Macromolecular crowding: Qualitative and semiquantitative successes, quantitative challenges

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1649, Issue 2, 2003, Pages 127-139

  Hall, Damien ^a   Minton, Allen P ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Excluded volume; Macromolecular solution; Thermodynamic nonideality

Indexed keywords

CHEMICAL INTERACTION; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); LIQUID CULTURE; MACROMOLECULE; MATHEMATICAL ANALYSIS; MOLECULAR MECHANICS; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVIEW; CHEMISTRY; OSMOTIC PRESSURE; PARTICLE SIZE; PROTEIN FOLDING; SOLUTION AND SOLUBILITY; THEORETICAL MODEL; THERMODYNAMICS;

DNA;

DNA; MACROMOLECULAR SUBSTANCES; MODELS, THEORETICAL; OSMOTIC PRESSURE; PARTICLE SIZE; PROTEIN FOLDING; SOLUTIONS; THERMODYNAMICS;

EID: 0041931122     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-9639(03)00167-5     Document Type: Review

References (40)

1. Fulton A.B. How crowded is the cytoplasm? Cell. 30:1982;345-347.
2. Zimmerman S.B., Minton A.P. Macromolecular crowding: biochemical, biophysical, and physiological consequences. Annu. Rev. Biophys. Biomol. Struct. 22:1993;27-65.
3. Minton A.P. Implications of macromolecular crowding for protein assembly. Curr. Opin. Struct. Biol. 10:2000;34-39.
4. Ellis R.J. Macromolecular crowding: an important, but neglected aspect of the intracellular environment. Curr. Opin. Struct. Biol. 11:2001;114-119.
5. Ellis R.J. Macromolecular crowding: obvious but underappreciated. Trends Biochem. Sci. 26:2001;597-604.
6. Al-Habori M. Macromolecular crowding and its role as intracellular signalling of cell volume regulation. Int. J. Biochem. 33:2001;844-864.
7. Minton A.P. The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media. J. Biol. Chem. 276:2001;10577-10580.
8. Minton A.P. Excluded volume as a determinant of macromolecular structure and reactivity. Biopolymers. 20:1981;2093-2120.
9. Minton A.P. The effect of volume occupancy upon the thermodynamic activity of proteins: some biochemical consequences. Mol. Cell. Biochem. 55:1983;119-140.
10. Minton A. Effects of excluded surface area and adsorbate clustering on surface adsorption of proteins: II. Kinetic models. Biophys. J. 80:2001;1641-1648.
11. Torquato S., Truskett T., Debenedetti P. Is random close packing of spheres well defined? Phys. Rev. Lett. 84:2000;2064-2067.
12. Lebowitz J.L., Helfand E., Praestgaard E. Scaled particle theory of fluid mixtures. J. Chem. Phys. 43:1965;774-779.
13. Giddings J.C., Kucera E., Russell C.P., Myers M.N. Statistical theory for the equilibrium distribution of rigid molecules in inert porous networks. Exclusion chromatography. J. Phys. Chem. 72:1968;4397-4408.
14. Minton A.P. Molecular crowding: analysis of effects of high concentrations of inert cosolutes on biochemical equilibria and rates in terms of volume exclusion. Methods Enzymol. 295:1998;127-149.
15. Laurent T.C. The interaction between polysaccharides and other macromolecules. The solubility of proteins in the presence of dextran. Biochem. J. 89:1963;253-257.
16. Ross P.D., Minton A.P. Analysis of nonideal behavior in concentrated hemoglobin solutions. J. Mol. Biol. 112:1977;437-452.
17. Minton A.P., Wilf J. Effect of macromolecular crowding upon the structure and function of an enzyme: glyceraldehyde-3-phosphate dehydrogenase. Biochemistry. 20:1981;4821-4826.
18. Luby-Phelps K. Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area. Int. Rev. Cytol. 192:2000;189-221.
19. Eisenberg D., Kauzmann W. The Structure and Properties of Water. 1969;Oxford Univ. Press, New York.
20. Berg O. The influence of macromolecular crowding on thermodynamic activity: solubility and dimerization constants for spherical and dumbbell-shaped molecules in a hard-sphere mixture. Biopolymers. 30:1990;1027-1037.
21. Minton A.P., Edelhoch H. Light scattering of bovine serum albumin solutions: extension of the hard particle model to allow for electrostatic repulsion. Biopolymers. 21:1982;451-458.
22. Minton A.P. A molecular model for the dependence of the osmotic pressure of bovine serum albumin upon concentration and pH. Biophys. Chem. 57:1995;65-70.
23. Muramatsu N., Minton A.P. Hidden self-association of proteins. J. Mol. Recognit. 1:1989;166-171.
24. McMillan W.G. Jr., Mayer J.E. The statistical thermodynamics of multicomponent systems. J. Chem. Phys. 13:1945;276-305.
25. Tanford C. Physical Chemistry of Macromolecules. 1961;Wiley, New York.
26. Ree F.H., Hoover W.G. Seventh virial coefficients for hard spheres and hard disks. J. Chem. Phys. 46:1967;4181-4192.
27. Hirschfelder J.O., Curtiss C.F., Bird R.B. Molecular Theory of Gases and Liquids. 1967;Wiley, New York.
28. Kihara T. Virial coefficients and models of molecules in gases. Rev. Mod. Phys. 25:1953;831-843.
29. Minton A.P. Influence of macromolecular crowding on intracellular association reactions: possible role in volume regulation. Strange K. Cellular and Molecular Physiology of Cell Volume Regulation. 1994;181-190 CRC Press, Boca Raton.
30. Hall D. On the role of macromolecular phase transitions in biology in response to change in solution volume or macromolecular composition: action as an entropy buffer. Biophys. Chem. 98:2002;233-248.
31. Kinjo A., Takada S. Effects of macromolecular crowding on protein folding and aggregation studied by density functional theory: statics. Phys. Rev., E. 66:2002;031911-1-031911-9.
32. Kinjo A., Takada S. Effects of macromolecular crowding on protein folding and aggregation studied by density functional theory: dynamics. Phys. Rev., E. 66:2002;051902-1-051902-10.
33. Elcock A. Atomic level observation of macromolecular crowding effects: escape of a protein from the GroEL cage. Proc. Natl. Acad. Sci. U. S. A. 100:2003;2340-2344.
34. Martin J. Requirement for GroEL/GroES-dependent protein folding under nonpermissive conditions of macromolecular crowding. Biochemistry. 41:2002;5050-5055.
35. Hatters D., Minton A.P., Howlett G.J. Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II. J. Biol. Chem. 277:2002;7824-7830.
36. Uversky V., Cooper M., Bower K., Li J., Fink A. Accelerated alpha-synuclein fibrillation in crowded milieu. FEBS Lett. 515:2002;99-103.
37. Shtilerman M., Ding T., Lansbury P.T. Molecular crowding accelerates fibrillization of alpha-synuclein: could an increase in the cytoplasmic protein concentration induce Parkinson's disease? Biochemistry. 41:2002;3855-3860.
38. Li J., Zhang S., Wang C.C. Effects of macromolecular crowding on the refolding of glucose-6-phosphate dehydrogenase and protein disulfide isomerase. J. Biol. Chem. 276:2001;34396-34401.
39. Somalinga B., Roy R. Volume exclusion effect as a driving force for reverse proteolysis. J. Biol. Chem. 277:2002;43253-43261.
40. Sasahara K., McPhie P., Minton A.P. Effect of dextran on protein stability and conformation attributed to macromolecular crowding. J. Mol. Biol. 326:2003;1227-1237.