Isorhynchophylline, a natural alkaloid, promotes the degradation of α-synuclein in neuronal cells via inducing autophagy

Autophagy

Volumn 8, Issue 1, 2012, Pages 98-108

  Lu, Jia Hong ^a   Tan, Jie Qiong ^b   Durairajan, Siva Sundara Kumar ^a   Liu, Liang Feng ^a   Zhang, Zhuo Hua ^b   Ma, Long ^b   Shen, Han Ming ^c   Chan, Ho Yin Edwin ^d   Li, Min ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Alpha synuclein; Autophagy; Isorhynchophylline; Neuron; Oligomers; Parkinson disease; Protein aggregates

Indexed keywords

ALPHA SYNUCLEIN; BECLIN 1; ISORHYNCHOPHYLLINE; MONOMER; OLIGOMER; OXINDOLE;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DROSOPHILA; DRUG STRUCTURE; HUMAN; HUMAN CELL; LYSOSOME; MOUSE; NERVE CELL; NONHUMAN; PARKINSON DISEASE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; UNCARIA RHYNCHOPHYLLA; WILD TYPE;

CARANGIDAE; UNCARIA RHYNCHOPHYLLA;

EID: 84863012020     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.8.1.18313     Document Type: Article

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