GABA B receptor agonists reverse akinesia following intranigral or intracerebroventricular injection in the reserpine-treated rat

British Journal of Pharmacology

Volumn 139, Issue 8, 2003, Pages 1480-1486

  Johnston, Tom ^a,b   Duty, Susan ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Akinesia; Baclofen; GABA B receptor; Globus pallidus; Parkinson's disease; Rat, reserpine; Substantia nigra pars reticulata

Indexed keywords

3 AMINOPROPYL(METHYL)PHOSPHINIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; BACLOFEN; RESERPINE;

AKINESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; GLOBUS PALLIDUS; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SUBSTANTIA NIGRA;

ANIMALS; BACLOFEN; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA AGONISTS; GABA ANTAGONISTS; GLOBUS PALLIDUS; HYPOKINESIA; INJECTIONS, INTRAVENTRICULAR; MALE; MOTOR ACTIVITY; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHINIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-B; RESERPINE; SUBSTANTIA NIGRA;

EID: 0141428772     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705372     Document Type: Article

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