Key interactions of surfactants in therapeutic protein formulations: A review

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 97, Issue , 2015, Pages 60-67

  Khan, Tarik A ^a,b   Mahler, Hanns Christian ^a   Kishore, Ravuri S K ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Poloxamer; Polysorbates; Protein formulations; Stabilization; Surfactants

Indexed keywords

NONIONIC SURFACTANT; POLOXAMER; POLYSORBATE 20; POLYSORBATE 80; PROTEIN DERIVATIVE; PROTEIN; SURFACTANT;

ADSORPTION; COMPLEX FORMATION; DRUG FORMULATION; DRUG STABILITY; PROTEIN INTERACTION; REVIEW; BIOLOGICAL THERAPY; CHEMISTRY; HUMAN; MEDICINAL CHEMISTRY; PROCEDURES;

BIOLOGICAL THERAPY; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; HUMANS; PROTEINS; SURFACE-ACTIVE AGENTS;

EID: 84945199873     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.09.016     Document Type: Review

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