-
1
-
-
53449086211
-
Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategies
-
Lakatos, P.L. et al. (2008) Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategies. World J. Gastroenterol., 14, 3937-3947.
-
(2008)
World J. Gastroenterol.
, vol.14
, pp. 3937-3947
-
-
Lakatos, P.L.1
-
2
-
-
0033831517
-
Infections as a major preventable cause of human cancer
-
Kuper, H. et al. (2000) Infections as a major preventable cause of human cancer. J. Intern. Med., 248, 171-183.
-
(2000)
J. Intern. Med.
, vol.248
, pp. 171-183
-
-
Kuper, H.1
-
3
-
-
84860467522
-
Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials
-
Algra, A.M. et al. (2012) Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials. Lancet Oncol., 13, 518-527.
-
(2012)
Lancet Oncol.
, vol.13
, pp. 518-527
-
-
Algra, A.M.1
-
4
-
-
64049109107
-
Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung
-
Harris, R.E. (2009) Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung. Inflammopharmacology, 17, 55-67.
-
(2009)
Inflammopharmacology
, vol.17
, pp. 55-67
-
-
Harris, R.E.1
-
5
-
-
84863412124
-
Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials
-
Rothwell, P.M. et al. (2012) Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials. Lancet, 379, 1602-1612.
-
(2012)
Lancet
, vol.379
, pp. 1602-1612
-
-
Rothwell, P.M.1
-
6
-
-
84863399038
-
Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials
-
Rothwell, P.M. et al. (2012) Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials. Lancet, 379, 1591-1601.
-
(2012)
Lancet
, vol.379
, pp. 1591-1601
-
-
Rothwell, P.M.1
-
7
-
-
33947301294
-
Immune dysfunction in inflammatory bowel disease
-
Neuman, M.G. (2007) Immune dysfunction in inflammatory bowel disease. Transl. Res., 149, 173-186.
-
(2007)
Transl. Res.
, vol.149
, pp. 173-186
-
-
Neuman, M.G.1
-
8
-
-
33847632044
-
Inflammatory bowel disease: past, present, and future
-
Sands, B.E. (2007) Inflammatory bowel disease: past, present, and future. J. Gastroenterol., 42, 16-25.
-
(2007)
J. Gastroenterol.
, vol.42
, pp. 16-25
-
-
Sands, B.E.1
-
9
-
-
33847381116
-
The fundamental basis of inflammatory bowel disease
-
Strober, W. et al. (2007) The fundamental basis of inflammatory bowel disease. J. Clin. Invest., 117, 514-521.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 514-521
-
-
Strober, W.1
-
10
-
-
38549162640
-
Inflammation, inflammatory cells and angiogenesis: decisions and indecisions
-
Noonan, D.M. et al. (2008) Inflammation, inflammatory cells and angiogenesis: decisions and indecisions. Cancer Metastasis Rev., 27, 31-40.
-
(2008)
Cancer Metastasis Rev.
, vol.27
, pp. 31-40
-
-
Noonan, D.M.1
-
11
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten, F.R. et al. (2004) IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell, 118, 285-296.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
-
12
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
Grivennikov, S. et al. (2009) IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell, 15, 103-113.
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
-
13
-
-
84876297224
-
Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases
-
Wang, K. et al. (2013). Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases. Ann. Rheum. Dis., 72 (suppl. 2), ii100-ii103.
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. ii100-ii103
-
-
Wang, K.1
-
14
-
-
84894239857
-
Role of the tumor microenvironment in the pathogenesis of gastric carcinoma
-
Chung, H.W. et al. (2014). Role of the tumor microenvironment in the pathogenesis of gastric carcinoma. World J. Gastroenterol., 20, 1667-1680.
-
(2014)
World J. Gastroenterol.
, vol.20
, pp. 1667-1680
-
-
Chung, H.W.1
-
15
-
-
84900471198
-
Peroxisome proliferator-activated receptor d promotes colonic inflammation and tumor growth
-
Wang, D. et al. (2014) Peroxisome proliferator-activated receptor d promotes colonic inflammation and tumor growth. Proc. Natl Acad. Sci. USA, 111, 7084-7089.
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 7084-7089
-
-
Wang, D.1
-
16
-
-
70449490252
-
The role of chemokines in intestinal inflammation and cancer
-
Wang, D. et al. (2009) The role of chemokines in intestinal inflammation and cancer. Curr. Opin. Pharmacol., 9, 688-696.
-
(2009)
Curr. Opin. Pharmacol.
, vol.9
, pp. 688-696
-
-
Wang, D.1
-
17
-
-
0034659767
-
Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfatemediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine
-
Andres, P.G. et al. (2000) Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfatemediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine. J. Immunol., 164, 6303-6312.
-
(2000)
J. Immunol.
, vol.164
, pp. 6303-6312
-
-
Andres, P.G.1
-
18
-
-
84887512876
-
CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis
-
Katoh, H. et al. (2013) CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis. Cancer Cell, 24, 631-644.
-
(2013)
Cancer Cell
, vol.24
, pp. 631-644
-
-
Katoh, H.1
-
19
-
-
33751071608
-
Critical role of MCP-1 in the pathogenesis of experimental colitis in the context of immune and enterochromaffin cells
-
Khan, W.I. et al. (2006) Critical role of MCP-1 in the pathogenesis of experimental colitis in the context of immune and enterochromaffin cells. Am. J. Physiol. Gastrointest. Liver Physiol., 291, G803-G811.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.291
, pp. G803-G811
-
-
Khan, W.I.1
-
20
-
-
23844499474
-
The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis
-
Tokuyama, H. et al. (2005) The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis. Int. Immunol., 17, 1023-1034.
-
(2005)
Int. Immunol.
, vol.17
, pp. 1023-1034
-
-
Tokuyama, H.1
-
21
-
-
23444437459
-
Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C
-
Horiike, S. et al. (2005) Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C. J. Hepatol., 43, 403-410.
-
(2005)
J. Hepatol.
, vol.43
, pp. 403-410
-
-
Horiike, S.1
-
22
-
-
84858116393
-
Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis
-
Murata, M. et al. (2012) Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis. J. Biomed. Biotechnol., 2012, 623019.
-
(2012)
J. Biomed. Biotechnol.
, vol.2012
, pp. 623019
-
-
Murata, M.1
-
23
-
-
0028998288
-
Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease
-
Rachmilewitz, D. et al. (1995) Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Gut, 36, 718-723.
-
(1995)
Gut
, vol.36
, pp. 718-723
-
-
Rachmilewitz, D.1
-
24
-
-
0347753322
-
Up-regulation of inducible nitric oxide synthase in Helicobacter pylori-associated gastritis may represent an increased risk factor to develop gastric carcinoma of the intestinal type
-
Rieder, G. et al. (2003) Up-regulation of inducible nitric oxide synthase in Helicobacter pylori-associated gastritis may represent an increased risk factor to develop gastric carcinoma of the intestinal type. Int. J. Med. Microbiol., 293, 403-412.
-
(2003)
Int. J. Med. Microbiol.
, vol.293
, pp. 403-412
-
-
Rieder, G.1
-
25
-
-
0346606862
-
Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease
-
Hussain, S.P. et al. (2000) Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res., 60, 3333-3337.
-
(2000)
Cancer Res.
, vol.60
, pp. 3333-3337
-
-
Hussain, S.P.1
-
26
-
-
79959743101
-
Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells
-
Gasche, J.A. et al. (2011) Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells. Int. J. Cancer, 129, 1053-1063.
-
(2011)
Int. J. Cancer
, vol.129
, pp. 1053-1063
-
-
Gasche, J.A.1
-
27
-
-
84856748026
-
Prostaglandin E2 promotes intestinal tumor growth via DNA methylation
-
Xia, D. et al. (2012) Prostaglandin E2 promotes intestinal tumor growth via DNA methylation. Nat. Med., 18, 224-226.
-
(2012)
Nat. Med.
, vol.18
, pp. 224-226
-
-
Xia, D.1
-
28
-
-
84872600554
-
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
-
Schwitalla, S. et al. (2013) Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. Cell, 152, 25-38.
-
(2013)
Cell
, vol.152
, pp. 25-38
-
-
Schwitalla, S.1
-
29
-
-
84862153001
-
New insights into chronic inflammationinduced immunosuppression
-
Kanterman, J. et al. (2012) New insights into chronic inflammationinduced immunosuppression. Semin. Cancer Biol., 22, 307-318.
-
(2012)
Semin. Cancer Biol.
, vol.22
, pp. 307-318
-
-
Kanterman, J.1
-
30
-
-
51249105349
-
Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway
-
881.e1-881.e5
-
Haile, L.A. et al. (2008) Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway. Gastroenterology, 135, 871-881, 881.e1-881.e5.
-
(2008)
Gastroenterology
, vol.135
, pp. 871-881
-
-
Haile, L.A.1
-
31
-
-
84884570755
-
Downregulation of hematopoietic MUC1 during experimental colitis increases tumor-promoting myeloid-derived suppressor cells
-
Poh, T.W. et al. (2013) Downregulation of hematopoietic MUC1 during experimental colitis increases tumor-promoting myeloid-derived suppressor cells. Clin. Cancer Res., 19, 5039-5052.
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 5039-5052
-
-
Poh, T.W.1
-
32
-
-
65249138393
-
Myeloid-derived suppressor cells: linking inflammation and cancer
-
Ostrand-Rosenberg, S. et al. (2009) Myeloid-derived suppressor cells: linking inflammation and cancer. J. Immunol., 182, 4499-4506.
-
(2009)
J. Immunol.
, vol.182
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
-
33
-
-
84889023629
-
An inflammatory mediator, prostaglandin E2, in colorectal cancer
-
Wang, D. et al. (2013) An inflammatory mediator, prostaglandin E2, in colorectal cancer. Cancer J., 19, 502-510.
-
(2013)
Cancer J.
, vol.19
, pp. 502-510
-
-
Wang, D.1
-
34
-
-
84871320421
-
Mice that express human interleukin-8 have increased mobilization of immature myeloid cells, which exacerbates inflammation and accelerates colon carcinogenesis
-
Asfaha, S. et al. (2013) Mice that express human interleukin-8 have increased mobilization of immature myeloid cells, which exacerbates inflammation and accelerates colon carcinogenesis. Gastroenterology, 144, 155-166.
-
(2013)
Gastroenterology
, vol.144
, pp. 155-166
-
-
Asfaha, S.1
-
35
-
-
54549089856
-
Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
-
Tu, S. et al. (2008) Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell, 14, 408-419.
-
(2008)
Cancer Cell
, vol.14
, pp. 408-419
-
-
Tu, S.1
-
36
-
-
37149052140
-
Special regulatory T-cell review: Regulatory T cells and the intestinal tract-patrolling the frontier
-
Izcue, A. et al. (2008) Special regulatory T-cell review: Regulatory T cells and the intestinal tract-patrolling the frontier. Immunology, 123, 6-10.
-
(2008)
Immunology
, vol.123
, pp. 6-10
-
-
Izcue, A.1
-
37
-
-
77249137663
-
Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease
-
Eastaff-Leung, N. et al. (2010) Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease. J. Clin. Immunol., 30, 80-89.
-
(2010)
J. Clin. Immunol.
, vol.30
, pp. 80-89
-
-
Eastaff-Leung, N.1
-
38
-
-
77953772080
-
Role of regulatory T-cells in H. pylori-induced gastritis and gastric cancer
-
Kandulski, A. et al. (2010) Role of regulatory T-cells in H. pylori-induced gastritis and gastric cancer. Anticancer Res., 30, 1093-1103.
-
(2010)
Anticancer Res.
, vol.30
, pp. 1093-1103
-
-
Kandulski, A.1
-
39
-
-
33750375612
-
Characterization of Foxp3+CD4+CD25+ and IL-10-secreting CD4+CD25+ T cells during cure of colitis
-
Uhlig, H.H. et al. (2006) Characterization of Foxp3+CD4+CD25+ and IL-10-secreting CD4+CD25+ T cells during cure of colitis. J. Immunol., 177, 5852-5860.
-
(2006)
J. Immunol.
, vol.177
, pp. 5852-5860
-
-
Uhlig, H.H.1
-
40
-
-
84905911071
-
In vitro induced regulatory T cells are unique from endogenous regulatory T cells and effective at suppressing late stages of ongoing autoimmunity
-
Nguyen, T.L. et al. (2014) In vitro induced regulatory T cells are unique from endogenous regulatory T cells and effective at suppressing late stages of ongoing autoimmunity. PLoS One, 9, e104698.
-
(2014)
PLoS One
, vol.9
, pp. e104698
-
-
Nguyen, T.L.1
-
41
-
-
33746525675
-
CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo
-
Rad, R. et al. (2006) CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo. Gastroenterology, 131, 525-537.
-
(2006)
Gastroenterology
, vol.131
, pp. 525-537
-
-
Rad, R.1
-
42
-
-
67650462939
-
T-regulatory cells shift from a protective antiinflammatory to a cancer-promoting proinflammatory phenotype in polyposis
-
Gounaris, E. et al. (2009) T-regulatory cells shift from a protective antiinflammatory to a cancer-promoting proinflammatory phenotype in polyposis. Cancer Res., 69, 5490-5497.
-
(2009)
Cancer Res.
, vol.69
, pp. 5490-5497
-
-
Gounaris, E.1
-
43
-
-
79952300978
-
Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases
-
Hovhannisyan, Z. et al. (2011) Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology, 140, 957-965.
-
(2011)
Gastroenterology
, vol.140
, pp. 957-965
-
-
Hovhannisyan, Z.1
-
44
-
-
79955040909
-
IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer
-
Kryczek, I. et al. (2011) IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer. J. Immunol., 186, 4388-4395.
-
(2011)
J. Immunol.
, vol.186
, pp. 4388-4395
-
-
Kryczek, I.1
-
45
-
-
77958128995
-
IL-1ß-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells
-
Li, L. et al. (2010) IL-1ß-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells. J. Immunol., 185, 4148-4153.
-
(2010)
J. Immunol.
, vol.185
, pp. 4148-4153
-
-
Li, L.1
-
46
-
-
81455135858
-
Ex vivo IL-1 receptor type I expression in human CD4+ T cells identifies an early intermediate in the differentiation of Th17 from FOXP3+ naive regulatory T cells
-
Raffin, C. et al. (2011) Ex vivo IL-1 receptor type I expression in human CD4+ T cells identifies an early intermediate in the differentiation of Th17 from FOXP3+ naive regulatory T cells. J. Immunol., 187, 5196-5202.
-
(2011)
J. Immunol.
, vol.187
, pp. 5196-5202
-
-
Raffin, C.1
-
47
-
-
84879390851
-
The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer
-
Li, L. et al. (2013) The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer. Clin. Immunol., 148, 246-253.
-
(2013)
Clin. Immunol.
, vol.148
, pp. 246-253
-
-
Li, L.1
-
48
-
-
84905976360
-
Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer
-
Pastille, E. et al. (2014) Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer. Cancer Res., 74, 4258-4269.
-
(2014)
Cancer Res.
, vol.74
, pp. 4258-4269
-
-
Pastille, E.1
-
49
-
-
44649144640
-
Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling
-
Kido, M. et al. (2008) Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling. Gastroenterology, 135, 1333-1343.
-
(2008)
Gastroenterology
, vol.135
, pp. 1333-1343
-
-
Kido, M.1
-
50
-
-
84878168812
-
Interleukin-21 and tumor necrosis factor-a are critical for the development of autoimmune gastritis in mice
-
Nishiura, H. et al. (2013) Interleukin-21 and tumor necrosis factor-a are critical for the development of autoimmune gastritis in mice. J. Gastroenterol. Hepatol., 28, 982-991.
-
(2013)
J. Gastroenterol. Hepatol.
, vol.28
, pp. 982-991
-
-
Nishiura, H.1
-
51
-
-
61449267507
-
Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade
-
Reynoso, E.D. et al. (2009) Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade. J. Immunol., 182, 2102-2112.
-
(2009)
J. Immunol.
, vol.182
, pp. 2102-2112
-
-
Reynoso, E.D.1
-
52
-
-
58149191881
-
The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands
-
Kinter, A.L. et al. (2008) The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands. J. Immunol., 181, 6738-6746.
-
(2008)
J. Immunol.
, vol.181
, pp. 6738-6746
-
-
Kinter, A.L.1
-
53
-
-
2142711024
-
The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells
-
Nakazawa, A. et al. (2004) The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells. Gastroenterology, 126, 1347-1357.
-
(2004)
Gastroenterology
, vol.126
, pp. 1347-1357
-
-
Nakazawa, A.1
-
54
-
-
77955761260
-
Increased programmed death-ligand-1 expression in human gastric epithelial cells in Helicobacter pylori infection
-
Wu, Y.Y. et al. (2010) Increased programmed death-ligand-1 expression in human gastric epithelial cells in Helicobacter pylori infection. Clin. Exp. Immunol., 161, 551-559.
-
(2010)
Clin. Exp. Immunol.
, vol.161
, pp. 551-559
-
-
Wu, Y.Y.1
-
55
-
-
78650428877
-
Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma
-
Berman, D. et al. (2010) Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma. Cancer Immun., 10, 11.
-
(2010)
Cancer Immun.
, vol.10
, pp. 11
-
-
Berman, D.1
-
56
-
-
33646016588
-
Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection
-
Anderson, K.M. et al. (2006) Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection. J. Immunol., 176, 5306-5313.
-
(2006)
J. Immunol.
, vol.176
, pp. 5306-5313
-
-
Anderson, K.M.1
-
57
-
-
0347319064
-
CTLA-4 blockade inhibits induction of Helicobacter pylori-associated gastritis in mice
-
Watanabe, K. et al. (2004) CTLA-4 blockade inhibits induction of Helicobacter pylori-associated gastritis in mice. Clin. Exp. Immunol., 135, 29-34.
-
(2004)
Clin. Exp. Immunol.
, vol.135
, pp. 29-34
-
-
Watanabe, K.1
-
58
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read, S. et al. (2000) Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med., 192, 295-302.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
-
59
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi, T. et al. (2000) Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med., 192, 303-310.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
-
60
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
Wing, K. et al. (2008) CTLA-4 control over Foxp3+ regulatory T cell function. Science, 322, 271-275.
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
-
61
-
-
54049125021
-
Spontaneous colitis occurrence in transgenic mice with altered B7-mediated costimulation
-
Kim, G. et al. (2008) Spontaneous colitis occurrence in transgenic mice with altered B7-mediated costimulation. J. Immunol., 181, 5278-5288.
-
(2008)
J. Immunol.
, vol.181
, pp. 5278-5288
-
-
Kim, G.1
-
62
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
-
Diaz-Montero, C.M. et al. (2009) Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol. Immunother., 58, 49-59.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 49-59
-
-
Diaz-Montero, C.M.1
-
63
-
-
84874117271
-
Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies
-
Duffy, A. et al. (2013) Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies. Cancer Immunol. Immunother., 62, 299-307.
-
(2013)
Cancer Immunol. Immunother.
, vol.62
, pp. 299-307
-
-
Duffy, A.1
-
64
-
-
80054102628
-
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
-
Gabitass, R.F. et al. (2011) Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13. Cancer Immunol. Immunother., 60, 1419-1430.
-
(2011)
Cancer Immunol. Immunother.
, vol.60
, pp. 1419-1430
-
-
Gabitass, R.F.1
-
65
-
-
70350133511
-
IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients
-
Mandruzzato, S. et al. (2009) IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients. J. Immunol., 182, 6562-6568.
-
(2009)
J. Immunol.
, vol.182
, pp. 6562-6568
-
-
Mandruzzato, S.1
-
66
-
-
84863923651
-
Increased frequency and clinical significance of myeloid-derived suppressor cells in human colorectal carcinoma
-
Sun, H.L. et al. (2012) Increased frequency and clinical significance of myeloid-derived suppressor cells in human colorectal carcinoma. World J. Gastroenterol., 18, 3303-3309.
-
(2012)
World J. Gastroenterol.
, vol.18
, pp. 3303-3309
-
-
Sun, H.L.1
-
67
-
-
84872172395
-
Increased myeloid-derived suppressor cells in gastric cancer correlate with cancer stage and plasma S100A8/A9 proinflammatory proteins
-
Wang, L. et al. (2013) Increased myeloid-derived suppressor cells in gastric cancer correlate with cancer stage and plasma S100A8/A9 proinflammatory proteins. J. Immunol., 190, 794-804.
-
(2013)
J. Immunol.
, vol.190
, pp. 794-804
-
-
Wang, L.1
-
68
-
-
84874236258
-
Circulating and tumor-infiltrating myeloidderived suppressor cells in patients with colorectal carcinoma
-
Zhang, B. et al. (2013) Circulating and tumor-infiltrating myeloidderived suppressor cells in patients with colorectal carcinoma. PLoS One, 8, e57114.
-
(2013)
PLoS One
, vol.8
, pp. e57114
-
-
Zhang, B.1
-
69
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
Gabrilovich, D.I. et al. (2012) Coordinated regulation of myeloid cells by tumours. Nat. Rev. Immunol., 12, 253-268.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 253-268
-
-
Gabrilovich, D.I.1
-
70
-
-
84884354300
-
Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2
-
Cui, T.X. et al. (2013) Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2. Immunity, 39, 611-621.
-
(2013)
Immunity
, vol.39
, pp. 611-621
-
-
Cui, T.X.1
-
71
-
-
84912561603
-
Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer
-
Di Mitri, D. et al. (2014) Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer. Nature, 515, 134-137.
-
(2014)
Nature
, vol.515
, pp. 134-137
-
-
Di Mitri, D.1
-
72
-
-
37349100945
-
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis
-
Yang, L. et al. (2008) Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell, 13, 23-35.
-
(2008)
Cancer Cell
, vol.13
, pp. 23-35
-
-
Yang, L.1
-
73
-
-
84863625224
-
A CXCL1 paracrine network links cancer chemoresistance and metastasis
-
Acharyya, S. et al. (2012) A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell, 150, 165-178.
-
(2012)
Cell
, vol.150
, pp. 165-178
-
-
Acharyya, S.1
-
74
-
-
53349099219
-
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
-
Cheng, P. et al. (2008) Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J. Exp. Med., 205, 2235-2249.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2235-2249
-
-
Cheng, P.1
-
75
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich, D.I. et al. (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol., 9, 162-174.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
-
76
-
-
84907029151
-
Noncanonical NF-kappaB activation mediates STAT3-stimulated IDO upregulation in myeloid-derived suppressor cells in breast cancer
-
Yu, J. et al. (2014) Noncanonical NF-kappaB activation mediates STAT3-stimulated IDO upregulation in myeloid-derived suppressor cells in breast cancer. J. Immunol., 193, 2574-2586.
-
(2014)
J. Immunol.
, vol.193
, pp. 2574-2586
-
-
Yu, J.1
-
77
-
-
84893357722
-
MicroRNA-155 and MicroRNA-21 promote the expansion of functional myeloid-derived suppressor cells
-
Li, L. et al. (2014) MicroRNA-155 and MicroRNA-21 promote the expansion of functional myeloid-derived suppressor cells. J. Immunol., 192, 1034-1043.
-
(2014)
J. Immunol.
, vol.192
, pp. 1034-1043
-
-
Li, L.1
-
78
-
-
34249300128
-
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
-
Sinha, P. et al. (2007) Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res., 67, 4507-4513.
-
(2007)
Cancer Res.
, vol.67
, pp. 4507-4513
-
-
Sinha, P.1
-
79
-
-
81555228400
-
Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
-
Obermajer, N. et al. (2011) Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Blood, 118, 5498-5505.
-
(2011)
Blood
, vol.118
, pp. 5498-5505
-
-
Obermajer, N.1
-
80
-
-
25844501447
-
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma
-
Rodriguez, P.C. et al. (2005) Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma. J. Exp. Med., 202, 931-939.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 931-939
-
-
Rodriguez, P.C.1
-
81
-
-
77956473075
-
COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function
-
Veltman, J.D. et al. (2010) COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function. BMC Cancer, 10, 464.
-
(2010)
BMC Cancer
, vol.10
, pp. 464
-
-
Veltman, J.D.1
-
82
-
-
84905455438
-
Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity
-
Mao, Y. et al. (2014) Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity. Clin. Cancer Res., 20, 4096-4106.
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 4096-4106
-
-
Mao, Y.1
-
83
-
-
79953324535
-
COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells
-
Fujita, M. et al. (2011) COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells. Cancer Res., 71, 2664-2674.
-
(2011)
Cancer Res.
, vol.71
, pp. 2664-2674
-
-
Fujita, M.1
-
84
-
-
0141891466
-
Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers
-
Ichihara, F. et al. (2003) Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers. Clin. Cancer Res., 9, 4404-4408.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 4404-4408
-
-
Ichihara, F.1
-
85
-
-
42149152160
-
CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer
-
Mizukami, Y. et al. (2008) CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer. Int. J. Cancer, 122, 2286-2293.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 2286-2293
-
-
Mizukami, Y.1
-
86
-
-
0037312480
-
Increase of regulatory T cells in the peripheral blood of cancer patients
-
Wolf, A.M. et al. (2003) Increase of regulatory T cells in the peripheral blood of cancer patients. Clin. Cancer Res., 9, 606-612.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 606-612
-
-
Wolf, A.M.1
-
87
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel, T.J. et al. (2004) Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med., 10, 942-949.
-
(2004)
Nat. Med.
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
-
88
-
-
33744457276
-
CD4(+)CD25 high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers
-
Kono, K. et al. (2006) CD4(+)CD25 high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers. Cancer Immunol. Immunother., 55, 1064-1071.
-
(2006)
Cancer Immunol. Immunother.
, vol.55
, pp. 1064-1071
-
-
Kono, K.1
-
89
-
-
20044363610
-
CD8+ T cell immunity against a tumor/selfantigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells
-
Antony, P.A. et al. (2005) CD8+ T cell immunity against a tumor/selfantigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells. J. Immunol., 174, 2591-2601.
-
(2005)
J. Immunol.
, vol.174
, pp. 2591-2601
-
-
Antony, P.A.1
-
90
-
-
0344153890
-
CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination
-
Casares, N. et al. (2003) CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination. J. Immunol., 171, 5931-5939.
-
(2003)
J. Immunol.
, vol.171
, pp. 5931-5939
-
-
Casares, N.1
-
91
-
-
0033168037
-
Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
-
Onizuka, S. et al. (1999) Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res., 59, 3128-3133.
-
(1999)
Cancer Res.
, vol.59
, pp. 3128-3133
-
-
Onizuka, S.1
-
92
-
-
0033571105
-
Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity
-
Shimizu, J. et al. (1999) Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J. Immunol., 163, 5211-5218.
-
(1999)
J. Immunol.
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
-
93
-
-
4644342928
-
Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
-
Turk, M.J. et al. (2004) Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J. Exp. Med., 200, 771-782.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 771-782
-
-
Turk, M.J.1
-
94
-
-
62449250053
-
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome
-
Gobert, M. et al. (2009) Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Res., 69, 2000-2009.
-
(2009)
Cancer Res.
, vol.69
, pp. 2000-2009
-
-
Gobert, M.1
-
95
-
-
80855156710
-
A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens
-
Pere, H. et al. (2011) A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens. Blood, 118, 4853-4862.
-
(2011)
Blood
, vol.118
, pp. 4853-4862
-
-
Pere, H.1
-
96
-
-
84863274470
-
Tumor-derived chemokine CCL5 enhances TGF-ß-mediated killing of CD8(+) T cells in colon cancer by T-regulatory cells
-
Chang, L.Y. et al. (2012) Tumor-derived chemokine CCL5 enhances TGF-ß-mediated killing of CD8(+) T cells in colon cancer by T-regulatory cells. Cancer Res., 72, 1092-1102.
-
(2012)
Cancer Res.
, vol.72
, pp. 1092-1102
-
-
Chang, L.Y.1
-
97
-
-
79952193038
-
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
-
Tan, W. et al. (2011) Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling. Nature, 470, 548-553.
-
(2011)
Nature
, vol.470
, pp. 548-553
-
-
Tan, W.1
-
98
-
-
25844504654
-
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation
-
Ghiringhelli, F. et al. (2005) Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation. J. Exp. Med., 202, 919-929.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 919-929
-
-
Ghiringhelli, F.1
-
99
-
-
33847337912
-
Tumor evasion of the immune system by converting CD4+CD25-T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta
-
Liu, V.C. et al. (2007) Tumor evasion of the immune system by converting CD4+CD25-T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta. J. Immunol., 178, 2883-2892.
-
(2007)
J. Immunol.
, vol.178
, pp. 2883-2892
-
-
Liu, V.C.1
-
100
-
-
33644784733
-
IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients
-
Ahmadzadeh, M. et al. (2006) IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients. Blood, 107, 2409-2414.
-
(2006)
Blood
, vol.107
, pp. 2409-2414
-
-
Ahmadzadeh, M.1
-
101
-
-
61349195299
-
Increased intratumoral FOXP3-positive regulatory immune cells during interleukin-2 treatment in metastatic renal cell carcinoma
-
Jensen, H.K. et al. (2009) Increased intratumoral FOXP3-positive regulatory immune cells during interleukin-2 treatment in metastatic renal cell carcinoma. Clin. Cancer Res., 15, 1052-1058.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 1052-1058
-
-
Jensen, H.K.1
-
102
-
-
84872593848
-
VEGFA-VEGFR pathway blockade inhibits tumor-induced regulatory T-cell proliferation in colorectal cancer
-
Terme, M. et al. (2013) VEGFA-VEGFR pathway blockade inhibits tumor-induced regulatory T-cell proliferation in colorectal cancer. Cancer Res., 73, 539-549.
-
(2013)
Cancer Res.
, vol.73
, pp. 539-549
-
-
Terme, M.1
-
103
-
-
48649095924
-
Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation
-
Muthuswamy, R. et al. (2008) Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation. Cancer Res., 68, 5972-5978.
-
(2008)
Cancer Res.
, vol.68
, pp. 5972-5978
-
-
Muthuswamy, R.1
-
104
-
-
22544436066
-
Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells
-
Baratelli, F. et al. (2005) Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J. Immunol., 175, 1483-1490.
-
(2005)
J. Immunol.
, vol.175
, pp. 1483-1490
-
-
Baratelli, F.1
-
105
-
-
20444464066
-
Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer
-
Sharma, S. et al. (2005) Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Res., 65, 5211-5220.
-
(2005)
Cancer Res.
, vol.65
, pp. 5211-5220
-
-
Sharma, S.1
-
106
-
-
80051480631
-
Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity
-
Nakanishi, M. et al. (2011) Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity. Cancer Prev. Res. (Phila.), 4, 1198-1208.
-
(2011)
Cancer Prev. Res. (Phila.)
, vol.4
, pp. 1198-1208
-
-
Nakanishi, M.1
-
107
-
-
79955591452
-
Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression
-
Soontrapa, K. et al. (2011) Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression. Proc. Natl Acad. Sci. USA, 108, 6668-6673.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 6668-6673
-
-
Soontrapa, K.1
-
108
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber, D.L. et al. (2006) Restoring function in exhausted CD8 T cells during chronic viral infection. Nature, 439, 682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
-
109
-
-
70349569569
-
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
-
Ahmadzadeh, M. et al. (2009) Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood, 114, 1537-1544.
-
(2009)
Blood
, vol.114
, pp. 1537-1544
-
-
Ahmadzadeh, M.1
-
110
-
-
66949111877
-
PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients
-
Fourcade, J. et al. (2009) PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients. J. Immunol., 182, 5240-5249.
-
(2009)
J. Immunol.
, vol.182
, pp. 5240-5249
-
-
Fourcade, J.1
-
111
-
-
70349562580
-
Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression
-
Mumprecht, S. et al. (2009) Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression. Blood, 114, 1528-1536.
-
(2009)
Blood
, vol.114
, pp. 1528-1536
-
-
Mumprecht, S.1
-
112
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion
-
Dong, H. et al. (2002) Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med., 8, 793-800.
-
(2002)
Nat. Med.
, vol.8
, pp. 793-800
-
-
Dong, H.1
-
113
-
-
0141953992
-
B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma
-
Strome, S.E. et al. (2003) B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma. Cancer Res., 63, 6501-6505.
-
(2003)
Cancer Res.
, vol.63
, pp. 6501-6505
-
-
Strome, S.E.1
-
114
-
-
84895556999
-
MiR-20b, -21, and -130b inhibit PTEN expression resulting in B7-H1 over-expression in advanced colorectal cancer
-
Zhu, J. et al. (2014) MiR-20b, -21, and -130b inhibit PTEN expression resulting in B7-H1 over-expression in advanced colorectal cancer. Hum. Immunol., 75, 348-353.
-
(2014)
Hum. Immunol.
, vol.75
, pp. 348-353
-
-
Zhu, J.1
-
115
-
-
33847611968
-
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer
-
Hamanishi, J. et al. (2007) Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer. Proc. Natl Acad. Sci. USA, 104, 3360-3365.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 3360-3365
-
-
Hamanishi, J.1
-
116
-
-
20244384862
-
Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer
-
Ohigashi, Y. et al. (2005) Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer. Clin. Cancer Res., 11, 2947-2953.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 2947-2953
-
-
Ohigashi, Y.1
-
117
-
-
84878962707
-
PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancer
-
Song, M. et al. (2013) PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancer. PLoS One, 8, e65821.
-
(2013)
PLoS One
, vol.8
, pp. e65821
-
-
Song, M.1
-
118
-
-
25144522150
-
B7-H1 glycoprotein blockade: a novel strategy to enhance immunotherapy in patients with renal cell carcinoma
-
Thompson, R.H. et al. (2005) B7-H1 glycoprotein blockade: a novel strategy to enhance immunotherapy in patients with renal cell carcinoma. Urology, 66 (suppl. 5), 10-14.
-
(2005)
Urology
, vol.66
, pp. 10-14
-
-
Thompson, R.H.1
-
119
-
-
79951838069
-
B7-H1 overexpression regulates epithelial-mesenchymal transition and accelerates carcinogenesis in skin
-
Cao, Y. et al. (2011) B7-H1 overexpression regulates epithelial-mesenchymal transition and accelerates carcinogenesis in skin. Cancer Res., 71, 1235-1243.
-
(2011)
Cancer Res.
, vol.71
, pp. 1235-1243
-
-
Cao, Y.1
-
120
-
-
84892365940
-
Checkpoint blocking antibodies in cancer immunotherapy
-
Kyi, C. et al. (2014) Checkpoint blocking antibodies in cancer immunotherapy. FEBS Lett., 588, 368-376.
-
(2014)
FEBS Lett.
, vol.588
, pp. 368-376
-
-
Kyi, C.1
-
121
-
-
84890020587
-
Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors
-
Akbay, E.A. et al. (2013) Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors. Cancer Discov., 3, 1355-1363.
-
(2013)
Cancer Discov.
, vol.3
, pp. 1355-1363
-
-
Akbay, E.A.1
-
122
-
-
84923072443
-
Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancer
-
Azuma, K. et al. (2014) Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancer. Ann. Oncol., 25, 1935-1940.
-
(2014)
Ann. Oncol.
, vol.25
, pp. 1935-1940
-
-
Azuma, K.1
-
123
-
-
33846118474
-
Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
-
Parsa, A.T. et al. (2007) Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat. Med., 13, 84-88.
-
(2007)
Nat. Med.
, vol.13
, pp. 84-88
-
-
Parsa, A.T.1
-
124
-
-
53949109360
-
TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells
-
Qian, Y. et al. (2008) TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells. Cancer Invest., 26, 816-821.
-
(2008)
Cancer Invest.
, vol.26
, pp. 816-821
-
-
Qian, Y.1
-
125
-
-
84901334642
-
Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy
-
Highfill, S.L. et al. (2014) Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy. Sci. Transl. Med., 6, 237ra67.
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 237-267
-
-
Highfill, S.L.1
|