200, 11980910
-
Lim S, Jin K, Friedman E. Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha. J Biol Chem 2002, 277:25040-25046. 10.1074/jbc.M203257200, 11980910.
-
(2002)
J Biol Chem
, vol.277
, pp. 25040-25046
-
-
Lim, S.1
Jin, K.2
Friedman, E.3
|