-
1
-
-
0030071106
-
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
-
Giros, B., Jaber, M., Jones, S. R., Wightman, R. M., and Caron, M. G. (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379, 606-612
-
(1996)
Nature
, vol.379
, pp. 606-612
-
-
Giros, B.1
Jaber, M.2
Jones, S.R.3
Wightman, R.M.4
Caron, M.G.5
-
2
-
-
33646840631
-
The dopamine transporter proteome
-
Torres, G. E. (2006) The dopamine transporter proteome. J. Neurochem. 97, Suppl. 1, 3-10
-
(2006)
J. Neurochem.
, vol.97
, Issue.SUPPL. 1
, pp. 3-10
-
-
Torres, G.E.1
-
3
-
-
33751286595
-
Role of ERK in cocaine addiction
-
Lu, L., Koya, E., Zhai, H., Hope, B. T., and Shaham, Y. (2006) Role of ERK in cocaine addiction. Trends Neurosci. 29, 695-703
-
(2006)
Trends Neurosci.
, vol.29
, pp. 695-703
-
-
Lu, L.1
Koya, E.2
Zhai, H.3
Hope, B.T.4
Shaham, Y.5
-
4
-
-
0033215266
-
Dopamine transporters and neuronal injury
-
Miller, G. W., Gainetdinov, R. R., Levey, A. I., and Caron, M. G. (1999) Dopamine transporters and neuronal injury. Trends Pharmacol. Sci. 20, 424-429
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 424-429
-
-
Miller, G.W.1
Gainetdinov, R.R.2
Levey, A.I.3
Caron, M.G.4
-
5
-
-
0002777508
-
-
(Borroni, E., and Kupfer, D. J., eds) Raven Press Ltd., New York
-
Bannon, M. J., Sacchetti, P., and Granneman, J. G. (1995) in Psychopharmacology: the fourth generation of progress (Borroni, E., and Kupfer, D. J., eds) pp. 179-188, Raven Press Ltd., New York
-
(1995)
Psychopharmacology: The Fourth Generation of Progress
, pp. 179-188
-
-
Bannon, M.J.1
Sacchetti, P.2
Granneman, J.G.3
-
6
-
-
62149131065
-
A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward facing conformation
-
Guptaroy, B., Zhang, M., Bowton, E., Binda, F., Shi, L., Weinstein, H., Galli, A., Javitch, J. A., Neubig, R. R., and Gnegy, M. (2009) A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward facing conformation. Mol. Pharmacol. 75, 514-524
-
(2009)
Mol. Pharmacol.
, vol.75
, pp. 514-524
-
-
Guptaroy, B.1
Zhang, M.2
Bowton, E.3
Binda, F.4
Shi, L.5
Weinstein, H.6
Galli, A.7
Javitch, J.A.8
Neubig, R.R.9
Gnegy, M.10
-
7
-
-
77949281313
-
Regulation of the dopamine transporter. Aspects relevant to psychostimulant drugs of abuse
-
Schmitt, K. C., and Reith, M. E. (2010) Regulation of the dopamine transporter. Aspects relevant to psychostimulant drugs of abuse. Ann. N.Y. Acad. Sci. 1187, 316-340
-
(2010)
Ann. N.Y. Acad. Sci.
, vol.1187
, pp. 316-340
-
-
Schmitt, K.C.1
Reith, M.E.2
-
8
-
-
79960673062
-
SLC6 neurotransmitter transporters. Structure, function, and regulation
-
Kristensen, A. S., Andersen, J., Jørgensen, T. N., Sørensen, L., Eriksen, J., Loland, C. J., Strømgaard, K., and Gether, U. (2011) SLC6 neurotransmitter transporters. Structure, function, and regulation. Pharmacol. Rev. 63, 585-640
-
(2011)
Pharmacol. Rev.
, vol.63
, pp. 585-640
-
-
Kristensen, A.S.1
Andersen, J.2
Jørgensen, T.N.3
Sørensen, L.4
Eriksen, J.5
Loland, C.J.6
Strømgaard, K.7
Gether, U.8
-
9
-
-
78651366871
-
The ugly side of amphetamines. Short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"), methamphetamine, and D-amphetamine
-
Steinkellner, T., Freissmuth, M., Sitte, H. H., and Montgomery, T. (2011) The ugly side of amphetamines. Short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"), methamphetamine, and D-amphetamine. Biol. Chem. 392, 103-115
-
(2011)
Biol. Chem.
, vol.392
, pp. 103-115
-
-
Steinkellner, T.1
Freissmuth, M.2
Sitte, H.H.3
Montgomery, T.4
-
10
-
-
72849113289
-
The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters. Why amphetamines take two to tango
-
Sitte, H. H., and Freissmuth, M. (2010) The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters. Why amphetamines take two to tango. J. Neurochem. 112, 340-355
-
(2010)
J. Neurochem.
, vol.112
, pp. 340-355
-
-
Sitte, H.H.1
Freissmuth, M.2
-
11
-
-
20644441994
-
Mechanisms of neurotransmitter release by amphetamines. A review
-
Sulzer, D., Sonders, M. S., Poulsen, N. W., and Galli, A. (2005) Mechanisms of neurotransmitter release by amphetamines. A review. Prog. Neurobiol. 75, 406-433
-
(2005)
Prog. Neurobiol.
, vol.75
, pp. 406-433
-
-
Sulzer, D.1
Sonders, M.S.2
Poulsen, N.W.3
Galli, A.4
-
12
-
-
0031036030
-
Multiple ionic conductances of the human dopamine transporter. The actions of dopamine and psychostimulants
-
Sonders, M. S., Zhu, S. J., Zahniser, N. R., Kavanaugh, M. P., and Amara, S. G. (1997) Multiple ionic conductances of the human dopamine transporter. The actions of dopamine and psychostimulants. J. Neurosci. 17, 960-974
-
(1997)
J. Neurosci.
, vol.17
, pp. 960-974
-
-
Sonders, M.S.1
Zhu, S.J.2
Zahniser, N.R.3
Kavanaugh, M.P.4
Amara, S.G.5
-
13
-
-
0031846705
-
Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter
-
Sitte, H. H., Huck, S., Reither, H., Boehm, S., Singer, E. A., and Pifl, C. (1998) Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter. J. Neurochem. 71, 1289-1297
-
(1998)
J. Neurochem.
, vol.71
, pp. 1289-1297
-
-
Sitte, H.H.1
Huck, S.2
Reither, H.3
Boehm, S.4
Singer, E.A.5
Pifl, C.6
-
14
-
-
66149087730
-
A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters
-
Robertson, S. D., Matthies, H. J., and Galli, A. (2009) A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters. Mol. Neurobiol. 39, 73-80
-
(2009)
Mol. Neurobiol.
, vol.39
, pp. 73-80
-
-
Robertson, S.D.1
Matthies, H.J.2
Galli, A.3
-
15
-
-
0035673504
-
--dependent neurotransmitter transporters. Drugs, substrates, presynaptic receptors, and signaling systems
-
--dependent neurotransmitter transporters. Drugs, substrates, presynaptic receptors, and signaling systems. Pharmacol. Ther. 92, 21-55
-
(2001)
Pharmacol. Ther.
, vol.92
, pp. 21-55
-
-
Zahniser, N.R.1
Doolen, S.2
-
16
-
-
79151476913
-
Regulation of monoamine transporters. Role of transporter phosphorylation
-
Ramamoorthy, S., Shippenberg, T. S., and Jayanthi, L. D. (2011) Regulation of monoamine transporters. Role of transporter phosphorylation. Pharmacol. Ther. 129, 220-238
-
(2011)
Pharmacol. Ther.
, vol.129
, pp. 220-238
-
-
Ramamoorthy, S.1
Shippenberg, T.S.2
Jayanthi, L.D.3
-
17
-
-
0030972751
-
Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes
-
Vaughan, R. A., Huff, R. A., Uhl, G. R., and Kuhar, M. J. (1997) Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes. J. Biol. Chem. 272, 15541-15546
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15541-15546
-
-
Vaughan, R.A.1
Huff, R.A.2
Uhl, G.R.3
Kuhar, M.J.4
-
18
-
-
22344431879
-
Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell surface redistribution
-
Garcia, B. G., Wei, Y., Moron, J. A., Lin, R. Z., Javitch, J. A., and Galli, A. (2005) Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell surface redistribution. Mol. Pharmacol. 68, 102-109
-
(2005)
Mol. Pharmacol.
, vol.68
, pp. 102-109
-
-
Garcia, B.G.1
Wei, Y.2
Moron, J.A.3
Lin, R.Z.4
Javitch, J.A.5
Galli, A.6
-
19
-
-
33747141753
-
Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport
-
Fog, J. U., Khoshbouei, H., Holy, M., Owens, W. A., Vaegter, C. B., Sen, N., Nikandrova, Y., Bowton, E., McMahon, D. G., Colbran, R. J., Daws, L. C., Sitte, H. H., Javitch, J. A., Galli, A., and Gether, U. (2006) Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport. Neuron 51, 417-429
-
(2006)
Neuron
, vol.51
, pp. 417-429
-
-
Fog, J.U.1
Khoshbouei, H.2
Holy, M.3
Owens, W.A.4
Vaegter, C.B.5
Sen, N.6
Nikandrova, Y.7
Bowton, E.8
McMahon, D.G.9
Colbran, R.J.10
Daws, L.C.11
Sitte, H.H.12
Javitch, J.A.13
Galli, A.14
Gether, U.15
-
20
-
-
0141569571
-
Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity
-
Morón, J. A., Zakharova, I., Ferrer, J. V., Merrill, G. A., Hope, B., Lafer, E. M., Lin, Z. C., Wang, J. B., Javitch, J. A., Galli, A., and Shippenberg, T. S. (2003) Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity. J. Neurosci. 23, 8480-8488
-
(2003)
J. Neurosci.
, vol.23
, pp. 8480-8488
-
-
Morón, J.A.1
Zakharova, I.2
Ferrer, J.V.3
Merrill, G.A.4
Hope, B.5
Lafer, E.M.6
Lin, Z.C.7
Wang, J.B.8
Javitch, J.A.9
Galli, A.10
Shippenberg, T.S.11
-
21
-
-
0037067690
-
Dopamine transporters are phosphorylated on N-terminal serines in rat striatum
-
Foster, J. D., Pananusorn, B., and Vaughan, R. A. (2002) Dopamine transporters are phosphorylated on N-terminal serines in rat striatum. J. Biol. Chem. 277, 25178-25186
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25178-25186
-
-
Foster, J.D.1
Pananusorn, B.2
Vaughan, R.A.3
-
22
-
-
28844445514
-
Psychoactive substrates stimulate dopamine transporter phosphorylation and downregulation by cocaine-sensitive and protein kinase C-dependent mechanisms
-
Cervinski, M. A., Foster, J. D., and Vaughan, R. A. (2005) Psychoactive substrates stimulate dopamine transporter phosphorylation and downregulation by cocaine-sensitive and protein kinase C-dependent mechanisms. J. Biol. Chem. 280, 40442-40449
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40442-40449
-
-
Cervinski, M.A.1
Foster, J.D.2
Vaughan, R.A.3
-
23
-
-
0037775994
-
N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization
-
Granas, C., Ferrer, J., Loland, C. J., Javitch, J. A., and Gether, U. (2003) N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization. J. Biol. Chem. 278, 4990-5000
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4990-5000
-
-
Granas, C.1
Ferrer, J.2
Loland, C.J.3
Javitch, J.A.4
Gether, U.5
-
24
-
-
0036535975
-
Pinning down proline-directed phosphorylation signaling
-
Lu, K. P., Liou, Y. C., and Zhou, X. Z. (2002) Pinning down proline-directed phosphorylation signaling. Trends Cell Biol. 12, 164-172
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 164-172
-
-
Lu, K.P.1
Liou, Y.C.2
Zhou, X.Z.3
-
25
-
-
35448945269
-
The prolyl isomerase PIN1. A pivotal new twist in phosphorylation signaling and disease
-
Lu, K. P., and Zhou, X. Z. (2007) The prolyl isomerase PIN1. A pivotal new twist in phosphorylation signaling and disease. Nat. Rev. Mol. Cell Biol. 8, 904-916
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 904-916
-
-
Lu, K.P.1
Zhou, X.Z.2
-
26
-
-
0030850429
-
Role of the pyrrolidine ring of proline in determining the substrate specificity of cdc2 kinase or cdk5
-
Ando, S., Ikuhara, T., Kamata, T., Sasaki, Y., Hisanaga, S., Kishimoto, T., Ito, H., and Inagaki, M. (1997) Role of the pyrrolidine ring of proline in determining the substrate specificity of cdc2 kinase or cdk5. J. Biochem. 122, 409-414
-
(1997)
J. Biochem.
, vol.122
, pp. 409-414
-
-
Ando, S.1
Ikuhara, T.2
Kamata, T.3
Sasaki, Y.4
Hisanaga, S.5
Kishimoto, T.6
Ito, H.7
Inagaki, M.8
-
27
-
-
3042822555
-
Getting in the ring. Proline-directed substrate specificity in the cell cycle proteins Cdc14 and CDK2-cyclinA3
-
Gray, C. H., and Barford, D. (2003) Getting in the ring. Proline-directed substrate specificity in the cell cycle proteins Cdc14 and CDK2-cyclinA3. Cell Cycle 2, 500-502
-
(2003)
Cell Cycle
, vol.2
, pp. 500-502
-
-
Gray, C.H.1
Barford, D.2
-
28
-
-
0033224309
-
The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
-
Brown, N. R., Noble, M. E., Endicott, J. A., and Johnson, L. N. (1999) The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Nat. Cell Biol. 1, 438-443
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 438-443
-
-
Brown, N.R.1
Noble, M.E.2
Endicott, J.A.3
Johnson, L.N.4
-
29
-
-
61449170264
-
Proline-directed phosphorylation of the dopamine transporter N-terminal domain
-
Gorentla, B. K., Moritz, A. E., Foster, J. D., and Vaughan, R. A. (2009) Proline-directed phosphorylation of the dopamine transporter N-terminal domain. Biochemistry 48, 1067-1076
-
(2009)
Biochemistry
, vol.48
, pp. 1067-1076
-
-
Gorentla, B.K.1
Moritz, A.E.2
Foster, J.D.3
Vaughan, R.A.4
-
30
-
-
0027488652
-
125I]RTI-82)
-
125I]RTI-82). J. Labelled Compd. Radiopharm. 33, 1131-1137
-
(1993)
J. Labelled Compd. Radiopharm.
, vol.33
, pp. 1131-1137
-
-
Lever, J.R.1
Carroll, F.I.2
Patel, A.3
Abraham, P.4
Boja, J.W.5
Lewin, A.H.6
Lew, R.7
-
31
-
-
0028229855
-
Stable expression of biogenic amine transporters reveals differences in inhibitor sensitivity, kinetics, and ion dependence
-
Gu, H., Wall, S. C., and Rudnick, G. (1994) Stable expression of biogenic amine transporters reveals differences in inhibitor sensitivity, kinetics, and ion dependence. J. Biol. Chem. 269, 7124-7130
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7124-7130
-
-
Gu, H.1
Wall, S.C.2
Rudnick, G.3
-
32
-
-
38049132028
-
Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression
-
Yang, J. W., Vacher, H., Park, K. S., Clark, E., and Trimmer, J. S. (2007) Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression. Proc. Natl. Acad. Sci. U.S.A. 104, 20055-20060
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 20055-20060
-
-
Yang, J.W.1
Vacher, H.2
Park, K.S.3
Clark, E.4
Trimmer, J.S.5
-
33
-
-
70349977109
-
Hippocampal protein levels related to spatial memory are different in the Barnes maze and in the multiple T-maze
-
Zheng, J. F., Patil, S. S., Chen, W. Q., An, W., He, J. Q., Höger, H., and Lubec, G. (2009) Hippocampal protein levels related to spatial memory are different in the Barnes maze and in the multiple T-maze. J. Proteome Res. 8, 4479-4486
-
(2009)
J. Proteome Res.
, vol.8
, pp. 4479-4486
-
-
Zheng, J.F.1
Patil, S.S.2
Chen, W.Q.3
An, W.4
He, J.Q.5
Höger, H.6
Lubec, G.7
-
34
-
-
1342265784
-
Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter
-
Gaffaney, J. D., and Vaughan, R. A. (2004) Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Mol. Pharmacol. 65, 692-701
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 692-701
-
-
Gaffaney, J.D.1
Vaughan, R.A.2
-
35
-
-
79953132315
-
Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation
-
Foster, J. D., and Vaughan, R. A. (2011) Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. J. Biol. Chem. 286, 5175-5186
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 5175-5186
-
-
Foster, J.D.1
Vaughan, R.A.2
-
36
-
-
34247884590
-
125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter
-
125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter. J. Biol. Chem. 282, 8915-8925
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 8915-8925
-
-
Vaughan, R.A.1
Sakrikar, D.S.2
Parnas, M.L.3
Adkins, S.4
Foster, J.D.5
Duval, R.A.6
Lever, J.R.7
Kulkarni, S.S.8
Hauck-Newman, A.9
-
37
-
-
0029816108
-
Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis
-
Vaughan, R. A., and Kuhar, M. J. (1996) Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis. J. Biol. Chem. 271, 21672-21680
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21672-21680
-
-
Vaughan, R.A.1
Kuhar, M.J.2
-
38
-
-
43549127315
-
Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol
-
Foster, J. D., Adkins, S. D., Lever, J. R., and Vaughan, R. A. (2008) Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol. J. Neurochem. 105, 1683-1699
-
(2008)
J. Neurochem.
, vol.105
, pp. 1683-1699
-
-
Foster, J.D.1
Adkins, S.D.2
Lever, J.R.3
Vaughan, R.A.4
-
39
-
-
0034117176
-
Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression
-
Lin, Z., Itokawa, M., and Uhl, G. R. (2000) Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. FASEB J. 14, 715-728
-
(2000)
FASEB J.
, vol.14
, pp. 715-728
-
-
Lin, Z.1
Itokawa, M.2
Uhl, G.R.3
-
40
-
-
80052245062
-
A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport
-
Henry, L. K., Iwamoto, H., Field, J. R., Kaufmann, K., Dawson, E. S., Jacobs, M. T., Adams, C., Felts, B., Zdravkovic, I., Armstrong, V., Combs, S., Solis, E., Rudnick, G., Noskov, S. Y., DeFelice, L. J., Meiler, J., and Blakely, R. D. (2011) A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport. J. Biol. Chem. 286, 30823-30836
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30823-30836
-
-
Henry, L.K.1
Iwamoto, H.2
Field, J.R.3
Kaufmann, K.4
Dawson, E.S.5
Jacobs, M.T.6
Adams, C.7
Felts, B.8
Zdravkovic, I.9
Armstrong, V.10
Combs, S.11
Solis, E.12
Rudnick, G.13
Noskov, S.Y.14
DeFelice, L.J.15
Meiler, J.16
Blakely, R.D.17
-
41
-
-
0037077196
-
The role of zinc ions in reverse transport mediated by monoamine transporters
-
Scholze, P., Nørregaard, L., Singer, E. A., Freissmuth, M., Gether, U., and Sitte, H. H. (2002) The role of zinc ions in reverse transport mediated by monoamine transporters. J. Biol. Chem. 277, 21505-21513
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21505-21513
-
-
Scholze, P.1
Nørregaard, L.2
Singer, E.A.3
Freissmuth, M.4
Gether, U.5
Sitte, H.H.6
-
42
-
-
0035979829
-
Substantial loss of substrate by diffusion during uptake in HEK-293 cells expressing neurotransmitter transporters
-
Scholze, P., Sitte, H. H., and Singer, E. A. (2001) Substantial loss of substrate by diffusion during uptake in HEK-293 cells expressing neurotransmitter transporters. Neurosci. Lett. 309, 173-176
-
(2001)
Neurosci. Lett.
, vol.309
, pp. 173-176
-
-
Scholze, P.1
Sitte, H.H.2
Singer, E.A.3
-
43
-
-
0032784319
-
Molecular cloning of the mouse dopamine transporter and pharmacological comparison with the human homologue
-
Wu, X., and Gu, H. H. (1999) Molecular cloning of the mouse dopamine transporter and pharmacological comparison with the human homologue. Gene 233, 163-170
-
(1999)
Gene
, vol.233
, pp. 163-170
-
-
Wu, X.1
Gu, H.H.2
-
44
-
-
0026335164
-
Cloning and functional characterization of a cocaine-sensitive dopamine transporter
-
Giros, B., el Mestikawy, S., Bertrand, L., and Caron, M. G. (1991) Cloning and functional characterization of a cocaine-sensitive dopamine transporter. FEBS Lett. 295, 149-154
-
(1991)
FEBS Lett.
, vol.295
, pp. 149-154
-
-
Giros, B.1
El Mestikawy, S.2
Bertrand, L.3
Caron, M.G.4
-
45
-
-
3042648050
-
Phosphorylation and regulation of psychostimulant-sensitive neurotransmitter transporters
-
Vaughan, R. A. (2004) Phosphorylation and regulation of psychostimulant-sensitive neurotransmitter transporters. J. Pharmacol. Exp. Ther. 310, 1-7
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 1-7
-
-
Vaughan, R.A.1
-
46
-
-
0037474101
-
Dopamine transporters are dephosphorylated in striatal homogenates and in vitro by protein phosphatase 1
-
Foster, J. D., Pananusorn, B., Cervinski, M. A., Holden, H. E., and Vaughan, R. A. (2003) Dopamine transporters are dephosphorylated in striatal homogenates and in vitro by protein phosphatase 1. Brain Res. Mol. Brain Res. 110, 100-108
-
(2003)
Brain Res. Mol. Brain Res.
, vol.110
, pp. 100-108
-
-
Foster, J.D.1
Pananusorn, B.2
Cervinski, M.A.3
Holden, H.E.4
Vaughan, R.A.5
-
47
-
-
34248182543
-
Regulation of the dopamine transporter by phosphorylation
-
Foster, J. D., Cervinski, M. A., Gorentla, B. K., and Vaughan, R. A. (2006) Regulation of the dopamine transporter by phosphorylation. Handb. Exp. Pharmacol., 197-214
-
(2006)
Handb. Exp. Pharmacol.
, pp. 197-214
-
-
Foster, J.D.1
Cervinski, M.A.2
Gorentla, B.K.3
Vaughan, R.A.4
-
48
-
-
2442637536
-
The role of N-glycosylation in function and surface trafficking of the human dopamine transporter
-
Li, L. B., Chen, N., Ramamoorthy, S., Chi, L., Cui, X. N., Wang, L. C., and Reith, M. E. (2004) The role of N-glycosylation in function and surface trafficking of the human dopamine transporter. J. Biol. Chem. 279, 21012-21020
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21012-21020
-
-
Li, L.B.1
Chen, N.2
Ramamoorthy, S.3
Chi, L.4
Cui, X.N.5
Wang, L.C.6
Reith, M.E.7
-
49
-
-
0036316735
-
PI 3-kinase regulation of dopamine uptake
-
Carvelli, L., Morón, J. A., Kahlig, K. M., Ferrer, J. V., Sen, N., Lechleiter, J. D., Leeb-Lundberg, L. M., Merrill, G., Lafer, E. M., Ballou, L. M., Shippenberg, T. S., Javitch, J. A., Lin, R. Z., and Galli, A. (2002) PI 3-kinase regulation of dopamine uptake. J. Neurochem. 81, 859-869
-
(2002)
J. Neurochem.
, vol.81
, pp. 859-869
-
-
Carvelli, L.1
Morón, J.A.2
Kahlig, K.M.3
Ferrer, J.V.4
Sen, N.5
Lechleiter, J.D.6
Leeb-Lundberg, L.M.7
Merrill, G.8
Lafer, E.M.9
Ballou, L.M.10
Shippenberg, T.S.11
Javitch, J.A.12
Lin, R.Z.13
Galli, A.14
-
50
-
-
37249049733
-
Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors
-
Zapata, A., Kivell, B., Han, Y., Javitch, J. A., Bolan, E. A., Kuraguntla, D., Jaligam, V., Oz, M., Jayanthi, L. D., Samuvel, D. J., Ramamoorthy, S., and Shippenberg, T. S. (2007) Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors. J. Biol. Chem. 282, 35842-35854
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35842-35854
-
-
Zapata, A.1
Kivell, B.2
Han, Y.3
Javitch, J.A.4
Bolan, E.A.5
Kuraguntla, D.6
Jaligam, V.7
Oz, M.8
Jayanthi, L.D.9
Samuvel, D.J.10
Ramamoorthy, S.11
Shippenberg, T.S.12
-
51
-
-
34247234971
-
Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor
-
Lee, F. J., Pei, L., Moszczynska, A., Vukusic, B., Fletcher, P. J., and Liu, F. (2007) Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor. EMBO J. 26, 2127-2136
-
(2007)
EMBO J.
, vol.26
, pp. 2127-2136
-
-
Lee, F.J.1
Pei, L.2
Moszczynska, A.3
Vukusic, B.4
Fletcher, P.J.5
Liu, F.6
-
52
-
-
34248201697
-
Rapid regulation of dopamine transporters by tyrosine kinases in rat neuronal preparations
-
Hoover, B. R., Everett, C. V., Sorkin, A., and Zahniser, N. R. (2007) Rapid regulation of dopamine transporters by tyrosine kinases in rat neuronal preparations. J. Neurochem. 101, 1258-1271
-
(2007)
J. Neurochem.
, vol.101
, pp. 1258-1271
-
-
Hoover, B.R.1
Everett, C.V.2
Sorkin, A.3
Zahniser, N.R.4
-
53
-
-
33644845741
-
Extracellular signal-regulated mitogen-activated protein kinase inhibitors decrease amphetamine-induced behavior and neuropeptide gene expression in the striatum
-
Shi, X., and McGinty, J. F. (2006) Extracellular signal-regulated mitogen-activated protein kinase inhibitors decrease amphetamine-induced behavior and neuropeptide gene expression in the striatum. Neuroscience 138, 1289-1298
-
(2006)
Neuroscience
, vol.138
, pp. 1289-1298
-
-
Shi, X.1
McGinty, J.F.2
-
54
-
-
79951702177
-
How addictive drugs disrupt presynaptic dopamine neurotransmission
-
Sulzer, D. (2011) How addictive drugs disrupt presynaptic dopamine neurotransmission. Neuron 69, 628-649
-
(2011)
Neuron
, vol.69
, pp. 628-649
-
-
Sulzer, D.1
-
55
-
-
19344363221
-
N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux
-
Khoshbouei, H., Sen, N., Guptaroy, B., Johnson, L., Lund, D., Gnegy, M. E., Galli, A., and Javitch, J. A. (2004) N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux. PLoS Biol. 2, E78
-
(2004)
PLoS Biol.
, vol.2
-
-
Khoshbouei, H.1
Sen, N.2
Guptaroy, B.3
Johnson, L.4
Lund, D.5
Gnegy, M.E.6
Galli, A.7
Javitch, J.A.8
-
56
-
-
77951230460
-
The N terminus of monoamine transporters is a lever required for the action of amphetamines
-
Sucic, S., Dallinger, S., Zdrazil, B., Weissensteiner, R., Jørgensen, T. N., Holy, M., Kudlacek, O., Seidel, S., Cha, J. H., Gether, U., Newman, A. H., Ecker, G. F., Freissmuth, M., and Sitte, H. H. (2010) The N terminus of monoamine transporters is a lever required for the action of amphetamines. J. Biol. Chem. 285, 10924-10938
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 10924-10938
-
-
Sucic, S.1
Dallinger, S.2
Zdrazil, B.3
Weissensteiner, R.4
Jørgensen, T.N.5
Holy, M.6
Kudlacek, O.7
Seidel, S.8
Cha, J.H.9
Gether, U.10
Newman, A.H.11
Ecker, G.F.12
Freissmuth, M.13
Sitte, H.H.14
-
57
-
-
79951978579
-
Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters
-
Guptaroy, B., Fraser, R., Desai, A., Zhang, M., and Gnegy, M. E. (2011) Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters. Mol. Pharmacol. 79, 520-532
-
(2011)
Mol. Pharmacol.
, vol.79
, pp. 520-532
-
-
Guptaroy, B.1
Fraser, R.2
Desai, A.3
Zhang, M.4
Gnegy, M.E.5
-
59
-
-
47749083479
-
An intracellular interaction network regulates conformational transitions in the dopamine transporter
-
Kniazeff, J., Shi, L., Loland, C. J., Javitch, J. A., Weinstein, H., and Gether, U. (2008) An intracellular interaction network regulates conformational transitions in the dopamine transporter. J. Biol. Chem. 283, 17691-17701
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 17691-17701
-
-
Kniazeff, J.1
Shi, L.2
Loland, C.J.3
Javitch, J.A.4
Weinstein, H.5
Gether, U.6
-
60
-
-
0035030510
-
SH3 domains. Complexity in moderation
-
Mayer, B. J. (2001) SH3 domains. Complexity in moderation. J. Cell Sci. 114, 1253-1263
-
(2001)
J. Cell Sci.
, vol.114
, pp. 1253-1263
-
-
Mayer, B.J.1
-
61
-
-
65549089736
-
Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3
-
Egaña, L. A., Cuevas, R. A., Baust, T. B., Parra, L. A., Leak, R. K., Hochendoner, S., Peña, K., Quiroz, M., Hong, W. C., Dorostkar, M. M., Janz, R., Sitte, H. H., and Torres, G. E. (2009) Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3. J. Neurosci. 29, 4592-4604
-
(2009)
J. Neurosci.
, vol.29
, pp. 4592-4604
-
-
Egaña, L.A.1
Cuevas, R.A.2
Baust, T.B.3
Parra, L.A.4
Leak, R.K.5
Hochendoner, S.6
Peña, K.7
Quiroz, M.8
Hong, W.C.9
Dorostkar, M.M.10
Janz, R.11
Sitte, H.H.12
Torres, G.E.13
-
62
-
-
2542461709
-
Sodium-dependent neurotransmitter transporters. Oligomerization as a determinant of transporter function and trafficking
-
Sitte, H. H., Farhan, H., and Javitch, J. A. (2004) Sodium-dependent neurotransmitter transporters. Oligomerization as a determinant of transporter function and trafficking. Mol. Interv. 4, 38-47
-
(2004)
Mol. Interv.
, vol.4
, pp. 38-47
-
-
Sitte, H.H.1
Farhan, H.2
Javitch, J.A.3
-
63
-
-
19944429021
-
Amphetamines take two to tango. An oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action
-
Seidel, S., Singer, E. A., Just, H., Farhan, H., Scholze, P., Kudlacek, O., Holy, M., Koppatz, K., Krivanek, P., Freissmuth, M., and Sitte, H. H. (2005) Amphetamines take two to tango. An oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action. Mol. Pharmacol. 67, 140-151
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 140-151
-
-
Seidel, S.1
Singer, E.A.2
Just, H.3
Farhan, H.4
Scholze, P.5
Kudlacek, O.6
Holy, M.7
Koppatz, K.8
Krivanek, P.9
Freissmuth, M.10
Sitte, H.H.11
-
64
-
-
42449094246
-
Substrates dissociate dopamine transporter oligomers
-
Chen, N., and Reith, M. E. (2008) Substrates dissociate dopamine transporter oligomers. J. Neurochem. 105, 910-920
-
(2008)
J. Neurochem.
, vol.105
, pp. 910-920
-
-
Chen, N.1
Reith, M.E.2
-
65
-
-
0038470028
-
Differential effects of amphetamine transport versus dopamine reverse transport on particulate PKC activity in striatal synaptoneurosomes
-
Giambalvo, C. T. (2003) Differential effects of amphetamine transport versus dopamine reverse transport on particulate PKC activity in striatal synaptoneurosomes. Synapse 49, 125-133
-
(2003)
Synapse
, vol.49
, pp. 125-133
-
-
Giambalvo, C.T.1
-
66
-
-
3442895932
-
Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter
-
Lee, K. H., Kim, M. Y., Kim, D. H., and Lee, Y. S. (2004) Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter. Neurochem. Res. 29, 1405-1409
-
(2004)
Neurochem. Res.
, vol.29
, pp. 1405-1409
-
-
Lee, K.H.1
Kim, M.Y.2
Kim, D.H.3
Lee, Y.S.4
-
67
-
-
52949117702
-
Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission
-
Carvelli, L., Blakely, R. D., and DeFelice, L. J. (2008) Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission. Proc. Natl. Acad. Sci. U.S.A. 105, 14192-14197
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 14192-14197
-
-
Carvelli, L.1
Blakely, R.D.2
DeFelice, L.J.3
-
68
-
-
52949112579
-
Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux
-
Binda, F., Dipace, C., Bowton, E., Robertson, S. D., Lute, B. J., Fog, J. U., Zhang, M., Sen, N., Colbran, R. J., Gnegy, M. E., Gether, U., Javitch, J. A., Erreger, K., and Galli, A. (2008) Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux. Mol. Pharmacol. 74, 1101-1108
-
(2008)
Mol. Pharmacol.
, vol.74
, pp. 1101-1108
-
-
Binda, F.1
Dipace, C.2
Bowton, E.3
Robertson, S.D.4
Lute, B.J.5
Fog, J.U.6
Zhang, M.7
Sen, N.8
Colbran, R.J.9
Gnegy, M.E.10
Gether, U.11
Javitch, J.A.12
Erreger, K.13
Galli, A.14
-
69
-
-
0034667557
-
Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A
-
Bauman, A. L., Apparsundaram, S., Ramamoorthy, S., Wadzinski, B. E., Vaughan, R. A., and Blakely, R. D. (2000) Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A. J. Neurosci. 20, 7571-7578
-
(2000)
J. Neurosci.
, vol.20
, pp. 7571-7578
-
-
Bauman, A.L.1
Apparsundaram, S.2
Ramamoorthy, S.3
Wadzinski, B.E.4
Vaughan, R.A.5
Blakely, R.D.6
-
70
-
-
34247251277
-
Isoform specificity of protein kinase Cs in synaptic plasticity
-
Sossin, W. S. (2007) Isoform specificity of protein kinase Cs in synaptic plasticity. Learn Mem. 14, 236-246
-
(2007)
Learn Mem.
, vol.14
, pp. 236-246
-
-
Sossin, W.S.1
-
71
-
-
0037155257
-
Protein kinase C (PKC)η-mediated PKC μ activation modulates ERK and JNK signal pathways
-
Brändlin, I., Hübner, S., Eiseler, T., Martinez-Moya, M., Horschinek, A., Hausser, A., Link, G., Rupp, S., Storz, P., Pfizenmaier, K., and Johannes, F. J. (2002) Protein kinase C (PKC)η-mediated PKC μ activation modulates ERK and JNK signal pathways. J. Biol. Chem. 277, 6490-6496
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6490-6496
-
-
Brändlin, I.1
Hübner, S.2
Eiseler, T.3
Martinez-Moya, M.4
Horschinek, A.5
Hausser, A.6
Link, G.7
Rupp, S.8
Storz, P.9
Pfizenmaier, K.10
Johannes, F.J.11
-
72
-
-
0037105039
-
PKCα-mediated ERK, JNK, and p38 activation regulates the myogenic program in human rhabdomyosarcoma cells
-
Mauro, A., Ciccarelli, C., De Cesaris, P., Scoglio, A., Bouché, M., Molinaro, M., Aquino, A., and Zani, B. M. (2002) PKCα-mediated ERK, JNK, and p38 activation regulates the myogenic program in human rhabdomyosarcoma cells. J. Cell Sci. 115, 3587-3599
-
(2002)
J. Cell Sci.
, vol.115
, pp. 3587-3599
-
-
Mauro, A.1
Ciccarelli, C.2
De Cesaris, P.3
Scoglio, A.4
Bouché, M.5
Molinaro, M.6
Aquino, A.7
Zani, B.M.8
-
73
-
-
1542275216
-
Involvement of the ERK signaling cascade in protein kinase C-mediated cell cycle arrest in intestinal epithelial cells
-
Clark, J. A., Black, A. R., Leontieva, O. V., Frey, M. R., Pysz, M. A., Kunneva, L., Woloszynska-Read, A., Roy, D., and Black, J. D. (2004) Involvement of the ERK signaling cascade in protein kinase C-mediated cell cycle arrest in intestinal epithelial cells. J. Biol. Chem. 279, 9233-9247
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9233-9247
-
-
Clark, J.A.1
Black, A.R.2
Leontieva, O.V.3
Frey, M.R.4
Pysz, M.A.5
Kunneva, L.6
Woloszynska-Read, A.7
Roy, D.8
Black, J.D.9
-
74
-
-
33745353037
-
Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2
-
Wen-Sheng, W. (2006) Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2. Cancer Lett. 239, 27-35
-
(2006)
Cancer Lett.
, vol.239
, pp. 27-35
-
-
Wen-Sheng, W.1
-
75
-
-
0034817385
-
Dopamine regulates Na-K-ATPase in alveolar epithelial cells via MAPK-ERK-dependent mechanisms
-
Guerrero, C., Lecuona, E., Pesce, L., Ridge, K. M., and Sznajder, J. I. (2001) Dopamine regulates Na-K-ATPase in alveolar epithelial cells via MAPK-ERK-dependent mechanisms. Am. J. Physiol. Lung Cell Mol. Physiol. 281, L79-L85
-
(2001)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.281
-
-
Guerrero, C.1
Lecuona, E.2
Pesce, L.3
Ridge, K.M.4
Sznajder, J.I.5
-
76
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways. Regulation and physiological functions
-
Pearson, G., Robinson, F., Beers Gibson, T., Xu, B. E., Karandikar, M., Berman, K., and Cobb, M. H. (2001) Mitogen-activated protein (MAP) kinase pathways. Regulation and physiological functions. Endocr. Rev. 22, 153-183
-
(2001)
Endocr. Rev.
, vol.22
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Beers Gibson, T.3
Xu, B.E.4
Karandikar, M.5
Berman, K.6
Cobb, M.H.7
-
77
-
-
34247368172
-
Lining the pockets of kinases and phosphatases
-
Gold, M. G., Barford, D., and Komander, D. (2006) Lining the pockets of kinases and phosphatases. Curr. Opin. Struct. Biol. 16, 693-701
-
(2006)
Curr. Opin. Struct. Biol.
, vol.16
, pp. 693-701
-
-
Gold, M.G.1
Barford, D.2
Komander, D.3
|