-
1
-
-
0041856595
-
Epidemiology of neurodegeneration
-
PMID: 12574495
-
Mayeux R. Epidemiology of neurodegeneration. Ann Rev Neurosci. 2003; 26:81-104. PMID: 12574495
-
(2003)
Ann Rev Neurosci
, vol.26
, pp. 81-104
-
-
Mayeux, R.1
-
2
-
-
0030882856
-
Alpha-synuclein in lewy bodies
-
PMID: 9278044
-
Spillantini MG, Schmidt ML, Lee V.M., Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997; 388:839-840. PMID: 9278044
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
3
-
-
4644290985
-
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
-
PMID: 15451224
-
Chartier-Harlin M.C., Kachergus J, Roumier C, Mouroux V, Douay X, Lincoln S, et al. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet. 2004; 364:1167-1169. PMID: 15451224
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
-
4
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease
-
PMID: 9809558
-
Conway KA, Harper JD, Lansbury PT Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease. Nat Med. 1998; 4:1318-1320. PMID: 9809558
-
(1998)
Nat Med.
, vol.4
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
5
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and lewy body dementia
-
PMID: 14755719
-
Zarranz JJ, Alegre J, Gomez-Esteban JC, Lezcano E., Ros R, Ampuero I, et al The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann Neurol. 2004; 55:164-173. PMID: 14755719
-
(2004)
Ann Neurol
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
-
6
-
-
84901361843
-
Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease
-
PMID: 24810576
-
Tenreiro S, Reimao-Pinto MM, Antas P, Rino J, Wawrzycka D, Macedo D, et al. Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease. PLoS Genet. 2014; 10:e1004302. doi: 10.1371/journal.pgen.1004302 PMID: 24810576
-
(2014)
PLoS Genet
, vol.10
-
-
Tenreiro, S.1
Reimao-Pinto, M.M.2
Antas, P.3
Rino, J.4
Wawrzycka, D.5
Macedo, D.6
-
7
-
-
84907190544
-
Phosphatidylethanolamine deficiency disrupts alpha-synuclein homeostasis in yeast and worm models of Parkinson disease
-
PMID: 25201965
-
Wang S, Zhang S, Liou L.C., Ren Q., Zhang Z, Caldwell GA, et al Phosphatidylethanolamine deficiency disrupts alpha-synuclein homeostasis in yeast and worm models of Parkinson disease. Proc Natl Acad Sci USA. 2014; 111: E3976-3985. doi: 10.1073/pnas.1411694111 PMID: 25201965
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E3976-E3985
-
-
Wang, S.1
Zhang, S.2
Liou, L.C.3
Ren, Q.4
Zhang, Z.5
Caldwell, G.A.6
-
8
-
-
0034704752
-
A drosophila model of Parkinson's disease
-
PMID: 10746727
-
Feany MB, Bender WW A Drosophila model of Parkinson's disease. Nature. 2000; 404:394-398. PMID: 10746727
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
9
-
-
84923491254
-
FK506 reduces neuroinflammation and dopaminergic neurodegeneration in an alpha-synuclein-based rat model for Parkinson's disease
-
PMID: 25660193
-
Van der Perren A, Macchi F, Toelen J, Carlon MS, Maris M, de Loor H, et al. FK506 reduces neuroinflammation and dopaminergic neurodegeneration in an alpha-synuclein-based rat model for Parkinson's disease. Neurobiol Aging. 2015; 36:1559-1568. doi: 10.1016/j.neurobiolaging.2015.01.014 PMID: 25660193
-
(2015)
Neurobiol Aging
, vol.36
, pp. 1559-1568
-
-
Van Der Perren, A.1
Macchi, F.2
Toelen, J.3
Carlon, M.S.4
Maris, M.5
De Loor, H.6
-
10
-
-
84921456454
-
A53T human alpha-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration
-
PMID: 25609609
-
Chen L, Xie Z, Turkson S., Zhuang X. A53T human alpha-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration. J Neurosci. 2015; 35:890-905. doi: 10.1523/JNEUROSCI.0089-14.2015 PMID: 25609609
-
(2015)
J Neurosci
, vol.35
, pp. 890-905
-
-
Chen, L.1
Xie, Z.2
Turkson, S.3
Zhuang, X.4
-
11
-
-
84858621036
-
Long-term polarization of microglia upon alpha-synuclein overexpression in nonhuman primates
-
PMID: 22342967
-
Barkholt P, Sanchez-Guajardo V, Kirik D, Romero-Ramos M. Long-term polarization of microglia upon alpha-synuclein overexpression in nonhuman primates. Neuroscience. 2012; 208:85-96. doi: 10. 1016/j.neuroscience.2012.02.004 PMID: 22342967
-
(2012)
Neuroscience
, vol.208
, pp. 85-96
-
-
Barkholt, P.1
Sanchez-Guajardo, V.2
Kirik, D.3
Romero-Ramos, M.4
-
12
-
-
84928143350
-
Drosophila models of Alzheimer's disease: Advances, limits, and perspectives
-
PMID: 25697708
-
Bouleau S, Tricoire H. Drosophila models of Alzheimer's disease: advances, limits, and perspectives. J Alzheimers Dis. 2015; 45:1015-1038. doi: 10.3233/JAD-142802 PMID: 25697708
-
(2015)
J Alzheimers Dis
, vol.45
, pp. 1015-1038
-
-
Bouleau, S.1
Tricoire, H.2
-
13
-
-
84898811573
-
Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of huntington's disease
-
PMID: 24381308
-
Maheshwari M, Bhutani S, Das A., Mukherjee R, Sharma A, Kino Y, et al. Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntington's disease. Hum Mol Genet. 2014; 23:2737-2751. doi: 10.1093/hmg/ddt667 PMID: 24381308
-
(2014)
Hum Mol Genet
, vol.23
, pp. 2737-2751
-
-
Maheshwari, M.1
Bhutani, S.2
Das, A.3
Mukherjee, R.4
Sharma, A.5
Kino, Y.6
-
14
-
-
17844406856
-
Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a drosophila model of Parkinson disease
-
PMID: 15834418
-
Chen L, Feany MB Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat Neurosci. 2005; 8:657-663. PMID: 15834418
-
(2005)
Nat Neurosci
, vol.8
, pp. 657-663
-
-
Chen, L.1
Feany, M.B.2
-
15
-
-
33947505619
-
Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo
-
PMID: 17376994
-
Periquet M, Fulga T, Myllykangas L, Schlossmacher MG, Feany MB. Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo. J Neurosci. 2007; 27:3338-3346. PMID: 17376994
-
(2007)
J Neurosci
, vol.27
, pp. 3338-3346
-
-
Periquet, M.1
Fulga, T.2
Myllykangas, L.3
Schlossmacher, M.G.4
Feany, M.B.5
-
16
-
-
81355142141
-
Non-coding RNAs in human disease
-
PMID: 22094949
-
Esteller M. Non-coding RNAs in human disease. Nat Rev Genet. 2011; 12:861-874. doi: 10.1038/nrg3074 PMID: 22094949
-
(2011)
Nat Rev Genet
, vol.12
, pp. 861-874
-
-
Esteller, M.1
-
17
-
-
84897517156
-
Gene and micro-RNA transcriptome analysis of Parkinson's related LRRK2 mouse models
-
PMID: 24427314
-
Dorval V, Mandemakers W, Jolivette F., Coudert L, Mazroui R, De Strooper B, et al. Gene and Micro-RNA transcriptome analysis of Parkinson's related LRRK2 mouse models. PloSOne. 2014; 9:e85510. doi: 10.1371/journal.pone.0085510 PMID: 24427314
-
(2014)
PloSOne
, vol.9
-
-
Dorval, V.1
Mandemakers, W.2
Jolivette, F.3
Coudert, L.4
Mazroui, R.5
De Strooper, B.6
-
18
-
-
84891391234
-
Profile of microRNAs in the plasma of Parkinson's disease patients and healthy controls
-
PMID: 23543376
-
Cardo LF, Coto E, de Mena L, Ribacoba R, Moris G., Menendez M, et al. Profile of microRNAs in the plasma of Parkinson's disease patients and healthy controls. J Neurol. 2013; 260:1420-1422. doi: 10. 1007/s00415-013-6900-8 PMID: 23543376
-
(2013)
J Neurol
, vol.260
, pp. 1420-1422
-
-
Cardo, L.F.1
Coto, E.2
De Mena, L.3
Ribacoba, R.4
Moris, G.5
Menendez, M.6
-
19
-
-
79960135400
-
MicroRNAprofiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
-
PMID: 21558425
-
Minones-Moyano E., Porta S, Escaramis G, Rabionet R, Iraola S, Kagerbauer B, et al. MicroRNAprofiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function. Hum Mol Genet. 2011; 20:3067-3068. doi: 10.1093/hmg/ddr210 PMID: 21558425
-
(2011)
Hum Mol Genet
, vol.20
, pp. 3067-3068
-
-
Minones-Moyano, E.1
Porta, S.2
Escaramis, G.3
Rabionet, R.4
Iraola, S.5
Kagerbauer, B.6
-
20
-
-
79952898846
-
Identification of blood microRNAs associated to Parkinsonis disease
-
PMID: 21295623
-
Margis R, Margis R, Rieder CR. Identification of blood microRNAs associated to Parkinsonis disease. J Biotechnol. 2011; 152:96-101. doi: 10.1016/j.jbiotec.2011.01.023 PMID: 21295623
-
(2011)
J Biotechnol
, vol.152
, pp. 96-101
-
-
Margis, R.1
Margis, R.2
Rieder, C.R.3
-
21
-
-
84864464973
-
DIANA miRPath v.2.0: Investigating the combinatorial effect of microRNAs in pathways
-
Web Server issue PMID: 22649059
-
Vlachos IS, Kostoulas N, Vergoulis T., Georgakilas G, Reczko M, Maragkakis M., et al. DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Res. 2012; 40 (Web Server issue):W498-504. doi: 10.1093/nar/gks494 PMID: 22649059
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. W498-W504
-
-
Vlachos, I.S.1
Kostoulas, N.2
Vergoulis, T.3
Georgakilas, G.4
Reczko, M.5
Maragkakis, M.6
-
22
-
-
84899072060
-
Detecting genetic interactions in pathway-based genome-wide association studies
-
Huang A, Martin ER, Vance J.M., Cai X. Detecting genetic interactions in pathway-based genome-wide association studies. Genetic Epidemiol. 2014; 38:300-309.
-
(2014)
Genetic Epidemiol
, vol.38
, pp. 300-309
-
-
Huang, A.1
Martin, E.R.2
Vance, J.M.3
Cai, X.4
-
23
-
-
84926139786
-
MIR137 variants identified in psychiatric patients affect synaptogenesis and neuronal transmission gene sets
-
PMID: 24888363
-
Strazisar M, Cammaerts S, van der Ven K, Forero DA, Lenaerts AS, Nordin A, et al. MIR137 variants identified in psychiatric patients affect synaptogenesis and neuronal transmission gene sets. Mol Psychiatry. 2015; 20:472-481. doi: 10.1038/mp.2014.53 PMID: 24888363
-
(2015)
Mol Psychiatry
, vol.20
, pp. 472-481
-
-
Strazisar, M.1
Cammaerts, S.2
Van Der Ven, K.3
Forero, D.A.4
Lenaerts, A.S.5
Nordin, A.6
-
24
-
-
84888386831
-
MiR-137, a new target for post-stroke depression?
-
PMID: 25206554
-
Zhao L, Li H, Guo R., Ma T, Hou R, Ma X, et al. miR-137, a new target for post-stroke depression? Neural Regen Res. 2013; 8:2441-2448. doi: 10.3969/j.issn.1673-5374.2013.26.005 PMID: 25206554
-
(2013)
Neural Regen Res.
, vol.8
, pp. 2441-2448
-
-
Zhao, L.1
Li, H.2
Guo, R.3
Ma, T.4
Hou, R.5
Ma, X.6
-
25
-
-
84888880539
-
Endonuclease G mediates alpha-synuclein cytotoxicity during Parkinson's disease
-
PMID: 24129513
-
Buttner S, Habernig L, Broeskamp F., Ruli D, Vogtle FN, Vlachos M, et al Endonuclease G mediates alpha-synuclein cytotoxicity during Parkinson's disease. EMBO J. 2013; 32:3041-3054. doi: 10.1038/emboj.2013.228 PMID: 24129513
-
(2013)
EMBO J.
, vol.32
, pp. 3041-3054
-
-
Buttner, S.1
Habernig, L.2
Broeskamp, F.3
Ruli, D.4
Vogtle, F.N.5
Vlachos, M.6
-
26
-
-
34547599329
-
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
-
PMID: 17588900
-
Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, et al. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science 2007; 317:516-519. PMID: 17588900
-
(2007)
Science
, vol.317
, pp. 516-519
-
-
Outeiro, T.F.1
Kontopoulos, E.2
Altmann, S.M.3
Kufareva, I.4
Strathearn, K.E.5
Amore, A.M.6
-
27
-
-
84906503242
-
VPS35dysfunction impairs lysosomal degradation of alpha-synuclein and exacerbates neurotoxicity in a drosophila model of Parkinson's disease
-
PMID: 25107340
-
Miura E, Hasegawa T, Konno M, Suzuki M, Sugeno N, Fujikake N, et al. VPS35dysfunction impairs lysosomal degradation of alpha-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease. Neurobiol Dis. 2014; 71:1-13. doi: 10.1016/j.nbd.2014.07.014 PMID: 25107340
-
(2014)
Neurobiol Dis
, vol.71
, pp. 1-13
-
-
Miura, E.1
Hasegawa, T.2
Konno, M.3
Suzuki, M.4
Sugeno, N.5
Fujikake, N.6
-
28
-
-
84904559577
-
Alpha-synuclein interacts with the switch region of rab8a in a ser129 phosphorylation-dependent manner
-
Yin G, Lopes da Fonseca T, Eisbach SE, Anduaga AM, Breda C, Orcellet ML, et al. alpha-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner. Neurobiol Disease 2014; 70:149-161.
-
(2014)
Neurobiol Disease
, vol.70
, pp. 149-161
-
-
Yin, G.1
Lopes da Fonseca, T.2
Eisbach, S.E.3
Anduaga, A.M.4
Breda, C.5
Orcellet, M.L.6
-
29
-
-
84859169870
-
The mitochondrial chaperone protein TRAP1 mitigates alpha-synuclein toxicity
-
PMID: 22319455
-
Butler EK, Voigt A, Lutz A.K., Toegel JP, Gerhardt E, Karsten P, et al The mitochondrial chaperone protein TRAP1 mitigates alpha-Synuclein toxicity. PLoS Genet. 2012; 8:e1002488. doi: 10.1371/journal. pgen.1002488 PMID: 22319455
-
(2012)
PLoS Genet
, vol.8
-
-
Butler, E.K.1
Voigt, A.2
Lutz, A.K.3
Toegel, J.P.4
Gerhardt, E.5
Karsten, P.6
-
30
-
-
80052277569
-
Genetic activation of nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a drosophila model of Parkinson's disease
-
PMID: 21719443
-
Barone MC, Sykiotis GP, Bohmann D. Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease. Dis Model Mech. 2011; 4:701-707. doi: 10.1242/dmm.007575 PMID: 21719443
-
(2011)
Dis Model Mech
, vol.4
, pp. 701-707
-
-
Barone, M.C.1
Sykiotis, G.P.2
Bohmann, D.3
-
31
-
-
77957189194
-
Alpha-synuclein impairs macroautophagy: Implications for Parkinson's disease
-
PMID: 20855506
-
Winslow AR, Chen CW, Corrochano S, Acevedo-Arozena A, Gordon DE, Peden AA, et al. alpha-Synuclein impairs macroautophagy: implications for Parkinson's disease. J Cell Biol. 2010; 190:1023-1037. doi: 10.1083/jcb.201003122 PMID: 20855506
-
(2010)
J Cell Biol
, vol.190
, pp. 1023-1037
-
-
Winslow, A.R.1
Chen, C.W.2
Corrochano, S.3
Acevedo-Arozena, A.4
Gordon, D.E.5
Peden, A.A.6
-
32
-
-
77954208049
-
Drosophila histone deacetylase 6 protects dopaminergic neurons against {alpha}-synuclein toxicity by promoting inclusion formation
-
PMID: 20444973
-
Du G, Liu X, Chen X., Song M, Yan Y, Jiao R., et al. Drosophila histone deacetylase 6 protects dopaminergic neurons against {alpha}-synuclein toxicity by promoting inclusion formation. Mol Biol Cell. 2010; 21:2128-2137. doi: 10.1091/mbc.E10-03-0200 PMID: 20444973
-
(2010)
Mol Biol Cell
, vol.21
, pp. 2128-2137
-
-
Du, G.1
Liu, X.2
Chen, X.3
Song, M.4
Yan, Y.5
Jiao, R.6
-
33
-
-
57149110259
-
Pink1 suppresses alpha-synuclein-induced phenotypes in a drosophila model of Parkinson's disease
-
PMID: 19088817
-
Todd AM, Staveley BE Pink1 suppresses alpha-synuclein-induced phenotypes in a Drosophila model of Parkinson's disease. Genome. 2008; 51:1040-1046. doi: 10.1139/G08-085 PMID: 19088817
-
(2008)
Genome
, vol.51
, pp. 1040-1046
-
-
Todd, A.M.1
Staveley, B.E.2
-
34
-
-
40849130108
-
Superoxide dismutase overexpression protects dopaminergic neurons in a drosophila model of Parkinson's disease
-
PMID: 18243716
-
Botella JA, Bayersdorfer F, Schneuwly S. Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease. Neurobiol Dis. 2008; 30:65-73. doi: 10. 1016/j.nbd.2007.11.013 PMID: 18243716
-
(2008)
Neurobiol Dis
, vol.30
, pp. 65-73
-
-
Botella, J.A.1
Bayersdorfer, F.2
Schneuwly, S.3
-
35
-
-
36349025347
-
Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms
-
PMID: 18032652
-
Wassef R, Haenold R, Hansel A., Brot N, Heinemann SH, Hoshi T. Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms. J Neurosci. 2007; 27:12808-12816. PMID: 18032652
-
(2007)
J Neurosci
, vol.27
, pp. 12808-12816
-
-
Wassef, R.1
Haenold, R.2
Hansel, A.3
Brot, N.4
Heinemann, S.H.5
Hoshi, T.6
-
36
-
-
2642516493
-
Parkin counteracts symptoms in a drosophila model of Parkinson's disease
-
PMID: 15090075
-
Haywood AF, Staveley BE Parkin counteracts symptoms in a Drosophila model of Parkinson's disease. BMC Neurosci. 2004; 5:14. PMID: 15090075
-
(2004)
BMC Neurosci
, vol.5
, pp. 14
-
-
Haywood, A.F.1
Staveley, B.E.2
-
37
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a drosophila model for Parkinson's disease
-
PMID: 11823645
-
Auluck PK, Chan HY, Trojanowski J.Q., Lee VM, Bonini NM. Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science. 2002; 295:865-868. PMID: 11823645
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
38
-
-
0036137083
-
Effects of pharmacological agents upon a transgenic model of Parkinson's disease in drosophila melanogaster
-
PMID: 11752102
-
Pendleton RG, Parvez F, Sayed M., Hillman R. Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster. J Pharmacol ExpTher. 2002; 300:91-96. PMID: 11752102
-
(2002)
J Pharmacol ExpTher
, vol.300
, pp. 91-96
-
-
Pendleton, R.G.1
Parvez, F.2
Sayed, M.3
Hillman, R.4
-
39
-
-
84920719693
-
Spermidine protects against alpha-synuclein neurotoxicity
-
PMID: 25483063
-
Buttner S, Broeskamp F, Sommer C, Markaki M, Habernig L, Alavian-Ghavanini A, et al. Spermidine protects against alpha-synuclein neurotoxicity. Cell cycle. 2014; 13:3903-3908. doi: 10.4161/15384101.2014.973309 PMID: 25483063
-
(2014)
Cell Cycle
, vol.13
, pp. 3903-3908
-
-
Buttner, S.1
Broeskamp, F.2
Sommer, C.3
Markaki, M.4
Habernig, L.5
Alavian-Ghavanini, A.6
-
40
-
-
84860453973
-
The role of the GABA(B) receptor and calcium channels in a drosophila model of Parkinson's disease
-
PMID: 22480689
-
Hillman R, Sinani J, Pendleton R. The role of the GABA(B) receptor and calcium channels in a Drosophila model of Parkinson's Disease. Neurosci Lett. 2012; 516:167-170. doi: 10.1016/j.neulet.2012. 03.034 PMID: 22480689
-
(2012)
Neurosci Lett.
, vol.516
, pp. 167-170
-
-
Hillman, R.1
Sinani, J.2
Pendleton, R.3
-
41
-
-
84869774755
-
Effect of L-ascorbic acid on the climbing ability and protein levels in the brain of drosophila model of Parkinson's disease
-
PMID: 22776006
-
Khan S, Jyoti S, Naz F., Shakya B, Rahul, Afzal M, et al. Effect of L-ascorbic Acid on the climbing ability and protein levels in the brain of Drosophila model of Parkinson's disease. Int J Neurosci. 2012; 122:704-709. doi: 10.3109/00207454.2012.709893 PMID: 22776006
-
(2012)
Int J Neurosci
, vol.122
, pp. 704-709
-
-
Khan, S.1
Jyoti, S.2
Naz, F.3
Shakya, B.4
Rahul5
Afzal, M.6
-
42
-
-
84857419171
-
The dietary supplementation of nordihydroguaiaretic acid (NDGA) delayed the loss of climbing ability in drosophila model of Parkinson's disease
-
PMID: 22432798
-
Siddique YH, Ara G, Jyoti S., Afzal M. The dietary supplementation of nordihydroguaiaretic acid (NDGA) delayed the loss of climbing ability in Drosophila model of Parkinson's disease. J Diet Suppl. 2012; 9:1-8. doi: 10.3109/19390211.2011.630716 PMID: 22432798
-
(2012)
J Diet Suppl
, vol.9
, pp. 1-8
-
-
Siddique, Y.H.1
Ara, G.2
Jyoti, S.3
Afzal, M.4
-
43
-
-
84863442695
-
Differential inhibition of alpha-synuclein oligomeric and fibrillar assembly in Parkinson's disease model by cinnamon extract
-
PMID: 22575665
-
Shaltiel-Karyo R., Davidi D, Frenkel-Pinter M, Ovadia M., Segal D, Gazit E. Differential inhibition of alpha-synuclein oligomeric and fibrillar assembly in Parkinson's disease model by cinnamon extract. Biochim Biophys Acta. 2012; 1820:1628-1635. doi: 10.1016/j.bbagen.2012.04.021 PMID: 22575665
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 1628-1635
-
-
Shaltiel-Karyo, R.1
Davidi, D.2
Frenkel-Pinter, M.3
Ovadia, M.4
Segal, D.5
Gazit, E.6
-
44
-
-
13244267202
-
Mechanisms of suppression of {alpha}-synuclein neurotoxicity by geldanamycin in drosophila
-
PMID: 15556931
-
Auluck PK, Meulener MC, Bonini NM Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila. J Biol Chem. 2005; 280:2873-2878. PMID: 15556931
-
(2005)
J Biol Chem
, vol.280
, pp. 2873-2878
-
-
Auluck, P.K.1
Meulener, M.C.2
Bonini, N.M.3
-
45
-
-
84863012020
-
Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy
-
PMID: 22113202
-
Lu JH, Tan JQ, Durairajan S.S., Liu LF, Zhang ZH, Ma L, et al Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy. Autophagy. 2012; 8:98-108. doi: 10.4161/auto.8.1.18313 PMID: 22113202
-
(2012)
Autophagy
, vol.8
, pp. 98-108
-
-
Lu, J.H.1
Tan, J.Q.2
Durairajan, S.S.3
Liu, L.F.4
Zhang, Z.H.5
Ma, L.6
-
46
-
-
84900026819
-
Effect of curcumin on lifespan, activity pattern, oxidative stress, and apoptosis in the brains of transgenic drosophila model of Parkinson's disease
-
PMID: 24860828
-
Siddique YH, Naz F, Jyoti S. Effect of curcumin on lifespan, activity pattern, oxidative stress, and apoptosis in the brains of transgenic Drosophila model of Parkinson's disease. Biomed Res Int. 2014; 2014:606928. doi: 10.1155/2014/606928 PMID: 24860828
-
(2014)
Biomed Res Int
, vol.2014
-
-
Siddique, Y.H.1
Naz, F.2
Jyoti, S.3
-
47
-
-
84896990853
-
Effect of epicatechin gallate dietary supplementation on transgenic drosophila model of Parkinson's disease
-
PMID: 24670116
-
Siddique YH, Jyoti S, Naz F. Effect of epicatechin gallate dietary supplementation on transgenic Drosophila model of Parkinson's disease. J Diet Suppl. 2014; 11:121-130. doi: 10.3109/19390211.2013. 859207 PMID: 24670116
-
(2014)
J Diet Suppl
, vol.11
, pp. 121-130
-
-
Siddique, Y.H.1
Jyoti, S.2
Naz, F.3
-
48
-
-
84879052027
-
Abloodbrain Barrier (BBB) disrupter is also a potent alpha-synuclein (alpha-syn) aggregation inhibitor: A novel dual mechanism of mannitol for the treatment of Parkinson disease (PD)
-
PMID: 23637226
-
Shaltiel-Karyo R., Frenkel-Pinter M, Rockenstein E., Patrick C, Levy-Sakin M, Schiller A, et al. Abloodbrain barrier (BBB) disrupter is also a potent alpha-synuclein (alpha-syn) aggregation inhibitor: a novel dual mechanism of mannitol for the treatment of Parkinson disease (PD). J Biol Chem. 2013; 288:17579-17588. doi: 10.1074/jbc.M112.434787 PMID: 23637226
-
(2013)
J Biol Chem
, vol.288
, pp. 17579-17588
-
-
Shaltiel-Karyo, R.1
Frenkel-Pinter, M.2
Rockenstein, E.3
Patrick, C.4
Levy-Sakin, M.5
Schiller, A.6
-
49
-
-
84879420897
-
Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced drosophila model of Parkinson's disease
-
PMID: 23623990
-
St Laurent R., O'Brien LM, Ahmad ST Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease. Neuroscience. 2013; 246:382-390. doi: 10.1016/j.neuroscience.2013.04.037 PMID: 23623990
-
(2013)
Neuroscience
, vol.246
, pp. 382-390
-
-
St. Laurent, R.1
O'Brien, L.M.2
Ahmad, S.T.3
-
50
-
-
84922568853
-
Roleof ocimum sanctum leaf extract on dietary supplementation in the transgenic drosophila model of Parkinson's disease
-
PMID: 25443371
-
Siddique YH, Faisal M, Naz F., Jyoti S, Rahul. Roleof Ocimum sanctum leaf extract on dietary supplementation in the transgenic Drosophila model of Parkinson's disease. Chin J Nat Med. 2014; 12:777-781. doi: 10.1016/S1875-5364(14)60118-7 PMID: 25443371
-
(2014)
Chin J Nat Med.
, vol.12
, pp. 777-781
-
-
Siddique, Y.H.1
Faisal, M.2
Naz, F.3
Jyoti, S.4
Rahul5
-
51
-
-
84873244576
-
GC-MS analysis of eucalyptus citriodora leaf extract and its role on the dietary supplementation in transgenic drosophila model of Parkinson's disease
-
PMID: 23318758
-
Siddique YH, Mujtaba SF, Jyoti S, Naz F. GC-MS analysis of Eucalyptus citriodora leaf extract and its role on the dietary supplementation in transgenic Drosophila model of Parkinson's disease. Food Chem Toxicol. 2013; 55:29-35. doi: 10.1016/j.fct.2012.12.028 PMID: 23318758
-
(2013)
Food Chem Toxicol
, vol.55
, pp. 29-35
-
-
Siddique, Y.H.1
Mujtaba, S.F.2
Jyoti, S.3
Naz, F.4
-
52
-
-
70450285045
-
Grape extract protects mitochondria from oxidative damage and improves locomotor dysfunction and extends lifespan in a drosophila Parkinson's disease model
-
PMID: 19929256
-
Long J, Gao H, Sun L., Liu J, Zhao-Wilson X. Grape extract protects mitochondria from oxidative damage and improves locomotor dysfunction and extends lifespan in a Drosophila Parkinson's disease model. Rejuvenation Res. 2009, 12:321-331. doi: 10.1089/rej.2009.0877 PMID: 19929256
-
(2009)
Rejuvenation Res.
, vol.12
, pp. 321-331
-
-
Long, J.1
Gao, H.2
Sun, L.3
Liu, J.4
Zhao-Wilson, X.5
-
53
-
-
84921521998
-
Inhibition of miR-34b and miR-34c enhances alpha-synuclein expression in Parkinson's disease
-
PMID: 25541488
-
Kabaria S, Choi DC, Chaudhuri A.D., Mouradian MM, Junn E. Inhibition of miR-34b and miR-34c enhances alpha-synuclein expression in Parkinson's disease. FEBS Lett. 2015; 589:319-325. doi: 10. 1016/j.febslet.2014.12.014 PMID: 25541488
-
(2015)
FEBS Lett.
, vol.589
, pp. 319-325
-
-
Kabaria, S.1
Choi, D.C.2
Chaudhuri, A.D.3
Mouradian, M.M.4
Junn, E.5
-
54
-
-
77951249562
-
Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153
-
PMID: 20106983
-
Doxakis E. Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153. J Biol Chem. 2010; 285:12726-12734. doi: 10.1074/jbc.M109.086827 PMID: 20106983
-
(2010)
J Biol Chem
, vol.285
, pp. 12726-12734
-
-
Doxakis, E.1
-
55
-
-
34548537573
-
A MicroRNA feedback circuit in midbrain dopamine neurons
-
PMID: 17761882
-
Kim J, Inoue K, Ishii J., Vanti WB, Voronov SV, Murchison E, et al A MicroRNA feedback circuit in midbrain dopamine neurons. Science. 2007; 317:1220-1224. PMID: 17761882
-
(2007)
Science
, vol.317
, pp. 1220-1224
-
-
Kim, J.1
Inoue, K.2
Ishii, J.3
Vanti, W.B.4
Voronov, S.V.5
Murchison, E.6
-
56
-
-
84877351078
-
TFEB-mediated autophagy rescues midbrain dopamine neurons from alpha-synuclein toxicity
-
PMID: 23610405
-
Decressac M, Mattsson B, Weikop P., Lundblad M, Jakobsson J, Bjorklund A. TFEB-mediated autophagy rescues midbrain dopamine neurons from alpha-synuclein toxicity. Proc Natl Acad Sci USA. 2013; 110: E1817-1826. doi: 10.1073/pnas.1305623110 PMID: 23610405
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E1817-E1826
-
-
Decressac, M.1
Mattsson, B.2
Weikop, P.3
Lundblad, M.4
Jakobsson, J.5
Bjorklund, A.6
-
57
-
-
51349103571
-
Sequence relationships among C. Elegans, D. Melanogaster and human microRNAs highlight the extensive conservation of microRNAs in biology
-
PMID: 18665242
-
Ibanez-Ventoso C., Vora M, Driscoll M. Sequence relationships among C. elegans, D. melanogaster and human microRNAs highlight the extensive conservation of microRNAs in biology. PloS One. 2008; 3:e2818. doi: 10.1371/journal.pone.0002818 PMID: 18665242
-
(2008)
PloS One
, vol.3
-
-
Ibanez-Ventoso, C.1
Vora, M.2
Driscoll, M.3
-
58
-
-
84872934580
-
Association of the miR-146a, miR-149, miR-196a2, andmiR-499 polymorphisms with ischemic stroke and silent brain infarction risk
-
PMID: 23202363
-
Jeon YJ, Kim OJ, Kim S.Y., Oh SH, Oh D, Kim OJ, et al Association of the miR-146a, miR-149, miR-196a2, andmiR-499 polymorphisms with ischemic stroke and silent brain infarction risk. Arterioscler thromb Vasc Biol. 2013; 33:420-430. doi: 10.1161/ATVBAHA.112.300251 PMID: 23202363
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 420-430
-
-
Jeon, Y.J.1
Kim, O.J.2
Kim, S.Y.3
Oh, S.H.4
Oh, D.5
Kim, O.J.6
-
59
-
-
84911454956
-
MicroRNA expression analysis of adult-onset drosophila Alzheimer's disease model
-
PMID: 25274109
-
Kong Y, Wu J, Yuan L. MicroRNA expression analysis of adult-onset Drosophila Alzheimer's disease model. Curr Alzheimer Res. 2014; 11:882-891. PMID: 25274109
-
(2014)
Curr Alzheimer Res.
, vol.11
, pp. 882-891
-
-
Kong, Y.1
Wu, J.2
Yuan, L.3
-
60
-
-
84862867271
-
Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth
-
PMID: 22605481
-
Xin H, Li Y, Buller B., Katakowski M, Zhang Y, Wang X., et al. Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth. Stem Cells. 2012; 30:1556-1564. doi: 10.1002/stem.1129 PMID: 22605481
-
(2012)
Stem Cells
, vol.30
, pp. 1556-1564
-
-
Xin, H.1
Li, Y.2
Buller, B.3
Katakowski, M.4
Zhang, Y.5
Wang, X.6
-
61
-
-
77958121077
-
Morphine regulates dopaminergic neuron differentiation via miR-133b
-
PMID: 20716624
-
Sanchez-Simon F.M., Zhang XX, Loh H.H., Law PY, Rodriguez RE. Morphine regulates dopaminergic neuron differentiation via miR-133b. Mol Pharmacol. 2010; 78:935-942. doi: 10.1124/mol.110.066837 PMID: 20716624
-
(2010)
Mol Pharmacol
, vol.78
, pp. 935-942
-
-
Sanchez-Simon, F.M.1
Zhang, X.X.2
Loh, H.H.3
Law, P.Y.4
Rodriguez, R.E.5
-
62
-
-
79955534061
-
MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish
-
PMID: 21447094
-
Yu YM, Gibbs KM, Davila J, Campbell N., Sung S, Todorova TI, et al. MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. Eur J Neurosci. 2011; 33:1587-1597. doi: 10.1111/j.1460-9568.2011.07643.x PMID: 21447094
-
(2011)
Eur J Neurosci
, vol.33
, pp. 1587-1597
-
-
Yu, Y.M.1
Gibbs, K.M.2
Davila, J.3
Campbell, N.4
Sung, S.5
Todorova, T.I.6
-
63
-
-
82555196537
-
MiR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells
-
Sun G, Ye P, Murai K., Lang MF, Li S, Zhang H, et al miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. Nature Commun. 2011; 2:529.
-
(2011)
Nature Commun
, vol.2
, pp. 529
-
-
Sun, G.1
Ye, P.2
Murai, K.3
Lang, M.F.4
Li, S.5
Zhang, H.6
-
64
-
-
77956114374
-
MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1
-
PMID: 20506192
-
Smrt RD, Szulwach KE, Pfeiffer R.L., Li X., Guo W, Pathania M, et al. MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1. Stem Cells. 2010; 28:1060-1070. doi: 10. 1002/stem.431 PMID: 20506192
-
(2010)
Stem Cells
, vol.28
, pp. 1060-1070
-
-
Smrt, R.D.1
Szulwach, K.E.2
Pfeiffer, R.L.3
Li, X.4
Guo, W.5
Pathania, M.6
-
65
-
-
84923763986
-
A neuroprotective role for microRNAmiR-1000 mediated by limiting glutamate excitotoxicity
-
PMID: 25643297
-
Verma P, Augustine GJ, Ammar MR, Tashiro A, Cohen SM. A neuroprotective role for microRNAmiR-1000 mediated by limiting glutamate excitotoxicity. Nature Neurosci. 2015; 18:379-385. doi: 10.1038/nn.3935 PMID: 25643297
-
(2015)
Nature Neurosci
, vol.18
, pp. 379-385
-
-
Verma, P.1
Augustine, G.J.2
Ammar, M.R.3
Tashiro, A.4
Cohen, S.M.5
-
66
-
-
84855996171
-
Chromosome 1p21.3 microdeletions comprising DPYDand MIR137 are associated with intellectual disability
-
PMID: 22003227
-
Willemsen MH, Valles A, Kirkels L.A., Mastebroek M, Olde Loohuis N, Kos A, et al. Chromosome 1p21.3 microdeletions comprising DPYDand MIR137 are associated with intellectual disability. J Med Genet. 2011; 48:810-818. doi: 10.1136/jmedgenet-2011-100294 PMID: 22003227
-
(2011)
J Med Genet
, vol.48
, pp. 810-818
-
-
Willemsen, M.H.1
Valles, A.2
Kirkels, L.A.3
Mastebroek, M.4
Olde Loohuis, N.5
Kos, A.6
-
67
-
-
84888147358
-
Potential impact of miR-137 and its targets in schizophrenia
-
PMID: 23637704
-
Wright C, Turner JA, Calhoun V.D., Perrone-Bizzozero N. Potential Impact of miR-137 and Its Targets in Schizophrenia. Front Genet. 2013; 4:58. doi: 10.3389/fgene.2013.00058 PMID: 23637704
-
(2013)
Front Genet
, vol.4
, pp. 58
-
-
Wright, C.1
Turner, J.A.2
Calhoun, V.D.3
Perrone-Bizzozero, N.4
-
68
-
-
84894254200
-
MiR-137: A new player in schizophrenia
-
PMID: 24566148
-
Yin J, Lin J, Luo X, Chen Y, Li Z, Ma G, Li K. miR-137: a new player in schizophrenia. Int J Mol Sci. 2014; 15:3262-3271. doi: 10.3390/ijms15023262 PMID: 24566148
-
(2014)
Int J Mol Sci.
, vol.15
, pp. 3262-3271
-
-
Yin, J.1
Lin, J.2
Luo, X.3
Chen, Y.4
Li, Z.5
Ma, G.6
Li, K.7
-
69
-
-
84892453822
-
Genetic comorbidities in Parkinson's disease
-
PMID: 24057672
-
Nalls MA, Saad M, Noyce A.J., Keller MF, Schrag A, Bestwick JP, et al Genetic comorbidities in Parkinson's disease. Hum Mol Genet. 2014; 23:831-841. doi: 10.1093/hmg/ddt465 PMID: 24057672
-
(2014)
Hum Mol Genet
, vol.23
, pp. 831-841
-
-
Nalls, M.A.1
Saad, M.2
Noyce, A.J.3
Keller, M.F.4
Schrag, A.5
Bestwick, J.P.6
-
70
-
-
84906808322
-
MicroRNA-137 regulates a glucocorticoid receptor-dependent signalling network: Implications for the etiology of schizophrenia
-
PMID: 24866554
-
Valles A, Martens GJ, De Weerd P, Poelmans G, Aschrafi A. MicroRNA-137 regulates a glucocorticoid receptor-dependent signalling network: implications for the etiology of schizophrenia. J Psychiatry Neurosci. 2014; 39:312-320. PMID: 24866554
-
(2014)
J Psychiatry Neurosci
, vol.39
, pp. 312-320
-
-
Valles, A.1
Martens, G.J.2
De Weerd, P.3
Poelmans, G.4
Aschrafi, A.5
-
71
-
-
80054025163
-
MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid beta, novel targets in sporadic Alzheimer's disease
-
PMID: 21994399
-
Geekiyanage H, Chan C. MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid beta, novel targets in sporadic Alzheimer's disease. J Neurosci. 2011; 31:14820-14830. doi: 10. 1523/JNEUROSCI.3883-11.2011 PMID: 21994399
-
(2011)
J Neurosci
, vol.31
, pp. 14820-14830
-
-
Geekiyanage, H.1
Chan, C.2
-
72
-
-
84926178115
-
Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling
-
PMID: 25813876
-
Gao S, Duan C, Gao G., Wang X, Yang H. Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling. Int J BiochemCell Biol. 2015; 64:25-33. doi: 10.1016/j.biocel.2015.03.006 PMID: 25813876
-
(2015)
Int J BiochemCell Biol
, vol.64
, pp. 25-33
-
-
Gao, S.1
Duan, C.2
Gao, G.3
Wang, X.4
Yang, H.5
-
73
-
-
84876171302
-
A-synuclein protects neurons from apoptosis downstream of free-radical production through modulation of the MAPK signalling pathway
-
PMID: 22936601
-
Musgrove RE, King AE, Dickson TC a-Synuclein protects neurons from apoptosis downstream of free-radical production through modulation of the MAPK signalling pathway. Neurotox Res. 2013; 23 (4):358-369. doi: 10.1007/s12640-012-9352-5 PMID: 22936601
-
(2013)
Neurotox Res.
, vol.23
, Issue.4
, pp. 358-369
-
-
Musgrove, R.E.1
King, A.E.2
Dickson, T.C.3
-
74
-
-
84866405384
-
A-synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of notch1
-
PMID: 22833673
-
Desplats P, Spencer B, Crews L, Pathel P, Morvinski-Friedmann D, Kosberg K, et al. a-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1. J Biol Chem. 2012; 287:31691-31702. doi: 10.1074/jbc.M112.354522 PMID: 22833673
-
(2012)
J Biol Chem
, vol.287
, pp. 31691-31702
-
-
Desplats, P.1
Spencer, B.2
Crews, L.3
Pathel, P.4
Morvinski-Friedmann, D.5
Kosberg, K.6
-
75
-
-
84928608814
-
Glycogen synthase kinase-3 beta (GSK-3β) signaling: Implications for Parkinson's disease
-
PMID: 25829335
-
Golpich M, Amini E, Hemmati F., Ibrahim NM, Rahmani B, Mohamed Z, et al Glycogen synthase kinase-3 beta (GSK-3β) signaling: Implications for Parkinson's disease. Pharmacol Res. 2015; 97:16-26. doi: 10.1016/j.phrs.2015.03.010 PMID: 25829335
-
(2015)
Pharmacol Res.
, vol.97
, pp. 16-26
-
-
Golpich, M.1
Amini, E.2
Hemmati, F.3
Ibrahim, N.M.4
Rahmani, B.5
Mohamed, Z.6
-
76
-
-
79951536222
-
A-synuclein negatively regulates protein kinase co expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity
-
PMID: 21307242
-
Jin H, Kanthasamy A, Ghosh A, Yang Y, Anantharam V, Kanthasamy AG. a-Synuclein negatively regulates protein kinase Co expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity. J Neurosci. 2011; 31:2035-2051. doi: 10.1523/JNEUROSCI.5634-10.2011 PMID: 21307242
-
(2011)
J Neurosci
, vol.31
, pp. 2035-2051
-
-
Jin, H.1
Kanthasamy, A.2
Ghosh, A.3
Yang, Y.4
Anantharam, V.5
Kanthasamy, A.G.6
-
77
-
-
77952327983
-
Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway
-
PMID: 20029978
-
Wu N, Joshi PR, Cepeda C, Masliah E., Levine MS. Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway. J Neurosci Res. 2010; 88:1764-1776. doi: 10. 1002/jnr.22327 PMID: 20029978
-
(2010)
J Neurosci Res.
, vol.88
, pp. 1764-1776
-
-
Wu, N.1
Joshi, P.R.2
Cepeda, C.3
Masliah, E.4
Levine, M.S.5
-
78
-
-
67449123313
-
The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a drosophila model of Parkinson's disease
-
PMID: 19457126
-
Lee FK, Wong AK, Lee Y.W., Wan OW, Chan HY, Chung KK. The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease. 2009; J Neurochem. 110:208-219. doi: 10.1111/j.1471-4159.2009.06124.x PMID: 19457126
-
(2009)
J Neurochem
, vol.110
, pp. 208-219
-
-
Lee, F.K.1
Wong, A.K.2
Lee, Y.W.3
Wan, O.W.4
Chan, H.Y.5
Chung, K.K.6
-
79
-
-
84877351078
-
TFEB-mediated autophagy rescues midbrain dopamine neurons from osynuclein toxicity
-
PMID: 23610405
-
Decressac M, Mattsson B, Weikop P., Lundblad M, Jakobsson J, Björklund A. TFEB-mediated autophagy rescues midbrain dopamine neurons from osynuclein toxicity. Proc Natl Acad Sci USA. 2013; 110: E1817-E1826. doi: 10.1073/pnas.1305623110 PMID: 23610405
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E1817-E1826
-
-
Decressac, M.1
Mattsson, B.2
Weikop, P.3
Lundblad, M.4
Jakobsson, J.5
Björklund, A.6
-
80
-
-
80052277569
-
Genetic activation of nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a drosophila model of Parkinson's disease
-
PMID: 21719443
-
Barone MC, Sykiotis GP, Bohmann D. Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease. Dis Model Mech. 2011; 4:701-707. doi: 10.1242/dmm.007575 PMID: 21719443
-
(2011)
Dis Model Mech
, vol.4
, pp. 701-707
-
-
Barone, M.C.1
Sykiotis, G.P.2
Bohmann, D.3
-
81
-
-
84924335426
-
Acalcineurin-and NFAT-dependent pathway is involved in osynuclein-induced degeneration of midbrain dopaminergic neurons
-
PMID: 25051958
-
Luo J, Sun L, Lin X., Liu G, Yu J, Parisiadou L., et al. Acalcineurin-and NFAT-dependent pathway is involved in osynuclein-induced degeneration of midbrain dopaminergic neurons. Hum Mol Genet. 2014; 23:6567-74. doi: 10.1093/hmg/ddu377 PMID: 25051958
-
(2014)
Hum Mol Genet
, vol.23
, pp. 6567-6574
-
-
Luo, J.1
Sun, L.2
Lin, X.3
Liu, G.4
Yu, J.5
Parisiadou, L.6
-
82
-
-
84890115517
-
Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1 a transcription
-
PMID: 24290359
-
Ryan SD, Dolatabadi N, Chan S.F., Zhang X., Akhtar MW, Parker J, et al. Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1 a transcription. Cell. 2013; 155:1351-1364. doi: 10.1016/j.cell.2013.11.009 PMID: 24290359
-
(2013)
Cell
, vol.155
, pp. 1351-1364
-
-
Ryan, S.D.1
Dolatabadi, N.2
Chan, S.F.3
Zhang, X.4
Akhtar, M.W.5
Parker, J.6
-
83
-
-
78649516910
-
Alterations in mGluR5 expression and signaling in lewy body disease and in transgenic models of alpha-synucleinopathy - Implications for excitotoxicity
-
PMID: 21103359
-
Price DL, Rockenstein E, Ubhi K., Phung V, MacLean-Lewis N, Askay D, et al Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy - implications for excitotoxicity. PLoSOne. 2010; 5:e14020. doi: 10.1371/journal.pone.0014020 PMID: 21103359
-
(2010)
PLoSOne
, vol.5
-
-
Price, D.L.1
Rockenstein, E.2
Ubhi, K.3
Phung, V.4
MacLean-Lewis, N.5
Askay, D.6
-
84
-
-
80054767289
-
Osynuclein promotes neuroprotection through NF-KB-mediated transcriptional regulation of protein kinase co
-
PMID: 22009151
-
Aoki R, Li YR osynuclein promotes neuroprotection through NF-KB-mediated transcriptional regulation of protein kinase Co. Sci Signal. 2011; 4:jc6. doi: 10.1126/scisignal.2002425 PMID: 22009151
-
(2011)
Sci Signal
, vol.4
, pp. jc6
-
-
Aoki, R.1
Li, Y.R.2
-
85
-
-
84869065872
-
Proteasomal inhibition as a treatment strategy for Parkinson's disease: The impact of o synucleinon nurr1
-
PMID: 23152591
-
Devine MJ. Proteasomal inhibition as a treatment strategy for Parkinson's disease: the impact of o synucleinon Nurr1. J Neurosci. 2012; 32:16071-16073. doi: 10.1523/JNEUROSCI.4224-12.2012 PMID: 23152591
-
(2012)
J Neurosci
, vol.32
, pp. 16071-16073
-
-
Devine, M.J.1
-
86
-
-
84937976589
-
Complexin-1 and foxp1 expression changes are novel brain effects of alpha-synuclein pathology
-
PMID: 25112678
-
Gispert S, Kurz A, Brehm N, Rau K, Walter M, Riess O, Auburger G. Complexin-1 and Foxp1 Expression Changes Are Novel Brain Effects of Alpha-Synuclein Pathology. Mol Neurobiol. 2015; 52:57-63. doi: 10.1007/s12035-014-8844-0 PMID: 25112678
-
(2015)
Mol Neurobiol
, vol.52
, pp. 57-63
-
-
Gispert, S.1
Kurz, A.2
Brehm, N.3
Rau, K.4
Walter, M.5
Riess, O.6
Auburger, G.7
-
87
-
-
84870687953
-
Osynuclein-induced down-regulation of nurr1 disrupts GDNF signaling in nigral dopamine neurons
-
PMID: 23220632
-
Decressac M1, Kadkhodaei B, Mattsson B, Laguna A, Perlmann T, Björklund A. oSynuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons. Sci Transl Med. 2012; 4:163ra156. doi: 10.1126/scitranslmed.3004676 PMID: 23220632
-
(2012)
Sci Transl Med.
, vol.4
-
-
Decressac, M.1
Kadkhodaei, B.2
Mattsson, B.3
Laguna, A.4
Perlmann, T.5
Björklund, A.6
-
88
-
-
1942456752
-
BDNF is induced by wildtype alpha-synuclein but not by the two mutants, A30P or A53T, in glioma cell line
-
PMID: 15110760
-
Kohno R, Sawada H, Kawamoto Y., Uemura K, Shibasaki H, Shimohama S. BDNF is induced by wildtype alpha-synuclein but not by the two mutants, A30P or A53T, in glioma cell line. Biochem Biophys Res Commun. 2004; 318:113-118. PMID: 15110760
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 113-118
-
-
Kohno, R.1
Sawada, H.2
Kawamoto, Y.3
Uemura, K.4
Shibasaki, H.5
Shimohama, S.6
-
89
-
-
84937860948
-
Nrf2 inducer and cncC overexpression attenuates neurodegeneration due to osynuclein in drosophila
-
PMID: 26008822
-
Wang B, Liu Q, Shan H, Xia C, Liu Z. Nrf2 inducer and cncC overexpression attenuates neurodegeneration due to osynuclein in Drosophila. Biochem Cell Biol. 2015; 93:351-358. doi: 10.1139/bcb-2015-0015 PMID: 26008822
-
(2015)
Biochem Cell Biol
, vol.93
, pp. 351-358
-
-
Wang, B.1
Liu, Q.2
Shan, H.3
Xia, C.4
Liu, Z.5
-
90
-
-
34347387566
-
Alpha-synuclein involvement in hippocampal synaptic plasticity: Role of NO, cGMP, cGKand CaMKII
-
PMID: 17610578
-
Liu S, Fa M, Ninan I, Trinchese F, Dauer W, Arancio O. Alpha-synuclein involvement in hippocampal synaptic plasticity: role of NO, cGMP, cGKand CaMKII. Eur J Neurosci. 2007; 25:3583-3596. PMID: 17610578
-
(2007)
Eur J Neurosci
, vol.25
, pp. 3583-3596
-
-
Liu, S.1
Fa, M.2
Ninan, I.3
Trinchese, F.4
Dauer, W.5
Arancio, O.6
-
91
-
-
84883487726
-
Extracellular alpha-synuclein induces calpain-dependentoveractivation of cyclin-dependent kinase 5 in vitro
-
PMID: 23954626
-
Czapski GA, G ssowskaM, Wilkaniec A, Cielik M, Adamczyk A. Extracellular alpha-synuclein induces calpain-dependentoveractivation of cyclin-dependent kinase 5 in vitro. FEBS Lett. 2013; 587:3135-3141. doi: 10.1016/j.febslet.2013.07.053 PMID: 23954626
-
(2013)
FEBS Lett.
, vol.587
, pp. 3135-3141
-
-
Czapski, G.A.1
Gssowska, M.2
Wilkaniec, A.3
Cielik, M.4
Adamczyk, A.5
-
92
-
-
84890263516
-
The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro
-
PMID: 24269733
-
Dulovic M, Jovanovic M, Xilouri M., Stefanis L, Harhaji-Trajkovic L, Kravic-Stevovic T, et al. The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro. Neurobiol Dis. 2014; 63:1-11. doi: 10.1016/j.nbd.2013.11.002 PMID: 24269733
-
(2014)
Neurobiol Dis
, vol.63
, pp. 1-11
-
-
Dulovic, M.1
Jovanovic, M.2
Xilouri, M.3
Stefanis, L.4
Harhaji-Trajkovic, L.5
Kravic-Stevovic, T.6
-
93
-
-
0036832421
-
Alpha-synuclein regulates neuronal survival via bcl-2 family expression and PI3/Akt kinase pathway
-
PMID: 12223445
-
Seo JH, Rah JC, Choi S.H., Shin JK, Min K, Kim HS, et al Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway. FASEBJ. 2002; 16:1826-1828. PMID: 12223445
-
(2002)
FASEBJ
, vol.16
, pp. 1826-1828
-
-
Seo, J.H.1
Rah, J.C.2
Choi, S.H.3
Shin, J.K.4
Min, K.5
Kim, H.S.6
-
94
-
-
80053613574
-
Exogenous osynuclein fibrils induce lewy body pathology leading to synaptic dysfunction and neuron death
-
PMID: 21982369
-
Volpicelli-Daley L.A., Luk KC, Patel TP, Tanik SA, Riddle DM, Stieber A, et al. Exogenous osynuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death. Neuron. 2011; 72:57-71. doi: 10.1016/j.neuron.2011.08.033 PMID: 21982369
-
(2011)
Neuron
, vol.72
, pp. 57-71
-
-
Volpicelli-Daley, L.A.1
Luk, K.C.2
Patel, T.P.3
Tanik, S.A.4
Riddle, D.M.5
Stieber, A.6
-
95
-
-
80052328932
-
Genome-wide gene-environment study identifies glutamate receptor gene GRIN2Aas a Parkinson's disease modifier gene via interaction with coffee
-
PMID: 21876681
-
Hamza TH, Chen H, Hill-Burns EM, Rhodes SL, Montimurro J, Kay DM, et al. Genome-wide gene-environment study identifies glutamate receptor gene GRIN2Aas a Parkinson's disease modifier gene via interaction with coffee. PLoS Genet. 2011; 7:e1002237. doi: 10.1371/journal.pgen.1002237 PMID: 21876681
-
(2011)
PLoS Genet.
, vol.7
-
-
Hamza, T.H.1
Chen, H.2
Hill-Burns, E.M.3
Rhodes, S.L.4
Montimurro, J.5
Kay, D.M.6
-
96
-
-
0141428772
-
GABA(B) receptor agonists reverse akinesia following intranigral or intracerebro-ventricular injection in the reserpine-treated rat
-
PMID: 12922935
-
Johnston T, Duty S. GABA(B) receptor agonists reverse akinesia following intranigral or intracerebro-ventricular injection in the reserpine-treated rat. Br J Pharmacol. 2003; 139:1480-1486. PMID: 12922935
-
(2003)
Br J Pharmacol
, vol.139
, pp. 1480-1486
-
-
Johnston, T.1
Duty, S.2
|