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Volumn 67, Issue 4, 2015, Pages 1005-1024

Regulation of the dopamine and vesicular monoamine transporters: Pharmacological targets and implications for disease

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; DOPAMINE TRANSPORTER; DOPAMINE UPTAKE INHIBITOR; ESTROGEN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; INSULIN; LOBELINE; METHAMPHETAMINE; METHYLPHENIDATE; RESERPINE; TETRABENAZINE; VESICULAR MONOAMINE TRANSPORTER; VESICULAR MONOAMINE TRANSPORTER 2; ADRENERGIC RECEPTOR AFFECTING AGENT;

EID: 84942433275     PISSN: 00316997     EISSN: 15210081     Source Type: Journal    
DOI: 10.1124/pr.114.010397     Document Type: Review
Times cited : (134)

References (284)
  • 1
    • 34548662875 scopus 로고    scopus 로고
    • Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching
    • Adkins EM, Samuvel DJ, Fog JU, Eriksen J, Jayanthi LD, Vaegter CB, Ramamoorthy S, and Gether U (2007) Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching. Biochemistry 46:10484-10497.
    • (2007) Biochemistry , vol.46 , pp. 10484-10497
    • Adkins, E.M.1    Samuvel, D.J.2    Fog, J.U.3    Eriksen, J.4    Jayanthi, L.D.5    Vaegter, C.B.6    Ramamoorthy, S.7    Gether, U.8
  • 4
    • 80053302164 scopus 로고    scopus 로고
    • Females are more vulnerable to drug abuse than males: Evidence from preclinical studies and the role of ovarian hormones
    • Anker JJ and Carroll ME (2011) Females are more vulnerable to drug abuse than males: evidence from preclinical studies and the role of ovarian hormones. Curr Top Behav Neurosci 8:73-96.
    • (2011) Curr Top Behav Neurosci , vol.8 , pp. 73-96
    • Anker, J.J.1    Carroll, M.E.2
  • 6
    • 84862118056 scopus 로고    scopus 로고
    • You are what you eat: Influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists
    • Baladi MG, Daws LC, and France CP (2012) You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists. Neuropharmacology 63:76-86.
    • (2012) Neuropharmacology , vol.63 , pp. 76-86
    • Baladi, M.G.1    Daws, L.C.2    France, C.P.3
  • 7
    • 84939208393 scopus 로고    scopus 로고
    • Eating high fat chow decreases dopamine clearance in adolescent and adult male rats but selectively enhances the locomotor stimulating effects of cocaine in adolescents
    • Baladi MG, Horton RE, Owens WA, Daws LC, and France CP (2015) Eating high fat chow decreases dopamine clearance in adolescent and adult male rats but selectively enhances the locomotor stimulating effects of cocaine in adolescents. Int J Neuropsychopharmacol 18:24.
    • (2015) Int J Neuropsychopharmacol , vol.18 , pp. 24
    • Baladi, M.G.1    Horton, R.E.2    Owens, W.A.3    Daws, L.C.4    France, C.P.5
  • 8
    • 4644357751 scopus 로고    scopus 로고
    • Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self-administration and food maintained responding in rats
    • Barrett AC, Miller JR, Dohrmann JM, and Caine SB (2004) Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self-administration and food maintained responding in rats. Neuropharmacology 47 (Suppl 1):256-273.
    • (2004) Neuropharmacology , vol.47 , pp. 256-273
    • Barrett, A.C.1    Miller, J.R.2    Dohrmann, J.M.3    Caine, S.B.4
  • 9
    • 1842506370 scopus 로고    scopus 로고
    • Methamphetamine increases dopamine transporter higher molecular weight complex formation via a dopamine- and hyperthermia-associated mechanism
    • Baucum AJ 2nd, Rau KS, Riddle EL, Hanson GR, and Fleckenstein AE (2004) Methamphetamine increases dopamine transporter higher molecular weight complex formation via a dopamine- and hyperthermia-associated mechanism. J Neurosci 24:3436-3443.
    • (2004) J Neurosci , vol.24 , pp. 3436-3443
    • Baucum, A.J.1    Rau, K.S.2    Riddle, E.L.3    Hanson, G.R.4    Fleckenstein, A.E.5
  • 10
    • 0030056223 scopus 로고    scopus 로고
    • Modification of dopamine transporter function: Effect of reactive oxygen species and dopamine
    • Berman SB, Zigmond MJ, and Hastings TG (1996) Modification of dopamine transporter function: effect of reactive oxygen species and dopamine. J Neurochem 67: 593-600.
    • (1996) J Neurochem , vol.67 , pp. 593-600
    • Berman, S.B.1    Zigmond, M.J.2    Hastings, T.G.3
  • 11
    • 84902548870 scopus 로고    scopus 로고
    • The vesicular monoamine transporter 2: An underexplored pharmacological target
    • Bernstein AI, Stout KA, and Miller GW (2014) The vesicular monoamine transporter 2: an underexplored pharmacological target. Neurochem Int 73:89-97.
    • (2014) Neurochem Int , vol.73 , pp. 89-97
    • Bernstein, A.I.1    Stout, K.A.2    Miller, G.W.3
  • 13
    • 3843062537 scopus 로고    scopus 로고
    • Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions
    • Bjerggaard C, Fog JU, Hastrup H, Madsen K, Loland CJ, Javitch JA, and Gether U (2004) Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions. J Neurosci 24:7024-7036.
    • (2004) J Neurosci , vol.24 , pp. 7024-7036
    • Bjerggaard, C.1    Fog, J.U.2    Hastrup, H.3    Madsen, K.4    Loland, C.J.5    Javitch, J.A.6    Gether, U.7
  • 16
    • 55749099180 scopus 로고    scopus 로고
    • Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker?
    • Boileau I, Rusjan P, Houle S, Wilkins D, Tong J, Selby P, Guttman M, Saint-Cyr JA, Wilson AA, and Kish SJ (2008) Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker? J Neurosci 28:9850-9856.
    • (2008) J Neurosci , vol.28 , pp. 9850-9856
    • Boileau, I.1    Rusjan, P.2    Houle, S.3    Wilkins, D.4    Tong, J.5    Selby, P.6    Guttman, M.7    Saint-Cyr, J.A.8    Wilson, A.A.9    Kish, S.J.10
  • 17
    • 0030922625 scopus 로고    scopus 로고
    • Ovariectomy and estradiol treatment affect the dopamine transporter and its gene expression in the rat brain
    • Bossé R, Rivest R, and Di Paolo T (1997) Ovariectomy and estradiol treatment affect the dopamine transporter and its gene expression in the rat brain. Brain Res Mol Brain Res 46:343-346.
    • (1997) Brain Res Mol Brain Res , vol.46 , pp. 343-346
    • Bossé, R.1    Rivest, R.2    Di Paolo, T.3
  • 18
    • 52049099133 scopus 로고    scopus 로고
    • Dopamine transporter endocytic determinants: Carboxy terminal residues critical for basal and PKC-stimulated internalization
    • Boudanova E, Navaroli DM, Stevens Z, and Melikian HE (2008) Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization. Mol Cell Neurosci 39:211-217.
    • (2008) Mol Cell Neurosci , vol.39 , pp. 211-217
    • Boudanova, E.1    Navaroli, D.M.2    Stevens, Z.3    Melikian, H.E.4
  • 21
    • 0034048662 scopus 로고    scopus 로고
    • Methamphetamine rapidly decreases vesicular dopamine uptake
    • Brown JM, Hanson GR, and Fleckenstein AE (2000) Methamphetamine rapidly decreases vesicular dopamine uptake. J Neurochem 74:2221-2223.
    • (2000) J Neurochem , vol.74 , pp. 2221-2223
    • Brown, J.M.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 22
    • 0034887711 scopus 로고    scopus 로고
    • Cocaine-induced increases in vesicular dopamine uptake: Role of dopamine receptors
    • Brown JM, Hanson GR, and Fleckenstein AE (2001a) Cocaine-induced increases in vesicular dopamine uptake: role of dopamine receptors. J Pharmacol Exp Ther 298: 1150-1153.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 1150-1153
    • Brown, J.M.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 23
    • 0035122979 scopus 로고    scopus 로고
    • Regulation of the vesicular monoamine transporter-2: A novel mechanism for cocaine and other psychostimulants
    • Brown JM, Hanson GR, and Fleckenstein AE (2001b) Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants. J Pharmacol Exp Ther 296:762-767.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 762-767
    • Brown, J.M.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 25
    • 84155165436 scopus 로고    scopus 로고
    • Increased risk of Parkinson’s disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs
    • Callaghan RC, Cunningham JK, Sykes J, and Kish SJ (2012) Increased risk of Parkinson’s disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs. Drug Alcohol Depend 120: 35-40.
    • (2012) Drug Alcohol Depend , vol.120 , pp. 35-40
    • Callaghan, R.C.1    Cunningham, J.K.2    Sykes, J.3    Kish, S.J.4
  • 26
    • 0027378581 scopus 로고
    • Dopamine D1 receptors facilitate transmitter release
    • Cameron DL and Williams JT (1993) Dopamine D1 receptors facilitate transmitter release. Nature 366:344-347.
    • (1993) Nature , vol.366 , pp. 344-347
    • Cameron, D.L.1    Williams, J.T.2
  • 28
    • 33645472930 scopus 로고    scopus 로고
    • Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse
    • Carroll FI, Howard JL, Howell LL, Fox BS, and Kuhar MJ (2006) Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse. AAPS J 8:E196-E203.
    • (2006) AAPS J , vol.8 , pp. E196-E203
    • Carroll, F.I.1    Howard, J.L.2    Howell, L.L.3    Fox, B.S.4    Kuhar, M.J.5
  • 29
    • 76249088643 scopus 로고    scopus 로고
    • A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles
    • Cartier EA, Parra LA, Baust TB, Quiroz M, Salazar G, Faundez V, Egaña L, and Torres GE (2010) A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles. J Biol Chem 285: 1957-1966.
    • (2010) J Biol Chem , vol.285 , pp. 1957-1966
    • Cartier, E.A.1    Parra, L.A.2    Baust, T.B.3    Quiroz, M.4    Salazar, G.5    Faundez, V.6    Egaña, L.7    Torres, G.E.8
  • 31
    • 28844445514 scopus 로고    scopus 로고
    • Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms
    • Cervinski MA, Foster JD, and Vaughan RA (2005). Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms. J Biol Chem 280:40442-40449.
    • (2005) J Biol Chem , vol.280 , pp. 40442-40449
    • Cervinski, M.A.1    Foster, J.D.2    Vaughan, R.A.3
  • 32
    • 33847306407 scopus 로고    scopus 로고
    • Structural and metabolic brain changes in the striatum associated with methamphetamine abuse
    • Chang L, Alicata D, Ernst T, and Volkow N (2007) Structural and metabolic brain changes in the striatum associated with methamphetamine abuse. Addiction 102 (Suppl 1):16-32.
    • (2007) Addiction , vol.102 , pp. 16-32
    • Chang, L.1    Alicata, D.2    Ernst, T.3    Volkow, N.4
  • 33
    • 0035007651 scopus 로고    scopus 로고
    • Protein kinase C-mediated functional regulation of dopamine transporter is not achieved by direct phosphorylation of the dopamine transporter protein
    • Chang MY, Lee SH, Kim JH, Lee KH, Kim YS, Son H, and Lee YS (2001) Protein kinase C-mediated functional regulation of dopamine transporter is not achieved by direct phosphorylation of the dopamine transporter protein. J Neurochem 77: 754-761.
    • (2001) J Neurochem , vol.77 , pp. 754-761
    • Chang, M.Y.1    Lee, S.H.2    Kim, J.H.3    Lee, K.H.4    Kim, Y.S.5    Son, H.6    Lee, Y.S.7
  • 34
    • 77549088608 scopus 로고    scopus 로고
    • The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: An autoradiography study
    • Chavez C, Hollaus M, Scarr E, Pavey G, Gogos A, and van den Buuse M (2010) The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: an autoradiography study. Brain Res 1321:51-59.
    • (2010) Brain Res , vol.1321 , pp. 51-59
    • Chavez, C.1    Hollaus, M.2    Scarr, E.3    Pavey, G.4    Gogos, A.5    Van Den Buuse, M.6
  • 35
    • 70349673573 scopus 로고    scopus 로고
    • Cigarette smoking is an independent risk factor for type 2 diabetes: A four-year community-based prospective study
    • Cho NH, Chan JC, Jang HC, Lim S, Kim HL, and Choi SH (2009) Cigarette smoking is an independent risk factor for type 2 diabetes: a four-year community-based prospective study. Clin Endocrinol (Oxf) 71:679-685.
    • (2009) Clin Endocrinol (Oxf) , vol.71 , pp. 679-685
    • Cho, N.H.1    Chan, J.C.2    Jang, H.C.3    Lim, S.4    Kim, H.L.5    Choi, S.H.6
  • 36
    • 78651299826 scopus 로고    scopus 로고
    • Methamphetamine alters vesicular monoamine transporter-2 function and potassium-stimulated dopamine release
    • Chu PW, Hadlock GC, Vieira-Brock P, Stout K, Hanson GR, and Fleckenstein AE (2010) Methamphetamine alters vesicular monoamine transporter-2 function and potassium-stimulated dopamine release. J Neurochem 115:325-332.
    • (2010) J Neurochem , vol.115 , pp. 325-332
    • Chu, P.W.1    Hadlock, G.C.2    Vieira-Brock, P.3    Stout, K.4    Hanson, G.R.5    Fleckenstein, A.E.6
  • 39
    • 84877075943 scopus 로고    scopus 로고
    • Amphetamine elicits opposing actions on readily releasable and reserve pools for dopamine
    • Covey DP, Juliano SA, and Garris PA (2013) Amphetamine elicits opposing actions on readily releasable and reserve pools for dopamine. PLoS One 8:e60763.
    • (2013) Plos One , vol.8
    • Covey, D.P.1    Juliano, S.A.2    Garris, P.A.3
  • 40
    • 1942468701 scopus 로고    scopus 로고
    • DAncing past the DAT at a DA synapse
    • Cragg SJ and Rice ME (2004) DAncing past the DAT at a DA synapse. Trends Neurosci 27:270-277.
    • (2004) Trends Neurosci , vol.27 , pp. 270-277
    • Cragg, S.J.1    Rice, M.E.2
  • 44
    • 0033544844 scopus 로고    scopus 로고
    • Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters
    • Daniels GM and Amara SG (1999) Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters. J Biol Chem 274:35794-35801.
    • (1999) J Biol Chem , vol.274 , pp. 35794-35801
    • Daniels, G.M.1    Amara, S.G.2
  • 48
    • 13044311308 scopus 로고
    • Uptake of tritium-labeled norepinephrine in brain and other tissues of cat in vitro
    • Dengler HJ, Spiegel HE, and Titus EO (1961) Uptake of tritium-labeled norepinephrine in brain and other tissues of cat in vitro. Science 133:1072-1073.
    • (1961) Science , vol.133 , pp. 1072-1073
    • Dengler, H.J.1    Spiegel, H.E.2    Titus, E.O.3
  • 49
    • 25644460008 scopus 로고    scopus 로고
    • Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-2-[bis-(4-fluorophenyl)methoxy]ethyl-4-(3-phenylpropyl)piperazine], and benztropine analogs
    • Desai RI, Kopajtic TA, French D, Newman AH, and Katz JL (2005a) Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-2-[bis-(4-fluorophenyl)methoxy]ethyl-4-(3-phenylpropyl)piperazine], and benztropine analogs. J Pharmacol Exp Ther 315:397-404.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 397-404
    • Desai, R.I.1    Kopajtic, T.A.2    French, D.3    Newman, A.H.4    Katz, J.L.5
  • 50
    • 14244260728 scopus 로고    scopus 로고
    • Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine
    • Desai RI, Kopajtic TA, Koffarnus M, Newman AH, and Katz JL (2005b) Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine. J Neurosci 25:1889-1893.
    • (2005) J Neurosci , vol.25 , pp. 1889-1893
    • Desai, R.I.1    Kopajtic, T.A.2    Koffarnus, M.3    Newman, A.H.4    Katz, J.L.5
  • 51
    • 0032546331 scopus 로고    scopus 로고
    • Inhibition of striatal dopamine transporter activity by 17beta-estradiol
    • Disshon KA, Boja JW, and Dluzen DE (1998) Inhibition of striatal dopamine transporter activity by 17beta-estradiol. Eur J Pharmacol 345:207-211.
    • (1998) Eur J Pharmacol , vol.345 , pp. 207-211
    • Disshon, K.A.1    Boja, J.W.2    Dluzen, D.E.3
  • 53
  • 54
    • 0242408732 scopus 로고    scopus 로고
    • Dopamine transporter as target for drug development of cocaine dependence medications
    • Dutta AK, Zhang S, Kolhatkar R, and Reith ME (2003) Dopamine transporter as target for drug development of cocaine dependence medications. Eur J Pharmacol 479:93-106.
    • (2003) Eur J Pharmacol , vol.479 , pp. 93-106
    • Dutta, A.K.1    Zhang, S.2    Kolhatkar, R.3    Reith, M.E.4
  • 56
    • 0026458380 scopus 로고
    • Expression cloning of a reserpine-sensitive vesicular monoamine transporter
    • Erickson JD, Eiden LE, and Hoffman BJ (1992) Expression cloning of a reserpine-sensitive vesicular monoamine transporter. Proc Natl Acad Sci USA 89:10993-10997.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10993-10997
    • Erickson, J.D.1    Eiden, L.E.2    Hoffman, B.J.3
  • 57
    • 0029896966 scopus 로고    scopus 로고
    • Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter
    • Erickson JD, Schafer MK, Bonner TI, Eiden LE, and Weihe E (1996) Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter. Proc Natl Acad Sci USA 93:5166-5171.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5166-5171
    • Erickson, J.D.1    Schafer, M.K.2    Bonner, T.I.3    Eiden, L.E.4    Weihe, E.5
  • 58
    • 77956234556 scopus 로고    scopus 로고
    • Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons
    • Eriksen J, Bjørn-Yoshimoto WE, Jørgensen TN, Newman AH, and Gether U (2010a) Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons. J Biol Chem 285:27289-27301.
    • (2010) J Biol Chem , vol.285 , pp. 27289-27301
    • Eriksen, J.1    Bjørn-Yoshimoto, W.E.2    Jørgensen, T.N.3    Newman, A.H.4    Gether, U.5
  • 59
    • 77749295404 scopus 로고    scopus 로고
    • Regulation of dopamine transporter function by protein-protein interactions: New discoveries and methodological challenges
    • Eriksen J, Jørgensen TN, and Gether U (2010b) Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges. J Neurochem 113:27-41.
    • (2010) J Neurochem , vol.113 , pp. 27-41
    • Eriksen, J.1    Jørgensen, T.N.2    Gether, U.3
  • 61
    • 11844260723 scopus 로고    scopus 로고
    • Lobeline attenuates methamphetamineinduced changes in vesicular monoamine transporter 2 immunoreactivity and monoamine depletions in the striatum
    • Eyerman DJ and Yamamoto BK (2005) Lobeline attenuates methamphetamineinduced changes in vesicular monoamine transporter 2 immunoreactivity and monoamine depletions in the striatum. J Pharmacol Exp Ther 312:160-169.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 160-169
    • Eyerman, D.J.1    Yamamoto, B.K.2
  • 62
    • 35248900341 scopus 로고    scopus 로고
    • A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine
    • Eyerman DJ and Yamamoto BK (2007) A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine. J Neurochem 103:1219-1227.
    • (2007) J Neurochem , vol.103 , pp. 1219-1227
    • Eyerman, D.J.1    Yamamoto, B.K.2
  • 64
    • 0036803521 scopus 로고    scopus 로고
    • Obesity-depression associations in the population
    • Faith MS, Matz PE, and Jorge MA (2002) Obesity-depression associations in the population. J Psychosom Res 53:935-942.
    • (2002) J Psychosom Res , vol.53 , pp. 935-942
    • Faith, M.S.1    Matz, P.E.2    Jorge, M.A.3
  • 65
    • 0025954066 scopus 로고
    • Ageing and Parkinson’s disease: Substantia nigra regional selectivity
    • Fearnley JM and Lees AJ (1991) Ageing and Parkinson’s disease: substantia nigra regional selectivity. Brain 114:2283-2301.
    • (1991) Brain , vol.114 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 66
    • 49749127282 scopus 로고    scopus 로고
    • Trafficking of vesicular neurotransmitter transporters
    • Fei H, Grygoruk A, Brooks ES, Chen A, and Krantz DE (2008) Trafficking of vesicular neurotransmitter transporters. Traffic 9:1425-1436.
    • (2008) Traffic , vol.9 , pp. 1425-1436
    • Fei, H.1    Grygoruk, A.2    Brooks, E.S.3    Chen, A.4    Krantz, D.E.5
  • 68
    • 0037458468 scopus 로고    scopus 로고
    • Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat
    • Figlewicz DP, Evans SB, Murphy J, Hoen M, and Baskin DG (2003) Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Res 964:107-115.
    • (2003) Brain Res , vol.964 , pp. 107-115
    • Figlewicz, D.P.1    Evans, S.B.2    Murphy, J.3    Hoen, M.4    Baskin, D.G.5
  • 69
    • 0028230437 scopus 로고
    • Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra
    • Figlewicz DP, Szot P, Chavez M, Woods SC, and Veith RC (1994) Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra. Brain Res 644:331-334.
    • (1994) Brain Res , vol.644 , pp. 331-334
    • Figlewicz, D.P.1    Szot, P.2    Chavez, M.3    Woods, S.C.4    Veith, R.C.5
  • 70
    • 0027220040 scopus 로고
    • Electrical stimulation of reward sites in the ventral tegmental area increases dopamine transmission in the nucleus accumbens of the rat
    • Fiorino DF, Coury A, Fibiger HC, and Phillips AG (1993) Electrical stimulation of reward sites in the ventral tegmental area increases dopamine transmission in the nucleus accumbens of the rat. Behav Brain Res 55:131-141.
    • (1993) Behav Brain Res , vol.55 , pp. 131-141
    • Fiorino, D.F.1    Coury, A.2    Fibiger, H.C.3    Phillips, A.G.4
  • 71
    • 0034613214 scopus 로고    scopus 로고
    • Differential effects of stimulants on monoaminergic transporters: Pharmacological consequences and implications for neurotoxicity
    • Fleckenstein AE, Gibb JW, and Hanson GR (2000) Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity. Eur J Pharmacol 406:1-13.
    • (2000) Eur J Pharmacol , vol.406 , pp. 1-13
    • Fleckenstein, A.E.1    Gibb, J.W.2    Hanson, G.R.3
  • 76
    • 0030606815 scopus 로고    scopus 로고
    • Amphetamine releases dopamine from synaptic vesicles by dual mechanisms
    • Floor E and Meng L (1996) Amphetamine releases dopamine from synaptic vesicles by dual mechanisms. Neurosci Lett 215:53-56.
    • (1996) Neurosci Lett , vol.215 , pp. 53-56
    • Floor, E.1    Meng, L.2
  • 78
    • 43549127315 scopus 로고    scopus 로고
    • Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol
    • Foster JD, Adkins SD, Lever JR, and Vaughan RA (2008) Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol. J Neurochem 105: 1683-1699.
    • (2008) J Neurochem , vol.105 , pp. 1683-1699
    • Foster, J.D.1    Adkins, S.D.2    Lever, J.R.3    Vaughan, R.A.4
  • 79
    • 0037067690 scopus 로고    scopus 로고
    • Dopamine transporters are phosphorylated on N-terminal serines in rat striatum
    • Foster JD, Pananusorn B, and Vaughan RA (2002) Dopamine transporters are phosphorylated on N-terminal serines in rat striatum. J Biol Chem 277: 25178-25186.
    • (2002) J Biol Chem , vol.277 , pp. 25178-25186
    • Foster, J.D.1    Pananusorn, B.2    Vaughan, R.A.3
  • 80
    • 79953132315 scopus 로고    scopus 로고
    • Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation
    • Foster JD and Vaughan RA (2011) Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. J Biol Chem 286:5175-5186.
    • (2011) J Biol Chem , vol.286 , pp. 5175-5186
    • Foster, J.D.1    Vaughan, R.A.2
  • 82
    • 33846856920 scopus 로고    scopus 로고
    • RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport
    • Fountaine TM and Wade-Martins R (2007) RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport. J Neurosci Res 85:351-363.
    • (2007) J Neurosci Res , vol.85 , pp. 351-363
    • Fountaine, T.M.1    Wade-Martins, R.2
  • 83
    • 77949988313 scopus 로고    scopus 로고
    • Advances in the pharmacological management of Huntington’s disease
    • Frank S and Jankovic J (2010) Advances in the pharmacological management of Huntington’s disease. Drugs 70:561-571.
    • (2010) Drugs , vol.70 , pp. 561-571
    • Frank, S.1    Jankovic, J.2
  • 85
    • 0035237282 scopus 로고    scopus 로고
    • Imaging the vesicular monoamine transporter
    • Frey KA, Koeppe RA, and Kilbourn MR (2001) Imaging the vesicular monoamine transporter. Adv Neurol 86:237-247.
    • (2001) Adv Neurol , vol.86 , pp. 237-247
    • Frey, K.A.1    Koeppe, R.A.2    Kilbourn, M.R.3
  • 86
    • 63849284330 scopus 로고    scopus 로고
    • Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: Live-cell imaging using total internal reflection fluorescence microscopy
    • Furman CA, Chen R, Guptaroy B, Zhang M, Holz RW, and Gnegy M (2009) Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy. J Neurosci 29:3328-3336.
    • (2009) J Neurosci , vol.29 , pp. 3328-3336
    • Furman, C.A.1    Chen, R.2    Guptaroy, B.3    Zhang, M.4    Holz, R.W.5    Gnegy, M.6
  • 88
    • 84867067969 scopus 로고    scopus 로고
    • Amphetamine and methamphetamine reduce striatal dopamine transporter function without concurrent dopamine transporter relocalization
    • German CL, Hanson GR, and Fleckenstein AE (2012) Amphetamine and methamphetamine reduce striatal dopamine transporter function without concurrent dopamine transporter relocalization. J Neurochem 123:288-297.
    • (2012) J Neurochem , vol.123 , pp. 288-297
    • German, C.L.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 89
    • 0030844034 scopus 로고    scopus 로고
    • Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism
    • Gill M, Daly G, Heron S, Hawi Z, and Fitzgerald M (1997) Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism. Mol Psychiatry 2:311-313.
    • (1997) Mol Psychiatry , vol.2 , pp. 311-313
    • Gill, M.1    Daly, G.2    Heron, S.3    Hawi, Z.4    Fitzgerald, M.5
  • 90
    • 77952386471 scopus 로고    scopus 로고
    • Estrogen actions in the brain and the basis for differential action in men and women: A case for sex-specific medicines
    • Gillies GE and McArthur S (2010) Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines. Pharmacol Rev 62:155-198.
    • (2010) Pharmacol Rev , vol.62 , pp. 155-198
    • Gillies, G.E.1    McArthur, S.2
  • 91
    • 0028947076 scopus 로고
    • Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: Impact of methamphetamine
    • Giovanni A, Liang LP, Hastings TG, and Zigmond MJ (1995) Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine. J Neurochem 64:1819-1825.
    • (1995) J Neurochem , vol.64 , pp. 1819-1825
    • Giovanni, A.1    Liang, L.P.2    Hastings, T.G.3    Zigmond, M.J.4
  • 92
    • 0026335164 scopus 로고
    • Cloning and functional characterization of a cocaine-sensitive dopamine transporter
    • Giros B, el Mestikawy S, Bertrand L, and Caron MG (1991) Cloning and functional characterization of a cocaine-sensitive dopamine transporter. FEBS Lett 295: 149-154.
    • (1991) FEBS Lett , vol.295 , pp. 149-154
    • Giros, B.1    El Mestikawy, S.2    Bertrand, L.3    Caron, M.G.4
  • 93
    • 0027049060 scopus 로고
    • Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
    • Giros B, el Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, and Caron MG (1992) Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. Mol Pharmacol 42:383-390.
    • (1992) Mol Pharmacol , vol.42 , pp. 383-390
    • Giros, B.1    El Mestikawy, S.2    Godinot, N.3    Zheng, K.4    Han, H.5    Yang-Feng, T.6    Caron, M.G.7
  • 94
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B, Jaber M, Jones SR, Wightman RM, and Caron MG (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379:606-612.
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 95
    • 0001930599 scopus 로고
    • Metabolism of (H3)Norepinephrine in the Rat Brain
    • Glowinski J, Kopin IJ, and Axelrod J (1965) Metabolism of (H3)Norepinephrine in the Rat Brain. J Neurochem 12:25-30.
    • (1965) J Neurochem , vol.12 , pp. 25-30
    • Glowinski, J.1    Kopin, I.J.2    Axelrod, J.3
  • 96
    • 61449170264 scopus 로고    scopus 로고
    • Proline-directed phosphorylation of the dopamine transporter N-terminal domain
    • Gorentla BK, Moritz AE, Foster JD, and Vaughan RA (2009) Proline-directed phosphorylation of the dopamine transporter N-terminal domain. Biochemistry 48: 1067-1076.
    • (2009) Biochemistry , vol.48 , pp. 1067-1076
    • Gorentla, B.K.1    Moritz, A.E.2    Foster, J.D.3    Vaughan, R.A.4
  • 99
    • 0037775994 scopus 로고    scopus 로고
    • N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptorstimulated phosphorylation without impairing transporter internalization
    • Granas C, Ferrer J, Loland CJ, Javitch JA, and Gether U (2003) N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptorstimulated phosphorylation without impairing transporter internalization. J Biol Chem 278:4990-5000.
    • (2003) J Biol Chem , vol.278 , pp. 4990-5000
    • Granas, C.1    Ferrer, J.2    Loland, C.J.3    Javitch, J.A.4    Gether, U.5
  • 102
    • 77957227921 scopus 로고    scopus 로고
    • Methamphetamine-induced dopamine transporter complex formation and dopaminergic deficits: The role of D2 receptor activation
    • Hadlock GC, Chu PW, Walters ET, Hanson GR, and Fleckenstein AE (2010) Methamphetamine-induced dopamine transporter complex formation and dopaminergic deficits: the role of D2 receptor activation. J Pharmacol Exp Ther 335: 207-212.
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 207-212
    • Hadlock, G.C.1    Chu, P.W.2    Walters, E.T.3    Hanson, G.R.4    Fleckenstein, A.E.5
  • 103
    • 77949897463 scopus 로고    scopus 로고
    • The progression of pathology in Parkinson’s disease
    • Halliday GM and McCann H (2010) The progression of pathology in Parkinson’s disease. Ann N Y Acad Sci 1184:188-195.
    • (2010) Ann N Y Acad Sci , vol.1184 , pp. 188-195
    • Halliday, G.M.1    McCann, H.2
  • 109
    • 84874102065 scopus 로고    scopus 로고
    • Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: Exploring task-specific, stimulant medication, and age effects
    • Hart H, Radua J, Nakao T, Mataix-Cols D, and Rubia K (2013) Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effects. JAMA Psychiatry 70:185-198.
    • (2013) JAMA Psychiatry , vol.70 , pp. 185-198
    • Hart, H.1    Radua, J.2    Nakao, T.3    Mataix-Cols, D.4    Rubia, K.5
  • 110
    • 0035964192 scopus 로고    scopus 로고
    • Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment
    • Hastrup H, Karlin A, and Javitch JA (2001) Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment. Proc Natl Acad Sci USA 98:10055-10060.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10055-10060
    • Hastrup, H.1    Karlin, A.2    Javitch, J.A.3
  • 111
    • 0032695406 scopus 로고    scopus 로고
    • Oxygen radicals differentially affect Na+/Cl(-)-dependent transporters
    • Haughey HM, Brown JM, Fleckenstein AE, and Hanson GR (1999) Oxygen radicals differentially affect Na+/Cl(-)-dependent transporters. Eur J Pharmacol 379: 107-110.
    • (1999) Eur J Pharmacol , vol.379 , pp. 107-110
    • Haughey, H.M.1    Brown, J.M.2    Fleckenstein, A.E.3    Hanson, G.R.4
  • 112
    • 0016796696 scopus 로고
    • Studies on the distinction between uptake inhibition and release of (3H)dopamine in rat brain tissue slices
    • Heikkila RE, Orlansky H, and Cohen G (1975) Studies on the distinction between uptake inhibition and release of (3H)dopamine in rat brain tissue slices. Biochem Pharmacol 24:847-852.
    • (1975) Biochem Pharmacol , vol.24 , pp. 847-852
    • Heikkila, R.E.1    Orlansky, H.2    Cohen, G.3
  • 113
    • 84891644551 scopus 로고    scopus 로고
    • Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats
    • Hiranita T, Kohut SJ, Soto PL, Tanda G, Kopajtic TA, and Katz JL (2014) Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats. J Pharmacol Exp Ther 348:174-191.
    • (2014) J Pharmacol Exp Ther , vol.348 , pp. 174-191
    • Hiranita, T.1    Kohut, S.J.2    Soto, P.L.3    Tanda, G.4    Kopajtic, T.A.5    Katz, J.L.6
  • 115
    • 65649118524 scopus 로고    scopus 로고
    • Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: Comparisons with monoamine uptake inhibitors
    • Hiranita T, Soto PL, Newman AH, and Katz JL (2009) Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors. J Pharmacol Exp Ther 329:677-686.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 677-686
    • Hiranita, T.1    Soto, P.L.2    Newman, A.H.3    Katz, J.L.4
  • 116
    • 0034007741 scopus 로고    scopus 로고
    • Analysis of VMAT2 binding after methamphetamine or MPTP treatment: Disparity between homogenates and vesicle preparations
    • Hogan KA, Staal RG, and Sonsalla PK (2000) Analysis of VMAT2 binding after methamphetamine or MPTP treatment: disparity between homogenates and vesicle preparations. J Neurochem 74:2217-2220.
    • (2000) J Neurochem , vol.74 , pp. 2217-2220
    • Hogan, K.A.1    Staal, R.G.2    Sonsalla, P.K.3
  • 117
    • 24944439152 scopus 로고    scopus 로고
    • Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
    • Holton KL, Loder MK, and Melikian HE (2005) Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization. Nat Neurosci 8:881-888.
    • (2005) Nat Neurosci , vol.8 , pp. 881-888
    • Holton, K.L.1    Loder, M.K.2    Melikian, H.E.3
  • 118
    • 77957791961 scopus 로고    scopus 로고
    • Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding
    • Hong WC and Amara SG (2010) Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding. J Biol Chem 285:32616-32626.
    • (2010) J Biol Chem , vol.285 , pp. 32616-32626
    • Hong, W.C.1    Amara, S.G.2
  • 119
    • 33750017421 scopus 로고    scopus 로고
    • The discovery of dopamine deficiency in the parkinsonian brain
    • Hornykiewicz O (2006) The discovery of dopamine deficiency in the parkinsonian brain. J Neural Transm Suppl 70:9-15.
    • (2006) J Neural Transm Suppl , vol.70 , pp. 9-15
    • Hornykiewicz, O.1
  • 120
    • 84893192123 scopus 로고    scopus 로고
    • Monoamine transporter inhibitors and substrates as treatments for stimulant abuse
    • Howell LL and Negus SS (2014) Monoamine transporter inhibitors and substrates as treatments for stimulant abuse. Adv Pharmacol 69:129-176.
    • (2014) Adv Pharmacol , vol.69 , pp. 129-176
    • Howell, L.L.1    Negus, S.S.2
  • 121
    • 0027008515 scopus 로고
    • Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and postsynaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus
    • Huang Q, Zhou D, Chase K, Gusella JF, Aronin N, and DiFiglia M (1992) Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and postsynaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus. Proc Natl Acad Sci USA 89: 11988-11992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11988-11992
    • Huang, Q.1    Zhou, D.2    Chase, K.3    Gusella, J.F.4    Aronin, N.5    Difiglia, M.6
  • 122
    • 0036784803 scopus 로고    scopus 로고
    • Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons
    • Ingram SL, Prasad BM, and Amara SG (2002) Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons. Nat Neurosci 5: 971-978.
    • (2002) Nat Neurosci , vol.5 , pp. 971-978
    • Ingram, S.L.1    Prasad, B.M.2    Amara, S.G.3
  • 123
    • 84898057061 scopus 로고    scopus 로고
    • Comparison of dopamine transporter decline in a patient with Parkinson’s disease and normal aging effect
    • Ishibashi K, Oda K, Ishiwata K, and Ishii K (2014) Comparison of dopamine transporter decline in a patient with Parkinson’s disease and normal aging effect. J Neurol Sci 339:207-209.
    • (2014) J Neurol Sci , vol.339 , pp. 207-209
    • Ishibashi, K.1    Oda, K.2    Ishiwata, K.3    Ishii, K.4
  • 124
    • 11144232015 scopus 로고    scopus 로고
    • Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter
    • Jiang H, Jiang Q, and Feng J (2004) Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter. J Biol Chem 279:54380-54386.
    • (2004) J Biol Chem , vol.279 , pp. 54380-54386
    • Jiang, H.1    Jiang, Q.2    Feng, J.3
  • 126
    • 26944458499 scopus 로고    scopus 로고
    • Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation
    • Johnson LA, Furman CA, Zhang M, Guptaroy B, and Gnegy ME (2005) Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation. Neuropharmacology 49:750-758.
    • (2005) Neuropharmacology , vol.49 , pp. 750-758
    • Johnson, L.A.1    Furman, C.A.2    Zhang, M.3    Guptaroy, B.4    Gnegy, M.E.5
  • 127
    • 0019797154 scopus 로고
    • Proton: Substrate stoichiometries during active transport of biogenic amines in chromaffin ghosts
    • Johnson RG, Carty SE, and Scarpa A (1981) Proton: substrate stoichiometries during active transport of biogenic amines in chromaffin ghosts. J Biol Chem 256: 5773-5780.
    • (1981) J Biol Chem , vol.256 , pp. 5773-5780
    • Johnson, R.G.1    Carty, S.E.2    Scarpa, A.3
  • 132
    • 0031933722 scopus 로고    scopus 로고
    • Protein kinase C inhibitors block amphetaminemediated dopamine release in rat striatal slices
    • Kantor L and Gnegy ME (1998). Protein kinase C inhibitors block amphetaminemediated dopamine release in rat striatal slices. J Pharmacol Exp Ther 284: 592-598.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 592-598
    • Kantor, L.1    Gnegy, M.E.2
  • 133
    • 20344374645 scopus 로고    scopus 로고
    • Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
    • Kessler RC, Chiu WT, Demler O, Merikangas KR, and Walters EE (2005) Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62:617-627.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 617-627
    • Kessler, R.C.1    Chiu, W.T.2    Demler, O.3    Merikangas, K.R.4    Walters, E.E.5
  • 135
    • 0026330894 scopus 로고
    • Cloning and expression of a cocainesensitive rat dopamine transporter
    • Kilty JE, Lorang D, and Amara SG (1991) Cloning and expression of a cocainesensitive rat dopamine transporter. Science 254:578-579.
    • (1991) Science , vol.254 , pp. 578-579
    • Kilty, J.E.1    Lorang, D.2    Amara, S.G.3
  • 136
    • 0019877157 scopus 로고
    • Amine transport in chromaffin granule ghosts. PH dependence implies cationic form is translocated
    • Knoth J, Isaacs JM, and Njus D (1981) Amine transport in chromaffin granule ghosts. pH dependence implies cationic form is translocated. J Biol Chem 256: 6541-6543.
    • (1981) J Biol Chem , vol.256 , pp. 6541-6543
    • Knoth, J.1    Isaacs, J.M.2    Njus, D.3
  • 138
    • 0030965452 scopus 로고    scopus 로고
    • Phosphorylation of a vesicular monoamine transporter by casein kinase II
    • Krantz DE, Peter D, Liu Y, and Edwards RH (1997) Phosphorylation of a vesicular monoamine transporter by casein kinase II. J Biol Chem 272:6752-6759.
    • (1997) J Biol Chem , vol.272 , pp. 6752-6759
    • Krantz, D.E.1    Peter, D.2    Liu, Y.3    Edwards, R.H.4
  • 139
    • 0034640146 scopus 로고    scopus 로고
    • Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: Effects of methylphenidate as measured by single photon emission computed tomography
    • Krause KH, Dresel SH, Krause J, Kung HF, and Tatsch K (2000) Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography. Neurosci Lett 285:107-110.
    • (2000) Neurosci Lett , vol.285 , pp. 107-110
    • Krause, K.H.1    Dresel, S.H.2    Krause, J.3    Kung, H.F.4    Tatsch, K.5
  • 141
    • 84872140737 scopus 로고    scopus 로고
    • Investigating methamphetamine craving using the extinction-reinstatement model in the rat
    • Kufahl PR and Olive MF (2011) Investigating methamphetamine craving using the extinction-reinstatement model in the rat. J Addict Res Ther S1:003.
    • (2011) J Addict Res Ther , vol.S1 , pp. 003
    • Kufahl, P.R.1    Olive, M.F.2
  • 142
  • 143
    • 67651007160 scopus 로고    scopus 로고
    • Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism- dystonia
    • Kurian MA, Zhen J, Cheng SY, Li Y, Mordekar SR, Jardine P, Morgan NV, Meyer E, Tee L, and Pasha S, et al. (2009) Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism- dystonia. J Clin Invest 119:1595-1603.
    • (2009) J Clin Invest , vol.119 , pp. 1595-1603
    • Kurian, M.A.1    Zhen, J.2    Cheng, S.Y.3    Li, Y.4    Mordekar, S.R.5    Jardine, P.6    Morgan, N.V.7    Meyer, E.8    Tee, L.9    Pasha, S.10
  • 144
    • 84905911804 scopus 로고    scopus 로고
    • Neuroprotective roles of pituitary adenylate cyclaseactivating polypeptide in neurodegenerative diseases
    • Lee EH and Seo SR (2014) Neuroprotective roles of pituitary adenylate cyclaseactivating polypeptide in neurodegenerative diseases. BMB Rep 47:369-375.
    • (2014) BMB Rep , vol.47 , pp. 369-375
    • Lee, E.H.1    Seo, S.R.2
  • 145
    • 0035066885 scopus 로고    scopus 로고
    • Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamineinduced apoptosis
    • Lee FJ, Liu F, Pristupa ZB, and Niznik HB (2001) Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamineinduced apoptosis. FASEB J 15:916-926.
    • (2001) FASEB J , vol.15 , pp. 916-926
    • Lee, F.J.1    Liu, F.2    Pristupa, Z.B.3    Niznik, H.B.4
  • 146
    • 34247234971 scopus 로고    scopus 로고
    • Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor
    • Lee FJ, Pei L, Moszczynska A, Vukusic B, Fletcher PJ, and Liu F (2007) Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor. EMBO J 26:2127-2136.
    • (2007) EMBO J , vol.26 , pp. 2127-2136
    • Lee, F.J.1    Pei, L.2    Moszczynska, A.3    Vukusic, B.4    Fletcher, P.J.5    Liu, F.6
  • 148
    • 78651197716 scopus 로고
    • Elucidation of the ratelimiting step in norepinephrine biosynthesis in the perfused guinea-pig heart
    • Levitt M, Spector S, Sjoerdsma A, and Udenfriend S (1965) Elucidation of the ratelimiting step in norepinephrine biosynthesis in the perfused guinea-pig heart. J Pharmacol Exp Ther 148:1-8.
    • (1965) J Pharmacol Exp Ther , vol.148 , pp. 1-8
    • Levitt, M.1    Spector, S.2    Sjoerdsma, A.3    Udenfriend, S.4
  • 149
    • 2442637536 scopus 로고    scopus 로고
    • The role of N-glycosylation in function and surface trafficking of the human dopamine transporter
    • Li LB, Chen N, Ramamoorthy S, Chi L, Cui XN, Wang LC, and Reith ME (2004) The role of N-glycosylation in function and surface trafficking of the human dopamine transporter. J Biol Chem 279:21012-21020.
    • (2004) J Biol Chem , vol.279 , pp. 21012-21020
    • Li, L.B.1    Chen, N.2    Ramamoorthy, S.3    Chi, L.4    Cui, X.N.5    Wang, L.C.6    Reith, M.E.7
  • 150
    • 78751474117 scopus 로고    scopus 로고
    • N-substituted benztropine analogs: Selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects
    • Li SM, Kopajtic TA, O’Callaghan MJ, Agoston GE, Cao J, Newman AH, and Katz JL (2011) N-substituted benztropine analogs: selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects. J Pharmacol Exp Ther 336:575-585.
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 575-585
    • Li, S.M.1    Kopajtic, T.A.2    O’Callaghan, M.J.3    Agoston, G.E.4    Cao, J.5    Newman, A.H.6    Katz, J.L.7
  • 151
    • 0020004473 scopus 로고
    • Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine
    • Liang NY and Rutledge CO (1982) Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine. Biochem Pharmacol 31:983-992.
    • (1982) Biochem Pharmacol , vol.31 , pp. 983-992
    • Liang, N.Y.1    Rutledge, C.O.2
  • 153
    • 0037223687 scopus 로고    scopus 로고
    • Loss of striatal vesicular monoamine transporter protein (VMAT2) in human cocaine users
    • Little KY, Krolewski DM, Zhang L, and Cassin BJ (2003) Loss of striatal vesicular monoamine transporter protein (VMAT2) in human cocaine users. Am J Psychiatry 160:47-55.
    • (2003) Am J Psychiatry , vol.160 , pp. 47-55
    • Little, K.Y.1    Krolewski, D.M.2    Zhang, L.3    Cassin, B.J.4
  • 154
    • 0031044233 scopus 로고    scopus 로고
    • The role of vesicular transport proteins in synaptic transmission and neural degeneration
    • Liu Y and Edwards RH (1997) The role of vesicular transport proteins in synaptic transmission and neural degeneration. Annu Rev Neurosci 20:125-156.
    • (1997) Annu Rev Neurosci , vol.20 , pp. 125-156
    • Liu, Y.1    Edwards, R.H.2
  • 155
    • 0037820586 scopus 로고    scopus 로고
    • The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines
    • Loder MK and Melikian HE (2003) The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines. J Biol Chem 278:22168-22174.
    • (2003) J Biol Chem , vol.278 , pp. 22168-22174
    • Loder, M.K.1    Melikian, H.E.2
  • 158
    • 72249122547 scopus 로고    scopus 로고
    • Randomized controlled trial of dexamphetamine maintenance for the treatment of methamphetamine dependence
    • Longo M, Wickes W, Smout M, Harrison S, Cahill S, and White JM (2010) Randomized controlled trial of dexamphetamine maintenance for the treatment of methamphetamine dependence. Addiction 105:146-154.
    • (2010) Addiction , vol.105 , pp. 146-154
    • Longo, M.1    Wickes, W.2    Smout, M.3    Harrison, S.4    Cahill, S.5    White, J.M.6
  • 159
    • 0036912534 scopus 로고    scopus 로고
    • Biological basis of sex differences in drug abuse: Preclinical and clinical studies
    • Lynch WJ, Roth ME, and Carroll ME (2002) Biological basis of sex differences in drug abuse: preclinical and clinical studies. Psychopharmacology (Berl) 164:121-137.
    • (2002) Psychopharmacology (Berl) , vol.164 , pp. 121-137
    • Lynch, W.J.1    Roth, M.E.2    Carroll, M.E.3
  • 160
    • 84859510210 scopus 로고    scopus 로고
    • Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway
    • Madsen KL, Thorsen TS, Rahbek-Clemmensen T, Eriksen J, and Gether U (2012) Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway. J Biol Chem 287:12293-12308.
    • (2012) J Biol Chem , vol.287 , pp. 12293-12308
    • Madsen, K.L.1    Thorsen, T.S.2    Rahbek-Clemmensen, T.3    Eriksen, J.4    Gether, U.5
  • 161
    • 0025354029 scopus 로고
    • The effects of monoamine uptake inhibitors and methamphetamine on neostriatal 6-hydroxydopamine (6-OHDA) formation, short-term monoamine depletions and locomotor activity in the rat
    • Marek GJ, Vosmer G, and Seiden LS (1990) The effects of monoamine uptake inhibitors and methamphetamine on neostriatal 6-hydroxydopamine (6-OHDA) formation, short-term monoamine depletions and locomotor activity in the rat. Brain Res 516:1-7.
    • (1990) Brain Res , vol.516 , pp. 1-7
    • Marek, G.J.1    Vosmer, G.2    Seiden, L.S.3
  • 163
    • 0034746913 scopus 로고    scopus 로고
    • Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent
    • Mayfield RD and Zahniser NR (2001) Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent. Mol Pharmacol 59:113-121.
    • (2001) Mol Pharmacol , vol.59 , pp. 113-121
    • Mayfield, R.D.1    Zahniser, N.R.2
  • 164
    • 26944484406 scopus 로고    scopus 로고
    • Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder
    • Mazei-Robison MS, Couch RS, Shelton RC, Stein MA, and Blakely RD (2005) Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder. Neuropharmacology 49:724-736.
    • (2005) Neuropharmacology , vol.49 , pp. 724-736
    • Mazei-Robison, M.S.1    Couch, R.S.2    Shelton, R.C.3    Stein, M.A.4    Blakely, R.D.5
  • 165
    • 0032531781 scopus 로고    scopus 로고
    • Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: Evidence from positron emission tomography studies with [11C]WIN-35,428
    • McCann UD, Wong DF, Yokoi F, Villemagne V, Dannals RF, and Ricaurte GA (1998) Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428. J Neurosci 18:8417-8422.
    • (1998) J Neurosci , vol.18 , pp. 8417-8422
    • McCann, U.D.1    Wong, D.F.2    Yokoi, F.3    Villemagne, V.4    Dannals, R.F.5    Ricaurte, G.A.6
  • 167
    • 79953798937 scopus 로고    scopus 로고
    • Eating high-fat chow enhances sensitization to the effects of methamphetamine on locomotion in rats
    • McGuire BA, Baladi MG, and France CP (2011) Eating high-fat chow enhances sensitization to the effects of methamphetamine on locomotion in rats. Eur J Pharmacol 658:156-159.
    • (2011) Eur J Pharmacol , vol.658 , pp. 156-159
    • McGuire, B.A.1    Baladi, M.G.2    France, C.P.3
  • 168
    • 0027337280 scopus 로고
    • D2 receptors may modulate the function of the striatal transporter for dopamine: Kinetic evidence from studies in vitro and in vivo
    • Meiergerd SM, Patterson TA, and Schenk JO (1993) D2 receptors may modulate the function of the striatal transporter for dopamine: kinetic evidence from studies in vitro and in vivo. J Neurochem 61:764-767.
    • (1993) J Neurochem , vol.61 , pp. 764-767
    • Meiergerd, S.M.1    Patterson, T.A.2    Schenk, J.O.3
  • 169
    • 0033568870 scopus 로고    scopus 로고
    • Membrane trafficking regulates the activity of the human dopamine transporter
    • Melikian HE and Buckley KM (1999) Membrane trafficking regulates the activity of the human dopamine transporter. J Neurosci 19:7699-7710.
    • (1999) J Neurosci , vol.19 , pp. 7699-7710
    • Melikian, H.E.1    Buckley, K.M.2
  • 174
    • 0027979190 scopus 로고
    • The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation
    • Milner HE, Béliveau R, and Jarvis SM (1994) The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation. Biochim Biophys Acta 1190:185-187.
    • (1994) Biochim Biophys Acta , vol.1190 , pp. 185-187
    • Milner, H.E.1    Béliveau, R.2    Jarvis, S.M.3
  • 175
    • 33846105336 scopus 로고    scopus 로고
    • Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter
    • Miranda M, Dionne KR, Sorkina T, and Sorkin A (2007) Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter. Mol Biol Cell 18:313-323.
    • (2007) Mol Biol Cell , vol.18 , pp. 313-323
    • Miranda, M.1    Dionne, K.R.2    Sorkina, T.3    Sorkin, A.4
  • 176
    • 27444445600 scopus 로고    scopus 로고
    • Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C
    • Miranda M, Wu CC, Sorkina T, Korstjens DR, and Sorkin A (2005) Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C. J Biol Chem 280:35617-35624.
    • (2005) J Biol Chem , vol.280 , pp. 35617-35624
    • Miranda, M.1    Wu, C.C.2    Sorkina, T.3    Korstjens, D.R.4    Sorkin, A.5
  • 178
    • 35348816727 scopus 로고    scopus 로고
    • Parkin disrupts the alpha-synuclein/dopamine transporter interaction: Consequences toward dopamine-induced toxicity
    • Moszczynska A, Saleh J, Zhang H, Vukusic B, Lee FJ, and Liu F (2007) Parkin disrupts the alpha-synuclein/dopamine transporter interaction: consequences toward dopamine-induced toxicity. J Mol Neurosci 32:217-227.
    • (2007) J Mol Neurosci , vol.32 , pp. 217-227
    • Moszczynska, A.1    Saleh, J.2    Zhang, H.3    Vukusic, B.4    Lee, F.J.5    Liu, F.6
  • 182
    • 33746900423 scopus 로고    scopus 로고
    • The mesolimbic dopamine reward circuit in depression
    • Nestler EJ and Carlezon WA Jr (2006) The mesolimbic dopamine reward circuit in depression. Biol Psychiatry 59:1151-1159.
    • (2006) Biol Psychiatry , vol.59 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon, W.A.2
  • 185
    • 84893179195 scopus 로고    scopus 로고
    • The vesicular monoamine transporter-2: An important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse
    • Nickell JR, Siripurapu KB, Vartak A, Crooks PA, and Dwoskin LP (2014) The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse. Adv Pharmacol 69:71-106.
    • (2014) Adv Pharmacol , vol.69 , pp. 71-106
    • Nickell, J.R.1    Siripurapu, K.B.2    Vartak, A.3    Crooks, P.A.4    Dwoskin, L.P.5
  • 186
    • 0024155484 scopus 로고
    • Effects of cocaine on release and uptake of dopamine in vivo: Differentiation by mathematical modeling
    • Nicolaysen LC and Justice JB Jr (1988) Effects of cocaine on release and uptake of dopamine in vivo: differentiation by mathematical modeling. Pharmacol Biochem Behav 31:327-335.
    • (1988) Pharmacol Biochem Behav , vol.31 , pp. 327-335
    • Nicolaysen, L.C.1    Justice, J.B.2
  • 187
    • 0029898811 scopus 로고    scopus 로고
    • Ultrastructural localization of the vesicular monoamine transporter-2 in midbrain dopaminergic neurons: Potential sites for somatodendritic storage and release of dopamine
    • Nirenberg MJ, Chan J, Liu Y, Edwards RH, and Pickel VM (1996a) Ultrastructural localization of the vesicular monoamine transporter-2 in midbrain dopaminergic neurons: potential sites for somatodendritic storage and release of dopamine. J Neurosci 16:4135-4145.
    • (1996) J Neurosci , vol.16 , pp. 4135-4145
    • Nirenberg, M.J.1    Chan, J.2    Liu, Y.3    Edwards, R.H.4    Pickel, V.M.5
  • 188
    • 0030943452 scopus 로고    scopus 로고
    • Vesicular monoamine transporter-2: Immunogold localization in striatal axons and terminals
    • Nirenberg MJ, Chan J, Liu Y, Edwards RH, and Pickel VM (1997a) Vesicular monoamine transporter-2: immunogold localization in striatal axons and terminals. Synapse 26:194-198.
    • (1997) Synapse , vol.26 , pp. 194-198
    • Nirenberg, M.J.1    Chan, J.2    Liu, Y.3    Edwards, R.H.4    Pickel, V.M.5
  • 189
    • 0030970610 scopus 로고    scopus 로고
    • Immunogold localization of the dopamine transporter: An ultrastructural study of the rat ventral tegmental area
    • Nirenberg MJ, Chan J, Vaughan RA, Uhl GR, Kuhar MJ, and Pickel VM (1997b) Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area. J Neurosci 17:4037-4044.
    • (1997) J Neurosci , vol.17 , pp. 4037-4044
    • Nirenberg, M.J.1    Chan, J.2    Vaughan, R.A.3    Uhl, G.R.4    Kuhar, M.J.5    Pickel, V.M.6
  • 190
    • 0029071155 scopus 로고
    • The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nuclei
    • Nirenberg MJ, Liu Y, Peter D, Edwards RH, and Pickel VM (1995) The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nuclei. Proc Natl Acad Sci USA 92:8773-8777.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8773-8777
    • Nirenberg, M.J.1    Liu, Y.2    Peter, D.3    Edwards, R.H.4    Pickel, V.M.5
  • 191
    • 0030031457 scopus 로고    scopus 로고
    • The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons
    • Nirenberg MJ, Vaughan RA, Uhl GR, Kuhar MJ, and Pickel VM (1996b) The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons. J Neurosci 16:436-447.
    • (1996) J Neurosci , vol.16 , pp. 436-447
    • Nirenberg, M.J.1    Vaughan, R.A.2    Uhl, G.R.3    Kuhar, M.J.4    Pickel, V.M.5
  • 193
    • 84875193461 scopus 로고    scopus 로고
    • The real catecholamine content of secretory vesicles in the CNS revealed by electrochemical cytometry
    • Omiatek DM, Bressler AJ, Cans AS, Andrews AM, Heien ML, and Ewing AG (2013) The real catecholamine content of secretory vesicles in the CNS revealed by electrochemical cytometry. Sci Rep 3:1447.
    • (2013) Sci Rep , vol.3 , pp. 1447
    • Omiatek, D.M.1    Bressler, A.J.2    Cans, A.S.3    Rews, A.M.4    Heien, M.L.5    Ewing, A.G.6
  • 194
    • 77953490405 scopus 로고    scopus 로고
    • Vesicular monoamine and glutamate transporters select distinct synaptic vesicle recycling pathways
    • Onoa B, Li H, Gagnon-Bartsch JA, Elias LA, and Edwards RH (2010) Vesicular monoamine and glutamate transporters select distinct synaptic vesicle recycling pathways. J Neurosci 30:7917-7927.
    • (2010) J Neurosci , vol.30 , pp. 7917-7927
    • Onoa, B.1    Li, H.2    Gagnon-Bartsch, J.A.3    Elias, L.A.4    Edwards, R.H.5
  • 195
    • 24144454799 scopus 로고    scopus 로고
    • Deficits in dopamine clearance and locomotion in hypoinsulinemic rats unmask novel modulation of dopamine transporters by amphetamine
    • Owens WA, Sevak RJ, Galici R, Chang X, Javors MA, Galli A, France CP, and Daws LC (2005) Deficits in dopamine clearance and locomotion in hypoinsulinemic rats unmask novel modulation of dopamine transporters by amphetamine. J Neurochem 94:1402-1410.
    • (2005) J Neurochem , vol.94 , pp. 1402-1410
    • Owens, W.A.1    Sevak, R.J.2    Galici, R.3    Chang, X.4    Javors, M.A.5    Galli, A.6    France, C.P.7    Daws, L.C.8
  • 198
    • 84887404259 scopus 로고    scopus 로고
    • X-ray structure of dopamine transporter elucidates antidepressant mechanism
    • Penmatsa A, Wang KH, and Gouaux E (2013) X-ray structure of dopamine transporter elucidates antidepressant mechanism. Nature 503:85-90.
    • (2013) Nature , vol.503 , pp. 85-90
    • Penmatsa, A.1    Wang, K.H.2    Gouaux, E.3
  • 199
    • 0028263975 scopus 로고
    • The chromaffin granule and synaptic vesicle amine transporters differ in substrate recognition and sensitivity to inhibitors
    • Peter D, Jimenez J, Liu Y, Kim J, and Edwards RH (1994) The chromaffin granule and synaptic vesicle amine transporters differ in substrate recognition and sensitivity to inhibitors. J Biol Chem 269:7231-7237.
    • (1994) J Biol Chem , vol.269 , pp. 7231-7237
    • Peter, D.1    Jimenez, J.2    Liu, Y.3    Kim, J.4    Edwards, R.H.5
  • 200
    • 84902170828 scopus 로고    scopus 로고
    • Is Parkinson’s disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum
    • Pifl C, Rajput A, Reither H, Blesa J, Cavada C, Obeso JA, Rajput AH, and Hornykiewicz O (2014) Is Parkinson’s disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum. J Neurosci 34:8210-8218.
    • (2014) J Neurosci , vol.34 , pp. 8210-8218
    • Pifl, C.1    Rajput, A.2    Reither, H.3    Blesa, J.4    Cavada, C.5    Obeso, J.A.6    Rajput, A.H.7    Hornykiewicz, O.8
  • 201
    • 0017344836 scopus 로고
    • Effect of neuroleptics and other drugs on monoamine uptake by membranes of adrenal chromaffin granules
    • Pletscher A (1977) Effect of neuroleptics and other drugs on monoamine uptake by membranes of adrenal chromaffin granules. Br J Pharmacol 59:419-424.
    • (1977) Br J Pharmacol , vol.59 , pp. 419-424
    • Pletscher, A.1
  • 204
    • 84875126075 scopus 로고    scopus 로고
    • SLC6 transporters: Structure, function, regulation, disease association and therapeutics
    • Pramod AB, Foster J, Carvelli L, and Henry LK (2013) SLC6 transporters: structure, function, regulation, disease association and therapeutics. Mol Aspects Med 34: 197-219.
    • (2013) Mol Aspects Med , vol.34 , pp. 197-219
    • Pramod, A.B.1    Foster, J.2    Carvelli, L.3    Henry, L.K.4
  • 205
    • 78650895843 scopus 로고    scopus 로고
    • Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons
    • Rao A, Simmons D, and Sorkin A (2011) Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons. Mol Cell Neurosci 46:148-158.
    • (2011) Mol Cell Neurosci , vol.46 , pp. 148-158
    • Rao, A.1    Simmons, D.2    Sorkin, A.3
  • 206
    • 0035800785 scopus 로고    scopus 로고
    • The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter
    • Reith ME, Berfield JL, Wang LC, Ferrer JV, and Javitch JA (2001) The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter. J Biol Chem 276:29012-29018.
    • (2001) J Biol Chem , vol.276 , pp. 29012-29018
    • Reith, M.E.1    Berfield, J.L.2    Wang, L.C.3    Ferrer, J.V.4    Javitch, J.A.5
  • 208
    • 0027939074 scopus 로고
    • Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts
    • Reith ME and Coffey LL (1994) Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts. J Pharmacol Exp Ther 271:1444-1452.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 1444-1452
    • Reith, M.E.1    Coffey, L.L.2
  • 210
    • 49449118198 scopus 로고    scopus 로고
    • Dopamine spillover after quantal release: Rethinking dopamine transmission in the nigrostriatal pathway
    • Rice ME and Cragg SJ (2008) Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway. Brain Res Brain Res Rev 58: 303-313.
    • (2008) Brain Res Brain Res Rev , vol.58 , pp. 303-313
    • Rice, M.E.1    Cragg, S.J.2
  • 211
    • 61349110105 scopus 로고    scopus 로고
    • Rapid substrate-induced down-regulation in function and surface localization of dopamine transporters: Rat dorsal striatum versus nucleus accumbens
    • Richards TL and Zahniser NR (2009) Rapid substrate-induced down-regulation in function and surface localization of dopamine transporters: rat dorsal striatum versus nucleus accumbens. J Neurochem 108:1575-1584.
    • (2009) J Neurochem , vol.108 , pp. 1575-1584
    • Richards, T.L.1    Zahniser, N.R.2
  • 212
    • 0037498436 scopus 로고    scopus 로고
    • Neurotensin agonists: Possible drugs for treatment of psychostimulant abuse
    • Richelson E, Boules M, and Fredrickson P (2003) Neurotensin agonists: possible drugs for treatment of psychostimulant abuse. Life Sci 73:679-690.
    • (2003) Life Sci , vol.73 , pp. 679-690
    • Richelson, E.1    Boules, M.2    Fredrickson, P.3
  • 215
    • 33646637279 scopus 로고    scopus 로고
    • Role of monoamine transporters in mediating psychostimulant effects
    • Riddle EL, Fleckenstein AE, and Hanson GR (2005) Role of monoamine transporters in mediating psychostimulant effects. AAPS J 7:E847-E851.
    • (2005) AAPS J , vol.7
    • Riddle, E.L.1    Fleckenstein, A.E.2    Hanson, G.R.3
  • 216
    • 0037008254 scopus 로고    scopus 로고
    • Differential trafficking of the vesicular monoamine transporter-2 by methamphetamine and cocaine
    • Riddle EL, Topham MK, Haycock JW, Hanson GR, and Fleckenstein AE (2002) Differential trafficking of the vesicular monoamine transporter-2 by methamphetamine and cocaine. Eur J Pharmacol 449:71-74.
    • (2002) Eur J Pharmacol , vol.449 , pp. 71-74
    • Riddle, E.L.1    Topham, M.K.2    Haycock, J.W.3    Hanson, G.R.4    Fleckenstein, A.E.5
  • 217
    • 84873520463 scopus 로고    scopus 로고
    • Brain dopamine-serotonin vesicular transport disease and its treatment
    • Rilstone JJ, Alkhater RA, and Minassian BA (2013) Brain dopamine-serotonin vesicular transport disease and its treatment. N Engl J Med 368:543-550.
    • (2013) N Engl J Med , vol.368 , pp. 543-550
    • Rilstone, J.J.1    Alkhater, R.A.2    Minassian, B.A.3
  • 218
    • 0023265754 scopus 로고
    • Cocaine receptors on dopamine transporters are related to self-administration of cocaine
    • Ritz MC, Lamb RJ, Goldberg SR, and Kuhar MJ (1987) Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237: 1219-1223.
    • (1987) Science , vol.237 , pp. 1219-1223
    • Ritz, M.C.1    Lamb, R.J.2    Goldberg, S.R.3    Kuhar, M.J.4
  • 219
    • 84858666230 scopus 로고    scopus 로고
    • Studies of the biogenic amine transporters. 14. Identification of low-efficacy “partial” substrates for the biogenic amine transporters
    • Rothman RB, Partilla JS, Baumann MH, Lightfoot-Siordia C, and Blough BE (2012) Studies of the biogenic amine transporters. 14. Identification of low-efficacy “partial” substrates for the biogenic amine transporters. J Pharmacol Exp Ther 341: 251-262.
    • (2012) J Pharmacol Exp Ther , vol.341 , pp. 251-262
    • Rothman, R.B.1    Partilla, J.S.2    Baumann, M.H.3    Lightfoot-Siordia, C.4    Blough, B.E.5
  • 220
    • 70350619640 scopus 로고    scopus 로고
    • Methylphenidate normalises activation and functional connectivity deficits in attention and motivation networks in medication-naïve children with ADHD during a rewarded continuous performance task
    • Rubia K, Halari R, Cubillo A, Mohammad AM, Brammer M, and Taylor E (2009) Methylphenidate normalises activation and functional connectivity deficits in attention and motivation networks in medication-naïve children with ADHD during a rewarded continuous performance task. Neuropharmacology 57:640-652.
    • (2009) Neuropharmacology , vol.57 , pp. 640-652
    • Rubia, K.1    Halari, R.2    Cubillo, A.3    Mohammad, A.M.4    Brammer, M.5    Taylor, E.6
  • 222
    • 0036812515 scopus 로고    scopus 로고
    • Methylphenidate redistributes vesicular monoamine transporter-2: Role of dopamine receptors
    • Sandoval V, Riddle EL, Hanson GR, and Fleckenstein AE (2002) Methylphenidate redistributes vesicular monoamine transporter-2: role of dopamine receptors. J Neurosci 22:8705-8710.
    • (2002) J Neurosci , vol.22 , pp. 8705-8710
    • Sandoval, V.1    Riddle, E.L.2    Hanson, G.R.3    Fleckenstein, A.E.4
  • 223
    • 0037369811 scopus 로고    scopus 로고
    • Methylphenidate alters vesicular monoamine transport and prevents methamphetamine-induced dopaminergic deficits
    • Sandoval V, Riddle EL, Hanson GR, and Fleckenstein AE (2003) Methylphenidate alters vesicular monoamine transport and prevents methamphetamine-induced dopaminergic deficits. J Pharmacol Exp Ther 304:1181-1187.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 1181-1187
    • Sandoval, V.1    Riddle, E.L.2    Hanson, G.R.3    Fleckenstein, A.E.4
  • 224
    • 0035866091 scopus 로고    scopus 로고
    • Methamphetamine-induced rapid and reversible changes in dopamine transporter function: An in vitro model
    • Sandoval V, Riddle EL, Ugarte YV, Hanson GR, and Fleckenstein AE (2001). Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model. J Neurosci 21:1413-1419.
    • (2001) J Neurosci , vol.21 , pp. 1413-1419
    • Sandoval, V.1    Riddle, E.L.2    Ugarte, Y.V.3    Hanson, G.R.4    Fleckenstein, A.E.5
  • 226
    • 80054728808 scopus 로고    scopus 로고
    • The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors
    • Schmitt KC and Reith ME (2011) The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors. PLoS One 6:e25790.
    • (2011) Plos One , vol.6
    • Schmitt, K.C.1    Reith, M.E.2
  • 227
    • 84879305802 scopus 로고    scopus 로고
    • Nonclassical pharmacology of the dopamine transporter: Atypical inhibitors, allosteric modulators, and partial substrates
    • Schmitt KC, Rothman RB, and Reith ME (2013) Nonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substrates. J Pharmacol Exp Ther 346:2-10.
    • (2013) J Pharmacol Exp Ther , vol.346 , pp. 2-10
    • Schmitt, K.C.1    Rothman, R.B.2    Reith, M.E.3
  • 229
    • 0025284551 scopus 로고
    • Dopamine receptors and transporters in Parkinson’s disease and schizophrenia
    • Seeman P and Niznik HB (1990) Dopamine receptors and transporters in Parkinson’s disease and schizophrenia. FASEB J 4:2737-2744.
    • (1990) FASEB J , vol.4 , pp. 2737-2744
    • Seeman, P.1    Niznik, H.B.2
  • 230
    • 49749112009 scopus 로고    scopus 로고
    • Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats
    • Sevak RJ, Koek W, Owens WA, Galli A, Daws LC, and France CP (2008) Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats. Eur J Pharmacol 592:109-115.
    • (2008) Eur J Pharmacol , vol.592 , pp. 109-115
    • Sevak, R.J.1    Koek, W.2    Owens, W.A.3    Galli, A.4    Daws, L.C.5    France, C.P.6
  • 231
    • 79551598571 scopus 로고    scopus 로고
    • The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter
    • Shan J, Javitch JA, Shi L, and Weinstein H (2011) The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter. PLoS One 6:e16350.
    • (2011) Plos One , vol.6
    • Shan, J.1    Javitch, J.A.2    Shi, L.3    Weinstein, H.4
  • 234
    • 33750039434 scopus 로고
    • The Storage of Norepinephrine and Some of Its Derivatives in Brain Synaptosomes
    • Snyder SH, Glowinski J, and Axelrod J (1965) The Storage of Norepinephrine and Some of Its Derivatives in Brain Synaptosomes. Life Sci 4:797-807.
    • (1965) Life Sci , vol.4 , pp. 797-807
    • Snyder, S.H.1    Glowinski, J.2    Axelrod, J.3
  • 236
    • 0031036030 scopus 로고    scopus 로고
    • Multiple ionic conductances of the human dopamine transporter: The actions of dopamine and psychostimulants
    • Sonders MS, Zhu SJ, Zahniser NR, Kavanaugh MP, and Amara SG (1997) Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants. J Neurosci 17:960-974.
    • (1997) J Neurosci , vol.17 , pp. 960-974
    • Sonders, M.S.1    Zhu, S.J.2    Zahniser, N.R.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 237
    • 0041344534 scopus 로고    scopus 로고
    • Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy
    • Sorkina T, Doolen S, Galperin E, Zahniser NR, and Sorkin A (2003) Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy. J Biol Chem 278:28274-28283.
    • (2003) J Biol Chem , vol.278 , pp. 28274-28283
    • Sorkina, T.1    Doolen, S.2    Galperin, E.3    Zahniser, N.R.4    Sorkin, A.5
  • 238
    • 12744281091 scopus 로고    scopus 로고
    • Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism
    • Sorkina T, Hoover BR, Zahniser NR, and Sorkin A (2005) Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism. Traffic 6:157-170.
    • (2005) Traffic , vol.6 , pp. 157-170
    • Sorkina, T.1    Hoover, B.R.2    Zahniser, N.R.3    Sorkin, A.4
  • 239
    • 33748146552 scopus 로고    scopus 로고
    • RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis
    • Sorkina T, Miranda M, Dionne KR, Hoover BR, Zahniser NR, and Sorkin A (2006) RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis. J Neurosci 26:8195-8205.
    • (2006) J Neurosci , vol.26 , pp. 8195-8205
    • Sorkina, T.1    Miranda, M.2    Dionne, K.R.3    Hoover, B.R.4    Zahniser, N.R.5    Sorkin, A.6
  • 240
    • 84887934289 scopus 로고    scopus 로고
    • Genetics of Parkinson’s disease: The yield
    • Spatola M and Wider C (2014) Genetics of Parkinson’s disease: the yield. Parkinsonism Relat Disord 20 (Suppl 1):S35-S38.
    • (2014) Parkinsonism Relat Disord , vol.20
    • Spatola, M.1    Wider, C.2
  • 241
    • 79951702177 scopus 로고    scopus 로고
    • How addictive drugs disrupt presynaptic dopamine neurotransmission
    • Sulzer D (2011) How addictive drugs disrupt presynaptic dopamine neurotransmission. Neuron 69:628-649.
    • (2011) Neuron , vol.69 , pp. 628-649
    • Sulzer, D.1
  • 242
    • 0027395913 scopus 로고
    • Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons
    • Sulzer D, Maidment NT, and Rayport S (1993) Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons. J Neurochem 60:527-535.
    • (1993) J Neurochem , vol.60 , pp. 527-535
    • Sulzer, D.1    Maidment, N.T.2    Rayport, S.3
  • 243
    • 20644441994 scopus 로고    scopus 로고
    • Mechanisms of neurotransmitter release by amphetamines: A review
    • Sulzer D, Sonders MS, Poulsen NW, and Galli A (2005) Mechanisms of neurotransmitter release by amphetamines: a review. Prog Neurobiol 75:406-433.
    • (2005) Prog Neurobiol , vol.75 , pp. 406-433
    • Sulzer, D.1    Sonders, M.S.2    Poulsen, N.W.3    Galli, A.4
  • 244
    • 0035885487 scopus 로고    scopus 로고
    • Vesicular neurotransmitter transporters in Huntington’s disease: Initial observations and comparison with traditional synaptic markers
    • Suzuki M, Desmond TJ, Albin RL, and Frey KA (2001) Vesicular neurotransmitter transporters in Huntington’s disease: initial observations and comparison with traditional synaptic markers. Synapse 41:329-336.
    • (2001) Synapse , vol.41 , pp. 329-336
    • Suzuki, M.1    Desmond, T.J.2    Albin, R.L.3    Frey, K.A.4
  • 246
    • 0030697880 scopus 로고    scopus 로고
    • Murine vesicular monoamine transporter 2: Molecular cloning and genomic structure
    • Takahashi N and Uhl G (1997) Murine vesicular monoamine transporter 2: molecular cloning and genomic structure. Brain Res Mol Brain Res 49:7-14.
    • (1997) Brain Res Mol Brain Res , vol.49 , pp. 7-14
    • Takahashi, N.1    Uhl, G.2
  • 248
    • 77953163443 scopus 로고    scopus 로고
    • Discovery of drugs to treat cocaine dependence: Behavioral and neurochemical effects of atypical dopamine transport inhibitors
    • Tanda G, Newman AH, and Katz JL (2009b) Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors. Adv Pharmacol 57:253-289.
    • (2009) Adv Pharmacol , vol.57 , pp. 253-289
    • Tanda, G.1    Newman, A.H.2    Katz, J.L.3
  • 249
    • 0034491316 scopus 로고    scopus 로고
    • Efficacy of modafinil compared to dextroamphetamine for the treatment of attention deficit hyperactivity disorder in adults
    • Taylor FB and Russo J (2000) Efficacy of modafinil compared to dextroamphetamine for the treatment of attention deficit hyperactivity disorder in adults. J Child Adolesc Psychopharmacol 10:311-320.
    • (2000) J Child Adolesc Psychopharmacol , vol.10 , pp. 311-320
    • Taylor, F.B.1    Russo, J.2
  • 251
    • 84891757421 scopus 로고    scopus 로고
    • N-terminus regulation of VMAT2 mediates methamphetamine-stimulated efflux
    • Torres B and Ruoho AE (2014) N-terminus regulation of VMAT2 mediates methamphetamine-stimulated efflux. Neuroscience 259:194-202.
    • (2014) Neuroscience , vol.259 , pp. 194-202
    • Torres, B.1    Ruoho, A.E.2
  • 252
    • 0037462827 scopus 로고    scopus 로고
    • Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter
    • Torres GE, Carneiro A, Seamans K, Fiorentini C, Sweeney A, Yao WD, and Caron MG (2003) Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter. J Biol Chem 278:2731-2739.
    • (2003) J Biol Chem , vol.278 , pp. 2731-2739
    • Torres, G.E.1    Carneiro, A.2    Seamans, K.3    Fiorentini, C.4    Sweeney, A.5    Yao, W.D.6    Caron, M.G.7
  • 253
    • 0035026044 scopus 로고    scopus 로고
    • Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1
    • Torres GE, Yao WD, Mohn AR, Quan H, Kim KM, Levey AI, Staudinger J, and Caron MG (2001) Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron 30:121-134.
    • (2001) Neuron , vol.30 , pp. 121-134
    • Torres, G.E.1    Yao, W.D.2    Mohn, A.R.3    Quan, H.4    Kim, K.M.5    Levey, A.I.6    Staudinger, J.7    Caron, M.G.8
  • 254
    • 6944240096 scopus 로고    scopus 로고
    • Dopamine D2 receptor activation increases vesicular dopamine uptake and redistributes vesicular monoamine transporter-2 protein
    • Truong JG, Newman AH, Hanson GR, and Fleckenstein AE (2004) Dopamine D2 receptor activation increases vesicular dopamine uptake and redistributes vesicular monoamine transporter-2 protein. Eur J Pharmacol 504:27-32.
    • (2004) Eur J Pharmacol , vol.504 , pp. 27-32
    • Truong, J.G.1    Newman, A.H.2    Hanson, G.R.3    Fleckenstein, A.E.4
  • 255
    • 0142070767 scopus 로고    scopus 로고
    • Pramipexole increases vesicular dopamine uptake: Implications for treatment of Parkinson’s neurodegeneration
    • Truong JG, Rau KS, Hanson GR, and Fleckenstein AE (2003) Pramipexole increases vesicular dopamine uptake: implications for treatment of Parkinson’s neurodegeneration. Eur J Pharmacol 474:223-226.
    • (2003) Eur J Pharmacol , vol.474 , pp. 223-226
    • Truong, J.G.1    Rau, K.S.2    Hanson, G.R.3    Fleckenstein, A.E.4
  • 256
    • 33646798738 scopus 로고    scopus 로고
    • A review of the use of modafinil for attention-deficit hyperactivity disorder
    • Turner D (2006) A review of the use of modafinil for attention-deficit hyperactivity disorder. Expert Rev Neurother 6:455-468.
    • (2006) Expert Rev Neurother , vol.6 , pp. 455-468
    • Turner, D.1
  • 257
    • 84883766007 scopus 로고    scopus 로고
    • Mechanisms of dopamine transporter regulation in normal and disease states
    • Vaughan RA and Foster JD (2013) Mechanisms of dopamine transporter regulation in normal and disease states. Trends Pharmacol Sci 34:489-496.
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 489-496
    • Vaughan, R.A.1    Foster, J.D.2
  • 258
    • 0030972751 scopus 로고    scopus 로고
    • Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes
    • Vaughan RA, Huff RA, Uhl GR, and Kuhar MJ (1997) Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes. J Biol Chem 272:15541-15546.
    • (1997) J Biol Chem , vol.272 , pp. 15541-15546
    • Vaughan, R.A.1    Huff, R.A.2    Uhl, G.R.3    Kuhar, M.J.4
  • 259
    • 0029816108 scopus 로고    scopus 로고
    • Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis
    • Vaughan RA and Kuhar MJ (1996) Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis. J Biol Chem 271:21672-21680.
    • (1996) J Biol Chem , vol.271 , pp. 21672-21680
    • Vaughan, R.A.1    Kuhar, M.J.2
  • 260
    • 84874371889 scopus 로고    scopus 로고
    • The atypical dopamine transport inhibitor, JHW 007, prevents amphetamine-induced sensitization and synaptic reorganization within the nucleus accumbens
    • Velázquez-Sánchez C, García-Verdugo JM, Murga J, and Canales JJ (2013) The atypical dopamine transport inhibitor, JHW 007, prevents amphetamine-induced sensitization and synaptic reorganization within the nucleus accumbens. Prog Neuropsychopharmacol Biol Psychiatry 44:73-80.
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.44 , pp. 73-80
    • Velázquez-Sánchez, C.1    García-Verdugo, J.M.2    Murga, J.3    Canales, J.J.4
  • 265
    • 35548951840 scopus 로고    scopus 로고
    • Methylphenidate administration alters vesicular monoamine transporter-2 function in cytoplasmic and membrane-associated vesicles
    • Volz TJ, Farnsworth SJ, King JL, Riddle EL, Hanson GR, and Fleckenstein AE (2007) Methylphenidate administration alters vesicular monoamine transporter-2 function in cytoplasmic and membrane-associated vesicles. J Pharmacol Exp Ther 323:738-745.
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 738-745
    • Volz, T.J.1    Farnsworth, S.J.2    King, J.L.3    Riddle, E.L.4    Hanson, G.R.5    Fleckenstein, A.E.6
  • 266
    • 7244227735 scopus 로고    scopus 로고
    • L-arginine increases dopamine transporter activity in rat striatum via a nitric oxide synthase-dependent mechanism
    • Volz TJ and Schenk JO (2004) L-arginine increases dopamine transporter activity in rat striatum via a nitric oxide synthase-dependent mechanism. Synapse 54: 173-182.
    • (2004) Synapse , vol.54 , pp. 173-182
    • Volz, T.J.1    Schenk, J.O.2
  • 268
    • 0035911961 scopus 로고    scopus 로고
    • An acidic motif retains vesicular monoamine transporter 2 on large dense core vesicles
    • Waites CL, Mehta A, Tan PK, Thomas G, Edwards RH, and Krantz DE (2001) An acidic motif retains vesicular monoamine transporter 2 on large dense core vesicles. J Cell Biol 152:1159-1168.
    • (2001) J Cell Biol , vol.152 , pp. 1159-1168
    • Waites, C.L.1    Mehta, A.2    Tan, P.K.3    Thomas, G.4    Edwards, R.H.5    Krantz, D.E.6
  • 270
    • 0032951143 scopus 로고    scopus 로고
    • Membrane-initiated steroid actions and the proteins that mediate them
    • Watson CS and Gametchu B (1999) Membrane-initiated steroid actions and the proteins that mediate them. Proc Soc Exp Biol Med 220:9-19.
    • (1999) Proc Soc Exp Biol Med , vol.220 , pp. 9-19
    • Watson, C.S.1    Gametchu, B.2
  • 271
    • 84907284463 scopus 로고    scopus 로고
    • Pharmacological interventions for adolescents and adults with ADHD: Stimulant and nonstimulant medications and misuse of prescription stimulants
    • Weyandt LL, Oster DR, Marraccini ME, Gudmundsdottir BG, Munro BA, Zavras BM, and Kuhar B (2014) Pharmacological interventions for adolescents and adults with ADHD: stimulant and nonstimulant medications and misuse of prescription stimulants. Psychol Res Behav Manag 7:223-249.
    • (2014) Psychol Res Behav Manag , vol.7 , pp. 223-249
    • Weyandt, L.L.1    Oster, D.R.2    Marraccini, M.E.3    Gudmundsdottir, B.G.4    Munro, B.A.5    Zavras, B.M.6    Kuhar, B.7
  • 272
    • 0027279784 scopus 로고
    • A model of the sodium dependence of dopamine uptake in rat striatal synaptosomes
    • Wheeler DD, Edwards AM, Chapman BM, and Ondo JG (1993) A model of the sodium dependence of dopamine uptake in rat striatal synaptosomes. Neurochem Res 18: 927-936.
    • (1993) Neurochem Res , vol.18 , pp. 927-936
    • Wheeler, D.D.1    Edwards, A.M.2    Chapman, B.M.3    Ondo, J.G.4
  • 273
    • 0029809717 scopus 로고    scopus 로고
    • Substance use among women with eating disorders
    • Wiederman MW and Pryor T (1996) Substance use among women with eating disorders. Int J Eat Disord 20:163-168.
    • (1996) Int J Eat Disord , vol.20 , pp. 163-168
    • Wiederman, M.W.1    Pryor, T.2
  • 274
    • 78650268510 scopus 로고    scopus 로고
    • Advances in the treatment of attention-deficit/hyperactivity disorder: A guide for pediatric neurologists
    • Wigal SB, Chae S, Patel A, and Steinberg-Epstein R (2010) Advances in the treatment of attention-deficit/hyperactivity disorder: a guide for pediatric neurologists. Semin Pediatr Neurol 17:230-236.
    • (2010) Semin Pediatr Neurol , vol.17 , pp. 230-236
    • Wigal, S.B.1    Chae, S.2    Patel, A.3    Steinberg-Epstein, R.4
  • 277
    • 70349147366 scopus 로고    scopus 로고
    • Anti-relapse medications: Preclinical models for drug addiction treatment
    • Yahyavi-Firouz-Abadi N and See RE (2009) Anti-relapse medications: preclinical models for drug addiction treatment. Pharmacol Ther 124:235-247.
    • (2009) Pharmacol Ther , vol.124 , pp. 235-247
    • Yahyavi-Firouz-Abadi, N.1    See, R.E.2
  • 278
    • 33847000909 scopus 로고    scopus 로고
    • The vesicular monoamine transporter 2 contains trafficking signals in both its N-glycosylation and C-terminal domains
    • Yao J and Hersh LB (2007) The vesicular monoamine transporter 2 contains trafficking signals in both its N-glycosylation and C-terminal domains. J Neurochem 100:1387-1396.
    • (2007) J Neurochem , vol.100 , pp. 1387-1396
    • Yao, J.1    Hersh, L.B.2
  • 279
    • 0036316782 scopus 로고    scopus 로고
    • D(3) receptor ligands modulate extracellular dopamine clearance in the nucleus accumbens
    • Zapata A and Shippenberg TS (2002) D(3) receptor ligands modulate extracellular dopamine clearance in the nucleus accumbens. J Neurochem 81:1035-1042.
    • (2002) J Neurochem , vol.81 , pp. 1035-1042
    • Zapata, A.1    Shippenberg, T.S.2
  • 280
    • 84926626345 scopus 로고    scopus 로고
    • Dopamine transporter oligomerization: Impact of combining protomers with differential cocaine analog binding affinities
    • Zhen J, Antonio T, Cheng SY, Ali S, Jones KT, and Reith ME (2015) Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities. J Neurochem 133:167-173.
    • (2015) J Neurochem , vol.133 , pp. 167-173
    • Zhen, J.1    Antonio, T.2    Cheng, S.Y.3    Ali, S.4    Jones, K.T.5    Reith, M.E.6
  • 281
    • 34548684744 scopus 로고    scopus 로고
    • LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake
    • Zhou Z, Zhen J, Karpowich NK, Goetz RM, Law CJ, Reith ME, and Wang DN (2007) LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Science 317:1390-1393.
    • (2007) Science , vol.317 , pp. 1390-1393
    • Zhou, Z.1    Zhen, J.2    Karpowich, N.K.3    Goetz, R.M.4    Law, C.J.5    Reith, M.E.6    Wang, D.N.7
  • 282
    • 0030922926 scopus 로고    scopus 로고
    • Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes
    • Zhu SJ, Kavanaugh MP, Sonders MS, Amara SG, and Zahniser NR (1997) Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes. J Pharmacol Exp Ther 282:1358-1365.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1358-1365
    • Zhu, S.J.1    Kavanaugh, M.P.2    Sonders, M.S.3    Amara, S.G.4    Zahniser, N.R.5
  • 284
    • 0035863172 scopus 로고    scopus 로고
    • Vesicular monoamine transporter concentrations in bipolar disorder type I, schizophrenia, and healthy subjects
    • Zubieta JK, Taylor SF, Huguelet P, Koeppe RA, Kilbourn MR, and Frey KA (2001) Vesicular monoamine transporter concentrations in bipolar disorder type I, schizophrenia, and healthy subjects. Biol Psychiatry 49:110-116.
    • (2001) Biol Psychiatry , vol.49 , pp. 110-116
    • Zubieta, J.K.1    Taylor, S.F.2    Huguelet, P.3    Koeppe, R.A.4    Kilbourn, M.R.5    Frey, K.A.6


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