Adsorption and function of recombinant factor VIII at the air-water interface in the presence of tween 80

Journal of Pharmaceutical Sciences

Volumn 98, Issue 9, 2009, Pages 3099-3107

  Joshi, Omkar ^a,b   Chu, Liping ^a,c   McGuire, Joseph ^a   Wang, D Q ^b  

^a 1148 Kelley Engineering Center Corvallis   (United States)

^b BAYER CORPORATION   (United States)

^c AMGEN INC   (United States)

Author keywords

Adsorption; Protein aggregation; Protein structure; Proteins; Surfactants

Indexed keywords

POLYSORBATE 80; RECOMBINANT BLOOD CLOTTING FACTOR 8;

ARTICLE; DRUG ADSORPTION; DRUG STABILITY; FLUORESCENCE SPECTROSCOPY; HUMAN; PARTIAL THROMBOPLASTIN TIME; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; SURFACE TENSION; TURBIDITY;

EID: 68949103571     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21569     Document Type: Article

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