Interleukin-21 and tumor necrosis factor-α are critical for the development of autoimmune gastritis in mice

Journal of Gastroenterology and Hepatology (Australia)

Volumn 28, Issue 6, 2013, Pages 982-991

  Nishiura, Hisayo ^a   Iwamoto, Satoru ^a   Kido, Masahiro ^a   Aoki, Nobuhiro ^a   Maruoka, Ryutaro ^a   Ikeda, Aki ^a   Chiba, Tsutomu ^a   Watanabe, Norihiko ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Autoantibody production; Autoimmune gastritis; Cytokine

Indexed keywords

DEXAMETHASONE; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INTERLEUKIN 21; PARIETAL CELL ANTIBODY; PREDNISOLONE; PROGRAMMED DEATH 1 LIGAND 1; TUMOR NECROSIS FACTOR ALPHA; INTERLEUKIN DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE GASTRITIS; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE COURSE; GASTRITIS; HISTOPATHOLOGY; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; STOMACH MUCOSA; STOMACH PARIETAL CELL; THYMECTOMY; ANIMAL; BAGG ALBINO MOUSE; IMMUNOLOGY;

ANIMALS; AUTOIMMUNE DISEASES; GASTRITIS; INTERLEUKINS; MICE; MICE, INBRED BALB C; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878168812     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12144     Document Type: Article

References (26)

1. Strickland RG, Mackay IR. A reappraisal of the nature and significance of chronic atrophic gastritis. Dig. Dis. Sci. 1973; 18: 426-440.
2. Stockbrügger RW, Menon GG, Beilby JO, Mason RR, Cotton PB. Gastroscopic screening in 80 patients with pernicious anaemia. Gut 1983; 24: 1141-1147.
3. Mosbech J, Videbaek A. Mortality from and risk of gastric carcinoma among patients with pernicious anemia. BMJ 1950; 2: 390-394.
4. Alderuccio F, Sentry JW, Marshall AC, Biondo M, Toh BH. Animal models of human disease: experimental autoimmune gastritis-a model for autoimmune gastritis and pernicious anemia. Clin. Immunol. 2002; 102: 48-58.
5. Mori Y, Fukuma K, Adachi Y et al. Parietal cell autoantigens involved in neonatal thymectomy-induced murine autoimmune gastritis. Studies using monoclonal autoantibodies. Gastroenterology 1989; 97: 364-375.
6. Jones CM, Callaghan JM, Gleeson PA, Mori Y, Masuda T, Toh BH. The parietal cell autoantigens recognized in neonatal thymectomy-induced murine gastritis are the alpha and beta subunits of the gastric proton pump. Gastroenterology 1991; 101: 287-294.
7. Martinelli TM, van Driel IR, Alderuccio F, Gleeson PA, Toh BH. Analysis of mononuclear cell infiltrate and cytokine production in murine autoimmune gastritis. Gastroenterology 1996; 110: 1791-1802.
8. Wall AJ, Whittingham S, Mackay IR, Ungar B. Prednisolone and gastric atrophy. Clin. Exp. Immunol. 1968; 3: 359-366.
9. Jeffries GH, Todd JE, Sleisenger MH. The effect of prednisolone on gastric mucosal histology, gastric secretion, and vitamin B12 absorption in patients with pernicious anemia. J. Clin. Invest. 1966; 45: 803-812.
10. Fukuma K, Sakaguch S, Kuribayashi K et al. Immunologic and clinical studies on murine experimental autoimmune gastritis induced by neonatal thymectomy. Gastroenterology 1988; 94: 274-283.
11. De Silva HD, Van Driel IR, La Gruta N, Toh BH, Glesson PA. CD4+ T cells, but not CD8+ T cells, are required for the development of experimental autoimmune gastritis. Immunology 1998; 93: 405-408.
12. Barrett SP, Gleeson PA, de Silva H, Toh BH, van Driel IR. Interferon-gamma is required during the initiation of an organ-specific autoimmune disease. Eur. J. Immunol. 1996; 26: 1652-1655.
13. Okazaki T, Otaka Y, Wang J et al. Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b-/-Pdcd1-/- mice. J. Exp. Med. 2005; 202: 1643-1648.
14. Kido M, Watanabe N, Okazaki T et al. Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling. Gastroenterology 2008; 135: 1333-1343.
15. Aoki N, Kido M, Iwamoto S et al. Dysregulated generation of follicular helper T cells in the spleen triggers fatal autoimmune hepatitis in mice. Gastroenterology 2011; 140: 1322-1333.
16. Iwamoto S, Kido M, Aoki N et al. IFN-γ is reciprocally involved in the concurrent development of organ-specific autoimmunity in the liver and stomach. Autoimmunity 2012; 45: 186-198.
17. Nishimura H, Okazaki T, Tanaka Y et al. Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 2001; 291: 319-322.
18. Nakae S, Saijo S, Horai R, Sudo K, Mori S, Iwakura Y. Il-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc. Natl. Acad. Sci. U. S. A. 2003; 100: 5986-5990.
19. Ohana M, Okazaki K, Oshima C et al. Inhibitory effects of Helicobacter pylori infection on murine autoimmune gastritis. Gut 2003; 52: 1102-1110.
20. Nishiura H, Kido M, Aoki N et al. Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient Mice. J. Immunol. 2012; 188: 190-197.
21. Tu E, Ang DKY, Bellingham SA et al. Both IFN-γ and IL-17 are required for the development of severe autoimmune gastritis. Eur. J. Immunol. 2012; 42: 2574-2583.
22. Ang DK, Brodnicki TC, Jordan MA et al. Two genetic loci independently confer susceptibility to autoimmune gastritis. Int. Immunol. 2007; 19: 1135-1144.
23. Biondo M, Field J, Toh BH, Alderuccio F. Prednisolone promotes remission and gastric mucosal regeneration in experimental autoimmune gastritis. J. Pathol. 2006; 209: 384-391.
24. Marshall AC, Toh BH, Alderuccio F. Tumor necrosis factor alpha is not implicated in the genesis of experimental autoimmune gastritis. J. Autoimmun. 2004; 22: 1-11.
25. Marshall AC, Alderuccio F, Toh BH. Fas/CD95 is required for gastric mucosal damage in autoimmune gastritis. Gastroenterology 2002; 123: 780-789.
26. Spolski R, Leonard WJ. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 2008; 26: 57-79.