Brain-derived neurotrophic factor stimulates the neural differentiation of human umbilical cord blood-derived mesenchymal stem cells and survival of differentiated cells through MAPK/ERK and PI3K/Akt-dependent signaling pathways

Journal of Neuroscience Research

Volumn 86, Issue 10, 2008, Pages 2168-2178

  Jung, Yeon Lim ^a   Sang, In Park ^a   Ji, Hyeon Oh ^a   Seong, Muk Kim ^a   Chang, Hyun Jeong ^a   Jin, Ae Jun ^a   Lee, Kwan Sung ^a   Oh, Wonil ^b   Lee, Jae Kwon ^c   Jeun, Sin Soo ^a  

^a The Catholic University of Korea   (South Korea)

^b MEDIPOST Co Ltd   (South Korea)

^c Chungbuk National University   (South Korea)

Author keywords

Apoptosis; Bcl2; BDNF; Brain derived neurotrophic factor; ERKs; Neural differentiation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P35; RAF PROTEIN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; MESENCHYMAL STEM CELL; NERVE CELL DIFFERENTIATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UMBILICAL CORD BLOOD; UPREGULATION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FETAL BLOOD; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MESENCHYMAL STEM CELLS; NERVE TISSUE PROTEINS; NEURONS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 48249106653     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21669     Document Type: Article

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