Icaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways

International Journal of Hematology

Volumn 97, Issue 5, 2013, Pages 617-623

  Li, Qihui ^a   Huai, Lei ^a   Zhang, Cuiping ^a   Wang, Cuicui ^a   Jia, Yujjao ^a   Chen, Yirui ^a   Yu, Pei ^a   Wang, Houcai ^a   Rao, Qing ^a   Wang, Min ^a   Wang, Jianxiang ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

Author keywords

Acute myeloid leukemia; Apoptosis; Icaritin; MAPK ERK; PI3K AKT

Indexed keywords

ANTILEUKEMIC AGENT; CASPASE 3; CASPASE 7; CASPASE 9; ICARITIN; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT MEDICINAL PRODUCT; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL PROLIFERATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; DOSE TIME EFFECT RELATION; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LEUKEMIA CELL LINE; MALE; MONONUCLEAR CELL; ONCOGENE C MYC; PROTEIN CLEAVAGE; S PHASE CELL CYCLE CHECKPOINT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADULT; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FLAVONOIDS; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; S PHASE CELL CYCLE CHECKPOINTS; SIGNAL TRANSDUCTION; U937 CELLS; YOUNG ADULT;

EID: 84878015872     PISSN: 09255710     EISSN: 18653774     Source Type: Journal    
DOI: 10.1007/s12185-013-1317-9     Document Type: Article

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