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Volumn 339, Issue 2, 2011, Pages 662-677

Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 METHOXY 3 (2 PHENYLETHOXY)PHENYL] N,N DIPROPYLETHYLAMINE; 3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; 9 [3 [CIS 3,5 DIMETHYL 4 (3 PHENYLPROPYL) 1 PIPERAZINYL]PROPYL]CARBAZOLE HYDROBROMIDE; [3 [CIS 3,5 DIMETHYL 4 (3 PHENYLPROPYL) 1 PIPERAZINYL]PROPYL]DIPHENYLAMINE HYDROCHLORIDE; AC 927; BD 1063; COCAINE; DOPAMINE TRANSPORTER; N [2 (3,4 DICHLOROPHENYL)ETHYL] 2 DIMETHYLAMINO N METHYLETHYLAMINE; N [2 (3,4 DICHLOROPHENYL)ETHYL] 4 METHYLPIPERAZINE DIHYDROCHLORIDE; N [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (1 PYRROLIDINYL)ETHYLAMINE; N PHENETHYLPIPERIDINE OXALATE; N,N DIPROPYL 2 [4 METHOXY 3 (2 PHENYLETHOXY)PHENYL]ETHYLAMINE MONOHYDROCHLORIDE; NOMIFENSINE; OPIATE ANTAGONIST; RIMCAZOLE; SH 3 24; SH 3 28; SIGMA OPIATE RECEPTOR; SIGMA RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

EID: 80054792966     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.185025     Document Type: Article
Times cited : (54)

References (41)
  • 1
    • 34548662875 scopus 로고    scopus 로고
    • Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching
    • DOI 10.1021/bi700429z
    • Adkins EM, Samuvel DJ, Fog JU, Eriksen J, Jayanthi LD, Vaegter CB, Ramamoorthy S, and Gether U (2007) Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching. Biochemistry 46:10484-10497. (Pubitemid 47417244)
    • (2007) Biochemistry , vol.46 , Issue.37 , pp. 10484-10497
    • Adkins, E.M.1    Samuvel, D.J.2    Fog, J.U.3    Eriksen, J.4    Jayanthi, L.D.5    Vaegter, C.B.6    Ramamoorthy, S.7    Gether, U.8
  • 2
    • 4644357751 scopus 로고    scopus 로고
    • Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self-administration and food maintained responding in rats
    • DOI 10.1016/j.neuropharm.2004.07.007, PII S0028390804002035
    • Barrett AC, Miller JR, Dohrmann JM, and Caine SB (2004) Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self-administration and food maintained responding in rats. Neuropharmacology 47 (Suppl 1):256-273. (Pubitemid 39298269)
    • (2004) Neuropharmacology , vol.47 , Issue.SUPPL. 1 , pp. 256-273
    • Barrett, A.C.1    Miller, J.R.2    Dohrmann, J.M.3    Caine, S.B.4
  • 3
    • 0025826148 scopus 로고
    • Does ≲δλτα∀ receptor antagonism predict clinical antipsychotic efficacy?
    • Borison RL, Diamond BI, and Dren AT (1991) Does ≲δλ τα∀ receptor antagonism predict clinical antipsychotic efficacy? Psychopharmacol Bull 27:103-106.
    • (1991) Psychopharmacol Bull , vol.27 , pp. 103-106
    • Borison, R.L.1    Diamond, B.I.2    Dren, A.T.3
  • 4
    • 0037777740 scopus 로고    scopus 로고
    • 1 receptors: Novel piperazinyl alkyl-bis(4′-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents
    • DOI 10.1021/jm030008u
    • Cao J, Kulkarni SS, Husbands SM, Bowen WD, Williams W, Kopajtic T, Katz JL, George C, and Newman AH (2003) Dual probes for the dopamine transporter and δ1 receptors: novel piperazinyl alkyl-bis(4′-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents. J Med Chem 46:2589-2598. (Pubitemid 36702528)
    • (2003) Journal of Medicinal Chemistry , vol.46 , Issue.13 , pp. 2589-2598
    • Cao, J.1    Kulkarni, S.S.2    Husbands, S.M.3    Bowen, W.D.4    Williams, W.5    Kopajtic, T.6    Katz, J.L.7    George, C.8    Newman, A.H.9
  • 5
    • 0027071673 scopus 로고
    • Ionic zinc may function as an endogenous ligand for the haloperidol-sensitive δ2 receptor in rat brain
    • Connor MA and Chavkin C (1992) Ionic zinc may function as an endogenous ligand for the haloperidol-sensitive δ2 receptor in rat brain. Mol Pharmacol 42:471-479.
    • (1992) Mol Pharmacol , vol.42 , pp. 471-479
    • Connor, M.A.1    Chavkin, C.2
  • 6
    • 0027327824 scopus 로고
    • Synthesis and evaluation of conformationally restricted N-[2-(3,4- dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamines at δ receptors. 2. Piperazines, bicyclic amines, bridged bicyclic amines, and miscellaneous compounds
    • de Costa BR, He XS, Linders JT, Dominguez C, Gu ZQ, Williams W, and Bowen WD (1993) Synthesis and evaluation of conformationally restricted N-[2-(3,4- dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamines at δ receptors. 2. Piperazines, bicyclic amines, bridged bicyclic amines, and miscellaneous compounds. J Med Chem 36:2311-2320.
    • (1993) J Med Chem , vol.36 , pp. 2311-2320
    • De Costa, B.R.1    He, X.S.2    Linders, J.T.3    Dominguez, C.4    Gu, Z.Q.5    Williams, W.6    Bowen, W.D.7
  • 7
    • 0026575012 scopus 로고
    • Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1- pyrrolidinyl)ethylamines: Structural requirements and binding affinity at the δreceptor
    • de Costa BR, Radesca L, Di Paolo L, and Bowen WD (1992) Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1- pyrrolidinyl)ethylamines: structural requirements and binding affinity at the δreceptor. J Med Chem 35:38-47.
    • (1992) J Med Chem , vol.35 , pp. 38-47
    • De Costa, B.R.1    Radesca, L.2    Di Paolo, L.3    Bowen, W.D.4
  • 8
    • 0032482945 scopus 로고    scopus 로고
    • Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter
    • DOI 10.1073/pnas.95.16.9238
    • Ferrer JV and Javitch JA (1998) Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter. Proc Natl Acad Sci USA 95:9238-9243. (Pubitemid 28506215)
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.16 , pp. 9238-9243
    • Ferrer, J.V.1    Javitch, J.A.2
  • 9
    • 43549127315 scopus 로고    scopus 로고
    • Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol
    • DOI 10.1111/j.1471-4159.2008.05262.x
    • Foster JD, Adkins SD, Lever JR, and Vaughan RA (2008) Phorbol ester induced traffickingindependent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol. J Neurochem 105:1683-1699. (Pubitemid 351678491)
    • (2008) Journal of Neurochemistry , vol.105 , Issue.5 , pp. 1683-1699
    • Foster, J.D.1    Adkins, S.D.2    Lever, J.R.3    Vaughan, R.A.4
  • 10
  • 11
    • 77957806150 scopus 로고    scopus 로고
    • Sigma-1 receptors amplify dopamine D1 receptor signaling at presynaptic sites in the prelimbic cortex
    • Fu Y, Zhao Y, Luan W, Dong LY, Dong Y, Lai B, Zhu Y, and Zheng P (2010) Sigma-1 receptors amplify dopamine D1 receptor signaling at presynaptic sites in the prelimbic cortex. Biochim Biophys Acta 1803:1396-1408.
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 1396-1408
    • Fu, Y.1    Zhao, Y.2    Luan, W.3    Dong, L.Y.4    Dong, Y.5    Lai, B.6    Zhu, Y.7    Zheng, P.8
  • 13
    • 2942578089 scopus 로고    scopus 로고
    • Sigma-2 receptors are specifically localized to lipid rafts in rat liver membranes
    • DOI 10.1016/j.ejphar.2004.04.005, PII S0014299904003802
    • Gebreselassie D and Bowen WD (2004) Sigma-2 receptors are specifically localized to lipid rafts in rat liver membranes. Eur J Pharmacol 493:19-28. (Pubitemid 38746928)
    • (2004) European Journal of Pharmacology , vol.493 , Issue.1-3 , pp. 19-28
    • Gebreselassie, D.1    Bowen, W.D.2
  • 14
    • 0028171131 scopus 로고
    • Regulation of [3H]dopamine release from rat striatal slices by sigma receptor ligands
    • Gonzalez-Alvear GM and Werling LL (1994) Regulation of [3H]dopamine release from rat striatal slices by sigma receptor ligands. J Pharmacol Exp Ther 271:212-219.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 212-219
    • Gonzalez-Alvear, G.M.1    Werling, L.L.2
  • 16
    • 0037924355 scopus 로고    scopus 로고
    • 1) binding sites form raft-like microdomains and target lipid droplets on the endoplasmic reticulum: Roles in endoplasmic reticulum lipid compartmentalization and export
    • 1) binding sites) form raft-like microdomains and target lipid droplets on the endoplasmic reticulum: roles in endoplasmic reticulum lipid compartmentalization and export. J Pharmacol Exp Ther 306:718-725.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 718-725
    • Hayashi, T.1    Su, T.P.2
  • 17
    • 23044482434 scopus 로고    scopus 로고
    • The potential role of sigma-1 receptors in lipid transport and lipid raft reconstitution in the brain: Implication for drug abuse
    • DOI 10.1016/j.lfs.2005.05.009, PII S0024320505004856, Yargeted Lipidomics: Endocannabinoids and other Endolipid Modulators
    • Hayashi T and Su TP (2005) The potential role of sigma-1 receptors in lipid transport and lipid raft reconstitution in the brain: implication for drug abuse. Life Sci 77:1612-1624. (Pubitemid 41073656)
    • (2005) Life Sciences , vol.77 , Issue.14 , pp. 1612-1624
    • Hayashi, T.1    Su, T.-P.2
  • 18
    • 65649118524 scopus 로고    scopus 로고
    • Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: Comparisons with monoamine uptake inhibitors
    • Hiranita T, Soto PL, Newman AH, and Katz JL (2009) Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors. J Pharmacol Exp Ther 329:677-686.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 677-686
    • Hiranita, T.1    Soto, P.L.2    Newman, A.H.3    Katz, J.L.4
  • 19
    • 76749142426 scopus 로고    scopus 로고
    • Reinforcing effects of δ-receptor agonists in rats trained to self-administer cocaine
    • Hiranita T, Soto PL, Tanda G, and Katz JL (2010) Reinforcing effects of δ-receptor agonists in rats trained to self-administer cocaine. J Pharmacol Exp Ther 332:515-524.
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 515-524
    • Hiranita, T.1    Soto, P.L.2    Tanda, G.3    Katz, J.L.4
  • 20
    • 77957791961 scopus 로고    scopus 로고
    • Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding
    • Hong WC and Amara SG (2010) Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding. J Biol Chem 285:32616-32626.
    • (2010) J Biol Chem , vol.285 , pp. 32616-32626
    • Hong, W.C.1    Amara, S.G.2
  • 21
    • 0032747157 scopus 로고    scopus 로고
    • Structure-activity relationships at the monoamine transporters and δ receptors for a novel series of 9-[3-(cis-3,5-dimethyl-1- piperazinyl)propyl]carbazole (rimcazole) analogues
    • DOI 10.1021/jm9902943
    • Husbands SM, Izenwasser S, Kopajtic T, Bowen WD, Vilner BJ, Katz JL, and Newman AH (1999) Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3,5-dimethyl-1-piperazinyl) propyl]carbazole (rimcazole) analogues. J Med Chem 42:4446-4455. (Pubitemid 29504148)
    • (1999) Journal of Medicinal Chemistry , vol.42 , Issue.21 , pp. 4446-4455
    • Husbands, S.M.1    Izenwasser, S.2    Kopajtic, T.3    Bowen, W.D.4    Vilner, B.J.5    Katz, J.L.6    Newman, A.H.7
  • 22
    • 0027507496 scopus 로고
    • Cocaine and several δ receptor ligands inhibit dopamine uptake in rat caudata-putamen
    • DOI 10.1016/0014-2999(93)90381-Q
    • Izenwasser S, Newman AH, and Katz JL (1993) Cocaine and several sigma receptor ligands inhibit dopamine uptake in rat caudate-putamen. Eur J Pharmacol 243: 201-205. (Pubitemid 23308523)
    • (1993) European Journal of Pharmacology , vol.243 , Issue.2 , pp. 201-205
    • Izenwasser, S.1    Hauck, N.A.2    Katz, J.L.3
  • 23
    • 0038274157 scopus 로고    scopus 로고
    • Behavioral effects of rimcazole analogues alone and in combination with cocaine
    • DOI 10.1016/S0014-2999(03)01638-8
    • Katz JL, Libby TA, Kopajtic T, Husbands SM, and Newman AH (2003) Behavioral effects of rimcazole analogues alone and in combination with cocaine. Eur J Pharmacol 468:109-119. (Pubitemid 36556254)
    • (2003) European Journal of Pharmacology , vol.468 , Issue.2 , pp. 109-119
    • Katz, J.L.1    Libby, T.A.2    Kopajtic, T.3    Husbands, S.M.4    Newman, A.H.5
  • 26
    • 0037022356 scopus 로고    scopus 로고
    • 2+ switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle
    • 2+ switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle. Proc Natl Acad Sci USA 99:1683-1688.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1683-1688
    • Loland, C.J.1    Norregaard, L.2    Litman, T.3    Gether, U.4
  • 27
    • 34547898058 scopus 로고    scopus 로고
    • 1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward
    • DOI 10.1038/sj.npp.1301323, PII 1301323
    • Martin-Fardon R, Maurice T, Aujla H, Bowen WD, and Weiss F (2007) Differential effects of sigma1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward. Neuropsychopharmacology 32:1967-1973. (Pubitemid 47258516)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.9 , pp. 1967-1973
    • Martin-Fardon, R.1    Maurice, T.2    Aujla, H.3    Bowen, W.D.4    Weiss, F.5
  • 28
    • 70149124100 scopus 로고    scopus 로고
    • Targeting sigma receptors: Novel medication development for drug abuse and addiction
    • Matsumoto RR (2009) Targeting sigma receptors: novel medication development for drug abuse and addiction. Expert Rev Clin Pharmacol 2:351-358.
    • (2009) Expert Rev Clin Pharmacol , vol.2 , pp. 351-358
    • Matsumoto, R.R.1
  • 29
    • 0035843786 scopus 로고    scopus 로고
    • 1 receptors produce anti-cocaine effects in mice
    • DOI 10.1016/S0014-2999(01)00968-2, PII S0014299901009682
    • Matsumoto RR, McCracken KA, Friedman MJ, Pouw B, De Costa BR, and Bowen WD (2001) Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice. Eur J Pharmacol 419:163-174. (Pubitemid 32568215)
    • (2001) European Journal of Pharmacology , vol.419 , Issue.2-3 , pp. 163-174
    • Matsumoto, R.R.1    McCracken, K.A.2    Friedman, M.J.3    Pouw, B.4    De Costa, B.R.5    Bowen, W.D.6
  • 30
    • 70349116879 scopus 로고    scopus 로고
    • The pharmacology of sigma-1 receptors
    • Maurice T and Su TP (2009) The pharmacology of sigma-1 receptors. Pharmacol Ther 124:195-206.
    • (2009) Pharmacol Ther , vol.124 , pp. 195-206
    • Maurice, T.1    Su, T.P.2
  • 34
    • 0035800785 scopus 로고    scopus 로고
    • The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter
    • Reith ME, Berfield JL, Wang LC, Ferrer JV, and Javitch JA (2001) The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter. J Biol Chem 276:29012-29018.
    • (2001) J Biol Chem , vol.276 , pp. 29012-29018
    • Reith, M.E.1    Berfield, J.L.2    Wang, L.C.3    Ferrer, J.V.4    Javitch, J.A.5
  • 35
    • 4544268439 scopus 로고    scopus 로고
    • 1) receptor activation is a key step for the reactivation of cocaine conditioned place preference by drug priming
    • DOI 10.1007/s00213-004-1814-X
    • Romieu P, Meunier J, Garcia D, Zozime N, Martin-Fardon R, Bowen WD, and Maurice T (2004) The sigma 1 (δ1) receptor activation is a key step for the reactivation of cocaine conditioned place preference by drug priming. Psychopharmacology (Berl) 175:154-162. (Pubitemid 39222345)
    • (2004) Psychopharmacology , vol.175 , Issue.2 , pp. 154-162
    • Romieu, P.1    Meunier, J.2    Garcia, D.3    Zozime, N.4    Martin-Pardon, R.5    Bowen, W.D.6    Maurice, T.7
  • 36
    • 0036196967 scopus 로고    scopus 로고
    • 1 receptor in cocaine-induced conditioned place preference: Possible dependence on dopamine uptake blockade
    • DOI 10.1016/S0893-133X(01)00391-8, PII S0893133X01003918
    • Romieu P, Phan VL, Martin-Fardon R, and Maurice T (2002) Involvement of the sigma1 receptor in cocaine-induced conditioned place preference: possible dependence on dopamine uptake blockade. Neuropsychopharmacology 26:444-455. (Pubitemid 34260994)
    • (2002) Neuropsychopharmacology , vol.26 , Issue.4 , pp. 444-455
    • Romieu, P.1    Phan, V.-L.2    Martin-Fardon, R.3    Maurice, T.4
  • 37
    • 0035450480 scopus 로고    scopus 로고
    • Cocaine affects the dynamics of cytoskeletal proteins via sigma1 receptors
    • Su TP and Hayashi T (2001) Cocaine affects the dynamics of cytoskeletal proteins via sigma1 receptors. Trends Pharmacol Sci 22:456-458.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 456-458
    • Su, T.P.1    Hayashi, T.2
  • 38
    • 0141610329 scopus 로고
    • Naloxone-inaccessible a receptor in rat central nervous system
    • Tam SW (1983) Naloxone-inaccessible a receptor in rat central nervous system. Proc Natl Acad Sci USA 80:6703-6707.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 6703-6707
    • Tam, S.W.1
  • 39
    • 0343443375 scopus 로고
    • Sigma (δ) antagonist BMY 14802 prevents methamphetamine-induced sensitization
    • Ujike H, Kanzaki A, Okumura K, Akiyama K, and Otsuki S (1992) Sigma (δ) antagonist BMY 14802 prevents methamphetamine-induced sensitization. Life Sci 50:PL129-PL134.
    • (1992) Life Sci , vol.50
    • Ujike, H.1    Kanzaki, A.2    Okumura, K.3    Akiyama, K.4    Otsuki, S.5
  • 40
    • 0023877507 scopus 로고
    • Electrophysiological effects of BMY 14802, a new potential antipsychotic drug, on midbrain dopamine neurons in the rat: Acute and chronic studies
    • Wachtel SR and White FJ (1988) Electrophysiological effects of BMY 14802, a new potential antipsychotic drug, on midbrain dopamine neurons in the rat: acute and chronic studies. J Pharmacol Exp Ther 244:410-416. (Pubitemid 18042411)
    • (1988) Journal of Pharmacology and Experimental Therapeutics , vol.244 , Issue.1 , pp. 410-416
    • Wachtel, S.R.1    White, F.J.2
  • 41
    • 0027491712 scopus 로고
    • Effects of the selective Sigma receptor ligand, 6-[6-(4- hydroxypiperidinyl)hexyloxy]-3-methylflavone (NPC 16377), on behavioral and toxic effects of cocaine
    • Witkin JM, Terry P, Menkel M, Hickey P, Pontecorvo M, Ferkany J, and Katz JL (1993) Effects of the selective sigma receptor ligand, 6-[6-(4- hydroxypiperidinyl-) hexyloxy]-3-methylflavone (NPC 16377), on behavioral and toxic effects of cocaine. J Pharmacol Exp Ther 266:473-482. (Pubitemid 23318650)
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.266 , Issue.2 , pp. 473-482
    • Witkin, J.M.1    Terry, P.2    Menkel, M.3    Hickey, P.4    Pontecorvo, M.5    Ferkany, J.6    Katz, J.L.7


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