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Volumn 46, Issue 16, 2010, Pages 2996-3006

STAT3 activation induced by Epstein-Barr virus latent membrane protein1 causes vascular endothelial growth factor expression and cellular invasiveness via JAK3 and ERK signaling

Author keywords

Epstein Barr virus; Extracellular signal regulated kinase 1 2; Invasion ability; Janus kinase 3; Latent membrane protein 1; Nasopharyngeal carcinoma; PD98059; Signal transducer and activator of transcription 3; Vascular endothelial growth factor; WHI P131

Indexed keywords

JANUS KINASE 3; LATENT MEMBRANE PROTEIN 1; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; STAT3 PROTEIN; VASCULOTROPIN;

EID: 78049295535     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.07.008     Document Type: Article
Times cited : (81)

References (60)
  • 1
    • 2442540470 scopus 로고    scopus 로고
    • Focus on nasopharyngeal carcinoma
    • K.W. Lo, K.F. To, and D.P. Huang Focus on nasopharyngeal carcinoma Cancer Cell 5 2004 423 428
    • (2004) Cancer Cell , vol.5 , pp. 423-428
    • Lo, K.W.1    To, K.F.2    Huang, D.P.3
  • 2
    • 0036435166 scopus 로고    scopus 로고
    • Epstein-Barr virus in the pathogenesis of NPC
    • N. Raab-Traub Epstein-Barr virus in the pathogenesis of NPC Semin Cancer Biol 12 2002 431 441
    • (2002) Semin Cancer Biol , vol.12 , pp. 431-441
    • Raab-Traub, N.1
  • 3
    • 0026700212 scopus 로고
    • Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-kappa B activity
    • M.L. Hammarskjold, and M.C. Simurda Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-kappa B activity J Virol 66 1992 6496 6501
    • (1992) J Virol , vol.66 , pp. 6496-6501
    • Hammarskjold, M.L.1    Simurda, M.C.2
  • 4
    • 0030728946 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade
    • A. Kieser, E. Kilger, and O. Gires Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade EMBO J 16 1997 6478 6485
    • (1997) EMBO J , vol.16 , pp. 6478-6485
    • Kieser, A.1    Kilger, E.2    Gires, O.3
  • 5
    • 0037423201 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling
    • C.W. Dawson, G. Tramountanis, A.G. Eliopoulos, and L.S. Young Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling J Biol Chem 278 2003 3694 3704
    • (2003) J Biol Chem , vol.278 , pp. 3694-3704
    • Dawson, C.W.1    Tramountanis, G.2    Eliopoulos, A.G.3    Young, L.S.4
  • 6
    • 27144542052 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 CTAR1 mediates rodent and human fibroblast transformation through activation of PI3K
    • B.A. Mainou, D.N. Everly Jr., and N. Raab-Traub Epstein-Barr virus latent membrane protein 1 CTAR1 mediates rodent and human fibroblast transformation through activation of PI3K Oncogene 24 2005 6917 6924
    • (2005) Oncogene , vol.24 , pp. 6917-6924
    • Mainou, B.A.1    Everly, Jr.D.N.2    Raab-Traub, N.3
  • 7
    • 34547965826 scopus 로고    scopus 로고
    • Latent membrane protein 1 of Epstein-Barr virus regulates p53 phosphorylation through MAP kinases
    • L. Li, L. Guo, and Y. Tao Latent membrane protein 1 of Epstein-Barr virus regulates p53 phosphorylation through MAP kinases Cancer Lett 255 2007 219 231
    • (2007) Cancer Lett , vol.255 , pp. 219-231
    • Li, L.1    Guo, L.2    Tao, Y.3
  • 8
    • 0032484473 scopus 로고    scopus 로고
    • Activation of a ras-MAPK-dependent pathway by Epstein-Barr virus latent membrane protein 1 is essential for cellular transformation
    • M.L. Roberts, and N.R. Cooper Activation of a ras-MAPK-dependent pathway by Epstein-Barr virus latent membrane protein 1 is essential for cellular transformation Virology 240 1998 93 99
    • (1998) Virology , vol.240 , pp. 93-99
    • Roberts, M.L.1    Cooper, N.R.2
  • 9
    • 41149159605 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded LMP1 regulates epithelial cell motility and invasion via the ERK-MAPK pathway
    • C.W. Dawson, L. Laverick, M.A. Morris, G. Tramoutanis, and L.S. Young Epstein-Barr virus-encoded LMP1 regulates epithelial cell motility and invasion via the ERK-MAPK pathway J Virol 82 2008 3654 3664
    • (2008) J Virol , vol.82 , pp. 3654-3664
    • Dawson, C.W.1    Laverick, L.2    Morris, M.A.3    Tramoutanis, G.4    Young, L.S.5
  • 10
    • 0032487999 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein-1 (LMP1) signalling is distinct from CD40 and involves physical cooperation of its two C-terminus functional regions
    • J.E. Floettmann, A.G. Eliopoulos, M. Jones, L.S. Young, and M. Rowe Epstein-Barr virus latent membrane protein-1 (LMP1) signalling is distinct from CD40 and involves physical cooperation of its two C-terminus functional regions Oncogene 17 1998 2383 2392
    • (1998) Oncogene , vol.17 , pp. 2383-2392
    • Floettmann, J.E.1    Eliopoulos, A.G.2    Jones, M.3    Young, L.S.4    Rowe, M.5
  • 11
    • 0034847766 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways
    • C.A. Fielding, K. Sandvej, and A. Mehl Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways J Virol 75 2001 9129 9141
    • (2001) J Virol , vol.75 , pp. 9129-9141
    • Fielding, C.A.1    Sandvej, K.2    Mehl, A.3
  • 12
    • 0033523115 scopus 로고    scopus 로고
    • Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production
    • A.G. Eliopoulos, N.J. Gallagher, S.M. Blake, C.W. Dawson, and L.S. Young Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production J Biol Chem 274 1999 16085 16096
    • (1999) J Biol Chem , vol.274 , pp. 16085-16096
    • Eliopoulos, A.G.1    Gallagher, N.J.2    Blake, S.M.3    Dawson, C.W.4    Young, L.S.5
  • 13
    • 0033153426 scopus 로고    scopus 로고
    • Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins
    • O. Gires, F. Kohlhuber, and E. Kilger Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins EMBO J 18 1999 3064 3073
    • (1999) EMBO J , vol.18 , pp. 3064-3073
    • Gires, O.1    Kohlhuber, F.2    Kilger, E.3
  • 14
    • 0029051898 scopus 로고
    • Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma
    • R. Pathmanathan, U. Prasad, R. Sadler, K. Flynn, and N. Raab-Traub Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma N Engl J Med 333 1995 693 698
    • (1995) N Engl J Med , vol.333 , pp. 693-698
    • Pathmanathan, R.1    Prasad, U.2    Sadler, R.3    Flynn, K.4    Raab-Traub, N.5
  • 16
    • 0036063344 scopus 로고    scopus 로고
    • Promotion of metastasis in nasopharyngeal carcinoma by Epstein-Barr virus latent membrane protein-1
    • T. Yoshizaki Promotion of metastasis in nasopharyngeal carcinoma by Epstein-Barr virus latent membrane protein-1 Histol Histopathol 17 2002 845 850
    • (2002) Histol Histopathol , vol.17 , pp. 845-850
    • Yoshizaki, T.1
  • 17
    • 0034663173 scopus 로고    scopus 로고
    • Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma
    • T. Horikawa, T. Yoshizaki, T.S. Sheen, S.Y. Lee, and M. Furukawa Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma Cancer 89 2000 715 723
    • (2000) Cancer , vol.89 , pp. 715-723
    • Horikawa, T.1    Yoshizaki, T.2    Sheen, T.S.3    Lee, S.Y.4    Furukawa, M.5
  • 18
    • 0029011016 scopus 로고
    • Differences in the growth pattern and clinical course of EBV-LMP1 expressing and non-expressing nasopharyngeal carcinomas
    • L.F. Hu, F. Chen, and Q.F. Zhen Differences in the growth pattern and clinical course of EBV-LMP1 expressing and non-expressing nasopharyngeal carcinomas Eur J Cancer 31A 1995 658 660
    • (1995) Eur J Cancer , vol.31 , pp. 658-660
    • Hu, L.F.1    Chen, F.2    Zhen, Q.F.3
  • 19
    • 38949131488 scopus 로고    scopus 로고
    • Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma
    • Y.P. Liu, Y.N. Tan, and Z.L. Wang Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma Int J Mol Med 21 2008 153 162
    • (2008) Int J Mol Med , vol.21 , pp. 153-162
    • Liu, Y.P.1    Tan, Y.N.2    Wang, Z.L.3
  • 20
    • 0037378534 scopus 로고    scopus 로고
    • A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus
    • H. Chen, L. Hutt-Fletcher, L. Cao, and S.D. Hayward A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus J Virol 77 2003 4139 4148
    • (2003) J Virol , vol.77 , pp. 4139-4148
    • Chen, H.1    Hutt-Fletcher, L.2    Cao, L.3    Hayward, S.D.4
  • 21
    • 33644773438 scopus 로고    scopus 로고
    • STAT3 as a therapeutic target in head and neck cancer
    • R.J. Leeman, V.W. Lui, and J.R. Grandis STAT3 as a therapeutic target in head and neck cancer Expert Opin Biol Ther 6 2006 231 241
    • (2006) Expert Opin Biol Ther , vol.6 , pp. 231-241
    • Leeman, R.J.1    Lui, V.W.2    Grandis, J.R.3
  • 22
    • 77952242739 scopus 로고    scopus 로고
    • Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response
    • B.B. Ma, V.W. Lui, and F.F. Poon Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response Invest New Drugs 28 2010 326 333
    • (2010) Invest New Drugs , vol.28 , pp. 326-333
    • Ma, B.B.1    Lui, V.W.2    Poon, F.F.3
  • 23
    • 0141537121 scopus 로고    scopus 로고
    • Expression of JAK3 in nasopharyngeal carcinoma cell line associated with STAT activation regulated by EB virus encoded protein LMP1
    • Y.N. Tan, Y.G. Tao, and X. Song Expression of JAK3 in nasopharyngeal carcinoma cell line associated with STAT activation regulated by EB virus encoded protein LMP1 Prog Biochem Biophys 30 2003 560 565
    • (2003) Prog Biochem Biophys , vol.30 , pp. 560-565
    • Tan, Y.N.1    Tao, Y.G.2    Song, X.3
  • 24
    • 34548085155 scopus 로고    scopus 로고
    • Role of Epstein-Barr virus encoded latent membrane protein 1 in the carcinogenesis of nasopharyngeal carcinoma
    • H. Zheng, L.L. Li, D.S. Hu, X.Y. Deng, and Y. Cao Role of Epstein-Barr virus encoded latent membrane protein 1 in the carcinogenesis of nasopharyngeal carcinoma Cell Mol Immunol 4 2007 185 196
    • (2007) Cell Mol Immunol , vol.4 , pp. 185-196
    • Zheng, H.1    Li, L.L.2    Hu, D.S.3    Deng, X.Y.4    Cao, Y.5
  • 25
    • 0035917876 scopus 로고    scopus 로고
    • Ser727-dependent transcriptional activation by association of p300 with STAT3 upon IL-6 stimulation
    • J.J. Schuringa, H. Schepers, E. Vellenga, and W. Kruijer Ser727-dependent transcriptional activation by association of p300 with STAT3 upon IL-6 stimulation FEBS Lett 495 2001 71 76
    • (2001) FEBS Lett , vol.495 , pp. 71-76
    • Schuringa, J.J.1    Schepers, H.2    Vellenga, E.3    Kruijer, W.4
  • 26
    • 0037096988 scopus 로고    scopus 로고
    • Biphasic regulation of extracellular-signal-regulated protein kinase by leptin in macrophages: Role in regulating STAT3 Ser727 phosphorylation and DNA binding
    • L. O'Rourke, and P.R. Shepherd Biphasic regulation of extracellular-signal-regulated protein kinase by leptin in macrophages: role in regulating STAT3 Ser727 phosphorylation and DNA binding Biochem J 364 2002 875 879
    • (2002) Biochem J , vol.364 , pp. 875-879
    • O'Rourke, L.1    Shepherd, P.R.2
  • 27
    • 0034722896 scopus 로고    scopus 로고
    • STAT proteins: Novel molecular targets for cancer drug discovery
    • J. Turkson, and R. Jove STAT proteins: novel molecular targets for cancer drug discovery Oncogene 19 2000 6613 6626
    • (2000) Oncogene , vol.19 , pp. 6613-6626
    • Turkson, J.1    Jove, R.2
  • 28
    • 0030772458 scopus 로고    scopus 로고
    • STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation
    • J. Chung, E. Uchida, T.C. Grammer, and J. Blenis STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation Mol Cell Biol 17 1997 6508 6516
    • (1997) Mol Cell Biol , vol.17 , pp. 6508-6516
    • Chung, J.1    Uchida, E.2    Grammer, T.C.3    Blenis, J.4
  • 29
    • 0346101797 scopus 로고    scopus 로고
    • Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism
    • R.K. Lo, H. Cheung, and Y.H. Wong Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism J Biol Chem 278 2003 52154 52165
    • (2003) J Biol Chem , vol.278 , pp. 52154-52165
    • Lo, R.K.1    Cheung, H.2    Wong, Y.H.3
  • 30
    • 85047695527 scopus 로고    scopus 로고
    • Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
    • G. Niu, K.L. Wright, and M. Huang Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis Oncogene 21 2002 2000 2008
    • (2002) Oncogene , vol.21 , pp. 2000-2008
    • Niu, G.1    Wright, K.L.2    Huang, M.3
  • 31
    • 22044447619 scopus 로고    scopus 로고
    • Effect of EBV LMP1 targeted DNAzymes on cell proliferation and apoptosis
    • Z.X. Lu, M. Ye, and G.R. Yan Effect of EBV LMP1 targeted DNAzymes on cell proliferation and apoptosis Cancer Gene Ther 12 2005 647 654
    • (2005) Cancer Gene Ther , vol.12 , pp. 647-654
    • Lu, Z.X.1    Ye, M.2    Yan, G.R.3
  • 32
    • 0029936611 scopus 로고    scopus 로고
    • Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway
    • C. Beadling, J. Ng, J.W. Babbage, and D.A. Cantrell Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway EMBO J 15 1996 1902 1913
    • (1996) EMBO J , vol.15 , pp. 1902-1913
    • Beadling, C.1    Ng, J.2    Babbage, J.W.3    Cantrell, D.A.4
  • 33
    • 0032533504 scopus 로고    scopus 로고
    • Evidence of cisplatin-induced senescent-like growth arrest in nasopharyngeal carcinoma cells
    • X. Wang, S.C. Wong, and J. Pan Evidence of cisplatin-induced senescent-like growth arrest in nasopharyngeal carcinoma cells Cancer Res 58 1998 5019 5022
    • (1998) Cancer Res , vol.58 , pp. 5019-5022
    • Wang, X.1    Wong, S.C.2    Pan, J.3
  • 34
    • 33645472678 scopus 로고    scopus 로고
    • Identification of novel phosphoproteins in signaling pathways triggered by latent membrane protein 1 using functional proteomics technology
    • G. Yan, L. Li, and Y. Tao Identification of novel phosphoproteins in signaling pathways triggered by latent membrane protein 1 using functional proteomics technology Proteomics 6 2006 1810 1821
    • (2006) Proteomics , vol.6 , pp. 1810-1821
    • Yan, G.1    Li, L.2    Tao, Y.3
  • 35
    • 0037112367 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
    • L.B. Mora, R. Buettner, and J. Seigne Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells Cancer Res 62 2002 6659 6666
    • (2002) Cancer Res , vol.62 , pp. 6659-6666
    • Mora, L.B.1    Buettner, R.2    Seigne, J.3
  • 36
    • 20944435271 scopus 로고    scopus 로고
    • Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
    • R. Chiarle, W.J. Simmons, and H. Cai Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target Nat Med 11 2005 623 629
    • (2005) Nat Med , vol.11 , pp. 623-629
    • Chiarle, R.1    Simmons, W.J.2    Cai, H.3
  • 37
    • 4243156987 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines
    • B.E. Barton, J.G. Karras, T.F. Murphy, A. Barton, and H.F. Huang Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: direct STAT3 inhibition induces apoptosis in prostate cancer lines Mol Cancer Ther 3 2004 11 20 (Pubitemid 39193674)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.1 , pp. 11-20
    • Barton, B.E.1    Karras, J.G.2    Murphy, T.F.3    Barton, A.4    Huang, H.F.-S.5
  • 38
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • S.M. Elbashir, J. Harborth, and W. Lendeckel Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3
  • 39
    • 19944381865 scopus 로고    scopus 로고
    • Connexin32 as a tumor suppressor gene in a metastatic renal cell carcinoma cell line
    • E. Fujimoto, H. Sato, and S. Shirai Connexin32 as a tumor suppressor gene in a metastatic renal cell carcinoma cell line Oncogene 24 2005 3684 3690
    • (2005) Oncogene , vol.24 , pp. 3684-3690
    • Fujimoto, E.1    Sato, H.2    Shirai, S.3
  • 40
    • 3042748279 scopus 로고    scopus 로고
    • Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
    • L. Konnikova, M. Kotecki, M.M. Kruger, and B.H. Cochran Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells BMC Cancer 3 2003 23
    • (2003) BMC Cancer , vol.3 , pp. 23
    • Konnikova, L.1    Kotecki, M.2    Kruger, M.M.3    Cochran, B.H.4
  • 41
    • 0035403317 scopus 로고    scopus 로고
    • Induction of c-met proto-oncogene by Epstein-Barr virus latent membrane protein-1 and the correlation with cervical lymph node metastasis of nasopharyngeal carcinoma
    • T. Horikawa, T.S. Sheen, and H. Takeshita Induction of c-Met proto-oncogene by Epstein-Barr virus latent membrane protein-1 and the correlation with cervical lymph node metastasis of nasopharyngeal carcinoma Am J Pathol 159 2001 27 33 (Pubitemid 33704188)
    • (2001) American Journal of Pathology , vol.159 , Issue.1 , pp. 27-33
    • Horikawa, T.1    Sheen, T.-S.2    Takeshita, H.3    Sato, H.4    Furukawa, M.5    Yoshizaki, T.6
  • 42
    • 0034732153 scopus 로고    scopus 로고
    • Transformation of Madin-Darby canine kidney (MDCK) epithelial cells by Epstein-Barr virus latent membrane protein 1 (LMP1) induces expression of Ets1 and invasive growth
    • K.R. Kim, T. Yoshizaki, and H. Miyamori Transformation of Madin-Darby canine kidney (MDCK) epithelial cells by Epstein-Barr virus latent membrane protein 1 (LMP1) induces expression of Ets1 and invasive growth Oncogene 19 2000 1764 1771
    • (2000) Oncogene , vol.19 , pp. 1764-1771
    • Kim, K.R.1    Yoshizaki, T.2    Miyamori, H.3
  • 43
    • 33750537081 scopus 로고    scopus 로고
    • EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells
    • S. Kondo, S.Y. Seo, and T. Yoshizaki EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells Cancer Res 66 2006 9870 9877
    • (2006) Cancer Res , vol.66 , pp. 9870-9877
    • Kondo, S.1    Seo, S.Y.2    Yoshizaki, T.3
  • 44
    • 0034192392 scopus 로고    scopus 로고
    • Aspirin inhibits tumor cell invasiveness induced by Epstein-Barr virus latent membrane protein 1 through suppression of matrix metalloproteinase-9 expression
    • S. Murono, T. Yoshizaki, and H. Sato Aspirin inhibits tumor cell invasiveness induced by Epstein-Barr virus latent membrane protein 1 through suppression of matrix metalloproteinase-9 expression Cancer Res 60 2000 2555 2561
    • (2000) Cancer Res , vol.60 , pp. 2555-2561
    • Murono, S.1    Yoshizaki, T.2    Sato, H.3
  • 45
    • 0035811070 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells
    • S. Murono, H. Inoue, and T. Tanabe Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells Proc Natl Acad Sci USA 98 2001 6905 6910
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6905-6910
    • Murono, S.1    Inoue, H.2    Tanabe, T.3
  • 46
    • 0033031799 scopus 로고    scopus 로고
    • Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2
    • H. Takeshita, T. Yoshizaki, and W.E. Miller Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2 J Virol 73 1999 5548 5555
    • (1999) J Virol , vol.73 , pp. 5548-5555
    • Takeshita, H.1    Yoshizaki, T.2    Miller, W.E.3
  • 47
    • 0036829132 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces and causes release of fibroblast growth factor-2
    • N. Wakisaka, S. Murono, T. Yoshizaki, M. Furukawa, and J.S. Pagano Epstein-Barr virus latent membrane protein 1 induces and causes release of fibroblast growth factor-2 Cancer Res 62 2002 6337 6344
    • (2002) Cancer Res , vol.62 , pp. 6337-6344
    • Wakisaka, N.1    Murono, S.2    Yoshizaki, T.3    Furukawa, M.4    Pagano, J.S.5
  • 48
    • 2542443138 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha
    • N. Wakisaka, S. Kondo, and T. Yoshizaki Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha Mol Cell Biol 24 2004 5223 5234
    • (2004) Mol Cell Biol , vol.24 , pp. 5223-5234
    • Wakisaka, N.1    Kondo, S.2    Yoshizaki, T.3
  • 49
    • 0032584221 scopus 로고    scopus 로고
    • The expression of matrix metalloproteinase 9 is enhanced by Epstein-Barr virus latent membrane protein 1
    • T. Yoshizaki, H. Sato, M. Furukawa, and J.S. Pagano The expression of matrix metalloproteinase 9 is enhanced by Epstein-Barr virus latent membrane protein 1 Proc Natl Acad Sci USA 95 1998 3621 3626
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3621-3626
    • Yoshizaki, T.1    Sato, H.2    Furukawa, M.3    Pagano, J.S.4
  • 50
    • 18644368754 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces the matrix metalloproteinase-1 promoter via an Ets binding site formed by a single nucleotide polymorphism: Enhanced susceptibility to nasopharyngeal carcinoma
    • S. Kondo, N. Wakisaka, and M.J. Schell Epstein-Barr virus latent membrane protein 1 induces the matrix metalloproteinase-1 promoter via an Ets binding site formed by a single nucleotide polymorphism: enhanced susceptibility to nasopharyngeal carcinoma Int J Cancer 115 2005 368 376
    • (2005) Int J Cancer , vol.115 , pp. 368-376
    • Kondo, S.1    Wakisaka, N.2    Schell, M.J.3
  • 51
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer - New molecular targets come of age
    • H. Yu, and R. Jove The STATs of cancer - new molecular targets come of age Nat Rev Cancer 4 2004 97 105
    • (2004) Nat Rev Cancer , vol.4 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 52
    • 2542421748 scopus 로고    scopus 로고
    • Multiple signal transducers and activators of transcription are induced by EBV LMP-1
    • L. Zhang, K. Hong, J. Zhang, and J.S. Pagano Multiple signal transducers and activators of transcription are induced by EBV LMP-1 Virology 323 2004 141 152
    • (2004) Virology , vol.323 , pp. 141-152
    • Zhang, L.1    Hong, K.2    Zhang, J.3    Pagano, J.S.4
  • 53
    • 33846841171 scopus 로고    scopus 로고
    • MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling
    • S. Kondo, T. Yoshizaki, and N. Wakisaka MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling J Virol 81 2007 1554 1562
    • (2007) J Virol , vol.81 , pp. 1554-1562
    • Kondo, S.1    Yoshizaki, T.2    Wakisaka, N.3
  • 54
    • 33646338489 scopus 로고    scopus 로고
    • Epstein-Barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cells
    • A.K. Lo, K.W. Lo, and S.W. Tsao Epstein-Barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cells Neoplasia 8 2006 173 180
    • (2006) Neoplasia , vol.8 , pp. 173-180
    • Lo, A.K.1    Lo, K.W.2    Tsao, S.W.3
  • 55
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Z. Wen, Z. Zhong, and J.E. Darnell Jr Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation Cell 82 1995 241 250
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell, Jr.J.E.3
  • 56
    • 4243202803 scopus 로고    scopus 로고
    • Regulation of human VEGF expression by latent membrane protein 1 encoded by EB virus via STAT3 in nasopharyngeal carcinoma cell line
    • Y.N. Tan, Y.G. Tao, and L.L. Li Regulation of human VEGF expression by latent membrane protein 1 encoded by EB virus via STAT3 in nasopharyngeal carcinoma cell line Prog Biochem Biophys 31 2004 427 431
    • (2004) Prog Biochem Biophys , vol.31 , pp. 427-431
    • Tan, Y.N.1    Tao, Y.G.2    Li, L.L.3
  • 58
    • 64949141535 scopus 로고    scopus 로고
    • Phosphorylated ezrin is associated with EBV latent membrane protein 1 in nasopharyngeal carcinoma and induces cell migration
    • K. Endo, S. Kondo, and J. Shackleford Phosphorylated ezrin is associated with EBV latent membrane protein 1 in nasopharyngeal carcinoma and induces cell migration Oncogene 28 2009 1725 1735
    • (2009) Oncogene , vol.28 , pp. 1725-1735
    • Endo, K.1    Kondo, S.2    Shackleford, J.3
  • 59
    • 69449087653 scopus 로고    scopus 로고
    • Decoy receptor 3, upregulated by Epstein-Barr virus latent membrane protein 1, enhances nasopharyngeal carcinoma cell migration and invasion
    • C.H. Ho, C.L. Chen, W.Y. Li, and C.J. Chen Decoy receptor 3, upregulated by Epstein-Barr virus latent membrane protein 1, enhances nasopharyngeal carcinoma cell migration and invasion Carcinogenesis 30 2009 1443 1451
    • (2009) Carcinogenesis , vol.30 , pp. 1443-1451
    • Ho, C.H.1    Chen, C.L.2    Li, W.Y.3    Chen, C.J.4
  • 60
    • 33947196379 scopus 로고    scopus 로고
    • Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma
    • T. Horikawa, J. Yang, and S. Kondo Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma Cancer Res 67 2007 1970 1978
    • (2007) Cancer Res , vol.67 , pp. 1970-1978
    • Horikawa, T.1    Yang, J.2    Kondo, S.3


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