α-synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity

Journal of Neuroscience

Volumn 31, Issue 6, 2011, Pages 2035-2051

  Jin, Huajun ^a   Kanthasamy, Arthi ^a   Ghosh, Anamitra ^a   Yang, Yongjie ^b   Anantharam, Vellareddy ^a   Kanthasamy, Anumantha G ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; DNA; HISTONE ACETYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN KINASE C DELTA; PROTEIN P300;

ACETYLATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; DOPAMINERGIC NERVE CELL; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MALE; MOUSE; NEUROPHYSIOLOGY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; RNA STABILITY; STABLE EXPRESSION; TRANSACTIVATION; TRANSGENIC MOUSE; WILD TYPE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ALPHA-SYNUCLEIN; ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; COMPUTATIONAL BIOLOGY; DOPAMINE; DOPAMINE AGENTS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; L-LACTATE DEHYDROGENASE; MICE; MICE, TRANSGENIC; NEURONS; P300-CBP TRANSCRIPTION FACTORS; PROTEIN KINASE C-DELTA; RATS; RNA, MESSENGER; RNA, SMALL INTERFERING; SUBSTANTIA NIGRA; TRANSFECTION; TYROSINE 3-MONOOXYGENASE;

EID: 79951536222     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5634-10.2011     Document Type: Article

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