Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent

Molecular Pharmacology

Volumn 59, Issue 1, 2001, Pages 113-121

  Mayfield, R D ^a   Zahniser, N R ^a  

^a The University of Texas at Austin   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; PERTUSSIS TOXIN; SULPIRIDE; (1R (EXO,EXO)) 3 (4 FLUOROPHENYL) 8 METHYL 8 AZABICYCLO(3.2.1)OCTANE 2 CARBOXYLIC ACID, METHYL ESTER; (1R-(EXO,EXO))-3-(4-FLUOROPHENYL)-8-METHYL-8- AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLIC ACID, METHYL ESTER; CARRIER PROTEIN; COCAINE; DOPAMINE UPTAKE INHIBITOR; DRUG DERIVATIVE; MEMBRANE PROTEIN; NERVE PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HYPERPOLARIZATION; MEMBRANE POTENTIAL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; VOLTAGE CLAMP; XENOPUS LAEVIS; ANIMAL; BIOSYNTHESIS; ELECTROPHYSIOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; PHYSIOLOGY; RADIOASSAY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; ELECTROPHYSIOLOGY; GENE EXPRESSION REGULATION; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; OOCYTES; RADIOLIGAND ASSAY; RECEPTORS, DOPAMINE D2; TRANSFECTION; XENOPUS LAEVIS;

EID: 0034746913     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.1.113     Document Type: Article

References (43)

1. Neurotransmitter transporters: Recent progress
2. Acute regulation of norepinephrine transport: I. Protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells
3. A transient calcium-dependent chloride current in the immature Xenopus oocyte
4. Multiple G protein-couple receptors initiate protein kinase C redistribution of GABA transporters in hippocampal neurons
5. Direct in vivo evidence that D2 dopamine receptors can modulate dopamine uptake
6. G protein-mediated mitogen-activated protein kinase activation by two dopamine D2 receptors
7. The dopamine transporter: Immunochemical characterization and localization in brain
8. Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters
9. Dopamine D-2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum
10. Characterization of a recombinant human dopamine transporter in multiple cell lines
11. Activation of D1 and D2 dopamine receptors inhibits protein kinase C activity in striatal synapteneurosomes
12. Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
13. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
14. Alternative splicing directs the expression of two D2 dopamine receptor isoforms
15. Voltage-dependency of the dopamine transporter in the rat substantia nigra
16. Multiple receptors for dopamine
17. Prominence of the dopamine D2 short isoform in dopaminergic pathways
18. Alterations in dopamine release but not dopamine autoreceptor function in dopamine D3 receptor mutant mice
19. Localization of dopamine transporter protein by microscopic histochemistry
20. Neurotransmitter receptors and ionic conductances regulating the activity of neurones in substantia nigra pars compacta and ventral tegmental area
21. Lack of autoreceptor-mediated inhibitory control of dopamine release in striatal synaptosomes of D2 receptor-deficient mice
22. D2 receptors may modulate the function of the striatal transporter for dopamine: Kinetic evidence from studies in vitro and in vivo
23. Membrane trafficking regulates the activity of the human dopamine transporter
24. Loss of autoreceptor function in dopaminergic neurons from dopamine D2 receptor deficient mice
25. Multiple D2 dopamine receptors produced by alternative RNA splicing
26. Cloning and characterization of Kir3.1 (GIRK1) C-terminal alternative splice variants
27. Co-administration of the D2 antagonist pimozide inhibits up-regulation of dopamine release and uptake induced by repeated cocaine
28. Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter
29. Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1
30. 3H]tropane to the dopamine uptake carrier
31. Regionally specific effects of haloperidol and clozapine on dopamine reuptake in the striatum
32. Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter
33. Novel dopamine receptors half a decade later
34. Multiple ionic conductances of the human dopamine transporter: The actions of dopamine and psychostimulants
35. Modulation of neurotransmitter release by presynaptic autoreceptors
36. Inhibition of dopamine synthesis in striatal synaptosomes by lisuride: Stereospecific reversal by (-)-sulpiride
37. Transporter explosion: Update on uptake
38. D1 dopamine receptor stimulation enables the postsynaptic, but not autoreceptor, effects of D2 dopamine agonists in nigrostriatal and mesoaccumbens dopamine systems
39. Selective activation of Galphao by D2L dopamine receptors in NS20Y neuroblastema cells
40. D2, D3, and D4 dopamine receptors couple to G protein-regulated potassium channels in Xenopus oocytes
41. Synaptic regulation of mesocerticolimbic dopamine neurons
42. Regulation of the functional activity of the human dopamine transporter by protein kinase C
43. Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes