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Volumn 8, Issue 8, 2013, Pages

Oleanolic Acid Suppresses Migration and Invasion of Malignant Glioma Cells by Inactivating MAPK/ERK Signaling Pathway

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; OLEANOLIC ACID; TRANSCRIPTION FACTOR TWIST; UVOMORULIN; VIMENTIN;

EID: 84882708117     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072079     Document Type: Article
Times cited : (84)

References (27)
  • 2
    • 57349160348 scopus 로고    scopus 로고
    • Exploring multi-targeting strategies for the treatment of gliomas
    • Omuro AM, (2008) Exploring multi-targeting strategies for the treatment of gliomas. Curr Opin Investig Drugs 9: 1287-1295.
    • (2008) Curr Opin Investig Drugs , vol.9 , pp. 1287-1295
    • Omuro, A.M.1
  • 3
    • 61449123217 scopus 로고    scopus 로고
    • Rho/ROCK and MAPK signaling pathways are involved in glioblastoma cell migration and proliferation
    • Zohrabian VM, Forzani B, Chau Z, Murali R, Jhanwar-Uniyal M, (2009) Rho/ROCK and MAPK signaling pathways are involved in glioblastoma cell migration and proliferation. Anticancer Res 29: 119-123.
    • (2009) Anticancer Res , vol.29 , pp. 119-123
    • Zohrabian, V.M.1    Forzani, B.2    Chau, Z.3    Murali, R.4    Jhanwar-Uniyal, M.5
  • 4
    • 34047270254 scopus 로고    scopus 로고
    • An imbalance between Smad and MAPK pathways is responsible for TGF-beta tumor promoting effects in high-grade gliomas
    • Nickl-Jockschat T, Arslan F, Doerfelt A, Bogdahn U, Bosserhoff A, et al. (2007) An imbalance between Smad and MAPK pathways is responsible for TGF-beta tumor promoting effects in high-grade gliomas. Int J Oncol 30: 499-507.
    • (2007) Int J Oncol , vol.30 , pp. 499-507
    • Nickl-Jockschat, T.1    Arslan, F.2    Doerfelt, A.3    Bogdahn, U.4    Bosserhoff, A.5
  • 5
    • 33747879766 scopus 로고    scopus 로고
    • Glial cell-derived neurotrophic factor (GDNF) promotes low-grade Hs683 glioma cell migration through JNK, ERK-1/2 and p38 MAPK signaling pathways
    • Song H, Moon A, (2006) Glial cell-derived neurotrophic factor (GDNF) promotes low-grade Hs683 glioma cell migration through JNK, ERK-1/2 and p38 MAPK signaling pathways. Neurosci Res 56: 29-38.
    • (2006) Neurosci Res , vol.56 , pp. 29-38
    • Song, H.1    Moon, A.2
  • 6
    • 67649392329 scopus 로고    scopus 로고
    • Anesthetic pentobarbital inhibits proliferation and migration of malignant glioma cells
    • Xie J, Li Y, Huang Y, Qiu P, Shu M, et al. (2009) Anesthetic pentobarbital inhibits proliferation and migration of malignant glioma cells. Cancer Lett 282: 35-42.
    • (2009) Cancer Lett , vol.282 , pp. 35-42
    • Xie, J.1    Li, Y.2    Huang, Y.3    Qiu, P.4    Shu, M.5
  • 7
    • 35348993755 scopus 로고    scopus 로고
    • Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells
    • Kim SY, Kim DH, Han SJ, Hyun JW, Kim HS, (2007) Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells. Biochem Pharmacol 74: 1642-1651.
    • (2007) Biochem Pharmacol , vol.74 , pp. 1642-1651
    • Kim, S.Y.1    Kim, D.H.2    Han, S.J.3    Hyun, J.W.4    Kim, H.S.5
  • 8
    • 75749121314 scopus 로고    scopus 로고
    • Marchantin C: a potential anti-invasion agent in glioma cells
    • Shen J, Li G, Liu Q, He Q, Gu J, et al. (2010) Marchantin C: a potential anti-invasion agent in glioma cells. Cancer Biol Ther 9: 33-39.
    • (2010) Cancer Biol Ther , vol.9 , pp. 33-39
    • Shen, J.1    Li, G.2    Liu, Q.3    He, Q.4    Gu, J.5
  • 9
    • 78649804159 scopus 로고    scopus 로고
    • PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling
    • Thomas SL, Alam R, Lemke N, Schultz LR, Gutierrez JA, et al. (2010) PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling. Neuro Oncol 12: 941-955.
    • (2010) Neuro Oncol , vol.12 , pp. 941-955
    • Thomas, S.L.1    Alam, R.2    Lemke, N.3    Schultz, L.R.4    Gutierrez, J.A.5
  • 10
    • 80053516019 scopus 로고    scopus 로고
    • Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3
    • Fujiwara Y, Komohara Y, Kudo R, Tsurushima K, Ohnishi K, et al. (2011) Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3. Oncol Rep 26: 1533-1537.
    • (2011) Oncol Rep , vol.26 , pp. 1533-1537
    • Fujiwara, Y.1    Komohara, Y.2    Kudo, R.3    Tsurushima, K.4    Ohnishi, K.5
  • 11
    • 80052715123 scopus 로고    scopus 로고
    • Synthetic triterpenoid cyano enone of methyl boswellate activates intrinsic, extrinsic, and endoplasmic reticulum stress cell death pathways in tumor cell lines
    • Ravanan P, Sano R, Talwar P, Ogasawara S, Matsuzawa S, et al. (2011) Synthetic triterpenoid cyano enone of methyl boswellate activates intrinsic, extrinsic, and endoplasmic reticulum stress cell death pathways in tumor cell lines. Mol Cancer Ther 10: 1635-1643.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1635-1643
    • Ravanan, P.1    Sano, R.2    Talwar, P.3    Ogasawara, S.4    Matsuzawa, S.5
  • 12
    • 67650109645 scopus 로고    scopus 로고
    • Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation
    • Martin R, Ibeas E, Carvalho-Tavares J, Hernandez M, Ruiz-Gutierrez V, et al. (2009) Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation. PLoS One 4: e5975.
    • (2009) PLoS One , vol.4
    • Martin, R.1    Ibeas, E.2    Carvalho-Tavares, J.3    Hernandez, M.4    Ruiz-Gutierrez, V.5
  • 13
    • 34248597759 scopus 로고    scopus 로고
    • Acidic triterpenes compromise growth and survival of astrocytoma cell lines by regulating reactive oxygen species accumulation
    • Martin R, Carvalho-Tavares J, Ibeas E, Hernandez M, Ruiz-Gutierrez V, et al. (2007) Acidic triterpenes compromise growth and survival of astrocytoma cell lines by regulating reactive oxygen species accumulation. Cancer Res 67: 3741-3751.
    • (2007) Cancer Res , vol.67 , pp. 3741-3751
    • Martin, R.1    Carvalho-Tavares, J.2    Ibeas, E.3    Hernandez, M.4    Ruiz-Gutierrez, V.5
  • 14
    • 34547621658 scopus 로고    scopus 로고
    • Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling
    • Gao X, Deeb D, Jiang H, Liu Y, Dulchavsky SA, et al. (2007) Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling. J Neurooncol 84: 147-157.
    • (2007) J Neurooncol , vol.84 , pp. 147-157
    • Gao, X.1    Deeb, D.2    Jiang, H.3    Liu, Y.4    Dulchavsky, S.A.5
  • 16
    • 79955829428 scopus 로고    scopus 로고
    • CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells
    • Kim EH, Deng CX, Sporn MB, Liby KT, (2011) CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells. Cancer Prev Res (Phila) 4: 425-434.
    • (2011) Cancer Prev Res (Phila) , vol.4 , pp. 425-434
    • Kim, E.H.1    Deng, C.X.2    Sporn, M.B.3    Liby, K.T.4
  • 17
    • 34250666701 scopus 로고    scopus 로고
    • Production and purification of lentiviral vectors
    • Tiscornia G, Singer O, Verma IM, (2006) Production and purification of lentiviral vectors. Nat Protoc 1: 241-245.
    • (2006) Nat Protoc , vol.1 , pp. 241-245
    • Tiscornia, G.1    Singer, O.2    Verma, I.M.3
  • 18
    • 83055199995 scopus 로고    scopus 로고
    • Oleanolic acid initiates apoptosis in non-small cell lung cancer cell lines and reduces metastasis of a B16F10 melanoma model in vivo
    • Lucio KA, Rocha Gda G, Moncao-Ribeiro LC, Fernandes J, Takiya CM, et al. (2011) Oleanolic acid initiates apoptosis in non-small cell lung cancer cell lines and reduces metastasis of a B16F10 melanoma model in vivo. PLoS One 6: e28596.
    • (2011) PLoS One , vol.6
    • Lucio, K.A.1    Rocha Gda, G.2    Moncao-Ribeiro, L.C.3    Fernandes, J.4    Takiya, C.M.5
  • 19
    • 79957484238 scopus 로고    scopus 로고
    • Oleanolic acid derivative Dex-OA has potent anti-tumor and anti-metastatic activity on osteosarcoma cells in vitro and in vivo
    • Hua Y, Zhang Z, Li J, Li Q, Hu S, et al. (2011) Oleanolic acid derivative Dex-OA has potent anti-tumor and anti-metastatic activity on osteosarcoma cells in vitro and in vivo. Invest New Drugs 29: 258-265.
    • (2011) Invest New Drugs , vol.29 , pp. 258-265
    • Hua, Y.1    Zhang, Z.2    Li, J.3    Li, Q.4    Hu, S.5
  • 20
    • 0036771770 scopus 로고    scopus 로고
    • Phosphatidylinositol 3'-kinase and MAPK/ERK kinase 1/2 differentially regulate expression of vascular endothelial growth factor in human malignant astrocytoma cells
    • Woods SA, McGlade CJ, Guha A, (2002) Phosphatidylinositol 3'-kinase and MAPK/ERK kinase 1/2 differentially regulate expression of vascular endothelial growth factor in human malignant astrocytoma cells. Neuro Oncol 4: 242-252.
    • (2002) Neuro Oncol , vol.4 , pp. 242-252
    • Woods, S.A.1    McGlade, C.J.2    Guha, A.3
  • 21
    • 34247869728 scopus 로고    scopus 로고
    • The protein kinase C-eta isoform induces proliferation in glioblastoma cell lines through an ERK/Elk-1 pathway
    • Uht RM, Amos S, Martin PM, Riggan AE, Hussaini IM, (2007) The protein kinase C-eta isoform induces proliferation in glioblastoma cell lines through an ERK/Elk-1 pathway. Oncogene 26: 2885-2893.
    • (2007) Oncogene , vol.26 , pp. 2885-2893
    • Uht, R.M.1    Amos, S.2    Martin, P.M.3    Riggan, A.E.4    Hussaini, I.M.5
  • 22
    • 77956935369 scopus 로고    scopus 로고
    • Overexpression of CD133 promotes the phosphorylation of Erk in U87MG human glioblastoma cells
    • Dong L, Qi N, Ge RM, Cao CL, Lan F, et al. (2010) Overexpression of CD133 promotes the phosphorylation of Erk in U87MG human glioblastoma cells. Neurosci Lett 484: 210-214.
    • (2010) Neurosci Lett , vol.484 , pp. 210-214
    • Dong, L.1    Qi, N.2    Ge, R.M.3    Cao, C.L.4    Lan, F.5
  • 23
    • 80053993059 scopus 로고    scopus 로고
    • PTPIP51, a positive modulator of the MAPK/Erk pathway, is upregulated in glioblastoma and interacts with 14-3-3beta and PTP1B in situ
    • Petri MK, Koch P, Stenzinger A, Kuchelmeister K, Nestler U, et al. (2011) PTPIP51, a positive modulator of the MAPK/Erk pathway, is upregulated in glioblastoma and interacts with 14-3-3beta and PTP1B in situ. Histol Histopathol 26: 1531-1543.
    • (2011) Histol Histopathol , vol.26 , pp. 1531-1543
    • Petri, M.K.1    Koch, P.2    Stenzinger, A.3    Kuchelmeister, K.4    Nestler, U.5
  • 24
    • 79952020999 scopus 로고    scopus 로고
    • Downregulation of uPA/uPAR inhibits intermittent hypoxia-induced epithelial-mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells
    • Gupta R, Chetty C, Bhoopathi P, Lakka S, Mohanam S, et al. (2011) Downregulation of uPA/uPAR inhibits intermittent hypoxia-induced epithelial-mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells. Int J Oncol 38: 733-744.
    • (2011) Int J Oncol , vol.38 , pp. 733-744
    • Gupta, R.1    Chetty, C.2    Bhoopathi, P.3    Lakka, S.4    Mohanam, S.5
  • 25
    • 84861990869 scopus 로고    scopus 로고
    • Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-beta and miR-24: role in epithelial-to-mesenchymal transition
    • Papadimitriou E, Vasilaki E, Vorvis C, Iliopoulos D, Moustakas A, et al. (2012) Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-beta and miR-24: role in epithelial-to-mesenchymal transition. Oncogene.
    • (2012) Oncogene
    • Papadimitriou, E.1    Vasilaki, E.2    Vorvis, C.3    Iliopoulos, D.4    Moustakas, A.5
  • 26
    • 84866330700 scopus 로고    scopus 로고
    • Consumption of high-fat diet induces tumor progression and epithelial-mesenchymal transition of colorectal cancer in a mouse xenograft model
    • Tang FY, Pai MH, Chiang EP (2012) Consumption of high-fat diet induces tumor progression and epithelial-mesenchymal transition of colorectal cancer in a mouse xenograft model. J Nutr Biochem.
    • (2012) J Nutr Biochem
    • Tang, F.Y.1    Pai, M.H.2    Chiang, E.P.3
  • 27
    • 73349109760 scopus 로고    scopus 로고
    • Triterpenoids as new promising anticancer drugs
    • Petronelli A, Pannitteri G, Testa U, (2009) Triterpenoids as new promising anticancer drugs. Anticancer Drugs 20: 880-892.
    • (2009) Anticancer Drugs , vol.20 , pp. 880-892
    • Petronelli, A.1    Pannitteri, G.2    Testa, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.