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Volumn 43, Issue 3, 2005, Pages 403-410

Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C

Author keywords

8 Hydroxy 2 deoxyguanosine; 8 Nitroguanine; Chronic hepatitis C; Hepatitis C virus; Immunohistochemistry; Interferon; Nitrative DNA damage; Oxidative DNA damage

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BIOLOGICAL MARKER; INTERFERON;

EID: 23444437459     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2005.03.026     Document Type: Article
Times cited : (52)

References (52)
  • 3
    • 0025732215 scopus 로고
    • Mutational hotspot in the p53 gene in human hepatocellular carcinoma
    • I.C. Hsu, R.A. Metcalf, T. Sun, J.A. Welsh, N.J. Wang, and C.C. Harris Mutational hotspot in the p53 gene in human hepatocellular carcinoma Nature 350 1991 427 428
    • (1991) Nature , vol.350 , pp. 427-428
    • Hsu, I.C.1    Metcalf, R.A.2    Sun, T.3    Welsh, J.A.4    Wang, N.J.5    Harris, C.C.6
  • 4
    • 0025828517 scopus 로고
    • Selective G to T mutations of p53 gene in hepatocellular carcinoma from Southern Africa
    • B. Bressac, M. Kew, J. Wands, and M. Ozturk Selective G to T mutations of p53 gene in hepatocellular carcinoma from Southern Africa Nature 350 1991 429 431
    • (1991) Nature , vol.350 , pp. 429-431
    • Bressac, B.1    Kew, M.2    Wands, J.3    Ozturk, M.4
  • 5
  • 6
    • 0029791851 scopus 로고    scopus 로고
    • Hepatitis C virus infection as a major risk factor for hepatocellular carcinoma
    • W.H. Caselmann, and M. Alt Hepatitis C virus infection as a major risk factor for hepatocellular carcinoma J Hepatol 24 1996 61 64
    • (1996) J Hepatol , vol.24 , pp. 61-64
    • Caselmann, W.H.1    Alt, M.2
  • 7
    • 0021769722 scopus 로고
    • Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents
    • H. Kasai, and S. Nishimura Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents Nucleic Acids Res 12 1984 2137 2145
    • (1984) Nucleic Acids Res , vol.12 , pp. 2137-2145
    • Kasai, H.1    Nishimura, S.2
  • 8
    • 0033461147 scopus 로고    scopus 로고
    • Oxidative DNA damage in circulating leukocytes occurs as an early event in chronic HCV infection
    • F. Farinati, R. Cardin, P. Degan, N. De Maria, F. Robert, and H.T. David Oxidative DNA damage in circulating leukocytes occurs as an early event in chronic HCV infection Free Radic Biol Med 27 1999 1284 1291
    • (1999) Free Radic Biol Med , vol.27 , pp. 1284-1291
    • Farinati, F.1    Cardin, R.2    Degan, P.3    De Maria, N.4    Robert, F.5    David, H.T.6
  • 9
    • 0031662938 scopus 로고    scopus 로고
    • Helicobacter pylori infection, oxidative DNA damage, gastric carcinogenesis, and reversibility by rebamipide
    • K.B. Hahm, K.J. Lee, J.H. Kim, S.W. Cho, and M.H. Chung Helicobacter pylori infection, oxidative DNA damage, gastric carcinogenesis, and reversibility by rebamipide Dig Dis Sci 43 1998 72 77
    • (1998) Dig Dis Sci , vol.43 , pp. 72-77
    • Hahm, K.B.1    Lee, K.J.2    Kim, J.H.3    Cho, S.W.4    Chung, M.H.5
  • 10
    • 0031469841 scopus 로고    scopus 로고
    • Analysis of a form of oxidative DNA damage, 8-hydroxy-2′- deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis
    • H. Kasai Analysis of a form of oxidative DNA damage, 8-hydroxy-2′- deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis Mutat Res 387 1997 147 163
    • (1997) Mutat Res , vol.387 , pp. 147-163
    • Kasai, H.1
  • 11
    • 0028339240 scopus 로고
    • Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human liver with chronic hepatitis
    • R. Shimoda, M. Nagashima, M. Sakamoto, N. Yamaguchi, S. Hirohashi, and J. Yokota Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human liver with chronic hepatitis Cancer Res 54 1994 3171 3172
    • (1994) Cancer Res , vol.54 , pp. 3171-3172
    • Shimoda, R.1    Nagashima, M.2    Sakamoto, M.3    Yamaguchi, N.4    Hirohashi, S.5    Yokota, J.6
  • 12
    • 0035055699 scopus 로고    scopus 로고
    • DNA oxidative damage in leukocytes correlates with the severity of HCV-ralated liver disease: Validation in an open population study
    • R. Cardin, G. Saccoccio, F. Masutti, S. Bellentani, F. Farinati, and C. Tiribelli DNA oxidative damage in leukocytes correlates with the severity of HCV-ralated liver disease: validation in an open population study J Hepatol 34 2001 587 592
    • (2001) J Hepatol , vol.34 , pp. 587-592
    • Cardin, R.1    Saccoccio, G.2    Masutti, F.3    Bellentani, S.4    Farinati, F.5    Tiribelli, C.6
  • 13
    • 0035175467 scopus 로고    scopus 로고
    • In situ detection of oxidative DNA damage, 8-hydroxydeoxyguanosine, in chronic human liver disease
    • T. Kitada, S. Seki, S. Iwai, T. Yamada, H. Sakaguti, and K. Wakasa In situ detection of oxidative DNA damage, 8-hydroxydeoxyguanosine, in chronic human liver disease J Hepatol 35 2001 613 618
    • (2001) J Hepatol , vol.35 , pp. 613-618
    • Kitada, T.1    Seki, S.2    Iwai, S.3    Yamada, T.4    Sakaguti, H.5    Wakasa, K.6
  • 14
    • 0042062310 scopus 로고    scopus 로고
    • Chemical basis of inflammation-induced carcinogenesis
    • H. Ohshima, M. Tatemichi, and T. Sawa Chemical basis of inflammation-induced carcinogenesis Arch Biochem Biophys 417 2003 3 11
    • (2003) Arch Biochem Biophys , vol.417 , pp. 3-11
    • Ohshima, H.1    Tatemichi, M.2    Sawa, T.3
  • 16
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • L.M. Coussens, and Z. Werb Inflammation and cancer Nature 420 2002 860 867
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 17
    • 0001551846 scopus 로고    scopus 로고
    • Perspective series: Nitric oxide and nitric oxide synthases
    • N. Carl Perspective series: nitric oxide and nitric oxide synthases J Clin Invest 100 1997 2417 2423
    • (1997) J Clin Invest , vol.100 , pp. 2417-2423
    • Carl, N.1
  • 18
    • 0033653531 scopus 로고    scopus 로고
    • Nitric oxide and virus infection
    • T. Akaike, and H. Maeda Nitric oxide and virus infection Immunology 101 2000 300 308
    • (2000) Immunology , vol.101 , pp. 300-308
    • Akaike, T.1    Maeda, H.2
  • 19
    • 0034906314 scopus 로고    scopus 로고
    • Coexpression of inducible nitric oxide synthase and COX-2 in hepatocellular carcinoma and surrounding liver: Possible involvement of COX-2 in angiogenesis of hepatitis C virus-positive cases
    • M.A. Rahman, D.K. Dhar, E. Yamaguchi, S. Maruyama, T. Sato, and H. Hayashi Coexpression of inducible nitric oxide synthase and COX-2 in hepatocellular carcinoma and surrounding liver: possible involvement of COX-2 in angiogenesis of hepatitis C virus-positive cases Clin Cancer Res 7 2001 1325 1332
    • (2001) Clin Cancer Res , vol.7 , pp. 1325-1332
    • Rahman, M.A.1    Dhar, D.K.2    Yamaguchi, E.3    Maruyama, S.4    Sato, T.5    Hayashi, H.6
  • 21
    • 0037054934 scopus 로고    scopus 로고
    • Impact of PTEN expression on the outcome of hepatitis C virus-positive cirrhotic hepatocellular carcinoma patients: Possible relationship with COX II and inducible nitric oxide synthase
    • M.A. Rahman, I.D. Kyriazanos, T. Ono, A. Yamanoi, H. Kohno, and M. Tsuchiya Impact of PTEN expression on the outcome of hepatitis C virus-positive cirrhotic hepatocellular carcinoma patients: possible relationship with COX II and inducible nitric oxide synthase Int J Cancer 100 2002 152 157
    • (2002) Int J Cancer , vol.100 , pp. 152-157
    • Rahman, M.A.1    Kyriazanos, I.D.2    Ono, T.3    Yamanoi, A.4    Kohno, H.5    Tsuchiya, M.6
  • 24
    • 4344680938 scopus 로고    scopus 로고
    • Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7, 8-dihydro-2′-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase
    • S. Pinlaor, N. Ma, Y. Hiraku, P. Yongvanit, R. Semba, and S. Oikawa Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7, 8-dihydro-2′-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase Carcinogenesis 2004 1535 1542
    • (2004) Carcinogenesis , pp. 1535-1542
    • Pinlaor, S.1    Ma, N.2    Hiraku, Y.3    Yongvanit, P.4    Semba, R.5    Oikawa, S.6
  • 25
    • 5644274281 scopus 로고    scopus 로고
    • Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: A model of inflammation-mediated carcinogenesis
    • S. Pinlaor, Y. Hiraku, N. Ma, P. Yongvanit, R. Semba, and S. Oikawa Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: a model of inflammation-mediated carcinogenesis Nitric Oxide 11 2004 175 183
    • (2004) Nitric Oxide , vol.11 , pp. 175-183
    • Pinlaor, S.1    Hiraku, Y.2    Ma, N.3    Yongvanit, P.4    Semba, R.5    Oikawa, S.6
  • 26
    • 0028235641 scopus 로고
    • Classification of chronic hepatitis: Diagnosis, grading and staging
    • V.J. Desmet, M. Gerber, J.H. Hoofnagle, M. Manns, and P.J. Scheuer Classification of chronic hepatitis: diagnosis, grading and staging Hepatology 19 1994 1513 1520
    • (1994) Hepatology , vol.19 , pp. 1513-1520
    • Desmet, V.J.1    Gerber, M.2    Hoofnagle, J.H.3    Manns, M.4    Scheuer, P.J.5
  • 27
    • 0030948596 scopus 로고    scopus 로고
    • Quantitative immunohistochemical determinations of 8-hydroxy-2′- deoxyguanosine by a monoclonal antibody N45.1: Its application to ferric nitrilotriacetate-induced renal carcinogenesis model
    • S. Toyokuni, T. Tanaka, Y. Hattori, Y. Nishiyama, A. Yoshida, and K. Uchida Quantitative immunohistochemical determinations of 8-hydroxy-2′- deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model Lab Invest 76 1997 365 374
    • (1997) Lab Invest , vol.76 , pp. 365-374
    • Toyokuni, S.1    Tanaka, T.2    Hattori, Y.3    Nishiyama, Y.4    Yoshida, A.5    Uchida, K.6
  • 28
    • 2442689142 scopus 로고    scopus 로고
    • Pulmonary surfactant protein a inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity
    • J.E. Crowther, V.K. Kutala, P. Kuppusamy, J.S. Ferguson, A.A. Beharka, and J.L. Zweier Pulmonary surfactant protein a inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity J Immunol 172 2004 6866 6874
    • (2004) J Immunol , vol.172 , pp. 6866-6874
    • Crowther, J.E.1    Kutala, V.K.2    Kuppusamy, P.3    Ferguson, J.S.4    Beharka, A.A.5    Zweier, J.L.6
  • 29
    • 2542615327 scopus 로고    scopus 로고
    • Susceptibility of murine periportal hepatocytes to hypoxia-reoxygenation: Role for NO and Kupffer cell-derived oxidants
    • H. Taniai, I.N. Hines, S. Bharwani, R.E. Maloney, Y. Nimura, and B. Gao Susceptibility of murine periportal hepatocytes to hypoxia-reoxygenation: role for NO and Kupffer cell-derived oxidants Hepatology 39 2004 1544 1552
    • (2004) Hepatology , vol.39 , pp. 1544-1552
    • Taniai, H.1    Hines, I.N.2    Bharwani, S.3    Maloney, R.E.4    Nimura, Y.5    Gao, B.6
  • 30
    • 0035109348 scopus 로고    scopus 로고
    • Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging
    • S. Kawanishi, Y. Hiraku, and S. Oikawa Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging Mutat Res 488 2001 65 76
    • (2001) Mutat Res , vol.488 , pp. 65-76
    • Kawanishi, S.1    Hiraku, Y.2    Oikawa, S.3
  • 31
    • 10744232427 scopus 로고    scopus 로고
    • Expression of 8-hydroxy-2′-deoxyguanosine in chronic liver disease and hepatocellular carcinoma
    • M. Ichiba, Y. Maeta, T. Mukoyama, T. Saeki, S. Yasui, and T. Kanbe Expression of 8-hydroxy-2′-deoxyguanosine in chronic liver disease and hepatocellular carcinoma Liver Int 23 2003 338 345
    • (2003) Liver Int , vol.23 , pp. 338-345
    • Ichiba, M.1    Maeta, Y.2    Mukoyama, T.3    Saeki, T.4    Yasui, S.5    Kanbe, T.6
  • 32
    • 0037396518 scopus 로고    scopus 로고
    • Immunohistochemical study of the relationship between 8-hydroxy-2′-deoxyguanosine levels in noncancerous region and postoperative recurrence of hepatocellular carcinoma in remnant liver
    • K. Matsumoto, Y. Satoh, H. Sugo, S. Takamori, K. Kojima, and M. Fukasawa Immunohistochemical study of the relationship between 8-hydroxy-2′- deoxyguanosine levels in noncancerous region and postoperative recurrence of hepatocellular carcinoma in remnant liver Hepatol Res 25 2003 435 441
    • (2003) Hepatol Res , vol.25 , pp. 435-441
    • Matsumoto, K.1    Satoh, Y.2    Sugo, H.3    Takamori, S.4    Kojima, K.5    Fukasawa, M.6
  • 34
    • 0035893552 scopus 로고    scopus 로고
    • Normalization of elevated hepatic 8-hydroxy-2′-deoxyguanosine levels in chronic hepatitis C patients by phlebotomy and low iron diet
    • J. Kato, M. Kobune, T. Nakamura, G. Kuroiwa, K. Takada, and R. Takimoto Normalization of elevated hepatic 8-hydroxy-2′-deoxyguanosine levels in chronic hepatitis C patients by phlebotomy and low iron diet Cancer Res 61 2001 8697 8702
    • (2001) Cancer Res , vol.61 , pp. 8697-8702
    • Kato, J.1    Kobune, M.2    Nakamura, T.3    Kuroiwa, G.4    Takada, K.5    Takimoto, R.6
  • 35
    • 0028328352 scopus 로고
    • Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells
    • A.W. Taylor-Robinson, F.Y. Liew, A. Severn, D. Xu, S.J. McSorley, and P. Garside Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells Eur J Immunol 24 1994 980 984
    • (1994) Eur J Immunol , vol.24 , pp. 980-984
    • Taylor-Robinson, A.W.1    Liew, F.Y.2    Severn, A.3    Xu, D.4    McSorley, S.J.5    Garside, P.6
  • 36
    • 0036550854 scopus 로고    scopus 로고
    • Kupffer cells protect liver from ischemia-reperfusion injury by an inducible nitric oxide synthase-dependent mechanism
    • C.M. Hsu, J.S. Wang, C.H. Liu, and L.W. Chen Kupffer cells protect liver from ischemia-reperfusion injury by an inducible nitric oxide synthase-dependent mechanism Shock 17 2002 280 285
    • (2002) Shock , vol.17 , pp. 280-285
    • Hsu, C.M.1    Wang, J.S.2    Liu, C.H.3    Chen, L.W.4
  • 37
    • 0035037447 scopus 로고    scopus 로고
    • Nitric oxide and chronic HCV and HIV infections
    • G. Lake-Bakaar, D. Sorbi, and V. Mazzoccoli Nitric oxide and chronic HCV and HIV infections Dig Dis Sci 46 2001 1072 1076
    • (2001) Dig Dis Sci , vol.46 , pp. 1072-1076
    • Lake-Bakaar, G.1    Sorbi, D.2    Mazzoccoli, V.3
  • 38
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide
    • D.A. Wink, and J.B. Michell Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide Free Radic Biol Med 25 1998 434 456
    • (1998) Free Radic Biol Med , vol.25 , pp. 434-456
    • Wink, D.A.1    Michell, J.B.2
  • 39
    • 0029111530 scopus 로고
    • Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide
    • S. Inoue, and S. Kawanishi Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide FEBS Lett 371 1995 86 88
    • (1995) FEBS Lett , vol.371 , pp. 86-88
    • Inoue, S.1    Kawanishi, S.2
  • 40
    • 0029979758 scopus 로고    scopus 로고
    • Base modification and strand breakage in isolated calf thymus DNA and in DNA from human skin epidermal keratinocytes exposed to peroxynitrite or 3-morpholinosydnonimine
    • J.P. Spencer, J. Wong, A. Jenner, O.I. Aruoma, C.E. Cross, and B. Halliwell Base modification and strand breakage in isolated calf thymus DNA and in DNA from human skin epidermal keratinocytes exposed to peroxynitrite or 3-morpholinosydnonimine Chem Res Toxicol 9 1996 1152 1158
    • (1996) Chem Res Toxicol , vol.9 , pp. 1152-1158
    • Spencer, J.P.1    Wong, J.2    Jenner, A.3    Aruoma, O.I.4    Cross, C.E.5    Halliwell, B.6
  • 42
    • 0035341318 scopus 로고    scopus 로고
    • Gaseous nitric oxide-induced 8-nitroguanine formation in human lung fibroblast cells and cell-free DNA
    • Y.S. Hsieh, H.C. Wang, T.H. Tseng, W.C. Chang, and C.J. Wang Gaseous nitric oxide-induced 8-nitroguanine formation in human lung fibroblast cells and cell-free DNA Toxicol Appl Pharmacol 172 2001 210 216
    • (2001) Toxicol Appl Pharmacol , vol.172 , pp. 210-216
    • Hsieh, Y.S.1    Wang, H.C.2    Tseng, T.H.3    Chang, W.C.4    Wang, C.J.5
  • 43
    • 0028293319 scopus 로고
    • Enzymatic repair of oxidative DNA damage
    • M.S. Satoh, and T. Lindahl Enzymatic repair of oxidative DNA damage Cancer Res 54 1994 1899 1901
    • (1994) Cancer Res , vol.54 , pp. 1899-1901
    • Satoh, M.S.1    Lindahl, T.2
  • 44
    • 0033969322 scopus 로고    scopus 로고
    • Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism
    • M. Jaiswal, N.F. LaRusso, L.J. Burgart, and G.J. Gores Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism Cancer Res 60 2000 184 190
    • (2000) Cancer Res , vol.60 , pp. 184-190
    • Jaiswal, M.1    Larusso, N.F.2    Burgart, L.J.3    Gores, G.J.4
  • 45
    • 0023015325 scopus 로고
    • Mutagenesis by apurinic/apyrimidinic sites
    • L.A. Loeb, and B.D. Preston Mutagenesis by apurinic/apyrimidinic sites Annu Rev Genet 20 1986 201 230
    • (1986) Annu Rev Genet , vol.20 , pp. 201-230
    • Loeb, L.A.1    Preston, B.D.2
  • 46
    • 0028785105 scopus 로고
    • Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination
    • V. Yermilov, J. Rubio, and H. Ohshima Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination FEBS Lett 376 1995 207 210
    • (1995) FEBS Lett , vol.376 , pp. 207-210
    • Yermilov, V.1    Rubio, J.2    Ohshima, H.3
  • 48
    • 17344369924 scopus 로고    scopus 로고
    • Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C. Osaka Liver Disease Study Group
    • A. Kasahara, N. Hayashi, K. Mochizuki, M. Takayanagi, K. Yoshioka, and S. Kakumu Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C. Osaka Liver Disease Study Group Hepatology 27 1998 1394 1402
    • (1998) Hepatology , vol.27 , pp. 1394-1402
    • Kasahara, A.1    Hayashi, N.2    Mochizuki, K.3    Takayanagi, M.4    Yoshioka, K.5    Kakumu, S.6
  • 49
    • 0343111507 scopus 로고    scopus 로고
    • Relation of interferon therapy and hepatocellular carcinoma in patients with chronic hepatitis C
    • Y. Imai, S. Kawata, S. Tamura, I. Yabuuchi, S. Noda, and M. Inada Relation of interferon therapy and hepatocellular carcinoma in patients with chronic hepatitis C Ann Intern Med 129 1998 94 99
    • (1998) Ann Intern Med , vol.129 , pp. 94-99
    • Imai, Y.1    Kawata, S.2    Tamura, S.3    Yabuuchi, I.4    Noda, S.5    Inada, M.6
  • 50
    • 0032898360 scopus 로고    scopus 로고
    • Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: A long-term observation study of 1643 patients using statistical bias correction with proportional hazard analysis
    • K. Ikeda, S. Saitoh, Y. Arase, K. Chayama, Y. Suzuki, and M. Kobayashi Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: a long-term observation study of 1643 patients using statistical bias correction with proportional hazard analysis Hepatology 29 1999 1124 1130
    • (1999) Hepatology , vol.29 , pp. 1124-1130
    • Ikeda, K.1    Saitoh, S.2    Arase, Y.3    Chayama, K.4    Suzuki, Y.5    Kobayashi, M.6
  • 51
    • 0033520109 scopus 로고    scopus 로고
    • Interferon therapy reduces the risk for hepatocellular carcinoma: National surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan
    • H. Yoshida, Y. Shiratori, M. Moriyama, Y. Arakawa, T. Ide, and M. Sata Interferon therapy reduces the risk for hepatocellular carcinoma: National surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan Ann Intern Med 131 1999 174 181
    • (1999) Ann Intern Med , vol.131 , pp. 174-181
    • Yoshida, H.1    Shiratori, Y.2    Moriyama, M.3    Arakawa, Y.4    Ide, T.5    Sata, M.6
  • 52
    • 2642512213 scopus 로고    scopus 로고
    • Accumulation of 8-nitroguanine in human gastric epithelium induced by Helicobacter pylori infection
    • N. Ma, Y. Adachi, Y. Hiraku, N. Horiki, S. Horiike, and I. Imoto Accumulation of 8-nitroguanine in human gastric epithelium induced by Helicobacter pylori infection Biochem Biophys Res Commun 319 2004 506 510
    • (2004) Biochem Biophys Res Commun , vol.319 , pp. 506-510
    • Ma, N.1    Adachi, Y.2    Hiraku, Y.3    Horiki, N.4    Horiike, S.5    Imoto, I.6


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