메뉴 건너뛰기




Volumn 72, Issue 5, 2012, Pages 1092-1102

Tumor-derived chemokine CCL5 enhances TGF-β-mediated killing of CD8 + T cells in colon cancer by T-regulatory cells

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR5; RANTES; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84863274470     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-2493     Document Type: Article
Times cited : (188)

References (38)
  • 4
    • 70349423483 scopus 로고    scopus 로고
    • Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma
    • Sinicrope FA, Rego RL, Ansell SM, Knutson KL, Foster NR, Sargent DJ. Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma. Gastroenterology 2009;137:1270-9.
    • (2009) Gastroenterology , vol.137 , pp. 1270-1279
    • Sinicrope, F.A.1    Rego, R.L.2    Ansell, S.M.3    Knutson, K.L.4    Foster, N.R.5    Sargent, D.J.6
  • 5
    • 58249089749 scopus 로고    scopus 로고
    • Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer
    • Salama P, Phillips M, Grieu F, Morris M, Zeps N, Joseph D, et al. Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol 2009;27:186-92.
    • (2009) J Clin Oncol , vol.27 , pp. 186-192
    • Salama, P.1    Phillips, M.2    Grieu, F.3    Morris, M.4    Zeps, N.5    Joseph, D.6
  • 6
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T Cells and Immune Tolerance
    • DOI 10.1016/j.cell.2008.05.009, PII S0092867408006247
    • Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Regulatory T cells and immune tolerance. Cell 2008;133:775-87. (Pubitemid 351707693)
    • (2008) Cell , vol.133 , Issue.5 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 7
    • 39449126502 scopus 로고    scopus 로고
    • + regulatory T cell: A jack of all trades, master of regulation
    • DOI 10.1038/ni1572, PII NI1572
    • Tang Q, Bluestone JA. The Foxp3+regulatory T cell: a jack of all trades, master of regulation. Nat Immunol 2008;9:239-44. (Pubitemid 351267321)
    • (2008) Nature Immunology , vol.9 , Issue.3 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 9
    • 34247261531 scopus 로고    scopus 로고
    • Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
    • DOI 10.1200/JCO.2006.05.9584
    • Bates GJ, Fox SB, Han C, Leek RD, Garcia JF, Harris AL, et al. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol 2006;24:5373-80. (Pubitemid 46623168)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.34 , pp. 5373-5380
    • Bates, G.J.1    Fox, S.B.2    Han, C.3    Leek, R.D.4    Garcia, J.F.5    Harris, A.L.6    Banham, A.H.7
  • 11
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 2006;6:295-307.
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 12
    • 35548950221 scopus 로고    scopus 로고
    • Regulatory T-cell inhibition versus depletion: The right choice in cancer immunotherapy
    • DOI 10.1038/nrc2250, PII NRC2250
    • Colombo MP, Piconese S. Regulatory-T-cell inhibition versus depletion: the right choice in cancer immunotherapy. Nat Rev Cancer 2007;7:880-7. (Pubitemid 350006256)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.11 , pp. 880-887
    • Colombo, M.P.1    Piconese, S.2
  • 14
    • 54949139152 scopus 로고    scopus 로고
    • CD4+CD25+FOXP3 +regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer
    • Clarke SL, Betts GJ, Plant A, Wright KL, El-Shanawany TM, Harrop R, et al. CD4+CD25+FOXP3 +regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer. PLoS One 2006;1:e129.
    • (2006) PLoS One , vol.1
    • Clarke, S.L.1    Betts, G.J.2    Plant, A.3    Wright, K.L.4    El-Shanawany, T.M.5    Harrop, R.6
  • 15
    • 70449360735 scopus 로고    scopus 로고
    • Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma
    • Bonertz A, Weitz J, Pietsch DH, Rahbari NN, Schlude C, Ge Y, et al. Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma. J Clin Invest 2009;119:3311-21.
    • (2009) J Clin Invest , vol.119 , pp. 3311-3321
    • Bonertz, A.1    Weitz, J.2    Pietsch, D.H.3    Rahbari, N.N.4    Schlude, C.5    Ge, Y.6
  • 16
    • 77955725489 scopus 로고    scopus 로고
    • Accumulation of foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients
    • Deng L, Zhang H, Luan Y, Zhang J, Xing Q, Dong S, et al. Accumulation of foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients. Clin Cancer Res 2010;16:4105-12.
    • (2010) Clin Cancer Res , vol.16 , pp. 4105-4112
    • Deng, L.1    Zhang, H.2    Luan, Y.3    Zhang, J.4    Xing, Q.5    Dong, S.6
  • 17
    • 77952376596 scopus 로고    scopus 로고
    • Effector/memory but not naive regulatory T cells are responsible for the loss of concomitant tumor immunity
    • Lin YC, Chang LY, Huang CT, Peng HM, Dutta A, Chen TC, et al. Effector/memory but not naive regulatory T cells are responsible for the loss of concomitant tumor immunity. J Immunol 2009;182:6095-104.
    • (2009) J Immunol , vol.182 , pp. 6095-6104
    • Lin, Y.C.1    Chang, L.Y.2    Huang, C.T.3    Peng, H.M.4    Dutta, A.5    Chen, T.C.6
  • 18
    • 78149486215 scopus 로고    scopus 로고
    • A peptide inhibitor of FOXP3 impairs regulatory T cell activity and improves vaccine efficacy in mice
    • Casares N, Rudilla F, Arribillaga L, Llopiz D, Riezu-Boj JI, Lozano T, et al. A peptide inhibitor of FOXP3 impairs regulatory T cell activity and improves vaccine efficacy in mice. J Immunol 2010;185:5150-9.
    • (2010) J Immunol , vol.185 , pp. 5150-5159
    • Casares, N.1    Rudilla, F.2    Arribillaga, L.3    Llopiz, D.4    Riezu-Boj, J.I.5    Lozano, T.6
  • 19
    • 0142166426 scopus 로고    scopus 로고
    • Chemokines: Agents for the immunotherapy of cancer?
    • Homey B, Müller A, Zlotnik A. Chemokines: agents for the immunotherapy of cancer? Nat Rev Immunol 2002;2:175-84. (Pubitemid 37328764)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.3 , pp. 175-184
    • Homey, B.1    Muller, A.2    Zlotnik, A.3
  • 22
    • 47749097074 scopus 로고    scopus 로고
    • The inflammatory chemokines CCL2 and CCL5 in breast cancer
    • Soria G, Ben-Baruch A. The inflammatory chemokines CCL2 and CCL5 in breast cancer. Cancer Lett 2008;267:271-85.
    • (2008) Cancer Lett , vol.267 , pp. 271-285
    • Soria, G.1    Ben-Baruch, A.2
  • 23
    • 63149148047 scopus 로고    scopus 로고
    • Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer
    • Tan MC, Goedegebuure PS, Belt BA, Flaherty B, Sankpal N, Gillanders WE, et al. Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer. J Immunol 2009;182:1746-55.
    • (2009) J Immunol , vol.182 , pp. 1746-1755
    • Tan, M.C.1    Goedegebuure, P.S.2    Belt, B.A.3    Flaherty, B.4    Sankpal, N.5    Gillanders, W.E.6
  • 25
    • 47949104587 scopus 로고    scopus 로고
    • In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1
    • Gil-Guerrero L, Dotor J, Huibregtse IL, Casares N, López- Vázquez AB, Rudilla F, et al. In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1. J Immunol 2008;181:126-35.
    • (2008) J Immunol , vol.181 , pp. 126-135
    • Gil-Guerrero, L.1    Dotor, J.2    Huibregtse, I.L.3    Casares, N.4    López- Vázquez, A.B.5    Rudilla, F.6
  • 26
    • 42649086493 scopus 로고    scopus 로고
    • The expression of E-selectin and chemokines in the cultured human lymphatic endothelium with lipopolysaccharides
    • DOI 10.1111/j.1469-7580.2008.00892.x
    • Sawa Y, Tsuruga E. The expression of E-selectin and chemokines in the cultured human lymphatic endothelium with lipopolysaccharides. J Anat 2008;212:654-63. (Pubitemid 351593971)
    • (2008) Journal of Anatomy , vol.212 , Issue.5 , pp. 654-663
    • Sawa, Y.1    Tsuruga, E.2
  • 27
    • 33645796414 scopus 로고    scopus 로고
    • Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling
    • Ma B, Liu W, Homer RJ, Lee PJ, Coyle AJ, Lora JM, et al. Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol 2006;176:4968-78.
    • (2006) J Immunol , vol.176 , pp. 4968-4978
    • Ma, B.1    Liu, W.2    Homer, R.J.3    Lee, P.J.4    Coyle, A.J.5    Lora, J.M.6
  • 28
  • 29
    • 0035339270 scopus 로고    scopus 로고
    • A potential immune escape mechanism by melanoma cells through the activation of chemokine-induced T cell death
    • DOI 10.1016/S0960-9822(01)00199-3
    • Mellado M, de Ana AM, Moreno MC, Martínez C, Rodríguez- Frade JM. A potential immune escape mechanism by melanoma cells through the activation of chemokine-induced T cell death. Curr Biol 2001;11:691-6. (Pubitemid 32418165)
    • (2001) Current Biology , vol.11 , Issue.9 , pp. 691-696
    • Mellado, M.1    De Ana, A.M.2    Moreno, M.C.3    Martinez-A, C.4    Rodriguez-Frade, J.M.5
  • 31
    • 63149121284 scopus 로고    scopus 로고
    • Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis
    • Strauss L, Bergmann C, Whiteside TL. Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis. J Immunol 2009;182:1469-80.
    • (2009) J Immunol , vol.182 , pp. 1469-1480
    • Strauss, L.1    Bergmann, C.2    Whiteside, T.L.3
  • 32
    • 34548751273 scopus 로고    scopus 로고
    • TGF-beta in intestinal lymphoid organs contributes to the death of armed effector CD8 T cells and is associated with the absence of virus containment in rhesus macaques infected with the simian immunodeficiency virus
    • DOI 10.1038/sj.cdd.4402192, PII 4402192
    • Cumont MC, Monceaux V, Viollet L, Lay S, Parker R, Hurtrel B, et al. TGF-beta in intestinal lymphoid organs contributes to the death of armed effector CD8 T cells and is associated with the absence of virus containment in rhesus macaques infected with the simian immunodeficiency virus. Cell Death Differ 2007;14:1747-58. (Pubitemid 47423642)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.10 , pp. 1747-1758
    • Cumont, M.C.1    Monceaux, V.2    Viollet, L.3    Lay, S.4    Parker, R.5    Hurtrel, B.6    Estaquier, J.7
  • 33
    • 68249141869 scopus 로고    scopus 로고
    • Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells
    • Sanjabi S, Mosaheb MM, Flavell RA. Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells. Immunity 2009;31:131-44.
    • (2009) Immunity , vol.31 , pp. 131-144
    • Sanjabi, S.1    Mosaheb, M.M.2    Flavell, R.A.3
  • 34
    • 68249152608 scopus 로고    scopus 로고
    • Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo
    • Tinoco R, Alcalde V, Yang Y, Sauer K, Zuniga EI. Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo. Immunity 2009;31:145-57.
    • (2009) Immunity , vol.31 , pp. 145-157
    • Tinoco, R.1    Alcalde, V.2    Yang, Y.3    Sauer, K.4    Zuniga, E.I.5
  • 37
    • 33750530395 scopus 로고    scopus 로고
    • + regulatory T cells to sites of Leishmania major infection favors pathogen persistence
    • DOI 10.1084/jem.20060956
    • Yurchenko E, Tritt M, Hay V, Shevach EM, Belkaid Y, Piccirillo CA. CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence. J Exp Med 2006;203:2451-60. (Pubitemid 44664615)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.11 , pp. 2451-2460
    • Yurchenko, E.1    Tritt, M.2    Hay, V.3    Shevach, E.M.4    Belkaid, Y.5    Piccirillo, C.A.6
  • 38
    • 79251519312 scopus 로고    scopus 로고
    • Clinical use of CCR5 inhibitors in HIV and beyond
    • Gilliam BL, Riedel DJ, Redfield RR. Clinical use of CCR5 inhibitors in HIV and beyond. J Transl Med 2011;9 Suppl 1:S9.
    • (2011) J Transl Med , vol.9 , Issue.SUPPL. 1
    • Gilliam, B.L.1    Riedel, D.J.2    Redfield, R.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.