R-modafinil (armodafinil): A unique dopamine uptake inhibitor and potential medication for psychostimulant abuse

Biological Psychiatry

Volumn 72, Issue 5, 2012, Pages 405-413

  Loland, Claus J ^a   Mereu, Maddalena ^b   Okunola, Oluyomi M ^b   Cao, Jianjing ^b   Prisinzano, Thomas E ^c   Mazier, Sonia ^d   Kopajtic, Theresa ^b   Shi, Lei ^d   Katz, Jonathan L ^b   Tanda, Gianluigi ^b   Newman, Amy Hauck ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Abuse liability; addiction; cocaine; dopamine transporter; methamphetamine; microdialysis

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; [2 (TRIMETHYLAMMONIUM)ETHYL]METHANETHIOSULFONATE; ARMODAFINIL; COCAINE; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE TRANSPORTER; JHW 007; MODAFINIL; PSYCHOSTIMULANT AGENT; SODIUM CHLORIDE; THIOMESYLIC ACID METHYL ESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CELL STRAIN COS7; CONTROLLED STUDY; DOPAMINE RECEPTOR BLOCKING; DOPAMINE UPTAKE; DRUG ABUSE; DRUG BINDING; ENANTIOMER; IC 50; MICRODIALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BENZHYDRYL COMPOUNDS; CENTRAL NERVOUS SYSTEM STIMULANTS; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; HUMANS; MALE; MICE; MICRODIALYSIS; NUCLEUS ACCUMBENS; PROTEIN BINDING; SUBSTANCE-RELATED DISORDERS;

EID: 84864622309     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.03.022     Document Type: Article

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